Protein MMP9

URN urn:agi-llid:4318
Total Entities 0
Connectivity 17216
Name MMP9
Description matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
Notes Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades type IV and V collagens. Studies in rhesus monkeys suggest that the enzyme is involved in IL-8-induced mobilization of hematopoietic progenitor cells from bone marrow, and murine studies suggest a role in tumor-associated tissue remodeling. [provided by RefSeq, Jul 2008]
Primary Cell Localization Extracellular
ObjectType Protein

Pathway Alzheimer's Disease
Skin Aging
Proplatelet Maturation
Lipoxin A4/FPR2-Related Neutrophil Depression
Neutrophil Activation via Adherence on Endothelial Cells
Nociception Expression Targets Signaling
CCR1 Expression Targets
Extracellular Matrix Turnover
Proteins Involved in Atherosclerosis
Dilated Cardiomyopathy
Proteins Involved in Dilated Cardiomyopathy
Cardiomyocyte Hypertrophy
Hypertrophic Cardiomyopathy
Proteins Involved in Arterial Hypertension
Proteins Involved in Pulmonary Hypertension
Smooth Muscle Cell Dysfunction in Pulmonary Hypertension
Myocardial Remodeling
Myocardial Infarction
Proteins Involved in Myocardial Ischemia
Proteins Involved in Myocarditis
Inflammatory Reaction in Acne Vulgaris
Proteins with Altered Expression in Melanoma
Melanoma
Proteins Involved in Melanoma
IL17 Signaling in Psoriasis
Proteins Involved in Psoriasis
IL22 Induces Keratinocyte Proliferation in Psoriasis
Proteins with Altered Expression in Psoriasis
Proteins Involved in Photoaging
Extracellular Matrix Degradation in Skin Aging
Proteins Involved in Systemic Lupus Erythematosus
Tubular Cell Dysfunction in Progressive Diabetic Nephropathy
Proteins Involved in Diabetic Nephropathy
Mesangial Cell Dysfunction in Diabetic Nephropathy
Hepatic Stellate Cells in non-Alcoholic Fatty Liver Disease
Proteins Involved in Colorectal Neoplasms
Metastatic Colorectal Cancer
Proteins Involved in Ulcerative Colitis
Proteins Involved in B-Cell Chronic Lymphocytic Leukemia
B-Cell Chronic Lymphocytic Leukemia
Osteoclast Activation in Multiple Myeloma
IL6/IGF1/VEGFA Signaling in Multiple Myeloma
Proteins Involved in Multiple Myeloma
Proteins Involved in Hepatocellular Carcinoma
Proteins Involved in Pancreatic Cancer
Neutrophil Degranulation via FPR1/IL8
Proteins Involved in Osteoarthritis
Osteoclast Activation in Psoriatic Arthritis
Synovial Fibroblast Activation in Psoriatic Arthritis
Keratinocyte Activation in Psoriatic Arthritis
Proteins Involved in Rheumatoid Arthritis
Proteins Involved in Systemic Scleroderma
Skin Fibrosis
Cathepsins Role in Periodontitis
Estrogen Effects on Pregnancy Gingivitis
Proteins Involved in Periodontitis
Proteins Involved in Fragile X Syndrome
Muscular Dystrophies
Proteins Involved in Alzheimer's Disease
Amyloid beta Traffic and Degradation in Extracellular Matrix in Alzheimer's Disease
Proteins Involved in Epilepsy
Proteins Involved in Glioblastoma
Glioma Invasion Signaling
Proteins Involved in Glioma
Proteins Involved in Medulloblastoma
Proteins Involved in Neuroblastoma
Proteins Involved in Amyotrophic Lateral Sclerosis
Proteins Involved in Multiple Sclerosis
Proteins Involved in Breast Cancer Related to WNT Signaling Pathway
Proteins Involved in Breast Cancer Related to ESR1 Signaling Pathway
Proteins Involved in Breast Cancer Related to NOTCH Signaling Pathway
WNT Signaling in Breast Cancer
Proteins Involved in Breast Cancer Related to ERBB2/VEGFR/Akt Signaling Pathway
Proteins with Altered Expression in Breast Cancer
Proteins Involved in Breast Cancer Related to IGF1R/Akt Signaling Pathway
NOTCH1 Signaling in Breast Cancer
Proteins Involved in Adhesion, Migration and Invasion of Endometriotic Cell
Proteins Involved in Endometriosis
Proteins with Altered Expression in Endometriosis
Proteins Involved in Cholesteatoma
MIF Role in Cholesteatoma
Cholesteatoma
Prostate Cancer
Proteins Involved in Prostate Cancer
Netrin-1 Signaling in Age-Related Macular Degeneration
Proteins Involved in Age-Related Macular Degeneration
Proteins Involved in Cataract
Proteins with Altered Expression in Cataract
Steroids Induced Cataract
Proteins Involved in Glaucoma
PGF2-alpha Effect on Treatment
Proteins Involved in Otitis Media
Proteins with Altered Expression in Asthma
Alveolar Macrophages Dysfunction in COPD
Proteins Involved in Chronic Obstructive Pulmonary Disease
Neutrophil Associated Lung Damage in Chronic Obstructive Pulmonary Disease
Proteins Involved in Glomerulonephritis
Mesangial Cell Dysfunction in Glomerulonephritis
Interstitial Fibroblasts in Pyelonephritis
HMGB1 Expression Targets
ANGPT2 -> AP-1/CREBBP/MYC Expression Targets
AREG -> CTNN Expression Targets
AREG -> STAT Expression Targets
AREG -> AP-1 Expression Targets
Noradrenaline/Gs Expression Targets
Noreadrenaline/Gq Expression Targets
Acetylcholine Expression Targets
BMP6/ACVR2A Expression Targets
