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Bioengineering publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Advanced Physical Techniques in Tissue Engineering and Regenerative Medicine

edited by

Alessandra Giuliani

Michele Furlani

and

Nicole Riberti

submission deadline 10 Dec 2025 | 1 articles | Viewed by 1649 | Submission Open

Keywords: tissue engineering; regenerative medicine; advanced imaging modalities; high-resolution microscopy; magnetic resonance imaging (MRI); computed tomography (CT); artificial intelligence (AI)

(This special issue belongs to the Section Regenerative Engineering)

Machine Learning-Aided Medical Image Analysis

edited by

Amirreza Mahbod

and Ramona Woitek

submission deadline 15 Dec 2025 | 4 articles | Viewed by 6342 | Submission Open

Keywords: artificial intelligence; deep learning; machine learning; medical image analysis; medical imaging

(This special issue belongs to the Section Biosignal Processing)

Retinal Biomarkers: Seeing Diseases in the Eye

edited by

Paul Constable

and

Hugo F. Posada-Quintero

submission deadline 15 Dec 2025 | 1 articles | Viewed by 1961 | Submission Open

Keywords: biomarker; retina; structure; function; machine learning; deep learning; classification; imaging; electrophysiology

(This special issue belongs to the Section Biosignal Processing)

Tissue Engineering for Regenerative Dentistry, 2nd Edition

edited by

Carlos Fernando Mourão

submission deadline 15 Dec 2025 | 1 articles | Viewed by 148 | Submission Open

Keywords: regenerative dentistry; autologous blood concentrates; platelet-rich fibrin (PRT); stem cells; bioactive biomaterials; tissue engineering; oral and maxillofacial regeneration; extracellular matrix; translational research; dental tissue repair

(This special issue belongs to the Section Regenerative Engineering)

Synthesis, Characterization, and Application of Biomacromolecules and Biobased Polymers

edited by

Shichao Ding

and Wenzhuo Chen

submission deadline 20 Dec 2025 | 1 articles | Viewed by 1160 | Submission Open

Keywords: biomacromolecules; biobased polymers; synthesis; characterization; engineered biomaterial; biopharmaceuticals

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Machine Learning in Precision Oncology: Innovations and Applications

edited by Sheida Nabavi and

Jun Bai

submission deadline 20 Dec 2025 | Viewed by 171 | Submission Open

Keywords: generative models in oncology; machine learning in cancer research; large language models in cancer; diffusion models; synthetic medical data; AI-driven cancer diagnosis; deep learning for oncology; personalized cancer therapy; cancer imaging and reconstruction; predictive modeling in oncology; data augmentation in medical imaging; bioinformatics and generative AI; multi-omics integration; digital pathology and AI; computational oncology; clinical decision support systems

(This special issue belongs to the Section Biosignal Processing)

Biomedical Applications of Intelligent Ultrasound Imaging

edited by

Guangquan Zhou

submission deadline 25 Dec 2025 | Viewed by 111 | Submission Open

Keywords: artificial intelligence (AI) in ultrasound; deep learning for medical imaging; explainable AI in medical imaging; intelligent ultrasound imaging; AI-powered diagnostics; ultrasound image segmentation; multimodal data fusion (CT/MRI)

(This special issue belongs to the Section Biosignal Processing)

Fetal-Maternal Monitoring during Pregnancy and Labor: Trends and Opportunities

edited by

and

Martin Gerbert Frasch

submission deadline 31 Dec 2025 | 9 articles | Viewed by 40196 | Submission Open

Keywords: fetal monitoring; perinatal medicine; antenatal care; pregnancy; signal processing; artificial intelligence; simulators

(This special issue belongs to the Section Biosignal Processing)

Electromagnetic Regenerative Bioengineering: Updates and Future Directions

edited by

Alfredo Franco-Obregón

submission deadline 31 Dec 2025 | 8 articles | Viewed by 29604 | Submission Open

Keywords: mitochondria; oxidative stress; electromagnetism; ROS (reactive oxygen species); photons; calcium channels; cancer; regenerative medicine

(This special issue belongs to the Section Regenerative Engineering)

