Protein MAP2K7

URN urn:agi-llid:5609
Total Entities 0
Connectivity 846
Name MAP2K7
Description mitogen-activated protein kinase kinase 7
Notes The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically activates MAPK8/JNK1 and MAPK9/JNK2, and this kinase itself is phosphorylated and activated by MAP kinase kinase kinases including MAP3K1/MEKK1, MAP3K2/MEKK2,MAP3K3/MEKK5, and MAP4K2/GCK. This kinase is involved in the signal transduction mediating the cell responses to proinflammatory cytokines, and environmental stresses. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
Primary Cell Localization Cytoplasm
Class Protein kinase

Pathway Osteoarthritis
Skin Aging
Thrombopoietin Receptors Signaling in Platelet Maturation
Toll-like Receptors Act through MYD88-TIRAP Signaling
TLR4 Signaling in Leukocytes
T-Cell Dependent B-Cell Activation
T-Cell Independent B-Cell Activation
Peripheral T-Cell Tolerance
Th1-Cell Differentiation
Treg-Cell Differentiation
Th2-Cell Differentiation
T-Cell Receptor Signaling
Plasmin Effects in Inflammation
MC1R in anti-Inflammatory Signaling
Basophil Activation
Mast-Cell Activation via IgE Signaling
Mast-Cells De Novo Synthesized Mediators via IgE Independent Signaling
Neutrophil Recruitment and Priming
Nociception Expression Targets Signaling
ADRA1A -> IL6 Production
CNR1/2 -> IL1B/2/4/6/10 Production
DRD2 Expression Targets
PTGER2/3 -> Inflammation-Related Expression Targets
Circadian Clock Genes in Suprachiasmatic Nuclei Neurons
Apoptosis
Th1-Cells Activation and Proliferation in Atherosclerosis
Inflammatory Reaction in Acne Vulgaris
Atopic Dermatitis Onset
Mast-Cells Activation in Atopic Dermatitis
IL17 Signaling in Psoriasis
Th0-Cell Aberrant Activation in Systemic Lupus Erythematosus
B-Cell Activation in Systemic Lupus Erythematosus
Th2-Cell Function in Systemic Lupus Erythematosus
Acute Cytotoxic CD8+T-Cell Response against Melanocytes
Vitiligo
T-Cell Cytotoxic Response against Melanocytes in Vitiligo
Apoptosis of Melanocyte in Vitiligo
Humoral Immunity in Vitiligo
Treg-Cell Function in Diabetes Mellitus Type 1
Natural Killer T-Cell Roles in Diabetes Mellitus Type 1
non-Suppressive Treg-Cell in Diabetes Mellitus Type 1
TLR2 Signaling in Treg-Cell in Type 1 Diabetes (Animal Model)
Treg-Cell Activation in Diabetes Mellitus
beta-Cell Destruction through Cytokines in Diabetes Mellitus
Apoptosis of Thyroid Cell in Hashimoto's Thyroiditis
GNRH Signaling Impairment in Hypogonadotrophic Hypogonadism
CD4+T-Cell Response in Celiac Disease
OipA Signaling in Helicobacter Pylori Infection
Th2-Cell Function in Ulcerative Colitis
T-Cell Cytotoxic Response in Ulcerative Colitis
Osteoclast Activation in Multiple Myeloma
SERPINA1 Associated Liver Damage
Pancreatic Ductal Carcinoma
Pancreatic Neuroendocrine Tumors
TGFBR Signaling in Pancreatic Neoplasms
IgE Induces Airway Smooth Muscle Cell Proliferation
Basophil Activation in Asthma
Mast-Cell Activation in Asthma
Th2-Cell Response in Asthma
Mucin Production in Goblet Airway Epithelial Cells
Osteoclast Activation in Gout
TNF and IL1B Induce Metalloproteinase Synthesis in Osteoarthritis
Apoptosis of Chondrocyte
Dendritic Cell Dysfunction in Psoriatic Arthritis
Synovial Fibroblast Activation in Psoriatic Arthritis
Keratinocyte Activation in Psoriatic Arthritis
