Protein MAP3K5

URN urn:agi-llid:4217
Total Entities 0
Connectivity 2606
Name MAP3K5
Description mitogen-activated protein kinase kinase kinase 5
Notes Mitogen-activated protein kinase (MAPK) signaling cascades include MAPK or extracellular signal-regulated kinase (ERK), MAPK kinase (MKK or MEK), and MAPK kinase kinase (MAPKKK or MEKK). MAPKK kinase/MEKK phosphorylates and activates its downstream protein kinase, MAPK kinase/MEK, which in turn activates MAPK. The kinases of these signaling cascades are highly conserved, and homologs exist in yeast, Drosophila, and mammalian cells. MAPKKK5 contains 1,374 amino acids with all 11 kinase subdomains. Northern blot analysis shows that MAPKKK5 transcript is abundantly expressed in human heart and pancreas. The MAPKKK5 protein phosphorylates and activates MKK4 (aliases SERK1, MAPKK4) in vitro, and activates c-Jun N-terminal kinase (JNK)/stress-activated protein kinase (SAPK) during transient expression in COS and 293 cells; MAPKKK5 does not activate MAPK/ERK. [provided by RefSeq, Jul 2008]
Primary Cell Localization Cytoplasm
Class Protein kinase

Pathway Osteoarthritis
MTHFR Activity Regulation
Peripheral T-Cell Tolerance
Leukotriene Effect on Vascular Endothelial Cell Response
Basophil Activation
Mast-Cell Activation without Degranulation through TNFSF8 Signaling
Mast-Cell Activation without Degranulation
Mast-Cell Activation without Degranulation through IL33/IL1RL1 Signaling
Mast-Cell Activation without Degranulation through IL1R1 and TLR Signaling
Macrophage M1 Lineage
AXL Receptor Inhibits Macrophages and Dendritic Cells Function
Neutrophil Recruitment and Priming
Vascular Endothelial Cell Activation by Cytokines
Vascular Endothelial Cell Activation by Growth Factors
GFs/TNF -> Ion Channels
IL1B Expression Targets -> Nociception
Circadian Clock Genes in Suprachiasmatic Nuclei Neurons
Apoptosis
Cardiomyocyte Dysfunction
Dilated Cardiomyopathy
Cardiomyocyte Hypertrophy
Hypertrophic Cardiomyopathy
Myocardial Remodeling
Myocardial Infarction
Proteins Involved in Myocardial Ischemia
Inflammatory Reaction in Acne Vulgaris
Keratinocyte Proliferation in Acne Vulgaris
Mast-Cells Activation in Atopic Dermatitis
IL17 Signaling in Psoriasis
Th0-Cell Aberrant Activation in Systemic Lupus Erythematosus
Vitiligo
Apoptosis of Melanocyte in Vitiligo
Podocyte Dysfunction in Diabetic Nephropathy
Mesangial Cell Dysfunction in Diabetic Nephropathy
Oxidation of Fatty Acid in non-Alcoholic Fatty Liver Disease
Nitric Oxide Effects on beta-Cell
Apoptosis of Thyroid Cell in Hashimoto's Thyroiditis
Antiphospholipid Antibodies in Endothelial Cell
Osteoclast Activation in Multiple Myeloma
Antiphospholipid Antibodies and Endothelial Cell Interaction
SERPINA1 Associated Liver Damage
Hepatocellular Carcinoma
Growth Factor Signaling in Hepatocellular Carcinoma
Pancreatic Ductal Carcinoma
Growth Factor Signaling in Pancreatic Neoplasms
Pancreatic Neuroendocrine Tumors
TGFBR Signaling in Pancreatic Neoplasms
IL33 Signaling Related Eosinophilia in Asthma
CFTR Expression in Epithelial Cells (Class I Mutations)
Neutrophil Recruitment in Sinovium in Gout
TNF and IL1B Induce Metalloproteinase Synthesis in Osteoarthritis
Apoptosis of Chondrocyte
IL1B Induced Arthralgia
Synovial Fibroblast Activation in Psoriatic Arthritis
Synovial Fibroblast Activation by Citokines in Rheumatoid Arthritis
Apoptosis Block in Synovial Fibroblast
Autocrine Cytokine/Chemokine Loops in Systemic Scleroderma
FAS Mediated Apoptosis in Systemic Scleroderma
Apoptosis Block in Infected Cells
Diabetes Induced Periodontitis
IL1 Receptor Antagonist (IL1RN) Deficiency (DIRA)
TNF Receptor Associated Periodic Syndrome
IL36 Receptor Antagonist (IL1F5) Deficiency (DITRA)
ER Stress in Huntington Disease
Growth Factor Signaling in Neuroblastoma
Neuroblastoma
Proteins Involved in Amyotrophic Lateral Sclerosis
Crystallin alpha B (CRYAB) Suppresses Multiple Sclerosis
Proteins Involved in Breast Cancer Related to ESR1 Signaling Pathway
ESR1/ERBB Positive Luminal Breast Cancer
