Author Biographies

Dr. Nancy S. Saad is a valued member of the research team at the Ohio State University Wexner Medical Center, holding both a Ph.D. in Cardiac Physiology and Cell Biology and an M.S. in Pharmaceutical Sciences. Since 2019, her role as a Research Scientist has centered on the study of the contractile and kinetic properties of the failing human myocardium, as well as the investigation of how various diseases and pharmacological agents affect these cardiac properties. Additionally, she is interested in studying the differences in contractile protein phosphorylation and expression at various ages in human myocardial tissue. Her research efforts also include investigating the impact of dysfunctional skeletal muscle relaxation on muscular dystrophy disease in mice. She is a member of several scientific societies, including the American Heart Association, Biophysical Society, Heart Failure Society of America, and Sigma Xi, the Scientific Research Honor Society. Her ultimate research objectives are to elucidate the molecular and cellular mechanisms that underlie human heart disease, particularly heart failure, and to develop new preventive and therapeutic measures against this global health issue, which is the leading cause of death in the United States and worldwide.
Dr. Mohammed A. Mashali is a Research Scientist specializing in Physiology and Cell Biology at the Ohio State University. His research endeavors are primarily focused on the mechanisms of myocardial contractility and kinetics in the context of heart failure progression. Additionally, Dr. Mashali investigates the impact of aging on the key mechanisms regulating intracellular calcium in the human heart. He is an active member of the American Heart Association, American College of Cardiology, and the Biophysical Society. Through his affiliations and research, Dr. Mashali aims to leverage these insights to significantly contribute to the development of innovative therapies aimed at preventing or treating age-related cardiovascular diseases.
Dr. Steven J. Repas received his MD from Wright State University Boonshoft School of Medicine in 2022. He is an emergency medicine resident at Wright State University (2022-2025). Dr. Repas's research topics mainly include heart failure, vitamin D, emergency medicine, trauma, EMS, and global health.
Dr. Paul M.L. Janssen completed his Ph.D. studies in Medical Physiology at Utrecht University in 1997. Since 2002, he has worked at the Ohio State University Medical Center as a Professor. Prior to this, he accepted a postdoctoral fellowship at the Albert-Ludwigs University and Georg-August University in Germany. His current research interest is mainly focused on the mechanisms that govern and impact cardiac relaxation in health and disease. He is multiple-awarded and a member of several societies, including the American Physiological Society, the Biophysical Society, and the International Society for Heart Research. He has 243 publications with 9332 citations and an h-index of 51 (Scopus, 24 November 2023).
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