Protein EGFR

URN urn:agi-llid:1956
Total Entities 0
Connectivity 20033
Name EGFR
Description epidermal growth factor receptor
Notes The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. [provided by RefSeq, Jun 2016]
Primary Cell Localization Plasma membrane
Class Receptor

Pathway Proteins Involved in Stem Cell Exhaustion in Aging
Skin Aging
Prolactin Production
Vascular Smooth Muscle Cell/Pericyte Migration and Proliferation
NTSR1 Expression Targets
DRD2 Expression Targets
DRD2 -> TRPC1 Transcription
CHRM1 -> IL2 Production
Luteinizing Hormone in Oocyte Meiotic Resumption
G0/G1 Phase Transition
Gap Junction Assembly
Axonal Transport
Transcytosis
Proteins Involved in Atherosclerosis
Scavenger Receptor OLR1 in Inflammation Related Endothelial Dysfunction
Proteins Involved in Dilated Cardiomyopathy
Proteins Involved in Hypertrophic Cardiomyopathy
Proteins Involved in Arterial Hypertension
Arterial Hypertension
Endothelial Cell Dysfunction in Arterial Hypertension
Proteins Involved in Pulmonary Hypertension
Smooth Muscle Cell Dysfunction in Pulmonary Hypertension
Myocardial Remodeling
Proteins Involved in Myocarditis
Proteins with Altered Expression in Melanoma
Melanoma
Proteins Involved in Melanoma
Proteins Involved in Psoriasis
Apoptotic Keratinocytes Clearance Recession in Systemic Lupus Erythematosus
Proteins Involved in Diabetic Nephropathy
Hepatic Stellate Cells in non-Alcoholic Fatty Liver Disease
beta-Cell Mass Regulation
Prolactinoma Overiew
Proteins Involved in Colorectal Neoplasms
Cetuximab Resistance in Colorectal Cancer
Metastatic Colorectal Cancer
EGFR Nuclear Signaling in Colorectal Cancer
OipA Signaling in Helicobacter Pylori Infection
Apoptosis through VacA in Helicobacter Pylori Infection
CagA Phosphorylation Dependent Signaling
Multiple Myeloma
Proteins Involved in Hepatocellular Carcinoma
Hepatocellular Carcinoma
Growth Factor Signaling in Hepatocellular Carcinoma
Proteins Involved in Pancreatic Cancer
Pancreatic Ductal Carcinoma
Growth Factor Signaling in Pancreatic Neoplasms
Pancreatic Neuroendocrine Tumors
Goblet-Cell Exocytosis in Asthma
Goblet-Cell Related Mucus Secretion in Asthma
Mucin Production in Goblet Airway Epithelial Cells
Axonal Transport Impairment in Hungtington Disease
Glioblastoma, Primary
Glioblastoma, Classical Subtype
Proteins Involved in Glioblastoma
Glioblastoma, Secondary
Astrocytoma
Proteins Involved in Oligodendroglioma
Proteins Involved in Astrocytoma
Glioma Invasion Signaling
Proteins Involved in Glioma
Growth Factor Signaling in Neuroblastoma
Neuroblastoma
Proteins Involved in Neuroblastoma
Proteins Involved in Breast Cancer Related to NOTCH Signaling Pathway
Proteins Involved in Breast Cancer Related to ERBB2/VEGFR/Akt Signaling Pathway
ERBB/VEGFR/Akt Signaling in Breast Cancer
ESR1/ERBB Positive Luminal Breast Cancer
Proteins with Altered Expression in Breast Cancer
Breast Cancer
NOTCH1 Signaling in Breast Cancer
Endometrial Cancer
Endometrioid Endometrial Cancer
Clear Cell Endometrial Cancer and Papillary Serous Endometrial Cancer
Proteins with Altered Expression in Endometrial Cancer
Proteins Involved in Endometriosis
Proteins Involved in High-Grade Serous Ovarian Carcinoma
Endometrioid Ovarian Carcinoma
Proteins Involved in Endometrioid Ovarian Carcinoma
Proteins Involved in Mucinous Ovarian Carcinoma
EGFR and PTAFR Signaling in Ovarian Cancer
High-Grade Serous Ovarian Carcinoma
Low-Grade Serous Ovarian Carcinoma
Proteins Involved in Low-Grade Serous Ovarian Carcinoma
Ovarian Cancer
Mucinous Ovarian Carcinoma
Proteins with Altered Expression in Ovarian Cancer
EGF/cyclinD1 Signaling in Acquired Middle Ear Cholesteatoma
Subepithelial Fibroblasts in Middle Ear Cholesteatoma
Cholesteatoma
HPV Infection and Cancer
HPV E5 Regulates EDNRA and EGFR Signaling Pathway in Keratinocytes
Androgen Receptor Coregulator ARA55 (TGFB1I1) in Prostate Cancer
Prostate Cancer
Proteins Involved in Prostate Cancer
Proteins Involved in Otitis Media
Cytokines Trigger Otitis Media
Proteins Involved in Chronic Obstructive Pulmonary Disease
Mucin Hyperproduction in Goblet and Mucous Cells
Proteins Involved in Polycystic Kidney Disease
Proteins Involved in Glomerulonephritis
Sertoli Cells Dysfunction Causes Male Infertility
AREG -> NFATC Expression Target
AREG -> CREB/CREBBP Expression Targets
AREG -> NCOR2 Expression Targets
AREG -> SMAD1 Expression Target
AREG -> CTNN Expression Targets
AREG -> HIF1A Expression Targets
AREG -> STAT Expression Targets
AREG -> AP-1 Expression Targets
AREG -> FOXO3A Expression Target
Acetylcholine Expression Targets
Dopamine/Gi Expression Targets
Aryl Hydrocarbon Receptor Genomic and non-Genomic Signaling
BMP4/BMPR2 Expression Targets
BTC -> NFATC Expression Targets
BTC -> AP-1/ATF/CREB Expression Targets
BTC -> CTNN Expression Targets
BTC -> STAT Expression Targets
GPCR Family -> Expression Targets in Adipose Tissue
Receptor Tyrosine Kinase Family -> Expression Targets in Bone
Elevated Receptors -> Expression Targets in Blood vessel
Elevated Receptors -> Expression Targets in Myocardium
