Special Issue "Splenic Pathologies in Companion Animals"

A special issue of Animals (ISSN 2076-2615). This special issue belongs to the section "Companion Animals".

Deadline for manuscript submissions: 30 November 2021.

Special Issue Editors

Dr. Silvia Ferro
E-Mail Website1 Website2
Guest Editor
Department of Comparative Biomedicine and Food Science, Università degli Studi di Padova, Padua, Italy
Interests: veterinary dermatopathology; splenic pathologies of dogs and cats; oral pathologies of dogs and cats
Dr. Cinzia Centelleghe
E-Mail Website
Co-Guest Editor
Department of Comparative Biomedicine and Food Science, Università degli Studi di Padova, 35020 Legnaro, Italy
Interests: marine mammal pathology and diseases; molecular biology techniques; cell culture techniques
Special Issues and Collections in MDPI journals
Dr. Alessandro Sammarco
E-Mail Website1 Website2
Co-Guest Editor
1. Department of Comparative Biomedicine and Food Science, Università degli Studi di Padova, Padua, Italy
2. Department of Neurology and Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA
Interests: oncology; canine and feline mammary tumors; human breast cancer; metastasis; extracellular vesicles

Special Issue Information

Dear Colleagues,

The spleen is a complex multifunctional organ that can represent a clinical and surgical challenge in veterinary practice. Pathologies of the spleen are often discovered in the late phase of the disease and, when a secondary rupture of the organ occurs, they can represent a surgical emergency and a life-threatening condition. Many can be due to the lesions involved in splenic pathologies. The splenic macrophagic compartment can harbor several etiological agents involved in infectious diseases. Inflammations of the spleen are still poorly understood and probably underestimated. Because of the extended vascular component, circulatory disturbances can be responsible for organ hemorrhages. Finally, many neoplasms can arise from the splenic parenchyma, especially from the endothelial component and from the hematopoietic compartment. Early diagnosis and appropriate treatments of all these pathological entities, then, are of scientific importance in veterinary medicine. Furthermore, since the spleen is an internal organ that is difficult to reach, new alternative noninvasive methods of diagnosis are needed.

For this Special Issue, we welcome original research articles on any aspect regarding the spleen in companion animals, from infectious diseases, congenital anomalies, inflammatory diseases, and neoplastic processes to diagnosis and clinical and surgical treatments of the various entities, with a particular interest in novel techniques. Review articles are also welcome. Studies on novel splenic cell lines and on splenic cell-derived extracellular vesicles will be of particular interest.

Dr. Silvia Ferro
Dr. Cinzia Centelleghe
Dr. Alessandro Sammarco
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Animals is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • spleen
  • splenic neoplasms
  • splenic hematopoietic disorders
  • splenic hemangiosarcoma
  • splenic histiocytic sarcoma
  • splenic lymphoma
  • splenitis
  • physiopathology of splenic disorders
  • canine splenic cell line
  • extracellular vesicles
  • splenic cytology
  • companion animals

Published Papers

This special issue is now open for submission.
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