Protein SMURF2

URN urn:agi-llid:64750
Total Entities 0
Connectivity 653
Name SMURF2
Description SMAD specific E3 ubiquitin protein ligase 2
Primary Cell Localization Cytoplasm

Pathway Osteoarthritis
TGF-beta Signaling in Skin Aging
Proteins Involved in Osteoarthritis
TGFB2 Signaling Impairement in Osteoarthritis
Proteins with Altered Expression in Osteoarthritis
Bone Loss in Osteoporosis
Breast Cancer
Ovarian Cancer
BMP7/ACVR2 Expression Targets
TGFB Signaling activation by Blocking of Tumor Suppressors
INHBA/ACVR2/ACVR1 Expression Targets
TGFBR/BMPR -> SMAD2/3 Signaling
ActivinR -> SMAD2/3 Signaling
TGFBR1/AP-1 Signaling
MSTN/ACVR2/ACVR1 Expression Targets
TGF-beta Signaling
TGFB2-TGFBR1 Expression Targets
TGFB3-TGFBR1 Expression Targets
TGFB1-TGFBR1 Expression Targets
TGFB1-TGFBR1/AP-1 Expression Targets
1_Differentiation of psoriatic T cells
3_TGFB signaling provokes endochondral ossification with osteophyte formation
Differentiation of psoriatic T cells

MedScan ID 64750

LocusLink ID 64750
66313
303614

Alias SMURF2
MGC138150
HECT-type E3 ubiquitin transferase SMURF2
DKFZp686F0270
2810411E22
smad specific e3 ubiquitin protein ligase 2
hSMURF2
smad specific e3 ubiquitin protein ligase II
E3 ubiquitin ligase SMURF2
2810411E22Rik
SMAD ubiquitination regulatory factor 2
RP23-170A23.3
AI558114
AI649275
RGD1310067
OTTMUSP00000003747
E3 ubiquitin-protein ligase SMURF2
SMAD-specific E3 ubiquitin-protein ligase 2

EC Number 2.3.2.26
6.3.2.-

GO ID 0046332
0005160
0061630
0004842
0030509
0060071
0030514
0000122
0045892
0030512
0090263
0045732
1901165
0043161
0016579
0000209
0016567
0017015
0030579
0006511
0005737
0005829
0045121
0016607
0005654
0005634
0005886
0000151
0016740
0016020
0016874
0042787
0008766
0043773
0043774
0070739
0070735
0070737
0070736
0018169
0070740
0070738
0007179
0010467
0006367
0006351

KEGG ID hsa:64750
mmu:66313

Organism Homo sapiens {Organism urn:agi-taxid:9606}
Mus musculus {Organism urn:agi-taxid:10090}
Rattus norvegicus {Organism urn:agi-taxid:10116}
Homo sapiens
Mus musculus
Rattus norvegicus

Mouse chromosome position 11

OMIM ID 605532

Rat chromosome position 10q32.1

Hugo ID 16809
HGNC:16809

Human chromosome position 17q23.3-q24.1
17q22-q23

Swiss-Prot Accession Q96DE7
Q9HAU4
Q9HAU4.1
A2A5Z6
Q9CSE3
A2A5Z6.1
Q52LL1
Q9H260
A2A5Z7
Q5IRE6

GenBank ID NC_000017
NM_022739
NP_073576
XM_005257585
XP_005257642
AC009994
AC132812
CH471109
EAW94193
EAW94194
EAW94195
HF584194
CCQ43691
KF456306
AF301463
AAG25641
AF310676
AAG45422
AK002019
AY014180
AAG50421
BC009527
AAH09527
BC034789
BC051283
BC093876
AAH93876
BC111945
AAI11946
BP363931
CB267500
CN310238
CN370887
CR936721
Q9HAU4
NC_000077
XM_006533936
XP_006533999
XR_001780039
NM_025481
NP_079757
XM_017314705
XP_017170194
NM_001362894
AL593847
CH466558
EDL34316
AK012060
AK013082
BAB28637
AK020616
AK036718
AK161516
BAE36438
AY685230
AAV87906
BC023703
BC051489
AAH51489
BC065796
AAH65796
BC099525
BC138786
AAI38787
BC138788
AAI38789
BE986450
BU058366
BU614468
A2A5Z6
NC_005109
NM_001107061
NP_001100531
XM_017597342
XP_017452831
AC_000078
AABR07030590
AABR07030591
AABR07030592
AABR07030593
AAHX01066287
AAHX01066288
AAHX01066289
AAHX01066290
CH473948
EDM06417
XM_011525128
XP_011523430
NC_018928
AMYH02033792
AMYH02033793
XM_006533938
XP_006534001
XM_011249176
XP_011247478
AC_000033
AAHY01096058
AAHY01096059
XM_008768365
XP_008766587
AC_000149
ABBA01035289
ABBA01035290
ABBA01035291
ABBA01035292
ABBA01035293
ABBA01035294
XM_006533935
XP_006533998
XM_006533937
XP_006534000

Swiss-Prot ID SMUF2_HUMAN
SMUF2_MOUSE

Cell Localization Nucleus
Cytoplasm
Cell membrane
Membrane raft

Ensembl ID ENSG00000108854
ENSP00000262435.9
ENST00000262435.14
ENSMUSG00000018363
ENSMUSP00000090177.2
ENSMUST00000092517.8
ENSMUSP00000099356.3
ENSMUST00000103067.9
ENSRNOG00000014623
ENSRNOP00000019781.4
ENSRNOT00000019781.6
ENSP00000262435
ENST00000262435
ENSMUSP00000090177
ENSMUST00000092517
ENSMUSP00000099356
ENSMUST00000103067
ENSRNOP00000019781
ENSRNOT00000019781

MGI ID MGI:1913563

RGD ID 1310067

Unigene ID Hs.515011
Mm.340955
Rn.92843

Homologene ID 41490