Elevated Receptors -> Expression Targets in Aorta
Elevated Receptors -> Expression Targets in Blood Vessel
CXCL12 Expression Targets
CSF2 -> NF-kB Expression Targets
Tamoxifen Induced Endometrial Cancer
EGF -> CTNN Expression Targets
EGF -> HIF1A Expression Targets
EGF -> AP-1/ATF Expression Targets
EGF -> CREB/CREBBP/ELK/SRF/MYC Expression Targets
EGF -> MEF/MYOD/NFATC Expression Targets
EGF -> FOXO3A Expression Targets
EGF -> TP53 Expression Targets
EGF -> NCOR2 Expression Target
EGF -> STAT Expression Targets
EGFR -> NCOR2 Signaling
EGFR/ERBB3 -> MEF/MYOD/NFATC/MYOG Signaling
EGFR -> CTNND Signaling
EGFR/ERBB2 -> TP53 Signaling
EGFR/ERBB2 -> CTNNB Signaling
EGFR -> SMAD1 Signaling
EGFR/ERBB2 -> HIF1A Signaling
EGFR -> ZNF259 Signaling
EGFR -> AP-1/ATF2 Signaling
EGFR -> AP-1/CREB/ELK/SRF/MYC Signaling
EGFR/ERBB -> STAT Signaling
EREG -> CREB Expression Target
EREG -> FOXO3A Expression Target
EREG -> CTNNB/CTNND Expression Target
EREG -> STAT Expression Targets
EREG -> HIF1A Expression Target
EREG -> AP-1/ATF Expression Targets
Elevated Receptors -> Expression Targets in Endocrine Gands
F2 -> AP-1/CREB/ELK/SRF/SP1 Expression Targets
F2 -> STAT1/NF-kB Expression Targets
PLG -> AP-1/CREB/ELK/SRF/SP1 Expression Targets
PLG -> STAT1/NF-kB Expression Targets
FGF2 -> STAT Expression Targets
FGF7 -> AP-1/CREB/CREBBP/MYC Expression Targets
FGF2 -> AP-1/CREB/CREBBP/ELK/SRF/MYC Expression Targets
GCG Expression Targets
FSHR Expression Targets
Glutamate/Gq Expression Targets
VIP Expression Targets
Elevated Receptors -> Expression Targets in Mouth
EGFR -> Expression Targets in Colon
HBEGF -> STAT Expression Targets
HBEGF -> FOXO3A Expression Target
HBEGF -> AP-1/ATF Expression Targets
HBEGF -> TP53 Expression Targets
HBEGF -> EP300/ETS/ETV/SP1 Expression Targets
HBEGF -> HIF1A Expression Targets
HBEGF -> MEF/MYOD Expression Target
HBEGF -> CREB/MYC Expression Targets
HGF -> STAT Expression Targets
HGF -> AP-1/CREB/ELK/SRF/MYC Expression Targets
EGFR Transactivation in Cancer and Non-Cancer Cells
TAM Receptor Signaling Activation in Cancer
Receptors and Adaptor Proteins Activated in Cancer
Proteins with Altered Expression in Cancer-Associated Sustaining of Proliferative Signaling
Genes with Mutations in Cancer-Associated Sustaining of Proliferative Signaling
G0/G1 Cell Cycle Phase Transition Activation in Cancer
STAT3 and NFkB Activate Inflammation-Induced Tumorigenesis
VEGFA Dependent Angiogenesis in Cancer
Integrins in Cancer Cell Motility, Invasion and Survival
Proteins with Altered Expression in Cancer Metastases
Epithelial to Mesenchymal Transition in Cancer: Overview
BSG (CD147) in Cancer Cells Motility, Invasion and Survival
Hyaluronic Acid, CD44 and HMMR in Cancer Cell Invasion and Survival
Invadopodia Formation in Cancer Cells
Lipogenesis/Lipolysis Activation in Cancer Cells and Cancer-Associated Adipocytes
Genes with Mutations in Cancer Metabolic Reprogramming
Proteins with Altered Expression in Cancer Metabolic Reprogramming
IGF1 -> MEF/MYOD/MYOG Expression Targets
IGF1 -> STAT Expression Targets
IGF1 -> ELK/SRF/HIF1A/MYC/SREBF Expression Targets
Insulin -> STAT Expression Targets
Insulin -> CEBPA/CTNNB/FOXA/FOXO Expression Targets
Insulin -> MEF/MYOD Expression Targets
Insulin -> ELK/SRF/HIF1A/MYC/SREBF Expression Targets
Fibrinogen Expression Targets
EGFR -> Expression Targets in Skin
IL3 Expression Targets
Leptin -> STAT Expression Targets
Leptin -> ELK/SRF Expression Targets
Prostaglandin F Expression Targets
LPA Expression Targets
PAF/Gq -> AP-1/ATF1/CREB/ERK/SRF Expression Targets
Dronabinol/Anandamide Expression Targets
Morphine Expression Targets
S1P Expression Targets
EGFR-> Expression Targets in Lymphoid System and Blood
GPCRs Family -> Expression Targets in Lymphoid System and Blood
NRG1 -> MEF/MYOD Expression Targets
NRG1 -> CREB/CREBBP/ELK/SRF/MYC Expression Targets
NRG1 -> FOXO3A Expression Targets
NRG1 -> TP53 Expression Target
NRG1/Catenin Expression Targets
NRG1 -> STAT Expression Targets
NRG1 -> AP-1/ATF Expression Targets
NRG1 -> HIF1A Expression Target
NOTCH 1/3 -> Expression Targets in Nerve Tissue
Elevated Receptors -> Expression Targets in Nerve Tissue
Elevated Receptors -> Expression Targets in Parathyroid Gland
NGF -> SMAD3/NF-kB Expression Targets
NTF3 Expression Targets
DLL4 Expression Targets
ADAM17 Expression Targets
DLL1 Expression Targets
NOTCH Expression Targets
PDGF -> AP-1/CREB/CREBBP/MYC Expression Targets
PDGF -> STAT Expression Targets
AVP/Gs -> CREB/ELK/SRF/AP-1/EGR Expression Targets
GNRH1 Expression Targets
NTS Expression Targets
EDN1 Expression Targets
AGT -> CREB Expression Targets
AVP/Gs -> MEF/MYOD/NFATC/MYOG Expression Targets
AVP/Gq -> STAT Expression Targets
IFNA1/Gq Expression Targets
AGT -> ELK/SRF Expression Targets
TAC1 Expression Targets
AVP/Gs -> STAT Expression Targets
AVP/Gq -> MEF/MYOD/NFATC/MYOG Expression Targets
AGT -> STAT Expression Targets
AVP/Gq -> CREB/ELK/SRF/AP-1/EGR Expression Targets
KITLG -> STAT Expression Targets
KITLG -> AP-1/CREB/CREBBP/MYC Expression Targets
PAF Expression Targets
Elevated Receptors -> Expression Targets in Breast
