Angela La Grua graduated in Experimental and Applied Biology
in 2021 at the University of Pavia and has worked as a Research Fellow at the
Humanitas Research Hospital in Rozzano since December 2021 with a project
focused on the generation and characterization of induced pluripotent stem
cells (iPSCs) derived from an Amyotrophic Lateral Sclerosis disease pig model.
Currently, she is enrolled in the XVIII cycle of the UniMi PhD program in
Experimental Medicine at the Humanitas Research Hospital. Her project is
focused on the use of the chromosome transplantation approach to rescue the
molecular defects in iPSCs from patients affected by genetic diseases.
Ilaria Rao is a MEM (Molecular and
Experimental Medicine) PhD student at Humanitas University. She graduated in
Medical, Veterinary Pharmaceutical, Biotechnologies in 2020 at the University
of Parma. During her thesis internship, she worked on a project based on
induced pluripotent stem cell (iPSC) maintenance and iPSC cardiac
differentiation. Now, her main project is based on iPSCs from human Duchenne
Muscular Dystrophy and their correction by chromosome transplantation, which is
a novel approach of gene correction defined as the perfect replacement of the
endogenous defective chromosome with an exogenous normal one, restoring a
correct diploid karyotype.
Franco Lucchini is currently working as a Researcher at the Department for Sustainable Food Process, Università Cattolica del Sacro Cuore, Piacenza, Italy. In 1988, he obtained a degree in Veterinary Medicine at the University of Milan. In the same year, he started working at the Joint Research Centre – EURATOM in Ispra (VA) and was involved as a researcher in the field of transgenic animal technology. In 1990, he was a research fellow at CNR in the framework of the “Human Genome” project. In the same year, in the framework of this project, he was a visiting researcher at the ICRF, Zoology Department of Oxford University, for training on mouse ES cell culture techniques. His research interests include Lab animals, DNA cloning, PCR, transgenic, and Intestinal Epithelial Cells.
Elena Raimondi is currently working as an Associate Professor of the Department of Biology and Biotechnology Lazzaro Spallanzani at the University of Pavia, Pavia, Italy. Elena Raimondi received PhD (Genetics and Microbiology) from the University of Pavia in 1987. Elena Raimondi's interests include centromeres and satellite DNA.
Paolo Vezzoni graduated in Medicine and Surgery in 1974 from the University of Milan. He obtained his Specialty in Endocrinology in 1977 at the University of Pavia and the Specialty of Oncology in 1980 at the University of Genova. After a period spent at the National Cancer Institute in Milan, from 1987 onwards, he has been working for more than 30 years at the National Research Council (CNR) in Milan. He co-directed the Italian Human Genome Project and his group identified several genes responsible for diseases of the bone and the immune system. More recently, he acted as Director of the Milan Section of the Institute of Genetic and Biomedical Research (IRGB) and of the Medical Biotechnology Laboratory of the Humanitas Research Center in Rozzano.
Marianna Paulis graduated in Biological Sciences in 2000 at
the University of Pavia, where she also obtained a PhD in Genetic and
Biomolecular Sciences in 2004. During her PhD, she attended the
Advanced School for Integrated Formation (SAFI) established by the University
School for Advanced Studies (IUSS) of Pavia for 3 years and achieved the certificate of
advanced post-graduate education in 2004. Since 2006, she has been working at
the National Research Council (CNR) of Milan with a Post-Doctoral position and
in 2007, in her laboratory moved to the Humanitas Research Hospital. In 2015, she
received a tenured position as a Researcher at the Institute of Genetic and
Biomedical Research (IRGB) of the CNR based in Milan. She has long-lasting
research experience and expertise in the field of classical and molecular
cytogenetics of mammalian cells and years of experience in mouse and human
pluripotent stem cells (both ESCs and iPSCs). Her main interest is in the
investigation of gene therapy approaches for genome disorders due to
chromosomal abnormalities.