Protein VEGFA

URN urn:agi-llid:7422
Total Entities 0
Connectivity 18176
Name VEGFA
Description vascular endothelial growth factor A
Notes This gene is a member of the PDGF/VEGF growth factor family. It encodes a heparin-binding protein, which exists as a disulfide-linked homodimer. This growth factor induces proliferation and migration of vascular endothelial cells, and is essential for both physiological and pathological angiogenesis. Disruption of this gene in mice resulted in abnormal embryonic blood vessel formation. This gene is upregulated in many known tumors and its expression is correlated with tumor stage and progression. Elevated levels of this protein are found in patients with POEMS syndrome, also known as Crow-Fukase syndrome. Allelic variants of this gene have been associated with microvascular complications of diabetes 1 (MVCD1) and atherosclerosis. Alternatively spliced transcript variants encoding different isoforms have been described. There is also evidence for alternative translation initiation from upstream non-AUG (CUG) codons resulting in additional isoforms. A recent study showed that a C-terminally extended isoform is produced by use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism, and that this isoform is antiangiogenic. Expression of some isoforms derived from the AUG start codon is regulated by a small upstream open reading frame, which is located within an internal ribosome entry site. [provided by RefSeq, Nov 2015]
Primary Cell Localization Extracellular
Class Ligand
ObjectType Protein

