Protein S100A9

URN urn:agi-llid:6280
Total Entities 0
Connectivity 1908
Name S100A9
Description S100 calcium binding protein A9
Notes The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in the inhibition of casein kinase and altered expression of this protein is associated with the disease cystic fibrosis. This antimicrobial protein exhibits antifungal and antibacterial activity. [provided by RefSeq, Nov 2014]
ObjectType Protein

Pathway AHR in Intestinal Cell Antimicrobial Barrier Maintenance
Proteins Involved in Atherosclerosis
RAGE/AGER and S100 Proteins in Cardiovascular Injury
IL22 Induces Keratinocyte Proliferation in Psoriasis
Proteins with Altered Expression in Psoriasis
Dendritic Cells Function in Psoriasis
Dendritic Cell Dysfunction in Psoriatic Arthritis
Immune System Role in Otitis Media
Proteins Involved in Bronchiectasis
Proteins Involved in Chronic Obstructive Pulmonary Disease
Myeloid Derived Suppressor Cells in Cancer Immune Escape
IFNG/IFNR Expression Targets
IL6 Expression Targets
TNF -> STAT Expression Targets
TLR4 -> AP-1/EGR1/HIF1A Expression Targets
IL1A Expression Targets
VEGFA -> STAT Expression Targets
dsRNA induces innate immunity and INFs in alveolar cells
AGER feed forward loop in innate immunity
2_Interleukin-17 and interleukin-22 signaling in psoriasis
3_Arterial wall inflammation and calcification in atherosclerosis
Interleukin-17 and interleukin-22 signaling in psoriasis

MedScan ID 6280

LocusLink ID 6280
20202
94195

Alias S100a9
OTTHUMP00000015331
LIAG
calprotectin L1H subunit
MAC387
intracellular calcium-binding protein (MRP14)
migration inhibitory factor-related protein
CGLB
calgranulin B
S100 calcium binding protein A9
S109
gagb
myeloid-related protein 14
AW546964
OTTMUSP00000032973
CAGB
Migration inhibitory factor-related protein 14
MRP14
S100 calcium binding protein A9 (calgranulin B)
Leukocyte L1 complex heavy chain
bee22
S109_HUMAN
MIF
NIF
P14
CFAG
L1AG
60B8AG
MRP-14
protein S100-A9
S100 calcium-binding protein A9
calgranulin-B
S100 calcium-binding protein A9 (calgranulin B)

GO ID 0050786
0035662
0016209
0050544
0005509
0008017
0008270
0006919
0061844
0019730
0006915
0006914
0007267
0098869
0032602
0001816
0042742
0050832
0006954
0045087
0002523
0035821
0070488
0030593
0043312
0035606
0051092
0030307
0050729
2001244
0010976
0051493
0032119
0002224
0030054
0062023
0005737
0005856
0005829
0070062
0005576
0005615
0005654
0005634
0005886
0034774
0046872
0031532
0014002
0035425
0006935
0002376
0030595
0018119
0030194
0002793
0050727
0045113
0006417
0016020
0002544
0045471
0032496
0010043
0006917
0007165
0005515
0004871
0005730

KEGG ID hsa:6280
mmu:20202
rno:94195

Organism Homo sapiens {Organism urn:agi-taxid:9606}
Mus musculus {Organism urn:agi-taxid:10090}
Rattus norvegicus {Organism urn:agi-taxid:10116}
Mus musculus
Homo sapiens
Rattus norvegicus

Mouse chromosome position 3 39.91 cM
3 43.6 cM

OMIM ID 123886

Rat chromosome position 2q34

Hugo ID 10499
HGNC:10499

Human chromosome position 1q21.3
1q21

Swiss-Prot Accession P06702
P06702.1
P31725
Q3UP42
P31725.3
P50116
A0A0H2UHJ1
P50116.3
D3DV36
Q6FGA1
Q9NYM0
Q9UCJ1
Q761U7

PIR ID B31848
S68242
JN0686

GenBank ID NC_000001
NM_002965
NP_002956
A12029
CAA01002
A12031
CAA01003
A12032
CAA01004
AF237581
AAF62536
AF237582
AAF62537
AL591704
CH471121
EAW53333
EAW53334
M21064
AAA36326
AF086362
AK311882
BAG34823
BC047681
AAH47681
CR542207
CAG47003
CR542224
CAG47020
M26311
AAA68480
X06233
CAA29579
P06702
NC_000069
NM_009114
NP_033140
NM_001281852
NP_001268781
AC122425
AJ250496
CAC14292
CH466547
EDL15109
EDL15110
AK143826
BAE25555
BC027635
AAH27635
BF732133
BY112406
M83219
AAB07228
P31725
NC_005101
XM_006232780
XP_006232842
NM_053587
NP_446039
AC_000070
AAHX01018654
AC097705
CH473976
EDM00535
AB118215
BAC82423
L18948
AAA18214
P50116
AAHY01029034
CAI19494
ABBA01049433
AABR06018860
AC_000133
NC_018912
AC_000025
AMYH02001902

Swiss-Prot ID S10A9_HUMAN
S10A9_MOUSE
S10A9_RAT

Cell Localization Secreted
Cytoplasm
Cytoskeleton
Cell membrane
Cytoplasm, cytoskeleton

Ensembl ID ENSG00000163220
ENSP00000357727.3
ENST00000368738.4
ENSMUSG00000056071
ENSMUSP00000070842.5
ENSMUST00000069960.11
ENSMUSP00000112843.1
ENSMUST00000117167.1
ENSRNOG00000011483
ENSRNOP00000015351.3
ENSRNOT00000015351.5
ENSMUSP00000112843
ENSRNOT00000015351
ENST00000368738.3
ENSMUSP00000070842
ENSP00000357727
ENSMUST00000117167
ENST00000368738
ENSRNOP00000015351
ENSMUST00000069960

MGI ID MGI:1338947
1338947

RGD ID 620267

Unigene ID Rn.6703
Hs.112405
Mm.2128

Homologene ID 2227

IPI ID IPI00027462
IPI00231262
IPI00222556