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Antibiotics publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Antibiotic Stewardship Implementation Strategies

edited by

Massimo Sartelli

submission deadline 15 Mar 2026 | 5 articles | Viewed by 6283 | Submission Open

Keywords: antibiotic stewardship; implementation; hospital settings

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Antibiotics for Primary Care Practice

edited by Reza Nassiri

submission deadline 15 Mar 2026 | Viewed by 558 | Submission Open

Keywords: primary care practice; nursing home practice; remote practice; antibiotic prescription habits; antibiotic resistance in clinical practice; public health consequences of antibiotic resistance; antibiotics stewardship practices; elements of safe practice

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Surveillance of Carbapenem-Resistant Microbes and Strategies to Combat Them

edited by Daniela Cejas and Marcela Radice

submission deadline 15 Mar 2026 | Viewed by 238 | Submission Open

Keywords: antibiotic resistance; epidemiology; carbapenemases; carbapenem resistance; enterobacterales; acinetobacter baumannii; resistance plasmids; surveillance; genomics; high-risk clones

(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)

Challenges and Emerging Strategies to Tackle the Global Burden of Antimicrobial Resistance

edited by

Tomislav Meštrović

submission deadline 20 Mar 2026 | 4 articles | Viewed by 15792 | Submission Open

Keywords: antimicrobial resistance (AMR); global burden of AMR; AMR in the context of public and global health; diagnostic and treatment of AMR; new approaches to AMR surveillance; antibiotic stewardship; local and global policy initiatives on AMR; prevention of AMR

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Antibiotic Resistance in Hospital-Acquired Infections

edited by Andreea-Loredana Golli,

Ovidiu Zlatian

and

Alice Elena Ghenea

submission deadline 20 Mar 2026 | 6 articles | Viewed by 7476 | Submission Open

Keywords: healthcare-associated infections; multi-drug resistance; epidemiology; antimicrobial therapy; patient outcomes; infection prevention and control strategies

(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)

Hospital-Acquired Infections, Multidrug Resistant (MDR) Bacteria, AI, and Alternative Approaches to Antibiotic Therapy

edited by

Susu Zughaier

and

Nayeem Ahmad

submission deadline 20 Mar 2026 | Viewed by 82 | Submission Open

Keywords: antimicrobial resistance; hospital-acquired infections; multidrug resistant; artificial intelligence; nosocomial infection; molecular mechanism of resistant bacteria

(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)

Linking Genomic Mutations to Antimicrobial Resistance and Virulence

edited by

Eduardo Alvarez Duarte

submission deadline 30 Mar 2026 | Viewed by 85 | Submission Open

Keywords: antifungal resistance; antifungal drugs; antibiotics; resistance; antimicrobial resistance; genetic mutations; SNP

(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)

Optimizing Antibiotic Use and Consumption: Integrating Surveillance, Policy and Practice

edited by

Paola Lichtenberger

submission deadline 30 Mar 2026 | Viewed by 53 | Submission Open

Keywords: infectious disease; antimicrobial stewardship; antibiotic use; antimicrobial consumption; point prevalence survey

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Antimicrobials Use: Clinical Safety to Environmental Risk—Learning from One Health Approach

edited by

Anabela Almeida

Leonor M. Meisel

and

Ana Fortuna

submission deadline 31 Mar 2026 | 8 articles | Viewed by 37614 | Submission Open

Keywords: antimicrobials; antifungals; antiviral; environment; antimicrobial resistance; pharmacokinetics; risk-assessment; prioritisation; One-Health

Antibiotics as Major Disruptors of Gut Microbiota

edited by

Gábor Ternák

submission deadline 31 Mar 2026 | 6 articles | Viewed by 30639 | Submission Open

Keywords: microbiome; gut flora; development of gut flora; dysbiosis; antibiotics; antibiotic classes; antibiotic consumption; gut– brain axis; short-chain fatty acids; metabolom; mediator molecules; composition of gut flora

Membranes to Fight Drug-Resistant Microbes

edited by

Nermina Malanovic

submission deadline 31 Mar 2026 | 6 articles | Viewed by 21135 | Submission Open

Keywords: antimicrobial peptides; membrane-active compounds; mode of action; lipidoids; vaccines

(This special issue belongs to the Section Antimicrobial Peptides)