BTC -> NFATC Expression Targets
BTC -> AP-1/ATF/CREB Expression Targets
BTC -> CTNN Expression Targets
BTC -> STAT Expression Targets
BTC -> EP300/ETS/ETV/SP1 Expression Targets
Elevated Receptors -> Expression Targets in Joint
Receptor Tyrosine Kinase Family -> Expression Targets in Bone
GPCRs Family -> Expression Targets in Bone
Elevated Receptors -> Expression Targets in Bone
CD86 -> NFATC Expression Targets
Elevated Receptors -> Expression Targets in Blood vessel
Elevated Receptors -> Expression Targets in Blood Vessel
CXCL1 Expression Targets
CXCL12 Expression Targets
CCL3 Expression Targets
CCL7 Expression Target
CCL7 Expression Targets
CCL8 Expression Targets
IL8 Expression Targets
CSF3 Expression Targets
CSF2 -> STAT Expression Targets
EGF -> CTNN Expression Targets
EGF -> AP-1/ATF Expression Targets
EGF -> CREB/CREBBP/ELK/SRF/MYC Expression Targets
EGF -> MEF/MYOD/NFATC Expression Targets
EGF -> STAT Expression Targets
Erythropoietin -> NF-kB Expression Targets
Erythropoietin -> AP-1/MYC/CREB Expression Targets
Erythropoietin -> STAT Expression Targets
Erythropoietin -> ELK/SRF Expression Targets
F2 -> AP-1/CREB/ELK/SRF/SP1 Expression Targets
F2 -> STAT1/NF-kB Expression Targets
FGF2 -> STAT Expression Targets
FGF1 -> AP-1/CREB/ELK/SRF/MYC Expression Targets
FGF8 -> AP-1/CREB/MYC Expression Targets
FGF1 -> STAT Expression Targets
FGF8 -> STAT Expression Targets
FGF8 -> RUNX Expression Targets
FGF2 -> AP-1/CREB/CREBBP/ELK/SRF/MYC Expression Targets
ADCYAP1 Expression Targets
Elevated Receptors -> Expression Targets in Liver
HGF -> STAT Expression Targets
HGF -> AP-1/CREB/ELK/SRF/MYC Expression Targets
EGFR Transactivation in Cancer and Non-Cancer Cells
TAM Receptor Signaling Activation in Cancer
STAT3 and NFkB Activate Inflammation-Induced Tumorigenesis
IL13/STAT6/ZEB1 Signalling Promotes Cancer Metastatic Progression
N2 Neutrophils in Tumor-Promoting Inflammation and Tumor Progression
Oxidized LDL/OLR1 Activates Cell Proliferation in Cancer
Inhibition of THBS1 Activates Angiogenesis in Cancer
Integrins in Cancer Cell Motility, Invasion and Survival
Proteins with Altered Expression in Cancer Metastases
Epithelial to Mesenchymal Transition in Cancer: Overview
BSG (CD147) in Cancer Cells Motility, Invasion and Survival
MTOR/TORC in Cancer Cell Motility and Invasion
TGFB Family in Epithelial to Mesenchymal Transition in Cancer
Invadopodia Formation in Cancer Cells
WNT in Epithelial to Mesenchymal Transition in Cancer
Tumor Infiltrating Macrophages in Cancer Progression and Immune Escape
INHBA/ACVR2/BMPR Expression Targets
INHBA/ACVR2/ACVR1 Expression Targets
Insulin -> STAT Expression Targets
Insulin -> CEBPA/CTNNB/FOXA/FOXO Expression Targets
Insulin -> MEF/MYOD Expression Targets
Insulin -> ELK/SRF/HIF1A/MYC/SREBF Expression Targets
Fibronectin Expression Targets
CTGF -> AP-1/CREB/MYC Expression Targets
ICAM1 Expression Targets
EGFR -> Expression Targets in Skin
Elevated Receptors -> Expression Targets in Skin
IFNG/IFNR Expression Targets
IL13 Expression Targets
IL21 Expression Targets
IL6 Expression Targets
IL11 Expression Targets
IL4 Expression Targets
IL2 Expression Targets
Leptin -> STAT Expression Targets
Leptin -> ELK/SRF Expression Targets
Prostaglandin F Expression Targets
PAF/Gq -> AP-1/ATF1/CREB/ERK/SRF Expression Targets
S1P Expression Targets
PGE1 Expression Targets
EGFR-> Expression Targets in Lymphoid System and Blood
Elevated Receptors -> Expression Targets in Lymph Node
Elevated Receptors -> Expression Targets in Lymphoid System and Blood
F2R/F2RL1 -> Expression Targets in Lymphoid System and Blood
CD Markers -> Expression Targets in Lymphoid System and Blood
GPCRs Family -> Expression Targets in Lymphoid System and Blood
Cell Adhesion Receptors -> Expression Targets in Lymphoid System and Blood
Immunoglobulin Superfamily -> Expression Targets in Lymphoid System and Blood
Elevated Receptors -> Expression Targets in Bone Marrow
Interleukin Receptors -> Expression Targets in Lymphoid System and Blood
C5AR1 -> Expression Targets in Lymphoid System and Blood
Chemokine Receptor Family -> Expression Targets in Lymphoid System
NRG1 -> EP300/ETS/ETV/SP1 Expression Targets
NRG1 -> CREB/CREBBP/ELK/SRF/MYC Expression Targets
NRG1/Catenin Expression Targets
NRG1 -> STAT Expression Targets
NRG1 -> AP-1/ATF Expression Targets
Elevated Receptors -> Expression Targets in Nerve Tissue
NGF -> SMAD3/NF-kB Expression Targets
NGF -> AP-1/TP53/MYC Expression Targets
NOTCH Expression Targets
PDGFD -> AP-1 Expression Targets
PDGFD -> STAT Expression Targets
PDGF -> AP-1/CREB/CREBBP/MYC Expression Targets
PDGF -> STAT Expression Targets
GNRH1 Expression Targets
NTS Expression Targets
GAST Expression Targets in GAST Expression Targets
EDN1 Expression Targets
AGT -> CREB Expression Targets
AGT -> STAT Expression Targets
AVP/Gq -> CREB/ELK/SRF/AP-1/EGR Expression Targets
PRL/GHR -> STAT Expression Targets
