URN | urn:agi-llid:2625 |
---|---|
Total Entities | 0 |
Connectivity | 3021 |
Name | GATA3 |
Description | GATA binding protein 3 |
Notes | This gene encodes a protein which belongs to the GATA family of transcription factors. The protein contains two GATA-type zinc fingers and is an important regulator of T-cell development and plays an important role in endothelial cell biology. Defects in this gene are the cause of hypoparathyroidism with sensorineural deafness and renal dysplasia. [provided by RefSeq, Nov 2009] |
Primary Cell Localization | Nucleus |
Class | Transcription factor |
Pathway | T-Cell Maturation (Hypothesis) |
---|---|
Th2-Cell Differentiation | |
Acute Phase in Atopic Dermatitis | |
Atopic Dermatitis | |
T-Cells Differentiation Block in Psoriasis | |
Proteins with Altered Expression in Psoriasis | |
Th2-Cell Function in Systemic Lupus Erythematosus | |
Vitiligo | |
T-Cell Cytotoxic Response against Melanocytes in Vitiligo | |
Immune System Activation in Hyperthyroidism | |
Proteins Involved in Hypoparathyroidism | |
Hypoparathyroidism, Primary | |
CD4+T-Cell Response in Celiac Disease | |
B-Cell Activation in Crohn's Disease | |
Th2-Cell Function in Ulcerative Colitis | |
Hodgkin Lymphoma | |
Hodgkin and Reed-Sternberg Cells Reprogramming | |
T-Cell Acute Lymphoblastic Leukemia | |
Proteins Involved in Pancreatic Cancer | |
Th2-Cell Response in Asthma | |
Th2-Cells Function in Systemic Scleroderma | |
Proteins with Altered Expression in Systemic Scleroderma | |
CD4+ T-Cell Function Decline in HIV | |
Gluten Impact on Neuronal System (Hypothesis) | |
PHOX2B Effects in Neuroblastoma | |
Neuroblastoma | |
Proteins Involved in Breast Cancer Related to ESR1 Signaling Pathway | |
Proteins Involved in Endometriosis | |
Proteins Involved in Spontaneous Abortion | |
Proteins Involved in Hearing Loss | |
IL15 Expression Targets | |
CD40 -> Expression Targets in Thymus | |
NOTCH -> Expression Targets in Thymus | |
NOTCH Receptors -> Receptors Expression Targets in Lung | |
TCR -> NF-kB Expression Targets | |
TCR -> NFAT Expression Targets | |
PPAR Psoriasis | |
Model of PPARG signaling in psoriasis | |
PPARG negative regulators and targets | |
Model of PPARG related pathways in psoriasis (short version) | |
2_Acute phase initiation in atopic dermatitis | |
1_Differentiation of psoriatic T cells | |
1_Th2 cell response in asthma | |
2_Intestine epithelial cells drive immunological responses in ulcerative colitis | |
4_1_Polymorphisms associated with inflammatory bowel diseases | |
Differentiation of psoriatic T cells |
Group | Genes with Mutations Associated with Hypoparathyroidism |
---|---|
Genes with Mutations Associated with Breast Cancer |
MedScan ID | 2625 |
---|
LocusLink ID | 2625 |
---|---|
14462 | |
85471 |
Alias | OTTHUMP00000019071 |
---|---|
RP23-276D17.1 | |
OTTHUMP00000019070 | |
transcription factor GATA3 | |
MGC5445 | |
Hypoparathyroidism, sensorineural deafness, renal dysplasia gene | |
GATA binding protein-3 | |
GATA-binding protein 3 | |
GATA binding protein 3 | |
GATA 3 transcription factor | |
GATA-binding protein-3 | |
GATA3 | |
OTTMUSP00000011932 | |
MGC5199 | |
GATA-binding factor 3 | |
GATA binding protein III | |
Trans-acting T-cell specific transcription factor GATA-3 | |
MGC2346 | |
Trans-acting T-cell specific transcription factor GATA III | |
HDR | |
HDRS | |
trans-acting T-cell-specific transcription factor GATA-3 | |
jal | |
Gata-3 |
GO ID | 0003677 |
---|---|
0001228 | |
0003700 | |
0000981 | |
0001227 | |
0070888 | |
0071837 | |
0000978 | |
