Molecular Mechanisms of Neurodevelopment, Neuroprotection, and Brain Health
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Neurobiology".
Deadline for manuscript submissions: 31 December 2026 | Viewed by 136
Special Issue Editor
Interests: ischemic stroke; animal models; blood–brain barrier dysfunction; ischemic brain damage; neu-roprotection; new therapies; magnetic resonance imaging; clinical biomarkers of brain damage
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Understanding the molecular mechanisms underlying neurodevelopment, neuroprotection, and brain health is essential in addressing neurological disorders. In particular, ischemic stroke remains a leading cause of disability and mortality worldwide, highlighting the need for deeper insights into ischemic brain damage and blood–brain barrier dysfunction, as well as the development of effective therapeutic strategies.
This Special Issue will showcase high-quality contributions that explore the molecular and cellular basis of brain function and injury, with a special focus on ischemic stroke and neuroprotection. It will bridge basic and clinical research, fostering translational approaches that contribute to the development of novel therapies and diagnostic tools. This topic aligns with the scope of the International Journal of Molecular Sciences (IJMS) by addressing molecular mechanisms and their biomedical applications.
Topics of interest include, but are not limited to, ischemic stroke mechanisms, neurodevelopmental processes, blood–brain barrier dysfunction and protection, neuroinflammation, neurovascular unit alterations, and brain repair. Submissions may include original research articles, reviews, and translational or clinical studies. The use of advanced methodologies such as animal models, magnetic resonance imaging, and the identification of biomarkers of brain injury is particularly encouraged.
Research in this area is designed to elucidate the molecular mechanisms underlying neurodevelopment, neuroprotection, and brain health through both basic and clinical studies. Experimental work using animal models of ischemic stroke is combined with clinical research to better understand ischemic brain damage and blood–brain barrier dysfunction or protection. Through this integrated approach, we aim to identify and validate novel therapeutic strategies and neuroprotective interventions, supported by advanced techniques such as magnetic resonance imaging and the analysis of clinical biomarkers of brain injury. In this context, we invite the submission of scientific contributions addressing these topics, including original research, translational studies, and clinical investigations that can advance knowledge in this field.
Dr. Ramón Iglesias-Rey
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- cerebral ischemia
- neurovascular coupling
- brain plasticity
- endothelial dysfunction
- neu-roinflammation
- tissue repair
- imaging biomarkers
- stroke recovery
- molecular neurobiology
- therapeutic targets
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