PTPN22 Role in Rheumatoid Arthritis
Osteoclast Activation in Rheumatoid Arthritis
Synovial Fibroblast Activation by Citokines in Rheumatoid Arthritis
Apoptosis Block in Synovial Fibroblast
FAS Mediated Apoptosis in Systemic Scleroderma
B-Cells Function in Systemic Scleroderma
Th2-Cells Function in Systemic Scleroderma
Skin Fibrosis
CCR5 Signaling in Macrophages
CD4+ T-Cell Function Decline in HIV
Apoptosis Block in Infected Cells
CD4+ T-Cell Death in HIV
TNF Receptor Associated Periodic Syndrome
ER Stress in Huntington Disease
Osteoclast Activation in Postmenopause
Glioma Invasion Signaling
Growth Factor Signaling in Neuroblastoma
Neuroblastoma
WNT Signaling in Breast Cancer
Angiogenesis in Endometriosis
Subepithelial Fibroblasts in Middle Ear Cholesteatoma
HPV E5 Regulates EDNRA and EGFR Signaling Pathway in Keratinocytes
ER Stress in Macular Degeneration
MYOC Associated Glaucoma
Immune System Role in Otitis Media
Alveolar Macrophage Negative Regulation Declined in COPD
Alveolar Macrophages Dysfunction in COPD
T-Cell Cytotoxic Activation
Mucin Hyperproduction in Goblet and Mucous Cells
WNT Signaling in Cystic Kidney Disease
Plasmin Role in Glomerulonephritis
Podocyte Dysfunction in Glomerulonephritis
CD38/CD19 -> JUN/FOS/NF-kB Signaling in B-cell Proliferation
ANGPT2 -> AP-1/CREBBP/MYC Expression Targets
AREG -> AP-1 Expression Targets
Dopamine/Gi Expression Targets
BTC -> AP-1/ATF/CREB Expression Targets
Frizzled Receptors -> ARRB1/ARRB2 non-Canonical Signaling
Complement Component GPCRs Signaling
EGF -> AP-1/ATF Expression Targets
EGF -> CREB/CREBBP/ELK/SRF/MYC Expression Targets
EGF -> TP53 Expression Targets
EGFR/ERBB2 -> TP53 Signaling
EGFR -> AP-1/ATF2 Signaling
EGFR -> AP-1/CREB/ELK/SRF/MYC Signaling
EREG -> AP-1/ATF Expression Targets
Erythropoietin -> AP-1/MYC/CREB Expression Targets
F2 -> AP-1/CREB/ELK/SRF/SP1 Expression Targets
PLG -> AP-1/CREB/ELK/SRF/SP1 Expression Targets
FGF9 -> AP-1/CREB/MYC Expression Targets
FGF10 -> AP-1/CREB/CREBBP/MYC Expression Targets
FGF1 -> AP-1/CREB/ELK/SRF/MYC Expression Targets
FGF8 -> AP-1/CREB/MYC Expression Targets
FGF18 -> AP-1/CREB Expression Targets
FGF4 -> AP-1/MYC Expression Targets
FGF7 -> AP-1/CREB/CREBBP/MYC Expression Targets
FGF2 -> AP-1/CREB/CREBBP/ELK/SRF/MYC Expression Targets
FGFR -> AP-1/CREB/CREBBP/ELK/SRF/MYC Signaling
FrizzledR -> JUN/PAX2 Signaling
HBEGF -> AP-1/ATF Expression Targets
HBEGF -> TP53 Expression Targets
HBEGF -> CREB/MYC Expression Targets
HGF -> AP-1/CREB/ELK/SRF/MYC Expression Targets
HGFR -> AP-1/CREB/MYC Signaling
RAS/RAF/MAPK Signaling Activation in Cancer
RAS/RAF/MAPK Signaling Activation by Blocking of Tumor Suppressors
Apoptosis Block by Death Receptor Signaling in Cancer
Apoptosis Evasion in Cancer: Overview
VEGFA Dependent Angiogenesis in Cancer
VEGF Independent Angiogenesis in Cancer
Effector T-cell Inactivation in Cancer Immune Escape
FibronectinR -> AP-1/ELK/SRF/SREBF Signaling
CTGF -> AP-1/CREB/MYC Expression Targets
PAF/Gq -> AP-1/ATF1/CREB/ERK/SRF Expression Targets
Dronabinol/Anandamide Expression Targets
S1P Expression Targets
NRG1 -> CREB/CREBBP/ELK/SRF/MYC Expression Targets
NRG1 -> TP53 Expression Target
NRG1 -> AP-1/ATF Expression Targets
NGF -> SMAD3/NF-kB Expression Targets
NGF -> AP-1/TP53/MYC Expression Targets
