Protein RAC1

URN urn:agi-llid:5879
Total Entities 0
Connectivity 6321
Name RAC1
Description ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
Notes The protein encoded by this gene is a GTPase which belongs to the RAS superfamily of small GTP-binding proteins. Members of this superfamily appear to regulate a diverse array of cellular events, including the control of cell growth, cytoskeletal reorganization, and the activation of protein kinases. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
Primary Cell Localization Cytoplasm
ObjectType Protein

Pathway Oxidative Stress in Amyotrophic Lateral Sclerosis
Osteoarthritis
Skin Aging
Apoptosis of Cochlear Hair Cells (Noise-Induced, Mouse Model)
Dopamine Receptors Signaling
Thyroid Hormones Common non-Genomic Effects in Hyperthyroidism
Toll-like Receptors Act through MYD88-TIRAP Signaling
T-Cell Dependent B-Cell Activation
T-Cell Independent B-Cell Activation
Natural Killer Cell Activation through C-Type Lectin-like Receptors
Natural Killer Cell Activation through ITAM-Containing Receptors
Natural Killer Cell Inhibitory Receptor Signaling
Natural Killer Cell Activation through ITSM-Containing Receptors
Natural Killer Cell Activation through Integrins and non-ITAM-Containing Receptors
Natural Killer Cell Activation
CXC Chemokine Receptor Signaling
CC Chemokine Receptor Signaling
Plasmin Effects in Inflammation
Platelet Activation via Adhesion Molecules
Scavenger Receptors in Platelet Aggregation
Bradykinin Effects in Inflammation
Platelet Activation via GPCR Signaling
Toll-like Receptors in Sterile Inflammation
Toll-like Receptor Independent Sterile Inflammation
Lipoxin A4/FPR2-Related Neutrophil Depression
Do not Eat me\xc2\x9d Signal: Viable Cells Inhibits Phagocytosis
Eat me Signal: Apoptotic Cell Induces Phagocytosis
Neutrophil Activation via LTB4/Polyisoprenyl Phosphate Signaling
Basophil Activation
Eosinophil Activation
Mast-Cell Activation via IgE Signaling
Mast-Cell Activation without Degranulation
Mast-Cells De Novo Synthesized Mediators via IgE Independent Signaling
Mast-Cell Activation without Degranulation through IL1R1 and TLR Signaling
CD16/CD14 Proinflammatory Monocyte Activation
Macrophage M2-Related Phagocytosis
Neutrophil Activation via FCGR3B
Neutrophil Degranulation via FPR1 Signaling
CR3 Mediated Phagocytosis in Neutrophils and Macrophages
Neutrophil Chemotaxis
Neutrophil Activation via Adherence on Endothelial Cells
Vascular Smooth Muscle Cell/Pericyte Migration and Proliferation
Vascular Endothelial Cell Activation by Cytokines
Vascular Endothelial Cell Permeability Activation
Dendritic Spine Morphogenesis and Stabilization
GFs/TNF -> Ion Channels
DRD2 Expression Targets
IL1B Expression Targets -> Nociception
Tight Junction Assembly (Claudins)
Adherens Junction Assembly (Nectin)
Adherens Junction Assembly (Cadherins)
Tight Junction Assembly (JAMs)
Lamellipodia and Filopodia Formation in Cancer
Exocytosis: Vesicle Tethering
Scavenger Receptor OLR1 in Inflammation Related Endothelial Dysfunction
Proteins Involved in Dilated Cardiomyopathy
Proteins Involved in Arterial Hypertension
BMP2 and Non-Canonical WNT Signaling in Pulmonary Artery Endothelial Cells
Endothelial Cell Dysfunction in Pulmonary Hypertension
Smooth Muscle Cell Dysfunction in Pulmonary Hypertension
