Protein IL22RA1

URN urn:agi-llid:58985
Total Entities 0
Connectivity 444
Name IL22RA1
Description interleukin 22 receptor subunit alpha 1
Notes The protein encoded by this gene belongs to the class II cytokine receptor family, and has been shown to be a receptor for interleukin 22 (IL22). IL22 receptor is a protein complex that consists of this protein and interleukin 10 receptor, beta (IL10BR/CRFB4), a subunit also shared by the receptor complex for interleukin 10 (IL10). This gene and interleukin 28 receptor, alpha (IL28RA) form a cytokine receptor gene cluster in the chromosomal region 1p36. [provided by RefSeq, Jul 2008]
Primary Cell Localization Plasma membrane
Class Receptor

Pathway AHR in Intestinal Cell Antimicrobial Barrier Maintenance
IL22 Induces Keratinocyte Proliferation in Psoriasis
Keratinocyte Activation in Psoriatic Arthritis
Elevated Receptors -> Expression Targets in Colon
STAT3 and NFkB Activate Inflammation-Induced Tumorigenesis
IL22R -> STAT3 Signaling
IL22 Expression Targets
2_Interleukin-17 and interleukin-22 signaling in psoriasis
1_Inflammatory mediators increase the production of hepcidin (HAMP)
Interleukin-17 and interleukin-22 signaling in psoriasis

MedScan ID 58985

LocusLink ID 58985
230828
362629

Alias CRF2 IX
OTTMUSP00000010252
interleukin IL22RA1
IL-22R-alpha-1
RP23-110F21.4
IL22 receptors
IL22 Rs
interleukin IL22 receptor
interleukin IL22R1
IL22 receptor, alpha I
IL-TIF receptors
IL22 receptor, alpha 1
IL-22 receptor
interleukin IL22 receptor, alpha 1
interleukin IL22 Rs
IL10-related T-cell derived inducible factor receptor
RIKEN cDNA 9130219A07 gene
interleukin 22 receptor, alpha I
IL22R1
9130219A07Rik
LOC279229
IL-22 receptor subunit alpha-1
interleukin IL22 R
RGD1559655
IL-TIF receptor
IL22 receptor, alpha
interleukin IL22RA I
IL22RA1
interleukin 22 receptors
CRF2-9
interleukin IL22 receptor, alpha I
interleukin-22 receptor subunit alpha-1
OTTHUMP00000003073
interleukin IL22 receptor, alpha
interleukin 22 receptor, alpha 1
IL22RA I
IL22 R
cytokine receptor class-II member 9
interleukin 22 receptor
interleukin IL22 receptors
interleukin 22 receptor, alpha
zcytoR11
cytokine receptor family 2 member 9
ENSMUSG00000073746
IL22R
IL-22RA1
IL-22R
interleukin-22 receptor alpha chain

GO ID 0004896
0004904
0042015
0019221
0050829
0016021
0005886
0016020

KEGG ID hsa:58985
mmu:230828

Organism Homo sapiens {Organism urn:agi-taxid:9606}
Mus musculus {Organism urn:agi-taxid:10090}
Rattus norvegicus {Organism urn:agi-taxid:10116}
Homo sapiens
Mus musculus
Rattus norvegicus

Mouse chromosome position 4 67.99 cM

OMIM ID 605457

Rat chromosome position 5q36

Hugo ID 13700
HGNC:13700

Human chromosome position 1p36.11

Swiss-Prot Accession Q8N6P7
Q8N6P7.1
Q3TS18
Q80XZ4
Q80XZ4.1
D3ZIM3
A8K839
B2R9Y9
Q9HB22
B2RU51
Q3URP9

GenBank ID NC_000001
XM_011541882
XP_011540184
NM_021258
NP_067081
AL590683
AL591178
CH471134
EAW95111
AF286095
AAG22073
AK226001
AK292204
BAF84893
AK304454
BAG65271
AK308522
AK313971
BAG36686
BC014096
BC029273
AAH29273
Q8N6P7
NC_000070
NM_178257
NP_839988
AL662911
CH466552
EDL29970
CQ889915
CAH61680
CQ889977
CAH61684
CS425176
CAL60110
CS719569
CAP40191
HC888946
CBM42928
AK141289
BAE24639
AK162333
BAE36858
AY103454
AAM52222
BC140972
AAI40973
BC140973
AAI40974
Q80XZ4
NC_005104
NM_001191869
NP_001178798
AC_000073
AABR07050165
AABR07050166
AABR07073177
AAHX01040257
AAHX01040258
AC135901
CH473968
EDL80765
EDL80766
NC_018912
AMYH02000517
JF432213
ADZ15430
AC_000026
AAHY01040791
AAHY01040792
AC_000133
ABBA01059898
ABBA01059899

Swiss-Prot ID I22R1_HUMAN
I22R1_MOUSE

Cell Localization Membrane

Ensembl ID ENSG00000142677
ENSP00000270800.1
ENST00000270800.2
ENSMUSG00000037157
ENSMUSP00000099605.3
ENSMUST00000102546.3
ENSRNOG00000027976
ENSRNOP00000037743.4
ENSRNOT00000031512.6
ENSP00000270800
ENST00000270800
ENSMUSP00000099605
ENSMUST00000102546
ENSRNOP00000037743
ENSRNOT00000031512

MGI ID MGI:2663588

RGD ID 1559655

Unigene ID Hs.110915
Mm.261647
Rn.95852

Homologene ID 10943

Shape Stick-vertex