Author Biographies

Adam J. de Smith is an Assistant Professor in the Center for Genetic Epidemiology in the Department of Population and Public Health Sciences at the USC Keck School of Medicine and is a member of the USC Norris Comprehensive Cancer Center. He received his Ph.D. in Human Genetic Variation from Imperial College London in 2010. He is a genetic epidemiologist with a research focus on identifying the causes of acute lymphoblastic leukemia (ALL), the most common childhood cancer. He leads studies investigating the role of common and rare genetic variants in ALL etiology, with a particular interest in elucidating the increased ALL risk in Hispanic/Latino children. He also leads a study of leukemia in children with Down syndrome, the International Study of Down Syndrome Acute Leukemia (IS-DSAL), investigating genetic and epigenetic variation associated with the risk of DS-ALL. In addition, he is co-PI of the NIH-funded ReCord Study, which is investigating the early-life origins of childhood leukemia through comprehensive backtracking of leukemia-causing mutations in cord blood.
Logan G. Spector is a Professor at the Department of Pediatrics, the Division Director of Epidemiology and Clinical Research, and a Faculty Member of the Brain Tumor Program, University of Minnesota. He received his Ph.D. in Epidemiology in 2002 from Emory University. After a year as a National Cancer Institute-funded postdoctoral fellow at the University of Minnesota, he joined the faculty as Assistant Professor of Pediatrics in the Division of Epidemiology/Clinical Research at the University of Minnesota. His research focuses on the causes of childhood cancer with a focus on childhood leukemia, bone sarcomas, and hepatoblastoma. His work includes both traditional and genetic epidemiologic approaches. He works in collaboration with colleagues and trainees locally, nationally, and internationally through the University of Minnesota, the Children's Oncology Group, and the Childhood Cancer and Leukemia International Consortium (CLIC). In addition, he collaborates with departmental colleagues in cardiology, rheumatology, and infectious diseases to study other pediatric outcomes. He is the immediate past Chair of the Children's Oncology Group Epidemiology Committee; a former standing member of the NIH Cancer, Cardiovascular, and Sleep Epidemiology panel B study section; and an ad hoc reviewer for many journals. Currently, he is Chair of CLIC, which pools epidemiologic studies of pediatric cancers from across the world to better ascertain their causes.
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