BMP2 and WNT Signaling in Pulmonary Artery Smooth Muscle Cells
Myocarditis, Acute Viral Overiew
Inflammatory Reaction in Acne Vulgaris
Keratinocyte Proliferation in Acne Vulgaris
Proteins Involved in Melanoma
B-Cell Activation in Systemic Lupus Erythematosus
Neutrophil and Macrophage Function in Systemic Lupus Erythematosus
Vitiligo
Apoptosis of Melanocyte in Vitiligo
Humoral Immunity in Vitiligo
Natural Killer Cell in Diabetes Mellitus Type 1
Macrophage Function in Diabetes Mellitus Type 1
Insulin Resistance in Hepatocytes
beta-Cell Destruction through Cytokines in Diabetes Mellitus
Myocyte Dysfunction in Hypoparathyroidism
Hypoparathyroidism, Primary
Extraocular Muscles Weakness in Myasthenia Gravis
CD8+ T-Cell Response in Celiac Disease
CagA Phosphorylation Independent Signaling
CagA Phosphorylation Dependent Signaling
Dendritic Cell Function in Ulcerative Colitis
Nicotine anti-Inflammatory Effect in Ulcerative Colitis
Antiphospholipid Antibodies in Platelets and Coagulation Cascade
B-Cell Chronic Lymphocytic Leukemia
Mucosa-Associated Lymphoid Tissue (MALT) Lymphoma
Platelet and Coagulation Cascade Activation by Antiphospholipid Antibodies
Eosinophil Activation and Degranulation in Asthma
TSLP Signaling in Bronchial Epithelial Cell in Asthma
Neutrophil Degranulation via FPR1/IL8
Basophil Activation in Asthma
Mast-Cell Activation in Asthma
Mast-Cell Related Chemokines Signaling in Asthma
Antigen-Presenting Cell Role in Asthma
CFTR Facilitates Oxidative Stress in Airway Epithelium in CF
TNF and IL1B Induce Metalloproteinase Synthesis in Osteoarthritis
IL1B Induced Arthralgia
Synovial Fibroblast Activation in Psoriatic Arthritis
Synovial Fibroblast Activation by Citokines in Rheumatoid Arthritis
B-Cells Function in Systemic Scleroderma
CCR5 Signaling in Macrophages
Macrophage Survival through CCR5 and CXCR4 Mediated Signaling
IL1 Receptor Antagonist (IL1RN) Deficiency (DIRA)
Blau Syndrome
IL36 Receptor Antagonist (IL1F5) Deficiency (DITRA)
Familial Cold Autoinflammatory Syndrome 2
Rett Syndrome
IL6 Promotes Inflammation in Muscular Dystrophies
Ca2+ Overload in Muscular Dystrophies
Muscular Dystrophies
Dystrophin Glycoprotein Complex Signaling in Muscular Dystrophies
Proteins Involved in Osteopetrosis
Proteins Involved in Epilepsy
Proteins Involved in Glioblastoma
Proteins Involved in Astrocytoma
Proteins Involved in Glioma
Proteins Involved in Medulloblastoma
Proteins Involved in Neuroblastoma
SOD1 Mutation
Endosomal Trafficking Dysregulation in Amyotrophic Lateral Sclerosis
Microglia and Motor Neuron Interaction Dysregulation
Proteins Involved in Breast Cancer Related to WNT Signaling Pathway
WNT Signaling in Breast Cancer
Angiogenesis in Endometriosis
Subepithelial Fibroblasts in Middle Ear Cholesteatoma
VEGFA in Neovascular Glaucoma
Cytokines Trigger Otitis Media
Alveolar Epithelial Cell Dysfunction in COPD
WNT Signaling in Cystic Kidney Disease
Plasmin Role in Glomerulonephritis
CD157/ITGB2 Signaling in Myeloid Cell
CD38/CD3 -> JUN/FOS/NF-kB Signaling in T-cell Proliferation
CD38/CD19 -> JUN/FOS/NF-kB Signaling in B-cell Proliferation
S100P Expression Target
HMGB1 Expression Targets
TTR Expression Targets
S100A Expression Targets
S100B Expression Targets
ANGPT1 -> CREB/CREBBP Expression Targets
ANGPT2 -> AP-1/CREBBP/MYC Expression Targets
AREG -> NFATC Expression Target
AREG -> CREB/CREBBP Expression Targets