BDNF Expression Targets
NTF3 Expression Targets
NTF4 Expression Targets
NOTCH -> TCF3 Signaling
NOTCH Expression Targets
PDGFB -> AP-1/CREB/MYC Expression Target
PDGFD -> AP-1 Expression Targets
PDGF -> AP-1/CREB/CREBBP/MYC Expression Targets
PDGFR -> AP-1/MYC Signaling
AVP/Gs -> CREB/ELK/SRF/AP-1/EGR Expression Targets
GNRH1 Expression Targets
GNRH2 Expression Targets
EDN1 Expression Targets
EDN3 Expression Targets
AVP/Gq -> CREB/ELK/SRF/AP-1/EGR Expression Targets
AngiopoietinR -> AP-1 Signaling
GDNF -> HSF1 Signaling
EphrinB -> MAPK/JUN/FOS Signaling
NTRK -> AP-1/CREB/ELK/SRF/MYC/SMAD3/TP53 Signaling
GAS6 -> AP-1/CREB Expression Targets
FIGF -> AP-1 Expression Target
KITLG -> AP-1/CREB/CREBBP/MYC Expression Targets
GDNF -> HSF1 Expression Targets
CSF1 -> AP-1/CREB/CREBBP/MYC Expression Targets
PGF -> AP-1/CREB/CREBBP/MYC Expression Targets
FLT3LG -> AP-1/CREB/CREBBP Expression Targets
TNF-alpha/TNFRSF1A Signaling
JNK/MAPK Signaling
VEGF Signaling
EGFR Signaling
WNT Planar Cell Polarity (PCP) non-Canonical Signaling
T-Cell Receptor -> AP-1 Signaling
TGFA -> TP53 Expression Targets
TGFA/AP-1/ATF Expression Targets
TGFA -> CREB/CREBBP/ELK-SRF/MYC Expression Targets
FASLG Expression Targets
TNFSF10 Expression Targets
LTA Expression Targets
TNFSF14 Expression Targets
TNF -> AP-1 Expression Targets
CD72 -> AP-1 Expression Targets
CD40LG -> NF-kB/ELK/SRF -> CREB/NFATC Expression Targets
TNFSF13 Expression Targets
TNFSF13B Expression Targets
TNF -> ELK-SRF Expression Targets
TNF -> TP53/ATF Expression Targets
EDA Expression Targets
EctodysplasinR -> AP-1 Signaling
TNFR -> CREB/ELK-SRF Signaling
TNFR -> AP-1/ATF/TP53 Signaling
NGFR -> AP-1/CEBPB/CREB/ELK/SRF/TP53 Signaling
TNFRSF6 -> DDIT3 Signaling
TNFRSF6 -> HSF1 Signaling
TNFRSF1A -> AP-1/ATF/TP53 Signaling
TNFRSF1A -> CREB/ELK-SRF Signaling
Thrombopoietin -> SPI1 Expression Targets
Thrombopoietin -> AP-1/CREB/CREBBP/MYC Expression Targets
IL1B -> PGE2 Expression Targets
ROS in Angiotensin Mediated Cardiovascular Remodeling and Hypertrophy
VEGFA -> AP-1/CREBBP/MYC Expression Targets
VEGFR -> AP-1/CREB/MYC Signaling
WNT1 Expression Targets
WNT3A Expression Targets
WNT4 Expression Targets
WNT5A Expression Targets
WNT7A Expression Targets
1_Inflammation in keratinocytes in the pathology of acne
2_Acute phase initiation in atopic dermatitis
2_Interleukin-17 and interleukin-22 signaling in psoriasis
1_The onset of atopic dermatitis
1_TNF and IL1B provoke ECM degradation in osteoarthritis
1_Osteoclast-mediated bone resorption in postmenopausal women
2_Chondrocyte death in osteoarthritis
1_Formation of cysts in polycystic kidney disease
3_Mesangial cell dysfunction in glomerulonephritis
2_Podocyte dysfunction in glomerulonephritis
1_Disruption of luteinizing hormone and follicle-stimulating hormone secretion in PCOS
2_MYOC-associated glaucoma
3_Endoplasmic reticulum stress in age-related macular degeneration
2_Cigarette smoke and inflammation cause alveolar epithelial cell death in COPD
3_Role of alveolar macrophages in pulmonary tissue destruction in COPD
2_Lipotoxicity in NAFLD
2_HIV - induced depletion of CD4+ T-cells
4_3_Insulin resistance: FFA-related insulin resistance
2_SERPINA1-associated liver damage
mapk1 protein modificators
Interleukin-17 and interleukin-22 signaling in psoriasis

