Special Issue "Stem Cells in Domestic Animals: Applications in Health and Production"
A special issue of Animals (ISSN 2076-2615). This special issue belongs to the section "Veterinary Clinical Studies".
Deadline for manuscript submissions: 31 December 2021.
Special Issue Editors
Interests: in vitro embryo production protocols in domestic animals and in the study of mesenchymal stem cells deriving from adult and attached fetal tissues
Special Issue Information
Dear Colleagues,
Over the past decade, stem cell research has emerged as an area of major interest for its potential applications, both in human and veterinary medicine. The effective management of companion and sport animals requires sophisticated new treatments and preventive strategies. Furthermore, also in livestock species, stem cell therapy could be used to treat several medical conditions that negatively affect meat and milk production or reproductive efficiency. In the era of antibiotic resistance, stem cells modified with therapeutic agents might be employed to combat mastitis in dairy cow, sheep, goat or buffalo, with enormous benefits also for human health. Reproductive performances could be improved by the integration of stem cells into the in vitro embryo production system, representing in another way the importance of stem cells in addressing commercial goals. Moreover, the importance of domestic animals as models for human diseases has been recognized. The quantity of tissue available for decellularization is greater than that in small animal models such as mice, and larger animal species more closely resembling some human behavior can be used for translational applications in cell therapy. Domestic animals are also models for stem cell secretome studies and clinical trials.
Prof. Eleonora Iacono
Prof. Barbara Merlo
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Animals is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- Stem cells
- Domestic animals
- Cellular therapy
- Translational medicine
- Cell culture
- Secretome
Planned Papers
The below list represents only planned manuscripts. Some of these manuscripts have not been received by the Editorial Office yet. Papers submitted to MDPI journals are subject to peer-review.
Title: The Usefulness of Mesenchymal Stem Cells Beyond the Musculoskeletal System in Horses
Authors: Alina Cequier; Carmen Sanz; Clementina Rodellar; Laura Barrachina
Affiliation: Laboratorio de Genética Bioquímica LAGENBIO - Instituto de Investigación Sanitaria de Aragón (IIS) - Instituto Agroalimentario de Aragón (IA2), Universidad de Zaragoza, C/Miguel Servet, 177. 50013 Zaragoza (Spain)
Servicio de Cirugía y Medicina Equina, Hospital Veterinario, Universidad de Zaragoza, C/Miguel Servet, 177. 50013 Zaragoza (Spain)
Abstract: In equine medicine, mesenchymal stem cells (MSCs) have been mainly studied to treat musculoskeletal injuries, owing to their ability to differentiate. However, MSC paracrine activity has widened their scope for inflammatory and immune-mediated pathologies such as ophthalmologic, respiratory or reproductive, in both equine and human medicine. The similar etiopathogenesis of some of these diseases in humans and domestic animals has advanced the concept of ‘One Medicine, One Health’. This article will review the current knowledge on the use of MSCs for equine pathologies beyond the locomotor system, highlighting the value of the horse as translational model for developing novel treatments.