Microtissues in Cell Culture, 3D Printing and Tissue Engineering
A special issue of Bioengineering (ISSN 2306-5354).
Deadline for manuscript submissions: closed (15 July 2024) | Viewed by 429
Special Issue Editors
Interests: induced pluripotent stem cells; cardiac tissue engineering; cardiac cell therapy; microtissues and organoids
Special Issue Information
Dear Colleagues,
Microtissues (MTs) have gained importance in the field of bioengineering in recent years. MTs can be composed of a single cell type or different cell types and thus exhibit very different degrees of complexity. Their size ranges from aggregates of a few cells to complex 3D assemblies of several hundred micrometers in diameter. In vitro, MTs are generated with or without a synthetic matrix and serve many different tasks. MTs can be used in cell culture to expand sensitive cells in 3D culture. Furthermore, MTs and especially organoids as very complex forms of MTs are used for the construction of in vitro test systems and the development of culture models to avoid animal experiments. MTs are also of particular interest as building blocks for 3D printing of tissues in vitro and transplantation in vivo in regenerative medicine applications. The current Special Issue brings MT-based bioengineering technologies into focus. Topics for this issue include manuscripts dealing with i.) scaffold-based and scaffold-free technologies to generate MTs in vitro, ii.) MTs as a technological platform to culture sensitive cells, iii.) technologies to print MTs via 3D tissue printing approaches, iv.) basic research approaches to understand cell–cell and cell–matrix communication as well as intracellular signaling in MTs, and v.) novel tools to analyze MTs including non-invasive readout suitable for high-throughput and longitudinal measurements.
Dr. Kurt Pfannkuche
Dr. Nadine Nottrodt
Guest Editors
Manuscript Submission Information
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Keywords
- microtissues
- tissue engineering
- 3D printing
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