MedScan ID 5609

LocusLink ID 5609
26400
363855

Alias JNKK2
MAPK kinase 7
Dual specificity mitogen-activated protein kinase kinase 7
5930412N11
c-Jun N-terminal kinase kinase II
JNK kinase 2
stress-activated protein kinase kinase-4 SKK4
ERK kinase VII
MAP kinase kinase VII
MAPK/ERK kinase VII
Map2k7
JNK kinase II
mitogen-activated protein kinase kinase VII
OTTMUSP00000045502
OTTMUSP00000017733
MEK 7
OTTMUSP00000022436
OTTMUSP00000017734
protein kinase, mitogen-activated, kinase VII
stress-activated protein kinase kinase 4
c-Jun N-terminal kinase kinase 2
MAP kinase kinase 7
PRKMK7
MAPK/ERK kinase 7
MKK7/JNKK2/SKK4
MKK7
LOC199677
mitogen activated protein kinase kinase 7
SAPKK4
protein kinase, mitogen activated, kinase 7
MAPK kinase VII
JNK activating kinase II
Dual specificity mitogen-activated protein kinase kinase VII
5930412N11Rik
OTTMUSP00000017732
OTTMUSP00000022434
OTTHUMP00000174397
JNK activating kinase 2
ERK kinase 7
Sek2
SKK4/MKK7
MKK7a
OTTMUSP00000022437
MAPKK7
OTTMUSP00000022435
SAPK kinase 4
MEK
SAPKK-4
JNK-activating kinase 2
Mek7
JNKK 2
MAPKK 7
JNKK
SKK4
2
map2k7 {ECO:0000312|EMBL:AAX61178.1}
mitogen-activated protein kinase kinase 7
JNK activating kinase 2
JNK kinase II
JNK activating kinase II
JNK kinase 2
protein kinase, mitogen-activated, kinase 7
MAPKK7s
PRKMK7s

EC Number 2.7.12.2

GO ID 0005524
0008545
0004708
0019899
0000287
0019901
0019903
0004674
0004713
0038095
0007254
0007257
0000187
0032147
0006915
0018108
0070374
0051973
1904355
0032212
0045893
0009411
0009408
0006970
0034612
0007165
0023014
0051403
0031098
0005737
0005829
0005634
0031435
0008022
0043525
0001934
0006468
2000671
0009611
0072709
0004702
0035897
0016301
0046872
0000166
0004672
0016740
0016310
0006950
0007346
0005622
0002755
0002756
0035666
0045087
0009405
0034166
0034134
0034138
0034142
0034146
0034162
0038123
0038124
0002224
0016772
0008063
0034130
0005515

