Author Biographies

Alejandro Manzanares Guzmán is a graduate student in the program Doctor of Science in Biotechnology Innovation (PhD) in the Medical and Pharmaceutical Biotechnology Unit, CIATEJ, A.C., located in Guadalajara, Jalisco, Mexico (2021–present).  He works in the nanotechnology design, cloning, and production of recombinant protein (batch scale) and cell culture. He specializes in human serum albumin (HSA) polymeric nanoparticle synthesis, production, and isolation of single-domain antibodies such as vNARs with diagnostic and therapeutic applications. Currently, he works with Dr. Tanya Amanda Camacho-Villegas to develop a system based on the vNAR as an immuno-carrier for NPs for theranostic applications for glioblastoma as a model.  He has received a BSc in biology from the Science Faculty, Universidad de Guadalajara (2015), and a Plant Biotechnology MSc in CINVESTAV (2018), focusing on the HSA-NPs synthesis and characterization for in vivo macrophage-targeted drug delivery via epigenome modification for therapeutic applications for atherosclerosis as a model. The results of this latter project were presented in the international Applied Nanotechnology and Nanoscience International conferences were celebrated in Rome (2017) and Berlin (2018). He has previous experience in undergraduate teaching in Science and English (2019–2021).  He received fellowships from CONACYT for an MSc and PhD studies.
Dr. Pavel H. Lugo-Fabres is a medical doctor with a Master's in Marine Biotechnology and a Ph.D. in Life Sciences. His research interests include pathophysiological models, organoids, 3D cell culture, and antibodies. Since 2019, he has been a researcher in the Medical and Pharmaceutical Biotechnology Unit at CIATEJ, located in Guadalajara, Mexico, and is a member of the Mexican National System of Researchers at level 1.
Tanya Amanda Camacho-Villegas is a researcher for Mexico in the Medical and Pharmaceutical Biotechnology Unit, CIATEJ, A.C., located in Guadalajara, Jalisco, Mexico (2014-present). She is a member of the Mexican National System of Researchers, level I. She works in recombinant protein design, cloning, and production (batch and bioreactor scale). She specializes in phage display for the isolation of single-domain antibodies such as vNARs or peptide isolation with diagnostic applications. Recently, she used the vNAR as an immuno-carrier for NPs for theranostics applications for breast cancer and glioblastomas as models. She has received a BSc in Biology from the Science Faculty, UABC (2004) and a Marine Biotechnology MSc in CICESE (2007), focusing on the selection and validation of vNARs with anti-cytokines properties as candidates for TNFalpha and VEGF165 neutralizing in human disorders. She has received a PhD in Molecular Ecology and Biotechnology from the Marine Science Faculty at UABC (2012). She received a distinction in the PhD dissertation and fellowships from CONACYT for MSc, PhD, and postdoc studies. She was the leader of four projects related to biotechnology companies. She was the author of patents related to vNAR as anti-cytokines or immuno-carriers for drug delivery.
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