Nod-Like Receptors
A special issue of Cells (ISSN 2073-4409).
Deadline for manuscript submissions: closed (16 July 2023) | Viewed by 375
Special Issue Editors
Interests: mechanism of inflammasome activation; small animal clinical pathology; inhibitors
Interests: inflammation; inflammasome; macrophages; Deubiquitinases; P2X7R; danger signals
Special Issue Information
Dear Colleagues,
Nod-like receptors (NLRs) form a family of intracellular pattern recognition receptors (PRRs) that were first described about 20 years ago. They are dedicated to sensing pathogens and pathogen-associated molecular patterns (PAMPs) in the cytoplasm. The biological functions of NLRs are diverse; they can form inflammasome complexes, activate NF-kB and MAPK pathways, and regulate inflammatory signaling pathways and pyroptosis. Although the role of different NLR proteins in diverse microbial infections has been extensively studied, the critical role of NLRs in inflammatory and autoimmune diseases is still significant.
This Special Issue aims to enhance the current knowledge of any aspect of the function, activation and regulation of Nod-like receptors with original research articles, and to summarize the current state of this complex field with compelling reviews. We welcome the submission of reviews and original research articles focusing on the molecular mechanisms of the NLR-mediated regulation of immune responses and cell signaling pathways.
Dr. Fushan Shi
Dr. Gloria Lopez-Castejon
Guest Editors
Manuscript Submission Information
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