KEGG ID hsa:5609
mmu:26400
rno:363855

CellType cells in endometrial stroma
glandular cells
trophoblastic cells
germinal center cells
squamous epithelial cells
cells in seminiferus ducts
non-germinal center cells
glial cells
epidermal cells
Leydig Cells
respiratory epithelial cells
neuronal cells
cells in glomeruli
myocytes
follicle cells
cells in tubules
ovarian stroma cells
lymphoid tissue
exocrine glandular cells
hematopoietic cells
urothelial cells
smooth muscle cells
islets of Langerhans
bile duct cells
cells in red pulp
Hepatocytes
decidual cells
Macrophages
cells in granular layer
Pneumocytes
cells in molecular layer
Purkinje Cells
cells in white pulp

Tissue uterus, pre-menopause
stomach, lower
Placenta
stomach, upper
Prostate
lymph node
vagina
testis
rectum
hippocampus
vulva/anal skin
Salivary gland
nasopharynx
cerebral cortex
thyroid gland
seminal vesicle
oral mucosa
Kidney
cervix, uterine
Adrenal gland
tonsil
skeletal muscle
Ovary
Appendix
Skin
lateral ventricle
colon
small intestine
Pancreas
duodenum
bone marrow
urinary bladder
smooth muscle
Liver
epididymis
breast
spleen
parathyroid gland
esophagus
bronchus
Lung
fallopian tube
Cerebellum
gall bladder
heart muscle
uterus, post-menopause

Organism Homo sapiens {Organism urn:agi-taxid:9606}
Mus musculus {Organism urn:agi-taxid:10090}
Rattus norvegicus {Organism urn:agi-taxid:10116}
Homo sapiens
Mus musculus
Rattus norvegicus

Mouse chromosome position 8
8 A1.1

OMIM ID 603014

Rat chromosome position 12p12

Hugo ID 6847
HGNC:6847

Human chromosome position 19p13.2
19p13.3-p13.2

Swiss-Prot Accession B4DV95
O14733
O14733.2
Q8CE90
Q8CE90.1
Q4KSH7
D3XAM6
Q4KSH7.1
B2R9S5
D6W659
O14648
O14816
O60452
O60453
Q1PG43
Q8IY10
O35406
O35720
O35871
O35872
O54780
O70242
O70243
Q8BSP1
Q9QWG6
Q9R1Z3
Q9R1Z4
Q9R1Z5
Q9R1Z6
MP2K7_HUMAN
MP2K7_MOUSE
MP2K7_RAT
B2R9S5_HUMAN