AREG -> NCOR2 Expression Targets
AREG -> AP-1 Expression Targets
Dopamine/Gi Expression Targets
BTC -> NFATC Expression Targets
BTC -> AP-1/ATF/CREB Expression Targets
Frizzled Receptors -> ARRB1/ARRB2 non-Canonical Signaling
ARRB1/ARRB2 non-CanonicalSignaling and HedgehogFamily
CD247 Expression Targets
FCGR3A Expression Targets
CD72 -> NF-kB Expression Targets
CD8 -> NF-kB Expression Targets
CD80 -> NFATC Expression Targets
CD86 -> NFATC Expression Targets
EGF -> AP-1/ATF Expression Targets
EGF -> CREB/CREBBP/ELK/SRF/MYC Expression Targets
EGF -> MEF/MYOD/NFATC Expression Targets
EGF -> TP53 Expression Targets
EGF -> NCOR2 Expression Target
EGFR -> NCOR2 Signaling
EGFR/ERBB3 -> MEF/MYOD/NFATC/MYOG Signaling
EGFR/ERBB2 -> TP53 Signaling
EGFR -> AP-1/ATF2 Signaling
EGFR -> AP-1/CREB/ELK/SRF/MYC Signaling
EREG -> CREB Expression Target
EREG -> AP-1/ATF Expression Targets
Erythropoietin -> AP-1/MYC/CREB Expression Targets
F2 -> AP-1/CREB/ELK/SRF/SP1 Expression Targets
PLG -> AP-1/CREB/ELK/SRF/SP1 Expression Targets
FGF9 -> AP-1/CREB/MYC Expression Targets
FGF10 -> AP-1/CREB/CREBBP/MYC Expression Targets
FGF1 -> AP-1/CREB/ELK/SRF/MYC Expression Targets
FGF1 -> NCOR2 Expression Target
FGF8 -> AP-1/CREB/MYC Expression Targets
FGF18 -> AP-1/CREB Expression Targets
FGF23 -> NCOR2 Expression Targets
FGF2 -> NCOR2 Expression Targets
FGF4 -> AP-1/MYC Expression Targets
FGF7 -> AP-1/CREB/CREBBP/MYC Expression Targets
FGF2 -> AP-1/CREB/CREBBP/ELK/SRF/MYC Expression Targets
FGFR -> AP-1/CREB/CREBBP/ELK/SRF/MYC Signaling
FPR1 -> Cytoskeleton Signaling
FrizzledR -> JUN/PAX2 Signaling
HBEGF -> AP-1/ATF Expression Targets
HBEGF -> TP53 Expression Targets
HBEGF -> MEF/MYOD Expression Target
HBEGF -> CREB/MYC Expression Targets
HGF -> AP-1/CREB/ELK/SRF/MYC Expression Targets
HGFR -> AP-1/CREB/MYC Signaling
EGFR Transactivation in Cancer and Non-Cancer Cells
TAM Receptor Signaling Activation in Cancer
RAS/RAF/MAPK Signaling Activation in Cancer
STAT3 and NFkB Activate Inflammation-Induced Tumorigenesis
RAS/RAF/MAPK Signaling Activation by Blocking of Tumor Suppressors
TGFB Signaling activation by Blocking of Tumor Suppressors
VEGFA Dependent Angiogenesis in Cancer
VEGF Independent Angiogenesis in Cancer
Integrins in Cancer Cell Motility, Invasion and Survival
Proteins with Altered Expression in Cancer Metastases
BSG (CD147) in Cancer Cells Motility, Invasion and Survival
CDH1 Down regulation Promotes Cancer Cell Migration and Metastases
MTOR/TORC in Cancer Cell Motility and Invasion
Hyaluronic Acid, CD44 and HMMR in Cancer Cell Invasion and Survival
CDH2 Activation Promotes Cancer Cell Migration and Survival
TGFB Family in Epithelial to Mesenchymal Transition in Cancer
IGF1 -> MEF/MYOD/MYOG Expression Targets
IGF2/MEF/MYOD Expression Targets
Insulin -> MEF/MYOD Expression Targets
AGER -> CREB/SP1 Signaling
FcIgER -> ELK-SRF Signaling
IGF1R -> MEF/MYOD/MYOG Signaling
FibronectinR -> NF-kB Signaling
FibronectinR -> AP-1/ELK/SRF/SREBF Signaling
Fibronectin Expression Targets
CTGF -> AP-1/CREB/MYC Expression Targets
CTGF -> NCOR2 Expression Target
IL1R -> STAT3 Signaling
IL1R -> NF-kB Signaling
IL16-> ATF/CREB/CREBBP Expression Target
LPA Expression Targets
NRG1 -> MEF/MYOD Expression Targets
NRG1 -> CREB/CREBBP/ELK/SRF/MYC Expression Targets
NRG1 -> TP53 Expression Target