Elevated Receptors -> Expression Targets in Endometrium
Elevated Receptors -> Expression Targets in Placenta
Elevated Receptors -> Expression Targets in Respiratory System
FOXO1 Signaling
Estrogens/ESR1 non-Genomic Signaling
EGFR Signaling
HRAS Signaling
ERK/MAPK Canonical Signaling
TGFA -> STAT Expression Targets
TGFA -> FOXO3A Expression Targets
TGFA -> CTNNB/CTNND Expression Targets
TGFA -> TP53 Expression Targets
TGFA -> HIF1A Expression Targets
TGFA -> MEF/MYOD/NFATC Expression Targets
TGFA/AP-1/ATF Expression Targets
TGFA -> CREB/CREBBP/ELK-SRF/MYC Expression Targets
TGFB1-TGFBR2 Expression Targets
TGFB1-TGFBR1/AP-1 Expression Targets
TGFB1-ACVRL1 Expression Targets
TNF -> NF-kB Expression Targets
TNF -> AP-1 Expression Targets
TNF -> TP53/ATF Expression Targets
EDA Expression Targets
IL1B -> PGE2 Expression Targets
IL1B Expression Targets
IL1A Expression Targets
ROS in Angiotensin Mediated Cardiovascular Remodeling and Hypertrophy
WNT1 Expression Targets
WNT7B Expression Targets
WNT5A Expression Targets
ace2
prarg negative regulators, ps-positive
pprarg neg, uknown targets, ps-positive
prarg neg,ukn expres targets, ps-positive
PPARG negative regulators
PPARG negative targets
pparg expr target_regulators
Neighbors of disease exacerbation
Neighbors of tumor progression
Neighbors of cancer progression
Neighbors of inflammatory status
Neighbors of overall survival
Neighbors of disease severity
Neighbors of tumor size
Neighbors of lesion size
Neighbors of mortality
Neighbors of survival rate
Neighbors of infarct size
Neighbors of survival time
Neighbors of functional recovery
Neighbors of insulin sensitivity
Neighbors of bacterial load
Neighbors of cancer survival
Neighbors of graft survival
Neighbors of therapeutic efficacy
Neighbors of clinical stage
Neighbors of lethality
Neighbors of tumor regression
Neighbors of recurrence-free survival
Neighbors of disease-free survival
Neighbors of tumor response
Neighbors of macrophage count
Neighbors of long-term survival
Neighbors of treatment outcome
Neighbors of bone mass
Neighbors of body weight
Neighbors of body weight gain
Neighbors of cardiovascular risk
Neighbors of microvessel density
Neighbors of tumor recurrence
Neighbors of tumor promotion
Neighbors of neutrophil count
Neighbors of glucose tolerance
Neighbors of morbidity
Neighbors of fibrosis progression
Neighbors of mortality rate
Neighbors of adverse outcome
Neighbors of radioresistance
Neighbors of cell density
Neighbors of cancer-specific survival
Neighbors of progression-free survival
Neighbors of apoptosis rate
Neighbors of shear stress
Neighbors of viral load
Neighbors of blood pressure
Neighbors of leukocyte count
Neighbors of tumor grade
Neighbors of vascular reactivity
Neighbors of vascular leakage
Neighbors of vascular density
Neighbors of muscle mass
Neighbors of cancer risk
Neighbors of cancer incidence
Neighbors of tumor aggressiveness
Neighbors of systolic blood pressure
Neighbors of tumor resistance
Neighbors of blood glucose
Neighbors of ejection fraction
Neighbors of median survival
Neighbors of renal hypertrophy
Neighbors of fasting plasma glucose
Neighbors of osteoclast number
Neighbors of T-cell count
Neighbors of antimetastatic activity
Neighbors of energy expenditure
Neighbors of glucose level
Neighbors of vascular tone
Neighbors of radiosensitivity
Neighbors of left ventricular ejection fraction
Neighbors of breast cancer risk
Neighbors of proliferation index
Neighbors of fertility
Neighbors of recurrence rate
Neighbors of pathological response
Neighbors of skin thickness
Neighbors of metabolic response
Neighbors of insulin level
Neighbors of comorbidity
Neighbors of disease exacerbation
Neighbors of tumor progression
Neighbors of cancer progression
Neighbors of inflammatory status
Neighbors of overall survival
Neighbors of disease severity
Neighbors of tumor size
Neighbors of lesion size
Neighbors of mortality
Neighbors of survival rate
Neighbors of infarct size
Neighbors of survival time
Neighbors of functional recovery
Neighbors of insulin sensitivity
Neighbors of bacterial load
Neighbors of cancer survival
Neighbors of graft survival
Neighbors of therapeutic efficacy
Neighbors of clinical stage
Neighbors of lethality
Neighbors of tumor regression
Neighbors of recurrence-free survival
Neighbors of disease-free survival
Neighbors of tumor response
Neighbors of macrophage count
Neighbors of long-term survival
Neighbors of treatment outcome
Neighbors of bone mass
Neighbors of body weight
Neighbors of body weight gain
Neighbors of cardiovascular risk
Neighbors of microvessel density
Neighbors of tumor recurrence
Neighbors of tumor promotion
Neighbors of neutrophil count
Neighbors of glucose tolerance
Neighbors of morbidity
Neighbors of fibrosis progression
Neighbors of mortality rate
Neighbors of adverse outcome
Neighbors of radioresistance
Neighbors of cell density
Neighbors of cancer-specific survival
Neighbors of progression-free survival
Neighbors of apoptosis rate
Neighbors of shear stress
Neighbors of viral load
