Bacterial-Host-Biomaterial Interactions for Novel Antimicrobial Strategies

Dear Colleagues,

Biomaterial-associated infection (BAI) is one of the most common and worst complications of medical implants and devices. The number of BAIs are increasing and represent more than half of all nosocomial infections. BAI is believed to be caused by microorganisms that grow in biofilms, which are difficult to diagnose and treat. In addition, the global rise in antimicrobial resistance requires urgent innovative alternatives to antibiotics. Understanding the pathogenesis of BAI and evaluating new antimicrobial strategies are important approaches for infection control.

This Special Issue will include studies with focus on the relationship between the following: biomaterial properties, microorganisms and host cells (immune and regenerative cells); aspects of the pathogenesis, diagnosis, therapy and strategies for the infection control of biomaterial-associated infections; mechanisms of biofilm development on biomaterials; biofilm-related antimicrobial resistance and antibiofilm strategies; as well as translational studies and experimental models of biomaterial-associated infection for the assessment of novel antimicrobial strategies.

Assoc. Prof. Dr. Margarita Trobos
Prof. Dr. Peter Thomsen
Guest Editors

Manuscript Submission Information

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• bacteria
• host defense
• biomaterial-associated infection
• biofilm
• antimicrobial