Small Molecule ROS

URN urn:agi-smol:ROS
Total Entities 0
Connectivity 13892
Name ROS
Class Endogenous compound

Pathway Alzheimer's Disease
Skin Aging
Apoptosis of Cochlear Hair Cells (Noise-Induced, Mouse Model)
Oncogene Induced Cellular Senescence
Melatonin Effects on Circadian Cycle
SIRT6 Signaling in Aging
SIRT1 Signaling in Aging
Fatty Acids Cause Oxidative Stress and Mitochondria Decline in Aging
Protein Oxidation and Aggregation in Aging
Extracellular Matrix Reformation in Aging
NOD-like Receptors
Scavenger Receptors in Platelet Activation
Toll-like Receptor Independent Sterile Inflammation
Necrosis
Lipoxin A4/FPR2-Related Neutrophil Depression
Eicosanoids in Inflammation
Neutrophil Activation via LTB4/Polyisoprenyl Phosphate Signaling
Eosinophil Activation
Macrophage M1 Lineage
CD16/CD14 Proinflammatory Monocyte Activation
Neutrophil Activation via FCGR3B
Neutrophil Degranulation via FPR1 Signaling
Neutrophil Chemotaxis
Neutrophil Activation via Adherence on Endothelial Cells
Melatonin in Cell Survival and Antioxidant Response
Scavenger Receptor OLR1 in Inflammation Related Endothelial Dysfunction
RAGE/AGER and S100 Proteins in Cardiovascular Injury
Dilated Cardiomyopathy
Endothelial Cell Dysfunction in Pulmonary Hypertension
Smooth Muscle Cell Dysfunction in Pulmonary Hypertension
Reperfusion Injury in Myocardial ischemia
Myocardial Infarction
Preconditioning Ischemia
Vascular Reactivity in Raynaud Disease
Cold Stress and Adrenoceptor alpha 2C Signaling in Raynaud Disease
NO Synthesis in Early Vasospasm
Hemoglobin Reduction and Leukocyte Adhesion Initiate Vasospasm
Sebocyte Proliferation in Acne Vulgaris
Androgens Synthesis in Sebocytes
Cell Cycle Dysregulation in Melanoma
Melanoma
MITF as a Regulator of Melanoma Cell Development
Extracellular Matrix Degradation in Skin Aging
Melanocyte Role in Skin Aging
Apoptotic Keratinocytes Clearance Recession in Systemic Lupus Erythematosus
Plasmacytoid Dendritic Cell in Diabetes Mellitus Type 1
Toll-like Receptors in beta-Cell
Macrophage Function in Diabetes Mellitus Type 1
Conventional Dendritic Cell Role in Diabetes Mellitus Type 1
beta-Cell Death in Diabetes Mellitus Type 2
Advanced Glycation End Products Pathway in Diabetic Microangiopathy
Polyol Pathway in Diabetic Microangiopathy
Peripheral Tissue Microangiopathy
Tubular Cell Dysfunction in Progressive Diabetic Nephropathy
Endothelial Cell Dysfunction in Early Diabetic Nephropathy
Oxidative Stress in Diabetic Neuropathy
AGE Related Insulin Resistance in Skeletal Muscles
Lipid Metabolism Impairement in non-Alcoholic Fatty Liver Disease
beta-Cell Recovery in Diabetes Mellitus
Hyperglycemia and Hyperlipidemia Trigger beta-Cell Apoptosis
FOXO1 and SREBP-1C Role in beta-Cell Suppression (Rodent Model)
Hashimoto's Thyroiditis
Hashimoto's Thyroiditis Triggers
Fatty Acids in Hypertension and Atherosclerosis Development
Macrophage Dysfunction
Eosinophil Survival in Asthma
Eosinophil Activation and Degranulation in Asthma
Airway Smooth Muscle Cell Contraction
Neutrophil Degranulation via FPR1/IL8
CFTR Facilitates Oxidative Stress in Airway Epithelium in CF
Airway Epithelial Cell Dysfunction
Monocytes Function in Gout
Dendritic Cell Dysfunction in Psoriatic Arthritis
Skin Fibrosis
PAPA Syndrome
TNF Receptor Associated Periodic Syndrome
