Protein CXCL9

URN urn:agi-llid:4283
Total Entities 0
Connectivity 2028
Name CXCL9
Description chemokine (C-X-C motif) ligand 9
Notes This antimicrobial gene encodes a protein thought to be involved in T cell trafficking. The encoded protein binds to C-X-C motif chemokine 3 and is a chemoattractant for lymphocytes but not for neutrophils. [provided by RefSeq, Sep 2014]
Primary Cell Localization Extracellular
Class Ligand

Pathway CXC Chemokine Receptor Signaling
Macrophage M1 Lineage
Nociception Expression Targets Signaling
CCR1 Expression Targets
Proteins Involved in Atherosclerosis
Proteins Involved in Psoriasis
Toll-like Receptors in beta-Cell
Hashimoto's Thyroiditis
B-Cell Chronic Lymphocytic Leukemia
IL6/IL12 Signaling Activates Immune System in Multiple Sclerosis
Proteins Involved in Glomerulonephritis
CD8 -> STAT Expression Targets
EGFR -> Expression Targets in Skin
IFNA1/IFNR Expression Targets
IFNG/IFNR Expression Targets
GPCRs Family -> Expression Targets in Lymphoid System and Blood
Interleukin Receptors -> Expression Targets in Lymphoid System and Blood
Chemokine Receptor Family -> Expression Targets in Lymphoid System
PRL/PRLR Expression Targets
PRL/GHR -> STAT Expression Targets
PRL/GHR -> NF/kB/ELK/SRF/MYC Expression Targets
TNF -> NF-kB Expression Targets
CD40LG -> NF-kB/ELK/SRF -> CREB/NFATC Expression Targets
TNF -> STAT Expression Targets
TLR4 -> NF-kB/IRF Expression Targets
pprarg neg, uknown targets, ps-positive
prarg neg,ukn expres targets, ps-positive
PPARG negative targets
pparg expr target_regulators
Neighbors of disease exacerbation
Neighbors of tumor progression
Neighbors of cancer progression
Neighbors of overall survival
Neighbors of disease severity
Neighbors of tumor size
Neighbors of mortality
Neighbors of survival time
Neighbors of graft survival
Neighbors of lethality
Neighbors of tumor regression
Neighbors of tumor response
Neighbors of long-term survival
Neighbors of treatment outcome
Neighbors of fibrosis progression
Neighbors of cell density
Neighbors of viral load
Neighbors of T-cell count
Neighbors of disease exacerbation
Neighbors of tumor progression
Neighbors of cancer progression
Neighbors of overall survival
Neighbors of disease severity
Neighbors of tumor size
Neighbors of mortality
Neighbors of survival time
Neighbors of graft survival
Neighbors of lethality
Neighbors of tumor regression
Neighbors of tumor response
Neighbors of long-term survival
Neighbors of treatment outcome
Neighbors of fibrosis progression
Neighbors of cell density
Neighbors of viral load
Neighbors of T-cell count
Neighbors of cell development
Neighbors of immune response
Neighbors of cell population
Neighbors of T-cell development
Neighbors of inflammatory response
Neighbors of wound healing
Neighbors of angiogenesis
Neighbors of innate immune response
Neighbors of cell function
Neighbors of cell formation
Neighbors of adaptive immune response
Neighbors of epithelial to mesenchymal transition
Neighbors of immunity
Neighbors of chemotaxis
Neighbors of dendritic cell differentiation
Neighbors of cell survival
Neighbors of T-cell proliferation
Neighbors of tissue remodeling
Neighbors of cell adhesion
Neighbors of T-cell activation
Neighbors of endothelial cell proliferation
Neighbors of fibrogenesis
Neighbors of tumor growth
Neighbors of dendritic cell development
Neighbors of tissue repair
Neighbors of cell count
Neighbors of cell infiltration
Neighbors of cell interaction
Neighbors of endothelial cell migration
Neighbors of lipid storage
Neighbors of pregnancy
Neighbors of cell motility
Neighbors of bone resorption
Neighbors of monocyte migration
Neighbors of fibroblast proliferation
Neighbors of regeneration
Neighbors of cell migration
Neighbors of cancer growth
Neighbors of transendothelial migration
Neighbors of phagocytosis
Neighbors of immune system activation
Neighbors of leukocyte migration
Neighbors of leukocyte recruitment
Neighbors of monocyte recruitment
Neighbors of cell invasion
Neighbors of ossification
Neighbors of T-cell function
Neighbors of immune system function
Neighbors of T-cell response
Neighbors of tumor immunity
Neighbors of cell growth
Neighbors of ROS generation
Neighbors of first trimester pregnancy
Neighbors of sensitization
Neighbors of hemato-encephalic barrier
Neighbors of cellular immune response
Neighbors of colony formation
Neighbors of cell differentiation
Neighbors of stem cell migration
Neighbors of psoriasis
Neighbors of inflammatory disease