PRL/GHR -> NF/kB/ELK/SRF/MYC Expression Targets
KITLG -> STAT Expression Targets
KITLG -> AP-1/CREB/CREBBP/MYC Expression Targets
EphrinR Expression Targets
GDNF -> HSF1 Expression Targets
PAF Expression Targets
PGF -> AP-1/CREB/CREBBP/MYC Expression Targets
Elevated Receptors -> Expression Targets in Breast
Elevated Receptors -> Expression Targets in Uterus
Elevated Receptors -> Expression Targets in Lung
TGFA -> STAT Expression Targets
TGFA -> CTNNB/CTNND Expression Targets
TGFA/AP-1/ATF Expression Targets
TGFA -> CREB/CREBBP/ELK-SRF/MYC Expression Targets
TGFB3-TGFBR1 Expression Targets
TGFB1-TGFBR1 Expression Targets
TGFB3-TGFBR2 Expression Targets
TGFB1-TGFBR2 Expression Targets
TGFB1-TGFBR1/AP-1 Expression Targets
TGFB1-ACVRL1 Expression Targets
TNF -> NF-kB Expression Targets
TNFSF10 Expression Targets
LTA Expression Targets
TNF -> AP-1 Expression Targets
CD72 -> AP-1 Expression Targets
CD40LG -> STAT Expression Targets
CD40LG -> NF-kB/ELK/SRF -> CREB/NFATC Expression Targets
TNF -> STAT Expression Targets
TLR3 Expression Targets
TLR4 -> AP-1 Expression Targets
TLR5 Expression Targets
IL1B -> NO Expression Targets
IL1B -> PGE2 Expression Targets
IL1B Expression Targets
IL1A Expression Targets
TLR9 Expression Targets
ROS in Triggering Vascular Inflammation
ROS in Angiotensin Mediated Cardiovascular Remodeling and Hypertrophy
PLAU -> STAT1 Expression Targets
PLAU -> ELK-SRF/AP-1 Expression Targets
VEGFA -> ATF/CREB/ELK-SRF Expression Targets
VEGFA -> STAT Expression Targets
VEGFA -> AP-1/CREBBP/MYC Expression Targets
VEGFA -> CTNNB/CTNND Expression Targets
WNT5A Expression Targets
WNT Canonical Signaling Expression Targets
pprarg neg, uknown targets, ps-positive
prarg neg,ukn expres targets, ps-positive
PPARG negative targets
pparg expr target_regulators
Neighbors of disease exacerbation
Neighbors of tumor progression
Neighbors of cancer progression
Neighbors of inflammatory status
Neighbors of overall survival
Neighbors of disease severity
Neighbors of tumor size
Neighbors of lesion size
Neighbors of mortality
Neighbors of survival rate
Neighbors of infarct size
Neighbors of survival time
Neighbors of functional recovery
Neighbors of insulin sensitivity
Neighbors of bacterial load
Neighbors of cancer survival
Neighbors of graft survival
Neighbors of therapeutic efficacy
Neighbors of clinical stage
Neighbors of lethality
Neighbors of tumor regression
Neighbors of recurrence-free survival
Neighbors of disease-free survival
Neighbors of tumor response
Neighbors of macrophage count
Neighbors of treatment outcome
Neighbors of body weight gain
Neighbors of cardiovascular risk
Neighbors of microvessel density
Neighbors of tumor recurrence
Neighbors of tumor promotion
Neighbors of neutrophil count
Neighbors of morbidity
Neighbors of mortality rate
Neighbors of bone mineral density
Neighbors of adverse outcome
Neighbors of radioresistance
Neighbors of lesion area
Neighbors of cell density
Neighbors of cancer-specific survival
Neighbors of progression-free survival
Neighbors of shear stress
Neighbors of viral load
Neighbors of blood pressure
Neighbors of tumor grade
Neighbors of vascular reactivity
Neighbors of vascular leakage
Neighbors of body mass index
Neighbors of vascular density
Neighbors of cancer risk
Neighbors of cancer incidence
Neighbors of tumor aggressiveness
Neighbors of blood glucose
Neighbors of ejection fraction
Neighbors of renal hypertrophy
Neighbors of cancer recurrence
Neighbors of antimetastatic activity
Neighbors of glucose level
Neighbors of vascular tone
Neighbors of left ventricular ejection fraction
Neighbors of breast cancer risk
Neighbors of proliferation index
Neighbors of cell permeability
Neighbors of pregnancy outcome
Neighbors of functional status
Neighbors of neurological outcome
Neighbors of infarct area
Neighbors of fertility
Neighbors of recurrence rate
Neighbors of pathological response
Neighbors of skin thickness
Neighbors of carotid intima-media thickness
Neighbors of fibroblast phenotype
Neighbors of disease exacerbation
Neighbors of tumor progression
Neighbors of cancer progression
Neighbors of inflammatory status
Neighbors of overall survival
Neighbors of disease severity
Neighbors of tumor size
Neighbors of lesion size
Neighbors of mortality
Neighbors of survival rate
Neighbors of infarct size
Neighbors of survival time
Neighbors of functional recovery
Neighbors of insulin sensitivity
Neighbors of bacterial load
Neighbors of cancer survival
Neighbors of graft survival
Neighbors of therapeutic efficacy
Neighbors of clinical stage
Neighbors of lethality
Neighbors of tumor regression
Neighbors of recurrence-free survival
Neighbors of disease-free survival
Neighbors of tumor response
Neighbors of macrophage count
Neighbors of treatment outcome
Neighbors of body weight gain
Neighbors of cardiovascular risk
Neighbors of microvessel density