Pathway Osteoarthritis
Somatostatin Receptors Signaling
Eosinophil Survival by Cytokine Signaling
Eosinophil Activation
Mast-Cell Activation via IgE Signaling
Mast-Cell Activation without Degranulation through CRHR1 Signaling
Mast-Cell Activation without Degranulation
anti-Inflammatory Function of Macrophage M2 Lineage
VEGFA/NOTCH1/WNT Cross-talk in Blood Vessel Sprouting and Branching in Cancer
Vascular Endothelial Cell Activation by NO
Vascular Smooth Muscle Cell/Pericyte Migration and Proliferation
Vascular Endothelial Cell Activation by Blood Coagulation Factors
Vascular Endothelial Cell Activation by Growth Factors
Vascular Endothelial Cell Permeability Activation
Nociception Expression Targets Signaling
CCR1 Expression Targets
IL1B Expression Targets -> Nociception
Hemapoietic Stem Cell -> Lymphoid Multipotent Progenitor Surface Expression Markers
Proteins Involved in Atherosclerosis
Proteins Involved in Dilated Cardiomyopathy
Proteins Involved in Arterial Hypertension
Arterial Hypertension
Proteins Involved in Pulmonary Hypertension
Proteins Involved in Hypoxia-Induced Pulmonary Hypertension
Endothelial Cell Dysfunction in Pulmonary Hypertension
BMP2 and Canonical WNT Signaling in Pulmonary Artery Endothelial Cells
Proteins Involved in Myocardial Ischemia
Proteins Involved in Myocarditis
Proteins Involved in Androgenetic Alopecia
Proteins with Altered Expression in Melanoma
Melanoma
MITF as a Regulator of Melanoma Cell Development
Proteins Involved in Melanoma
IL17 Signaling in Psoriasis
Proteins Involved in Psoriasis
Genes with Mutations Associated with Psoriasis
Dendritic Cells Function in Psoriasis
Proteins Involved in Diabetes Mellitus Type 2
Peripheral Tissue Microangiopathy
Endothelial Cell Dysfunction in Progressive Diabetic Nephropathy
Proteins Involved in Diabetic Nephropathy
Proteins Involved in Diabetic Neuropathy
Microangiopathy in Diabetic Neuropathy
Proliferative Diabetic Retinopathy
Proteins Involved in non-Alcoholic Fatty Liver Disease
Proteins Involved in Hashimoto's Thyroiditis
Proteins Involved in Obesity
Proteins Involved in Prolactinoma
Prolactinoma Overiew
Proteins Involved in Colorectal Neoplasms
Cetuximab Resistance in Colorectal Cancer
Metastatic Colorectal Cancer
Proteins Involved in Inflammatory Bowel Diseases
CagA Phosphorylation Dependent Signaling
Proteins Involved in Ulcerative Colitis
Proteins Involved in B-Cell Chronic Lymphocytic Leukemia
Proteins Involved in Hodgkin Lymphoma
TNFR/NF-kB Classical Pathway in Multiple Myeloma Plasma Cells
Osteoclast Activation in Multiple Myeloma
IL6/IGF1/VEGFA Signaling in Multiple Myeloma
Multiple Myeloma
Proteins Involved in Multiple Myeloma
NOTCH Signaling in Multiple Myeloma
Proteins Involved in Thrombophilia
Vascularization in Hepatocellular Carcinoma
Proteins Involved in Hepatocellular Carcinoma
Hepatocellular Carcinoma
Growth Factor Signaling in Hepatocellular Carcinoma
Proteins Involved in Pancreatic Cancer
Pancreatic Ductal Carcinoma
Growth Factor Signaling in Pancreatic Neoplasms
ADAM33 Role in Asthma
Eosinophil Survival in Asthma
Mast-Cell Activation in Asthma
CFTR Facilitates Oxidative Stress in Airway Epithelium in CF
Proteins Involved in Osteoarthritis
Proteins Involved in Polycystic Ovary Syndrome
Synovial Fibroblast Activation in Psoriatic Arthritis
Keratinocyte Activation in Psoriatic Arthritis
Synovial Fibroblast Activation by Citokines in Rheumatoid Arthritis
TLR2 Induced Synovial Fibroblast Activation in Rheumatoid Arthritis
Proteins Involved in Rheumatoid Arthritis
Proteins Involved in Systemic Scleroderma
Skin Fibrosis
Estrogen Effects on Pregnancy Gingivitis
Proteins Involved in Periodontitis
Proteins with Altered Expression in Osteoarthritis
Proteins Involved in Osteoporosis
Proteins with Altered Expression in Psoriatic Arthritis
Proteins Involved in Epilepsy
Proteins Involved in Glioblastoma
Proteins Involved in Astrocytoma
Proteins Involved in Glioma
Growth Factor Signaling in Neuroblastoma
Neuroblastoma
ALK Associated Neuroblastoma
Proteins Involved in Neuroblastoma
SOD1 Mutation
Proteins with Altered Expression in Amyotrophic Lateral Sclerosis
Proteins Involved in Amyotrophic Lateral Sclerosis
Neuroinflammation in Amyotrophic Lateral Sclerosis
Proteins Involved in Multiple Sclerosis
Genes with Mutations Associated with Vascular Dementia
Proteins Involved in Vascular Dementia
Proteins Involved in Breast Cancer Related to WNT Signaling Pathway
Proteins Involved in Breast Cancer Related to NOTCH Signaling Pathway
WNT Signaling in Breast Cancer
Proteins Involved in Breast Cancer Related to ERBB2/VEGFR/Akt Signaling Pathway
ERBB/VEGFR/Akt Signaling in Breast Cancer
ESR1/ERBB Positive Luminal Breast Cancer
Proteins with Altered Expression in Breast Cancer
Breast Cancer
NOTCH1 Signaling in Breast Cancer
Endometrial Cancer
Proteins Involved in Endometrial Cancer
Proteins with Altered Expression in Endometrial Cancer
Local Estrogen Production in Endometriosis
Proteins Involved in Endometriosis
Angiogenesis in Endometriosis
Proteins with Altered Expression in Endometriosis
Coagulation Factors and PAR1/2 Receptors (F2R/F2RL1) in Endometriosis
Proteins Involved in Spontaneous Abortion
Proteins Involved in High-Grade Serous Ovarian Carcinoma
High-Grade Serous Ovarian Carcinoma
Ovarian Cancer
Proteins with Altered Expression in Ovarian Cancer
Proteins Involved in Cholesteatoma
IL6/JAK/STAT3 Signaling in Cholesteatoma
Cholesteatoma
HPV Infection and Cancer
HPV E6 and E7 Induced Disruption of TNFR/NF-kB Signaling in Keratinocytes
HPV E5 Regulates EDNRA and EGFR Signaling Pathway in Keratinocytes
Kruppel-like Factor 6 Signaling in Prostate Cancer
Androgen Receptor/Beta-2-Microglobulin Signaling in Prostate Cancer
Prostate Cancer
Proteins Involved in Prostate Cancer
Netrin-1 Signaling in Age-Related Macular Degeneration
Oxidative Stress, All-Trans-Retinal and Lipofuscin Toxicity in AMD
Proteins Involved in Age-Related Macular Degeneration
IL10/STAT3 Signaling in M2 Macrophage and Retinal Angiogenesis
ER Stress in Macular Degeneration
Genes with Mutations Associated with Age-Related Macular Degeneration
Proteins Involved in Cataract
HIF1A in Pathologic Ocular Neovascularization
VEGFA in Neovascular Glaucoma
Proteins with Altered Expression in Glaucoma
Proteins Involved in Noise-Induced Hearing Loss
Proteins with Altered Expression in Chronic Obstructive Pulmonary Disease
Proteins Involved in Chronic Obstructive Pulmonary Disease
VEGFA Low Expression Level in Chronic Bronchitis
VEGFA High Expression Level in Pulmonary Emphysema
Proteins Involved in Pulmonary Emphysema
Proteins Involved in Chronic Bronchitis
Proteins Involved in Erectile Dysfunction
Proteins Involved in Glomerulonephritis
Endothelial Cell Dysfunction in Glomerulonephritis
Podocyte Dysfunction in Glomerulonephritis
HMGB1 Expression Targets
S100B Expression Targets
Noradrenaline/Gs Expression Targets
Serotonin/Gs Expression Targets
Noreadrenaline/Gq Expression Targets
Acetylcholine Expression Targets
Serotonin/Gq Expression Targets
BMP6/ACVR2A Expression Targets
BMP2/BMPR2 Expression Targets
BMP7/ACVR2 Expression Targets
BMP4/BMPR2 Expression Targets
BMP7/BMPR2/ACVR2 Expression Targets
Elevated Receptors -> Expression Targets in Joint
Receptor Tyrosine Kinase Family -> Expression Targets in Bone
Elevated Receptors -> Expression Targets in Bone and Joint
Elevated Receptors -> Expression Targets in Bone
CD8 -> ATF/CREB/CREBBP Expression Targets
CTF1 Expression Targets
Elevated Receptors -> Expression Targets in Blood vessel
Elevated Receptors -> Expression Targets in Aorta
Elevated Receptors -> Expression Targets in Blood Vessel
CXCL1 Expression Targets
CXCL2 Expression Targets
CXCL12 Expression Targets
CCL3 Expression Targets
CCL3L1 Expression Target
CSF2 -> NF-kB Expression Targets
CSF2 -> STAT Expression Targets
LIF Expression Targets
EGF -> CTNN Expression Targets
EGF -> HIF1A Expression Targets
EGF -> AP-1/ATF Expression Targets
EGF -> CREB/CREBBP/ELK/SRF/MYC Expression Targets
EGF -> MEF/MYOD/NFATC Expression Targets
EGF -> STAT Expression Targets
Erythropoietin -> NF-kB Expression Targets
Erythropoietin -> AP-1/MYC/CREB Expression Targets
Erythropoietin -> STAT Expression Targets
Erythropoietin -> ELK/SRF Expression Targets
F2 -> AP-1/CREB/ELK/SRF/SP1 Expression Targets
F2 -> STAT1/NF-kB Expression Targets
PLG -> STAT1/NF-kB Expression Targets
FGF9 -> AP-1/CREB/MYC Expression Targets
FGF2 -> STAT Expression Targets
FGF1 -> AP-1/CREB/ELK/SRF/MYC Expression Targets
FGF7 -> RUNX Expression Targets
FGF1 -> STAT Expression Targets
FGF9 -> STAT Expression Targets
FGF9 -> RUNX Expression Targets
FGF7 -> AP-1/CREB/CREBBP/MYC Expression Targets
FGF2 -> AP-1/CREB/CREBBP/ELK/SRF/MYC Expression Targets
GCG Expression Targets
ADCYAP1 Expression Targets
FSHR Expression Targets
VIP Expression Targets
GH1/GHR -> NF-kB/ELK/SRF/MYC Expression Targets
GH1/GHR -> STAT Expression Targets
GH1/PRLR Expression Targets
HBEGF -> STAT Expression Targets
HBEGF -> AP-1/ATF Expression Targets
HBEGF -> EP300/ETS/ETV/SP1 Expression Targets
HBEGF -> HIF1A Expression Targets
HBEGF -> MEF/MYOD Expression Target
HBEGF -> CREB/MYC Expression Targets
HGF -> STAT Expression Targets
HGF -> AP-1/CREB/ELK/SRF/MYC Expression Targets
STAT3 and NFkB Activate Inflammation-Induced Tumorigenesis
IL23A and IL17A Provoke Cancer-Associated Inflammation
STAT3 Inhibits Maturation of Dendritic Cells and Facilitates Cancer Progression
Proteins with Altered Expression in Tumor-Promoting Inflammation
N2 Neutrophils in Tumor-Promoting Inflammation and Tumor Progression
Oxidized LDL/OLR1 Activates Cell Proliferation in Cancer
HIF1A in Vasculogenic Mimicry of Cancer
VEGFA Dependent Angiogenesis in Cancer
ANGPT/TEK Maintains Endothelial Cell Quiescence in Cancer
ANGPT/TEK Stimulates Endothelial Cell Migration in Cancer
Inhibition of THBS1 Activates Angiogenesis in Cancer
FBLN5 Potentiates Migration and Proliferation of Endothelial Cells in Cancer
HIF1A as Master Regulator of Angiogenesis in Cancer
Proteins with Altered Expression in Cancer Metastases
BSG (CD147) in Cancer Cells Motility, Invasion and Survival
Lactate as a Signaling Molecule in Cancer Cells
Proteins with Altered Expression in Cancer Metabolic Reprogramming
Tumor Infiltrating Macrophages in Cancer Progression and Immune Escape
IGF1 -> MEF/MYOD/MYOG Expression Targets
IGF1 -> CEBPA/FOXO1A Expression Targets
IGF2 -> STAT Expression Targets
IGF1 -> STAT Expression Targets
IGF2 -> CEBPA/FOXO1A Expression Targets
IGF2/MEF/MYOD Expression Targets
IGF2 -> HIF1A/MYC Expression Targets
IGF1 -> ELK/SRF/HIF1A/MYC/SREBF Expression Targets
INHBA/ACVR2/BMPR Expression Targets
INHBA/ACVR2/ACVR1 Expression Targets
Insulin -> STAT Expression Targets
Insulin -> CEBPA/CTNNB/FOXA/FOXO Expression Targets
Insulin -> MEF/MYOD Expression Targets
Insulin -> ELK/SRF/HIF1A/MYC/SREBF Expression Targets
CTGF -> AP-1/CREB/MYC Expression Targets
Fibrinogen Expression Targets
EGFR -> Expression Targets in Skin
Elevated Receptors -> Expression Targets in Skin
IFNA1/IFNR Expression Targets
IFNG/IFNR Expression Targets
IL13 Expression Targets
IL3 Expression Targets
IL6 Expression Targets
IL11 Expression Targets
Leptin -> STAT Expression Targets
Leptin -> ELK/SRF Expression Targets
Prostaglandin F Expression Targets
LPA Expression Targets
PAF/Gq -> AP-1/ATF1/CREB/ERK/SRF Expression Targets
Morphine Expression Targets
S1P Expression Targets
PGE1 Expression Targets
Elevated Receptors -> Expression Targets in Lymphoid System and Blood
GPCRs Family -> Expression Targets in Lymphoid System and Blood
Receptor Tyrosine Kinase Family -> Expression Targets in Lymphoid System and Blood
CD40 -> Expression Targets in Lymph Node
NRG1 -> MEF/MYOD Expression Targets
NRG1 -> EP300/ETS/ETV/SP1 Expression Targets