GenBank ID NC_000019
XM_006722800
XP_006722863
NM_001297555
NP_001284484
NM_001297556
NP_001284485
NM_145185
NP_660186
NG_029438
AC010336
CH471139
EAW68962
EAW68963
EAW68964
EAW68965
EAW68966
EAW68967
EAW68968
AF003199
AAB63374
AF006689
AAB97813
AF013588
AAC16272
AF013589
AAC16273
AF014401
AAB88048
AF022805
AAC26142
AK098807
AK300988
BAG62607
AK313899
BAG36622
BC005365
BC038295
AAH38295
BF445461
DQ445915
ABE03013
HY063492
HY099294
O14733
NC_000074
NM_001164172
NP_001157644
NM_001042557
NP_001036022
NM_011944
NP_036074
NM_001291777
NP_001278706
NM_001291783
NP_001278712
NM_001291778
NP_001278707
AC123029
CH466566
EDL21977
EDL21978
EDL21979
EDL21980
EDL21981
EDL21982
EDL21983
U93031
AAB63448
AB005654
BAA24383
AF022112
AAC16274
AF022113
AAC16275
AF060943
AAD15819
AF060944
AAD15820
AF060945
AAD15821
AF060946
AAD15822
AF060947
AAD15823
AK031137
BAC27272
AK165184
BAE38066
AK181654
AK181910
AK196139
AK202520
AK206802
AK211581
AK213976
AK214564
AK218534
AK218599
AK219049
BB842920
BC070467
AAH70467
CO044477
U74463
AAC53364
U74464
AAC53365
U93030
AAB63447
Q8CE90
NC_005111
XM_006248769
XP_006248831
XM_008768985
XP_008767207
XM_006248768
XP_006248830
NM_001025425
NP_001020596
AC_000080
AABR07034979
AAHX01070760
CH474084
EDL74986
EDL74987
EDL74988
EDL74989
EDL74990
EDL74991
EDL74992
AY879265
AAX61178
GU264001
ADC53401
Q4KSH7
NC_018930
AMYH02035411
DQ891274
ABM82200
DQ894462
ABM85388
AC_000030
AAHY01067537
XM_005272489
XP_005272546
XM_005272490
XP_005272547
AC_000151
ABBA01010877
ABBA01010878
XM_006508805
XP_006508868
AK049267
NT_077812
NW_001838480
NW_927173
AC_000062
CR604614
NT_039455
NW_001030882
AF026216
AAB81848
AK028772
BAC26111
NW_001084669
NW_047365
AABR06069894

Swiss-Prot ID MP2K7_HUMAN
MP2K7_MOUSE
MP2K7_RAT
B2R9S5_HUMAN

Cell Localization Nucleus
Cytoplasm

Ensembl ID ENSG00000076984
ENSP00000381070.2
ENST00000397983.7
ENSP00000381068.3
ENST00000397981.7
ENSP00000381066.3
ENST00000397979.3
ENSMUSG00000002948
ENSMUSP00000003027.7
ENSMUST00000003027.13
ENSMUSP00000054512.4
ENSMUST00000062686.10
ENSMUSP00000106627.1
ENSMUST00000110999.7
ENSMUSP00000106623.1
ENSMUST00000110995.7
ENSMUSP00000106622.1
ENSMUST00000110994.8
ENSMUSP00000106626.2
ENSMUST00000110998.8
ENSRNOG00000001047
ENSRNOP00000058535.3
ENSRNOT00000061821.3
ENSRNOP00000072160.1
ENSRNOT00000084460.1
ENSP00000381070
ENST00000397983
ENSP00000381068
ENST00000397981
ENSP00000381066
ENST00000397979
ENSMUSG00000109061
ENSMUSP00000003027
ENSMUST00000003027
ENSMUSP00000054512
ENSMUST00000062686
ENSMUSP00000106627
ENSMUST00000110999
ENSMUSP00000106623
ENSMUST00000110995
ENSMUSP00000106622
ENSMUST00000110994
ENSMUSP00000106626
ENSMUST00000110998
ENSRNOP00000058535
ENSRNOT00000061821
ENSRNOP00000072160
ENSRNOT00000084460

MGI ID MGI:1346871
1346871

RGD ID 1560043

Unigene ID Hs.531754
Mm.3906
Rn.162081

Homologene ID 56548

Shape Sickle-vertex

IPI ID IPI00023636
IPI00302112
IPI00745806
IPI00794495
IPI00779757
IPI00117840
IPI00228989
IPI00280475
IPI00749972
IPI00816840
IPI00816864
IPI00816890
IPI00816911
IPI00747921
IPI00641984
IPI00639798
IPI00189128

Ensembl Transcript ID ENST00000397979

ENSEMBL ENSG00000076984

ProteinAtlas SubcellularLocation Main location: ; Other location: ; Expression type: Staining; Reliability: Uncertain