NRG1 -> AP-1/ATF Expression Targets
PDGFB -> AP-1/CREB/MYC Expression Target
PDGFC -> CREB Expression Target
PDGFD -> AP-1 Expression Targets
PDGF -> AP-1/CREB/CREBBP/MYC Expression Targets
KIT -> MITF Signaling
PDGFR -> AP-1/MYC Signaling
AVP/Gs -> CREB/ELK/SRF/AP-1/EGR Expression Targets
EDN1 Expression Targets
AVP/Gs -> MEF/MYOD/NFATC/MYOG Expression Targets
AVP/Gq -> MEF/MYOD/NFATC/MYOG Expression Targets
EDN3 Expression Targets
AVP/Gq -> CREB/ELK/SRF/AP-1/EGR Expression Targets
PDCD1 -> ATF/CREB/CREBBP Expression Targets
AngiopoietinR -> AP-1 Signaling
EphrinB -> Cytoskeleton Signaling
GDNF -> HSF1 Signaling
EphrinB -> MAPK/JUN/FOS Signaling
NTRK -> AP-1/CREB/ELK/SRF/MYC/SMAD3/TP53 Signaling
GAS6 -> AP-1/CREB Expression Targets
FIGF -> AP-1 Expression Target
FIGF -> NCOR2 Expression Target
KITLG -> AP-1/CREB/CREBBP/MYC Expression Targets
GDNF -> HSF1 Expression Targets
CSF1 -> AP-1/CREB/CREBBP/MYC Expression Targets
PGF -> AP-1/CREB/CREBBP/MYC Expression Targets
FLT3LG -> AP-1/CREB/CREBBP Expression Targets
Lysophosphatidic Acid/LPARs Signaling
JNK/MAPK Signaling
MERTK Signaling
Ras Signaling
TGF-beta Signaling
Ras-GAP Regulation Signaling
P38 MAPK/MAPK14 Signaling
AXL Receptor Tyrosine Kinase Signaling
PI3K/RAC1 Signaling
VEGF Signaling
EGFR Signaling
WNT Planar Cell Polarity (PCP) non-Canonical Signaling
ERK/MAPK Canonical Signaling
TCR -> CREB/CREBBP/ATF Expression Targets
T-Cell Receptor -> ATF/CREB Signaling
TGFA -> TP53 Expression Targets
TGFA -> MEF/MYOD/NFATC Expression Targets
TGFA/AP-1/ATF Expression Targets
TGFA -> CREB/CREBBP/ELK-SRF/MYC Expression Targets
Thrombopoietin -> AP-1/CREB/CREBBP/MYC Expression Targets
TLR1 -> 2/6 Expression Targets
IL1B Expression Targets
IL1A Expression Targets
TLR1/2/6 -> NF-kB Signaling
ROS in Triggering Vascular Inflammation
ROS and RNS in Vasoconstriction and Vasodilation Regulation
ROS in Angiotensin Mediated Cardiovascular Remodeling and Hypertrophy
VEGFA -> AP-1/CREBBP/MYC Expression Targets
VEGFA -> NCOR2 Expression Target
VEGFR -> AP-1/CREB/MYC Signaling
WNT1 Expression Targets
WNT3A Expression Targets
WNT4 Expression Targets
WNT5A Expression Targets
WNT7A Expression Targets
ace2
Model of PPARG signaling in psoriasis
sars-cov no binding
New Pathway
2_The role of endothelial cells in pyelonephritis
3_Enhanced angiogenesis in endometriosis
1_Disruption of luteinizing hormone and follicle-stimulating hormone secretion in PCOS
3_Arterial wall inflammation and calcification in atherosclerosis
2_Oxidized LDL causes endothelial dysfunction in atherosclerosis
1_Endothelial cells stimulate vasoconstriction and thrombosis in pulmonary hypertension
1_Cigarette smoke causes dysfunction and production of inflammatory mediators in alveolar epithelial cells
1_Th2 cell response in asthma
2_1_Eosinophilia and neutrophilia in asthma: eosinophil migration and activation
2_2_Eosinophilia and neutrophilia in asthma: eosinophil apoptosis
4_2_Airway smooth muscle cells proliferation and airway tissue remodeling
2_Intestine epithelial cells drive immunological responses in ulcerative colitis
4_1_Polymorphisms associated with inflammatory bowel diseases
2_CD8+ T-cell response and mucosal damage in celiac disease
2_Mutations in SOD1 and associated proteins cause motor neuron death in familial ALS
2_1_General pathways of thyroid hormone signaling