Advanced Biomaterials, Coatings, and Techniques: Applications in Medicine

edited by Yong Hou

submission deadline 31 Dec 2025 | 8 articles | Viewed by 17894 | Submission Open

Keywords: biomaterials; coatings; advanced techniques; medical devices; implants; tissue engineering; biocompatibility; 3D printing; nanotechnology; surface modification

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Medical Artificial Intelligence and Data Analysis

edited by Ujjwal Baid and Bhakti Baheti

submission deadline 31 Dec 2025 | 7 articles | Viewed by 16088 | Submission Open

Keywords: artificial intelligence; deep learning; medical image classification; medical image segmentation; medical image registration; lesion identification and localization

(This special issue belongs to the Section Biosignal Processing)

Biomechanics of Physical Exercise

edited by

Andrea Biscarini

submission deadline 31 Dec 2025 | 6 articles | Viewed by 10625 | Submission Open

Keywords: biomechanics; kinematics; kinetics; muscle activation; joint loads; proprioception; postural control and balance; neuromotor control; human movement; physical exercise; athletic training; athletic performance; sport; injury prevention; rehabilitation; exercise equipment; equipment design; ergonomics; motion analysis; force plates; electromyography; EMG; musculoskeletal modelling; simulation; sensors; imaging; magnetic resonance; MRI; artificial intelligence; robotics; new technologies

(This special issue belongs to the Section Biomechanics and Sports Medicine)

Machine Learning and Artificial Intelligence for Biomedical Applications, 3rd Edition

edited by

Crescenzio Gallo

submission deadline 31 Dec 2025 | 7 articles | Viewed by 10499 | Submission Open

Keywords: artificial intelligence models; biomedicine; machine learning methods; artificial neural networks; precision medicine; personalized health care

(This special issue belongs to the Section Biosignal Processing)

Advancements in Biomechanical Gait Analysis: Implications for Footwear Biomechanics and Sports Injury Prevention

edited by

Yang Song

Dong Sun

and

Xuanzhen Cen

submission deadline 31 Dec 2025 | 2 articles | Viewed by 9069 | Submission Open

Keywords: human locomotion; motion capture technology; wearable sensors; biomechanical modeling; injury risk assessment; personalized footwear design; machine learning in biomechanics; sports science integration

(This special issue belongs to the Section Biomechanics and Sports Medicine)

Electric, Magnetic, and Electromagnetic Fields in Biology and Medicine: From Mechanisms to Biomedical Applications: 3rd Edition

edited by

Anna Sannino

and

Stefania Romeo

submission deadline 31 Dec 2025 | 7 articles | Viewed by 8719 | Submission Open

Keywords: electromagnetic bio-effects; interaction mechanisms; environmental health; cooperative effects; electromagnetic field modelling; exposure assessment; EMF risk assessment; diagnostic and therapeutic applications; experimental studies; electroporation and electrochemotherapy; EMF measurements; electromagnetic dosimetry

Biomedical Application of Big Data and Artificial Intelligence—Second Edition

edited by

Yan Pei

and

Jijiang Yang

submission deadline 31 Dec 2025 | 3 articles | Viewed by 7421 | Submission Open

Keywords: artificial intelligence; big data; image processing; data mining; soft computing; bioinformatics; bioengineering; healthcare

(This special issue belongs to the Section Biosignal Processing)

Anaerobic Digestion Advances in Biomass and Waste Treatment

edited by

Tina Kegl

and Breda Kegl

submission deadline 31 Dec 2025 | 5 articles | Viewed by 6319 | Submission Open

Keywords: waste management; biomass and waste pre-treatments; anaerobic digestion; modeling and optimization; biogas plants; biogas production; digestate treatment; microbial fuel cells; electricity production

(This special issue belongs to the Section Biochemical Engineering)

Recent Advances in the Application of Mathematical and Computational Models in Biomedical Science and Engineering (2nd Edition)

edited by

Sundeep Singh

Roderick Melnik

and Manpreet Singh

submission deadline 31 Dec 2025 | 2 articles | Viewed by 5725 | Submission Open

Keywords: modeling and simulation; biomedical engineering; medical physics; multiphysics and multiscale models; biomedical therapy; neurotechnology; regenerative medicine; drug delivery; data-driven models; machine learning; patient-specific models

(This special issue belongs to the Section Biosignal Processing)