NRG1 -> CREB/CREBBP/ELK/SRF/MYC Expression Targets
NRG1/Catenin Expression Targets
NRG1 -> STAT Expression Targets
NRG1 -> AP-1/ATF Expression Targets
NRG1 -> HIF1A Expression Target
PTGER4 -> Expression Targets in Nerve Tissue
NTRK2 -> Expression Targets in Brain
NGF -> SMAD3/NF-kB Expression Targets
NGF -> AP-1/TP53/MYC Expression Targets
BDNF Expression Targets
ADAM17 Expression Targets
Adenosine Expression Targets
OSM/OSMR Expression Targets
PDGFB -> AP-1/CREB/MYC Expression Target
PDGFD -> AP-1 Expression Targets
PDGF -> AP-1/CREB/CREBBP/MYC Expression Targets
PDGF -> STAT Expression Targets
PDGFB -> STAT Expression Target
POMC Expression Targets
EDN1 Expression Targets
AGT -> CREB Expression Targets
AGT -> STAT Expression Targets
PRL/PRLR Expression Targets
PRL/GHR -> STAT Expression Targets
PRL/GHR -> NF/kB/ELK/SRF/MYC Expression Targets
CSF1 -> STAT Expression Targets
KITLG -> STAT Expression Targets
KITLG -> AP-1/CREB/CREBBP/MYC Expression Targets
EFNA1 -> STAT Expression Target
PAF Expression Targets
CSF1 -> AP-1/CREB/CREBBP/MYC Expression Targets
PGF -> AP-1/CREB/CREBBP/MYC Expression Targets
GDF5/BMPR2/ACVR2 Expression Targets
Elevated Receptors -> Expression Targets in Uterus
Elevated Receptors -> Expression Targets in Ear
HIF1 Signaling
Ras-GAP Regulation Signaling
VEGF Signaling
TGFA -> STAT Expression Targets
TGFA -> CTNNB/CTNND Expression Targets
TGFA -> HIF1A Expression Targets
TGFA -> MEF/MYOD/NFATC Expression Targets
TGFA/AP-1/ATF Expression Targets
TGFA -> CREB/CREBBP/ELK-SRF/MYC Expression Targets
TGFB2-TGFBR1 Expression Targets
TGFB3-TGFBR1 Expression Targets
TGFB1-TGFBR1 Expression Targets
TGFB3-TGFBR2 Expression Targets
TGFB2-TGFBR2 Expression Targets
TGFB1-TGFBR2 Expression Targets
TGFB1-TGFBR1/AP-1 Expression Targets
TGFB1-ACVRL1 Expression Targets
TNF -> NF-kB Expression Targets
TNF -> AP-1 Expression Targets
CD72 -> AP-1 Expression Targets
CD40LG -> STAT Expression Targets
CD40LG -> NF-kB/ELK/SRF -> CREB/NFATC Expression Targets
TNF -> STAT Expression Targets
Thrombopoietin -> AP-1/CREB/CREBBP/MYC Expression Targets
Thrombopoietin -> STAT Expression Targets
Thrombopoietin -> SP1 Expression Targets
TLR3 Expression Targets
TLR4 -> AP-1 Expression Targets
IL1B -> NO Expression Targets
IL1B -> PGE2 Expression Targets
TLR1 -> 2/6 Expression Targets
IL1B Expression Targets
TLR4 -> NF-kB/IRF Expression Targets
IL1A Expression Targets
ROS in Triggering Vascular Inflammation
VEGFA -> ATF/CREB/ELK-SRF Expression Targets
VEGFA -> NFATC Expression Targets
VEGFA -> STAT Expression Targets
VEGFA -> FOXO3A Expression Targets
VEGFA -> AP-1/CREBBP/MYC Expression Targets
VEGFA -> CTNNB/CTNND Expression Targets
VEGFA -> NCOR2 Expression Target
VEGFR -> CTNND Signaling
VEGFR -> CTNNB Signaling
VEGFR -> NFATC Signaling
VEGFR -> STAT Signaling
VEGFR -> AP-1/CREB/MYC Signaling
VEGFR -> FOXO3A Signaling
VEGFR -> ATF/CREB/ELK-SRF Signaling
WNT1 Expression Targets
WNT3A Expression Targets
WNT Canonical Signaling Expression Targets
pprarg neg, uknown targets, ps-positive
prarg neg,ukn expres targets, ps-positive
PPARG negative targets
pparg expr target_regulators
Neighbors of disease exacerbation
Neighbors of tumor progression
Neighbors of cancer progression
Neighbors of inflammatory status
Neighbors of overall survival
Neighbors of disease severity
Neighbors of tumor size
Neighbors of lesion size
Neighbors of mortality
Neighbors of survival rate
Neighbors of infarct size
Neighbors of survival time
Neighbors of functional recovery
Neighbors of insulin sensitivity
Neighbors of bacterial load
Neighbors of cancer survival
Neighbors of graft survival
Neighbors of therapeutic efficacy
Neighbors of clinical stage
Neighbors of lethality
Neighbors of tumor regression
Neighbors of recurrence-free survival
Neighbors of disease-free survival
Neighbors of tumor response
Neighbors of macrophage count
Neighbors of long-term survival
Neighbors of treatment outcome
Neighbors of bone mass
Neighbors of body weight
Neighbors of body weight gain
Neighbors of cardiovascular risk
Neighbors of microvessel density
Neighbors of tumor recurrence
Neighbors of tumor promotion
Neighbors of glucose tolerance
Neighbors of morbidity
Neighbors of fibrosis progression
Neighbors of mortality rate
Neighbors of fat mass
Neighbors of exhaustion
Neighbors of bone mineral density
Neighbors of adverse outcome
Neighbors of radioresistance
Neighbors of cell density
Neighbors of cancer-specific survival
Neighbors of progression-free survival
Neighbors of apoptosis rate
Neighbors of early mortality
Neighbors of shear stress
Neighbors of blood pressure
Neighbors of leukocyte count
Neighbors of tumor grade
Neighbors of vascular reactivity
Neighbors of vascular leakage
Neighbors of body mass index
Neighbors of vascular density
Neighbors of muscle mass
Neighbors of cancer risk
Neighbors of cancer incidence
Neighbors of tumor aggressiveness
Neighbors of systolic blood pressure
Neighbors of tumor resistance
Neighbors of blood glucose
Neighbors of ejection fraction
Neighbors of median survival
Neighbors of renal hypertrophy
Neighbors of fasting plasma glucose
Neighbors of osteoclast number
Neighbors of cancer recurrence
Neighbors of T-cell count
Neighbors of antimetastatic activity
Neighbors of energy expenditure
Neighbors of glucose level
Neighbors of vascular tone
Neighbors of radiosensitivity
Neighbors of left ventricular ejection fraction
Neighbors of breast cancer risk
Neighbors of proliferation index
Neighbors of cell permeability
Neighbors of pregnancy outcome
Neighbors of neurological outcome
Neighbors of infarct area
Neighbors of fertility
Neighbors of recurrence rate
Neighbors of pathological response
Neighbors of skin thickness
Neighbors of insulin level
Neighbors of comorbidity
Neighbors of bone volume
Neighbors of fibroblast phenotype
Neighbors of fractional shortening
Neighbors of disease exacerbation
Neighbors of tumor progression
Neighbors of cancer progression
Neighbors of inflammatory status
Neighbors of overall survival
Neighbors of disease severity
Neighbors of tumor size
Neighbors of lesion size
Neighbors of mortality
Neighbors of survival rate
Neighbors of infarct size
Neighbors of survival time
Neighbors of functional recovery
Neighbors of insulin sensitivity
Neighbors of bacterial load
Neighbors of cancer survival
Neighbors of graft survival
Neighbors of therapeutic efficacy
Neighbors of clinical stage
Neighbors of lethality
Neighbors of tumor regression
Neighbors of recurrence-free survival
Neighbors of disease-free survival
Neighbors of tumor response
Neighbors of macrophage count
Neighbors of long-term survival
Neighbors of treatment outcome
Neighbors of bone mass
Neighbors of body weight
Neighbors of body weight gain
Neighbors of cardiovascular risk
Neighbors of microvessel density
Neighbors of tumor recurrence
Neighbors of tumor promotion
Neighbors of glucose tolerance
Neighbors of morbidity
Neighbors of fibrosis progression
Neighbors of mortality rate
Neighbors of fat mass
Neighbors of exhaustion
Neighbors of bone mineral density
Neighbors of adverse outcome
Neighbors of radioresistance
Neighbors of cell density
Neighbors of cancer-specific survival
Neighbors of progression-free survival
Neighbors of apoptosis rate
Neighbors of early mortality
Neighbors of shear stress
Neighbors of blood pressure
Neighbors of leukocyte count
Neighbors of tumor grade
Neighbors of vascular reactivity
Neighbors of vascular leakage
Neighbors of body mass index
Neighbors of vascular density
Neighbors of muscle mass
Neighbors of cancer risk
Neighbors of cancer incidence
Neighbors of tumor aggressiveness
Neighbors of systolic blood pressure
Neighbors of tumor resistance
Neighbors of blood glucose
Neighbors of ejection fraction
Neighbors of median survival
Neighbors of renal hypertrophy
Neighbors of fasting plasma glucose
Neighbors of osteoclast number
Neighbors of cancer recurrence
Neighbors of T-cell count
Neighbors of antimetastatic activity
Neighbors of energy expenditure
Neighbors of glucose level
Neighbors of vascular tone
Neighbors of radiosensitivity
Neighbors of left ventricular ejection fraction
Neighbors of breast cancer risk
Neighbors of proliferation index
Neighbors of cell permeability
Neighbors of pregnancy outcome
Neighbors of neurological outcome
Neighbors of infarct area
Neighbors of fertility
Neighbors of recurrence rate
Neighbors of pathological response
Neighbors of skin thickness
Neighbors of insulin level
Neighbors of comorbidity
Neighbors of bone volume
Neighbors of fibroblast phenotype
Neighbors of fractional shortening
Neighbors of cell development
Neighbors of immune response
Neighbors of cell population
Neighbors of T-cell development
Neighbors of inflammatory response
Neighbors of wound healing
Neighbors of angiogenesis
Neighbors of innate immune response
Neighbors of cell function
Neighbors of macrophage activation
Neighbors of cell formation
Neighbors of adaptive immune response
Neighbors of osteoclast development
Neighbors of epithelial to mesenchymal transition
Neighbors of immunity
Neighbors of cell proliferative response
Neighbors of chemotaxis
Neighbors of dendritic cell differentiation
Neighbors of cell survival
Neighbors of osteoclast differentiation
Neighbors of cell phenotype
Neighbors of T-cell proliferation
Neighbors of tissue remodeling
Neighbors of cell adhesion
Neighbors of T-cell activation
Neighbors of endothelial cell proliferation
Neighbors of fibrogenesis
Neighbors of tumor growth
Neighbors of dendritic cell development
Neighbors of tissue repair
Neighbors of cell count
Neighbors of cell infiltration
Neighbors of cell interaction
Neighbors of SMC proliferation
Neighbors of lumen formation
Neighbors of endothelial cell migration
Neighbors of adipogenesis
Neighbors of lipid storage
Neighbors of cell damage
Neighbors of pregnancy
Neighbors of monocyte differentiation
Neighbors of aging
Neighbors of cell motility
Neighbors of bone resorption
Neighbors of monocyte migration
Neighbors of fibroblast proliferation
Neighbors of adipocyte differentiation
Neighbors of macrophage migration
Neighbors of microglial activation
Neighbors of neutrophil recruitment
Neighbors of regeneration
Neighbors of cell migration
Neighbors of cancer growth
Neighbors of stem cell proliferation
Neighbors of smooth muscle cell migration
Neighbors of hepatic regeneration
Neighbors of transendothelial migration
Neighbors of phagocytosis
Neighbors of immune system activation
Neighbors of leukocyte migration
Neighbors of leukocyte recruitment
Neighbors of osteoclast formation
Neighbors of monocyte recruitment
Neighbors of cell invasion
Neighbors of heart function
Neighbors of hemopoiesis
Neighbors of bone remodeling
Neighbors of ossification
Neighbors of T-cell function
Neighbors of immune system function
Neighbors of lung development
Neighbors of autophagy
Neighbors of monocyte adhesion
Neighbors of transcription activation
Neighbors of senescence
Neighbors of T-cell response
Neighbors of tumor immunity
Neighbors of hepatocyte proliferation
Neighbors of cell transdifferentiation
Neighbors of neuroprotection
Neighbors of stem cell differentiation
Neighbors of endothelial cell function
Neighbors of neuronal death
Neighbors of cell growth
Neighbors of ROS generation
Neighbors of epithelial cell proliferation
Neighbors of first trimester pregnancy
Neighbors of cancer cell growth
Neighbors of sensitization
Neighbors of hemato-encephalic barrier
Neighbors of macrophage function
Neighbors of cellular immune response
Neighbors of cellular senescence
Neighbors of colony formation
Neighbors of macrophage differentiation
Neighbors of cell differentiation
Neighbors of keratinocyte proliferation
Neighbors of stem cell migration
