Protein S100A7

URN urn:agi-llid:6278
Total Entities 0
Connectivity 858
Name S100A7
Description S100 calcium binding protein A7
Notes The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein differs from the other S100 proteins of known structure in its lack of calcium binding ability in one EF-hand at the N-terminus. The protein is overexpressed in hyperproliferative skin diseases, exhibits antimicrobial activities against bacteria and induces immunomodulatory activities. [provided by RefSeq, Nov 2014]
Primary Cell Localization Plasma membrane

Pathway Proteins Involved in Atherosclerosis
IL17 Signaling in Psoriasis
Proteins Involved in Psoriasis
IL22 Induces Keratinocyte Proliferation in Psoriasis
Proteins with Altered Expression in Psoriasis
Dendritic Cells Function in Psoriasis
Keratinocyte Activation in Psoriatic Arthritis
Overview. Diseases of the skin (chapter 11)
2_Interleukin-17 and interleukin-22 signaling in psoriasis
Interleukin-17 and interleukin-22 signaling in psoriasis

MedScan ID 6278

LocusLink ID 6278

Alias Psoriasin
OTTHUMP00000015328
PSOR1
PSOR I
psoriasin 1
OTTHUMP00000015327
S100RVP
psoriasin I
S100 calcium binding protein A7
S100A7
s100a7c
S100 calcium binding protein A7 (psoriasin 1)
S100 calcium-binding protein
LOC310568
protein S100-A7
S100 calcium-binding protein A7 (psoriasin 1)

GO ID 0050786
0005509
0008270
0001525
0061844
0019730
0050829
0008544
0045087
0030216
0043312
0070374
0010820
0071624
0090026
0032496
0000302
0051238
0035578
0062023
0005737
0005829
0005783
0005576
0005615
0005925
0005634
0070062

KEGG ID hsa:6278

Organism Homo sapiens {Organism urn:agi-taxid:9606}
Homo sapiens

OMIM ID 600353

Hugo ID 10497

Human chromosome position 1q21.3
1q21

Swiss-Prot Accession P31151
P31151.4
Q5SY67
Q6FGE3
Q9H1E2

PIR ID A54327

GenBank ID NC_000001
NM_002963
NP_002954
AF050167
AJ012825
CAC20409
AL591704
BR000043
FAA00017
CH471121
EAW53327
AW238300
BC034687
AAH34687
BF090388
BX476368
CR542164
CAG46961
M86757
AAA60210
S81991
P31151
NC_018912
AMYH02001902
DQ891277
ABM82203
DQ894465
ABM85391

Swiss-Prot ID S10A7_HUMAN

Cell Localization Cytoplasm
Secreted

Ensembl ID ENSG00000143556
ENSP00000357712.3
ENST00000368723.4
ENSP00000357712
ENST00000368723

Unigene ID Hs.112408