Antibiotic Resistance: From the Bench to Patients, 2nd Edition

edited by

Fernando Albericio

and

Márió Gajdács

submission deadline 31 Mar 2026 | 4 articles | Viewed by 10526 | Submission Open

Keywords: antimicrobial resistance; infectious disease epidemiology; multidrug resistance; clinical bacteriology; antimicrobial stewardship; self-medication; knowledge– attitude– practice (KAP); regulatory perspectives; drug utilization; policy analysis; primary care; pharmacy; novel antimicrobial drugs; laboratory testing

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Strategies to Combat Antibiotic Resistance and Microbial Biofilms

edited by

Isabella Macário Ferro Cavalcanti

submission deadline 31 Mar 2026 | 4 articles | Viewed by 9175 | Submission Open

Keywords: antibiotic resistance; biofilms; nanotechnology; medicinal plants; synthetic

(This special issue belongs to the Section Novel Antimicrobial Agents)

Companion Animals: Antimicrobial Resistance in Bacterial and Fungal Pathogens Associated with Skin and Ear Infections

edited by

Dominik Łagowski

and

Ewelina Czyzewska-Dors

submission deadline 31 Mar 2026 | 4 articles | Viewed by 8339 | Submission Open

Keywords: dermatophytes; Candida; companion animals; drug susceptibility; Malassezia; mechanisms of resistance; molecular detection; Pseudomonas; Staphylococcus; One Health; MDR; veterinary

(This special issue belongs to the Section Antibiotics in Animal Health)

Antibiotics: Fighting Disease and Promoting Health by Embracing the Two Sides of the Same Coin

edited by

Chrysoula Voidarou

Elisavet Stavropoulou

and

Eugenia Bezirtzoglou

submission deadline 31 Mar 2026 | 2 articles | Viewed by 7968 | Submission Open

Keywords: antibiotics; probiotics; antibacterial activity; functional food; natural compounds; natural antimicrobials; microbiome; antimicrobial resistance; resistome

(This special issue belongs to the Section The Global Need for Effective Antibiotics)

Genomic Insights and Implications of Emerging Antimicrobial Resistance

edited by

Daniela Bencardino

and

Christian Berens

submission deadline 31 Mar 2026 | 4 articles | Viewed by 5655 | Submission Open

Keywords: antibiotic-resistance; molecular typing; genomic technologies; high-threat pathogens; epidemiological surveillance; emerging and re-emerging infectious diseases; one health approach

(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)

Advancing and Standardising Antimicrobial Susceptibility and Resistance Detection Methodology

edited by

Owen B. Spiller

submission deadline 31 Mar 2026 | 5 articles | Viewed by 4875 | Submission Open

Keywords: antimicrobial susceptibility testing; resistance screening; rapid diagnostics; clinical; veterinary; environmental; validation

(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)

Antibiotics Resistance in Animals and the Environment, 2nd Edition

edited by

Anil Poudel

submission deadline 31 Mar 2026 | 2 articles | Viewed by 4430 | Submission Open

Keywords: antimicrobial resistance; environment; epidemiology; genomics; multi-drug resistance; sympatric; wildlife

(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)

Antimicrobial and Antioxidant Efficacy of Essential Oils

edited by

Mijat Božović

submission deadline 31 Mar 2026 | 1 articles | Viewed by 4111 | Submission Open

Keywords: essential oils; chemical analysis; extraction methods; antimicrobial activity; antioxidant potential

(This special issue belongs to the Section Plant-Derived Antibiotics)

Periodontal Bacteria and Periodontitis: Infections and Therapy

edited by Anna Skurska

submission deadline 31 Mar 2026 | 3 articles | Viewed by 4038 | Submission Open

Keywords: periodontitis; infection; antibiotics; antibacterial activities

(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)

Advances in Infective Endocarditis Research: From Bench to Bedside

edited by Joya-Rita Hindy

submission deadline 31 Mar 2026 | 3 articles | Viewed by 3290 | Submission Open

Keywords: infective endocarditis; prosthetic valve endocarditis; cardiac implantable electronic devices; recurrent infective endocarditis; valvular heart disease; cardiac surgery; molecular diagnostics; innovative drug delivery; antimicrobial resistance; suppressive therapy

