Computational Epigenetics

Dear Colleagues,

Genomics, transcriptomics, and epigenetics fields have experienced a data revolution through the implementation of next-generation sequencing technologies and, more recently, the appearance of single-cell methodologies. In this context, computational biology plays a central role in the analysis and integration of the unprecedented amount of data generated in these fields and in the development of efficient, accessible and sustainable computational tools.

This Special Issue will be focused on the computational analysis of chromatin modifications, gene expression, and RNA processing data in healthy and diseased conditions, as well as in the development of computational tools to analyze epigenomics and transcriptomics high-throughput data, both from bulk and single-cell studies. Manuscripts on the following and related topics are welcome.

• Computational analysis of large datasets in the following and related areas
  • Chromatin modifications and gene expression
  • Epigenetics and disease
  • Single-cell transcriptomics and epigenomics
  • Chromatin structure
• Evolutionary epigenetics/epigenomics
• Computational methods in epigenetics, including methods for processing bulk and single cell omics data, high-dimensionality visualization methods, methods for population epigenetics, AI/ML methods for data interpretation and prediction, theoretical/mathematical models of epigenetic regulation of gene expression
• High-throughput perturbation experiments and associated computational tools
• Epigenetic databases

Dr. Roderic Guigó Serra
Dr. Silvia Pérez Lluch
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Epigenomes is an international peer-reviewed open access quarterly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1500 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.