Neighbors of tumor recurrence
Neighbors of tumor promotion
Neighbors of neutrophil count
Neighbors of morbidity
Neighbors of mortality rate
Neighbors of bone mineral density
Neighbors of adverse outcome
Neighbors of radioresistance
Neighbors of lesion area
Neighbors of cell density
Neighbors of cancer-specific survival
Neighbors of progression-free survival
Neighbors of shear stress
Neighbors of viral load
Neighbors of blood pressure
Neighbors of tumor grade
Neighbors of vascular reactivity
Neighbors of vascular leakage
Neighbors of body mass index
Neighbors of vascular density
Neighbors of cancer risk
Neighbors of cancer incidence
Neighbors of tumor aggressiveness
Neighbors of blood glucose
Neighbors of ejection fraction
Neighbors of renal hypertrophy
Neighbors of cancer recurrence
Neighbors of antimetastatic activity
Neighbors of glucose level
Neighbors of vascular tone
Neighbors of left ventricular ejection fraction
Neighbors of breast cancer risk
Neighbors of proliferation index
Neighbors of cell permeability
Neighbors of pregnancy outcome
Neighbors of functional status
Neighbors of neurological outcome
Neighbors of infarct area
Neighbors of fertility
Neighbors of recurrence rate
Neighbors of pathological response
Neighbors of skin thickness
Neighbors of carotid intima-media thickness
Neighbors of fibroblast phenotype
Neighbors of cell development
Neighbors of immune response
Neighbors of cell population
Neighbors of inflammatory response
Neighbors of wound healing
Neighbors of angiogenesis
Neighbors of innate immune response
Neighbors of cell function
Neighbors of cell formation
Neighbors of adaptive immune response
Neighbors of osteoclast development
Neighbors of epithelial to mesenchymal transition
Neighbors of immunity
Neighbors of cell proliferative response
Neighbors of chemotaxis
Neighbors of dendritic cell differentiation
Neighbors of cell survival
Neighbors of osteoclast differentiation
Neighbors of cell phenotype
Neighbors of T-cell proliferation
Neighbors of tissue remodeling
Neighbors of cell adhesion
Neighbors of T-cell activation
Neighbors of endothelial cell proliferation
Neighbors of fibrogenesis
Neighbors of tumor growth
Neighbors of dendritic cell development
Neighbors of tissue repair
Neighbors of cell count
Neighbors of cell infiltration
Neighbors of cell interaction
Neighbors of SMC proliferation
Neighbors of lumen formation
Neighbors of endothelial cell migration
Neighbors of adipogenesis
Neighbors of lipid storage
Neighbors of cell damage
Neighbors of pregnancy
Neighbors of monocyte differentiation
Neighbors of aging
Neighbors of cell motility
Neighbors of bone resorption
Neighbors of monocyte migration
Neighbors of fibroblast proliferation
Neighbors of adipocyte differentiation
Neighbors of macrophage migration
Neighbors of microglial activation
Neighbors of neutrophil recruitment
Neighbors of regeneration
Neighbors of cell migration
Neighbors of cancer growth
Neighbors of stem cell proliferation
Neighbors of smooth muscle cell migration
Neighbors of hepatic regeneration
Neighbors of transendothelial migration
Neighbors of phagocytosis
Neighbors of leukocyte migration
Neighbors of leukocyte recruitment
Neighbors of osteoclast formation
Neighbors of monocyte recruitment
Neighbors of cell invasion
Neighbors of heart function
Neighbors of hemopoiesis
Neighbors of bone remodeling
Neighbors of ossification
Neighbors of immune system function
Neighbors of lung development
Neighbors of autophagy
Neighbors of monocyte adhesion
Neighbors of transcription activation
Neighbors of senescence
Neighbors of T-cell response
Neighbors of hepatocyte proliferation
Neighbors of cell transdifferentiation
Neighbors of neuroprotection
Neighbors of stem cell differentiation
Neighbors of endothelial cell function
Neighbors of neuronal death
Neighbors of cell growth
Neighbors of ROS generation
Neighbors of epithelial cell proliferation
Neighbors of first trimester pregnancy
Neighbors of cancer cell growth
Neighbors of sensitization
Neighbors of hemato-encephalic barrier
Neighbors of macrophage function
Neighbors of cellular senescence
Neighbors of colony formation
Neighbors of macrophage differentiation
Neighbors of cell differentiation
Neighbors of stem cell migration
Neighbors of life span
Neighbors of cell homeostasis
Neighbors of psoriasis
Neighbors of inflammatory disease
Neighbors of rheumatoid arthritis
Neighbors of atherosclerosis
Neighbors of fibrosis
Neighbors of colitis
Neighbors of arthritis
Neighbors of inflammatory bowel disease
Neighbors of injury
Neighbors of atherogenesis
Neighbors of vascular remodeling
Neighbors of metastasis
Neighbors of carcinogenesis
Neighbors of multiple sclerosis
Neighbors of chronic inflammation
Neighbors of inflammation
Neighbors of tumor microenvironment
Neighbors of pathological angiogenesis
Neighbors of obesity
Neighbors of vascular disease
