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Current Issues in Molecular Biology publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Stem Cell-Derived Cells and Bioengineering: Molecular Bases in Regeneration and Disease Research

edited by Aylin Acun

submission deadline 28 Feb 2026 | Viewed by 57 | Submission Open

Keywords: stem cells; regenerative medicine; bioengineering; disease modeling; organoids; tissue engineering; decellularization; bioprinting

(This special issue belongs to the Section Molecular Medicine)

Multiomics of Cancer Research in Human and Animals

edited by

Kyuhyung Choi

submission deadline 28 Feb 2026 | Viewed by 56 | Submission Open

Keywords: multiomics; cancer; epigenomics; proteomics; metabolomics

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

Molecular Insights and Therapeutic Advances in Hematological Disorders, 2nd Edition

edited by

Eleni Gavriilaki

submission deadline 28 Feb 2026 | Viewed by 35 | Submission Open

Keywords: acute leukemia; myeloproliferative neoplasms; lymphoma; multiple myeloma; hemoglobinopathies; hemophilia

(This special issue belongs to the Section Molecular Medicine)

Advances in Drug Design and Drug Discovery

edited by

Arjun Singh

submission deadline 5 Mar 2026 | Viewed by 70 | Submission Open

Keywords: drug discovery; drug design; artificial intelligence; structure-based drug design; omics; biologics; precision medicine; drug repurposing

(This special issue belongs to the Section Molecular Pharmacology)

Molecular Mechanisms Driving Cancer Progression and Metastasis

edited by

Karolina Bajdak-Rusinek

submission deadline 15 Mar 2026 | Viewed by 48 | Submission Open

Keywords: cancer progression; metastasis; epithelial– mesenchymal transition (EMT); tumor plasticity; tumor microenvironment; signaling pathways; therapy resistance

(This special issue belongs to the Section Molecular Medicine)

Mechanisms and Pathophysiology of Obesity

edited by Padmamalini Baskaran

submission deadline 20 Mar 2026 | 4 articles | Viewed by 7525 | Submission Open

Keywords: understanding genetic factors for obesity at the molecular level; understanding environmental factors for obesity at the molecular level; contribution of insulin resistance to obesity and ways to combat; circadian misalignment– molecular level understanding of its contribution to obesity and ways to mitigate it; effective and individualized obesity treatment strategies for stress; molecular understanding of the influence of parental obesity on childhood overweight; molecular mechanisms of maternal smoking on childhood obesity; therapeutic interventions for obesity through recombinant hormones; role of gut hormones in the treatment of obesity; development of new digital tools for weight management interventions

(This special issue belongs to the Section Molecular Medicine)

Advances in Molecular Biology and Therapeutics: From Natural Products to Pharmaceutical Agents

edited by

Budimir S. Ilić

submission deadline 30 Mar 2026 | Viewed by 54 | Submission Open

Keywords: natural products; molecular biology; medicinal chemistry; drug discovery; therapeutic agents; molecular dynamics; QSAR modeling; ADMET profiling; antimicrobial resistance; translational pharmacology

(This special issue belongs to the Section Molecular Pharmacology)

Molecular Biology in Drug Design and Precision Therapy

edited by

Cristina Manuela Dragoi

Ion-Bogdan Dumitrescu

and

Alina Crenguta Nicolae

submission deadline 31 Mar 2026 | 12 articles | Viewed by 23329 | Submission Open

Keywords: molecular biology; drug design; molecular targets; disease mechanisms; structural biology; computational chemistry; pharmacology; precision medicine; molecular pathways; personalized therapy; drug research

(This special issue belongs to the Section Molecular Medicine)

Molecular Insights into Multifactorial Causes of Insulin Resistance in Obesity

edited by Bogdana Virgolici

submission deadline 31 Mar 2026 | 7 articles | Viewed by 21503 | Submission Open

Keywords: obesity; inflammation; oxidative stress; insulin resistance; caloric restriction

(This special issue belongs to the Section Molecular Medicine)

Molecular Mechanisms and Regulation in Allergy and Immune Diseases, Immunodeficiencies, 2nd Edition

edited by

Kinga Lis

submission deadline 31 Mar 2026 | 4 articles | Viewed by 20291 | Submission Open

Keywords: allergy and hypersensitivity mechanisms; cross-reactivity in allergy; component resolved diagnostic (CRD); immunodeficiencies; experimental research methods in allergology; biochemical properties of allergens