0001158 | |
0005134 | |
0000987 | |
0003713 | |
0008134 | |
0044212 | |
0000976 | |
0008270 | |
0050852 | |
0045064 | |
0031929 | |
0048646 | |
0009653 | |
0003180 | |
0007411 | |
0007596 | |
0061290 | |
0003215 | |
0001709 | |
0048469 | |
0071773 | |
0035457 | |
0071353 | |
0071356 | |
0006338 | |
0090102 | |
0019221 | |
0006952 | |
0048589 | |
0043583 | |
0035162 | |
0048568 | |
0030218 | |
0006959 | |
0002520 | |
0001701 | |
0045087 | |
0042472 | |
0072643 | |
0072602 | |
0001822 | |
0002088 | |
0072676 | |
0008584 | |
0060374 | |
0060231 | |
0001823 | |
1901536 | |
0045786 | |
2000146 | |
0008285 | |
2000607 | |
2000352 | |
0045599 | |
2000703 | |
2000734 | |
0050728 | |
0032689 | |
0032703 | |
0033600 | |
0000122 | |
0045892 | |
0072179 | |
0072178 | |
0001764 | |
0042421 | |
0071599 | |
0060017 | |
0035898 | |
0060037 | |
0014065 | |
0045582 | |
2000553 | |
0010595 | |
0071442 | |
2000617 | |
2000667 | |
0032753 | |
2000664 | |
0051897 | |
0009967 | |
2000611 | |
0045944 | |
2000679 | |
0045893 | |
0072107 | |
0009791 | |
0002572 | |
0016579 | |
0043370 | |
2000683 | |
0042035 | |
0030856 | |
2000114 | |
1902036 | |
0061085 | |
0051569 | |
0072182 | |
0043523 | |
0010975 | |
0043627 | |
0045471 | |
0010332 | |
0009615 | |
0007165 | |
0048485 | |
0045061 | |
0048538 | |
0006366 | |
0001806 | |
0035799 | |
0072197 | |
0060676 | |
0060065 | |
0003281 | |
0000790 | |
0005654 | |
0005634 | |
0000977 | |
0046872 | |
0043565 | |
0003712 | |
0030217 | |
0033077 | |
0001775 | |
0000902 | |
0071345 | |
0048872 | |
0002376 | |
0010629 | |
0007399 | |
0030182 | |
0045597 | |
0001819 | |
0010628 | |
0032736 | |
0032754 | |
0006357 | |
0006355 | |
0042493 | |
0007507 | |
0072001 | |
0009887 | |
0009888 | |
0045165 | |
0006351 | |
0001077 | |
0001076 | |
0048565 | |
0001078 | |
0001046 | |
0048468 | |
0000979 | |
0001085 | |
0003682 | |
0001071 | |
0005730 | |
0005667 | |
0005623 | |
0005622 | |
0010552 | |
0016563 | |
0043193 |
KEGG ID | hsa:2625 |
---|---|
mmu:14462 | |
rno:85471 |
Organism | Homo sapiens {Organism urn:agi-taxid:9606} |
---|---|
Mus musculus {Organism urn:agi-taxid:10090} | |
Rattus norvegicus {Organism urn:agi-taxid:10116} | |
Mus musculus | |
Homo sapiens | |
Rattus norvegicus |
Mouse chromosome position | 2 6.69 cM |
---|---|
2 7.0 cM |
OMIM ID | 131320 |
---|---|
146255 |
Rat chromosome position | 17q12.3 |
---|
Hugo ID | 4172 |
---|---|
HGNC:4172 |
Human chromosome position | 10p14 |
---|---|
10p15 |
Swiss-Prot Accession | P23771 |
---|---|
P23771.1 | |
P23772 | |
Q3U0R5 | |
P23772.1 | |
Q99NH5 | |
Q5VWG7 | |
Q5VWG8 | |
Q96J16 | |
Q3TZD6 | |
Q3TZS0 | |
Q3U223 |
PIR ID | A39794 |
---|---|
B39794 |
Swiss-Prot ID | GATA3_HUMAN |
---|---|
GATA3_MOUSE | |
Q3U0R5_MOUSE | |
Q99NH5_RAT | |
Q5VWG7_HUMAN | |
Q5VWG8_HUMAN |
Cell Localization | Nucleus |
---|
Ensembl ID | ENSG00000107485 |
---|---|
ENSP00000368632.3 | |
ENST00000379328.9 | |
ENSP00000341619.3 | |
ENST00000346208.4 | |
ENSMUSG00000015619 | |
ENSMUSP00000100041.3 | |
ENSMUST00000102976.3 | |
ENSRNOG00000019336 | |
ENSRNOP00000026187.3 | |
ENSRNOT00000026187.5 | |
ENST00000379328.8 | |
ENSP00000368632 | |
ENST00000379328 | |
ENSP00000341619 | |
ENST00000346208 | |
ENSMUSP00000100041 | |
ENSMUST00000102976 | |
ENSRNOP00000026187 | |
ENSRNOT00000026187 |
MGI ID | MGI:95663 |
---|---|
95663 |
RGD ID | 621250 |
---|
Unigene ID | Hs.524134 |
---|---|
Mm.313866 | |
Rn.229174 | |
Rn.92350 |
Homologene ID | 1550 |
---|
Shape | O-vertex |
---|
IPI ID | IPI00012901 |
---|---|
IPI00216199 | |
IPI00135883 | |
IPI00198958 | |
IPI00756271 |