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Cancers publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Personalized Cancer Therapy: Strategies for Overcoming On-Target and Bypass Resistance

edited by

Valentina Foglizzo

submission deadline 31 Jan 2026 | Viewed by 91 | Submission Open

Keywords: resistance mechanisms; biomarker; oncogene dependency; target therapy; personalized therapy

(This special issue belongs to the Section Molecular Cancer Biology)

Advances in Thoracic Oncology Research

edited by

Domenico Galetta

submission deadline 1 Feb 2026 | 1 articles | Viewed by 2884 | Submission Open

Keywords: lung cancer; mediastinal; thymic; neuroendocrine; robotic; VATS; chest wall; chemotherapy; immunotherapy; radiotherapy

(This special issue belongs to the Section Cancer Therapy)

Therapy for HER2 Breast Cancer

edited by

Junji Tsurutani

and Sandra M. Swain

submission deadline 1 Feb 2026 | Viewed by 136 | Submission Open

Keywords: antibody– drug conjugate; trastuzumab; pertuzumab; tyrosine kinase inhibitor; trastuzumab deruxtecan

(This special issue belongs to the Section Cancer Therapy)

Cancer Immunotherapy in Clinical and Translational Research

edited by Sofia Genta

submission deadline 10 Feb 2026 | 7 articles | Viewed by 29271 | Submission Open

Keywords: cancer immunotherapy; clinical research; immune checkpoint inhibitor; cancer vaccines; biomarker; translational research

(This special issue belongs to the Section Cancer Immunology and Immunotherapy)

New Insights into Prostate Cancer Radiotherapy

edited by

Grace Lu-Yao

submission deadline 10 Feb 2026 | 6 articles | Viewed by 14773 | Submission Open

Keywords: prostate cancer; radiotherapy; radiation therapy

(This special issue belongs to the Section Cancer Therapy)

New Insights into Cancer Radiotherapy

edited by

Michael L. F. Lerch

submission deadline 10 Feb 2026 | 2 articles | Viewed by 2516 | Submission Open

Keywords: radiotherapy; X-rays; gamma rays; external beam radiation therapy; brachytherapy; palliative care; intensity-modulated radiotherapy (IMRT); stereotactic body radiotherapy (SBRT); proton therapy

(This special issue belongs to the Section Cancer Therapy)

Recent Developments in the Field of Radiotherapy Treatment for Lung Cancer

edited by Ioannis C. Maroulis

submission deadline 10 Feb 2026 | 1 articles | Viewed by 1750 | Submission Open

Keywords: lung cancer; radiotherapy; non-small-cell lung cancer (NSCLC)

(This special issue belongs to the Section Cancer Therapy)

Transforming Liver Cancer Care: From Molecular Understanding to Novel Therapeutic Strategies

edited by

Chencheng Xie

submission deadline 10 Feb 2026 | 1 articles | Viewed by 945 | Submission Open

Keywords: liver cancer; molecular research; biomarkers; targeted therapy; translational research

(This special issue belongs to the Section Tumor Microenvironment)

Advances in Surgical Treatment of Gynecological Cancers

edited by

Denis Querleu

, Joanna P. Kacperczyk-Bartnik and

Aleksandra Strojna

submission deadline 14 Feb 2026 | 2 articles | Viewed by 2847 | Submission Open

Keywords: gynecological oncology; image-guided surgery; lymphadenectomy; minimally invasive surgery; ovarian cancer surgery; patient outcomes; perioperative care; precision surgery; radical hysterectomy; robotic-assisted surgery; surgical oncology

(This special issue belongs to the Section Cancer Therapy)

Metronomic Chemotherapy in Female Cancers

edited by

Luca Roncati

submission deadline 14 Feb 2026 | 1 articles | Viewed by 1833 | Submission Open

Keywords: metronomic chemotherapy; female cancers; anti-tumor mechanisms; clinical trials and outcomes; combination therapies

(This special issue belongs to the Section Cancer Therapy)

New and Emerging Strategies for Targeting Genomic Instability and Overcoming Drug Resistance in Lung Cancer

edited by Kelsie L. Thu

submission deadline 15 Feb 2026 | 5 articles | Viewed by 17474 | Submission Open

Keywords: lung cancer; genomic instability; drug resistance; treatment strategy; targeted therapy

(This special issue belongs to the Section Cancer Therapy)

