Pathway
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Androgen Deficiency in Male Obesity
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SIRT2 Signaling in Aging
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SIRT7 Signaling in Aging
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SIRT1 Signaling in Aging
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MTOR/TP53 Regulates Cell Metabolism
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Insulin Influence on Protein Synthesis
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Insulin Signaling
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Androgens in Adipocyte Activation
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LH and FSH Signaling and Steroidogenesis
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V(D)J Recombination Activation
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Adipokines Production by Adipocyte
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Lipolysis Regulation in Adipocyte
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SCF/SKP2 Complex
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Proteins Involved in Hypertrophic Cardiomyopathy
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Proteins Involved in Acne Vulgaris
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Hyperseborrhea in Acne Vulgaris
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Androgen Induced Sebocyte Hyperfunction
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Androgens in Sebocyte Maturation
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Proteins Involved in Diabetes Mellitus Type 2
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Donohue Syndrome Progression (Hypothesis)
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Proteins Involved in Insulin Resistance
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Adiponectin Synthesis Declines in Insulin Resistance
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Proteins Involved in non-Alcoholic Fatty Liver Disease
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Gluconeogenesis Impairment in non-Alcoholic Fatty Liver Disease
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PNPLA3 in non-Alcoholic Fatty Liver Disease
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FOXO1 and SREBP-1C Role in beta-Cell Suppression (Rodent Model)
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Myocyte Dysfunction in Hypoparathyroidism
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Adipocyte Hypertrophy and Hyperplasia
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Adipokines Production by Adipocyte Impaired in Obesity
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Peutz-Jeghers Syndrome
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B-Cell Acute Lymphoblastic Leukemia
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B-Cell Chronic Lymphocytic Leukemia
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T-Cell Acute Lymphoblastic Leukemia
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Proteins Involved in Hepatocellular Carcinoma
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Hepatocellular Carcinoma
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Growth Factor Signaling in Hepatocellular Carcinoma
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Pancreatic Ductal Carcinoma
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Growth Factor Signaling in Pancreatic Neoplasms
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Ovulation Block
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SHBG and IGFBP1 Synthesis Decline in Polycystic Ovary Syndrome
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Polycystic Ovary Syndrome
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FSH Action in Polycystic Ovary Syndrome
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TNF Receptor Associated Periodic Syndrome
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Cowden Syndrome
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ER Stress in Huntington Disease
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Ca2+ Overload in Muscular Dystrophies
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Muscular Dystrophies
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Dystrophin Glycoprotein Complex Signaling in Muscular Dystrophies
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IGF1 Role in Muscle Hypertrophy
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Myostatin-IGF1 Crosstalk in Skeletal Muscles in Muscular Dystrophies
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Proteins Involved in Medulloblastoma
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ERBB/VEGFR/Akt Signaling in Breast Cancer
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IGF1R/AKT Signaling in Breast Cancer
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ESR1/ERBB Positive Luminal Breast Cancer
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Breast Cancer
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ESR1 Signaling in Breast Cancer
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Endometrial Cancer
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Endometrioid Endometrial Cancer
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Clear Cell Endometrial Cancer and Papillary Serous Endometrial Cancer
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Proteins with Altered Expression in Endometriosis
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Progesterone Resistance in Endometriosis
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Endometrioid Ovarian Carcinoma
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Clear Cell Ovarian Carcinoma
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High-Grade Serous Ovarian Carcinoma
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Low-Grade Serous Ovarian Carcinoma
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Ovarian Cancer
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Mucinous Ovarian Carcinoma
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Proteins Involved in Primary Ovarian Insufficiency
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LH and FSH Signaling Impairment in Primary Ovarian Insufficiency
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Androgen Receptor/Akt Signaling
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Alveolar Epithelial Cell Autophagy in COPD
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FSHR Expression Targets
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PI3K/AKT/MTOR Signaling Activation in Cancer
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PI3K/AKT/MTOR Signaling Activation by Blocking of Tumor Suppressors
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ANGPT/TEK Maintains Endothelial Cell Quiescence in Cancer
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ANGPT/TEK Stimulates Endothelial Cell Migration in Cancer
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Skeletal Muscle Wasting in Cancer Cachexia
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IGF1 -> CEBPA/FOXO1A Expression Targets
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IGF2 -> CEBPA/FOXO1A Expression Targets
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Insulin -> STAT Expression Targets
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Insulin -> CEBPA/CTNNB/FOXA/FOXO Expression Targets
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ICAM2 -> CTNNB/FOXO/STAT3 Signaling
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InsulinR -> CTNNB/FOXA/FOXO Signaling
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IGF1R -> CEBPA/FOXO1A Signaling
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IL7R -> FOXO/NF-kB Signaling
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IL7 Expression Targets
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Leptin -> STAT Expression Targets
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NGF -> FOXO/MYCN/ELK-SRF Expression Targets
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BDNF Expression Targets
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NTF3 Expression Targets
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AngiopoietinR -> FOXO Signaling
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NTRK -> FOXO/MYCN Signaling
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Androgen Receptor non-Genomic Signaling
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FOXO1 Signaling
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AMPK Signaling
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prarg negative regulators, ps-positive
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PPARG negative regulators
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pparg expr target_regulators
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Neighbors of disease exacerbation
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Neighbors of tumor progression
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Neighbors of cancer progression
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Neighbors of overall survival
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Neighbors of disease severity
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Neighbors of lesion size
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Neighbors of mortality
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Neighbors of survival rate
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Neighbors of infarct size
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Neighbors of survival time
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Neighbors of insulin sensitivity
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Neighbors of graft survival
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Neighbors of lethality
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Neighbors of recurrence-free survival
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Neighbors of long-term survival
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Neighbors of bone mass
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Neighbors of body weight
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Neighbors of body weight gain
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Neighbors of glucose tolerance
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Neighbors of fat mass
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Neighbors of exhaustion
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Neighbors of bone mineral density
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Neighbors of shear stress
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Neighbors of viral load
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Neighbors of blood pressure
