Special Issues

Bioengineering publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Oral Wound Healing and Material Engineering
edited by
submission deadline 31 Dec 2025 | Viewed by 115 | Submission Open
Keywords: oral; healing; regeneration; mucosa; bone; biomaterial
(This special issue belongs to the Section Biomedical Engineering and Biomaterials)
Transformative Technologies for Bioengineering and Regenerative Medicine
edited by and Joshua Hunsberger
submission deadline 10 Jan 2026 | 1 articles | Viewed by 1891 | Submission Open
Keywords: regenerative medicine; tissue engineering; artificial intelligence; digital twins; IIoTs; biomaterials; biomanufacturing; cybersecurity
(This special issue belongs to the Section Regenerative Engineering)
Gene Delivery for Cancer Therapy
edited by Huiyi Liang and Tianqi Nie
submission deadline 10 Jan 2026 | Viewed by 266 | Submission Open
Keywords: gene delivery; drug delivery; nanoparticles; hydrogel; cancer
(This special issue belongs to the Section Nanobiotechnology and Biofabrication)
Electrical Impedance Tomography: New Advances in Biomedical Signal Processing
edited by Meng Dai
submission deadline 12 Jan 2026 | 2 articles | Viewed by 2962 | Submission Open
Keywords: electrical impedance tomography (EIT); signal processing; clinical noises; body movement; radiation-free imaging; image reconstruction; machine learning; artificial intelligence; real-time EIT; quantitative EIT
(This special issue belongs to the Section Biosignal Processing)
Development and Application of Extracellular Vesicles for Neurodegenerative Diseases
edited by Mangesh Dattu Hade
submission deadline 12 Jan 2026 | Viewed by 221 | Submission Open
Keywords: extracellular vesicles (EVs); neurodegenerative diseases; exosomes; blood– brain barrier; biomarkers; therapeutic nanocarriers
(This special issue belongs to the Section Regenerative Engineering)
Tumor Mechanobiology and Translational Insights
edited by
submission deadline 15 Jan 2026 | Viewed by 267 | Submission Open
Keywords: tumor mechanobiology; tumor microenvironment; mechanotransduction; ECM remodeling; tissue mechanics; translational mechanobiology
(This special issue belongs to the Section Cellular and Molecular Bioengineering)
Design and Synthesis of Functional Deuterated Biomaterials
edited by Nageshwar R. Yepuri
submission deadline 20 Jan 2026 | 3 articles | Viewed by 4671 | Submission Open
Keywords: deuterated lipids; deuterated phospholipids; lipid nano particle; lipid nano discs; deuterated fatty acids; deuterated amino acids
(This special issue belongs to the Section Biomedical Engineering and Biomaterials)
Engineering Stem Cells and Their Derivatives for Wound Healing and Tissue Regeneration
edited by Yueh Hsun Kevin Yang
submission deadline 25 Jan 2026 | Viewed by 80 | Submission Open
Keywords: stem cells; extracellular vesicles; biomaterials; immunoengineering; gene editing; regenerative medicine; wound healing
(This special issue belongs to the Section Regenerative Engineering)
New Sight for the Treatment of Dental Diseases: Updates and Direction submission deadline 31 Jan 2026 | 7 articles | Viewed by 40488 | Submission Open
(This special issue belongs to the Section Regenerative Engineering)
Medical Imaging Analysis: Current and Future Trends
edited by He Zhao and
submission deadline 31 Jan 2026 | 7 articles | Viewed by 10018 | Submission Open
Keywords: computer vision; artificial intelligence (AI); multi-modality learning; disease progression monitoring; explainable AI; human-computer interaction
(This special issue belongs to the Section Biosignal Processing)
Technological Advances for Gait and Balance Assessment
edited by Alessandro Zampogna, and
submission deadline 31 Jan 2026 | 5 articles | Viewed by 9330 | Submission Open
Keywords: novel diagnostic devices and wearable sensors; machine learning and artificial intelligence applications; biomechanical analysis; telemedicine and remote monitoring solutions
(This special issue belongs to the Section Biosignal Processing)