Neighbors of blood pressure
Neighbors of leukocyte count
Neighbors of tumor grade
Neighbors of vascular reactivity
Neighbors of vascular leakage
Neighbors of vascular density
Neighbors of muscle mass
Neighbors of cancer risk
Neighbors of cancer incidence
Neighbors of tumor aggressiveness
Neighbors of systolic blood pressure
Neighbors of tumor resistance
Neighbors of blood glucose
Neighbors of ejection fraction
Neighbors of median survival
Neighbors of renal hypertrophy
Neighbors of fasting plasma glucose
Neighbors of osteoclast number
Neighbors of T-cell count
Neighbors of antimetastatic activity
Neighbors of energy expenditure
Neighbors of glucose level
Neighbors of vascular tone
Neighbors of radiosensitivity
Neighbors of left ventricular ejection fraction
Neighbors of breast cancer risk
Neighbors of proliferation index
Neighbors of fertility
Neighbors of recurrence rate
Neighbors of pathological response
Neighbors of skin thickness
Neighbors of metabolic response
Neighbors of insulin level
Neighbors of comorbidity
Neighbors of cell development
Neighbors of immune response
Neighbors of cell population
Neighbors of T-cell development
Neighbors of inflammatory response
Neighbors of wound healing
Neighbors of angiogenesis
Neighbors of innate immune response
Neighbors of cell function
Neighbors of macrophage activation
Neighbors of cell formation
Neighbors of adaptive immune response
Neighbors of osteoclast development
Neighbors of epithelial to mesenchymal transition
Neighbors of immunity
Neighbors of cell proliferative response
Neighbors of chemotaxis
Neighbors of dendritic cell differentiation
Neighbors of cell survival
Neighbors of osteoclast differentiation
Neighbors of cell phenotype
Neighbors of T-cell proliferation
Neighbors of tissue remodeling
Neighbors of cell adhesion
Neighbors of T-cell activation
Neighbors of endothelial cell proliferation
Neighbors of fibrogenesis
Neighbors of tumor growth
Neighbors of dendritic cell development
Neighbors of tissue repair
Neighbors of cell count
Neighbors of cell infiltration
Neighbors of cell interaction
Neighbors of SMC proliferation
Neighbors of lumen formation
Neighbors of endothelial cell migration
Neighbors of adipogenesis
Neighbors of lipid storage
Neighbors of cell damage
Neighbors of pregnancy
Neighbors of aging
Neighbors of cell motility
Neighbors of bone resorption
Neighbors of fibroblast proliferation
Neighbors of adipocyte differentiation
Neighbors of macrophage migration
Neighbors of microglial activation
Neighbors of neutrophil recruitment
Neighbors of regeneration
Neighbors of cell migration
Neighbors of cancer growth
Neighbors of stem cell proliferation
Neighbors of smooth muscle cell migration
Neighbors of hepatic regeneration
Neighbors of transendothelial migration
Neighbors of phagocytosis
Neighbors of immune system activation
Neighbors of leukocyte migration
Neighbors of leukocyte recruitment
Neighbors of osteoclast formation
Neighbors of monocyte recruitment
Neighbors of cell invasion
Neighbors of heart function
Neighbors of hemopoiesis
Neighbors of ossification
Neighbors of T-cell function
Neighbors of immune system function
Neighbors of lung development
Neighbors of autophagy
Neighbors of monocyte adhesion
Neighbors of transcription activation
Neighbors of senescence
Neighbors of T-cell response
Neighbors of tumor immunity
Neighbors of hepatocyte proliferation
Neighbors of cell transdifferentiation
Neighbors of neuroprotection
Neighbors of stem cell differentiation
Neighbors of endothelial cell function
Neighbors of neuronal death
Neighbors of cell growth
Neighbors of ROS generation
Neighbors of epithelial cell proliferation
Neighbors of first trimester pregnancy
Neighbors of cancer cell growth
Neighbors of sensitization
Neighbors of hemato-encephalic barrier
Neighbors of macrophage function
Neighbors of cellular immune response
Neighbors of cellular senescence
Neighbors of colony formation
Neighbors of cell differentiation
Neighbors of keratinocyte proliferation
Neighbors of stem cell migration
Neighbors of life span
Neighbors of cell homeostasis
Neighbors of psoriasis
Neighbors of inflammatory disease
Neighbors of rheumatoid arthritis
Neighbors of atherosclerosis
Neighbors of fibrosis
Neighbors of colitis
Neighbors of arthritis
Neighbors of inflammatory bowel disease
Neighbors of injury
Neighbors of atherogenesis
Neighbors of vascular remodeling
Neighbors of metastasis
Neighbors of carcinogenesis
Neighbors of multiple sclerosis
Neighbors of chronic inflammation
Neighbors of inflammation
Neighbors of tumor microenvironment
Neighbors of pathological angiogenesis
Neighbors of obesity
Neighbors of vascular disease
Neighbors of diabetes mellitus
Neighbors of asthma
Neighbors of pneumonia
Neighbors of hyperplasia
Neighbors of osteoarthritis
Neighbors of liver fibrosis
Neighbors of chronic obstructive pulmonary disease
Neighbors of myocardial infarction
Neighbors of leukocyte infiltration
Neighbors of reperfusion injury
Neighbors of airway inflammation
Neighbors of insulin resistance
Neighbors of infection