Breast Cancer
ESR1 Signaling in Breast Cancer
Endometrial Cancer
Endometrioid Endometrial Cancer
Clear Cell Endometrial Cancer and Papillary Serous Endometrial Cancer
Endometrioid Ovarian Carcinoma
Clear Cell Ovarian Carcinoma
High-Grade Serous Ovarian Carcinoma
Low-Grade Serous Ovarian Carcinoma
Ovarian Cancer
Mucinous Ovarian Carcinoma
Subepithelial Fibroblasts in Middle Ear Cholesteatoma
Androgen Receptor/Akt Signaling
ER Stress in Macular Degeneration
Steroids Induced Cataract
MYOC Associated Glaucoma
Neurotrophic Factor Deprivation in Retinal Ganglion Cell Death
Cytokines Trigger Otitis Media
Endothelial Cell Dysfunction in Glomerulonephritis
Podocyte Dysfunction in Glomerulonephritis
Mesangial Cell Dysfunction in Glomerulonephritis
Interstitial Fibroblasts in Pyelonephritis
Apoptosis of Renal Tubule Epithelial Cell in Pyelonephritis
Endothelial Cell Dysfunction in Pyelonephritis
CXCR4 -> ARRB1 Signaling
AGTR1 -> ARRB1/ARRB2 Signaling
Sialophorin -> CTNNB/MYC/TP53 Signaling
TGFB Signaling activation by Blocking of Tumor Suppressors
Apoptosis Block by Death Receptor Signaling in Cancer
Apoptosis Evasion in Cancer: Overview
Effector T-cell Inactivation in Cancer Immune Escape
IL1R -> NF-kB Signaling
Elevated Receptors -> Expression Targets in Lymph Node
NGF -> SMAD3/NF-kB Expression Targets
NGF -> AP-1/TP53/MYC Expression Targets
NGF -> FOXO/MYCN/ELK-SRF Expression Targets
BDNF Expression Targets
NTF3 Expression Targets
NTF4 Expression Targets
NGF -> CREB/CEBPB/MEF2A Expression Targets
TGFBR -> AP-1 Signaling
TGFBR -> CREB/ELK-SRF Signaling
TGFBR -> ATF/GADD/MAX/TP53 Signaling
TGFBR -> MEF/MYOD/MYOG Signaling
TNF-alpha/TNFRSF1A Signaling
JNK/MAPK Signaling
TGF-beta Signaling
P38 MAPK/MAPK14 Signaling
HRAS Signaling
TGFB3-TGFBR2 Expression Targets
TGFB2-TGFBR2 Expression Targets
TGFB1-TGFBR2 Expression Targets
FASLG Expression Targets
TNF -> NF-kB Expression Targets
TNFSF10 Expression Targets
LTA Expression Targets
TNFSF14 Expression Targets
TNF -> AP-1 Expression Targets
CD72 -> AP-1 Expression Targets
CD40LG -> NF-kB/ELK/SRF -> CREB/NFATC Expression Targets
TNFSF13 Expression Targets
TNFSF13B Expression Targets
TNF -> ELK-SRF Expression Targets
TNF -> CREB Expression Targets
TNF -> TP53/ATF Expression Targets
EDA Expression Targets
EctodysplasinR -> NF-kB Signaling
EctodysplasinR -> AP-1 Signaling
TNFR -> CREB/ELK-SRF Signaling
TNFR -> AP-1/ATF/TP53 Signaling
NGFR -> AP-1/CEBPB/CREB/ELK/SRF/TP53 Signaling
TNFRSF5/6 -> RB1/E2F Signaling
NGFR -> NF-kB Signaling
TNFR -> NF-kB Signaling
NGFR -> MEF Signaling
TNFRSF6 -> DDIT3 Signaling
TNFRSF6 -> HSF1 Signaling
TNFRSF1A -> AP-1/ATF/TP53 Signaling
TNFRSF1A -> CREB/ELK-SRF Signaling
IL1B Expression Targets
IL1A Expression Targets
ER Stress (Unfolded Protein Response)
ROS in Angiotensin Mediated Cardiovascular Remodeling and Hypertrophy
1_Inflammation in keratinocytes in the pathology of acne
2_Interleukin-17 and interleukin-22 signaling in psoriasis
1_TNF and IL1B provoke ECM degradation in osteoarthritis
1_Osteoclast-mediated bone resorption in postmenopausal women
2_Chondrocyte death in osteoarthritis
2_The role of endothelial cells in pyelonephritis
3_The role of interstitial fibroblasts in pyelonephritis
3_Mesangial cell dysfunction in glomerulonephritis
2_Podocyte dysfunction in glomerulonephritis
3_Role of neurotrophic factor deprivation in retinal ganglion cell death
2_MYOC-associated glaucoma
3_Endoplasmic reticulum stress in age-related macular degeneration
2_Cardiomyocyte hypertrophy
3_Cardiomyocyte dysfunction unrelated to cell junctions in ARVD
2_Cigarette smoke and inflammation cause alveolar epithelial cell death in COPD
2_Lipotoxicity in NAFLD
2_HIV - induced depletion of CD4+ T-cells
4_2_Insulin resistance: inflammation-related insulin resistance
4_3_Insulin resistance: FFA-related insulin resistance
2_SERPINA1-associated liver damage
2_Neuron and Schwann cell death
HRAS->RAF->MAPK1/3
Interleukin-17 and interleukin-22 signaling in psoriasis