Group other partners for SARS

MedScan ID 5879

LocusLink ID 5879
19353
363875
100781
171377
52352

Alias p21-Rac1
ras-related C3 botulinum toxin substrate 1 isoform Rac1
rho family, small GTP binding Rac
p21-Rac I
migration-inducing protein 5
cell migration-inducing gene 5 protein
rac1 GTP-binding protein
ras-related C3 botulinum toxin substrate 1 isoform Rac1b
ras-related C3 botulinum toxin substrate 1 isoform Rac I
rho family, small GTP binding protein Rac1
rac1c
ras-related C3 botulinum toxin substrate I
MGC111543
GTP-binding protein rac1
small gtp binding protein rac1
RAS-related C3 botulinum substrate 1
migration-inducing protein V
MRD48
Rac(V12)
RAS-related C3 botulinum substrate I
Rac1B
Rac family small GTPase 1
Rac1
D5Ertd559e
rho family, small GTP binding protein Rac I
DNA segment, Chr 5, ERATO Doi 559, expressed
LOC136000
OTTMUSP00000022620
rac1 GTP binding protein
Ras-like protein TC25
ras-related C3 botulinum toxin substrate 1 (rho family small GTP binding protein Rac1)
ras-related C3 botulinum toxin substrate 1
LOC155330
GTP-binding protein rac I
Rac I
AL023026
TC-25
RAC1_HUMAN
MIG5
Rac-1
ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
TC25
migration-inducing gene 5
Ras-like protein TC25
expressed sequence AL023026
isoform rac1b

EC Number 3.6.5.2

GO ID 0051117
0005525
0003924
0017137
0051022
0019899
0042826
0019901
0044877
0031996
0038095
0038096
0016601
0007266
0031295
0060071
0030036
0030041
0009653
0007596
0045453
0007155
0016477
0048870
0030031
0008283
0007160
0071260
0048013
0048012
0006954
0035556
0030032
0051668
0002551
0008045
0032707
0048261
0001764
0043312
0045740
0035025
0010811
0051894
0035774
0010592
0031116
0090023
0051897
0001934
0051496
1900026
0030334
0008361
0050690
0010310
0010591
1902622
0045428
0060263
0051056
0051492
0009611
0097178
0031529
0071526
0034446
0048010
0000139
0005884
0042995
0005737
0036464
0031410
0005829
0043197
0005789
0070062
0101003
0005925
0098978
0030027
0042470
0016020
0005886
0098794
0055038
0032587
0030667
0005802
0030742
0000166
0007186
0007015
0048532
0002093
0007411
0045216
0021894
0021799
0006935
0090103
0007010
0016358
0048813
0071542
0021831
0006897
0043652
0003382
0030900
0048873
0006972
1904948
0048812
0035567
0006911
0030838
0060999
0043552
0072659
0022604
0010762
0014041
0048168
0007264
0051932
0031901
0019897
0060091
0005634
0000242
0001891
0008152
0006928
0030168
0043065
0015031
0016023
0005622
0097190
0045087
0048011
0016032
0006184
0006915
0008624
0030155
0005624
0023034
0005515
0050775

KEGG ID hsa:5879
mmu:19353
rno:363875

MedLine Reference 11756405
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17653061
17804720
7561098
15721239
15723051
17085464
17183546
17207463
17515454
17515837
17687038

Organism Homo sapiens {Organism urn:agi-taxid:9606}
Mus musculus {Organism urn:agi-taxid:10090}
Rattus norvegicus {Organism urn:agi-taxid:10116}
Homo sapiens
Mus musculus
Rattus norvegicus

Mouse chromosome position 5 82.22 cM
5 82.0 cM

OMIM ID 602048
617751

Rat chromosome position 12p11

Hugo ID 9801
HGNC:9801

Human chromosome position 7p22.1
7p22

Swiss-Prot Accession A4D2P1
P63000
A4D2P0
P63000.1
Q3TLP8
K7Q7T7
P63001
P63001.1
Q6RUV5
Q6RUV5.1
O95501
P15154
Q3Y4D3
Q5JAA8
Q9BTB4
Q59FQ0
Q8BPG5
Q8C4N8
Q9D859
Q923X0
AAB22206
RAC1_HUMAN
RAC1_MOUSE
RAC1_RAT
A4D2P0_HUMAN
A4D2P1_HUMAN