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Neighbors of muscle mass
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Neighbors of tumor aggressiveness
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Neighbors of systolic blood pressure
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Neighbors of blood glucose
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Neighbors of renal hypertrophy
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Neighbors of fasting plasma glucose
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Neighbors of osteoclast number
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Neighbors of T-cell count
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Neighbors of energy expenditure
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Neighbors of glucose level
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Neighbors of left ventricular ejection fraction
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Neighbors of proliferation index
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Neighbors of fertility
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Neighbors of metabolic response
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Neighbors of insulin level
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Neighbors of carotid intima-media thickness
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Neighbors of bone volume
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Neighbors of fractional shortening
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Neighbors of disease exacerbation
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Neighbors of tumor progression
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Neighbors of cancer progression
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Neighbors of overall survival
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Neighbors of disease severity
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Neighbors of lesion size
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Neighbors of mortality
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Neighbors of survival rate
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Neighbors of infarct size
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Neighbors of survival time
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Neighbors of insulin sensitivity
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Neighbors of graft survival
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Neighbors of lethality
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Neighbors of recurrence-free survival
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Neighbors of long-term survival
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Neighbors of bone mass
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Neighbors of body weight
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Neighbors of body weight gain
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Neighbors of glucose tolerance
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Neighbors of fat mass
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Neighbors of exhaustion
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Neighbors of bone mineral density
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Neighbors of shear stress
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Neighbors of viral load
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Neighbors of blood pressure
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Neighbors of muscle mass
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Neighbors of tumor aggressiveness
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Neighbors of systolic blood pressure
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Neighbors of blood glucose
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Neighbors of renal hypertrophy
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Neighbors of fasting plasma glucose
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Neighbors of osteoclast number
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Neighbors of T-cell count
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Neighbors of energy expenditure
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Neighbors of glucose level
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Neighbors of left ventricular ejection fraction
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Neighbors of proliferation index
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Neighbors of fertility
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Neighbors of metabolic response
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Neighbors of insulin level
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Neighbors of carotid intima-media thickness
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Neighbors of bone volume
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Neighbors of fractional shortening
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Neighbors of cell development
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Neighbors of immune response
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Neighbors of cell population
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Neighbors of T-cell development
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Neighbors of inflammatory response
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Neighbors of wound healing
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Neighbors of angiogenesis
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Neighbors of innate immune response
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Neighbors of cell function
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Neighbors of macrophage activation
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Neighbors of cell formation
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Neighbors of adaptive immune response
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Neighbors of osteoclast development
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Neighbors of epithelial to mesenchymal transition
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Neighbors of immunity
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Neighbors of cell proliferative response
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Neighbors of chemotaxis
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Neighbors of cell survival
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Neighbors of osteoclast differentiation
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Neighbors of cell phenotype
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Neighbors of T-cell proliferation
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Neighbors of cell adhesion
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Neighbors of T-cell activation
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Neighbors of endothelial cell proliferation
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Neighbors of fibrogenesis
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Neighbors of tumor growth
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Neighbors of tissue repair
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Neighbors of cell count
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Neighbors of cell interaction
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Neighbors of SMC proliferation
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Neighbors of lumen formation
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Neighbors of endothelial cell migration
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Neighbors of adipogenesis
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Neighbors of lipid storage
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Neighbors of cell damage
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Neighbors of pregnancy
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Neighbors of aging
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Neighbors of cell motility
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Neighbors of fibroblast proliferation
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Neighbors of adipocyte differentiation
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Neighbors of microglial activation
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Neighbors of regeneration
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Neighbors of cell migration
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Neighbors of cancer growth
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Neighbors of stem cell proliferation
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Neighbors of hepatic regeneration
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Neighbors of phagocytosis
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Neighbors of immune system activation
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Neighbors of leukocyte migration
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Neighbors of osteoclast formation
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Neighbors of cell invasion
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Neighbors of heart function
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Neighbors of bone remodeling
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Neighbors of ossification
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Neighbors of T-cell function
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Neighbors of immune system function
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Neighbors of autophagy
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Neighbors of monocyte adhesion
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Neighbors of transcription activation
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Neighbors of senescence
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Neighbors of T-cell response
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Neighbors of hepatocyte proliferation
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Neighbors of cell transdifferentiation
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Neighbors of neuroprotection
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Neighbors of stem cell differentiation
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Neighbors of endothelial cell function
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Neighbors of neuronal death
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Neighbors of cell growth
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Neighbors of ROS generation
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Neighbors of cancer cell growth