Ensembl Gene ID ENSG00000076984

ProteinAtlas NormalTissue Tissue: vulva/anal skin; Cell type: epidermal cells; Level: Moderate; Expression type: Staining; Reliability: Supportive
Tissue: pancreas; Cell type: islets of Langerhans; Level: Weak; Expression type: Staining; Reliability: Supportive
Tissue: pancreas; Cell type: exocrine glandular cells; Level: Moderate; Expression type: Staining; Reliability: Supportive
Tissue: spleen; Cell type: cells in red pulp; Level: Weak; Expression type: Staining; Reliability: Supportive
Tissue: smooth muscle; Cell type: smooth muscle cells; Level: Weak; Expression type: Staining; Reliability: Supportive
Tissue: adrenal gland; Cell type: glandular cells; Level: Low; Expression type: APE; Reliability: High
Tissue: appendix; Cell type: glandular cells; Level: Medium; Expression type: APE; Reliability: High
Tissue: appendix; Cell type: lymphoid tissue; Level: Medium; Expression type: APE; Reliability: High
Tissue: bone marrow; Cell type: hematopoietic cells; Level: High; Expression type: APE; Reliability: High
Tissue: breast; Cell type: glandular cells; Level: Medium; Expression type: APE; Reliability: High
Tissue: bronchus; Cell type: respiratory epithelial cells; Level: Medium; Expression type: APE; Reliability: High
Tissue: cerebellum; Cell type: cells in granular layer; Level: Low; Expression type: APE; Reliability: High
Tissue: cerebellum; Cell type: cells in molecular layer; Level: Low; Expression type: APE; Reliability: High
Tissue: cerebellum; Cell type: Purkinje cells; Level: Low; Expression type: APE; Reliability: High
Tissue: cerebral cortex; Cell type: glial cells; Level: Medium; Expression type: APE; Reliability: High
Tissue: cerebral cortex; Cell type: neuronal cells; Level: Medium; Expression type: APE; Reliability: High
Tissue: cervix, uterine; Cell type: glandular cells; Level: Medium; Expression type: APE; Reliability: High
Tissue: cervix, uterine; Cell type: squamous epithelial cells; Level: Low; Expression type: APE; Reliability: High
Tissue: colon; Cell type: glandular cells; Level: Medium; Expression type: APE; Reliability: High
Tissue: duodenum; Cell type: glandular cells; Level: Medium; Expression type: APE; Reliability: High
Tissue: epididymis; Cell type: glandular cells; Level: Low; Expression type: APE; Reliability: High
Tissue: esophagus; Cell type: squamous epithelial cells; Level: Medium; Expression type: APE; Reliability: High
Tissue: fallopian tube; Cell type: glandular cells; Level: Medium; Expression type: APE; Reliability: High
Tissue: gall bladder; Cell type: glandular cells; Level: Medium; Expression type: APE; Reliability: High
Tissue: heart muscle; Cell type: myocytes; Level: None; Expression type: APE; Reliability: High
Tissue: hippocampus; Cell type: glial cells; Level: Low; Expression type: APE; Reliability: High
Tissue: hippocampus; Cell type: neuronal cells; Level: Low; Expression type: APE; Reliability: High
Tissue: kidney; Cell type: cells in glomeruli; Level: Medium; Expression type: APE; Reliability: High
Tissue: kidney; Cell type: cells in tubules; Level: Medium; Expression type: APE; Reliability: High
Tissue: lateral ventricle; Cell type: glial cells; Level: Low; Expression type: APE; Reliability: High
Tissue: lateral ventricle; Cell type: neuronal cells; Level: Low; Expression type: APE; Reliability: High
Tissue: liver; Cell type: bile duct cells; Level: Low; Expression type: APE; Reliability: High
Tissue: liver; Cell type: hepatocytes; Level: Low; Expression type: APE; Reliability: High
Tissue: lung; Cell type: macrophages; Level: Medium; Expression type: APE; Reliability: High
Tissue: lung; Cell type: pneumocytes; Level: None; Expression type: APE; Reliability: High