(This special issue belongs to the Section Molecular Medicine)

Natural Products as Potential Sources of Antidiabetic Compounds, 2nd Edition

edited by

Hidayat Hussain

submission deadline 31 Mar 2026 | 7 articles | Viewed by 13515 | Submission Open

Keywords: natural products; natural product derivatives; antidiabetic agents; α -glucosidase inhibitors; amylase inhibitors; PTP1B inhibitors; DPP-4 inhibitors; molecular level; kinetic studies; in vitro studies; in vivo studies; computational methods; mode of action

(This special issue belongs to the Section Bioorganic Chemistry and Medicinal Chemistry)

Molecular Research in Bioactivity of Natural Products, 3rd Edition

edited by

Magdalena Bartnik

and

Wirginia Kukula-Koch

submission deadline 31 Mar 2026 | 2 articles | Viewed by 4813 | Submission Open

Keywords: molecular research; molecular properties; metabolic pathway; phytochemicals; natural products; apoptosis; bioactivity assessment; chemical composition; therapeutic targets

(This special issue belongs to the Section Bioorganic Chemistry and Medicinal Chemistry)

The Significance of Transcription Factors, miRNAs, and lncRNAs in Anticancer Drug Development, 2nd Edition

edited by

Ru Chih C. Huang

and

Kotohiko Kimura

submission deadline 31 Mar 2026 | 3 articles | Viewed by 3751 | Submission Open

Keywords: transcription factors; microRNAs (miRNAs); long non-coding RNAs (lncRNAs); anticancer drugs; cancer; coactivators

(This special issue belongs to the Section Molecular Medicine)

Targeted Therapeutic Approaches in Cancer: Combining Natural Compounds and Conventional Drugs

edited by

Alok Bhushan

submission deadline 31 Mar 2026 | 3 articles | Viewed by 3481 | Submission Open

Keywords: natural compounds; cancer; repurposing; combination; polychemotherapy; pharmaceuticals; nutraceuticals; molecular targets; metabolomics; immunotherapy

(This special issue belongs to the Section Molecular Medicine)

Effects of Nanoparticles on Living Organisms, 3rd Edition

edited by

Yoshitaka Miyamoto

submission deadline 31 Mar 2026 | 1 articles | Viewed by 2500 | Submission Open

Keywords: nanoparticles; particulate matter; medicine; prevention; diagnosis; drug delivery; environment; nanoparticles functionalization; in vitro/in vivo evaluation; 3D model; ADME; toxicity; biomedical applications; respiratory and cardiovascular diseases; immunological; inflammatory; and allergic diseases

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

Therapeutic Effects of Natural Bioactive Compounds in the Management of Human Diseases: 2nd Edition

edited by

Rossana Morabito

and

Sara Spinelli

submission deadline 31 Mar 2026 | 2 articles | Viewed by 1877 | Submission Open

Keywords: natural bioactive compound; human health; chronic diseases; molecular target; oxidative stress; inflammation; cancer; diabetes

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

Precision Molecular Oncology: From Tumor Biomarker Discovery to Next-Generation Drug Delivery

edited by

Farhadul Islam

submission deadline 31 Mar 2026 | Viewed by 962 | Submission Open

Keywords: precision oncology; molecular pathology; personalized treatment; tumor marker; biomarkers; multi-omics; drug discovery; nanocarriers; drug delivery; clinical management

(This special issue belongs to the Section Molecular Medicine)

Molecular Basis of Autoimmune Diseases

edited by

Ranjeet Singh Mahla

submission deadline 31 Mar 2026 | 1 articles | Viewed by 882 | Submission Open

Keywords: autoimmune diseases; immune regulation; molecular mechanisms; genetic predisposition; epigenetics; cytokines; biomarkers; immune checkpoints; targeted therapies; genomics; transcriptomics; proteomics; systems biology; inflammation; immune tolerance

(This special issue belongs to the Section Molecular Medicine)

