Protein TRAF6

URN urn:agi-llid:7189
Total Entities 0
Connectivity 2646
Name TRAF6
Description TNF receptor-associated factor 6, E3 ubiquitin protein ligase
Notes The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins are associated with, and mediate signal transduction from, members of the TNF receptor superfamily. This protein mediates signaling from members of the TNF receptor superfamily as well as the Toll/IL-1 family. Signals from receptors such as CD40, TNFSF11/RANCE and IL-1 have been shown to be mediated by this protein. This protein also interacts with various protein kinases including IRAK1/IRAK, SRC and PKCzeta, which provides a link between distinct signaling pathways. This protein functions as a signal transducer in the NF-kappaB pathway that activates IkappaB kinase (IKK) in response to proinflammatory cytokines. The interaction of this protein with UBE2N/UBC13, and UBE2V1/UEV1A, which are ubiquitin conjugating enzymes catalyzing the formation of polyubiquitin chains, has been found to be required for IKK activation by this protein. This protein also interacts with the transforming growth factor (TGF) beta receptor complex and is required for Smad-independent activation of the JNK and p38 kinases. This protein has an amino terminal RING domain which is followed by four zinc-finger motifs, a central coiled-coil region and a highly conserved carboxyl terminal domain, known as the TRAF-C domain. Two alternatively spliced transcript variants, encoding an identical protein, have been reported. [provided by RefSeq, Feb 2012]
Primary Cell Localization Cytoplasm
ObjectType Protein