PIR ID A34788
A60347

GenBank ID NC_000007
NM_018890
NP_061485
NM_006908
NP_008839
NG_029431
AC009412
AAS07511
AAS07512
AJ132695
CAA10733
CAB53579
AL833528
CH236963
EAL23718
EAL23719
EAL23720
CH878731
EAW55039
EAW55040
EAW55041
EAW55042
EAW55043
EAW55044
CS026591
CAI61762
CS026817
CAI61874
DQ165078
AAZ80485
AB209410
BAD92647
AB451238
BAG70052
AB451363
BAG70177
AF136373
AAD30547
AF498964
AAM21111
AJ132694
CAA10732
AK054993
BAG51447
AK122742
AK291806
BAF84495
AK291815
BAF84504
AY279384
AAQ16632
BC004247
AAH04247
BC050687
AAH50687
BC107748
AAI07749
BG437715
BQ689587
BT007121
AAP35785
D25274
M29870
AAA36537
M31467
AAA36544
P63000
NC_000071
XM_006504667
XP_006504730
NM_009007
NP_033033
NM_001347530
AC163995
AC175091
AC217112
CH466529
EDL19046
EDL19047
EDL19048
AK008435
BAB25667
AK009017
BAB26027
AK011072
BAB69451
AK034601
BAC28767
AK047969
BAC33203
AK076023
BAC36128
AK081613
BAC38272
AK088825
BAC40596
AK166383
BAE38744
AK181319
AK182603
AK184868
AK186906
AK190884
AK199407
AK209867
AK211591
AK216533
AK219413
BC003828
AAH03828
BC051053
AAH51053
BQ444803
CO425367
CX242948
CX566679
JN971018
AFR23587
U25107
AAB42023
X57277
CAA40545
P63001
NC_005111
XM_008768986
XP_008767208
NM_134366
NP_599193
AC_000080
AABR07035397
AAHX01071257
CH474012
EDL89664
EDL89665
EDL89666
AF385833
AAK66567
AY491395
AAR84574
FQ209708
FQ230945
Q6RUV5
NC_018918
AMYH02015172
AMYH02015173
AAB22206
EU831965
ACE87406
EU832058
ACE86720
EU832640
ACE87731
EU832717
ACE87049
AC_000027
AAHY01050472
AAHY01050473
AC_000139
ABBA01056484
ABBA01056485
AC_000068
AACC02000121
AABR06070505
NT_007819
NT_079592
NW_923217
NW_001839003
AC_000050
CR591797
CR612844
CR621312
CR624356
CR624866
Q59FQ0
NT_081055
NW_001030796
Q3TLP8
Q8BPG5
Q8C4N8
Q9D859
NW_001084671
NW_047368
Q923X0
AK195884
NM_198829
NP_942126
AK193118
BG064327
Y12699
U80083
Q5JAA8
AL023026
U77544
U85236
AAB36753
AAC50998
U91215
BG088950
CAA73231
AAC51432
AAB58438
NW_000241
BG076502
14532301
40354188
51701705
81902670
123786781
12842616
12843555
13277918
15919905
1816498
26330057
26339064
26344958
26349265
26353932
29835222
51702788
53886
74147756
81874558
81881587
81898825
AU022720
119575441
119575442
119575444
119575446
13279011
1685223
1791009
190824
190875
20379102
2145168
2239837
2266631
249582
29792302
30583081
33358321
41473432
41473433
4454211
4836769
51094459
51094460
51094461
51702787
60496663
60496888
73672821
74741595
78070394
8574038
8574039
P15154
119575443
119575445
62088400
74707268
148687099
148687100
148687101
149034944
149034945
149034946

Swiss-Prot ID RAC1_HUMAN
RAC1_MOUSE
RAC1_RAT
A4D2P1_HUMAN
A4D2P0_HUMAN

Cell Localization Cell membrane
Melanosome
Cytoplasm
Cell projection
Lamellipodium
Dendrite
Plasma membrane

Ensembl ID ENSG00000136238
ENSP00000258737.7
ENST00000348035.9
ENSP00000348461.4
ENST00000356142.4
ENSMUSG00000001847
ENSMUSP00000079380.7
ENSMUST00000080537.13
ENSMUSP00000098058.3
ENSMUST00000100489.3
ENSRNOG00000001068
ENSRNOP00000001417.3
ENSRNOT00000001417.5
ENSRNOP00000071616.1
ENSRNOT00000087094.1
ENSP00000258737
ENST00000348035
ENSP00000348461
ENST00000356142
ENSMUSP00000079380
ENSMUST00000080537
ENSMUSP00000098058
ENSMUST00000100489
ENSRNOP00000001417
ENSRNOT00000001417
ENSRNOP00000071616
ENSRNOT00000087094

MGI ID MGI:97845
97845
2141016
1261850

RGD ID 619755

Unigene ID Hs.413812
Mm.292510
Mm.469963
Mm.475073
Rn.29157
Mm.342177
Mm.466548
Mm.74208
Hs.632900
Hs.633454
Hs.551925
Mm.432479