Neighbors of life span
Neighbors of cell homeostasis
Neighbors of psoriasis
Neighbors of inflammatory disease
Neighbors of rheumatoid arthritis
Neighbors of atherosclerosis
Neighbors of fibrosis
Neighbors of colitis
Neighbors of arthritis
Neighbors of inflammatory bowel disease
Neighbors of injury
Neighbors of atherogenesis
Neighbors of vascular remodeling
Neighbors of metastasis
Neighbors of carcinogenesis
Neighbors of multiple sclerosis
Neighbors of chronic inflammation
Neighbors of inflammation
Neighbors of tumor microenvironment
Neighbors of pathological angiogenesis
Neighbors of obesity
Neighbors of vascular disease
Neighbors of diabetes mellitus
Neighbors of asthma
Neighbors of pneumonia
Neighbors of hyperplasia
Neighbors of osteoarthritis
Neighbors of liver fibrosis
Neighbors of chronic obstructive pulmonary disease
Neighbors of myocardial infarction
Neighbors of leukocyte infiltration
Neighbors of reperfusion injury
Neighbors of airway inflammation
Neighbors of hepatitis
Neighbors of insulin resistance
Neighbors of infection
Neighbors of vascular injury
Neighbors of renal injury
Neighbors of preeclampsia
Neighbors of macrophage infiltration
Neighbors of liver injury
Neighbors of neuroinflammation
Neighbors of sepsis
Neighbors of death
Neighbors of type 1 diabetes
Neighbors of encephalomyelitis
Neighbors of autoimmune disease
Neighbors of ischemic stroke
Neighbors of dermatitis
Neighbors of neutrophil infiltration
Neighbors of heart disease
Neighbors of diabetic nephropathy
Neighbors of lung injury
Neighbors of immunopathology
Neighbors of systemic sclerosis
Neighbors of hepatocellular carcinoma
Neighbors of acute lung injury
Neighbors of gastric cancer
Neighbors of atherosclerotic plaque
Neighbors of experimental autoimmune encephalomyelitis
Neighbors of colorectal cancer
Neighbors of cardiac remodeling
Neighbors of breast cancer
Neighbors of ischemia
Neighbors of systemic lupus erythematosus
Neighbors of melanoma
Neighbors of collagen-induced arthritis
Neighbors of cartilage degeneration
Neighbors of interstitial fibrosis
Neighbors of neoplasm invasion
Neighbors of kidney disease
Neighbors of heart failure
Neighbors of lung disease
Neighbors of pulmonary fibrosis
Neighbors of cardiovascular disease
Neighbors of stroke
Neighbors of cancer
Neighbors of cerebral ischemia
Neighbors of type 2 diabetes
Neighbors of neoplasm
Neighbors of endometriosis
Neighbors of neointima
Neighbors of vasculitis
Neighbors of atrophy
Neighbors of diet-induced obesity
Neighbors of respiratory hypersensitivity
Neighbors of myocardial fibrosis
Neighbors of synovitis
Neighbors of coronary artery disease
Neighbors of rupture
Neighbors of endothelial cell dysfunction
Neighbors of liver disease
Neighbors of prostate cancer
Neighbors of hypertrophy
Neighbors of osteolysis
Neighbors of ovarian cancer
Neighbors of pancreatic cancer
Neighbors of hypertension
Neighbors of intimal hyperplasia
Neighbors of allograft rejection
Neighbors of proteinuria
Neighbors of epithelial cell
Neighbors of keratinocyte
Neighbors of vascular smooth muscle cell
Neighbors of umbilical vein endothelial cell
Neighbors of monocyte
Neighbors of endometrial stromal cell
Neighbors of alveolar macrophage
Neighbors of synoviocyte
Neighbors of macrophage
Neighbors of adipocyte
Neighbors of activated monocyte
Neighbors of fibroblast
Neighbors of airway epithelial cell
Neighbors of PBMC
Neighbors of stromal cell
Neighbors of airway smooth muscle cell
Neighbors of osteoblast
Neighbors of pneumocyte
Neighbors of endometrium cell
Neighbors of microglia
Neighbors of trophoblast
Neighbors of intestine epithelium cell
Neighbors of mononuclear cell
Neighbors of hepatic stellate cell
Neighbors of hepatocyte
Neighbors of decidual cell
Neighbors of kidney mesangial cell
Neighbors of endothelial cell
Neighbors of dendritic cell
Neighbors of Kuppfer cell
Neighbors of proadipocyte
Neighbors of kidney tubule cell
Neighbors of inflammatory cell
Neighbors of bone marrow macrophage
Neighbors of peritoneal macrophage
Neighbors of osteoclast
Neighbors of neutrophil
Neighbors of smooth muscle myocyte
Neighbors of astrocyte
Neighbors of bone marrow derived dendritic cell
Neighbors of lung fibroblast
Neighbors of activated T-cell
Neighbors of mesothelial cell
Neighbors of mononuclear phagocyte
Neighbors of capillary endothelial cell
Neighbors of immunocompetent cell
Neighbors of granulocyte
Neighbors of cardiac myocyte
Neighbors of cancer-associated fibroblast
Neighbors of myeloid cell
Neighbors of mesenchymal stroma cell
Neighbors of corneal epithelial cell
Neighbors of cytotrophoblast
Neighbors of stem cell
Neighbors of tumor infiltrating macrophage
Neighbors of sinusoidal cell
Neighbors of B-cell
Neighbors of granulosa cell
Neighbors of leukocyte
Neighbors of chondrocyte
Neighbors of insulin-secreting cell
Neighbors of mesenchymal cell
Neighbors of T-cell
Neighbors of M1 macrophage
Neighbors of myofibroblast
Neighbors of pancreatic stellate cell
Neighbors of mast cell
Neighbors of bone marrow stromal cell
Neighbors of spleen cell
Neighbors of brain capillary endothelial cell
Neighbors of neuroglia
Neighbors of thyroid epithelial cell
Neighbors of aortic smooth muscle cell
Neighbors of hematopoietic cell
Neighbors of podocyte
Neighbors of mammary epithelial cell
Neighbors of pericyte
Neighbors of epidermis cell
Neighbors of bone marrow derived mast cell
Neighbors of phagocyte
Neighbors of kidney cell
Neighbors of syncytiotrophoblast
Neighbors of lymphocyte
Neighbors of decidual natural killer cell
Neighbors of thymic epithelial cell
Neighbors of brain cell
Neighbors of M2 macrophage
Neighbors of peritoneum cell
Neighbors of lymphoid cell
Neighbors of retina cell
Neighbors of blood cell
Neighbors of skin cell
Neighbors of luteal cell
Neighbors of peripheral lymphocyte
Neighbors of activated B-cell
Neighbors of lung
Neighbors of liver
Neighbors of kidney
Neighbors of skin
Neighbors of intestine
Neighbors of lymph node
Neighbors of colon
Neighbors of airway
Neighbors of blood vessel
Neighbors of heart
Neighbors of aorta
Neighbors of gastrointestinal tract
Neighbors of microvessel
Neighbors of bone
Neighbors of placenta
Neighbors of carotid artery
Neighbors of synovial membrane
Neighbors of uterus
Neighbors of esophagus
Neighbors of periodontium
Neighbors of retina
Neighbors of brain
Neighbors of ovary
Neighbors of breast
Neighbors of blood vessel wall
Neighbors of stomach
Neighbors of islets of Langerhans
Neighbors of artery
Neighbors of cardiovascular system
Neighbors of pancreas
Neighbors of prostate
Neighbors of central nervous system
Neighbors of kidney glomerulus
Neighbors of lymphatic system
Neighbors of colorectal region
Neighbors of decidua
Neighbors of amnion
Neighbors of immune system
Neighbors of peritoneum
Neighbors of alveolus
Neighbors of coronary artery
Neighbors of left ventricle
Neighbors of uterine cervix
Neighbors of omentum
Neighbors of vein
Neighbors of arteriole
Neighbors of villus
Neighbors of bronchus
Neighbors of glands
Neighbors of nose
Neighbors of eye
Neighbors of cornea
Neighbors of hippocampus
Neighbors of intervertebral disc
Neighbors of mammary gland
Neighbors of vitreous body
Neighbors of cerebral cortex
Neighbors of brain blood vessel
Neighbors of bladder
Neighbors of nervous system
Neighbors of retina blood vessel
Neighbors of mesentery
Neighbors of nasopharynx
Neighbors of cervical lymph node group
Neighbors of periodontal ligament
Neighbors of trachea
Neighbors of corpus luteum of ovary
Neighbors of nerve
Neighbors of endocrine system
Neighbors of lower extremity
Neighbors of small intestine
Neighbors of aggregated lymphoid follicle of small intestine
Neighbors of knee joint
Neighbors of lymphatic vessels
Neighbors of pleura
Neighbors of Fallopian tube
Neighbors of hair follicle
Neighbors of NF-kB family
Neighbors of oxidized LDL
Neighbors of JNK
Neighbors of IL1 family
Neighbors of PPAR
Neighbors of Jun/Fos
Neighbors of NFKBI
Neighbors of PKC
Neighbors of PI3K
Neighbors of STAT family
Neighbors of mitogen-activated protein kinase
Neighbors of IFNAR ligand
Neighbors of transforming growth factor
Neighbors of TLR
Neighbors of cytokine
Neighbors of interferon
Neighbors of interleukin
Neighbors of JAK
Neighbors of MEK1/2
Neighbors of PDGF
Neighbors of Ras GTPase
Neighbors of ERK1/2
Neighbors of growth factor
Neighbors of PKA
Neighbors of ovalbumin
Neighbors of LDL
Neighbors of NF-AT family
Neighbors of beta adrenoceptor
Neighbors of chorionic gonadotropin
Neighbors of IKBK
Neighbors of adipokine
Neighbors of protein tyrosine kinase
Neighbors of NAD(P)H oxidase
Neighbors of IgG
Neighbors of SMAD subfamily
Neighbors of AMPK
Neighbors of LXR
Neighbors of HDL
Neighbors of p38
Neighbors of inflammatory cytokine
Neighbors of estrogen receptor
Neighbors of T-cell receptor
Neighbors of histone deacetylase
Neighbors of PDGF-BB
Neighbors of IL1R
Neighbors of HIF-1
Neighbors of GPCR
Neighbors of IL12
Neighbors of Notch
Neighbors of prostaglandin-endoperoxide synthase
Neighbors of heat shock protein 90
Neighbors of fibrinogen
Neighbors of aldehyde reductase
Neighbors of mitogen-activated protein kinase kinase
Neighbors of interleukin-35
Neighbors of TSH
Neighbors of Ang II receptor
Neighbors of endothelin
Neighbors of NOS
Neighbors of superoxide dismutase
Neighbors of proteasome endopeptidase complex
Neighbors of class nuclear receptor with C4 zinc fingers
Neighbors of non-coding RNA
Neighbors of histone H3
Neighbors of STAT5
Neighbors of alpha2 adrenoceptor
Neighbors of vitronectin receptor (integrin)
Neighbors of retinoid-X receptor subfamily
Neighbors of SAPK
Neighbors of WNT
Neighbors of gonadotropins
Neighbors of immunoglobulin
Neighbors of PP2B
Neighbors of phospholipase
Neighbors of AHR subfamily
Neighbors of ITG
Neighbors of endostatins
Neighbors of relaxin
Neighbors of TLR1/2 heterodimer
Neighbors of FSH
Neighbors of TORC1
Neighbors of angiotensin receptor
Neighbors of RA receptor
Neighbors of histone
Neighbors of Rho kinase
Neighbors of PDGF receptor
Neighbors of neuropeptides
Neighbors of pancreatic elastase
Neighbors of histone acetyltransferase
Neighbors of adrenoceptor
Neighbors of phosphodiesterase
Neighbors of caspase
Neighbors of deacetylase
Neighbors of TLR4/Myd88
Neighbors of TNF-alpha receptor
Model of PPARG signaling in psoriasis
PPARs and anxiety common targets
Amygdaloid expressed genes
IFN signaling in alveolar cells
Overview. Diseases of circulatory system (chapter 8)
Overview. Diseases of the skin (chapter 11)
Overview. Diseases of the eye (chapter 6)
Overview. Diseases of the respiratory (chapter 9)
Overview. Diseases of the genitourinary system (chapter 13)
2_Interleukin-17 and interleukin-22 signaling in psoriasis
1_TNF and IL1B provoke ECM degradation in osteoarthritis
1_Local estrogen production stimulates ectopic endometrium proliferation
3_Enhanced angiogenesis in endometriosis
2_Oxidative stress, all-trans-retinal, and lipofuscin toxicity in agerelated macular degeneration
3_Endoplasmic reticulum stress in age-related macular degeneration
1_Endothelial cells stimulate vasoconstriction and thrombosis in pulmonary hypertension
2_3_Eosinophilia and neutrophilia in asthma: Neutrophil chemotaxis and activation
2_2_Eosinophilia and neutrophilia in asthma: eosinophil apoptosis
4_1_Polymorphisms associated with inflammatory bowel diseases
3_Human papilloma virus E4 and E5 proteins in viral reproduction
5_Human papilloma virus E6 and E7 proteins promote epithelial cell proliferation
1_Microangiopathy in diabetic neuropathy
2_Mutations in SOD1 and associated proteins cause motor neuron death in familial ALS
drug-target pairs direct regulation
drug-target moltransport
New Combined Pathway
Interleukin-17 and interleukin-22 signaling in psoriasis