Pathway Osteoarthritis
Fatty Acids Block TLR Signaling in Enteroendocrine Cell
I-cell: CCK-8 Secretion and Regulation of Eating Behavior
Toll-like Receptors Act through MYD88-TIRAP Signaling
Antiviral Signaling through Pattern Recognition Receptors
Toll-like Receptors Act through MYD88 Signaling
TLR4 Signaling in Leukocytes
T-Cell Dependent B-Cell Activation
T-Cell Independent B-Cell Activation
V(D)J Recombination Activation
Immunoglobulin Class-Switch Recombination Activation
T-Cell Maturation (Hypothesis)
CD8+ T-Cell Activation
Th1-Cell Differentiation
Treg-Cell Differentiation
Th2-Cell Differentiation
T-Cell Receptor Signaling
Th17-Cell Differentiation
Toll-like Receptors in Sterile Inflammation
Toll-like Receptor Independent Sterile Inflammation
MC1R in anti-Inflammatory Signaling
Prostaglandin E2 Receptor Signaling in Neurons
Basophil Activation
Eosinophil Survival by Cytokine Signaling
Mast-Cell Activation without Degranulation through TNFSF8 Signaling
Mast-Cell Activation via IgE Signaling
Mast-Cell Activation without Degranulation
Mast-Cell Activation without Degranulation through IL33/IL1RL1 Signaling
Mast-Cell Activation without Degranulation through IL1R1 and TLR Signaling
Macrophage M1 Lineage
CD16/CD14 Proinflammatory Monocyte Activation
AHR Signaling in M1 Macrophages Function
anti-Inflammatory Function of Macrophage M2 Lineage
AXL Receptor Inhibits Macrophages and Dendritic Cells Function
Neutrophil Recruitment and Priming
Negative Acute Phase Proteins Synthesis
Positive Acute Phase Proteins Synthesis
Vascular Endothelial Cell Activation by Cytokines
Vascular Endothelial Cell Activation by Blood Coagulation Factors
Adipokines Production by Adipocyte
GFs/TNF -> Ion Channels
IL1B Expression Targets -> Nociception
Circadian Clock Genes in Suprachiasmatic Nuclei Neurons
Proteins Involved in Atherosclerosis
Scavenger Receptor OLR1 in Inflammation Related Endothelial Dysfunction
Dendritic Cells Function in Atherosclerosis
RAGE/AGER and S100 Proteins in Cardiovascular Injury
Th1-Cells Activation and Proliferation in Atherosclerosis
Myocardial Infarction
MAVS in Antiviral Innate Immune Response in Myocarditis
Lymphocyte Mediated Myocardial Injury in Myocarditis
Toll-like Receptors (TLR) in Antiviral Innate Immune Response
Inflammatory Reaction in Acne Vulgaris
Keratinocyte Proliferation in Acne Vulgaris
Atopic Dermatitis Onset
Mast-Cells Activation in Atopic Dermatitis
IL17 Signaling in Psoriasis
Dendritic Cells Function in Psoriasis
Apoptotic Keratinocytes Clearance Recession in Systemic Lupus Erythematosus
Dendritic Cell Activation in Systemic Lupus Erythematosis
Th17-Cell Function in Systemic Lupus Erythematosus
B-Cell Activation in Systemic Lupus Erythematosus
Th2-Cell Function in Systemic Lupus Erythematosus
Neutrophil and Macrophage Function in Systemic Lupus Erythematosus
Acute Cytotoxic CD8+T-Cell Response against Melanocytes
Vitiligo
T-Cell Cytotoxic Response against Melanocytes in Vitiligo
Humoral Immunity in Vitiligo
Treg-Cell Function in Diabetes Mellitus Type 1
Natural Killer T-Cell Roles in Diabetes Mellitus Type 1
non-Suppressive Treg-Cell in Diabetes Mellitus Type 1
Plasmacytoid Dendritic Cell in Diabetes Mellitus Type 1
TLR2 Signaling in Treg-Cell in Type 1 Diabetes (Animal Model)
Toll-like Receptors in beta-Cell
Peripheral Tolerance to Autoantigens Recession in Diabetes Mellitus Type 1
TLR7 and TLR9 in Plasmacytoid Dendritic Cell
Conventional Dendritic Cell Role in Diabetes Mellitus Type 1
Treg-Cell Activation in Diabetes Mellitus
Insulin Resistance in Myocytes Induced by Obesity
Hepatic Stellate Cells in non-Alcoholic Fatty Liver Disease
beta-Cell Destruction through Cytokines in Diabetes Mellitus
beta-Cell Destruction in Diabetes Mellitus Type 1
Bone Remodeling in Hyperthyroidism
Adipokines Production by Adipocyte Impaired in Obesity
CD4+T-Cell Response in Celiac Disease
Celiac Disease
Crohn's Disease
Dendritic Cell Dysfunction in Crohn's disease
Dendritic Cell Function in Ulcerative Colitis
Epithelial Cell in the Innate Immune Response in Ulcerative Colitis
Nicotine anti-Inflammatory Effect in Ulcerative Colitis
Th2-Cell Function in Ulcerative Colitis
T-Cell Cytotoxic Response in Ulcerative Colitis