Neighbors of diabetes mellitus
Neighbors of asthma
Neighbors of pneumonia
Neighbors of hyperplasia
Neighbors of osteoarthritis
Neighbors of liver fibrosis
Neighbors of chronic obstructive pulmonary disease
Neighbors of myocardial infarction
Neighbors of leukocyte infiltration
Neighbors of reperfusion injury
Neighbors of airway inflammation
Neighbors of hepatitis
Neighbors of insulin resistance
Neighbors of infection
Neighbors of vascular injury
Neighbors of renal injury
Neighbors of preeclampsia
Neighbors of macrophage infiltration
Neighbors of liver injury
Neighbors of neuroinflammation
Neighbors of sepsis
Neighbors of death
Neighbors of type 1 diabetes
Neighbors of encephalomyelitis
Neighbors of autoimmune disease
Neighbors of ischemic stroke
Neighbors of dermatitis
Neighbors of neutrophil infiltration
Neighbors of heart disease
Neighbors of diabetic nephropathy
Neighbors of lung injury
Neighbors of immunopathology
Neighbors of systemic sclerosis
Neighbors of hepatocellular carcinoma
Neighbors of autoimmunity
Neighbors of acute lung injury
Neighbors of gastric cancer
Neighbors of atherosclerotic plaque
Neighbors of experimental autoimmune encephalomyelitis
Neighbors of colorectal cancer
Neighbors of cardiac remodeling
Neighbors of breast cancer
Neighbors of ischemia
Neighbors of systemic lupus erythematosus
Neighbors of melanoma
Neighbors of collagen-induced arthritis
Neighbors of cartilage degeneration
Neighbors of interstitial fibrosis
Neighbors of neoplasm invasion
Neighbors of kidney disease
Neighbors of heart failure
Neighbors of lung disease
Neighbors of pulmonary fibrosis
Neighbors of cardiovascular disease
Neighbors of stroke
Neighbors of cancer
Neighbors of cerebral ischemia
Neighbors of type 2 diabetes
Neighbors of neoplasm
Neighbors of endometriosis
Neighbors of neointima
Neighbors of vasculitis
Neighbors of atrophy
Neighbors of respiratory hypersensitivity
Neighbors of myocardial fibrosis
Neighbors of coronary artery disease
Neighbors of rupture
Neighbors of endothelial cell dysfunction
Neighbors of liver disease
Neighbors of prostate cancer
Neighbors of hypertrophy
Neighbors of osteolysis
Neighbors of ovarian cancer
Neighbors of pancreatic cancer
Neighbors of hypertension
Neighbors of intimal hyperplasia
Neighbors of proteinuria
Neighbors of epithelial cell
Neighbors of keratinocyte
Neighbors of vascular smooth muscle cell
Neighbors of umbilical vein endothelial cell
Neighbors of monocyte
Neighbors of endometrial stromal cell
Neighbors of alveolar macrophage
Neighbors of synoviocyte
Neighbors of macrophage
Neighbors of adipocyte
Neighbors of activated monocyte
Neighbors of fibroblast
Neighbors of airway epithelial cell
Neighbors of PBMC
Neighbors of stromal cell
Neighbors of airway smooth muscle cell
Neighbors of osteoblast
Neighbors of pneumocyte
Neighbors of endometrium cell
Neighbors of microglia
Neighbors of trophoblast
Neighbors of intestine epithelium cell
Neighbors of mononuclear cell
Neighbors of hepatic stellate cell
Neighbors of hepatocyte
Neighbors of decidual cell
Neighbors of kidney mesangial cell
Neighbors of endothelial cell
Neighbors of dendritic cell
Neighbors of Kuppfer cell
Neighbors of proadipocyte
Neighbors of kidney tubule cell
Neighbors of inflammatory cell
Neighbors of bone marrow macrophage
Neighbors of peritoneal macrophage
Neighbors of osteoclast
Neighbors of neutrophil
Neighbors of smooth muscle myocyte
Neighbors of astrocyte
Neighbors of bone marrow derived dendritic cell
Neighbors of lung fibroblast
Neighbors of activated T-cell
Neighbors of mesothelial cell
Neighbors of mononuclear phagocyte
Neighbors of capillary endothelial cell
Neighbors of immunocompetent cell
Neighbors of granulocyte
Neighbors of cardiac myocyte
Neighbors of cancer-associated fibroblast
Neighbors of myeloid cell
Neighbors of mesenchymal stroma cell
Neighbors of corneal epithelial cell
Neighbors of cytotrophoblast
Neighbors of stem cell
Neighbors of tumor infiltrating macrophage
Neighbors of sinusoidal cell
Neighbors of B-cell
Neighbors of granulosa cell
Neighbors of leukocyte
Neighbors of chondrocyte
Neighbors of mesenchymal cell
Neighbors of T-cell
Neighbors of M1 macrophage
Neighbors of myofibroblast
Neighbors of pancreatic stellate cell
Neighbors of mast cell
Neighbors of bone marrow stromal cell
Neighbors of spleen cell
Neighbors of brain capillary endothelial cell
Neighbors of neuroglia
Neighbors of aortic smooth muscle cell
Neighbors of hematopoietic cell
Neighbors of adipose macrophage
Neighbors of podocyte
Neighbors of mammary epithelial cell
Neighbors of conventional dendritic cell
Neighbors of pericyte
Neighbors of antigen-presenting cell
Neighbors of epidermis cell
Neighbors of phagocyte
Neighbors of syncytiotrophoblast
Neighbors of lymphocyte
Neighbors of Langerhans cell
Neighbors of brain cell
Neighbors of M2 macrophage
Neighbors of lymphoid cell