New Strategies in Diagnosis and Treatments for Brain Tumors: 2nd Edition

edited by Sven Rainer Kantelhardt

submission deadline 15 Feb 2026 | 4 articles | Viewed by 16266 | Submission Open

Keywords: glioma; brain tumor; molecular guided therapy; personal medicine; radiomics; digital analysis; artificial intelligence; intraoperative imaging; surgical resection

(This special issue belongs to the Section Cancer Therapy)

Advances in Esophageal Cancer

edited by Sacheen Kumar

submission deadline 15 Feb 2026 | 4 articles | Viewed by 8044 | Submission Open

Keywords: esophageal adenocarcinoma; esophageal squamous cell carcinoma; long-term survival; biomarkers; disease surveillance; treatment response

(This special issue belongs to the Section Cancer Therapy)

Neoadjuvant Therapy in Hepatopancreatobiliary Malignancies: Current Trends and Future Directions

edited by

Daniela Cornelia Lazăr

submission deadline 15 Feb 2026 | 1 articles | Viewed by 2581 | Submission Open

Keywords: neoadjuvant therapy; hepatopancreatobiliary malignancies; hepatocellular carcinoma; pancreatic cancer; cholangiocarcinoma; chemotherapy; radiotherapy; immunotherapy; targeted therapies; personalized treatment

(This special issue belongs to the Section Cancer Therapy)

Oligometastases Hypothesis to Advancing New Perspectives on Cancer: Oligo-Reurrence

edited by

Yuzuru Niibe

Dai Sonoda

and

Tadahiko Shien

submission deadline 15 Feb 2026 | 1 articles | Viewed by 2301 | Submission Open

Keywords: oligometastases; oligo-recurrence; sync-oligometastases

(This special issue belongs to the Section Cancer Metastasis)

The Elderly Multiple Myeloma Patient in the Era of Quad Therapy and CAR-T Cells

edited by James J. Ignatz-Hoover and Koen Van Besien

submission deadline 15 Feb 2026 | 1 articles | Viewed by 1716 | Submission Open

Keywords: multiple myeloma; quad therapy; CAR-T; elderly

(This special issue belongs to the Section Cancer Therapy)

Advances in Precision Medicine: Targeting Known and Emerging Oncogenic Targets in Lung Cancer (2nd Edition)

edited by

Tianhong Li

submission deadline 15 Feb 2026 | Viewed by 209 | Submission Open

Keywords: precision oncology; lung cancer; oncogenic target; targeted therapy; biomarker; diagnosis

(This special issue belongs to the Section Molecular Cancer Biology)

Epigenetics and Non-Coding RNAs in Multiple Myeloma

edited by

Rui Bergantim

submission deadline 15 Feb 2026 | Viewed by 145 | Submission Open

Keywords: multiple myeloma; epigenetics; non-coding RNAs; microRNAs (miRNAs); long non-coding RNAs (lncRNAs); circular RNAs (circRNAs); DNA methylation; histone modifications; drug resistance; precision medicine

(This special issue belongs to the Section Cancer Biomarkers)

Genetic Changes in CNS Neoplasms

edited by Kimberly Bojanowski Hoang

submission deadline 15 Feb 2026 | Viewed by 106 | Submission Open

Keywords: primary brain tumor; secondary brain tumor; metastasis; glioma; genetics; genomics; CNS; neoplasms

(This special issue belongs to the Section Cancer Biomarkers)

Prognostic and Predictive Biomarkers in Ovarian Cancer

edited by Jayakumar Nair

submission deadline 15 Feb 2026 | Viewed by 43 | Submission Open

Keywords: molecular biomarkers; clinical biomarkers; immune biomarkers; genetic biomarkers; ovarian cancer; personalized medicine

(This special issue belongs to the Section Cancer Biomarkers)

Diagnosis, Treatment and Prevention of Gastrointestinal Cancer (2nd Edition)

edited by

Anna Kakehashi

and Min Gi

submission deadline 18 Feb 2026 | 2 articles | Viewed by 10635 | Submission Open

Keywords: cancer; screening; diagnosis; anti-cancer; drugs; mechanisms of carcinogenesis; chemopreventive agents

(This special issue belongs to the Section Cancer Therapy)

