Prof. Chiara Brullo received her degree in Chemistry and Pharmaceutical Technology in 1999 and her PhD in Pharmaceutical Chemistry in 2003 from the University of Genoa, Italy. From 2003 to 2016, she was a Research Fellow at the University of Genoa undertaking IT research and teaching. Since 2016, she has been an Associate Professor at the University of Genoa. In November 2019, she became a Member of the PhD board in the Sciences and Technologies of Chemistry and Materials department.
Prof. Enrico Millo is a Professor of Biochemistry and Lecturer in the School of Medical and Pharmaceutical Sciences of the University of Genoa and the degree course of Chemistry and Chemical Technologies of the University of Genoa. For more than 20 years, he has carried out research in the field of biological and pharmaceutical chemistry with a particular interest in the design and synthesis of biomolecules with potential pharmacological activities in various diseases such as those of the central nervous system (creatine transporter deficiency) and genetic character (cystic fibrosis). His research areas include biochemical studies applied to the design and chemical synthesis of conventional peptides and peptidomimetics as pharmacological drugs in diseases involving the misregulation of gene expression and autoimmune diseases, as well as the design and synthesis of “modulators” for the pharmacological correction of the cystic fibrosis chloride transport defect and synthesis of creatine-derived compounds for the therapy of creatine transporter deficiency.
Prof. Santina Bruzzone is a full professor of Biochemistry at the Department of Experimental Medicine (DIMES)-Section of Biochemistry, University of Genova (Italy). She obtained her PhD in Biotechnology from the University of Milano (Italy) in 2000, and she was a post-doc at the Department of Pharmacology, University of Minnesota (Minneapolis, MN; Prof. H.C. Lee’s lab). She worked for 3 years as a postdoctoral researcher at the DIMES, in the Section of Biochemistry, before obtaining a permanent position as an assistant, associate, and, recently, full professor in the same department. Her scientific interests are mainly related to NAD biology, signal transduction, and metabolism (NAD biosynthesis, NAD-converting enzymes, and NAD-derived second messengers).
Prof. Elena Cichero obtained a degree in Chemistry and Pharmaceutical Technologies in 2005 and her Ph.D in 2009 in Pharmaceutical Sciences at the University of Genoa. From 2021, she has been an Associate Professor in Medicinal Chemistry at the University of Genoa. She is an expert in several computational chemistry techniques that are used in medicinal chemistry drug design processes. She has strong skills and experience in computer-assisted drug design, including molecular docking calculations, virtual screening, and 3D-QSAR analyses. Her research topics include the development of anti-viral agents, effective compounds in neurodegenerative diseases, anticancer agents, and the discovery of novel compounds for the treatment of cystic fibrosis. Her research lines are focused on computational chemistry methods for the exploration of GPCRs, such as cannabinoid receptors, serotoninergic receptors, and trace-amine associated receptors, as well as enzymes such as phosphodiesterases and sirtuins. She has authored around 90 papers and numerous poster communications.
