Special Issues

Bioengineering publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Bioengineering Approaches in Lung Injury and Repair submission deadline 28 Feb 2026 | Viewed by 138 | Submission Open
Keywords: bioengineering; lung injury; repair mechanisms; stem cell therapy; biomaterials
(This special issue belongs to the Section Regenerative Engineering)
Wearable Sensors and Robotic-Assisted Technologies for Activity Assistance and Gait Rehabilitation
edited by and Xiaoling Hu
submission deadline 28 Feb 2026 | Viewed by 131 | Submission Open
Keywords: wearable sensors; robotic-assisted technology; activity assistance; gait rehabilitation; balance; movement impairment; exoskeleton robot
(This special issue belongs to the Section Biosignal Processing)
Biofabrication of Biologically Realistic Constructs: Needs, Challenges, and Opportunities
edited by Nicanor Ilie Moldovan
submission deadline 28 Feb 2026 | Viewed by 125 | Submission Open
Keywords: biofabrication; biological realism; bioprinting; cell– biomaterial interaction; tissue engineering; hybrid constructs; clinical translation; in vitro models
(This special issue belongs to the Section Nanobiotechnology and Biofabrication)
Multiscale Mechanics of Biomaterials
edited by Pengfei Dong, and Yi Hua
submission deadline 28 Feb 2026 | Viewed by 117 | Submission Open
Keywords: multiscale mechanics; atomic force microscopy; machine learning; biomaterials; finite element method
(This special issue belongs to the Section Biomedical Engineering and Biomaterials)
Advanced Technologies for Orthopedic Repair and Regeneration
edited by Adriano Braile, and Giuseppe Toro
submission deadline 28 Feb 2026 | Viewed by 112 | Submission Open
Keywords: orthopedic regeneration; 3D printing; bioactive materials; mesenchymal stem cells; smart biomaterials; tissue engineering; predictive modeling; immunoengineering; antimicrobial strategies; personalized implants
(This special issue belongs to the Section Regenerative Engineering)
Stem Cell Culture and Development of Tissue Engineered Models
edited by
submission deadline 28 Feb 2026 | Viewed by 107 | Submission Open
Keywords: stem cell culture; tissue engineering; organoids; biomaterials; 3D cell culture; regenerative medicine; disease modeling; organ-on-a-chip
(This special issue belongs to the Section Regenerative Engineering)
Multimodal AI‑Assisted Bioprinting: From Material Selection to Automated Fabrication
edited by Ewa Stodolak-Zych, and Kamila Rawojć
submission deadline 28 Feb 2026 | Viewed by 104 | Submission Open
Keywords: 3D bioprinting; artificial intelligence; machine learning; bioink design; tissue engineering; multimodal data; closed-loop fabrication; automated manufacturing
(This special issue belongs to the Section Nanobiotechnology and Biofabrication)
Bioinformatics for Cardiovascular Disease
edited by João P. Monteiro and Quanyi Zhao
submission deadline 28 Feb 2026 | Viewed by 95 | Submission Open
Keywords: bioinformatics; cardiovascular disease; single-cell RNA-seq; single-cell ATAC-seq; spatial profiling; genomics; machine learning; multi-omics integration; systems biology; cardiac modeling; precision medicine; big data; translational bioinformatics
(This special issue belongs to the Section Cellular and Molecular Bioengineering)
Big Data and Artificial Intelligence in Trauma Outcome Prediction
edited by Peter Fu Ming Hu, Shiming Yang and William Teeter
submission deadline 28 Feb 2026 | Viewed by 94 | Submission Open
Keywords: trauma triage; emergency medicine; clinical decision support; outcome prediction; precision medicine; artificial intelligence; natural language processing
(This special issue belongs to the Section Biosignal Processing)
Polymeric Biomaterials for Drug Delivery
edited by
submission deadline 28 Feb 2026 | Viewed by 68 | Submission Open
Keywords: biomaterials; polymeric nanoparticles; stimuli-responsive systems; biodegradable polymers; drug delivery; gene therapy; targeted delivery; controlled release
(This special issue belongs to the Section Nanobiotechnology and Biofabrication)
From 3D/4D Printing to Biofunctional Surfaces and Smart Implant Systems