Neighbors of vascular injury
Neighbors of renal injury
Neighbors of preeclampsia
Neighbors of macrophage infiltration
Neighbors of liver injury
Neighbors of neuroinflammation
Neighbors of death
Neighbors of type 1 diabetes
Neighbors of dermatitis
Neighbors of neutrophil infiltration
Neighbors of heart disease
Neighbors of diabetic nephropathy
Neighbors of lung injury
Neighbors of systemic sclerosis
Neighbors of hepatocellular carcinoma
Neighbors of acute lung injury
Neighbors of gastric cancer
Neighbors of colorectal cancer
Neighbors of cardiac remodeling
Neighbors of breast cancer
Neighbors of ischemia
Neighbors of systemic lupus erythematosus
Neighbors of melanoma
Neighbors of collagen-induced arthritis
Neighbors of cartilage degeneration
Neighbors of interstitial fibrosis
Neighbors of neoplasm invasion
Neighbors of kidney disease
Neighbors of heart failure
Neighbors of lung disease
Neighbors of pulmonary fibrosis
Neighbors of cardiovascular disease
Neighbors of stroke
Neighbors of cancer
Neighbors of type 2 diabetes
Neighbors of neoplasm
Neighbors of endometriosis
Neighbors of neointima
Neighbors of atrophy
Neighbors of diet-induced obesity
Neighbors of respiratory hypersensitivity
Neighbors of myocardial fibrosis
Neighbors of synovitis
Neighbors of rupture
Neighbors of endothelial cell dysfunction
Neighbors of prostate cancer
Neighbors of hypertrophy
Neighbors of osteolysis
Neighbors of ovarian cancer
Neighbors of pancreatic cancer
Neighbors of hypertension
Neighbors of intimal hyperplasia
Neighbors of proteinuria
Neighbors of epithelial cell
Neighbors of keratinocyte
Neighbors of monocyte
Neighbors of macrophage
Neighbors of fibroblast
Neighbors of airway epithelial cell
Neighbors of stromal cell
Neighbors of osteoblast
Neighbors of pneumocyte
Neighbors of intestine epithelium cell
Neighbors of mononuclear cell
Neighbors of hepatocyte
Neighbors of neutrophil
Neighbors of astrocyte
Neighbors of stem cell
Neighbors of granulosa cell
Neighbors of T-cell
Neighbors of neuroglia
Neighbors of lung
Neighbors of liver
Neighbors of kidney
Neighbors of skin
Neighbors of intestine
Neighbors of lymph node
Neighbors of colon
Neighbors of airway
Neighbors of blood vessel
Neighbors of heart
Neighbors of gastrointestinal tract
Neighbors of bone
Neighbors of placenta
Neighbors of esophagus
Neighbors of brain
Neighbors of ovary
Neighbors of breast
Neighbors of stomach
Neighbors of pancreas
Neighbors of prostate
Neighbors of central nervous system
Neighbors of colorectal region
Neighbors of alveolus
Neighbors of vein
Neighbors of eye
Neighbors of lymph node of mesentery
Neighbors of mammary gland
Neighbors of cerebral cortex
Neighbors of bladder
Neighbors of nervous system
Neighbors of blastocyst
Neighbors of endocrine system
Neighbors of lymphatic vessels
Neighbors of pleura
Neighbors of hair follicle
Neighbors of NF-kB family
Neighbors of oxidized LDL
Neighbors of JNK
Neighbors of PPAR
Neighbors of Jun/Fos
Neighbors of PKC
Neighbors of PI3K
Neighbors of mitogen-activated protein kinase
Neighbors of IFNAR ligand
Neighbors of transforming growth factor
Neighbors of cytokine
Neighbors of interferon
Neighbors of PDGF
Neighbors of Ras GTPase
Neighbors of ERK1/2
Neighbors of growth factor
Neighbors of PKA
Neighbors of ovalbumin
Neighbors of LDL
Neighbors of NF-AT family
Neighbors of beta adrenoceptor
Neighbors of chorionic gonadotropin
Neighbors of IKBK
Neighbors of protein tyrosine kinase
Neighbors of NAD(P)H oxidase
Neighbors of IgG
Neighbors of SMAD subfamily
Neighbors of AMPK
Neighbors of estrogen receptor
Neighbors of histone deacetylase
Neighbors of PDGF-BB
Neighbors of IL1R
Neighbors of HIF-1
Neighbors of GPCR
Neighbors of Notch
Neighbors of heat shock protein 90
Neighbors of lectin
Neighbors of fibrinogen
Neighbors of endothelin
Neighbors of NOS
Neighbors of proteasome endopeptidase complex
Neighbors of class nuclear receptor with C4 zinc fingers
Neighbors of non-coding RNA
Neighbors of histone H3
Neighbors of alpha2 adrenoceptor
Neighbors of vitronectin receptor (integrin)
Neighbors of retinoid-X receptor subfamily
Neighbors of WNT
Neighbors of gonadotropins
Neighbors of immunoglobulin
Neighbors of phospholipase
Neighbors of ITG
Neighbors of FSH
Neighbors of RA receptor
Neighbors of neuropeptides
Neighbors of adrenoceptor
Neighbors of caspase
Neighbors of phosphoinositide phospholipase C
Neighbors of TNF-alpha receptor
Model of PPARG signaling in psoriasis
PPARG negative regulators and targets
Model of PPARG related pathways in psoriasis (short version)
3_Mesangial cell dysfunction in glomerulonephritis
2_Pathogens stimulate mucins expression in the middle ear
2_The intense proliferation and contractile activity of smooth muscle cells in pulmonary hypertension
3_1_Mucus accumulation in asthma
4_Mucin hyperproduction in goblet and mucous cells in COPD
3_Human papilloma virus E4 and E5 proteins in viral reproduction
drug-target pairs binding
drug-target pairs direct regulation
New Combined Pathway
Model of PPARG signaling in psoriais (tested)
opcs
DIPG cell biomarkers
mapk1 protein modificators

