Prof. Dr. Tjalf Ziemssen graduated in medicine from the medical schools of Bochum, Bern and London in 1998. Between 1998 and 2000, he finished his postgraduate neurological training in the department of neurology, University Clinic Dresden, Germany. In 1999, he completed his doctoral thesis in the laboratory of Prof. Michael Krieg (Institute of Clinical Chemistry, Laboratory Medicine and Transfusion Medicine, University of Bochum.). Between 2000 and 2003, Dr. Ziemssen was post-doctoral fellow of the Deutsche Forschungsgemeinschaft (DFG) and Max-Planck-Society (MPG) at the Max-Planck Institute of Neurobiology, Department of Neuroimmunology, within the groups of Prof. Reinhard Hohlfeld, Prof. Hartmut Wekerle and Dr. Antonio Iglesias. He is currently a consultant at the neurological university clinic in Dresden, head of the autonomic lab of the neuroimmunological laboratory of the MS center in Dresden, which is involved with over 1000 MS patients. In 2011, he received the professorship for clinical neuroscience at a new established center at Dresden University and is the director of the center of clinical neuroscience. Important research areas are digital neurology applied to the case of multiple sclerosis and multidimensional patient phenotyping by applying AI into the concept of MS digital twin to predict disease course and treatment response, which is a component of several funded projects.