Tissue: lymph node; Cell type: germinal center cells; Level: Medium; Expression type: APE; Reliability: High
Tissue: lymph node; Cell type: non-germinal center cells; Level: Medium; Expression type: APE; Reliability: High
Tissue: nasopharynx; Cell type: respiratory epithelial cells; Level: Medium; Expression type: APE; Reliability: High
Tissue: oral mucosa; Cell type: squamous epithelial cells; Level: Low; Expression type: APE; Reliability: High
Tissue: ovary; Cell type: follicle cells; Level: Low; Expression type: APE; Reliability: High
Tissue: ovary; Cell type: ovarian stroma cells; Level: Low; Expression type: APE; Reliability: High
Tissue: pancreas; Cell type: exocrine glandular cells; Level: Medium; Expression type: APE; Reliability: High
Tissue: pancreas; Cell type: islets of Langerhans; Level: Low; Expression type: APE; Reliability: High
Tissue: parathyroid gland; Cell type: glandular cells; Level: Medium; Expression type: APE; Reliability: High
Tissue: placenta; Cell type: decidual cells; Level: Low; Expression type: APE; Reliability: High
Tissue: placenta; Cell type: trophoblastic cells; Level: Medium; Expression type: APE; Reliability: High
Tissue: prostate; Cell type: glandular cells; Level: Medium; Expression type: APE; Reliability: High
Tissue: rectum; Cell type: glandular cells; Level: Medium; Expression type: APE; Reliability: High
Tissue: salivary gland; Cell type: glandular cells; Level: Low; Expression type: APE; Reliability: High
Tissue: seminal vesicle; Cell type: glandular cells; Level: Medium; Expression type: APE; Reliability: High
Tissue: skeletal muscle; Cell type: myocytes; Level: None; Expression type: APE; Reliability: High
Tissue: skin; Cell type: epidermal cells; Level: Low; Expression type: APE; Reliability: High
Tissue: small intestine; Cell type: glandular cells; Level: Medium; Expression type: APE; Reliability: High
Tissue: smooth muscle; Cell type: smooth muscle cells; Level: Low; Expression type: APE; Reliability: High
Tissue: spleen; Cell type: cells in red pulp; Level: Low; Expression type: APE; Reliability: High
Tissue: spleen; Cell type: cells in white pulp; Level: Low; Expression type: APE; Reliability: High
Tissue: stomach, lower; Cell type: glandular cells; Level: Medium; Expression type: APE; Reliability: High
Tissue: stomach, upper; Cell type: glandular cells; Level: Medium; Expression type: APE; Reliability: High
Tissue: testis; Cell type: cells in seminiferus ducts; Level: High; Expression type: APE; Reliability: High
Tissue: testis; Cell type: Leydig cells; Level: Low; Expression type: APE; Reliability: High
Tissue: thyroid gland; Cell type: glandular cells; Level: Low; Expression type: APE; Reliability: High
Tissue: tonsil; Cell type: germinal center cells; Level: Medium; Expression type: APE; Reliability: High
Tissue: tonsil; Cell type: non-germinal center cells; Level: Medium; Expression type: APE; Reliability: High
Tissue: tonsil; Cell type: squamous epithelial cells; Level: Low; Expression type: APE; Reliability: High
Tissue: urinary bladder; Cell type: urothelial cells; Level: Medium; Expression type: APE; Reliability: High
Tissue: uterus, post-menopause; Cell type: cells in endometrial stroma; Level: None; Expression type: APE; Reliability: High
Tissue: uterus, post-menopause; Cell type: glandular cells; Level: Low; Expression type: APE; Reliability: High
Tissue: uterus, pre-menopause; Cell type: cells in endometrial stroma; Level: Low; Expression type: APE; Reliability: High
Tissue: uterus, pre-menopause; Cell type: glandular cells; Level: Medium; Expression type: APE; Reliability: High
Tissue: vagina; Cell type: squamous epithelial cells; Level: Medium; Expression type: APE; Reliability: High
Tissue: vulva/anal skin; Cell type: epidermal cells; Level: Medium; Expression type: APE; Reliability: High