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Neighbors of sensitization
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Neighbors of hemato-encephalic barrier
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Neighbors of macrophage function
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Neighbors of cellular immune response
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Neighbors of cellular senescence
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Neighbors of colony formation
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Neighbors of cell differentiation
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Neighbors of keratinocyte proliferation
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Neighbors of life span
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Neighbors of cell homeostasis
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Neighbors of psoriasis
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Neighbors of inflammatory disease
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Neighbors of rheumatoid arthritis
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Neighbors of atherosclerosis
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Neighbors of fibrosis
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Neighbors of inflammatory bowel disease
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Neighbors of injury
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Neighbors of vascular remodeling
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Neighbors of metastasis
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Neighbors of carcinogenesis
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Neighbors of inflammation
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Neighbors of tumor microenvironment
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Neighbors of obesity
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Neighbors of vascular disease
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Neighbors of diabetes mellitus
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Neighbors of asthma
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Neighbors of pneumonia
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Neighbors of hyperplasia
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Neighbors of liver fibrosis
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Neighbors of chronic obstructive pulmonary disease
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Neighbors of myocardial infarction
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Neighbors of reperfusion injury
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Neighbors of hepatitis
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Neighbors of insulin resistance
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Neighbors of infection
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Neighbors of vascular injury
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Neighbors of renal injury
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Neighbors of liver injury
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Neighbors of neuroinflammation
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Neighbors of sepsis
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Neighbors of death
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Neighbors of type 1 diabetes
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Neighbors of encephalomyelitis
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Neighbors of autoimmune disease
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Neighbors of ischemic stroke
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Neighbors of neutrophil infiltration
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Neighbors of heart disease
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Neighbors of diabetic nephropathy
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Neighbors of lung injury
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Neighbors of hepatocellular carcinoma
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Neighbors of autoimmunity
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Neighbors of gastric cancer
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Neighbors of colorectal cancer
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Neighbors of cardiac remodeling
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Neighbors of breast cancer
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Neighbors of ischemia
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Neighbors of neoplasm invasion
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Neighbors of kidney disease
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Neighbors of heart failure
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Neighbors of cardiovascular disease
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Neighbors of stroke
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Neighbors of cancer
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Neighbors of cerebral ischemia
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Neighbors of type 2 diabetes
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Neighbors of neoplasm
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Neighbors of atrophy
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Neighbors of diet-induced obesity
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Neighbors of myocardial fibrosis
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Neighbors of endothelial cell dysfunction
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Neighbors of liver disease
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Neighbors of prostate cancer
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Neighbors of hypertrophy
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Neighbors of osteolysis
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Neighbors of ovarian cancer
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Neighbors of proteinuria
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Neighbors of monocyte
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Neighbors of macrophage
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Neighbors of hepatocyte
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Neighbors of endothelial cell
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Neighbors of peritoneal macrophage
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Neighbors of stem cell
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Neighbors of insulin-secreting cell
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Neighbors of T-cell
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Neighbors of liver
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Neighbors of skin
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Neighbors of intestine
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Neighbors of blood vessel
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Neighbors of heart
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Neighbors of microvessel
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Neighbors of uterus
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Neighbors of esophagus
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Neighbors of central nervous system
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Neighbors of lymphatic system
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Neighbors of NF-kB family
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Neighbors of oxidized LDL
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Neighbors of JNK
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Neighbors of PPAR
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Neighbors of Jun/Fos
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Neighbors of PI3K
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Neighbors of STAT family
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Neighbors of PDGF
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Neighbors of ERK1/2
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Neighbors of growth factor
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Neighbors of chorionic gonadotropin
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Neighbors of IKBK
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Neighbors of AMPK
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Neighbors of T-cell receptor
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Neighbors of histone deacetylase
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Neighbors of HIF-1
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Neighbors of IL12
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Neighbors of TSH
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Neighbors of proteasome endopeptidase complex
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Neighbors of non-coding RNA
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Neighbors of STAT5
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Neighbors of gonadotropins
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Neighbors of FSH
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Neighbors of histone
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Neighbors of histone acetyltransferase
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Neighbors of deacetylase
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Model of PPARG signaling in psoriasis
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PPARG negative regulators and targets
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Model of PPARG related pathways in psoriasis (short version)
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H2A-K119 and H3-K27
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New Pathway
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3_Increased proliferation of sebocytes in acne vulgaris
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2_Progesterone resistance stimulates endometriotic cell survival
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2_Impaired steroidogenesis in PCOS
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2_Cigarette smoke and inflammation cause alveolar epithelial cell death in COPD
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1_1_Insulin synthesis and secretion: insulin processing and storage
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3_3_Beta-cell proliferation and compensation: recovery
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4_1_Insulin resistance: insulin signaling
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4_3_Insulin resistance: FFA-related insulin resistance
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