Group Genes with Mutations Associated with Psoriasis
Genes with Polymorphisms Associated with Migraine
Genes with Mutations Associated with Endometriosis
Genes with Susceptibility Loci Associated with Age-Related Macular Degeneration
Chemokines, Growth Factors and Receptors Involved in Cancer Cells Chemotaxis

Source GO component
curated

MedScan ID 7422

LocusLink ID 7422
22339
83785
558154
281572
797569
114601

Alias Vascular endothelial growth factor 121
VEGF120
VEGF121
VEGF164
vascular endothelial growth factor variant
vascular endothelial growth factor
RP1-261G23.1
MGC70609
OTTMUSP00000017463
OTTHUMP00000165987
vascular endothelial cell growth factor
vascular endothelial growth factors
OTTMUSP00000022244
vascular permeability factor
OTTMUSP00000022243
VEGF-A
vascular endothelial cells growth factor
VPF
vasculotropin
vascular endothelial growth factor isoform VEGF165
VEGF188
vascular endothelial growth factor A
OTTHUMP00000224107
VEGFA
OTTMUSP00000017464
vascular endothelial growth factor A121
GNB:37659
OTTMUSP00000022245
VEGF
VEGF165
VEGF111
vascular endothelial growth factor A165
MVCD1
Vascular endothelial growth factor precursor
Vascular permeability factor
VEGF164 protein
riken cdna g430002g23 gene
g430002g23rik
LOC558154
DKEY-14D8.3
chromosome
scaffold
si:dkey-14d8.3
LOC797569
similar to vascular endothelial growth factor

