Special Issue "Chiral Sensing Triggered by Plasmonic Metals"

A special issue of Biosensors (ISSN 2079-6374). This special issue belongs to the section "Optical and Photonic Biosensors".

Deadline for manuscript submissions: closed (25 February 2023) | Viewed by 151

Special Issue Editors

College of Chemistry and Materials Science, Shanghai Normal University, Shanghai 200234, China
Interests: Raman spectral electrochemistry; chemical imaging; chemical sensors and biosensors; SERS-probes for POCT applications
Special Issues, Collections and Topics in MDPI journals
College of Chemistry and Materials Science, Shanghai Normal University, Shanghai 200234, China
Interests: chiral inorganic nanomaterials; surface-enhanced Raman scattering; chiroptical analysis; chiral discrimination
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Molecular chirality plays a key role in determining the functions of biomolecules, pharmaceuticals and agrochemicals. Thus, chirality detection capable of distinguishing enantiomers and quantifying trace concentrations of chiral molecules is urgently needed. Conventional chiral analysis tools, including circular dichroism (CD), Raman optical activity (ROA), chromatography and nuclear magnetic resonance (NMR), still suffer some drawbacks, such as low sensitivity, high equipment costs and inefficiency in on site and in vivo analysis.

Due to their unique surface plasmonic resonance properties, plasmonic metals are able to tailor the absorptivity, scattering and fluorescence of molecules, which enables the development of detection methods with high sensitivity. In particular, chirality and chiroptical effects in plasmonic nano-/microstructures have gained increasing attention in recent years, as they can overcome the shortcomings of traditional chiroptical spectroscopies. For example, with the assistance of plasmonic nanomaterials and metamaterials, chiral light–matter interactions can be enhanced to amplify CD and ROA signals (referred to as surface-enhanced circular dichroism and Raman optical activity in some reports). In addition, metallic plasmonic nanostructures themselves can generate diverse CD signals in a spectral range from near-ultraviolet to near-infrared, and these signals are valuable for chiral detection as a supplement to molecular chiroptical signals.

Moreover, manipulation of the coupling between plasomonic materials and chiral molecules can result in strong enantiomer-selective optical or electrochemical responses, allowing chiral sensing to be performed even with nontraditional chiral analysis tools, including Raman spectroscopy, surface-enhanced Raman spectroscopy, colorimetric assay, fluorescence spectroscopy and electrochemical analysis. Consequently, novel chiral sensors are anticipated to surpass the capabilities of conventional chiral analysis strategies, enabling trace determination, bio-imaging and portable / real-time detection of various chiral molecules.

Accompanying these recent advances in artificial chiral plasmonic nanostructures, plasmonics-triggered chiral sensing represents an exciting field for potential breakthroughs in analytical science and technologies. Therefore, this Special Issue will highlight and present an overview of different aspects of plasmonic-metal-

assisted chiral detection, from the design and fabrication of plasmonic metallic materials/devices with promising potential in chiral biomarker and pesticide detection/ cosmetics residues to enantioselectivity mechanisms in matter–matter or light–matter interactions associated with chemical reactions, behaviors of cells and nanobio interfaces.

Reviews, full-length experimental or theoretical papers and short communications, comments and other types of papers will all be considered.

Prof. Dr. Haifeng Yang
Dr. Xinling Liu
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biosensors is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • chiral sensors
  • plasmonic metals
  • circular dichroism
  • Raman spectroscopy
  • surface enhanced Raman spectroscopy
  • colorimetric assay
  • electrochemical sensors

Published Papers

There is no accepted submissions to this special issue at this moment.
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