Protein PLAAT4

URN urn:agi-llid:5920
Total Entities 0
Connectivity 442
Name PLAAT4
Description retinoic acid receptor responder (tazarotene induced) 3
Notes Retinoids exert biologic effects such as potent growth inhibitory and cell differentiation activities and are used in the treatment of hyperproliferative dermatological diseases. These effects are mediated by specific nuclear receptor proteins that are members of the steroid and thyroid hormone receptor superfamily of transcriptional regulators. RARRES1, RARRES2, and RARRES3 are genes whose expression is upregulated by the synthetic retinoid tazarotene. RARRES3 is thought act as a tumor suppressor or growth regulator. [provided by RefSeq, Jul 2008]

Pathway TLR4 Signaling in Leukocytes
Dendritic Cell Dysfunction in Crohn's disease
Model of PPARG signaling in psoriasis
1_Defects in response to pathogens in the gut promotes inflammation in Crohn's disease

MedScan ID 5920

LocusLink ID 5920

Alias RIG1
TIG3
PLAAT4
tazarotene-induced gene 3
PLA1/2-3
RAR-responsive protein TIG3
RARRES3
MGC8906
phospholipase A and acyltransferase 4
HRAS-like suppressor 4
PLAAT-4
retinoid-inducible gene 1 protein
HRSL4
retinoic acid receptor responder protein 3
retinoic acid receptor responder (tazarotene induced) 3
HRASLS4
phospholipase A/acyltransferase-4
retinoic acid receptor responder (tazarotene induced) III
retinoic acid receptor responder 3
retinoic acid-inducible gene 1
tazarotene-induced gene 3 protein

EC Number 3.1.1.32
3.1.1.4
2.3.1.-
3.1.1.-

GO ID 0052740
0016410
0052739
0008970
0004623
0102567
0102568
0070292
0016042
0008285
0036152
0006644
0045618
0150074
0005829
0016021
0016020

KEGG ID hsa:5920

Organism Homo sapiens {Organism urn:agi-taxid:9606}
Homo sapiens

OMIM ID 605092

Hugo ID 9869

Human chromosome position 11q12.3
11q23

Swiss-Prot Accession Q9UL19
Q9UL19.1
B2R599
B4DDW2
E7ENZ7
O95200

GenBank ID NC_000011
NM_004585
NP_004576
AP001591
CH471076
EAW74156
KF455398
AB030815
BAB08109
AB453252
BAH22446
AF060228
AAC84000
AF092922
AAF02294
AK293357
BAG56873
AK312110
BAG35046
BC009678
AAH09678
DA973023
LC420314
BBG06131
R55646
Q9UL19
NC_018922
AMYH02024911
DQ891444
ABM82370
DQ894622
ABM85548

Swiss-Prot ID PLAT4_HUMAN
HRSL4_HUMAN

Cell Localization Membrane

Ensembl ID ENSG00000133321
ENSP00000255688.3
ENST00000255688.8
ENSP00000255688
ENST00000255688

Unigene ID Hs.17466