Special Issue "Noncanonical Nucleobases"
A special issue of Crystals (ISSN 2073-4352). This special issue belongs to the section "Biomolecular Crystals".
Deadline for manuscript submissions: closed (21 December 2018)
Special Issue Editor
Interests: supramolecular chemistry; crystal engineering; canonical and epigenetic nucleobases; hydrogen bond; halogen bond; X-ray single-crystal; X-ray powder diffraction; theoretical calculations; AFM
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Naturally-occurring modified nucleobases, next to the four canonical nucleobases, extend the chemical information content of DNA and RNA, but their role in regulating the basic functions in a cell is still largely unexplored. In addition, over the past two decades chemically modified nucleobases have been developed as versatile tool for chemical fine-tuning of artificial DNA in the emerging area of synthetic biology. Indeed, unnatural base pairing may possess higher specificity and thermal stability through suitable design of artificial nucleobases and yield an artificially expanded genetic information system.
The aim of this forthcoming Special Issue, "Noncanonical Nucleobases", is not only to present new crystal structures, but also to discuss the nature and the strength of interactions in biological systems containing such important molecules. However, theoretical analyses concerning modified nucleobases, if related to their crystal structure, are also appropriate.
It is a pleasure to invite you to submit a manuscript for this Special Issue; regular articles, communications, as well as reviews are all welcome.
Prof. Dr. Gustavo Portalone
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Crystals is an international peer-reviewed open access monthly journal published by MDPI.
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Keywords
- Noncanonical DNA base
- Noncanonical RNA base
- Noncanonical base-pairing
- Noncovalent interactions
- Crystal structure
- Quantum chemical calculations
- Energetics and structure prediction