Antiphospholipid Antibodies in Endothelial Cell
B-Cell Chronic Lymphocytic Leukemia
Diffuse Large-B-Cell Lymphoma
Diffuse Large-B-Cell Lymphoma ABC Subtype
Follicular Lymphoma
Hodgkin Lymphoma
Mantle Cell Lymphoma
mTOR/NF-kB/BCR Signaling Disregulation in Mantle Cell Lymphoma
Mucosa-Associated Lymphoid Tissue (MALT) Lymphoma
Splenic Marginal Zone Lymphoma
TNFR/NF-kB Classical Pathway in Multiple Myeloma Plasma Cells
Osteoclast Activation in Multiple Myeloma
Multiple Myeloma
Proteins Involved in Multiple Myeloma
Antiphospholipid Antibodies and Endothelial Cell Interaction
T-Cell Acute Lymphoblastic Leukemia
Eosinophil Survival in Asthma
Il17 Signaling Related Neutrophilia in Asthma
IL33 Signaling Related Eosinophilia in Asthma
TSLP Signaling in Bronchial Epithelial Cell in Asthma
IL17F Signaling in Bronchial Epithelial Cell in Asthma
Club-Cell Role in Asthma
Basophil Activation in Asthma
Antigen-Presenting Cell Role in Asthma
B-Cell Mediated IgE Production in Asthma
Th17-Cell Differentiation in Asthma
Th2-Cell Response in Asthma
Mucin Production in Goblet Airway Epithelial Cells
CFTR Facilitates Oxidative Stress in Airway Epithelium in CF
Airway Epithelial Cell Dysfunction
CFTR Expression in Epithelial Cells (Class I Mutations)
Osteoclast Activation in Gout
Neutrophil Recruitment in Sinovium in Gout
Monocytes Function in Gout
Hyper IgM Syndrome
TNF and IL1B Induce Metalloproteinase Synthesis in Osteoarthritis
IL1B Induced Arthralgia
Dendritic Cell Dysfunction in Psoriatic Arthritis
Th17-Cell and Th1 Immune Responsein Psoriatic Arthritis
Osteoclast Activation in Psoriatic Arthritis
Synovial Fibroblast Activation in Psoriatic Arthritis
Keratinocyte Activation in Psoriatic Arthritis
PTPN22 Role in Rheumatoid Arthritis
Osteoclast Activation in Rheumatoid Arthritis
Synovial Fibroblast Activation by Citokines in Rheumatoid Arthritis
TLR2 Induced Synovial Fibroblast Activation in Rheumatoid Arthritis
Autocrine Cytokine/Chemokine Loops in Systemic Scleroderma
B-Cells Function in Systemic Scleroderma
Th2-Cells Function in Systemic Scleroderma
Dentin Formation Disruption
Th17-Cell Numbers Reduction in HIV
CD4+ T-Cell Function Decline in HIV
CD4+ T-Cell Death in HIV
Toll-like Receptors (TLR) in Periodontitis
IL1 Receptor Antagonist (IL1RN) Deficiency (DIRA)
PAPA Syndrome
TNF Receptor Associated Periodic Syndrome
Mevalonate Kinase Deficiency
Blau Syndrome
IL36 Receptor Antagonist (IL1F5) Deficiency (DITRA)
Cryopyrin (NLPR3) Associated Periodic Syndromes
Familial Cold Autoinflammatory Syndrome 2
Familial Mediterranean Fever
Majeed Syndrome
Gluten Impact on Neuronal System (Hypothesis)
Osteoclasts Function in Osteopetrosis
Proteins Involved in Osteopetrosis
Osteoclast Activation in Postmenopause
Microglia Activation in Alzheimer's Disease
HMGB1 and IL1B in Neuroinflammation
Growth Factor Signaling in Neuroblastoma
Neuroblastoma
Microglia Activation in Parkinson's Disease
Subepithelial Fibroblasts in Middle Ear Cholesteatoma
Cholesteatoma
HPV E6 and E7 Induced Disruption of TNFR/NF-kB Signaling in Keratinocytes
Neurotrophic Factor Deprivation in Retinal Ganglion Cell Death
Cytokines Trigger Otitis Media
MUC5AC Expression by NTHi and S. Pneumoniae
Immune System Role in Otitis Media
Alveolar Macrophage Negative Regulation Declined in COPD
Alveolar Macrophages Dysfunction in COPD
T-Cell Cytotoxic Activation
Alveolar Epithelial Cell Dysfunction in COPD
Mucin Hyperproduction in Goblet and Mucous Cells
Endothelial Cell Dysfunction in Glomerulonephritis
Toll-like Receptors in Pyelonephritis
Endothelial Cell Dysfunction in Pyelonephritis
CD38/CD19 -> JUN/FOS/NF-kB Signaling in B-cell Proliferation
B-Cell Receptor -> NF-kB Signaling
TLR -> ARRB2/NF-kB Signaling
gamma Globulins Expression Targets
CD22 -> NF-kB Expression Targets
CD72 -> STAT Expression Target
CD8 -> STAT Expression Targets
CD80 -> STAT Expression Targets
CD86 -> STAT Expression Targets
PECAM1 Expression Targets
NFKB Canonical Signaling Activation in Cancer
NFKB Non-Canonical Signaling Activation in Cancer
STAT3 and NFkB Activate Inflammation-Induced Tumorigenesis
IL23A and IL17A Provoke Cancer-Associated Inflammation
TGFB Signaling activation by Blocking of Tumor Suppressors
NFKB Signaling Activation by Blocking of Tumor Suppressors