Source curated

MedScan ID 4217
365057
293015

LocusLink ID 4217
26408
365057
293015
17273
320994
537380
555703
336299
373122
555773
326408

Alias MAPKKK5
MAPK/ ERK kinase kinase V
7420452D20
mitogen-activated protein kinase kinase kinase V
MGC141518
RP3-325F22.4
MAP kinase kinase kinase 5
ASK1
MEK kinase 5
OTTMUSP00000040576
MGC141519
OTTHUMP00000017275
LOC270672
Map3k5
MAP/ERK kinase kinase 5
mitogen activated protein kinase kinase kinase 5
RGD1306565
apoptosis signal regulating kinase
MAP/ERK kinase kinase V
MAPK/ ERK kinase kinase 5
7420452D20Rik
apoptosis signaling-regulating kinase 1
Apoptosis signal- regulating kinase 1
MEKK5
ASK I
Apoptosis signal- regulating kinase I
RIKEN cDNA 7420452D20 gene
MEK kinase V
ASK-1
MAPK/ERK kinase kinase 5
MEKK 5
apoptosis signal-regulating kinase 1
mitogen-activated protein kinase kinase kinase 5
ASK
apoptosis signal regulating kinase 1
hypothetical protein LOC270672
similar to ASK I
similar to ASK1
Rtc I
scaffold
Resistance to Tongue Carcinomas QTL I
fj62c10
chromosome
LOC555773
Map3k5_predicted
Resistance to Tongue Carcinomas QTL 1
similar to mitogen-activated protein kinase kinase kinase 5
Ttr1
wu:fj62c10
Rtc1

EC Number 2.7.11.25
2.7.1.-

GO ID 0005524
0004709
0000287
0019904
0042803
0004672
0019901
0019903
0004674
0007254
0000165
0007257
0000186
0097190
0034198
0070301
1902170
0071356
0072577
0045087
0070059
0008631
0038066
0046330
0043507
0043065
0010666
0043280
0045663
1901216
1900745
0045893
1904707
0097300
0006468
0034976
0002931
0051403
0016032
0042060
1990604
0005829
0009897
1902911
0032991
0016301
0046872
0000166
0016740
0000187
0006915
0002376
0016310
0001934
0010941
0005737
0005783
0008656
0006919
0016772
0005622
0019048
0006950
0010421
0008624
0044419
0010952
0043281
0005515
0042802
0005575
0004713
0004706
0031434
0046982
0007256
0046777
0051291
0005938
0005634