Molecular Roles of Neutrophil Extracellular Traps in Immune Responses and Disease

edited by Sofía S. Jerez

submission deadline 31 Mar 2026 | 1 articles | Viewed by 822 | Submission Open

Keywords: neutrophils; NET; inflammation; chronic diseases; cell death

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

Molecular Mechanisms and Therapeutic Advances in Hypertension Management and Vascular Health

edited by

Federica Fogacci

Arrigo Francesco Giuseppe Cicero

and

Claudio Borghi

submission deadline 31 Mar 2026 | 1 articles | Viewed by 815 | Submission Open

Keywords: hypertension; vascular aging; endothelial dysfunction; gestational hypertension; metabolic disorders; therapeutic strategies in hypertension management

(This special issue belongs to the Section Molecular Medicine)

Molecular Insights into Gut Biology: Stem Cells, Organoids, and Microbiota–Immune Interactions

edited by

Shaoyi Zhang

submission deadline 31 Mar 2026 | 1 articles | Viewed by 461 | Submission Open

Keywords: intestinal stem cells; intestinal organoids; gut– microbiota interaction; mucosal immunology; molecular mechanisms; gut epithelial regeneration; microbiota– immune crosstalk; organoid disease models; intestinal homeostasis; molecular gut biology

(This special issue belongs to the Section Molecular Microbiology)

Molecular Research on Free Radicals and Oxidative Stress—2nd Edition

edited by

Mosharraf Sarker

submission deadline 31 Mar 2026 | Viewed by 206 | Submission Open

Keywords: oxidative stress; free radicals; reactive oxygen species (ROS); gene regulation; antioxidants; mitochondrial dysfunction; insulin resistance; inflammation; autophagy

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

Emerging Trends for Genome-Wide Association Studies in Complex Disease Genetics

edited by

Xiaowei Wu

submission deadline 31 Mar 2026 | Viewed by 201 | Submission Open

Keywords: GWAS; polygenic risk scores; rare variants; structural variants; multi-omics; Mendelian randomization; population structure and relatedness; machine learning; Bayesian models; stochastic models

(This special issue belongs to the Section Bioinformatics and Systems Biology)

The Molecular Pathways Involved in Atopic Dermatitis: Implications for Targeted Therapy

edited by

Ciro Martins Gomes

submission deadline 31 Mar 2026 | Viewed by 193 | Submission Open

Keywords: atopic dermatitis; biological products; cytokines; Th2 cells; eczema; Janus kinase inhibitors

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

Scoliosis and Spinal Disorders: Molecular Biomarkers and Therapeutic Strategies

edited by

Angelos Kaspiris

submission deadline 31 Mar 2026 | Viewed by 119 | Submission Open

Keywords: intracellular interactions during the progression of spinal disorders; molecular signaling in scoliosis; growth factor expression in spinal disorders and deformities; biomarkers; molecular-driven treatment

(This special issue belongs to the Section Molecular Medicine)

Featured Papers in Bioinformatics and Systems Biology

edited by

Howard H. Yang

submission deadline 31 Mar 2026 | Viewed by 94 | Submission Open

Keywords: bioinformatics; omics; genomics and transcriptomics sequence analyses; dynamic modeling

(This special issue belongs to the Section Bioinformatics and Systems Biology)

Emerging Trends in Bioinformatics and Computational Biology

edited by Haijun Gong

submission deadline 31 Mar 2026 | Viewed by 86 | Submission Open

Keywords: bioinformatics; computational biology; genomics; proteomics; metabolomics; multi-omics; machine learning; algorithms; big data; molecular diagnostics; personalized medicine; data visualization

(This special issue belongs to the Section Bioinformatics and Systems Biology)

Molecular Studies of Bioactive Compounds and Their Therapeutic Potential

edited by Sanja Radman and

Ivana Carev

submission deadline 31 Mar 2026 | Viewed by 83 | Submission Open

Keywords: bioactive compounds; molecular mechanisms; structural elucidation; molecular targets; omics approaches

(This special issue belongs to the Section Bioorganic Chemistry and Medicinal Chemistry)

Advances in Oxidative Stress and Inflammation

edited by Md. Sohanur Rahman

submission deadline 31 Mar 2026 | Viewed by 79 | Submission Open

Keywords: oxidative stress; inflammation; redox signaling; mitochondrial dysfunction; antioxidant therapy