(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)

Antimicrobial Activities of Bioactive Components from Honeybee Products

edited by

Otilia Bobis

Adriana Cristina Urcan

and

Claudia Pașca

submission deadline 31 Mar 2026 | 1 articles | Viewed by 3250 | Submission Open

Keywords: bee products; antibiotics; antimicrobial activity; bioactive compounds; honey; propolis; bee pollen/beebread; royal jelly; bee venom; microbial resistance

(This special issue belongs to the Section Novel Antimicrobial Agents)

Epidemiology and Genomics of Antimicrobial Resistance of Difficult-to-Treat Pathogens

edited by Simone Ambretti

submission deadline 31 Mar 2026 | 3 articles | Viewed by 2873 | Submission Open

Keywords: antimicrobial resistance; difficult-to-treat pathogens; epidemiology; genomics; MRSA; VRE; ESBL; CRE; CRAB; MDR pseudomonas aeruginosa

(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)

Nanotechnology-Based Antimicrobials and Drug Delivery Systems

edited by

Mihai Valentin Predoi

Simona Liliana Iconaru

and

Carmen Steluta Ciobanu

submission deadline 31 Mar 2026 | 3 articles | Viewed by 2725 | Submission Open

Keywords: antimicrobial agents; nanocarriers; antimicrobial coatings; polymers nanocomposite; drug delivery systems

(This special issue belongs to the Section Novel Antimicrobial Agents)

Antibiotic Resistance and Virulence in Bacterial Isolates: A Genomic Perspective from Human and Animal Sources

edited by

Sónia Ramos

and

Alexandra Nunes

submission deadline 31 Mar 2026 | 2 articles | Viewed by 2702 | Submission Open

Keywords: MDRB; antimicrobial resistance; one health; mobile genetic elements; AMR; antimicrobial resistance gene

(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)

Discovery of Novel Antimicrobial Peptides Using Machine Learning and Molecular Dynamic Simulations

edited by

Lei Zhao

Liang Zhao

and

Fei Pan

submission deadline 31 Mar 2026 | 1 articles | Viewed by 2141 | Submission Open

Keywords: antimicrobial peptide; computational design; machine learning; deep learning; molecular dynamic simulations; de novo generation

(This special issue belongs to the Section Antimicrobial Peptides)

Genetic Characterization of Antimicrobial Resistance under the One Health Approach

edited by

Sandra M. Quinteira

and

Olga Maria Lage

submission deadline 31 Mar 2026 | 1 articles | Viewed by 1809 | Submission Open

Keywords: antimicrobial resistance; multidrug-resistant bacteria; resistance genes; mobile genetic elements; molecular mechanisms of resistance; One Health; epidemiology of AMR; AMR surveillance

(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)

Antibiotics in the Environment: Sources, Fate, and Mitigation Strategies

edited by Khaled Benis

submission deadline 31 Mar 2026 | 1 articles | Viewed by 1781 | Submission Open

Keywords: antibiotic contamination; environmental fate; antibiotic resistance; mitigation strategies; pollution management

A Themed Issue in Honor of Prof. Dr. Rob Capon—Outstanding Contributions in the Field of Anti-Infectives

edited by Mark Butler

submission deadline 31 Mar 2026 | 1 articles | Viewed by 1362 | Submission Open

Keywords: natural product; microorganism; bacteria; fungi; marine antibiotic; antibacterial; antheminthic; crop protection

(This special issue belongs to the Section Novel Antimicrobial Agents)

New Inhibitors for Overcoming Antimicrobial Resistance

edited by

Humberto Medeiros Barreto

and

Sofia Santos Costa

submission deadline 31 Mar 2026 | 2 articles | Viewed by 1333 | Submission Open

Keywords: antimicrobial resistance; resistance mechanisms; inhibitors; enzymatic inhibitors; efflux; biofilms

Antimicrobial Peptides: Mechanisms, Engineering, and Therapeutic Development

edited by

Feng-Di Lung

submission deadline 31 Mar 2026 | 2 articles | Viewed by 994 | Submission Open

Keywords: antimicrobial peptides (AMPs); peptide engineering; mechanisms of action; antibiotic resistance; host defense peptides; immunomodulation; drug delivery systems; synergy with antibiotics; therapeutic development; computational peptide design

