Special Issue "Population Genetics and Genomics of Opportunistic and Drug-Resistant Bacterial Pathogens: Dealing with Complexity"
Deadline for manuscript submissions: closed (30 September 2018)
The bacterial resistance to antimicrobial agents is presently an emerging global threat with a predicted health disaster on the 2050 horizon. Multi-drug resistance mainly concerns opportunistic bacteria, such as healthcare-associated pathogens and environmental pathogens, of which dynamics are influenced by global changes. These bacteria display versatile behaviors and adaptive ability, mainly based on a wide metabolic repertory and their great resistance to physicochemical agents, these traits resulting from complexity at various biological levels: Population genetics, mode of evolution, structure and content of the genome, organization in species complex rather than in true species, association of pathoadaptative traits rather than specific discrete virulence factors, etc. This complexity precludes the use of model organisms as the standard of a bacterial species, and makes population approaches obligatory. The development of new generation sequencing allows the study of microbial genetics and genomics at the population level, with major advances in phylotaxonomy, pathogenesis, epidemiology, infection control, and, more generally, in the understanding of the infectious success of opportunistic, healthcare-associated and drug-resistant pathogens.
This Special Issue is open to researchers willing to contribute significant original research, relevant observations, new concept or reviews in population genetics and the genomics of bacteria involved in opportunistic infections.
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Genes is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- Opportunistic human pathogens
- bacterial population studies
- bacterial genomics
- resistance to antimicrobial agents
- healthcare-associated infection
- environmental pathogens