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

Antimicrobial or Antibiofilm Activity of Biodegradable Substances

edited by

Miyako Yoshida

submission deadline 31 Mar 2026 | Viewed by 49 | Submission Open

Keywords: antibacterial; antibiofilm; antimicrobial; biodegradable; drug-resistance

(This special issue belongs to the Section Molecular Microbiology)

Advancements in Mass Spectrometry-Based Lipidomics for Molecular Biology Research

edited by Hua Tian

submission deadline 31 Mar 2026 | Viewed by 43 | Submission Open

Keywords: lipidomics; high resolution; spatial omics; single cell

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

Molecular Research on Growth Hormones and Related Hormones and Peptides

edited by Hugo Alberto Barrera-Saldaña

submission deadline 31 Mar 2026 | Viewed by 43 | Submission Open

Keywords: growth hormones; insulin-like growth factor; prolactin; vasoinhibin; antiangiogenic

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

Genetics and Genomics Research of Autism Spectrum Disorders

edited by

Golder N. Wilson

submission deadline 31 Mar 2026 | Viewed by 40 | Submission Open

Keywords: autism; neurodevelopmental disorders; genomics; copy number variants; next-generation sequencing

(This special issue belongs to the Section Molecular Medicine)

Neural Networks in Molecular and Cellular Neurobiology

edited by

Paschalis Theotokis

submission deadline 31 Mar 2026 | Viewed by 32 | Submission Open

Keywords: neural networks; neuroplasticity; intracellular signaling; computational neuroscience; artificial intelligence; neuromorphic computing

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

Complex Molecular Mechanism of Monogenic Diseases: 3rd Edition

edited by

Grzegorz Wegrzyn

submission deadline 20 Apr 2026 | 2 articles | Viewed by 15700 | Submission Open

Keywords: cystic fibrosis; sickle cell disease; duchenne muscular dystrophy; inherited monogenic disease; molecular mechanisms

(This special issue belongs to the Section Molecular Medicine)

Natural Product Drug Activity and Biomedicine Application

edited by

Anna Makuch-Kocka

submission deadline 30 Apr 2026 | 7 articles | Viewed by 13316 | Submission Open

Keywords: natural products; signaling pathways; epignetic regulation; cell communication; molecular biology

(This special issue belongs to the Section Molecular Pharmacology)

Intestinal Inflammation: From Molecular Mechanisms to Therapeutic Strategies

edited by

Raffaele Pellegrino

and

Antonietta Gerarda Gravina

submission deadline 30 Apr 2026 | 3 articles | Viewed by 7345 | Submission Open

Keywords: inflammatory bowel disease; celiac disease; Crohn's Disease; ulcerative colitis; colitis; hemorrhoidal disease

(This special issue belongs to the Section Molecular Medicine)

The Role of Bioactives in Inflammation, 2nd Edition

edited by

Chan-Yen Kuo

submission deadline 30 Apr 2026 | 4 articles | Viewed by 3361 | Submission Open

Keywords: anti-inflammation; bioactives; drug research and development; inflammatory diseases; natural products; signaling; synthesized compounds

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

Mechanistic Insights into the Antioxidant Activity of Bioorganic Molecules: A Chemical Perspective

edited by

Tatjana S. Radosavljević

submission deadline 30 Apr 2026 | 2 articles | Viewed by 2525 | Submission Open

Keywords: antioxidant mechanisms; bioorganic molecules; redox -active compounds; molecular reactivity; oxidative stress modulation

(This special issue belongs to the Section Bioorganic Chemistry and Medicinal Chemistry)

Pathogenesis, Diagnosis and Treatment of Skin and Sexually Transmitted Diseases

edited by

Maria Eleni Manthou

, Efstratios Vakirlis and

Iasonas Dermitzakis

submission deadline 30 Apr 2026 | 2 articles | Viewed by 2499 | Submission Open

Keywords: pathogenesis; diagnosis; treatment; dermatology; STDs; molecular; immunology; inflammation; genomics; precision

(This special issue belongs to the Section Molecular Medicine)

Molecular Research on Virus-Related Infectious Disease

edited by Guangcai Duan and

Shuaiyin Chen

submission deadline 30 Apr 2026 | 1 articles | Viewed by 1453 | Submission Open

Keywords: molecular diagnosis of viruses; viral genomics; host– virus interactions; molecular pathways; therapeutic targets; vaccine development

