Author Biographies

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Fahd Al-Mulla is a Professor and Consultant, currently heading the Molecular Pathology and Genomic Medicine department at Kuwait University. He is also the Chief Scientific Officer and Head of the Department of Genetics and Bioinformatics at the Dasman Diabetes Institute. His research activities focus on cancer and diabetes. His research led to the identification of two novel metastasis suppressor genes, Carbonyl Reductase and Raf Kinase Inhibitory Proteins, which he and his team characterized further and determined their therapeutic roles in cancer. Fahd’s work is now focused on wound healing and angiogenesis defects in a genetic rat model of type II diabetes mellitus. He and his colleagues were not only able to ameliorate insulin resistance, but they also explained the precise molecular defects that predispose one to diabetes. Using wide genome array technology along with precise RNAi and protein inhibitors, he and his team enhanced wound closure and angiogenesis and mitigated cellular senescence in these animals. He received his Medical Doctorate and Ph.D. from Glasgow University. He is a Fellow of the Royal College of Physicians of Edinburgh. He has extensive experience in genomic-related technologies and intellectual property development. He currently holds seven patents related to diabetes, wound healing, and cancer. He also serves as Chair of the Evidence Group in the Global Genomic Medicine Collaborative.
Ashraf Al Madhoun earned his Ph.D. in Molecular Biology and Genetics from Crete University and the Institute of Molecular Biology and Biotechnology, Greece in 2000. He completed his postdoctoral training at the Biomedical Center in Uppsala, Sweden from 2000 to 2002, where he was promoted to Research Assistant Professor from 2002 to 2004. During this time, Dr. Madhoun focused his research on the biochemical and cellular characterization of thymidine analogs as prospective drugs for boron neutron capture therapy. In August of 2004, Dr. Madhoun moved to the University of Ottawa Heart Institute and the Faculty of Medicine, Canada, where he shifted his research to stem cell biology and regeneration. Since joining the Dasman Diabetes Institute in 2012, his research has focused on developmental biology and understanding the cellular signaling mechanisms that regulate stem cell differentiation into insulin-producing cells. Dr. Madhoun has developed an innovative protocol to generate glucose-responsive insulin-producing cells using stem cells. In collaboration with other scientists, he is also studying the functional role of the exercise-responsive meteorite-like hormone in the generation of thermogenic brown adipose tissues.
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