Protein and Protease for Tooth and Bone Formation
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Biology".
Deadline for manuscript submissions: closed (30 August 2019) | Viewed by 313
Special Issue Editors
Interests: tooth enamel formation; tooth dentin formation; protein; protease; physiologically active substances; ameloblasts; odontoblasts; dental pulp
Interests: bone formation; tooth enamel formation; osteoclasts, osteoblasts; protein; protease; physiologically active substances
Special Issue Information
Dear Colleagues,
Hydroxyapatite (HA) is the main inorganic component in mineralized tissues such as bone, dentin, enamel, and cement. In contrast to simple crystallization of inorganic substances from solution, the formation of hard tissue HA is a complex process that is controlled by various proteins, proteases, proteoglycans, and physiologically active compounds. Furthermore, the gene expression of these organic components and the dynamics of mineral components are regulated by intracellular factors of the cells responsible for the formation of hard tissues. However, the associations among the organic components as well as between the organic and mineral components are largely unknown, and the regulatory mechanisms of the cells involved also remain to be elucidated.
In this Special Issue, associations among the factors involved in the mechanisms of biological mineralization will be discussed, covering matrix components, hard tissue-forming cells, regulatory factors, and mineral components.
Prof. Dr. Yasuo Yamakoshi
Dr. Takeo Karakida
Guest Editors
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Keywords
- tooth formation
- tooth regeneration
- cytokine
- extracellular matrix
- protease
- endocytosis
- apoptosis
- ameloblasts
- odontoblasts
- dental pulp
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