edited by
submission deadline 28 Feb 2026 | Viewed by 67 | Submission Open
Keywords: 3D/4D printing; biofunctional surfaces; smart implants; additive manufacturing in biomedicine
(This special issue belongs to the Section Nanobiotechnology and Biofabrication)
Advances in Novel Remineralizing Materials: Innovations for Sustainable Oral and Biomedical Applications
edited by Robert Hill
submission deadline 28 Feb 2026 | Viewed by 59 | Submission Open
Keywords: dental materials; remineralization; bioactive glass; glass ionomer cements; calcium phosphate cements; nanotechnology; adhesion; sustainable dentistry; clinical performance; biomedical engineering
(This special issue belongs to the Section Nanobiotechnology and Biofabrication)
Advanced Cryopreservation and Innovative Rewarming Strategies for Cells, Tissues, Organs and Organisms submission deadline 10 Mar 2026 | Viewed by 128 | Submission Open
Keywords: cryopreservation; vitrification strategies; rewarming technologies; cryoprotective agents; fertility preservation; plant cryobiology; aquatic species conservation; astrobiology and extreme environments
(This special issue belongs to the Section Cellular and Molecular Bioengineering)
Machine Learning in Ultrasound Imaging
edited by Laura Brattain, Vivek Singh and Md Mostafa Kamal Sarker
submission deadline 15 Mar 2026 | Viewed by 260 | Submission Open
Keywords: computer-aided diagnosis; medical image analysis; image segmentation; procedural guidance; clinical decision support; elastography; contrast-enhanced ultrasound; point-of-care ultrasound (POCUS); multimodal imaging
(This special issue belongs to the Section Biosignal Processing)
MRI and Its Applications submission deadline 20 Mar 2026 | Viewed by 143 | Submission Open
Keywords: MRI; multiparametric MRI; cancer Imaging; tumor characterization; therapy monitoring; whole-body MRI; pediatric MRI; oncologic imaging; clinical MRI
(This special issue belongs to the Section Biosignal Processing)
Bioengineering the AAV System: Devices, Quantitative Measurement, and Predictive Models
edited by Karim Daliri and
submission deadline 20 Mar 2026 | Viewed by 45 | Submission Open
Keywords: adeno-associated virus (AAV) vectors; device-assisted delivery; microfluidics; quantitative measurement
(This special issue belongs to the Section Cellular and Molecular Bioengineering)
Bioengineering Strategies for Ophthalmic Diseases
edited by
submission deadline 31 Mar 2026 | 5 articles | Viewed by 8623 | Submission Open
Keywords: ophthalmic diseases; imaging technology; artificial intelligence; retinal regeneration; corneal implants; drug delivery
(This special issue belongs to the Section Biomedical Engineering and Biomaterials)
Applications of Computational Modeling in Biomedical Image and Signal Processing—2nd Edition
edited by Xuxin Chen and
submission deadline 31 Mar 2026 | 4 articles | Viewed by 7315 | Submission Open
Keywords: computational modeling; quantitative disease markers; medical image processing; image segmentation; biosignal testing; biosignal processes; feature selection; deep learning; computer-aided diagnosis; data standardization; synthetic data generation
(This special issue belongs to the Section Biosignal Processing)
Development of Bioelectrochemical Systems for Environmental Engineering
edited by
submission deadline 31 Mar 2026 | 3 articles | Viewed by 6710 | Submission Open
Keywords: bioelectrochemical systems; microbial fuel cells; bioelectrosynthesis; high-added value chemicals; environmental engineering
(This special issue belongs to the Section Biochemical Engineering)
Innovative Approaches: Harnessing Virtual Reality for Assessment and Rehabilitation in Stroke and Aging-Related Disorders
edited by Gauthier Everard and
submission deadline 31 Mar 2026 | 5 articles | Viewed by 6062 | Submission Open
Keywords: virtual reality; assessment; rehabilitation; stroke; neurorehabilitation; older adults; kinematics; cognition
(This special issue belongs to the Section Biosignal Processing)
Recent Advances in Genomics Research
edited by Chien-Wei (Masaki) Lin