Intelligent Systems for Human Action Recognition

edited by

Mondher Bouazizi

, Yue Yin and Tomoaki Ohtsuki

submission deadline 31 Dec 2025 | 3 articles | Viewed by 5695 | Submission Open

Keywords: wearable sensors; IoT devices; action recognition; computer vision; video analysis; image processing; pattern recognition; human– robot interaction; healthcare; biomedical sensing; biosignal processing; signal processing; activity detection; deep learning; AI

(This special issue belongs to the Section Biosignal Processing)

Label-Free Cancer Detection

edited by

Raphaël Canadas

submission deadline 31 Dec 2025 | 5 articles | Viewed by 5694 | Submission Open

Keywords: label-free; microfluidics; biomarkers; cancer; non-invasive; biosensors; nanotechnology

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

AI and Data Science in Bioengineering: Innovations and Applications

edited by

Muneer Ahmad

submission deadline 31 Dec 2025 | 2 articles | Viewed by 4749 | Submission Open

Keywords: AI; data science; bioengineering; biomedical engineering; predictive modeling; machine learning; smart biomaterials; tissue engineering

(This special issue belongs to the Section Biosignal Processing)

Tissue Engineering and Regenerative Medicine Strategies for Biomedical Engineering

edited by Hun-Jin Jeong and

Solaiman Tarafder

submission deadline 31 Dec 2025 | 2 articles | Viewed by 4295 | Submission Open

Keywords: tissue engineering; regenerative medicine; bioprinting; microfluidics; tissues on chip

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Engineering Neural Motor Control: From Mechanisms to Neural Interfaces

edited by Eizo Miyashita and Yuki Ueyama

submission deadline 31 Dec 2025 | 1 articles | Viewed by 3755 | Submission Open

Keywords: systems neuroscience; computational neuroscience; motor control; motor learning; motor dysfunction; rehabilitation; neuromodulation; human argumentation

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Emerging Nanomaterials and Nanotechnologies for Biomedical and Related Applications

edited by

Dipak Maity

and

Mangilal Agarwal

submission deadline 31 Dec 2025 | 3 articles | Viewed by 3732 | Submission Open

Keywords: nanomaterials; nanotechnologies; biomedical applications; drug delivery systems; biosensors; tissue engineering; cancer therapeutics; diagnostics; biomedical imaging; photothermal therapy; chemodynamic therapy; cardiovascular diseases; infection control; neurological diseases; orthopedics

(This special issue belongs to the Section Nanobiotechnology and Biofabrication)

New Sights of Deep Learning and Digital Model in Biomedicine

edited by

John A. St. Cyr

submission deadline 31 Dec 2025 | 2 articles | Viewed by 3649 | Submission Open

Keywords: deep learning; digital model; biomedicine

(This special issue belongs to the Section Biosignal Processing)

3D Cell Culture Systems: Current Technologies and Applications

edited by

Peggy Stock

submission deadline 31 Dec 2025 | 3 articles | Viewed by 3563 | Submission Open

Keywords: 3D cell culture; tissue engineering; biomaterials; drug discovery; cancer research; regenerative medicine; scaffold technology; high-throughput screening; organoids; in vitro models

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Integrative Bioengineering in Orthopedic Surgery: From Regenerative Constructs to Precision Arthroplasty

edited by Man Soo Kim

submission deadline 31 Dec 2025 | 1 articles | Viewed by 3557 | Submission Open

Keywords: orthopedic bioengineering; tissue-engineered constructs; stem cell therapy; robotic surgery; AI-guided arthroplasty; smart implants; biomechanical modeling; scaffold-implant hybrid systems; regenerative surgery; precision orthopedics

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Smart Applications and Technology for Cardiovascular Disease Management

edited by Alexander Samol and Sven Kaese

submission deadline 31 Dec 2025 | 2 articles | Viewed by 3421 | Submission Open

Keywords: cardiovascular disease; smart applications; technology; wearable devices; artificial intelligence; telemedicine; virtual reality

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Next-Generation Diagnostic and Therapy Systems for Neurodegenerative Diseases

edited by

Raji Sundararajan

and

Miad Faezipour

submission deadline 31 Dec 2025 | 3 articles | Viewed by 3409 | Submission Open

Keywords: Alzheimer's disease; Parkinson's disease; machine learning; deep learning; neurostimulation; neuromodulation; artificial intelligence models