Dynamic Insights: Unveiling the Biomechanics of Sport Through Motion Analysis
edited by and Sang-Hoon Yeo
submission deadline 31 Jan 2026 | 5 articles | Viewed by 9152 | Submission Open
Keywords: artificial intelligence; augmented reality; biomechanics; E-sports; instrumentation; kinesiology; machine learning; motion analysis; performance enhancement; virtual reality; wearable technology
(This special issue belongs to the Section Biomechanics and Sports Medicine)
Advanced Technology for Implant Polymers in Orthopaedics, Spine, and Trauma
edited by Steven M. Kurtz, Hannah Spece, and
submission deadline 31 Jan 2026 | 4 articles | Viewed by 8418 | Submission Open
Keywords: UHMWPE; highly crosslinked UHMWPE; HXLPE; PEEK; PEKK; PAEK; additive manufacturing; AM; 3D printing
(This special issue belongs to the Section Biomedical Engineering and Biomaterials)
Innovative Bioengineering Paradigms for Cardiac Repair: Cell-Based and Cell-Free Approaches
edited by and Xingyu He
submission deadline 31 Jan 2026 | 3 articles | Viewed by 6214 | Submission Open
Keywords: cardiac regeneration; cardiac repair; stem cells; tissue engineering; cell transplant; gene delivery; extracellular vesicles; nanotechnology; immunomodulation; lineage reprogramming
(This special issue belongs to the Section Regenerative Engineering)
Disease Diagnosis and Therapy Using Viral Vectors submission deadline 31 Jan 2026 | 1 articles | Viewed by 5822 | Submission Open
Keywords: gene therapy; viral vectors; genetic disease
(This special issue belongs to the Section Cellular and Molecular Bioengineering)
Low-Back Pain: Assessment and Rehabilitation Research submission deadline 31 Jan 2026 | 2 articles | Viewed by 4501 | Submission Open
Keywords: chronic pain; wearable technologies; computational modeling; biomechanical analysis; assistive devices; sensor-based functional assessments
(This special issue belongs to the Section Biomedical Engineering and Biomaterials)
Bioengineering in a Generative AI World
edited by , Ulas Bagci and Yuxiang Zhou
submission deadline 31 Jan 2026 | 2 articles | Viewed by 4190 | Submission Open
Keywords: generative AI; bioengineering; machine learning; synthetic biology; drug discovery
(This special issue belongs to the Section Biosignal Processing)
Digital Technologies to Improve Diagnostic Cytopathology: Future Outlook
edited by
submission deadline 31 Jan 2026 | 1 articles | Viewed by 3552 | Submission Open
Keywords: machine learning; cytopathology; digital cytology; computer-aided diagnosis; virtual reality; natural language process
(This special issue belongs to the Section Biomedical Engineering and Biomaterials)
New Sights of Machine Learning and Digital Models in Biomedicine
edited by Hatem Alhadainy
submission deadline 31 Jan 2026 | 2 articles | Viewed by 2976 | Submission Open
Keywords: machine learning; biomedical imaging; predictive modeling; medical data analytics; genomics; precision medicine; bioinformatics; machine learning algorithms; computer-aided diagnosis; imaging analysis; clinical decision support; electronic health records (EHR); disease prediction simulation models; virtual patients; drug discovery; health informatics
(This special issue belongs to the Section Biosignal Processing)
Advances in Polyhydroxyalkanoate (PHA) Production, 5th Edition
edited by
submission deadline 31 Jan 2026 | 1 articles | Viewed by 2499 | Submission Open
Keywords: polyhydroxyalkanoate (PHA); biopolyesters; bioprocess design; sustainable development
(This special issue belongs to the Section Biochemical Engineering)
New Sights of Mathematical Modeling in Biomedicine: Updates and Direction
edited by
submission deadline 31 Jan 2026 | 1 articles | Viewed by 2496 | Submission Open
Keywords: mathematical modeling; machine learning; predictive modeling; data modeling; biological systems
(This special issue belongs to the Section Biosignal Processing)
Biomedical Engineering and Biomarkers in Plastic and Reconstructive Surgery Applications