submission deadline 31 Mar 2026 | 3 articles | Viewed by 4453 | Submission Open
Keywords: genomics data analysis; NGS; AI; machine learning; multi-omics integration; single-cell sequencing; precision medicine
(This special issue belongs to the Section Cellular and Molecular Bioengineering)
Biomaterials for the Repair and Regeneration of Musculoskeletal Tissue
edited by Christopher Bibbo
submission deadline 31 Mar 2026 | 2 articles | Viewed by 4106 | Submission Open
Keywords: musculoskeletal; soft tissue; bone; cartilage; nerve; regenerative medicine; reconstructive surgery
(This special issue belongs to the Section Regenerative Engineering)
Novel Imaging Techniques in Radiotherapy
edited by and Junwei Shi
submission deadline 31 Mar 2026 | 3 articles | Viewed by 3702 | Submission Open
Keywords: radiotherapy; imaging; tumor localization; treatment assessment; radiation toxicity
(This special issue belongs to the Section Biosignal Processing)
Wearable, Flexible, and Integrated Microfluidic-Based Biosensors for Point-of-Care Testing Applications
edited by Madhusudan B. Kulkarni
submission deadline 31 Mar 2026 | 1 articles | Viewed by 3576 | Submission Open
Keywords: biomedical electronic devices; health-monitoring wearables; implantable sensors; bioelectronic medicine; personalized healthcare
(This special issue belongs to the Section Biomedical Engineering and Biomaterials)
Microalgae Biotechnology and Microbiology: Prospects and Applications
edited by Dora Allegra Carbone and Michael Melkonian
submission deadline 31 Mar 2026 | 3 articles | Viewed by 3388 | Submission Open
Keywords: microalgae; bacteria; photobioreactor; bioengineering; biomass; wastewater; compounds
(This special issue belongs to the Section Biochemical Engineering)
Augmented Reality, Virtual Reality and Extended Reality Solutions for Biomedical Applications
edited by and Arrigo Palumbo
submission deadline 31 Mar 2026 | 3 articles | Viewed by 3378 | Submission Open
Keywords: augmented reality (AR); virtual reality (VR); extended reality (XR); biomedicine; human– robot interaction; technology in healthcare; medical imaging; surgical simulation; surgical navigation; robotic-assisted surgery; rehabilitation technology; neurological disorders’ treatment; pain management; personalized healthcare; artificial intelligence (AI) in medicine; human– computer interaction in healthcare; digital health technologies
(This special issue belongs to the Section Biosignal Processing)
Bioengineering and the Eye—3rd Edition submission deadline 31 Mar 2026 | 3 articles | Viewed by 2863 | Submission Open
Keywords: stem cell therapies; functional ocular tissue equivalents; biomaterials; 3D bioprinting; tissue engineering
(This special issue belongs to the Section Regenerative Engineering)
Challenges for Managing Glaucoma in the 21st Century
edited by
submission deadline 31 Mar 2026 | 2 articles | Viewed by 2785 | Submission Open
Keywords: retinal imaging; artificial intelligence; minimally invasive glaucoma surgeries (MIGSs); telemedicine; neuroimaging
(This special issue belongs to the Section Biomedical Engineering and Biomaterials)
Cardiovascular Models and Biomechanics submission deadline 31 Mar 2026 | 1 articles | Viewed by 2001 | Submission Open
Keywords: vascular mechanics; patient-specific modeling; cardiovascular devices; mechanobiology; experimental methods; computational modeling; machine learning
(This special issue belongs to the Section Biomedical Engineering and Biomaterials)
Artificial Intelligence and Wearable Biosensors for Precision Medicine: Integrating Technology
edited by
submission deadline 31 Mar 2026 | 2 articles | Viewed by 1949 | Submission Open
Keywords: healthcare; gynecology; pelvic floor medicine; pelvic floor rehabilitation; pelvic floor training; laparoscopy; pelvic organ prolapse; urinary incontinence; anal incontinence; overactive bladder; ultrasound; urodynamics; urogynecology; new technologies; pelvic pain; laser; radiofrequency; magnetic stimulation; functional electrical stimulation; biofeedback; vaginal rejuvenation; electronic bladder diaries; sacral neuromodulation; women’ s health
