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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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The Impact of Natural Bioactive Compounds on Human Health and Disease
edited by
submission deadline 31 Dec 2025 | 4 articles | Viewed by 4483 | Submission Open
Keywords: natural product chemistry; nuclear magnetic resonance; structural elucidation; herbal drug
(This special issue belongs to the Section Molecular Pharmacology)
Research Progress of Metabolomics in Health and Disease submission deadline 31 Dec 2025 | 6 articles | Viewed by 4331 | Submission Open
Keywords: metabolomics; health; diseases; target metabolites; mass spectrometry; hyphenated techniques
(This special issue belongs to the Section Molecular Biology)
Targeted Delivery of Nucleic Acids
edited by Yong-Serk Park
submission deadline 31 Dec 2025 | 2 articles | Viewed by 3585 | Submission Open
Keywords: nucleic acid delivery; gene delivery; pDNA delivery; siRNA delivery; miRNA delivery; mRNA delivery; CRISPR-Cas delivery; nanoparticle; lipid nanoparticle; targeted therapy
(This special issue belongs to the Section Molecular Biology)
Recent Progress in Metabolic Diseases
edited by
submission deadline 31 Dec 2025 | 2 articles | Viewed by 1842 | Submission Open
Keywords: metabolic diseases; enzymes related to metabolic disorders; inborn errors of metabolism; inherited single-gene anomalies; molecular diagnostics in metabolic disorders
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Advancements in Diagnostic and Preventive Pharmacogenomics
edited by Alireza Tafazoli
submission deadline 31 Dec 2025 | 1 articles | Viewed by 1559 | Submission Open
Keywords: genome profiling; pharmacogenetic analysis; diagnostic pharmacogenomics; pre-emptive pharmacogenomics; advanced genotyping technologies
(This special issue belongs to the Section Molecular Pharmacology)
Advances in the Relationship Between Diet and Insulin Resistance
edited by
submission deadline 31 Dec 2025 | 1 articles | Viewed by 1526 | Submission Open
Keywords: insulin resistance; lipotoxicity; lipid metabolism; type 2 diabetes mellitus; dietary lipids; lipidomics
(This special issue belongs to the Section Molecular Endocrinology and Metabolism)
Advances in Forensic Molecular Biology and Genetics
edited by
submission deadline 31 Dec 2025 | Viewed by 919 | Submission Open
Keywords: nuclear and mt-DNA; rapid DNA analysis; next-generation sequencing; mRNA analysis; microbiome analysis; barcode DNA; time since deposition; fluid identification; DNA phenotyping; DNA ancestry
(This special issue belongs to the Section Molecular Biology)
Molecular Insights into RNA Diseases
edited by
submission deadline 31 Dec 2025 | 1 articles | Viewed by 721 | Submission Open
Keywords: RNA splicing; RNA modification; RNA processing; translation; RNA transport
(This special issue belongs to the Section Molecular Genetics and Genomics)
Emerging Trends in Enzymology submission deadline 31 Dec 2025 | Viewed by 560 | Submission Open
(This special issue belongs to the Section Biochemistry)
Molecular Entomology of Insects of Economic Importance: Advanced Molecular Approaches for Insect Pest Management
edited by
submission deadline 31 Dec 2025 | Viewed by 334 | Submission Open
Keywords: molecular entomology; insect pests; agricultural pests; disease vectors; beneficial insects; CRISPR; RNA interference; genome-wide approaches; computational biology; nanotechnology
(This special issue belongs to the Section Molecular Biology)
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