Epigenetic Regulation in Cancers

edited by

Sudhir Rai

and

Seema Kumari

submission deadline 20 Feb 2026 | 3 articles | Viewed by 11518 | Submission Open

Keywords: oncogenes; tumor suppressor genes; tumor microenvironment; cancer therapy; DNA and histone methylation; microRNAs; epitranscriptomics; RNA modifications; modifying proteins

(This special issue belongs to the Section Tumor Microenvironment)

Gaps in Cancer Cachexia Research

edited by Jose M. Garcia and

Lindsey J. Anderson

submission deadline 20 Feb 2026 | 3 articles | Viewed by 11177 | Submission Open

Keywords: cancer cachexia; physical function; innovative models; rehabilitation; patient-reported outcomes; gender; aging; skeletal muscle; brain; adipose tissue

(This special issue belongs to the Section Cancer Survivorship and Quality of Life)

Quality of Life and Side Effects Management in Cancer Treatment (3rd Edition)

edited by

António Araújo

submission deadline 20 Feb 2026 | 4 articles | Viewed by 9489 | Submission Open

Keywords: cancer treatment adverse events; quality of life in cancer patients; chemotherapy adverse events; target therapy adverse events; immunotherapy adverse events; hormonotherapy adverse events; chemotherapy-induced nausea and vomiting; cancer pain

(This special issue belongs to the Section Cancer Survivorship and Quality of Life)

Chronic Intestinal Inflammation and Cancers (2nd Edition)

edited by Livia Biancone and David Laharie

submission deadline 20 Feb 2026 | 3 articles | Viewed by 5829 | Submission Open

Keywords: colorectal cancer; chronic inflammation; inflammatory bowel disease; inflammation-associated dysplasia; outcomes; cancer molecular pathways

(This special issue belongs to the Section Cancer Epidemiology and Prevention)

Ultrasonography for Pancreatobiliary Cancer

edited by

Yasunobu Yamashita

submission deadline 20 Feb 2026 | 3 articles | Viewed by 5474 | Submission Open

Keywords: endoscopic ultrasonography; abdominal ultrasonography; early diagnosis project; screening; EUS-FNA; interventional EUS; enhancement EUS; EUS-RFA

(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)

Multiple Myeloma: Recent Advances in Diagnosis, Analysis and Therapeutic Management: 2nd Edition

edited by

Juan Manuel Rosa-Rosa

submission deadline 20 Feb 2026 | 1 articles | Viewed by 3518 | Submission Open

Keywords: multiple myeloma (MM); hematologic malignancies; next-generation sequencing; heterogeneous disease; tumor heterogeneity; genomic landscape; outcomes; novel treatments; clinical trial

(This special issue belongs to the Section Cancer Therapy)

Breast Cancer Biomarkers and Clinical Translation: 2nd Edition

edited by

Cristian Scatena

and Carmine De Angelis

submission deadline 20 Feb 2026 | 3 articles | Viewed by 2577 | Submission Open

Keywords: breast cancer diagnosis; cancer risk; cell reprogramming; biomarkers; resistance; precision therapy

(This special issue belongs to the Section Cancer Biomarkers)

Advanced Surgical Modalities in Breast Cancer Treatment

edited by Jan Žatecký

submission deadline 20 Feb 2026 | 2 articles | Viewed by 1603 | Submission Open

Keywords: breast cancer surgery; breast cancer localization; breast conserving surgery; mastectomy; oncoplastic surgery; axillary lymph node staging; sentinel lymph node biopsy; targeted axillary dissection

(This special issue belongs to the Section Clinical Research of Cancer)

Fibroblasts as Playmakers of Cancer Progression: Current Knowledge and Future Perspectives (2nd Edition)

edited by

Kenichiro Ishii

submission deadline 20 Feb 2026 | Viewed by 282 | Submission Open

Keywords: tumor microenvironment; reactive stroma; fibroblasts; cancer progression; heterotypic interactions between cancer cells and fibroblasts; reactive stroma-targeted therapy

(This special issue belongs to the Section Molecular Cancer Biology)

AI-Driven Predictive Modeling in Radiation Therapy: Toward Precision and Personalized Clinical Applications

edited by

Yujie Huang

submission deadline 20 Feb 2026 | Viewed by 265 | Submission Open

Keywords: AI-based radiotherapy; predictive modeling in oncology; personalized radiation therapy; radiomics and dosiomics; adaptive radiotherapy; treatment outcome prediction; explainable AI in medicine; multimodal data integration; clinical decision support systems; precision cancer treatment

