Sensors for the Detection of Biomarkers

Dear Colleagues,

According to the Biomarker Working Group, a biological marker (i.e., biomarker) is “a characteristic that is objectively measured and evaluated as an indicator of normal biological processes, pathogenic processes, or pharmacologic responses to a therapeutic intervention.”

In medicine, biomarkers can be used to: i) establish the susceptibility of an individual for developing a medical condition (risk biomarker); ii) detect the presence/absence of a disease (diagnostic biomarker); iii) identify the likelihood of a clinical event, disease recurrence or progression in patients who already have a condition of medical interest (prognostic biomarker); iv) monitor the status of a medical condition or for evidence of exposure to drugs or environmental agent (monitoring biomarker).

The benefit of using a biomarker for a specific purpose is directly related both to its appropriate application and to the quality of its quantification. Biosensor development for clinical purposes has attracted scientific interest over the past 20 years owing to the need for rapid, simple handheld testing devices in medicine. Indeed, biosensors associated to nanotechnologies allow the detection of analytes even in a small quantity of biological samples, such as a blood drops, and in alternative matrices such as saliva or sweat. Although there have been many advancements in the biosensors area, there is still a need to develop sensitive, fast, and accurate biosensors.

In this Special issue, we welcome all research and development that advance biosensor technologies and their application for the quantification of biomarkers relevant in the medical fields.

Dr. Maria Franzini
Guest Editor

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