GO ID 0042056
0005125
0050840
0001968
0008083
0008201
0005161
0046982
0042803
0048018
0043183
0043184
0005172
0038190
0032147
0001525
0048844
0001569
0048754
0048593
0048739
0060948
0048469
0002042
0071456
0035924
0097533
0071679
0060982
0003169
0019221
0071542
0035767
0030855
0042462
0003007
0001701
0050930
0001822
0007595
0030324
0036303
0030225
0060749
0007498
0030224
0097475
1903392
0043066
2000048
0043154
1903141
0010629
0000122
0007399
0003151
0001541
0002576
0050918
0032793
0043406
0045766
0048842
0043536
1903589
0090190
0045785
0051781
0030335
0090050
0008284
0038091
0051272
0120162
0038033
0010595
0001938
0050679
0051894
0010628
1901727
0002687
0060754
0002053
0002052
1900745
0033138
1900086
0050731
0050927
0031954
0031334
0090037
1903572
0001934
0002092
1902336
1903672
0045944
0061419
0042531
0030949
0043117
0031077
0060319
0008360
0010749
0090259
0006357
0061418
0001666
0002040
0043129
0035148
0048010
0038084
0001570
0009986
0005913
0005737
0031012
0005576
0005615
0016020
0031093
0030141
0019838
0038191
0005102
0042088
0060978
0002575
0001568
0002043
0048514
0001974
0060346
0061430
0060326
0030154
0016477
0008283
0043542
0048873
0048286
0060426
0001946
0048255
0007275
0045779
0022408
0010719
2001237
0045599
0043524
1901215
0043069
0048666
2000573
0070374
1901492
0045669
0042327
0051897
1902966
0009967
0048661
0045601
0040008
1901532
0097601
0001944
0005604
0005634
0005886
0031982
0007568
0071549
0035690
0044344
0007565
0030212
0010469
0009409
0071548
0032355
0051593
0070482
0032570
0033189
0061304
0042060
0043185
0040007
0042517
0030823
0005578
0031988
0007596
2000273
0030168
1902533
0007610
2001028
0033554
0005515
0043498
0006916
0010740
0048008
0071445
0009968
0006950
0000074
0005786
0048595
0007165

KEGG ID hsa:7422
mmu:22339
rno:83785

MedLine Reference 17255303
12660426
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12007837
16930552
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9012841
12548213
12133520
15161709
15135240
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12133521
12060561
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15263820
17495954
12651930
15383400
17215071
12719950
15963467
8637916
16517614
15800063
11940521
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15653207
8119973
14551058
14532971
15540202
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16718361
12477932
2320579
15671530
17119993
10335479
17624309
12654193
12208074
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16077951
12057925
11784722
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11115828
10027415
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11867956
16412381
15583822
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8573716
11331305
15800930
15614129
10587525
11815711
14559444
12890722
11875709
15093699
12482858
15949234
12788875
10581076
12871382
17505039
15820807
11809716
11809713
11181640
15329326
12918061
12716911
12474525
12086892
16184401
16538528
17558601
15140761
17227294
12865814
12827055
15583754
12668280
15735682
10428027
16675573
16428272
17293873
12668286
12446667
11741977
16039638
15832056
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12665660
15273288
17467696
16603731
14729679
8614412
15193536
15785231
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16826426
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16054650
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16322068
15670761
15050899
15851615
14593238
12086877
11819817
16456664
15063179
10022836
7647376
12552636
11956584
12845559
15788755
11069235
11943666
17053052
14694016
16269156
16870555
12042276
8602242
8602241
14719060
15175265
15922088
12149254
17336974
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15284224
14513053
15492846
9336848
11163598
11509733
15633213
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12391145
16172161
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11861517
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12563064
17409493
17671399
12368264
17569125
15374715
12141529
15935515
15202016
12461084
15031673
17289903
12387457
16359995
16423853
2735925
15896327
12235106
11940485
14647449
8631822
16283008
15100155
11705851
12579315
16528367
15150105
15467755
12070272
17264168
12483534
12232762
16818728
12696078
15488701
15374730
16396910
15009103
15920019
16581961
16702519
16782887
11981751
15896317
17584582
12151391
11642726
11831981
17369464
12386279
17530707
16260429
16608813
17614845
12126787
11901189
12456629
17369472
15184386
17457373
16490744
16234975
17324777
15137063
16489641
14742307
12393646
17050862
16115033
9323936
15522212
17065333
17215390
17525262
15040022
15477409
15756443
9806910
11832343
16222693
9166595
17367506
15034080
11920479
11866530
11919510
16202216
11824377
16482425
16752188
16432214
16982461
12413884
15545635
15563592
15793222
15667531
11919509
12779248
12234794
11930687
16027358
14662796
12448348
12039984
16545694
12594002
14715242
16432225
10323857
10705382
12397601
16318581
15090854
8889548
16409998
12207021
16088182
15015550
16940309
11289156
10208743
12881220
17618600
15161630
14663468
12777375
16901919
15453815
15489334
12568850
11705867
11930688
12606532
12466305
16530326
12590639
11804779
17211450
16612574
17553957
14529579
15351965
15610240
16514669
15347673
15191350
14610338
12594815
14585871
16931798
7846076
9922142
15031602
15351862
15777969
11230154
16396768
7490564
16966370
11381259
1550962
17538775
14969389
16920734
12708473
14998491
15687494
17470563
11927538
17418408
16908180
16219308
12844492
17488794
12850503
11472838
12406876
15453394
1711045
12117969
15246970
16171822
15122338
12796773
11016853
12016145
16617130
2610687
16712976
14664702
17654674
16413500
15153787
16740682
16990600
10464055
12736220
16170370
9529250
12102661
15371263
11731620
16806288
10349636
15817666
10716993
12538631
15944181
12900522
16269210
11066091
16672722
14980515
11961303
15458440
16856151
15500293
15118294
15306695
15652753
12181492
15689378
12509426
17013884
12744932
12667326
12711260
12174901
10675351
12551914
17168735
12368217
12556420
15911882
11866538
15161688
12558813
16543500
12482957
15838884
11978667
16038988
15673567
12845630
9916007
11686329
11563986
11124112
17222790
17531158
16761623
14708636
15160911
17392174
14681237
15191555
15501249
16465407
17719546
15492987
16916659
15259010
17487399
16388189
14514674
16793871
12086595
15905202
15882861
14762365
12937129
11972026
11171333
11834731
16320826
16515588
15501243
15826815
10700190
15501241
16972327
11783119
14530359
12400015
15504975
15664512
17616354
15732116
15501235
9012504
16916647
16192634
12482580
17659575
17661998
17023682
15726914
11076861
15956982
16160062
16733790
15685607
15185205
16293653
12883688
11799077
16645174
16339827
14726393
14607712
14512791
12883692
16049374
14656735
10942527
15239258
16164632
17121831
11964077
2584205
12430738
12937141
15120936
12453985
11032698
11937493
17461470
14669345
11806247
17162607
12710853
10575000
15550485
15309707
7768934
12957716
11957147
8702615
14651929
10653008
17353160
16830384
14675094
16684540
15637071
17175233
14517396
16549155
14572781
16648151
16223785
12591230
16164642
16820871
16257644
15015562
16410746
10626738
15016731
17237427
14696965
17490619
14648803
11133233
16299233
16595708
16046504
12539040
15607642
12687277
12767510
16911686
16650815
16355211
14574404
16095053
16650817
17088559
11381139
11839570
12885771
17276402
15516835
16461129
10922068
12038454
12975317
12871881
12852851
16049137
16254334
14635718
14507641
12209725
11999550
15117722
15880052
14672622
15050532
16357200
14981918
14530810
12949011
14635716
15996656
16735996
9878851
15964546
16883594
17453634
12012273
14745002
16569553
14507649
15132990
15477421
12168898
11226286
17471570
12105188
11331753
14507446
15610528
10654595
11839592
15217952
15609122
14747470
17112680
17589348
14747750
12855698
12684660
15880074
12407018
10943840
14704231
11439183
8786112
17175272
17187775
11748975
15788677
8756616
17381847
15613470
15532726
12761846
16707486
12114504
15661856
15701844
12515393
14602779
15217947
15001987
12756808
9153276
11827992
16775835
16835467
12670505
15927453
15754412
17559806
16392034
15475194
12213803
15358155
12213806
12174896
15973775
15616224
15847702
11809675
12700666
15274325
12593846
14667896
12839933
12014632
10027394
15646833
16980969
1567395
15465485
17631682
15951295
16186493
14741347
16086118
8602835
17626901
14988276
15609132
11196464
15916974
8641698
12151344
10813585
15661835
16949073
11956638
15014023
7706320
9665379
15705187
12209585
15180964
12618525
16343055
16482999
16141073
16141072
7759509
11980898
10873597
16084492
10926756
8968091
9861052
11577200
12151311
15614762
17180351
16937522
14550787
15548611
17065555
16601840
17434451
16835828
12493399
17509958
12062186
15886312
17511025
12499259
12646239
17572843
16831171
15347840
7518352
9256442
16394111
16239639
16699073
14607580
17348020
17626736
12053176
17334879
16643910
15456771
10706142
16010973
12168808
14660505
15993383
16839256
16778129
11090062
17478585
7933988
12446788
12481883
12119553
16203926
15001532
16142870
15298982
15562207
16877353
12023772
12893367
15166499
14609725
7683699
12883661
7534783
15768385
11165481
12926153
16411082
12496364
12509854
11032855
11959648
11122379
14764596
16169405