Cryopyrin (NLPR3) Associated Periodic Syndromes
Familial Cold Autoinflammatory Syndrome 2
Familial Mediterranean Fever
Glutamate Toxiicity Effects on Striatum Medium Spiny Neurons in Hantington's Disease
IL6 Overexpression After Contraction in Skeletal Muscles in Muscular Dystrophies
Muscular Dystrophies
Dystrophin Glycoprotein Complex Signaling in Muscular Dystrophies
Ca2+ Toxicity in Neurons
Ketogenic Diet Mechanism (Hypothesis)
PARK7 and LRRK2 in Young Onset Parkinson's Disease
Neurotoxin Effects in Parkinson's Disease
SNCA in Young Onset Parkinson's Disease
Glutamate Mediated Excitotoxicity in Amyotrophic Lateral Sclerosis
Oxidative Stress, All-Trans-Retinal and Lipofuscin Toxicity in AMD
Ca2+ Toxicity in Lens Cells
Diabetes Induced Cataract
Age-Related Cataract
Cataract, Congenital
Aminoglycosides and Cisplatin Induced Ototoxicity (Mouse Model)
Immune System Role in Otitis Media
Alveolar Macrophages Dysfunction in COPD
Neutrophil Associated Lung Damage in Chronic Obstructive Pulmonary Disease
CAV1 Dependent Senescence of Lung Fibroblasts
VEGFA High Expression Level in Pulmonary Emphysema
T-Cell Cytotoxic Activation
Mucin Hyperproduction in Goblet and Mucous Cells
Penile Detumescense Augmentation Mechanisms
Advanced Glycation End Products in Diabetes or Age Related Erectile Dysfunction
Ammonia Effects on Brain Cells
CD157/ITGB2 Signaling in Myeloid Cell
Acetaminophen Induced Hepatotoxicity
Asbestosis- and Silicosis-Associated Inflammation Provokes Cancer Development
Oxidized LDL/OLR1 Activates Cell Proliferation in Cancer
HIF1A as Master Regulator of Angiogenesis in Cancer
Invadopodia Formation in Cancer Cells
Respiratory Chain Impairment in Cancer
Metabolic Effects of Oncogenes and Tumor Suppressor in Cancer Cells
Glutamine in Cancer Metabolism
Tumor Infiltrating Macrophages in Cancer Progression and Immune Escape
Myeloid Derived Suppressor Cells in Cancer Immune Escape
HIF1 Signaling
ER Stress (Unfolded Protein Response)
Oxidative Stress Protection via AHR-NFE2L2-NQO1 Signaling in Keratinocytes
e
pathway 4
sialic
Model of PPARG signaling in psoriasis
2_Hyperseborrhea in acne vulgaris
2_Oxidative stress, all-trans-retinal, and lipofuscin toxicity in agerelated macular degeneration
2_Diabetes-induced cataract
3_Congenital cataract
1_Age-related cataract
1_Low-density lipoprotein internalization and the accumulation of lipids in atherosclerosis
3_Arterial wall inflammation and calcification in atherosclerosis
2_The intense proliferation and contractile activity of smooth muscle cells in pulmonary hypertension
1_Cigarette smoke causes dysfunction and production of inflammatory mediators in alveolar epithelial cells
3_Role of alveolar macrophages in pulmonary tissue destruction in COPD
2_3_Eosinophilia and neutrophilia in asthma: Neutrophil chemotaxis and activation
4_1_Airway smooth muscle cells contraction
1_Antigen-presenting cells promote islet dysfunction and immune system activation in T1D
1_Microangiopathy in diabetic neuropathy
1_Glutamate and calcium excitotoxicity of motor neurons in ALS
Figure 4_Diabetes mellitus Type 1: conventional dendritic cell

MedScan ID 1810338

Alias free oxygen species
oxygen radicals
oxygen radical
reactive oxygen intermediates
ROS
free oxygen radical
oxygen free radicals
reactive oxygen species
oxygen free radical
free oxygen radicals