Electric, Magnetic, and Electromagnetic Fields in Biology and Medicine: From Mechanisms to Biomedical Applications: 4th Edition

A Special Issue of Bioengineering (ISSN 2306-5354) belonging to the section "Biomedical Engineering and Biomaterials".

Deadline for manuscript submissions: 25 October 2026 | Viewed by 850

Editors


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Guest Editor
Institute for Electromagnetic Sensing of the Environment (IREA), National Research Council, 80124 Napoli, Italy
Interests: electromagnetic bio-effects; bioelectromagnetics; cellular and molecular biology; electroporation; fluorescence and confocal microscopy; mammalian cells exposed to electromagnetic fields in in vitro studies; systematic reviews; electromagnetic fields exposure assessment; biocompatibility of nanomaterials
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
Institute for Electromagnetic Sensing of the Environment (IREA), National Research Council, 80124 Napoli, Italy
Interests: electromagnetic fields; bioelectromagnetics; electromagnetic dosimetry; electroporation; biomedical applications of electromagnetic fields; electromagnetic fields exposure assessment; systematic reviews
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,  

Following the success of the 3rd Special Issue of “Electric, Magnetic, and Electromagnetic Fields in Biology and Medicine: From Mechanisms to Biomedical Applications: 3rd Edition” (https://www.mdpi.com/journal/bioengineering/special_issues/22Z19R6U62), we decided to launch a 4th edition of the Special Issue. Electric, magnetic, and electromagnetic fields (EMFs) are widely used in everyday life and in specific occupational environments. EMF-based technologies employ different parts of the spectrum, from static fields to low- and high-frequency electromagnetic fields encompassing millimeter waves and THz.  

Exposure to these fields raises concerns about the possible effects on human health, especially due to the diffusion of 5G networks, which are expected to have a major impact on exposure scenarios. On the other hand, biomedical applications of non-ionizing radiation are successfully employed for diagnosis and therapy (e.g., electroporation-based treatments, microwave hyperthermia, etc.). There is great interest in evaluating the associated interaction mechanisms, which are also relevant to foster the development of new biomedical applications or the optimization of the existing ones.  

This Special Issue is open to scientific studies addressing in vitro, in vivo, and epidemiological investigations on electric, magnetic, and electromagnetic exposure aimed at evaluating possible health effects, the beneficial potential of such fields for diagnosis and therapy, and studies focusing on interaction mechanisms. This includes work in any frequency range, which covers exposure assessment, dosimetry, risk assessment, communication, and management. Researchers and scholars from industry, academia, and government are invited to submit full research and/or review, systematic review, and meta-analysis papers to this Special Issue. 

Dr. Anna Sannino
Dr. Stefania Romeo
Guest Editors

Manuscript Submission Information

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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-anonymized peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Bioengineering is an international peer-reviewed open access monthly journal published by MDPI.

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Keywords

  • electromagnetic bio-effects
  • interaction mechanisms
  • environmental health
  • cooperative effects
  • electromagnetic field modelling
  • exposure assessment
  • EMF risk assessment
  • diagnostic and therapeutic applications
  • experimental in vitro and in vivo studies
  • electroporation and electrochemotherapy
  • EMF measurements
  • electromagnetic dosimetry

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Published Papers (1 paper)

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Research

14 pages, 18925 KB  
Article
Platelet-Rich Plasma (PRP) Assessment in Degenerative Discovertebral Complexes (DVC) Using Quantitative MRI at 4.7T: A Preliminary Animal In Vivo Study
by Benjamin Dallaudière, Emeline J. Ribot, Laurence Dallet, Aurélien J. Trotier, Olivier Thibaudeau, Sylvain Miraux and Olivier Hauger
Bioengineering 2026, 13(8), 909; https://doi.org/10.3390/bioengineering13080909 - 11 Aug 2026
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Abstract
This exploratory in vivo study investigated the therapeutic potential of intradiscal platelet-rich plasma (PRP) in a rat model of degenerative disc disease (DDD) using quantitative 4.7-T MRI and histologic correlation. Eight female Sprague-Dawley rats underwent induction of disc–vertebral complex degeneration through combined mechanical [...] Read more.
This exploratory in vivo study investigated the therapeutic potential of intradiscal platelet-rich plasma (PRP) in a rat model of degenerative disc disease (DDD) using quantitative 4.7-T MRI and histologic correlation. Eight female Sprague-Dawley rats underwent induction of disc–vertebral complex degeneration through combined mechanical injury and type I collagenase injection. Immediately thereafter, a single intradiscal injection of leukocyte-poor PRP was administered. Longitudinal MRI evaluation included 3D ultrashort echo time (UTE) imaging, T1 mapping, and T2 mapping at baseline and during follow-up. In untreated discs, degeneration was associated with progressive decreases in nucleus pulposus T1 and T2 values and increased annulus fibrosus T2 values, reflecting dehydration and structural disorganization. In contrast, PRP-treated discs showed relative preservation of nucleus pulposus T1 and T2 relaxation times, while annulus fibrosus T2 values remained more stable, suggesting attenuation of degenerative changes. UTE-derived signal changes were less discriminatory between treated and untreated groups. Histologic analysis confirmed severe nucleus pulposus and annulus fibrosus disorganization in untreated discs, whereas PRP-treated discs demonstrated milder alterations with preserved vertebral endplate architecture. Overall, these preliminary findings suggest that the longitudinal effect of a treatment through intradiscal PRP is feasible and this injection may modulate early degenerative changes in the current animal model. However, the results should be interpreted with caution because of the exploratory design, the aggressive animal degeneration model, the absence of a sham-injection comparator group, and the small number of animals studied. Full article
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