Neighbors of rheumatoid arthritis
Neighbors of atherosclerosis
Neighbors of fibrosis
Neighbors of colitis
Neighbors of arthritis
Neighbors of inflammatory bowel disease
Neighbors of injury
Neighbors of vascular remodeling
Neighbors of metastasis
Neighbors of carcinogenesis
Neighbors of multiple sclerosis
Neighbors of chronic inflammation
Neighbors of inflammation
Neighbors of tumor microenvironment
Neighbors of pathological angiogenesis
Neighbors of diabetes mellitus
Neighbors of asthma
Neighbors of pneumonia
Neighbors of liver fibrosis
Neighbors of myocardial infarction
Neighbors of leukocyte infiltration
Neighbors of airway inflammation
Neighbors of hepatitis
Neighbors of infection
Neighbors of vascular injury
Neighbors of macrophage infiltration
Neighbors of liver injury
Neighbors of neuroinflammation
Neighbors of death
Neighbors of autoimmune disease
Neighbors of dermatitis
Neighbors of heart disease
Neighbors of diabetic nephropathy
Neighbors of lung injury
Neighbors of immunopathology
Neighbors of hepatocellular carcinoma
Neighbors of colorectal cancer
Neighbors of cardiac remodeling
Neighbors of breast cancer
Neighbors of systemic lupus erythematosus
Neighbors of melanoma
Neighbors of neoplasm invasion
Neighbors of kidney disease
Neighbors of heart failure
Neighbors of stroke
Neighbors of cancer
Neighbors of neoplasm
Neighbors of vasculitis
Neighbors of respiratory hypersensitivity
Neighbors of synovitis
Neighbors of liver disease
Neighbors of prostate cancer
Neighbors of osteolysis
Neighbors of ovarian cancer
Neighbors of hypertension
Neighbors of allograft rejection
Neighbors of epithelial cell
Neighbors of keratinocyte
Neighbors of vascular smooth muscle cell
Neighbors of umbilical vein endothelial cell
Neighbors of monocyte
Neighbors of alveolar macrophage
Neighbors of synoviocyte
Neighbors of macrophage
Neighbors of activated monocyte
Neighbors of fibroblast
Neighbors of airway epithelial cell
Neighbors of PBMC
Neighbors of stromal cell
Neighbors of osteoblast
Neighbors of pneumocyte
Neighbors of endometrium cell
Neighbors of microglia
Neighbors of intestine epithelium cell
Neighbors of mononuclear cell
Neighbors of hepatic stellate cell
Neighbors of hepatocyte
Neighbors of decidual cell
Neighbors of kidney mesangial cell
Neighbors of endothelial cell
Neighbors of dendritic cell
Neighbors of Kuppfer cell
Neighbors of inflammatory cell
Neighbors of bone marrow macrophage
Neighbors of osteoclast
Neighbors of neutrophil
Neighbors of astrocyte
Neighbors of activated T-cell
Neighbors of capillary endothelial cell
Neighbors of immunocompetent cell
Neighbors of granulocyte
Neighbors of cancer-associated fibroblast
Neighbors of myeloid cell
Neighbors of mesenchymal stroma cell
Neighbors of stem cell
Neighbors of tumor infiltrating macrophage
Neighbors of sinusoidal cell
Neighbors of B-cell
Neighbors of leukocyte
Neighbors of insulin-secreting cell
Neighbors of T-cell
Neighbors of M1 macrophage
Neighbors of myofibroblast
Neighbors of mast cell
Neighbors of spleen cell
Neighbors of neuroglia
Neighbors of thyroid epithelial cell
Neighbors of podocyte
Neighbors of conventional dendritic cell
Neighbors of pericyte
Neighbors of epidermis cell
Neighbors of lymphocyte
Neighbors of Langerhans cell
Neighbors of thymic epithelial cell
Neighbors of lymphoid cell
Neighbors of activated B-cell
Neighbors of liver
Neighbors of kidney
Neighbors of skin
Neighbors of intestine
Neighbors of lymph node
Neighbors of heart
Neighbors of gastrointestinal tract
Neighbors of microvessel
Neighbors of placenta
Neighbors of synovial membrane
Neighbors of uterus
Neighbors of islets of Langerhans
Neighbors of left ventricle
Neighbors of glands
Neighbors of eye
Neighbors of NF-kB family
Neighbors of oxidized LDL
Neighbors of IL1 family
Neighbors of PPAR
Neighbors of Jun/Fos
Neighbors of PI3K
Neighbors of mitogen-activated protein kinase
Neighbors of IFNAR ligand
Neighbors of TLR
Neighbors of cytokine
Neighbors of interferon
Neighbors of JAK
Neighbors of ovalbumin
Neighbors of inflammatory cytokine
Neighbors of IL23
Neighbors of T-cell receptor
Neighbors of IL12
Neighbors of prostaglandin-endoperoxide synthase
Neighbors of aldehyde reductase
Neighbors of non-coding RNA
Neighbors of histone H3
Neighbors of STAT5
Neighbors of TORC1
Neighbors of phosphodiesterase
Model of PPARG signaling in psoriasis
PPARG negative regulators and targets
Model of PPARG related pathways in psoriasis (short version)
4_1_Polymorphisms associated with inflammatory bowel diseases

