Special Issue "Visions of the Hereafter: Consequences of Inflammation for Pathogen and Host 2.0"
Deadline for manuscript submissions: 28 February 2023 | Viewed by 408
2. St. Elisabeth Hospital, Tilburg, The Netherlands
Interests: mucosal immunology; immunoregulation (in autoimmune diseases, allergic diseases and infections); interaction between gut microbiota and the immune system; vaccination
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Upon infection of the (human) host, the invading microorganism will initially expand and proliferate. An immunocompetent host will generate an innate as well as an acquired, specific response, ultimately leading to the elimination of the microorganism. A (theoretical) digital outcome is that either the host will die, or the microorganism will. In real life, many intermediate situations will occur as a result. For further improvement of preventive and therapeutic measures of infectious diseases, it is important to have a more complete understanding (i.e., a vision) of both microbial pathogenesis as well as host immune defenses and the ultimate outcome (the hereafter).
Visions of the Hereafter is a painting by Jheronimus Bosch, and it consists of four different panels, two of them visualizing heaven and two hell. Survivors from infection are depicted as being in heaven, and the panels on hell illustrate a vivid picture of the fate of the destructive forces initiated by the inflammasome and the killing the microorganism.
In this Special Issue, contributors are encouraged to address the biological and clinical aspects of infection and inflammation, focusing on outcomes for the host as well as the pathogen. The host may be human, or any other representatives of the animal or plant kingdom. The Special Issue welcomes original research papers as well as reviews and opinion papers. A special clinical case can also be included. The Special Issue thus will provide a vision of the processes taking place during an infection, and information on how it is handled by the host, including the resolution of the infection and thereafter.
Prof. Dr. Ger Rijkers
Manuscript Submission Information
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