KEGG ID hsa:4217
mmu:26408
rno:365057

MedLine Reference 12050113
12869527
15629441
16006035
16316999
16648474
16762504
16891268
17015265
10349636
11042159
11076861
11217851
11266364
11959862
12215209
12391142
12466851
12477932
12724324
14551246
14665690
14668338
15467832
15767678
15864310
15938714
15953587
15976330
16109778
16141072
16141073
16400028
16449798
16731828
9367868
10411906
10523862
10734135
10921914
11003656
11090355
11096076
11154276
11278289
11336675
11356842
11416155
11427728
11493600
11689443
11920685
12077134
12089063
12189133
12244106
12372597
12473108
12482984
12543931
12556535
12566458
12697749
12813029
12819028
12912994
12968034
14688258
14761963
15023544
15210709
15218033
15246877
15310755
15328343
15670787
15701637
15755722
15782121
15843568
15864780
15866172
15925322
16476732
16512785
16515547
16532036
16636664
16644673
8940179
8974401
9465908
9564042
9651337
9743501
9774977
9875215
10917738
12618376
12641569
11298454
14574404
15094778
15489334
17210579
17220297
17244475
17325029
17331470
17389591
17456047
17543279
17068291
17219248
17389227
17522316
17602894
17646574

Organism Homo sapiens {Organism urn:agi-taxid:9606}
Mus musculus {Organism urn:agi-taxid:10090}
Rattus norvegicus {Organism urn:agi-taxid:10116}
Homo sapiens
Mus musculus
Rattus norvegicus
Bos taurus
Danio rerio
Human

Mouse chromosome position 10
10 A3

OMIM ID 602448
OMIM:602448
61399

Rat chromosome position 1p12

Hugo ID 6857
HGNC:6857

Human chromosome position 6q23.3
6q22.33

Swiss-Prot Accession Q99683
Q99683.1
O35099
O35099.3
A6NIA0
B4DGB2
Q5THN3
Q99461
Q14AY5
Q59GL6
Q14AY4
Q8CC79
M3K5_HUMAN
Q14AY5_MOUSE