(This special issue belongs to the Section Antimicrobial Peptides)

Surveillance and Detection of Antimicrobial Resistance: Tools and Trends

edited by

Hung-Sheng Shang

submission deadline 31 Mar 2026 | 1 articles | Viewed by 849 | Submission Open

Keywords: antimicrobial resistance; surveillance systems; pathogen detection; rapid diagnostics; genomic surveillance; artificial intelligence; point-of-care testing; public health strategy; molecular epidemiology; big data analytics

Antibiotic Synthesis, 2nd Edition

edited by

Naresh Kumar

and

Tsz Tin Yu

submission deadline 31 Mar 2026 | 1 articles | Viewed by 651 | Submission Open

Keywords: new antimicrobial compounds; dual-action antimicrobials; new antimicrobial targets; targeted delivery of antibiotics; new scaffolds for antimicrobial discovery; discovery of new antimicrobial mechanisms

(This special issue belongs to the Section Novel Antimicrobial Agents)

Current Challenges in Antimicrobial Stewardship

edited by

Andreas A. Von Ameln-Mayerhofer

submission deadline 31 Mar 2026 | 1 articles | Viewed by 627 | Submission Open

Keywords: antimicrobial stewardship; antimicrobial resistance; antibiotics prescribing; intervention; irrational prescriptions; surveillance; therapeutic monitoring; ABS; AMS; antibiotic stewardship; best practice; interprofessional; rational prescribing; DDD/100; RDD/100

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Drivers of Virulence and Antimicrobial Resistance in Emerging and Re-Emerging Pathogens

edited by

Opeyemi U. Lawal

Ons Bouchami

and Ingrid Maria Cecilia Rubin

submission deadline 31 Mar 2026 | Viewed by 366 | Submission Open

Keywords: AMR; microbial pathogenesis; microbial ecology; pathogen dynamics; genomic epidemiology; multiomics; microbial interactions; AI/ML

(This special issue belongs to the Section Genetic and Biochemical Studies of Antibiotic Activity and Resistance)

Combating Antimicrobial Resistance Spread in Food and Drinks Using Bacteriophage Technologies

edited by

Janet Nale

submission deadline 31 Mar 2026 | 1 articles | Viewed by 350 | Submission Open

Keywords: bacteriophage; phage therapy; antimicrobial resistance; food; drink; water; agriculture; pathogenic bacteria; lytic phages; lysogens; prophages; temperate phage

(This special issue belongs to the Section Bacteriophages)

Global Partnerships in Response to Antimicrobial Resistance: From Policy to Practice

edited by

Helena Rosado

submission deadline 31 Mar 2026 | Viewed by 287 | Submission Open

Keywords: antimicrobial resistance; antimicrobial stewardship; global health partnerships; collaboration; low- and middle-income countries; health systems strengthening; actionable implementation; AMR interventions

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Interdisciplinary Applications of Micro- and Nano-Antimicrobials

edited by Cleonice Gonçalves da Rosa and Michael Ramos Nunes

submission deadline 31 Mar 2026 | Viewed by 251 | Submission Open

Keywords: micro- and nano-antimicrobials; antimicrobial coatings; nanotechnology in medicine; food safety and packaging; agricultural applications; antibiotic resistance; environmental remediation; controlled release systems; pathogen management; antimicrobial materials

(This special issue belongs to the Section Novel Antimicrobial Agents)

Antimicrobial Peptides in Agriculture and Food Safety

edited by

Da Teng

submission deadline 31 Mar 2026 | Viewed by 240 | Submission Open

Keywords: AI-based discovery and design; biotechnology; mechanisms of action; novel delivery systems; animal husbandry; aquaculture; plant conservation; food preservation

Biomaterial-Based Delivery Systems for Natural Antimicrobials to Overcome Microbial Resistance

edited by

Ioana Cristina Marinas

Irina Gheorghe-Barbu

and Ilda Czobor-Barbu

submission deadline 31 Mar 2026 | Viewed by 225 | Submission Open

Keywords: antimicrobial resistance (AMR); virulence and pathogenicity; phytocompounds; biomaterials; controlled release; nanoparticles; biopolymers; targeted delivery; biofilm prevention; sustainable therapeutics

(This special issue belongs to the Section Antimicrobial Materials and Surfaces)

