Dr. Jürgen Kratzsch is an Associate Professor and Senior Scientist responsible for endocrinological laboratory diagnostics in the Institute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics at the University Hospital of Leipzig in Germany. Professor Kratzsch completed his academic training in 1980 at the University of Leipzig, and in 1984, he obtained his PhD degree on methodological issues in hormone analytics. In 2001, he completed his second graduation in Clinical Chemistry, and in 2004, he became an Associate Professor for Clinical Chemistry at the University of Leipzig. Professor Kratzsch’s main research interests are the laboratory diagnostic of thyroid and growth hormone/IGF-related diseases, as well as the investigation of adipokines function in metabolic disorders. He is a member of various endocrinology associations. Professor Kratzsch is the deputy speaker for the Endocrinological Laboratory Diagnostics section of the German Society for Clinical Chemistry and Laboratory Diagnostics.
Prof. Dr. Dominik Seelow is a professor for Bioinformatics and Translational Genetics and research group leader at the Berlin Institute of Health (BIH) and Charité-Universitätsmedizin Berlin. His research focus is the development of user-friendly software and databases for the elucidation of monogenic disease. All applications are free to use, and most are web-based. Some examples are HomozygosityMapper, which is aimed at the discovery of disease-linked genomic regions in consanguineous families; MutationTaster for the evaluation of the disease-causing potential of DNA variants; MutationDistiller, combining gene variant and phenotype annotation for the identification of the disease mutation in WES data; RegulationSpotter, giving a user-friendly estimation of the potential impact of extra-transcriptic DNA variants; and ePOSSUM, which predicts the effect of DNA variants on transcription factor binding.