TGFB Family in Epithelial to Mesenchymal Transition in Cancer
IDO1 in Cancer Immune Escape
IFNLR1-> STAT/NFKB Signaling
IL1R -> STAT3 Signaling
IL1R -> NF-kB Signaling
IL16 -> NF-kB Expression Targets
CD40 -> Expression Targets in Lymph Node
NGF -> SMAD3/NF-kB Expression Targets
NGF -> AP-1/TP53/MYC Expression Targets
NGF -> FOXO/MYCN/ELK-SRF Expression Targets
BDNF Expression Targets
NTF3 Expression Targets
NTF4 Expression Targets
NGF -> CREB/CEBPB/MEF2A Expression Targets
PDCD1 -> NF-kB Expression Targets
DDR1 -> NF-kB Signaling
Collagen -> NF-kB Expression Targets
JNK/MAPK Signaling
TGF-beta Signaling
P38 MAPK/MAPK14 Signaling
NF-kB non-Canonical Signaling
ERK5/MAPK7 Signaling
NF-kB Canonical Signaling
TCR -> NF-kB Expression Targets
T-Cell Receptor -> AP-1 Signaling
T-Cell Receptor -> NF-kB Signaling
CD72 -> AP-1 Expression Targets
CD40LG -> NF-kB/ELK/SRF -> CREB/NFATC Expression Targets
TNFSF13 Expression Targets
TNFSF13B Expression Targets
EDA Expression Targets
EctodysplasinR -> NF-kB Signaling
EctodysplasinR -> AP-1 Signaling
TNFR -> CREB/ELK-SRF Signaling
TNFR -> AP-1/ATF/TP53 Signaling
TNFRSF5/13B -> NFATC1 Signaling
NGFR -> AP-1/CEBPB/CREB/ELK/SRF/TP53 Signaling
TNFRSF5/6 -> RB1/E2F Signaling
NGFR -> NF-kB Signaling
EctodysplasinR -> LEF1 Signaling
TNFR -> NF-kB Signaling
NGFR -> MEF Signaling
TLR4 -> AP-1 Expression Targets
TLR5 Expression Targets
TLR7 Expression Targets
TLR4 -> AP-1/EGR1/HIF1A Expression Targets
TLR1 -> 2/6 Expression Targets
IL1B Expression Targets
TLR4 -> NF-kB/IRF Expression Targets
IL1A Expression Targets
TLR9 Expression Targets
TLR4/5/7/9 -> NF-kB Signaling
TLR1/2/6 -> NF-kB Signaling
TLR -> AP-1 Signaling
pathway 4
Model of PPARG signaling in psoriasis
Model of PPARG related pathways in psoriasis (short version)
New Pathway (3)
sars-cov no binding
dsRNA induces innate immunity and INFs in alveolar cells
IFN signaling in alveolar cells
Innate immunity in Leukocytes
AGER feed forward loop in innate immunity
Dendritic Cell Activation in COVID19
1_Inflammation in keratinocytes in the pathology of acne
2_Acute phase initiation in atopic dermatitis
2_Interleukin-17 and interleukin-22 signaling in psoriasis
1_The onset of atopic dermatitis
1_TNF and IL1B provoke ECM degradation in osteoarthritis
1_Osteoclast-mediated bone resorption in postmenopausal women
1_Osteoclast functional impairment in osteopetrosis
2_Chondrocyte death in osteoarthritis
1_The role of Toll-like receptors in pyelonephritis
2_The role of endothelial cells in pyelonephritis
3_Role of neurotrophic factor deprivation in retinal ganglion cell death
1_Insufficient activation of immune response in the middle ear epithelium cells in otitis media
2_Pathogens stimulate mucins expression in the middle ear
3_Arterial wall inflammation and calcification in atherosclerosis
1_Cigarette smoke causes dysfunction and production of inflammatory mediators in alveolar epithelial cells
3_Role of alveolar macrophages in pulmonary tissue destruction in COPD
1_Th2 cell response in asthma
3_2_Regulation of airway surface liquid (ASL) thickness
3_1_Mucus accumulation in asthma
2_2_Eosinophilia and neutrophilia in asthma: eosinophil apoptosis
4_Mucin hyperproduction in goblet and mucous cells in COPD
2_Paneth cell dysfunction in Crohn's disease
1_Defects in response to pathogens in the gut promotes inflammation in Crohn's disease
2_Intestine epithelial cells drive immunological responses in ulcerative colitis
1_Intestine epithelial cell dysfunction in ulcerative colitis
2_Lipotoxicity in NAFLD
1_CD4+ T cell and epithelial cell response in celiac disease
6_p12I Viral protein promotes T-cell activation in HTLV-1 infection
5_Human papilloma virus E6 and E7 proteins promote epithelial cell proliferation
4_3_Insulin resistance: FFA-related insulin resistance
1_CFTR expression and degradation in epithelial cells in cystic fibrosis (class I-II mutations)
1_Antigen-presenting cells promote islet dysfunction and immune system activation in T1D
3_Islet beta-cell destruction in T1D
2_Neuron and Schwann cell death
Figure 4_Diabetes mellitus Type 1: conventional dendritic cell
Model of PPARG signaling in psoriais (tested)
Interleukin-17 and interleukin-22 signaling in psoriasis