Antibiotic Susceptibility Testing and Rapid Diagnostics of Antimicrobial Resistance

edited by Maria Grazia Bocci and Giulia Capecchi

submission deadline 31 Mar 2026 | Viewed by 212 | Submission Open

Keywords: antimicrobial resistance; antibiotic susceptibility testing; rapid diagnostics; molecular detection; point-of-care testing; clinical microbiology

Evaluation of Emerging Antimicrobials, 2nd Edition

edited by

Dilep Kumar Sigalapalli

submission deadline 31 Mar 2026 | Viewed by 119 | Submission Open

Keywords: antibacterials; antibiotics; antifungals; antimicrobial agents; antimicrobial resistance; antivirals; bacterial resistance; infections; multidrug resistance; pathogens

(This special issue belongs to the Section Novel Antimicrobial Agents)

Advanced Nanomaterials: Design, Synthesis, and Antibacterial Applications

edited by

Fei Pan

submission deadline 31 Mar 2026 | Viewed by 87 | Submission Open

Keywords: advanced nanomaterials; design; synthesis; antibacterial; applications

(This special issue belongs to the Section Antimicrobial Peptides)

Optimizing Empirical Antibiotic Therapy in Critical Care: Innovations in Diagnostics, Digitalization, and Stewardship

edited by

Mircea Stoian

and

Daniela C. Pasero

submission deadline 31 Mar 2026 | Viewed by 81 | Submission Open

Keywords: critical care; intensive care units; empirical antibiotic therapy; antimicrobial stewardship; rapid molecular diagnostics; digital health; artificial intelligence; antimicrobial resistance; targeted therapy; polypharmacy reduction; novel antibiotics; sepsis management

(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)

Beyond Bacteria: Exploring the Biology and Treatment of Understudied Fungal Biofilms

edited by

Whitni Redman

and

Wolf-Rainer Abraham

submission deadline 31 Mar 2026 | Viewed by 76 | Submission Open

Keywords: fungal biofilms; bacterial biofilms; interkingdom biofilms; host-pathogen interactions; biofilms and methodologies; mixed-species infections; therapeutics; fungal– bacterial interactions

(This special issue belongs to the Section Antibiofilm Strategies)

Genomic Characterization of Antimicrobial Resistance and Evolution Mechanism of Bacteria, 2nd Edition

edited by

Daniel Gyamfi Amoako

and

Linda Bester

submission deadline 31 Mar 2026 | Viewed by 42 | Submission Open

Keywords: antimicrobial resistance mechanism; mobile genetic element; horizontal gene transfer; resistome; evolution; molecular phylogenetics; genomics; bioinformatics analysis; next-generation sequencing

(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)

Antibiotic Choices for Pediatric Infections

edited by Theodouli Stergiopoulou

submission deadline 1 Apr 2026 | Viewed by 283 | Submission Open

Keywords: pediatric; neonatal infectious diseases; antimicrobial agents; antibiotic treatment

(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)

Antimicrobial Resistance of Staphylococcus spp. in Animals: A One Health Perspective

edited by Gi Yong Lee

submission deadline 5 Apr 2026 | 1 articles | Viewed by 1042 | Submission Open

Keywords: staphylococci; molecular epidemiology; antimicrobial resistance; One Health; multiomics

(This special issue belongs to the Section Antibiotics in Animal Health)

Microbial Resistance Surveillance and Management in Food Systems

edited by

Carlos Adam Conte Júnior

and

Bruno Dutra da Silva

submission deadline 20 Apr 2026 | 6 articles | Viewed by 11220 | Submission Open

Keywords: cross-contamination; microbial resistance; microbial monitoring; public health; alternative antimicrobials; foodborne illnesses; food microbiology

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

The Application of Antibiotic Therapy in Oral Surgery and Dental Implant Procedures, 2nd Edition

edited by

Angel-Orion Salgado-Peralvo

and

Eugenio Velasco-Ortega

submission deadline 20 Apr 2026 | 1 articles | Viewed by 1153 | Submission Open

Keywords: antibiotics; preventive antibiotic therapy; antibiotic prophylaxis; bacterial antibiotic resistance; antibiotic resistance; oral implantology; dental implantology; dental implants; dentistry; oral surgery

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