Pathway
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Proteins with Altered Expression in Aging
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Necrosis
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Lipids Enhance Apoptotic Cell Engulfment and Reduce Inflammation
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Keep out Signal: LTF Inhibits Neutrophil Recruitment and Inflammation
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Leukotriene Effect on Airway Smooth Muscle Response
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Mast-Cells De Novo Synthesized Mediators via IgE Independent Signaling
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Macrophage Related Iron Uptake and Release
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CD16/CD14 Proinflammatory Monocyte Activation
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anti-Inflammatory Function of Macrophage M2 Lineage
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Nociception Expression Targets Signaling
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NPY1R -> CRH/POMC Production
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NTSR1 Expression Targets
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CRH -> Synthesis of Corticosteroids
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CCR1 Expression Targets
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ADRA1A -> IL6 Production
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ADRB1 -> Prostaglandin Generation
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ADRA1 -> Prostaglandin Generation
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BDKRB1/2 -> Prostaglandin Generation
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BDKRB1/2 -> Interleukins Production
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CNR1/2 -> IL1B/2/4/6/10 Production
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DRD2 Expression Targets
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GALR1/2/3 -> POMC/NPY Production
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HRH2/4 -> IL6/10 Production
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CHRM1 -> IL2 Production
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OPRK -> Pain Perception
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PTGIR -> IL6 Production
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PTGER2/3 -> Inflammation-Related Expression Targets
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HTR1 -> IL6 Production
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HTR7 -> IL6 Production
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HTR5 -> TNF Production
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TACR1 -> TNF/IL6/IL8 Production
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IL6 Expression Targets -> Nociception
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IL1B Expression Targets -> Nociception
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Leptin -> CD25/IL6/IL10 Production
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CHRNA7 -> IL8 Production
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NMDA Receptors -> Ca2+/CREB Activation/PGE2 Synthesis
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P2RY11/13/14 -> IL8/10 Production
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Reperfusion Injury in Myocardial ischemia
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Graves Ophthalmopathy
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Fatty Acids in Hypertension and Atherosclerosis Development
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Antiphospholipid Antibodies in Endothelial Cell
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Antiphospholipid Antibodies and Endothelial Cell Interaction
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SERPINA1 Associated Liver Damage
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TRPM7/8 in Pancreatic Adenocarcinoma
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Airway Epithelial Cell Dysfunction
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Diabetes Induced Periodontitis
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Drugs Targets in Autistic Disoreder (Hypothesis)
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IL6 Promotes Inflammation in Muscular Dystrophies
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Muscular Dystrophies
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Local Estrogen Production in Endometriosis
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Oxidative Stress, All-Trans-Retinal and Lipofuscin Toxicity in AMD
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ER Stress in Macular Degeneration
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Aminoglycosides and Cisplatin Induced Ototoxicity (Mouse Model)
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Cochlear Inflammation (Noise-Induced)
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Glucocorticoid Resistance
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Cyclosporine Induced Nephrotoxicity
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STAT3 and NFkB Activate Inflammation-Induced Tumorigenesis
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IL23A and IL17A Provoke Cancer-Associated Inflammation
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Asbestosis- and Silicosis-Associated Inflammation Provokes Cancer Development
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Proteins with Altered Expression in Tumor-Promoting Inflammation
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N2 Neutrophils in Tumor-Promoting Inflammation and Tumor Progression
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NFKB Signaling Activation by Blocking of Tumor Suppressors
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ROS in Triggering Vascular Inflammation
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cypa
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PPARG inhibits phenotypes assotiated with psoriasis
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Neighbors of inflammation
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Figure 1_Levothyroxine clinical effects
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Figure 1_Levothyroxine clinical effects
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1_Local estrogen production stimulates ectopic endometrium proliferation
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2_Oxidative stress, all-trans-retinal, and lipofuscin toxicity in agerelated macular degeneration
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3_Endoplasmic reticulum stress in age-related macular degeneration
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2_High levels of hepcidin block iron absorption in the gut
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3_Impairment of iron release from splenic macrophages
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1_Inflammatory mediators increase the production of hepcidin (HAMP)
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5_The rationale for the treatment of anemia of chronic disease with erythropoietin
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4_Inflammatory mediators inhibit GATA signaling in erythropoiesis
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2_SERPINA1-associated liver damage
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