Group Genes with Mutations Associated with Colorectal Cancer
Genes with Mutations Associated with Primary Glioblastoma
Genes with Mutations Associated with Glioma
Chemokines, Growth Factors and Receptors Involved in Cancer Cells Chemotaxis

MedScan ID 1956

LocusLink ID 1956
13649
24329

Alias RP23-295E4.1
erbB receptor
avian erythroblastic leukemia viral (v-erb-b) oncogene homolog
v-erbB oncogene homolog
v-erb-b
epidermal growth factor receptor 1
HER1
EGF-Rs
transforming growth factor-alpha receptor
TGF-alpha receptor
epidermal growth factor receptor vIII
epidermal growth factor receptor variant III
Egfr
EGF-R
truncated epidermal growth factor receptor
EGFR-related peptide
cell proliferation-inducing protein 61
Errb1
epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)
epidermal growth factor receptors
avian erythroblastic leukemia viral (v-erbB) oncogene homolog
Epidermal growth factor receptor formerly avian erythroblastic leukemia viral (v-erbB) oncogene homolog
9030024J15
Errp
GNB:6478868
EGF receptors
OTTMUSP00000005385
epidermal growth factor receptor
erythroblastic leukemia viral (v-erb-b) oncogene homolog
erb-b2 receptor tyrosine kinase 1
mENA
receptor tyrosine-protein kinase erbB-1
EGFR_HUMAN
EGFRvIII
PIG61
AI552599
OTTHUMP00000209210
cell growth inhibiting protein 40
OTTMUSP00000005386
RIKEN cDNA 9030024J15 gene
EGF receptor
ERBB I
erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian
v-erb-bs
EGF/TGF-alpha receptor
TGF-alpha receptors
EGFR1
NISBD2
LOC360274
ERB1
Epidermal growth factor receptor formerly avian erythroblastic leukemia viral (v-erbB) oncogene homolog (Erbb1)
proto-oncogene c-ErbB-1
EGFR_MOUSE
receptor for epidermal growth factor
EGFRs
ERBB
wa II
ERBB1
transforming growth factor-alpha receptors
erbB receptors
EGF holoreceptor
EGFR vIII
9030024J15Rik
waved 2
epidermal growth factor receptor tyrosine kinase domain
Wa5
wa2
wa-2
ErbB-1
epidermal growth factor receptor, formerly avian erythroblastic leukemia viral (v-erbB) oncogene homolog (Erbb1)
erythroblastic leukaemia viral (v-erb-b) oncogene homolog, avian
epidermal growth factor receptor (erythroblastic leukaemia viral (v-erb-b) oncogene homolog, avian)
avian erythroblastic leukaemia viral (v-erb-b) oncogene homolog
avian erythroblastic leukaemia viral (v-erbB) oncogene homolog
Epidermal growth factor receptor formerly avian erythroblastic leukaemia viral (v-erbB) oncogene homolog
erythroblastic leukaemia viral (v-erb-b) oncogene homolog
epidermal growth factor receptor (avian erythroblastic leukemia viral (v-er
epidermal growth factor receptor (avian erythroblastic leukaemia viral (v-er