Neighbors of retina cell
Neighbors of blood cell
Neighbors of skin cell
Neighbors of luteal cell
Neighbors of peripheral lymphocyte
Neighbors of activated B-cell
Neighbors of lung
Neighbors of liver
Neighbors of kidney
Neighbors of skin
Neighbors of intestine
Neighbors of lymph node
Neighbors of colon
Neighbors of airway
Neighbors of blood vessel
Neighbors of heart
Neighbors of aorta
Neighbors of microvessel
Neighbors of bone
Neighbors of placenta
Neighbors of carotid artery
Neighbors of synovial membrane
Neighbors of uterus
Neighbors of esophagus
Neighbors of periodontium
Neighbors of retina
Neighbors of brain
Neighbors of ovary
Neighbors of breast
Neighbors of blood vessel wall
Neighbors of stomach
Neighbors of islets of Langerhans
Neighbors of artery
Neighbors of cardiovascular system
Neighbors of central nervous system
Neighbors of kidney glomerulus
Neighbors of colorectal region
Neighbors of decidua
Neighbors of amnion
Neighbors of immune system
Neighbors of spleen
Neighbors of peritoneum
Neighbors of allantois
Neighbors of alveolus
Neighbors of coronary artery
Neighbors of left ventricle
Neighbors of uterine cervix
Neighbors of vein
Neighbors of arteriole
Neighbors of villus
Neighbors of bronchus
Neighbors of glands
Neighbors of nose
Neighbors of eye
Neighbors of cornea
Neighbors of hippocampus
Neighbors of intervertebral disc
Neighbors of vagina
Neighbors of vitreous body
Neighbors of cerebral cortex
Neighbors of brain blood vessel
Neighbors of myelin sheath
Neighbors of nervous system
Neighbors of periodontal ligament
Neighbors of trachea
Neighbors of corpus luteum of ovary
Neighbors of lower extremity
Neighbors of amniotic cavity
Neighbors of lymphatic vessels
Neighbors of left atrium
Neighbors of artery wall
Neighbors of NF-kB family
Neighbors of oxidized LDL
Neighbors of JNK
Neighbors of IL1 family
Neighbors of PPAR
Neighbors of Jun/Fos
Neighbors of NFKBI
Neighbors of PKC
Neighbors of PI3K
Neighbors of STAT family
Neighbors of mitogen-activated protein kinase
Neighbors of IFNAR ligand
Neighbors of transforming growth factor
Neighbors of TLR
Neighbors of cytokine
Neighbors of interferon
Neighbors of interleukin
Neighbors of JAK
Neighbors of MEK1/2
Neighbors of PDGF
Neighbors of Ras GTPase
Neighbors of ERK1/2
Neighbors of growth factor
Neighbors of PKA
Neighbors of ovalbumin
Neighbors of LDL
Neighbors of NF-AT family
Neighbors of beta adrenoceptor
Neighbors of chorionic gonadotropin
Neighbors of IKBK
Neighbors of protein tyrosine kinase
Neighbors of NAD(P)H oxidase
Neighbors of IgG
Neighbors of SMAD subfamily
Neighbors of AMPK
Neighbors of LXR
Neighbors of HDL
Neighbors of p38
Neighbors of inflammatory cytokine
Neighbors of IL23
Neighbors of estrogen receptor
Neighbors of T-cell receptor
Neighbors of histone deacetylase
Neighbors of PDGF-BB
Neighbors of IL1R
Neighbors of HIF-1
Neighbors of GPCR
Neighbors of IL12
Neighbors of Notch
Neighbors of prostaglandin-endoperoxide synthase
Neighbors of heat shock protein 90
Neighbors of lectin
Neighbors of mitogen-activated protein kinase kinase
Neighbors of interleukin-35
Neighbors of TSH
Neighbors of endothelin
Neighbors of NOS
Neighbors of superoxide dismutase
Neighbors of proteasome endopeptidase complex
Neighbors of class nuclear receptor with C4 zinc fingers
Neighbors of non-coding RNA
Neighbors of histone H3
Neighbors of STAT5
Neighbors of alpha2 adrenoceptor
Neighbors of vitronectin receptor (integrin)
Neighbors of PP2A
Neighbors of retinoid-X receptor subfamily
Neighbors of SAPK
Neighbors of WNT
Neighbors of immunoglobulin
Neighbors of phospholipase
Neighbors of AHR subfamily
Neighbors of ITG
Neighbors of relaxin
Neighbors of FSH
Neighbors of TORC1
Neighbors of RA receptor
Neighbors of histone
Neighbors of Rho kinase
Neighbors of PDGF receptor
Neighbors of neuropeptides
Neighbors of pancreatic elastase
Neighbors of histone acetyltransferase
Neighbors of adrenoceptor
Neighbors of caspase
Neighbors of phosphoinositide phospholipase C
Neighbors of deacetylase
comon ps_pos, pprarg_neg targets
sars-cov no binding
Overview. Diseases of the digestive system (chapter 10)
Overview. Diseases of the respiratory (chapter 9)
1_Inflammation in keratinocytes in the pathology of acne
2_Interleukin-17 and interleukin-22 signaling in psoriasis
1_Osteoclast functional impairment in osteopetrosis
3_The role of interstitial fibroblasts in pyelonephritis
3_Mesangial cell dysfunction in glomerulonephritis
2_Cardiomyocyte hypertrophy
2_The intense proliferation and contractile activity of smooth muscle cells in pulmonary hypertension
3_Role of alveolar macrophages in pulmonary tissue destruction in COPD
2_3_Eosinophilia and neutrophilia in asthma: Neutrophil chemotaxis and activation
1_Intestine epithelial cell dysfunction in ulcerative colitis
1_cd_Amyloid-beta in Alzheimer's disease
drug-target moltransport
Interleukin-17 and interleukin-22 signaling in psoriasis