(This special issue belongs to the Section Molecular Microbiology)

Epigenetic Changes in Cancer: Mechanisms, Biomarkers, and Therapeutic Strategies

edited by Priscilla Brebi-Mieville

submission deadline 30 Apr 2026 | 1 articles | Viewed by 1204 | Submission Open

Keywords: epigenetic mechanisms in cancer; epigenetic-based therapies; precision oncology and epigenetics; epigenetic drug development; tumor heterogeneity and epigenetics; epigenetic reprogramming

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

Molecules at Play in Cardiovascular Diseases

edited by

Dumitru A. Iacobas

submission deadline 30 Apr 2026 | 3 articles | Viewed by 1183 | Submission Open

Keywords: arrythmias; arteriosclerosis; congenital heart disease; coronary disease; diabetic cardiomyopathy; dilated cardiomyopathy; endocarditis; high blood pressure; hypertrophic cardiomyopathy; valvular heart diseases

(This special issue belongs to the Section Molecular Medicine)

Oxidative Stress in Cancer Biology

edited by

Eugenia Yiannakopoulou

submission deadline 30 Apr 2026 | Viewed by 142 | Submission Open

Keywords: reactive oxygen species (ROS); redox homeostasis; oxidative DNA damage; antioxidant defense mechanisms; Nrf2 signaling pathway; mitochondrial dysfunction; tumor microenvironment; cancer cell survival and proliferation

(This special issue belongs to the Section Molecular Medicine)

Biochar as a Soil Amendment: Unraveling Molecular Mechanisms Underpinning Plant Growth Promotion via Gene Expression and Regulatory Networks

edited by

Kumuduni Palansuriya

submission deadline 30 Apr 2026 | Viewed by 119 | Submission Open

Keywords: biochar; soil amendment; plant growth promotion; soil health; soil fertility; nutrient availability; rhizosphere interactions; agricultural productivity; sustainable soil management; organic amendments

(This special issue belongs to the Section Molecular Plant Sciences)

Molecular Biology and Biochemistry of Cannabis: Exploring the Genetic and Metabolic Pathways

edited by Craig M. Schluttenhofer

submission deadline 30 Apr 2026 | Viewed by 96 | Submission Open

Keywords: cannabis sativa; molecular biology; phytochemical pathways; cannabinoid receptors; genomics; neurobiology; immunomodulation; plant– microbe interactions

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

Natural Products to Pharmaceutical Agents: Molecular Mechanisms and Therapeutic Applications

edited by Lele Yang

submission deadline 30 Apr 2026 | Viewed by 40 | Submission Open

Keywords: molecular biology; type 2 diabetes mellitus; natural products; drug discovery; therapeutic applications

(This special issue belongs to the Section Bioorganic Chemistry and Medicinal Chemistry)

Molecular Mechanisms of Intervertebral Disc Degeneration and Regeneration

edited by

Koji Akeda

, Nobuyuki Fujita and Akira Shinohara

submission deadline 30 Apr 2026 | Viewed by 36 | Submission Open

Keywords: intervertebral disc degeneration; disc regenerative therapy; biomechanics of the spine; molecular mechanisms; degenerative lumbar disorders

(This special issue belongs to the Section Molecular Medicine)

Molecular and Immunological Research on Colorectal Cancer: Pathogenesis, Microenvironment, and Future Therapies

edited by Mónica G Mendoza-Rodríguez

submission deadline 30 Apr 2026 | Viewed by 35 | Submission Open

Keywords: colorectal cancer (CRC); tumor microenvironment; chemotherapy resistance; inflammation-related signalling; biotherapeutics; immune response; cancer progression

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

Natural Products and Their Derivatives as Antitumor Agents

edited by

Branislav Nastasijevic

submission deadline 30 Apr 2026 | Viewed by 25 | Submission Open

Keywords: anticancer drug screening; derivatives of natural compounds; targeted cancer therapy; multi-target therapy; cancer drug resistance; drug repurposing; anticancer drug bioavailability; antiproliferative activity; natural products as radiosensitizers; natural products as radioprotectors; natural remedies for chemotherapy side effects

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

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