Protein ZFYVE9

URN urn:agi-llid:9372
Total Entities 0
Connectivity 263
Name ZFYVE9
Description zinc finger FYVE-type containing 9
Notes This gene encodes a double zinc finger motif-containing protein that participates in the transforming growth factor-beta (TGFB) signalling pathway. The encoded protein interacts directly with SMAD2 and SMAD3, and recruits SMAD2 to the TGFB receptor. There are multiple pseudogenes for this gene on chromosomes 2, 15, and X. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2013]

Pathway TGF-beta Signaling
1_Differentiation of psoriatic T cells
Differentiation of psoriatic T cells

MedScan ID 9372

LocusLink ID 9372
230597
313477

Alias PPP1R173
OTTMUSP00000032178
MAD (mothers against decapentaplegic, Drosophila) homolog interacting prote
zinc finger, FYVE domain containing 9
LOC381539
MAD, mothers against decapentaplegic homolog interacting prote
Receptor activation anchor
LOC277733
ZFYVE9
MADH interacting protein
OTTHUMP00000009741
Receptor activating anchor
RP23-406B13.8
SARA
MADH-interacting protein
SMADIP
E030027L17
MADH-interactive protein
protein phosphatase 1, regulatory subunit 173
AK087111
OTTMUSP00000032179
zinc finger FYVE-type containing 9
Smad anchor for receptor activation
hSARA
Mothers against decapentaplegic homolog interacting protein
LOC230597
MAD, mothers against decapentaplegic homolog interacting protein, receptor activation anchor
OTTHUMP00000009739
MAD homolog interacting protein
zinc finger, FYVE domain containing IX
OTTHUMP00000009740
MADHIP
OTTMUSP00000008607
Mothers against decapentaplegic homolog interactive protein
NSP
novel serine protease
zinc finger FYVE domain-containing protein 9

GO ID 0005545
0046872
0019904
0006897
0016197
0007179
0005829
0005769
0031901
0043231
0032991
0046332
0017015
0005737
0008236
0007183
0007184
0006508

KEGG ID hsa:9372

Organism Homo sapiens {Organism urn:agi-taxid:9606}
Mus musculus {Organism urn:agi-taxid:10090}
Rattus norvegicus {Organism urn:agi-taxid:10116}
Homo sapiens
Mus musculus
Rattus norvegicus

Mouse chromosome position 4

OMIM ID 603755

Rat chromosome position 5q34
5q35

Hugo ID 6775

Human chromosome position 1p32.3

Swiss-Prot Accession O95405
O95405.2
A2A8R0
A0S860
A8Y5G5
Q5T0F6
Q5T0F7
Q9UNE1
Q9Y5R7

GenBank ID NC_000001
XM_017002845
XP_016858334
NM_007324
NP_015563
NM_004799
NP_004790
XM_011542437
XP_011540739
AC105754
AL139156
AL513218
CH471059
EAX06790
EAX06791
EAX06792
HF583785
CCQ43282
AB209125
BAD92362
AF104304
AAC99462
AF130419
AAD31694
AF130420
AAD31695
BC032680
AAH32680
DR005493
O95405
NC_000070
XM_006502988
XP_006503051
XM_006502986
XP_006503049
XM_017320143
XP_017175632
XM_006502989
XP_006503052
XM_006502987
XP_006503050
NM_183300
NP_899123
NM_001347163
AL607070
AL626783
AL671909
CH466527
EDL30733
AK081320
AK087111
BAC39805
AK135219
BAE22464
BC038255
BC046341
AAH46341
BC058416
AAH58416
BC079578
BC094578
DQ303413
ABC18000
NC_005104
NM_001107952
NP_001101422
AC_000073
AABR07049553
AABR07049554
AAHX01039043
CH474008
EDL90393
EDL90394
NC_018912
AMYH02001011
AMYH02001012
AMYH02001013
AMYH02001014
AMYH02001015
AMYH02001016
AMYH02001017
AMYH02001018
EU176568
ABW03369
AC_000026
AAHY01038999
AAHY01039000
AAHY01039001
AAHY01039002
AAHY01039003
AAHY01039004
BC156514
AAI56515
BC172690
AAI72690

Swiss-Prot ID ZFYV9_HUMAN

Cell Localization Cytoplasm
Early endosome membrane

Ensembl ID ENSG00000157077
ENSP00000287727.3
ENST00000287727.7
ENSP00000349737.2
ENST00000357206.6
ENSMUSG00000034557
ENSMUSP00000039852.7
ENSMUST00000042185.7
ENSMUSP00000102269.1
ENSMUST00000106658.7
ENSMUSP00000102268.1
ENSMUST00000106657.7
ENSRNOG00000027183
ENSRNOP00000036295.6
ENSRNOT00000037523.6
ENSP00000287727
ENST00000287727
ENSP00000349737
ENST00000357206
ENSP00000360647
ENST00000371591
ENSMUSP00000039852
ENSMUST00000042185
ENSMUSP00000102269
ENSMUST00000106658
ENSMUSP00000102268
ENSMUST00000106657
ENSRNOP00000036295
ENSRNOT00000037523

MGI ID MGI:2652838

RGD ID 1310856

Unigene ID Hs.532345
Mm.196776
Rn.23612

Homologene ID 3527