(This special issue belongs to the Section Biosignal Processing)
Applications of Artificial Intelligence for Medical Diagnosis
edited by Alessio Luschi and Pietro Rubegni
submission deadline 31 Mar 2026 | 2 articles | Viewed by 1511 | Submission Open
Keywords: healthcare; medicine; artificial intelligence; deep learning; machine learning; generative AI
(This special issue belongs to the Section Biosignal Processing)
Contribution of Bioprocess Engineering to the Achievement of the UN Sustainable Development Goals (SDGs)
edited by
submission deadline 31 Mar 2026 | 1 articles | Viewed by 1276 | Submission Open
Keywords: bioprocess engineering; sustainability; sustainable development goals (SDGs)
(This special issue belongs to the Section Biochemical Engineering)
Contemporary Trends and Future Perspectives in Orthodontic Treatment submission deadline 31 Mar 2026 | 1 articles | Viewed by 1249 | Submission Open
Keywords: orthodontic biomechanics; clear aligners; digital orthodontics; artificial intelligence; finite element analysis; interdisciplinary treatment; patient experience; long-term stability; innovative appliances; future trends in orthodontics
(This special issue belongs to the Section Biomedical Engineering and Biomaterials)
Recent Advances in Soft Tissue Characterization Using Optical Techniques
edited by Bin Yang, and Xu Feng
submission deadline 31 Mar 2026 | 1 articles | Viewed by 1220 | Submission Open
Keywords: optical elastography; spectroscopy; optical imaging; disease diagnostics; tissue optics; artificial intelligence
(This special issue belongs to the Section Biosignal Processing)
Nanobiosensors for Age-Related Diseases Diagnosis submission deadline 31 Mar 2026 | 1 articles | Viewed by 1184 | Submission Open
Keywords: nanobiosensors; nanomaterials; age-related diseases; wearable devices; implantable devices
(This special issue belongs to the Section Biosignal Processing)
Advances and Clinical Applications of Anterior Segment Imaging Techniques—2nd Edition
edited by
submission deadline 31 Mar 2026 | 1 articles | Viewed by 1078 | Submission Open
Keywords: anterior segment; cornea; cataract; conjunctiva; anterior segment imaging; refractive surgery
Advanced Dental Materials for Restorative Dentistry
edited by
submission deadline 31 Mar 2026 | 1 articles | Viewed by 1067 | Submission Open
Keywords: denal restoration; restorative dentistry; dental biomaterials
(This special issue belongs to the Section Biomedical Engineering and Biomaterials)
Stem Cell Immunoengineering
edited by Yun Chang
submission deadline 31 Mar 2026 | 1 articles | Viewed by 1034 | Submission Open
Keywords: stem cell; immunoengineering; immune cells; genetic and epigenetic programming; biomaterials; delivery system
(This special issue belongs to the Section Nanobiotechnology and Biofabrication)
AI-Driven Advances in Biomedical Diagnosis and Prognosis: Innovations, Applications, and Emerging Trends
edited by , Fayaz A. Ali Dharejo and
submission deadline 31 Mar 2026 | Viewed by 888 | Submission Open
Keywords: artificial intelligence; deep learning; biomedical imaging; biomedical sensing; disease diagnosis; disease prognosis; treatment monitoring; clinical decision-making
(This special issue belongs to the Section Biosignal Processing)
AI Advancements in Healthcare: Medical Imaging and Sensing Technologies, 2nd Edition
edited by and Kanghyun Ryu
submission deadline 31 Mar 2026 | 1 articles | Viewed by 878 | Submission Open
Keywords: biomedical imaging; biosignals; medical image analysis; abnormalities classification and detection; medical image segmentation; medical image reconstruction; medical image denoising; medical image registration; AI in biomedical systems; computer-aided diagnosis systems
(This special issue belongs to the Section Biosignal Processing)
Artificial Intelligence and Nanotechnology in Cancer Therapy
edited by Wancheng Guo and
submission deadline 31 Mar 2026 | Viewed by 656 | Submission Open
Keywords: AI; nanotechnology; cancer therapy
(This special issue belongs to the Section Nanobiotechnology and Biofabrication)