Molecular Tumor Boards: Promise and Limitations for Personalized Cancer Therapy: 2nd Edition

edited by

Claudia Paret

submission deadline 20 Feb 2026 | Viewed by 213 | Submission Open

Keywords: targeted therapy; drug repositioning; biomarkers; basket trials; precision oncology; personalized medicine

(This special issue belongs to the Section Molecular Cancer Biology)

Cancer and Aging: Challenges in Geriatric Cancer Survivorship

edited by

Ruth Parks

and Dana E. Giza

submission deadline 20 Feb 2026 | Viewed by 93 | Submission Open

Keywords: geriatric oncology; survivorship; advance care planning; quality of life; de-escalation of treatment

(This special issue belongs to the Section Cancer Survivorship and Quality of Life)

Minimal Residual Disease in Solid Tumors: Emerging Technologies and Clinical Applications

edited by

Sofia Agelaki

Kleita Michaelidou

and Aristeidis Boukouris

submission deadline 25 Feb 2026 | Viewed by 218 | Submission Open

Keywords: minimal residual disease (MRD); solid tumors; circulating tumor DNA (ctDNA); liquid biopsy; tumor-informed assays; precision oncology

(This special issue belongs to the Section Cancer Biomarkers)

Radiation Therapy for Modern Management of Bone Metastases (2nd Edition)

edited by

Francesco Cellini

submission deadline 25 Feb 2026 | Viewed by 190 | Submission Open

Keywords: radiotherapy; palliative care; steretactic radiotherapy; SBRT; immunotherapy; chemotherapy; oligometastases

(This special issue belongs to the Section Cancer Therapy)

Harnessing the Gut Microbiome to Improve Colorectal Cancer Outcomes

edited by Carole S. Richard

submission deadline 25 Feb 2026 | Viewed by 151 | Submission Open

Keywords: colorectal cancer (CRC); gut microbiome; screening; CRC cells; the gut microenvironment; oncological outcomes

(This special issue belongs to the Section Infectious Agents and Cancer)

Understanding HTLV-1 Induced Cancer: From Molecular Pathways to Treatment Strategies

edited by

George Eric Blair

and Suchitra Mohanty

submission deadline 25 Feb 2026 | Viewed by 105 | Submission Open

Keywords: HTLV-1; adult T-cell leukemia/lymphoma (ATLL); tax protein; HBZ protein; epigenetic regulation; immune evasion; chronic inflammation; host– pathogen interactions; viral oncogenesis; translational research

(This special issue belongs to the Section Infectious Agents and Cancer)

Advances in the Treatment of Gastrointestinal (GI) Cancers

edited by

Yoshiyasu Kono

submission deadline 27 Feb 2026 | 1 articles | Viewed by 1276 | Submission Open

Keywords: gastrointestinal cancers; targeted therapy; immunotherapy; precision oncology; biomarkers; molecular mechanisms; tumor microenvironment; resistance to therapy; translational research; clinical trials

(This special issue belongs to the Section Cancer Therapy)

Clinical and Translational Updates in Renal Cell Carcinoma (2nd Edition)

edited by

Irbaz B Riaz

submission deadline 27 Feb 2026 | Viewed by 140 | Submission Open

Keywords: renal cell carcinoma; RCC; machine cearning; clinical; translational developments

(This special issue belongs to the Section Clinical Research of Cancer)

Application of Imaging in Breast Cancer

edited by

Yun-Chung Cheung

Yao Melissa Min-Szu

and Chung Wai-Shan

submission deadline 28 Feb 2026 | 6 articles | Viewed by 19095 | Submission Open

Keywords: breast cancer; mammography/tomosynthesis/contrast-enhanced mammography; sonography/contrast-enhanced sonography; magnetic resonance imaging; PET/CT; quantitative imaging; elastography; optical imaging; artificial intelligence; image-guided biopsy

(This special issue belongs to the Section Methods and Technologies Development)

Challenges and Opportunities for Novel Therapeutic Strategies in Pediatric Oncology

edited by

Jeong A Park

and

Jaume Mora

submission deadline 28 Feb 2026 | 7 articles | Viewed by 16708 | Submission Open

Keywords: antibody-drug conjugate; bispecific antibody; cancer predisposition; CAR T cell; immunotherapy; leukemia; monoclonal antibody; neuroblastoma; pediatric cancer; photoimmunotherapy; precision medicine; sarcoma; translational research; tyrosine kinase inhibitor

