The Role of microRNAs in the Generation and Repair of Articular Cartilage
A special issue of Biology (ISSN 2079-7737).
Deadline for manuscript submissions: closed (30 December 2021) | Viewed by 296
Special Issue Editors
2. Department of Molecular Medicine, Institute of Basic Medical Sciences, University of Oslo, Domus Medica, Gaustad, Sognsvannsveien 9, 2. etg. 0372 OSLO, Norway
Interests: tissue engineering; cell therapy; cartilage; osteoarthritis; microRNA; stem cells
Interests: microRNA; cartilage; inflammation; osteoarthritis; stem cells; genome engineering; gene therapy; cell therapy
Special Issue Information
Dear Colleagues,
MicroRNAs are small double-stranded RNA molecules that have gained considerable interest during the past two decades because they regulate gene expression. MicroRNAs are now known to be involved in most, if not all, biological processes. Consequently, therapeutic overexpression or inhibition of microRNAs will change the fate of cells and may potentially improve disease outcomes. MicroRNAs may also play a role as disease biomarkers.
Damage to articular cartilage is the most common cause of musculoskeletal diseases. MicroRNAs clearly play an important role in these disorders, as demonstrated by the increasing numbers of articles publishing on the role of microRNAs in cartilage repair and cartilage biology. Still, there is a lot to learn, and with the discovery of variants of microRNAs, called isomiRs, the role of microRNAs in the generation and repair of articular cartilage remains a hot research field.
This Special Issue welcomes the submission of original articles and reviews that cover all aspects of the role played by microRNAs in the generation and repair of articular cartilage.
Dr. Jan E. Brinchmann
Dr. Tommy A. Karlsen
Guest Editors
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Keywords
- microRNA
- Articular cartilage
- Cartilage generation
- Cartilage repair
- Inflammation
- Osteoarthritis
- Gene Therapy.
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