Group other partners for SARS

MedScan ID 7189

LocusLink ID 7189
22034
311245
72304
99098

Alias OTTMUSP00000015480
C630032O20
MGC:3310
interleukin-1 signal transducer
AI851288
TNF receptor-associated factor 6, E3 ubiquitin protein ligase
RING-type E3 ubiquitin transferase TRAF6
TNF receptor-associated factor 6
LOC100048242
RING finger protein 85
RNF85
TNF receptor-associated factor VI
E3 ubiquitin-protein ligase TRAF6
TNF-alpha receptor-associated factor 6
RIKEN cDNA 2310003F17 gene
LOC100042930
C630032O20Rik
Tumor necrosis factor-alpha receptor associated factor 6
TRAF6
2310003F17Rik
Tumor necrosis factor receptor associated factor 6
2310003F17
tumor necrosis factor (TNF) receptor-associated factor 6
RP23-313G3.1
RIKEN cDNA C630032O20 gene
tumour necrosis factor receptor associated factor 6
tumour necrosis factor (TNF) receptor-associated factor 6
Putative interleukin 1 signal transducer
LOC222344
expressed sequence AI851288
Tnf receptor-associated factor 6 (predicted)

EC Number 2.3.2.27
6.3.2.-

GO ID 0042826
0031435
0047485
0043422
0019901
0031996
0005164
0031624
0061630
0031625
0004842
0008270
0038095
0007249
0007254
0002755
0050852
0042088
0000187
0007250
0032147
0019886
0045453
0048468
0006974
0071345
0071222
0001701
0070498
0031293
0043011
0043066
0000122
0045892
0001843
0070423
0042475
0001503
0030316
0051091
0043123
0043507
0051092
1901224
0002726
0042102
0043065
0045084
0032743
0045410
1904996
0031666
0045672
0031398
0048661
0045944
2000679
0070534
0051865
0016579
0000209
0051023
0070555
0002223
0034162
0002224
0035631
0005938
0005737
0009898
0005829
0010008
0005811
0005634
0048471
0005886
0032991
0046872
0016740
0009887
0046849
0019221
0006955
0002376
0016567
0043122
0042981
0007165
0005622
0045087
0051403
0016874
0002756
0008624
0005515
0035666
0008063
0043234
0048011
0034166
0070740
0070736
0070735
0038123
0070738
0038124
0070737
0070739
0004871
0031965
0005739
0097190
0043773
0043774
0005730
0050870
0006915
0034146
0006916
0035872
0034142
0034134
0034138
0034130
0018169
0006461
0008766
0016564
0005624
0008152
0019941
0004872
0006512
0042591

KEGG ID hsa:7189
mmu:22034
rno:311245

MedLine Reference 15890643
16079148
10215628
10349636
10421844
11007897
11042159
11076861
11217851
11250893
11547829
11923871
11967542
11994463
12060722
12140561
12185073
12354380
12459498
12466851
12477932
12566447
12616498
12631284
12637570
12711536
12819136
12902324
12958312
14499111
14500659
14634083
14645259
14661019
14673102
14699584
15102471
15305292
15308666
15322147
15361868
15385464
15548667
15678102
15705807
15864310
15905851
16033648
16141072
16141073
16147974
16237096
16246731
16252010
16263713
16306937
16378096
16393988
16436380
16446357
16630834
16772369
16831874
16897814
16921377
17055451
17092936
8889548
8910514
10025951
10075662
10094049
10383454
10411888
10465784
10514511
10523862
10635328
10747026
10748240
10764746
10880535
10882101
10920205
11035039
11057907
11244088
11278268
11279055
11397809
11406619
11418661
11463333
11607847
11751921
11847341
11882293
11960013
12048196
12193732
12270937
12496252
12609980
12714497
12721283
12761501
12804775
12874243
12917691
12925853
14500648
14530355
14550571
14593105
14633987
14665433
14743216
14754897
14996708
15125833
15247281
15280356
15456887
15492226
15591054
15634933
15665823
15670770
16052631
16153868
16184196
16189514
16196101
16221674
16230348
16251197
16260598
16280329
16313339
16354686
16452479
16484229
16517750
16527194
16920630
16932746
8837778
9374458
9642260
9685412
9915784
9928991
10346818
10908663
11384837
15489334
16125763
16286016
17135271
17346928
17363736
17377523
17572386
9020361
9432981
9774460
9774977
16210631
17224624
17277780
17332487
17360955
17462996
17507094