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Nerve Regeneration

edited by Luca Cicero,

Claudia Giampietri

and

Munmun Chattopadhyay

submission deadline 31 Dec 2025 | 2 articles | Viewed by 2696 | Submission Open

Keywords: nerve regeneration; neuroengineering; biomaterials; stem cells; neuroprosthetics; biomedical devices

(This special issue belongs to the Section Regenerative Engineering)

Dentistry Regenerative Medicine and Oral Bioengineering

edited by

Aylin Baysan

and Viresh Chopra

submission deadline 31 Dec 2025 | 1 articles | Viewed by 2497 | Submission Open

Keywords: dentistry; regenerative medicine; oral bioengineering; tissue engineering; biomaterials

(This special issue belongs to the Section Regenerative Engineering)

Materials and Methods for Genetic and Cell-Based Therapy for Ocular Tissue

edited by Jesse Sengillo

submission deadline 31 Dec 2025 | 1 articles | Viewed by 1953 | Submission Open

Keywords: retinal injury; retinal repair; biomaterials; surgical techniques; drug delivery systems; imaging modalities; stem cell therapy; gene therapy; regenerative medicine

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Advances in Physical Therapy and Rehabilitation, 2nd Edition

edited by

Alvaro N. Gurovich

and

Shashwati Geed

submission deadline 31 Dec 2025 | 2 articles | Viewed by 1718 | Submission Open

Keywords: biomedical engineering; rehabilitation engineering; biomechanics; motor control; applied physiology; 3D printing; additive manufacture; imaging; ultrasound

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Soft and Flexible Sensors for Biomedical Applications

edited by Martina Maselli and Parisa Pour Shahid Saeed Abadi

submission deadline 31 Dec 2025 | 1 articles | Viewed by 1545 | Submission Open

Keywords: stretchable electronics; flexible sensors; biomedical applications; wearable devices; conformable materials; health monitoring

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Biological Wastewater Treatment and Resource Recovery, 2nd Edition

edited by

Omprakash Sarkar

Naresh Kumar Amradi

and J. Shanthi Sravan

submission deadline 31 Dec 2025 | 1 articles | Viewed by 1483 | Submission Open

Keywords: wastewater treatment; nutrient recovery; bioenergy generation; biobased products; anaerobic digestion; volatile fatty acids; bioammonium; bioelectricity

(This special issue belongs to the Section Biochemical Engineering)

Advanced Polymeric Materials for Bone, Cartilage, and Skeletal Muscle Regeneration

edited by

Jian Li

submission deadline 31 Dec 2025 | 1 articles | Viewed by 514 | Submission Open

Keywords: polymeric materials; bone regeneration; cartilage repair; skeletal muscle regeneration; 3D bioprinting; drug delivery systems; biodegradable polymers; smart materials

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Recent Advances in Biotechnology and Applied Microbiology

edited by

Ranjith Kumar Manoharan

and

Sathiyaraj Srinivasan

submission deadline 31 Dec 2025 | Viewed by 395 | Submission Open

Keywords: probiotics; postbiotics; biofilms; antimicrobial resistance; multidrug-resistant bacteria; genomics; microbiome; functional foods

(This special issue belongs to the Section Biochemical Engineering)

Emerging Roles of Large Language and Foundation Models in Pathology

edited by Zeynettin Akkus

submission deadline 31 Dec 2025 | Viewed by 297 | Submission Open

Keywords: large language models (LLMs); foundation models; digital pathology; histopathology image analysis; self-supervised learning; multi-modal AI; clinical decision support; retrieval-augmented generation (RAG); explainable AI (XAI); translational pathology

(This special issue belongs to the Section Biosignal Processing)

Bio-Scaffold Engineering for Soft Tissue Regenerative Medicine

edited by Zhonggang Feng

submission deadline 31 Dec 2025 | Viewed by 275 | Submission Open

Keywords: bio-scaffold engineering; decellularization; 3D bio-printing; hydrogel; polymer; natural materials; electrospinning; mechanical environment; cellular homeostasis; simulation

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Advances and Applications of Neuroimaging

edited by Richard James Addante and Sujoy Ghosh-Hajra

submission deadline 31 Dec 2025 | Viewed by 248 | Submission Open

Keywords: neuroimaging; fMRI; EEG; ERPs; TMS; tDCS; tACS; rTMS; MRI; PET; iEEG; sEEG