PIR ID JC5778

GenBank ID NC_000006
XM_017010875
XP_016866364
XM_017010872
XP_016866361
XM_017010873
XP_016866362
NM_005923
NP_005914
XM_017010877
XP_016866366
XM_017010874
XP_016866363
XM_017010871
XP_016866360
XM_017010870
XP_016866359
XM_017010876
XP_016866365
XM_011535839
XP_011534141
NG_011965
AL024508
AL121933
AY605043
AAT52164
CH471051
EAW47942
KT584492
AB209093
BAD92330
AK293953
BAG57328
AK294507
BAG57723
AK310942
BC054503
AAH54503
BC088829
AAH88829
D84476
BAA12684
U67156
AAC50894
Q99683
NC_000076
XR_001779529
XM_006512739
XP_006512802
NM_008580
NP_032606
AC158620
AC158621
AC168883
AC171277
CH466562
EDL03445
AB006787
BAA23648
AK033726
BAC28449
AK078668
BC116627
AAI16628
BC116628
AAI16629
BC133697
AAI33698
O35099
NC_005100
NM_001277694
NP_001264623
AC_000069
AABR07000495
AABR07000496
AABR07000497
AABR07000498
AABR07000499
AABR07000500
AAHX01001718
AAHX01001719
AAHX01001720
AAHX01001721
AAHX01001722
AAHX01001723
AAHX01001724
AAHX01001725
AAHX01001726
AAHX01001727
AAHX01001728
AAHX01001729
AAHX01001730
AAHX01001731
AAHX01001732
AAHX01001733
AAHX01001734
AAHX01001735
AAHX01001736
CH473994
EDL93792
XM_011535838
XP_011534140
XM_011535837
XP_011534139
NC_018917
AMYH02014559
AMYH02014560
AMYH02014561
AC_000032
AAHY01083852
AAHY01083853
AAHY01083854
AAHY01083855
AAHY01083856
AAHY01083857
AAHY01083858
AAHY01083859
AAHY01083860
AAHY01083861
AAHY01083862
AAHY01083863
AAHY01083864
AAHY01083865
AAHY01083866
AAHY01083867
AAHY01083868
AAHY01083869
AAHY01083870
AAHY01083871
XM_008758622
XP_008756844
XM_005266990
XP_005267047
XM_006715482
XP_006715545
XM_005266991
XP_005267048
XM_005266992
XP_005267049
AC_000138
ABBA01025825
ABBA01025826
AABR06000786
AABR06000787
AABR06000788
AABR06000789
AABR06000790
AABR06000791
AABR06000792
AABR06000793
AABR06000794
AABR06000795
CAI20176
CAI15470
XR_145729
XR_146724
NT_025741
NW_923184
NW_001838990
AC_000049
Q59GL6
NT_039492
NW_001030408
Q14AY4
Q14AY5
Q8CC79
NW_032785
XP_001006040
XM_001006040
XM_913629
Q5THN3
109730385
109733254
123782812
123792789
26329421
68533198
81877629
82654957
119568327
1679668
32452016
55957178
56202652
57033166
62087766
66391167
6685617
74741299
NT_086697
NW_047545
XM_218780
XP_218780
XP_918722
NC_007307
NW_001495597
XM_617542
XP_617542
AW282104
AW305675
56208086
56311422
AI497484
AL922223
BX248523
BX545848
CAI21268
CAI29402
123913850
82196411
DU645016
NC_007131
NW_001512062
Q5PNR2
Q5RHC1
XM_678295
XP_683387
56311423
CAI29403
126631249
148671498
5174547
57033165
1805500
51465807
1679667
37551196
1805499
21536459
6678795
6678796
2653433
2653434
26098027
NT_039491
26329420
34193967
6685611
34852815
51765492
34852812
34852811

Swiss-Prot ID M3K5_HUMAN
M3K5_MOUSE
Q14AY5_MOUSE

Cell Localization Cytoplasm
Endoplasmic reticulum

Ensembl ID ENSG00000197442
ENSP00000351908.4
ENST00000359015.5
ENSMUSG00000071369
ENSMUSP00000093485.3
ENSMUST00000095806.9
ENSRNOG00000031700
ENSRNOP00000051338.5
ENSRNOT00000051496.6
ENSP00000351908
ENST00000359015
ENSMUSP00000093485
ENSMUST00000095806
ENSRNOP00000051338
ENSRNOT00000051496

MGI ID MGI:1346876
1346876
1101761
2445207

RGD ID 1306565
1306431
61399

Unigene ID Hs.186486
Mm.6595
Rn.232064
Rn.108921
Hs.151988
Bt.31917
Dr.122363
Dr.16458
Dr.27055

Homologene ID 38114

Shape Sickle-vertex

IPI ID IPI00412433
IPI00126589
IPI00890883
IPI00479216
IPI00748581
IPI00894869
IPI00895076
IPI00894925

Chromosome position 6q22.33
1p12
10 A3

Microarray ID 99855_at
203837_at
A_51_P300986
ab006787_at
U67156
MA206
U67156_at
A_23_P134125
A_14_P104796
1327_s_at
rc_aa057432_s_at
A_14_P126311
203836_s_at
OH8272
A_14_P112751
A_14_P118658
A_14_P110978
CA078
1421340_at

Homo sapiens Chromosome position 6q22.33

Ensembl Transcript ID ENST00000359015

ENSEMBL ENSG00000197442

FunctionalClass MAP kinase kinase kinase
caspase activator
identical protein binding
protein binding
ATP binding
kinase
magnesium ion binding
metal ion binding
nucleotide binding
protein kinase
protein serine/threonine kinase
transferase
protein self binding
protein homodimerization
protein-tyrosine kinase