(This special issue belongs to the Section Cancer Therapy)

Advances in Bladder Preservation Approaches for Bladder Cancer (2nd Edition)

edited by

Jay J. Liao

and Todd A. Yezefski

submission deadline 28 Feb 2026 | 5 articles | Viewed by 14413 | Submission Open

Keywords: bladder cancer; bladder preservation; trimodality therapy; chemoradiation; immunotherapy; intravesical therapy; BCG refractory or unresponsive

(This special issue belongs to the Section Cancer Epidemiology and Prevention)

State of the Art and Novelties in Multidisciplinary Approach to Soft Tissue and Bone Sarcomas

edited by Ron Batash, Alberto Crimì, Moshe Schaffer and

Pietro Ruggieri

submission deadline 28 Feb 2026 | 7 articles | Viewed by 14290 | Submission Open

Keywords: soft tissue sarcoma; bone sarcoma; treatment; diagnosis; radiation therapy; chemotherapy

(This special issue belongs to the Section Cancer Therapy)

Advances in Oncological Imaging (2nd Edition)

edited by

Michaela Cellina

and

Maurizio Cè

submission deadline 28 Feb 2026 | 5 articles | Viewed by 9978 | Submission Open

Keywords: oncological imaging; radiomics; deep learning; machine learning; image reconstruction; artificial intelligence; outcome prediction; oncological treatment planning; advanced imaging; personalized medicine

(This special issue belongs to the Section Methods and Technologies Development)

Navigating the Landscape of Female Cancers: Recent Discoveries and Treatment Trends

edited by

Federica Martorana

and Giacomo Barchiesi

submission deadline 28 Feb 2026 | 3 articles | Viewed by 8793 | Submission Open

Keywords: female malignancies; breast cancer; gynecological cancer; ovarian cancer; endometrial cancer; cervical cancer

(This special issue belongs to the Section Cancer Therapy)

New Insights into General, Functional and Oncologic Urology

edited by Kajetan Juszczak and

Przemysław Adamczyk

submission deadline 28 Feb 2026 | 4 articles | Viewed by 8566 | Submission Open

Keywords: basic science; experimental models; urological cancer; management innovations; multidisciplinary approaches; treatment outcomes

(This special issue belongs to the Section Clinical Research of Cancer)

Improving Surgical Care for Patients with Hepatobiliary and Pancreatic Cancers

edited by Christopher B. Nahm and Kai M. Brown

submission deadline 28 Feb 2026 | 2 articles | Viewed by 8015 | Submission Open

Keywords: hepatobiliary; pancreatic; surgery; biomarkers; prognosis; treatment strategy

(This special issue belongs to the Section Cancer Therapy)

Regulators of Breast Cancer Metastasis

edited by

Terumi Kohwi-Shigematsu

and

Saori Furuta

submission deadline 28 Feb 2026 | 2 articles | Viewed by 6917 | Submission Open

Keywords: tumor progression regulators; metastasis; tumor microenvironment; biomarkers for recurrence; transcriptional regulation; chromatin structure; epigenetics; cancer metabolism; cancer immunity; microbiome

(This special issue belongs to the Section Cancer Metastasis)

Diagnosis, Staging, and Management for Gynecologic Oncology

edited by

Malgorzata Klimek

submission deadline 28 Feb 2026 | 1 articles | Viewed by 6193 | Submission Open

Keywords: gynecologic oncology; cancer biology; HPV infection; molecular risk factors; translational medicine; cancer staging systems; radiation therapy; brachytherapy; radioresistance

(This special issue belongs to the Section Cancer Therapy)

Cervical Cancer: Clinical Feature, Trial and Management

edited by

Roberto Tozzi

Marco Noventa

and Carlo Saccardi

submission deadline 28 Feb 2026 | 2 articles | Viewed by 5972 | Submission Open

Keywords: cervical cancer; diagnosis; minimally invasive surgery; laparoscopy; locally advanced disease; management; treatment; adjuvant chemotherapy; immunotherapy

(This special issue belongs to the Section Cancer Therapy)

Displaying special issue 251-300 on page 6 of 24.

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