MedScan ID 4283

LocusLink ID 4283

Alias CXC chemokine ligand 9
Gamma interferon induced monokine
monokine induced by IFN-gamma
Small inducible cytokine B9
chemokine CXC ligand 9
C-X-C motif chemokine ligand 9
small inducible cytokine b subfamily (cys-x-cys), member 9
MIG protein
chemokine (C-X-C motif) ligand 9
chemokine CXCL9
Humig
SZ09
small inducible cytokine b subfamily (cys-x-cys), member IX
CXC ligand 9
monokine induced by gamma interferon
MGC105312
C-X-C motif chemokine 9
MIG
CXCL9 chemokine
crg-10
CXCL9
protein MIG
monokine induced by interferon gamma
crg X
M119
SZ09_HUMAN
interferon gamma-induced HuMIG
SCYB9
monokine induced by IFNG
CMK
gamma-interferon-induced monokine
monokine induced by interferon-gamma
small-inducible cytokine B9

GO ID 0048248
0008009
0005125
0007186
0007189
0061844
0007267
0006968
0071222
0070098
0006935
0006952
0051607
0006955
0006954
0030595
0030593
0045663
1901741
0051281
0042127
0007165
0009897
0005576
0005615
0060326
0030816
0043950
0002690
0032496
0010818

KEGG ID hsa:4283

Organism Homo sapiens {Organism urn:agi-taxid:9606}
Homo sapiens

OMIM ID 601704

Hugo ID 7098
HGNC:7098

Human chromosome position 4q21.1
4q21

Swiss-Prot Accession Q07325
Q07325.1
Q503B4

PIR ID JN0470

GenBank ID NC_000004
NM_002416
NP_002407
AC112719
CH471057
EAX05763
EAX05764
AK311852
BAG34794
BC025745
BC042178
BC063122
AAH63122
BC095396
AAH95396
DB141449
X72755
CAA51284
Q07325
NC_018915
AMYH02009503
HQ447615
ADQ32101
AC_000136
ABBA01063355

Swiss-Prot ID CXCL9_HUMAN

Cell Localization Secreted

Ensembl ID ENSG00000138755
ENSP00000354901.4
ENST00000264888.5
ENSP00000354901
ENST00000264888

Unigene ID Hs.77367

Shape Rhomb