Homologene ID 69035

IPI ID IPI00010271
IPI00219675
IPI00422092
IPI00761613
IPI00555566
IPI00394837
IPI00127408
IPI00780227

Homo sapiens Chromosome position 7p22

Ensembl Transcript ID ENST00000348035
ENST00000356142
ENST00000396729

ENSEMBL ENSG00000136238

FunctionalClass GTP binding
GTPase
protein binding
nucleotide binding
GTP-dependent protein binding

Mus musculus Chromosome position 5 82.0 cM
5

ProteinAtlas SubcellularLocation Main location: Nucleus;Cytoplasm; Other location: Nucleoli; Expression type: Staining; Reliability: Uncertain

Rattus norvegicus Chromosome position 12p11

Ensembl Gene ID ENSG00000136238

ProteinAtlas NormalTissue Tissue: adrenal gland; Cell type: glandular cells; Level: Moderate; Expression type: Staining; Reliability: Supportive
Tissue: appendix; Cell type: glandular cells; Level: Moderate; Expression type: Staining; Reliability: Supportive
Tissue: appendix; Cell type: lymphoid tissue; Level: Negative; Expression type: Staining; Reliability: Supportive
Tissue: bone marrow; Cell type: hematopoietic cells; Level: Moderate; Expression type: Staining; Reliability: Supportive
Tissue: breast; Cell type: glandular cells; Level: Negative; Expression type: Staining; Reliability: Supportive
Tissue: bronchus; Cell type: respiratory epithelial cells; Level: Weak; Expression type: Staining; Reliability: Supportive
Tissue: cerebellum; Cell type: cells in granular layer; Level: Negative; Expression type: Staining; Reliability: Supportive
Tissue: cerebellum; Cell type: cells in molecular layer; Level: Negative; Expression type: Staining; Reliability: Supportive
Tissue: cerebellum; Cell type: Purkinje cells; Level: Weak; Expression type: Staining; Reliability: Supportive
Tissue: cerebral cortex; Cell type: glial cells; Level: Negative; Expression type: Staining; Reliability: Supportive
Tissue: cerebral cortex; Cell type: neuronal cells; Level: Negative; Expression type: Staining; Reliability: Supportive
Tissue: cervix, uterine; Cell type: glandular cells; Level: Negative; Expression type: Staining; Reliability: Supportive
Tissue: cervix, uterine; Cell type: squamous epithelial cells; Level: Weak; Expression type: Staining; Reliability: Supportive
Tissue: colon; Cell type: glandular cells; Level: Strong; Expression type: Staining; Reliability: Supportive
Tissue: duodenum; Cell type: glandular cells; Level: Moderate; Expression type: Staining; Reliability: Supportive
Tissue: epididymis; Cell type: glandular cells; Level: Negative; Expression type: Staining; Reliability: Supportive
Tissue: esophagus; Cell type: squamous epithelial cells; Level: Negative; Expression type: Staining; Reliability: Supportive
Tissue: fallopian tube; Cell type: glandular cells; Level: Moderate; Expression type: Staining; Reliability: Supportive
Tissue: gall bladder; Cell type: glandular cells; Level: Moderate; Expression type: Staining; Reliability: Supportive
Tissue: heart muscle; Cell type: myocytes; Level: Negative; Expression type: Staining; Reliability: Supportive
Tissue: hippocampus; Cell type: glial cells; Level: Negative; Expression type: Staining; Reliability: Supportive
Tissue: hippocampus; Cell type: neuronal cells; Level: Negative; Expression type: Staining; Reliability: Supportive
Tissue: kidney; Cell type: cells in glomeruli; Level: Negative; Expression type: Staining; Reliability: Supportive
Tissue: kidney; Cell type: cells in tubules; Level: Weak; Expression type: Staining; Reliability: Supportive
Tissue: lateral ventricle; Cell type: glial cells; Level: Negative; Expression type: Staining; Reliability: Supportive
Tissue: lateral ventricle; Cell type: neuronal cells; Level: Negative; Expression type: Staining; Reliability: Supportive
Tissue: liver; Cell type: bile duct cells; Level: Negative; Expression type: Staining; Reliability: Supportive
Tissue: liver; Cell type: hepatocytes; Level: Negative; Expression type: Staining; Reliability: Supportive
Tissue: lung; Cell type: macrophages; Level: Negative; Expression type: Staining; Reliability: Supportive
Tissue: lung; Cell type: pneumocytes; Level: Moderate; Expression type: Staining; Reliability: Supportive
Tissue: lymph node; Cell type: germinal center cells; Level: Negative; Expression type: Staining; Reliability: Supportive