Hugo Symbol MAP3K5

Bos taurus Chromosome position 9

Mus musculus Chromosome position 10 A3

KEGG pathway MAPK signaling pathway

Rattus norvegicus Chromosome position 1p12

Ensembl Gene ID ENSG00000197442

ProteinAtlas NormalTissue Tissue: adrenal gland; Cell type: glandular cells; Level: Moderate; Expression type: Staining; Reliability: Uncertain
Tissue: appendix; Cell type: glandular cells; Level: Negative; Expression type: Staining; Reliability: Uncertain
Tissue: appendix; Cell type: lymphoid tissue; Level: Weak; Expression type: Staining; Reliability: Uncertain
Tissue: bone marrow; Cell type: hematopoietic cells; Level: Weak; Expression type: Staining; Reliability: Uncertain
Tissue: breast; Cell type: glandular cells; Level: Negative; Expression type: Staining; Reliability: Uncertain
Tissue: bronchus; Cell type: respiratory epithelial cells; Level: Moderate; Expression type: Staining; Reliability: Uncertain
Tissue: cerebellum; Cell type: cells in granular layer; Level: Negative; Expression type: Staining; Reliability: Uncertain
Tissue: cerebellum; Cell type: cells in molecular layer; Level: Negative; Expression type: Staining; Reliability: Uncertain
Tissue: cerebellum; Cell type: Purkinje cells; Level: Negative; Expression type: Staining; Reliability: Uncertain
Tissue: cerebral cortex; Cell type: glial cells; Level: Negative; Expression type: Staining; Reliability: Uncertain
Tissue: cerebral cortex; Cell type: neuronal cells; Level: Negative; Expression type: Staining; Reliability: Uncertain
Tissue: cervix, uterine; Cell type: glandular cells; Level: Negative; Expression type: Staining; Reliability: Uncertain
Tissue: cervix, uterine; Cell type: squamous epithelial cells; Level: Negative; Expression type: Staining; Reliability: Uncertain
Tissue: colon; Cell type: glandular cells; Level: Weak; Expression type: Staining; Reliability: Uncertain
Tissue: duodenum; Cell type: glandular cells; Level: Negative; Expression type: Staining; Reliability: Uncertain
Tissue: epididymis; Cell type: glandular cells; Level: Moderate; Expression type: Staining; Reliability: Uncertain
Tissue: esophagus; Cell type: squamous epithelial cells; Level: Negative; Expression type: Staining; Reliability: Uncertain
Tissue: fallopian tube; Cell type: glandular cells; Level: Negative; Expression type: Staining; Reliability: Uncertain
Tissue: gall bladder; Cell type: glandular cells; Level: Weak; Expression type: Staining; Reliability: Uncertain
Tissue: heart muscle; Cell type: myocytes; Level: Negative; Expression type: Staining; Reliability: Uncertain
Tissue: hippocampus; Cell type: glial cells; Level: Negative; Expression type: Staining; Reliability: Uncertain
Tissue: hippocampus; Cell type: neuronal cells; Level: Negative; Expression type: Staining; Reliability: Uncertain
Tissue: kidney; Cell type: cells in glomeruli; Level: Negative; Expression type: Staining; Reliability: Uncertain
Tissue: kidney; Cell type: cells in tubules; Level: Weak; Expression type: Staining; Reliability: Uncertain
Tissue: lateral ventricle; Cell type: glial cells; Level: Negative; Expression type: Staining; Reliability: Uncertain
Tissue: lateral ventricle; Cell type: neuronal cells; Level: Negative; Expression type: Staining; Reliability: Uncertain
Tissue: liver; Cell type: bile duct cells; Level: Negative; Expression type: Staining; Reliability: Uncertain
Tissue: liver; Cell type: hepatocytes; Level: Negative; Expression type: Staining; Reliability: Uncertain
Tissue: lung; Cell type: macrophages; Level: Moderate; Expression type: Staining; Reliability: Uncertain
Tissue: lung; Cell type: pneumocytes; Level: Negative; Expression type: Staining; Reliability: Uncertain
Tissue: lymph node; Cell type: germinal center cells; Level: Negative; Expression type: Staining; Reliability: Uncertain
Tissue: lymph node; Cell type: non-germinal center cells; Level: Weak; Expression type: Staining; Reliability: Uncertain
Tissue: nasopharynx; Cell type: respiratory epithelial cells; Level: Strong; Expression type: Staining; Reliability: Uncertain