edited by Saif Badran and Matthew Wood
submission deadline 31 Jan 2026 | 2 articles | Viewed by 2364 | Submission Open
Keywords: tissue engineering; 3D bioprinting; personalized medicine; metabolic biomarkers; regenerative medicine; advanced biomaterials
(This special issue belongs to the Section Biomedical Engineering and Biomaterials)
Data Modeling and Algorithms in Biomedical Applications submission deadline 31 Jan 2026 | 2 articles | Viewed by 2007 | Submission Open
Keywords: computer models; algorithms; biomedical applications; predictive modeling; machine learning; data analysis; data modeling; AI applications
(This special issue belongs to the Section Biosignal Processing)
Artificial Intelligence in Neurodegenerative Disorders: Advances in Diagnosis, Prognosis and Treatment
edited by Shayne Chau and Mohd. Farooq Shaikh
submission deadline 31 Jan 2026 | 1 articles | Viewed by 1900 | Submission Open
Keywords: artificial intelligence; neurodegenerative disorders; machine learning in neurology; diagnosis; treatment; prognosis
(This special issue belongs to the Section Biosignal Processing)
Printable Biomaterials from Tissue Engineering to Orthopedics: Fabrication, Mechanical Performance, and Biological Behavior submission deadline 31 Jan 2026 | 1 articles | Viewed by 1733 | Submission Open
Keywords: advanced printable biomaterials; biocompatibility; bioactivity; mechanical properties; physical and chemical properties
(This special issue belongs to the Section Biomedical Engineering and Biomaterials)
Recent Advances in Periodontal Tissue Engineering
edited by
submission deadline 31 Jan 2026 | 1 articles | Viewed by 1435 | Submission Open
Keywords: periodontal disease; periodontal tissue engineering; periodontal regeneration; biomaterials; soft and hard tissue regeneration
(This special issue belongs to the Section Regenerative Engineering)
Radiation Imaging and Therapy for Biomedical Engineering
edited by Bharat Guthikonda and Stanley Hoang
submission deadline 31 Jan 2026 | 1 articles | Viewed by 1176 | Submission Open
Keywords: radiation imaging; radiation therapy; biomedical engineering; diagnostic technologies; therapeutic innovations
(This special issue belongs to the Section Biomedical Engineering and Biomaterials)
Dental Pulp Stem Cells in Clinical Application: Present and Future Perspectives submission deadline 31 Jan 2026 | 1 articles | Viewed by 1095 | Submission Open
Keywords: dental pulp stem cells; cell injections; modified cells; cell sheets; cell spheroids; regeneration; damaged tissues; immunomodulation
(This special issue belongs to the Section Regenerative Engineering)
Advances in Spinal Biomechanics: Integrating In Vivo, In Vitro, and Computational Approaches in the Era of Evolving Spine Technologies
edited by
submission deadline 31 Jan 2026 | 1 articles | Viewed by 887 | Submission Open
Keywords: spinal biomechanics; computational modelling; spinal disorders; implants; finite element modeling
(This special issue belongs to the Section Biomedical Engineering and Biomaterials)
Recent Advances in Cardiothoracic Assist Devices
edited by Suvitesh Luthra and
submission deadline 31 Jan 2026 | 1 articles | Viewed by 801 | Submission Open
Keywords: mechanical circulatory support; VAD; OCS; LBE and EVLP; total artificial heart; heart failure; maglev and axial flow pumps; minimally invasive; wireless power; biocompatibility; AI in cardiac devices
(This special issue belongs to the Section Regenerative Engineering)
Metabolic MRI and Beyond: Emerging Technologies and Translational Biomedical Applications
edited by Kejia Cai and Mohan Jayatilake
submission deadline 31 Jan 2026 | 1 articles | Viewed by 798 | Submission Open
Keywords: metabolic MRI; CEST MRI; deuterium metabolic imaging; hyperpolarized 13C MRI; Arterial Spin Labeling (ASL); artificial intelligence in MRI; MR spectroscopy
(This special issue belongs to the Section Biosignal Processing)
Deep Learning for Medical Applications: Challenges and Opportunities
edited by , Robert Hudec and