Tissue: lymph node; Cell type: non-germinal center cells; Level: Negative; Expression type: Staining; Reliability: Supportive
Tissue: nasopharynx; Cell type: respiratory epithelial cells; Level: Moderate; Expression type: Staining; Reliability: Supportive
Tissue: oral mucosa; Cell type: squamous epithelial cells; Level: Negative; Expression type: Staining; Reliability: Supportive
Tissue: ovary; Cell type: ovarian stroma cells; Level: Negative; Expression type: Staining; Reliability: Supportive
Tissue: pancreas; Cell type: exocrine glandular cells; Level: Weak; Expression type: Staining; Reliability: Supportive
Tissue: pancreas; Cell type: islets of Langerhans; Level: Negative; Expression type: Staining; Reliability: Supportive
Tissue: parathyroid gland; Cell type: glandular cells; Level: Negative; Expression type: Staining; Reliability: Supportive
Tissue: placenta; Cell type: decidual cells; Level: Moderate; Expression type: Staining; Reliability: Supportive
Tissue: placenta; Cell type: trophoblastic cells; Level: Negative; Expression type: Staining; Reliability: Supportive
Tissue: prostate; Cell type: glandular cells; Level: Weak; Expression type: Staining; Reliability: Supportive
Tissue: rectum; Cell type: glandular cells; Level: Moderate; Expression type: Staining; Reliability: Supportive
Tissue: salivary gland; Cell type: glandular cells; Level: Negative; Expression type: Staining; Reliability: Supportive
Tissue: seminal vesicle; Cell type: glandular cells; Level: Negative; Expression type: Staining; Reliability: Supportive
Tissue: skeletal muscle; Cell type: myocytes; Level: Weak; Expression type: Staining; Reliability: Supportive
Tissue: skin; Cell type: epidermal cells; Level: Weak; Expression type: Staining; Reliability: Supportive
Tissue: small intestine; Cell type: glandular cells; Level: Moderate; Expression type: Staining; Reliability: Supportive
Tissue: smooth muscle; Cell type: smooth muscle cells; Level: Negative; Expression type: Staining; Reliability: Supportive
Tissue: spleen; Cell type: cells in red pulp; Level: Negative; Expression type: Staining; Reliability: Supportive
Tissue: spleen; Cell type: cells in white pulp; Level: Negative; Expression type: Staining; Reliability: Supportive
Tissue: stomach, lower; Cell type: glandular cells; Level: Weak; Expression type: Staining; Reliability: Supportive
Tissue: stomach, upper; Cell type: glandular cells; Level: Moderate; Expression type: Staining; Reliability: Supportive
Tissue: testis; Cell type: cells in seminiferus ducts; Level: Negative; Expression type: Staining; Reliability: Supportive
Tissue: testis; Cell type: Leydig cells; Level: Weak; Expression type: Staining; Reliability: Supportive
Tissue: thyroid gland; Cell type: glandular cells; Level: Negative; Expression type: Staining; Reliability: Supportive
Tissue: tonsil; Cell type: germinal center cells; Level: Negative; Expression type: Staining; Reliability: Supportive
Tissue: tonsil; Cell type: non-germinal center cells; Level: Negative; Expression type: Staining; Reliability: Supportive
Tissue: tonsil; Cell type: squamous epithelial cells; Level: Moderate; Expression type: Staining; Reliability: Supportive
Tissue: urinary bladder; Cell type: urothelial cells; Level: Moderate; Expression type: Staining; Reliability: Supportive
Tissue: uterus, post-menopause; Cell type: cells in endometrial stroma; Level: Negative; Expression type: Staining; Reliability: Supportive
Tissue: uterus, post-menopause; Cell type: glandular cells; Level: Weak; Expression type: Staining; Reliability: Supportive
Tissue: uterus, pre-menopause; Cell type: cells in endometrial stroma; Level: Negative; Expression type: Staining; Reliability: Supportive
Tissue: uterus, pre-menopause; Cell type: glandular cells; Level: Moderate; Expression type: Staining; Reliability: Supportive
Tissue: vagina; Cell type: squamous epithelial cells; Level: Negative; Expression type: Staining; Reliability: Supportive
Tissue: vulva/anal skin; Cell type: epidermal cells; Level: Negative; Expression type: Staining; Reliability: Supportive

LocatorString digtext:C:\Users\Ariadne\Customers\Elan\Elan weekly report from literature condensed.txt