Group Genes with Polymorphisms Associated with Migraine
Genes with Mutations Associated with Multiple Sclerosis
other partners for SARS

MedScan ID 4318

LocusLink ID 4318
17395
81687

Alias Gel B
92kD gelatinase
macrophage gelatinase
matrix metalloprotease 9
92-kDa type IV collagenases
95 kDa type gelatinases
matrix metalloproteinase 9
collagenase type IVB
92kDa collagenase IV
95 kDa type IV collagenase/gelatinase
matrix metallopeptidase 9
collagenase type V
92kDa gelatinase
MMP9
GelB
92kD type IV collagenase
collagenase type 5
MANDP2
AW743869
type V collagenases
OTTHUMP00000031674
pro-gelatinase B
proMMP9
pro-MMP9
type V collagenase
92kDa type IV collagenase
RP23-61O3.10-001
gelatinase B
progelatinase B
3.4.24.35
92-kDa gelatinases
OTTMUSP00000001145
CLG4B
macrophage gelatinases
RP23-61O3.10
MMP-9
matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
matrix metalloproteinase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
matrix metalloproteinase-9
B/MMP9
pro-MMP-9
92 kDa gelatinase
92 kDa type IV collagenase
92-kDa type IV collagenase
matrix metalloproteinase 9 (gelatinase B, 92-kDa type IV collagenase)
matrix metalloproteinase 9 (gelatinase B 92-kDa type IV collagenase)
matrix metalloproteinase 9 (gelatinase b)
matrix metalloprotease 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
matrix metalloproteinase 9 (gelatinase B, 92kD gelatinase, 92kD type IV collagenase)
matrix metalloprotease 9 (gelatinase b)
matrix metalloprotease 9 (gelatinase B, 92kD gelatinase, 92kD type IV collagenase)
matrix metalloprotease 9 (gelatinase B 92-kDa type IV collagenase)
2 kDa 9 type IV collagenase
92 kDa gelatinase
matrix metalloproteinase 9 preproprotein
B/MMP9s