Tissue Pancreatic islets
Tongue
Kidney
Pancreas
Testis interstitial
Uterus
Superior cervical ganglion
Uterus corpus
Bronchial epithelial cells
Salivary gland
Pb-bdca4+dentritic
Fetal thyroid
Pb-cd14+monocytes
Heart
Cardiac myocytes
Fetal brain
Atrioventricular node
Burkitts-daudi lymphoma
Adrenal gland
Appendix
bone marrow
Bm-cd105+endothelial
Bm-cd34+
Fetal lung
Burkitts-raji lymphoma
Temporal lobe
Leukemia chronic myelogenous(k562)
Testis germ cell
Trigeminal ganglion
adrenal cortex
Testis leydig cell
Skin
Whole brain
Pb-cd8+tcells
Pb-cd56+nkcells
thyroid
Placenta
skeletal muscle
Olfactory bulb
Bm-cd33+myeloid
smooth muscle
Ciliary ganglion
Prostate
Ovary
Trachea
Bm-cd71+early erythroid
Cerebellum
Lymphnode
Lung
Liver
Colorectal adenocarcinoma
Lymphoblasts
Pituitary
amygdala
tonsil
Fetal liver
Testis seminiferous tubule

Organism Homo sapiens {Organism urn:agi-taxid:9606}
Mus musculus {Organism urn:agi-taxid:10090}
Rattus norvegicus {Organism urn:agi-taxid:10116}
Homo sapiens
Mus musculus
Rattus norvegicus
Bos taurus
Danio rerio

Mouse chromosome position 17 22.79 cM
17 24.2 cM

OMIM ID 192240
603933
125853

Rat chromosome position 9q12

Hugo ID 12680
HGNC:12680

Human chromosome position 6p21.1
6p12

Swiss-Prot Accession A0A087WUD8
P15692
A0A087X0B2
A0A087WTP4
A0A087X1L1
A0A024RD33
A0A024RD37
A0A0Y0IMM4
A2A2V4
P15692.2
A0A1L1SVG2
Q00731
F6ZE01
Q00731.2
B5DEK7
P16612
Q541S7
A0A0G2K6Z7
P16612.2
B5BU86
H0Y2S8
H0Y407
H0Y414
H0Y462
H0Y8N2
H3BLW7
O60720
O75875
Q074Z4
Q16889
Q5UB46
Q6P0P5
Q96KJ0
Q96L82
Q96NW5
Q9H1W8
Q9H1W9
Q9UH58
Q9UL23
O70123
Q66S31
Q6GT23
Q6WZL9
Q541S6
Q91ZE1
Q9JKX7
Q9QXG6
Q9QXG7
Q59FH5
Q6WZM0
Q71S09
Q96FD9
Q9UNS8
A0FKR4
Q5UD54
Q6YLN3
Q80UA0
O88911
Q63672
Q64FZ6
Q78EG9
Q91V21
Q91Y66
Q91Y68
Q91ZE2
VEGFA_HUMAN
VEGFA_MOUSE
VEGFA_RAT
B5DEK7_RAT
Q541S7_RAT

PIR ID A41551
A44881
B44881
A35987

GenBank ID NC_000006
NM_001171623
NP_001165094
NM_001171624
NP_001165095
NM_001204384
NP_001191313
NM_001171625
NP_001165096
NM_001171626
NP_001165097
NM_001317010
NP_001303939
NM_001171629
NP_001165100
NM_001171627
NP_001165098
NM_001171628
NP_001165099
NM_001171630
NP_001165101
NM_001025366
NP_001020537
NM_003376
NP_003367
NM_001204385
NP_001191314
NM_001025367
NP_001020538
NM_001025368
NP_001020539
NM_001033756
NP_001028928
NM_001025369
NP_001020540
NM_001025370
NP_001020541
NM_001171622
NP_001165093
NM_001287044
NP_001273973
NG_008732
AF092126
AF095785
AAD04918
AF437895
AAL27630
AH001553
AAA36804
AH006909
AAC63101
AL136131
CH471081
EAX04227
EAX04228
EAX04229
EAX04230
EAX04231
EAX04232
EAX04233
EAX04234
EAX04235
CQ858312
CAH23417
CS067226
CAI84576
CS172363
CAJ32889
CS172373
CAJ33665
CS367293
CAL32723
CS367438
CAL33850
HC040683
CBH30534
HC040693
CBH30539
Y08736
AB021221
BAA78418
AB209485
BAD92722
AB451322
BAG70136
AB451451
BAG70265
AF022375
AAC63143
AF024710
AF062645
AAC16730
AF091352
AAD55345
AF214570
AAF19659
AF323587
AAQ14857
AF430806
AAL27435
AF486837
AAM03108
AJ010438
CAA09179
AK056914
AK125666
AY047581
AAK95847
AY263145
AAP86646
AY500353
AY766116
AAV34601
BC011177
AAH11177
BC019867
BC058855
BC065522
AAH65522
BF700556
BM661679
BQ880667
BU153227
BX442364
CN256173
CX756573
DA237741
DQ229900
ABB58912
HY066915
KT581010
AMB36732
KT581011
AMB36733
M27281
AAA36807
M32977
AAA35789
S85192
AAC63102
X62568
CAA44447
P15692
NC_000083
NM_001025257
NP_001020428
NM_001287058
NP_001273987
NM_009505
NP_033531
NM_001287057
NP_001273986
NM_001317041
NP_001303970
NM_001025250
NP_001020421
NM_001287056
NP_001273985
NM_001110268
NP_001103738
NM_001110267
NP_001103737
NM_001110266
NP_001103736
AB086118
BAC54913
AC127690
AF317892
CH466559
EDL23467
U41383
AK031905
AK131850
AW913188
AY120866
AAM55477
AY263146
AAP86647
AY707864
AAU11325
AY750956
AAU95484
AY750957
AAU95485
AY756068
AAV32504
BC022642
BC061468
AAH61468
BQ554097
BQ832724
BU920197
BY001490
CA321456
CK626177
EF028705
ABK27265
HQ712122
ADY05339
M95200
AAA40547
S37052
AAB22252
S38083
AAB22253
S38100
AAB22254
U50279
AAC05442
Q00731
NC_005108
NR_105011
NM_031836
NP_114024
NM_001287107
NP_001274036
NM_001287111
NP_001274040
NM_001287112
NP_001274041
NM_001110333
NP_001103803
NM_001287108
NP_001274037
NM_001317043
NP_001303972
NM_001110334
NP_001103804
NM_001287110
NP_001274039
NM_001287113
NP_001274042
NM_001287114
NP_001274043
NM_001110335
NP_001103805
NM_001110336
NP_001103806
AC_000077
AAHX01058303
AC108326
CH473987
EDM18768
EDM18769
EDM18770
EDM18771
EDM18772
EDM18773
EDM18774
EDM18775
EDM18776
EDM18777
EDM18778
EDM18779
EDM18780
EDM18781
EDM18782
EDM18783
EDM18784
EDM18785
EDM18786
EDM18787
EDM18788
U22372
AF062644
AAC16448
AF080594
AAC36708
AF215725
AAF19211
AF215726
AAF19212
AF222779
AAF25958
AF260425
AAK49396
AF261751
AAK49408
AY033503
AAL07523
AY033504
AAL07524
AY033505
AAL07525
AY033506
AAL07526
AY033507
AAL07527
AY033508
AAL07528
AY378102
AY702972
AAU36606
BC168708
AAI68708
BQ203400
CB718631
CB810370
CK357826
CK358638
CK364938
CK602714
CO565920
CV107730
EU040284
ABW02818
EU040285
ABW02819
GQ423618
ACV52076
KT971352
APA62567
L20913
AAA42334
M32167
AAA41211
P16612
NC_018917
AMYH02013650
M63971
M63972
M63973
M63974
M63975
M63976
M63977
M63978
BC172307
AAI72307
EU832814
ACE87825
GQ129408
ACT64542
AC_000039
AAHY01132989
AAHY01132990
AAHY01132991
ABBA01050660
AC_000138
XM_005249363
XP_005249420
AABR06058825
CAC19516
CAC19515
CAC19512
CAC19513
CAM28207
NT_007592
NW_001838981
NW_923073
AC_000049
S85224
CR592173
CR614384
Q59FH5
Q6WZM0
Q71S09
Q96FD9
Q9UNS8
NT_039649
NW_001030618
A0FKR4
Q5UD54
Q6YLN3
Q80UA0
NW_047813
NW_001084880
O88911
Q541S7
Q63672
Q64FZ6
Q78EG9
Q91V21
Q91Y66
Q91Y68
Q91ZE2
108742042
26352764
32699992
32699990
3719221
DQ150576
AW045851
AAI39620
53850882
340215
53850884
81903235
81903237
81903236
119624636
119624637
119624634
119624635
119624638
62088550
119624639
NT_086693
119624632
119624633
NW_001511339
56207996
3647281
68300769
74749493
3712669
81867318
AK194109
37545172
BC139619
181971
Q5RHW5
119624640
3712671
BAE43236
74712795
81871539
81871538
81867478
340301
Q8C2W6
NP_444482
137819
204288
13435566
148701219
148701218
81903015
6708500
BG073936
AAA30805
AAA30804
NW_001494158
81886901
19909065
116794760
M31836
148701220
148701221
81174728
BC004660
5901561
54401695
38181775
123915392
37659
Q99MS7
11989985
11989982
11989983
3643123
Q99MS6
Q99MS5
CAC19514
Q541S6
NT_082868
54299287
347168
81887482
81887483
149069339
149069338
149069337
149069336
NT_039655
3133495
81895034
149069335
27544279
149069334
AI606078
149069333
149069332
149069331
Q1ECU5
NC_007115
149069330
AK013080
AK089917
149069329
149069328
121944495
149069327
NP_776641
NC_007127
AAK32109
81890482
82196427
74213693
81876237
4154291
NM_174216
17380502
74741195
AAK32112
AAK32110
XM_001334409
AAK32111
DQ026828
52301743
AK169974
123797854
NW_000140
81889721
16612070
AK087817
148691520
M33750
AC_000041
NW_000130
AAA30502
163007
163811
XM_001334310
13925663
13925623
AAH04660
Q99J97
163809
NC_000085
NC_007324
BX324164
123241442
81893496
15822721
123906799
15822725
15822723
BB099233
AF305087
AF305088
AF305089
NM_053252
15822717
15822719
15822715
33340525
202351
17380528
AF305090
NM_001044855
BC117665
NW_001513217
M32976
110611814
Q3V443
75858341
EDL33166
CH466612
EDL33167
EDL33168
EDL33165
110611802
AAI17666
6631029
AA959550
XP_001334346
15422109
ABA28744
145337885
2951983
1718156
16660686
Q1ANK8
AC134563
249861
249857
249859
4996351
BAC40012
CAI19965
13604145
6606566
13604143
6606564
P15691
13604149
13604147
51860167
NW_001030639
NP_001038320
CAI20661
123781165
81865004
3139081
149069347
149069346
AAY89335
149069345
XP_001334445
149069344
149069343
149069342
149069341
149069340
AK217724
81872143
74721192
113931650
125838831
125838833
113931651
126007509
126006804
558154
Dr.79865
ZDB-GENE-041210-111
dre:558154
797569
AF016244
AF059661
NM_131408
dre:797569