Bioengineering Cardiovascular Cell and Gene Therapies: Advances and Translational Challenges submission deadline 31 Mar 2026 | Viewed by 485 | Submission Open
Keywords: myocardial infarction; atherosclerosis; peripheral artery disease (PAD); stem cells differentiation; iPSCs disease modeling; biomaterials; gene delivery; tissue engineering approaches; vascular regeneration; cardiac repair; CRISPR gene editing; bio-scaffolds; bioprinting; microfluidics; organ-on-a-chip; immunomodulation; exosomes; drug delivery; clinical translation
(This special issue belongs to the Section Regenerative Engineering)
Technological Advances in Neurorehabilitation
edited by and Andria J. Farrens
submission deadline 31 Mar 2026 | Viewed by 382 | Submission Open
Keywords: assistive technology; neuroimaging; neurorehabilitation; robotics; wearables
(This special issue belongs to the Section Biomedical Engineering and Biomaterials)
Computational Intelligence for Healthcare
edited by , Chee Wei Tan and Qingpeng Zhang
submission deadline 31 Mar 2026 | Viewed by 358 | Submission Open
Keywords: artificial intelligence; big data analytics; generative models; pathogen tracking and tracing; chronic disease prediction and management; predictive modeling; bioinformatics; pandemic preparedness; IoT-enabled biosensors; health disparities and ethics; multi-modal data fusion
(This special issue belongs to the Section Biosignal Processing)
Multiscale Modeling in Computational Biomechanics: When Contemporary AI Meets Virtual Human Twin
edited by
submission deadline 31 Mar 2026 | Viewed by 331 | Submission Open
Keywords: multiscale modeling; computational biomechanics; AI-driven biomechanics; virtual human twin; generative AI in medicine
(This special issue belongs to the Section Biomechanics and Sports Medicine)
Strategies for Microbial Bioprocess Optimization
edited by
submission deadline 31 Mar 2026 | Viewed by 307 | Submission Open
Keywords: metabolic engineering; fermentation; synthetic biology; bioreactor design; synthetic microbial communities; machine learning based process design; renewable substrates; life cycle assessment
(This special issue belongs to the Section Biochemical Engineering)
Hot Melt Extrusion and 3D Printing for Enhanced Drug Delivery submission deadline 31 Mar 2026 | Viewed by 302 | Submission Open
Keywords: 3D printing in pharmaceutics; additive manufacturing in pharmaceuticals; biodegradable polymers; controlled drug release; devices for drug delivery; hot-melt extrusion (HME); implantable drug delivery systems; personalized medicine; regulatory aspects of 3D-printed dosage forms; solid dispersions
(This special issue belongs to the Section Nanobiotechnology and Biofabrication)
Bio-Applications of Engineered Escherichia coli—Second Volume submission deadline 31 Mar 2026 | Viewed by 250 | Submission Open
Keywords: Escherichia coli; heterologous production; biosynthetic pathways; value-added compounds; microbial chassis; microbial host; biosensors; whole-cell biosensors; diagnosis tools; therapeutic tools
(This special issue belongs to the Section Biochemical Engineering)
Machine Learning and Artificial Intelligence for Biostatistics
edited by Muktar Beshir Ahmed and
submission deadline 31 Mar 2026 | Viewed by 244 | Submission Open
Keywords: artificial intelligence; machine learning; biostatistics; medical image analysis; biosignal processing; bioinformatics; deep learning; biomedical data science; clinical prediction; statistical learning
(This special issue belongs to the Section Biosignal Processing)
Advanced Bioprocessing Approaches in Energy and Nutrient Recovery from Waste submission deadline 31 Mar 2026 | Viewed by 201 | Submission Open
Keywords: anaerobic digestion; biogas production; biogas upgrading; hydrothermal carbonization; thermochemical processes; microbial communities; manure management; wastewater treatment; nutrient recovery; energy recovery; computational modeling; machine learning; circular economy; methane yield; nitrogen recovery; phosphorus recovery
(This special issue belongs to the Section Biochemical Engineering)
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