Tissue: oral mucosa; Cell type: squamous epithelial cells; Level: Negative; Expression type: Staining; Reliability: Uncertain
Tissue: ovary; Cell type: follicle cells; Level: Negative; Expression type: Staining; Reliability: Uncertain
Tissue: ovary; Cell type: ovarian stroma cells; Level: Weak; Expression type: Staining; Reliability: Uncertain
Tissue: pancreas; Cell type: exocrine glandular cells; Level: Weak; Expression type: Staining; Reliability: Uncertain
Tissue: pancreas; Cell type: islets of Langerhans; Level: Negative; Expression type: Staining; Reliability: Uncertain
Tissue: parathyroid gland; Cell type: glandular cells; Level: Negative; Expression type: Staining; Reliability: Uncertain
Tissue: placenta; Cell type: decidual cells; Level: Negative; Expression type: Staining; Reliability: Uncertain
Tissue: placenta; Cell type: trophoblastic cells; Level: Negative; Expression type: Staining; Reliability: Uncertain
Tissue: prostate; Cell type: glandular cells; Level: Moderate; Expression type: Staining; Reliability: Uncertain
Tissue: rectum; Cell type: glandular cells; Level: Weak; Expression type: Staining; Reliability: Uncertain
Tissue: salivary gland; Cell type: glandular cells; Level: Negative; Expression type: Staining; Reliability: Uncertain
Tissue: seminal vesicle; Cell type: glandular cells; Level: Negative; Expression type: Staining; Reliability: Uncertain
Tissue: skeletal muscle; Cell type: myocytes; Level: Negative; Expression type: Staining; Reliability: Uncertain
Tissue: skin; Cell type: epidermal cells; Level: Negative; Expression type: Staining; Reliability: Uncertain
Tissue: small intestine; Cell type: glandular cells; Level: Negative; Expression type: Staining; Reliability: Uncertain
Tissue: smooth muscle; Cell type: smooth muscle cells; Level: Negative; Expression type: Staining; Reliability: Uncertain
Tissue: spleen; Cell type: cells in red pulp; Level: Negative; Expression type: Staining; Reliability: Uncertain
Tissue: spleen; Cell type: cells in white pulp; Level: Weak; Expression type: Staining; Reliability: Uncertain
Tissue: stomach, lower; Cell type: glandular cells; Level: Weak; Expression type: Staining; Reliability: Uncertain
Tissue: stomach, upper; Cell type: glandular cells; Level: Moderate; Expression type: Staining; Reliability: Uncertain
Tissue: testis; Cell type: cells in seminiferus ducts; Level: Moderate; Expression type: Staining; Reliability: Uncertain
Tissue: testis; Cell type: Leydig cells; Level: Moderate; Expression type: Staining; Reliability: Uncertain
Tissue: thyroid gland; Cell type: glandular cells; Level: Negative; Expression type: Staining; Reliability: Uncertain
Tissue: tonsil; Cell type: germinal center cells; Level: Negative; Expression type: Staining; Reliability: Uncertain
Tissue: tonsil; Cell type: non-germinal center cells; Level: Weak; Expression type: Staining; Reliability: Uncertain
Tissue: tonsil; Cell type: squamous epithelial cells; Level: Weak; Expression type: Staining; Reliability: Uncertain
Tissue: urinary bladder; Cell type: urothelial cells; Level: Strong; Expression type: Staining; Reliability: Uncertain
Tissue: uterus, post-menopause; Cell type: cells in endometrial stroma; Level: Weak; Expression type: Staining; Reliability: Uncertain
Tissue: uterus, post-menopause; Cell type: glandular cells; Level: Weak; Expression type: Staining; Reliability: Uncertain
Tissue: uterus, pre-menopause; Cell type: cells in endometrial stroma; Level: Negative; Expression type: Staining; Reliability: Uncertain
Tissue: uterus, pre-menopause; Cell type: glandular cells; Level: Moderate; Expression type: Staining; Reliability: Uncertain
Tissue: vagina; Cell type: squamous epithelial cells; Level: Negative; Expression type: Staining; Reliability: Uncertain
Tissue: vulva/anal skin; Cell type: epidermal cells; Level: Negative; Expression type: Staining; Reliability: Uncertain

Danio rerio Chromosome position LG 25