Organism Homo sapiens {Organism urn:agi-taxid:9606}
Mus musculus {Organism urn:agi-taxid:10090}
Rattus norvegicus {Organism urn:agi-taxid:10116}
Homo sapiens
Mus musculus
Rattus norvegicus

Mouse chromosome position 2
2 E2

OMIM ID 602355

Rat chromosome position 3q31

Hugo ID 12036
HGNC:12036

Human chromosome position 11p12

Swiss-Prot Accession Q9Y4K3
Q9Y4K3.1
P70196
P70196.2
B5DF45
B5DF45.1
A6NKI7
A8KAB3
D3DR16
Q8NEH5
Q6P9M0
Q8BLV2
TRAF6_HUMAN
B5DF45_RAT
Q6P9M0_MOUSE

PIR ID S71821

GenBank ID NC_000011
NM_004620
NP_004611
NM_145803
NP_665802
XM_017018220
XP_016873709
AC009656
AC061999
AY228337
AAO38054
CH471064
EAW68119
EAW68120
EAW68121
EAW68122
AK128396
AK292978
BAF85667
BC031052
AAH31052
BI463192
BQ187062
DA855021
U78798
AAB38751
Q9Y4K3
NC_000068
NM_009424
NP_033450
NM_001303273
NP_001290202
AL929571
CH466519
EDL27656
EDL27657
AK009110
AK033718
AK040308
AK041172
BAC30850
AK051130
AK083275
AK155434
BAE33263
BC060705
AAH60705
BY131535
D84655
BAA12705
P70196
NC_005102
NM_001107754
NP_001101224
AC_000071
AABR07053106
AAHX01023904
CH473949
EDL79625
BC168921
AAI68921
FQ209645
B5DF45
CAM20505
XP_006234705
XM_006499156
AC_000024
AC_000143
NC_018922
ABM85318
AABR06025116
AAHY01019032
DQ891209
ABBA01060847
ABBA01060846
ABM82135
XP_006499219
AMYH02024607
DQ894392
XM_006234643
NT_009237
NW_925006
NW_001838022
AC_000054
CR590964
CR612801
NT_039207
NW_001030694
NW_001084813
NW_047657
Q6P9M0
XM_230377
XP_230377
XM_001079281
XP_001079281
XM_001479093
XP_001479143
XM_001479837
XP_001479887
BG916928
AI414846
AV377471
NW_000178
1651195
26334265
30580620
38173732
74206917
81911340
AI851288
119588525
119588526
119588528
123995433
1732426
21410269
28372409
30580642
119588527
123980612
123239824
148695709
148695710
149022731

Swiss-Prot ID TRAF6_HUMAN
TRAF6_MOUSE
TRAF6_RAT
B5DF45_RAT
Q6P9M0_MOUSE
D3DR16_HUMAN

Cell Localization Cytoplasm
Cell cortex
Nucleus
Lipid droplet
Cytoplasm, cell cortex

Ensembl ID ENSG00000175104
ENSP00000433623.1
ENST00000526995.6
ENSP00000337853.5
ENST00000348124.5
ENSMUSG00000027164
ENSMUSP00000004949.7
ENSMUST00000004949.7
ENSRNOG00000004639
ENSRNOP00000006148.4
ENSRNOT00000006148.5
ENST00000526995
ENSMUST00000004949
ENSP00000337853
ENSMUSP00000004949
ENST00000526995.5
ENSP00000433623
ENSRNOP00000006148
ENST00000348124
ENSRNOT00000006148

MGI ID MGI:108072
108072
2139081
1919554

RGD ID 1306853

Unigene ID Mm.292729
Rn.24348
Hs.591983
Rn.220435
Hs.444172
Mm.460024
Rn.106292
Mm.439908

Homologene ID 3395

IPI ID IPI00136488
IPI00222919
IPI00743663
IPI00363697
IPI00420463

Homo sapiens Chromosome position 11p12

Ensembl Transcript ID ENST00000348124
ENST00000313105
ENST00000526995

FunctionalClass protein binding
signal transducer
metal ion binding
receptor
zinc ion binding
ubiquitin-protein ligase

Mus musculus Chromosome position 2 E2
2

Rattus norvegicus Chromosome position 3q31

Ensembl Gene ID ENSG00000175104