EC Number 2.7.10.1

GO ID 0005524
0004709
0051015
0045296
0005516
0003682
0003690
0019899
0048408
0005006
0005178
0030235
0046982
0019901
0019903
0004713
0004714
0004888
0031625
0001618
0038128
0000165
0000186
0043006
0007202
0048143
0030154
0008283
0007166
0098609
0071230
0071276
0071549
0071364
0071392
0071260
0034614
0021795
0007623
0048546
0016101
0001892
0007173
0061029
0001942
0042743
0007611
0097421
0030324
0010960
0061024
0007494
0060571
1901185
0045746
0043066
1905208
0042059
0045930
0042177
0048812
0001503
0042698
0038083
0018108
0045739
0045740
0070374
1900087
0043406
1901224
0097755
0045780
0090263
0030307
0030335
0008284
0045737
0050679
0048146
0050729
0010750
0033138
0042327
1903800
1902722
0051897
1900020
1903078
0001934
0048661
0032930
0051968
0045944
0045893
0045907
0046777
0051205
0070372
0046328
2000145
0050999
0050730
0014066
0006357
0070141
0051592
0033590
0033594
0006970
0007435
0007165
0043586
0006412
0007169
0046718
0042060
0000139
0070435
0016324
0009925
0016323
0009986
0030665
0005737
0031901
0030139
0005789
0005768
0010008
0005615
0005925
0005887
0016020
0045121
0097489
0031965
0005634
0048471
0005886
0032991
0043235
0045202
0016301
0000166
0004672
0005102
0016740
0000902
0071363
0008544
0035556
0007275
0016310
0006468
0006898
0042127
0005794
0005783
0016021
0035690
0001889
0032355
0033993
0014070
0006979
0005088
0046934
0004716
0046854
0048015
0043547
0035413
0031659
0045429
0006950
0016337
0030122
0001948
0004871
0045909
0005622
0023014
0038095
0019694
0007411
0008543
0045087
0048011
0016772
0005976

KEGG ID hsa:1956
mmu:13649
rno:24329

Organism Homo sapiens {Organism urn:agi-taxid:9606}
Mus musculus {Organism urn:agi-taxid:10090}
Rattus norvegicus {Organism urn:agi-taxid:10116}
Homo sapiens
Mus musculus
Rattus norvegicus

Mouse chromosome position 11 9.41 cM

OMIM ID 131550
616069
211980

Rat chromosome position 14q22

Hugo ID 3236
HGNC:3236

Human chromosome position 7p11.2
7p12

Swiss-Prot Accession Q504U8
E7BSV0
F2YGG7
E9PFD7
B7Z2I3
P00533
P00533.2
Q9WVF5
Q01279
Q3TQS6
Q9EP98
Q01279.1
Q9QX70
O00688
O00732
P06268
Q14225
Q68GS5
Q92795
Q9BZS2
Q9GZX1
Q9H2C9
Q9H3C9
Q9UMD7
Q9UMD8
Q9UMG5