EC Number 3.4.24.35

GO ID 0005518
0004175
0004222
0008237
0004252
0008270
0071276
0034614
0030574
0019221
0007566
0035987
0048013
0022617
0030198
0030225
0043066
2001258
2001268
2000697
2001243
0043312
0043388
0030335
0045742
0051549
0001934
1900122
0090200
1904707
0006508
0150077
1904645
0001501
0062023
0070062
0005576
0005615
1904813
1904724
0001968
0016787
0046872
0008233
0044877
0007568
0071460
0007507
0048147
0045766
0043065
0002687
0031915
0051259
0042493
0006979
0048771
0019087
0031012
0032991
0071345
0071347
0071283
0071222
0071404
0071356
0001822
0050900
0001503
0007567
0032355
0045471
0009408
0009644
0055093
0001666
0032496
0009612
0035094
0007584
0014070
0010033
0009314
0032526
0034612
0033189
0005578
0032403
0043234
0007411
0060033
0016049
0008152
0005509
0005515

KEGG ID hsa:4318
mmu:17395
rno:81687

Organism Homo sapiens {Organism urn:agi-taxid:9606}
Mus musculus {Organism urn:agi-taxid:10090}
Rattus norvegicus {Organism urn:agi-taxid:10116}
Homo sapiens
Mus musculus
Rattus norvegicus

Mouse chromosome position 2 85.27 cM
2 96.0 cM

OMIM ID 120361
613073
603932

Rat chromosome position 3q42

Hugo ID 7176
HGNC:7176

Human chromosome position 20q13.12
20q11.2-q13.1

Swiss-Prot Accession P14780
P14780.3
P41245
P41245.2
P50282
P50282.1
B2R7V9
Q3LR70
Q8N725
Q9H4Z1
Q9UCJ9
Q9UCL1
Q9UDK2
Q06788
Q80XI8
Q9DC02
Q9Y354
Q2M4J5
Q3TTU7
Q3UQ52
Q6GXA2
Q91ZS5
Q9QWS6

PIR ID A34458
I52580
JC1456
JC4364
S62907

GenBank ID NC_000020
NM_004994
NP_004985
NG_011468
AF148064
AAD37404
AF538844
AAM97934
AL162458
AX011001
CAC07541
CH471077
EAW75776
D10051
BAA20967
DQ194553
ABA03169
S83357
AK298246
BAH12743
AK301446
BAH13483
AK302530
BAH13736
AK303080
BAH13895
AK311648
AK313137
BAG35956
AK316145
BAH14516
AW468235
BC006093
AAH06093
CN288579
HQ874462
AEA49029
J05070
AAA51539
P14780
NC_000068
XM_006498861
XP_006498924
NM_013599
NP_038627
AF000957
AAC53571
AF403768
AAK97498
AJ010318
CAA09087
AL591495
AY902320
AAX90605
CH466551
EDL06438
D15060
BAA03653
X72794
CAA51314
AK004651
BAB23442
AK142787
BAE25191
AK159292
BAE34968
AK161176
BAE36227
AY622969
AAT46400
BC046991
AAH46991
BX524519
D12712
BAA02208
S67830
AAB28942
X72795
CAA51315
Z27231
CAA81745
P41245
NC_005102
NM_031055
NP_112317
AC_000071
AABR07054570
AAHX01026383
AJ438266
CAD27893
CH474005
EDL96479
U24441
AAA90911
U36476
AAB01721
P50282
NC_018931
AMYH02037155
AMYH02037156
M68351
M68355
DQ896791
ABM87790
EU176415
ABW03866
AC_000024
AAHY01012603
AC_000152
ABBA01052673
ABBA01052674
CAC10459
CAM26464
CAM26465
NT_011362
NW_927339
NW_001838666
AC_000063
Q9Y354
NT_039207
NW_001030712
Q2M4J5
Q3TTU7
Q3UQ52
Q6GXA2
Q80XI8
Q91ZS5
Q9QWS6
NW_001084817
NW_047660
Q9UCJ9

Swiss-Prot ID MMP9_HUMAN
MMP9_MOUSE
MMP9_RAT
Q80XI8_MOUSE

Cell Localization Secreted
Extracellular space
Extracellular matrix
Extracellular
Secreted, extracellular space, extracellular matrix

Ensembl ID ENSG00000100985
ENSP00000361405.3
ENST00000372330.3
ENSMUSG00000017737
ENSMUSP00000017881.2
ENSMUST00000017881.2
ENSRNOG00000017539
ENSRNOP00000023965.1
ENSRNOT00000023965.3
ENSP00000361405
ENST00000372330
ENSMUSP00000017881
ENSMUST00000017881
ENSRNOP00000023965
ENSRNOT00000023965

MGI ID MGI:97011
97011

RGD ID 621320

Unigene ID Hs.297413
Mm.4406
Rn.10209

Homologene ID 3659

IPI ID IPI00027509
IPI00196591
IPI00319200
IPI00330733
IPI00751342