(This special issue belongs to the Section Biosignal Processing)

Cardiac Tissue Engineering: From Tissue Regeneration to In Vitro Tissue Models

edited by

Elisabetta Rosellini

and Laurie Boyer

submission deadline 31 Dec 2025 | Viewed by 244 | Submission Open

Keywords: cardiac tissue engineering; heart-on-a-chip; stem cell therapy

(This special issue belongs to the Section Regenerative Engineering)

Bioactive Ceramics in Regenerative Medicine: From Bone Grafts to Dental Implants

edited by Wenfan Chen

submission deadline 31 Dec 2025 | Viewed by 239 | Submission Open

Keywords: bioceramics; dental implants; bone grafts; regenerative medicine; bone regeneration; biomaterials; three-dimensional printing

(This special issue belongs to the Section Regenerative Engineering)

Voice Analysis Techniques for Medical Diagnosis

edited by

Shinichi Tokuno

and

Antonio Lanata

submission deadline 31 Dec 2025 | Viewed by 221 | Submission Open

Keywords: voice biomarker; diagnosis; monitoring; severity assessment

(This special issue belongs to the Section Biosignal Processing)

Recent Advances in Brain Stimulation Technology

edited by

Paolo Belardinelli

and

Giulia Liberati

submission deadline 31 Dec 2025 | Viewed by 220 | Submission Open

Keywords: brain stimulation; state-dependent brain stimulation; brain disorders; deep brain stimulation; transcranial magnetic stimulation; transcranial electrical stimulation; temporal interference stimulation

(This special issue belongs to the Section Biosignal Processing)

Artificial Intelligence in Medical Image Processing and Segmentation, Third Edition

edited by

Bernard Chiu

submission deadline 31 Dec 2025 | Viewed by 216 | Submission Open

Keywords: medical image processing; image segmentation; computer-aided diagnosis; image-guided surgery; artificial intelligence

(This special issue belongs to the Section Biosignal Processing)

Machine Learning-Driven Innovations in Predictive Healthcare

edited by

Julfikar Haider

, Sang Won Park and

Mominul Ahsan

submission deadline 31 Dec 2025 | Viewed by 205 | Submission Open

Keywords: machine learning; clinical data analysis; medical decision support; disease prediction; personalized medicine

(This special issue belongs to the Section Biosignal Processing)

Advancements in Imaging and Sensing of Single Multi-Functional Nanoparticles, Viruses and Organelles

edited by Michelle A. Digman, Qimei Zhang, Jian Yang and

Georgios Alexandrakis

submission deadline 31 Dec 2025 | Viewed by 162 | Submission Open

Keywords: super-resolution microscopy; hyperspectral imaging; nanopore sensing; plasmonics; lipid nanoparticles; liposomes; quantum dots; virus; cell organelles

(This special issue belongs to the Section Nanobiotechnology and Biofabrication)

Recent Advances in Biomedical Imaging, Third Edition

edited by

Cuneyt M. Alper

submission deadline 31 Dec 2025 | Viewed by 144 | Submission Open

Keywords: imaging innovations; advances in imaging CT; scans MRI; ultrasound nuclear medicine; PET fluoroscopy; interventional radiology; combined imaging modalities; automated segmentation; machine learning

(This special issue belongs to the Section Biosignal Processing)

Bioengineering Technologies for Spine Research

edited by Hyoungmin Kim

submission deadline 31 Dec 2025 | Viewed by 133 | Submission Open

Keywords: spine biomechanics; spinal implants and devices; computational modeling; tissue engineering; biomedical imaging; artificial intelligence; motion analysis; surgical robotics; regenerative medicine; predictive modeling; personalized spine care; translational bioengineering; smart materials; image-guided interventions

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Advancements in Imaging Techniques for Assessing Bone Health and Regeneration

edited by William Querido

submission deadline 31 Dec 2025 | Viewed by 123 | Submission Open

Keywords: bone imaging techniques; multimodal and spectral imaging; high-resolution microscopy and tomography; advanced bone histopathology; bone composition and microarchitecture; machine learning in biomedical imaging

(This special issue belongs to the Section Biosignal Processing)

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