Special Issue "Multi-Omics and Precision Medicine of Leukemia"

Dear Colleagues,

High-throughput sequencing technologies can characterize cancer samples at multiple molecular levels. The integrative analysis of multi-omics datasets is a core and critical step for precision medicine frameworks that can help in understanding patient and disease-specific variations. A single-omics approach cannot comprehensively view a disease's genetic, biochemical, metabolic, proteomic, and epigenetic processes. To address the significant challenges of precision medicine in oncology (including patient phenotyping, biomarker discovery, and drug repurposing), computational multi-omics approaches based on machine learning techniques are proposed as promising tools to profile patients in multiple dysfunctions in a biological system that cancer mechanisms may alter. Analysis of datasets generated by multi-omics sequencing requires the development of computational methods, covering data integration, statistical methods, and artificial intelligence systems to derive actionable knowledge from the data. Based on bioinformatics technologies and methods to explore scientific issues related to multi-omics and precision medicine focusing on leukemia, a Special Issue of Genes is being issued. Authors are encouraged to submit innovative tools describing the integration of heterogeneous data, solving multi-omics machine learning methods and frameworks for data complexity, reviews or comparisons of existing tools and methods, and manuscripts dealing with bioinformatics analysis methods, ultimately providing theoretical references and actionable results for clinical practice.

Prof. Dr. Dong Wang
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Genes is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• multi-omics data
• precision medicine
• leukemia
• bioinformatics
• computational approach