PIR ID A00641
A53183

GenBank ID NC_000007
NM_005228
NP_005219
NM_001346941
NP_001333870
NM_001346898
NP_001333827
NM_001346897
NP_001333826
NM_201284
NP_958441
NM_201282
NP_958439
NM_001346899
NP_001333828
NM_201283
NP_958440
NM_001346900
NP_001333829
NG_007726
AB221348
BAE15958
AB360371
BAF79636
AB360855
BAF80003
AB360856
BAF80004
AB685813
BAL40868
AB686642
BAL41217
AC006977
AC073324
AAS07524
AF040717
AF288738
AAG35786
AAG35787
AAG35788
AAG35789
AAG35790
AH006650
AAC50796
AAC50797
AAC50798
AAC50799
AAC50800
AAC50801
AH010139
AAG43243
AAG43244
AAG43245
AY588246
AAS83109
CH236957
CH471201
EAW50962
EAW50963
EAW50964
EAW50965
CS238505
CAJ55813
CS542488
CAM91181
GM619915
CAV33298
HC464560
CBK51921
HC464562
CBK51922
HC464564
CBK51923
HC464566
CBK51924
HF548011
CCO13722
J03206
JA807020
CCO75437
JA807083
CCO75439
JA913745
CCV20014
JC478129
CEF34368
JQ739160
AFK93471
JQ739161
AFK93472
JQ739162
AFK93473
JQ739163
AFK93474
JQ739164
AFK93475
JQ739165
AFK93476
JQ739166
AFK93477
JQ739167
AFK93478
KF458469
KJ685773
AIE16170
KJ685774
AIE16171
KT584716
KX162725
ART34939
KX162726
ART34940
KX162727
ART34941
KX162728
ART34942
KX162729
ART34943
KX162730
ART34944
KX162731
ART34945
KX819315
ART92273
M11234
AAA52370
M23390
M38425
AAA63171
U48723
AAC50803
AAC50804
X06370
CAA29668
X17054
CAA34902
AB209442
BAD92679
AF125253
AAG43240
AF277897
AAK01080
AI217671
AK127817
AK225422
AK290352
BAF83041
AK294750
BAH11869
AL598260
AU137334
AW163038
AW295229
AW450657
AY550966
AAT52212
AY698023
AAT97978
AY698024
AAT97979
BC070081
BC094761
AAH94761
BC118665
AAI18666
BC128419
AAI28420
CB160831
DA371223
DC347326
DQ088980
AAZ66620
EF210210
ABQ66237
EF210211
ABQ66238
GU228573
GU228584
GU255993
ADL28125
HM437234
ADN43066
HM437235
HQ730875
HQ912715
ADZ75461
HQ999997
ADY76965
K03193
AAA52371
U48722
AAC50802
U51732
U95089
AAB53063
X00588
CAA25240
X00663
CAA25282
P00533
NC_000077
NM_207655
NP_997538
NM_007912
NP_031938
AF125256
AAG43241
AF456454
AAL56615
AH009944
AAG28045
AAG28046
AAG28047
AL645532
BX255277
CH466574
EDL40666
EDL40667
HM570131
HM570132
HM570133
HM570134
HM570135
HM570136
HM570137
HM570138
HM570139
HM570140
HM570141
HM570142
HM570143
HM570144
HM570145
HM570146
HM570147
HM570148
HM570149
HM570150
HM570151
HM570152
HM570153
HM570154
HM570155
HM570156
AF124513
AAD44149
AF275367
AAG24386
AF277898
AAK01081
AK004883
BAB23641
AK004911
BAB23662
AK004944
BAB23688
AK014017
AK033431
AK049452
AK087861
AK134262
AK163338
BAE37306
BC023729
AAH23729
BC030681
BQ553815
BY725722
L06864
AAA53029
U03425
AAA17899
X59698
CAA42219
X78987
CAA55587
Z12608
CAA78249
Q01279
NC_005113
NM_031507
NP_113695
XM_008770416
XP_008768638
XM_008770418
XP_008768640
XM_017599073
XP_017454562
AC_000082
AABR07016425
AABR07016426
AABR07016427
AABR07072433
AAHX01081375
AAHX01081376
AAHX01081377
AAHX01081378
AAHX01081379
AAHX01081380
AAHX01081381
AB025197
BAA76391
AC098180
AF142153
AAF27540
CH473996
EDL97895
EDL97896
AB079120
BAF82007
FQ209947
FQ210224
FQ211093
HM801041
ADT91284
HM801042
ADT91285
M37394
AAF14008
U52529
AAC53049
NC_018918
AF125538
AF125539
AMYH02015730
AMYH02015731
AC_000033
AAHY01090988
AAHY01090989
AAHY01090990
S50852
S50853
S50854
S50855
XM_008770417
XP_008768639
AC_000139
ABBA01011847
ABBA01011848
ABBA01011849
ABBA01011850
U48724
U48725
U48726
U48727
U48728
U48729
XM_006514491
XP_006514554
AF275364
AF275365
AF275366
XM_005271748
XP_005271805
XM_005271746
XP_005271803
XM_005271747
XP_005271804
AC_000068
AACC02000089
AABR06080997
AABR06080998
AABR06080999
AABR06081000
AABR06081001

Swiss-Prot ID EGFR_HUMAN
EGFR_MOUSE

Cell Localization Cell membrane
Endoplasmic reticulum membrane
Golgi apparatus membrane
Nucleus membrane
Endosome
Endosome membrane
Nucleus
Secreted
Plasma membrane

Ensembl ID ENSG00000146648
ENSP00000415559.1
ENST00000455089.5
ENSP00000395243.3
ENST00000454757.6
ENSP00000275493.2
ENST00000275493.7
ENSP00000342376.3
ENST00000342916.7
ENSP00000413843.2
ENST00000420316.6
ENSP00000345973.2
ENST00000344576.6
ENSMUSG00000020122
ENSMUSP00000099948.3
ENSMUST00000102884.9
ENSMUSP00000020329.6
ENSMUST00000020329.12
ENSRNOG00000004332
ENSRNOP00000006087.2
ENSRNOT00000006087.2
ENSP00000275493
ENST00000275493
ENSP00000342376
ENST00000342916
ENSP00000413843
ENST00000420316
ENSP00000345973
ENST00000344576
ENSMUSP00000099948
ENSMUST00000102884
ENSMUSP00000020329
ENSMUST00000020329
ENSRNOP00000006087
ENSRNOT00000006087
ENSP00000395243
ENST00000454757
ENSP00000410031
ENST00000442591

MGI ID MGI:95294
95294

RGD ID 2543

Unigene ID Hs.488293
Hs.605083
Mm.8534
Mm.420648
Mm.439882
Rn.37227

Homologene ID 74545

Shape Stick-vertex