URN | urn:agi-llid:64750 |
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Total Entities | 0 |
Connectivity | 653 |
Name | SMURF2 |
Description | SMAD specific E3 ubiquitin protein ligase 2 |
Primary Cell Localization | Cytoplasm |
Pathway | Osteoarthritis |
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TGF-beta Signaling in Skin Aging | |
Proteins Involved in Osteoarthritis | |
TGFB2 Signaling Impairement in Osteoarthritis | |
Proteins with Altered Expression in Osteoarthritis | |
Bone Loss in Osteoporosis | |
Breast Cancer | |
Ovarian Cancer | |
BMP7/ACVR2 Expression Targets | |
TGFB Signaling activation by Blocking of Tumor Suppressors | |
INHBA/ACVR2/ACVR1 Expression Targets | |
TGFBR/BMPR -> SMAD2/3 Signaling | |
ActivinR -> SMAD2/3 Signaling | |
TGFBR1/AP-1 Signaling | |
MSTN/ACVR2/ACVR1 Expression Targets | |
TGF-beta Signaling | |
TGFB2-TGFBR1 Expression Targets | |
TGFB3-TGFBR1 Expression Targets | |
TGFB1-TGFBR1 Expression Targets | |
TGFB1-TGFBR1/AP-1 Expression Targets | |
1_Differentiation of psoriatic T cells | |
3_TGFB signaling provokes endochondral ossification with osteophyte formation | |
Differentiation of psoriatic T cells |
MedScan ID | 64750 |
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LocusLink ID | 64750 |
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66313 | |
303614 |
Alias | SMURF2 |
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MGC138150 | |
HECT-type E3 ubiquitin transferase SMURF2 | |
DKFZp686F0270 | |
2810411E22 | |
smad specific e3 ubiquitin protein ligase 2 | |
hSMURF2 | |
smad specific e3 ubiquitin protein ligase II | |
E3 ubiquitin ligase SMURF2 | |
2810411E22Rik | |
SMAD ubiquitination regulatory factor 2 | |
RP23-170A23.3 | |
AI558114 | |
AI649275 | |
RGD1310067 | |
OTTMUSP00000003747 | |
E3 ubiquitin-protein ligase SMURF2 | |
SMAD-specific E3 ubiquitin-protein ligase 2 |
EC Number | 2.3.2.26 |
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6.3.2.- |
GO ID | 0046332 |
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0005160 | |
0061630 | |
0004842 | |
0030509 | |
0060071 | |
0030514 | |
0000122 | |
0045892 | |
0030512 | |
0090263 | |
0045732 | |
1901165 | |
0043161 | |
0016579 | |
0000209 | |
0016567 | |
0017015 | |
0030579 | |
0006511 | |
0005737 | |
0005829 | |
0045121 | |
0016607 | |
0005654 | |
0005634 | |
0005886 | |
0000151 | |
0016740 | |
0016020 | |
0016874 | |
0042787 | |
0008766 | |
0043773 | |
0043774 | |
0070739 | |
0070735 | |
0070737 | |
0070736 | |
0018169 | |
0070740 | |
0070738 | |
0007179 | |
0010467 | |
0006367 | |
0006351 |
KEGG ID | hsa:64750 |
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mmu:66313 |
Organism | Homo sapiens {Organism urn:agi-taxid:9606} |
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Mus musculus {Organism urn:agi-taxid:10090} | |
Rattus norvegicus {Organism urn:agi-taxid:10116} | |
Homo sapiens | |
Mus musculus | |
Rattus norvegicus |
Mouse chromosome position | 11 |
---|
OMIM ID | 605532 |
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Rat chromosome position | 10q32.1 |
---|
Hugo ID | 16809 |
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HGNC:16809 |
Human chromosome position | 17q23.3-q24.1 |
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17q22-q23 |
Swiss-Prot Accession | Q96DE7 |
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Q9HAU4 | |
Q9HAU4.1 | |
A2A5Z6 | |
Q9CSE3 | |
A2A5Z6.1 | |
Q52LL1 | |
Q9H260 | |
A2A5Z7 | |
Q5IRE6 |
Swiss-Prot ID | SMUF2_HUMAN |
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SMUF2_MOUSE |
Cell Localization | Nucleus |
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Cytoplasm | |
Cell membrane | |
Membrane raft |
Ensembl ID | ENSG00000108854 |
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ENSP00000262435.9 | |
ENST00000262435.14 | |
ENSMUSG00000018363 | |
ENSMUSP00000090177.2 | |
ENSMUST00000092517.8 | |
ENSMUSP00000099356.3 | |
ENSMUST00000103067.9 | |
ENSRNOG00000014623 | |
ENSRNOP00000019781.4 | |
ENSRNOT00000019781.6 | |
ENSP00000262435 | |
ENST00000262435 | |
ENSMUSP00000090177 | |
ENSMUST00000092517 | |
ENSMUSP00000099356 | |
ENSMUST00000103067 | |
ENSRNOP00000019781 | |
ENSRNOT00000019781 |
MGI ID | MGI:1913563 |
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RGD ID | 1310067 |
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Unigene ID | Hs.515011 |
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Mm.340955 | |
Rn.92843 |
Homologene ID | 41490 |
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