submission deadline 31 Jan 2026 | Viewed by 517 | Submission Open
Keywords: deep neural networks; deep learning; machine learning; medical applications; healthcare AI; medical imaging; multimodal data integration; model interpretability
(This special issue belongs to the Section Biosignal Processing)
Emerging Artificial Intelligence Trends for Predictive Analytics and Personalized Healthcare submission deadline 31 Jan 2026 | Viewed by 425 | Submission Open
Keywords: artificial intelligence; machine learning; deep learning; predictive analytics; wearable sensors; medical devices; medical image analysis
(This special issue belongs to the Section Biosignal Processing)
Neuroimaging Techniques for Central Autonomic System: Methodologies and Applications
edited by Antonio Ferretti and Mauro Gianni Perrucci
submission deadline 31 Jan 2026 | Viewed by 395 | Submission Open
Keywords: integration of EEG; fMRI; fNIRS; or other neuroimaging modalities; fMRI preprocessing; autonomic system; central autonomic network; physiological noise; brainstem; epilepsy; sudep; valsalva maneuver; functional connectivity; integration of neuroimaging and extended-reality protocols
(This special issue belongs to the Section Biosignal Processing)
Dental Biomaterials: Current and Future Perspectives
edited by Sandro Basso Bitencourt, and Natalia Bastos-Bitencourt
submission deadline 31 Jan 2026 | Viewed by 329 | Submission Open
Keywords: dental materials; 3D printing; ceramics; CAD/CAM; bioactivity
(This special issue belongs to the Section Biomedical Engineering and Biomaterials)
New Sights of AI Tools and Deep Learning in Biomedicine submission deadline 31 Jan 2026 | Viewed by 326 | Submission Open
Keywords: artificial intelligence; machine learning; optimization; healthcare management; operation research; biomedicine
(This special issue belongs to the Section Biosignal Processing)
Robotics and Virtual Reality for Rehabilitation submission deadline 31 Jan 2026 | Viewed by 267 | Submission Open
Keywords: rehabilitation technology; wearable robotics; telerehabilitation; virtual reality; artificial intelligence; personalized therapy
(This special issue belongs to the Section Biomedical Engineering and Biomaterials)
Cardiac Digital Twins and AI: From Multi-Modal Modeling to Medical Implementation
edited by Lei Li, and Julia Camps
submission deadline 31 Jan 2026 | Viewed by 244 | Submission Open
Keywords: cardiac digital twins; multi-modal modeling; AI in cardiology; clinical translation; multi-modal data integration; personalized cardiac modeling; real-time simulation; cardiovascular precision medicine
(This special issue belongs to the Section Biosignal Processing)
Advances in Biomolecular Engineering for Regenerative Therapeutics
edited by , Paul Jordan Christo and
submission deadline 31 Jan 2026 | Viewed by 242 | Submission Open
Keywords: regenerative medicine; growth factors; gene therapy; exosomes; extracellular vesicles; proteomics; genomics; CRISPR; stem cells
(This special issue belongs to the Section Regenerative Engineering)
Advanced Data Processing for Wearable Neurophysiological Monitoring in Real-World Settings submission deadline 31 Jan 2026 | Viewed by 218 | Submission Open
Keywords: wearable neurophysiological signals; artifact removal; real-world monitoring; machine learning for biosignals; human factors; bioinformatics; bioengineering
(This special issue belongs to the Section Biosignal Processing)
Biofabrication Technologies: Novel Tools for More Effective Personalized Medicine and Regenerative Therapies
edited by , and Mauro Di Stasi
submission deadline 31 Jan 2026 | Viewed by 216 | Submission Open
Keywords: biodegradable polymers; biocompatible polymers; biomedical applications; biomaterials; renewable biomaterials; tissue engineering; regenerative medicine; biofabrication and bioprinting; personalized medicine; 3D tissue models
(This special issue belongs to the Section Regenerative Engineering)