Swiss-Prot ID VEGFA_HUMAN
VEGFA_MOUSE
VEGFA_RAT
Q541S7_RAT
B5DEK7_RAT

Cell Localization Secreted
Cell membrane
Extracellular

Ensembl ID ENSG00000112715
ENSP00000361125.4
ENST00000372055.8
ENSP00000389864.3
ENST00000413642.7
ENSP00000361137.3
ENST00000372067.7
ENSP00000388663.2
ENST00000417285.6
ENSP00000361134.4
ENST00000372064.8
ENSP00000421561.1
ENST00000482630.6
ENSP00000317598.6
ENST00000324450.10
ENSP00000430479.1
ENST00000523873.5
ENSP00000428321.1
ENST00000520948.5
ENSP00000430829.1
ENST00000518689.5
ENSP00000429643.1
ENST00000523950.5
ENSP00000429008.1
ENST00000523125.5
ENSP00000361148.4
ENST00000372077.8
ENSP00000430002.1
ENST00000518824.5
ENSP00000409911.2
ENST00000457104.6
ENSP00000430594.1
ENST00000519767.5
ENSP00000230480.6
ENST00000230480.10
ENSP00000388465.2
ENST00000425836.6
ENSMUSG00000023951
ENSMUSP00000115883.2
ENSMUST00000142351.8
ENSMUSP00000131901.2
ENSMUST00000167860.8
ENSMUSP00000109148.1
ENSMUST00000113520.7
ENSMUSP00000024747.7
ENSMUST00000024747.13
ENSMUSP00000071575.5
ENSMUST00000071648.11
ENSRNOG00000019598
ENSRNOP00000026559.3
ENSRNOT00000026559.5
ENSRNOP00000050127.2
ENSRNOT00000044163.4
ENSRNOP00000047820.3
ENSRNOT00000042790.3
ENSRNOP00000074002.1
ENSRNOT00000083811.1
ENSRNOP00000026637.4
ENSRNOT00000026637.7
ENSP00000478570
ENST00000611736
ENSP00000389864
ENST00000413642
ENSP00000483241
ENST00000621747
ENSP00000388663
ENST00000417285
ENSP00000478034
ENST00000615393
ENSP00000421561
ENST00000482630
ENSP00000484284
ENST00000617771
ENSP00000430479
ENST00000523873
ENSP00000428321
ENST00000520948
ENSP00000430829
ENST00000518689
ENSP00000429643
ENST00000523950
ENSP00000429008
ENST00000523125
ENSP00000361148
ENST00000372077
ENSP00000430002
ENST00000518824
ENSP00000409911
ENST00000457104
ENSP00000430594
ENST00000519767
ENSP00000230480
ENST00000230480
ENSP00000388465
ENST00000425836
ENSMUSP00000115883
ENSMUST00000142351
ENSMUSP00000131901
ENSMUST00000167860
ENSMUSP00000109148
ENSMUST00000113520
ENSMUSP00000024747
ENSMUST00000024747
ENSMUSP00000071575
ENSMUST00000071648
ENSRNOP00000026559
ENSRNOT00000026559
ENSRNOP00000050127
ENSRNOT00000044163
ENSRNOP00000047820
ENSRNOT00000042790
ENSRNOP00000074002
ENSRNOT00000083811
ENSRNOP00000026637
ENSRNOT00000026637
ENST00000372067
ENSP00000361137
ENSP00000361134
ENST00000372064
ENST00000324450
ENSP00000361125
ENST00000372055
ENSP00000317598

MGI ID MGI:103178
103178
3612340

RGD ID 619991

Unigene ID Rn.1923
Mm.282184
Hs.73793
Mm.477156
Dr.79865
Mm.210447
Mm.470969
Bt.4138

Homologene ID 2534

Shape Rhomb

IPI ID IPI00402915
IPI00656297
IPI00231977
IPI00607893
IPI00012567
IPI00954880
IPI00955048
IPI00954971
IPI00852889
IPI00955379
IPI00940477
IPI00214604
IPI00829762
IPI00327982
IPI00216555
IPI00954917
IPI00216553
IPI00475372
IPI00209785
IPI00989633
IPI00954943
IPI00374772
IPI00989242
IPI00915448
IPI00872936
IPI00555908
IPI00793077
IPI00436015
IPI00216554
IPI00064652
IPI00607783
IPI00467967
IPI00223442
IPI00877296
IPI00877306
IPI00877273
IPI00831263
IPI00830961
IPI00214186
IPI00199066
IPI00877356

Microarray ID 212171_x_at
103520_at
210512_s_at
1416804_at
1448467_a_at
1451959_a_at

Homo sapiens Chromosome position 6p12

Ensembl Transcript ID ENST00000372055
ENST00000372064
ENST00000372067
ENST00000531781
ENST00000372077
ENST00000520948
ENST00000523950
ENST00000523873
ENST00000457104
ENST00000518689
ENST00000425836
ENST00000518824
ENST00000324450
ENST00000523125
ENST00000531362
ENST00000413642
ENST00000532514
ENST00000482630
ENST00000530947
ENST00000417285

FunctionalClass heparin binding
protein binding
extracellular matrix binding
protein homodimerization
vascular endothelial growth factor receptor binding
growth factor

Bos taurus Chromosome position 23

Mus musculus Chromosome position 17 24.2 cM
19 A

KEGG pathway Renal cell carcinoma
Focal adhesion
Pancreatic cancer
mTOR signaling pathway
VEGF signaling pathway

Rattus norvegicus Chromosome position 9q12

Ensembl Gene ID ENSG00000112715

LocatorString pmftq:oncomed
pmquery:invasive+breast+cancer
digtext:C:\Users\Ariadne\Customers\Elan\Elan weekly report from literature condensed.txt
gscquery:curcumin+prostate+cancer