Targeting Biofilm-Associated Infections: Mechanistic Insights, Challenges, and Therapeutic Innovations
edited by and Jianglong Yan
submission deadline 31 Jan 2026 | Viewed by 164 | Submission Open
Keywords: biofilm formation; antimicrobial resistance; biofilm disruption; bacterial infections; biomedical device-associated infections (BAIs); immunomodulatory biomaterials; antibacterial materials; antibacterial surface modification; photocatalytic disinfection; sonodynamic antibacterial therapy
(This special issue belongs to the Section Biomedical Engineering and Biomaterials)
Artificial Intelligence in Autoimmune Diseases submission deadline 31 Jan 2026 | Viewed by 158 | Submission Open
Keywords: artificial intelligence; autoimmune diseases; machine learning; personalized medicine; predictive analytics
(This special issue belongs to the Section Biosignal Processing)
Neuro-Bioengineering Innovations: Integrative Approaches for Diagnostics, Implants and Regenerative Therapies
edited by Frank D. Vrionis, , Yufei Tang and Mohsen Ahmadi
submission deadline 31 Jan 2026 | Viewed by 131 | Submission Open
Keywords: machine learning; artificial intelligence; spinal cord; neural interface technologies; implantable micro-devices; neuroimaging; explainable AI; finite element modeling; physics-informed neural networks (PINNs); bioinformatics; smart sensors; muscle modeling; biomechanics  
(This special issue belongs to the Section Biosignal Processing)
MRI Techniques for Disease Detection
edited by Christine Fernandez-Maloigne
submission deadline 31 Jan 2026 | Viewed by 127 | Submission Open
Keywords: MRI; disease detection; artificial intelligence; deep learning
(This special issue belongs to the Section Biosignal Processing)
Biomechanical Assessment in Rehabilitation and Performance submission deadline 31 Jan 2026 | Viewed by 126 | Submission Open
Keywords: motion capture analysis; postural control assessment; gait analysis; wearable sensor technologies; muscle activation studies; joint kinematics; sports injuries; sports therapy
(This special issue belongs to the Section Biomechanics and Sports Medicine)
Technologies for the Regeneration of Bone Tissue
edited by , , and Yanny Marliana Baba Ismail
submission deadline 31 Jan 2026 | Viewed by 115 | Submission Open
Keywords: bone tissue; regenerative medicine; immunomodulation; angiogenesis; growth factors; mechanical stimulation
(This special issue belongs to the Section Regenerative Engineering)
Intelligent Healthcare and Auditory Health: Machine Learning-Based Multimodal Biomedical Data Mining for Diagnosis
edited by and
submission deadline 31 Jan 2026 | Viewed by 115 | Submission Open
Keywords: computer-aided diagnosis; speech signal processing; auditory information processing; neurodegenerative diseases; wearable devices; health informatics; multimodal fusion; telemedicine; rehabilitation engineering; noise-robust algorithms; acoustic feature extraction; cognitive impairment screening; end-to-end speech enhancement  
(This special issue belongs to the Section Biosignal Processing)
Advancements in Drug Design and Delivery for Neuropsychological Disorders: Integrating Bioinformatics and Nanotechnology
edited by
submission deadline 31 Jan 2026 | Viewed by 107 | Submission Open
Keywords: neuropsychological disorders; drug design; drug delivery; bioinformatics; nanotechnology; computational drug design; targeted therapies; neuropharmacology; nanomedicine; bioengineering
(This special issue belongs to the Section Nanobiotechnology and Biofabrication)
Advanced Imaging Techniques for Neuroscience
edited by Dhairya A. Lakhani
submission deadline 31 Jan 2026 | Viewed by 106 | Submission Open
Keywords: machine learning; functional MRI (fMRI); resting-state fMRI; ultra-high-field MRI; connectomics; MR spectroscopy; molecular imaging; MR perfusion; high-grade glioma; ischemic stroke; vessel wall imaging; neurodegenerative disease; PET/MR
(This special issue belongs to the Section Biosignal Processing)
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