Protein IL1A

URN urn:agi-llid:3552
Total Entities 0
Connectivity 5556
Name IL1A
Description interleukin 1, alpha
Notes The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis. This cytokine is produced by monocytes and macrophages as a proprotein, which is proteolytically processed and released in response to cell injury, and thus induces apoptosis. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. It has been suggested that the polymorphism of these genes is associated with rheumatoid arthritis and Alzheimer's disease. [provided by RefSeq, Jul 2008]
Primary Cell Localization Extracellular
Class Ligand
ObjectType Protein

Pathway Plasmin Effects in Inflammation
Bradykinin Effects in Inflammation
Toll-like Receptors in Sterile Inflammation
Toll-like Receptor Independent Sterile Inflammation
Hypothalamic-Pituitary-Adrenal Axis in Acute Phase Response
Histamine Effects in Inflammation
Eosinophil Activation
Mast-Cell Activation without Degranulation
Mast-Cells De Novo Synthesized Mediators via IgE Independent Signaling
Mast-Cell Activation without Degranulation through IL1R1 and TLR Signaling
Negative Acute Phase Proteins Synthesis
Positive Acute Phase Proteins Synthesis
Proteins Involved in Atherosclerosis
Proteins with Altered Expression in Acne Vulgaris
Proteins Involved in Acne Vulgaris
Keratinocyte Proliferation in Acne Vulgaris
Apoptotic Keratinocytes Clearance Recession in Systemic Lupus Erythematosus
Dendritic Cell Activation in Systemic Lupus Erythematosis
Tubular Cell Dysfunction in Progressive Diabetic Nephropathy
Endothelial Cell Dysfunction in Early Diabetic Nephropathy
Proteins Involved in Diabetic Nephropathy
Microangiopathy in Diabetic Neuropathy
Hepatic Stellate Cells in non-Alcoholic Fatty Liver Disease
Proteins Involved in non-Alcoholic Fatty Liver Disease
Proteins Involved in Graves Disease
Graves Ophthalmopathy
Thymic Follicular Hyperplasia
Proteins Involved in Obesity
Antiphospholipid Antibodies in Endothelial Cell
TNFR/NF-kB Classical Pathway in Multiple Myeloma Plasma Cells
TNFR/NF-kB Alternative Pathway in Multiple Myeloma Plasma Cells
Antiphospholipid Antibodies and Endothelial Cell Interaction
Proteins Involved in Osteoarthritis
Osteoclast Activation in Psoriatic Arthritis
Proteins Involved in Rheumatoid Arthritis
Autocrine Cytokine/Chemokine Loops in Systemic Scleroderma
Genes with Mutations Associated with Systemic Scleroderma
Proteins Involved in Systemic Scleroderma
Proteins Involved in Periodontitis
IL1 Receptor Antagonist (IL1RN) Deficiency (DIRA)
IL36 Receptor Antagonist (IL1F5) Deficiency (DITRA)
Proteins with Altered Expression in Psoriatic Arthritis
Microglia Activation in Alzheimer's Disease
Proteins Involved in Glioblastoma
Proteins Involved in Glioma
Microglia Activation in Parkinson's Disease
MBP/MOG/PLP in Immune System Activation
Proteins Involved in Endometriosis
Proteins Involved in Spontaneous Abortion
Proteins Involved in Cholesteatoma
Subepithelial Fibroblasts in Middle Ear Cholesteatoma
HPV E6 and E7 Induced Disruption of TNFR/NF-kB Signaling in Keratinocytes
Cytokines Trigger Otitis Media
Alveolar Macrophage Negative Regulation Declined in COPD
Alveolar Macrophages Dysfunction in COPD
Plasmin Role in Glomerulonephritis
Endothelial Cell Dysfunction in Glomerulonephritis
AREG -> AP-1 Expression Targets
Noradrenaline/Gs Expression Targets
Noreadrenaline/Gq Expression Targets
CXCL12 Expression Targets
EGF -> CTNN Expression Targets
EGF -> AP-1/ATF Expression Targets
EGF -> CREB/CREBBP/ELK/SRF/MYC Expression Targets
EGF -> MEF/MYOD/NFATC Expression Targets
EGF -> STAT Expression Targets
F2 -> AP-1/CREB/ELK/SRF/SP1 Expression Targets
F2 -> STAT1/NF-kB Expression Targets
PLG -> AP-1/CREB/ELK/SRF/SP1 Expression Targets
PLG -> STAT1/NF-kB Expression Targets
GH1/GHR -> NF-kB/ELK/SRF/MYC Expression Targets
GH1/GHR -> STAT Expression Targets
GH1/PRLR Expression Targets
NFKB Canonical Signaling Activation in Cancer
NFKB Signaling Activation by Blocking of Tumor Suppressors
VEGFA Dependent Angiogenesis in Cancer
EGFR -> Expression Targets in Skin
IFNG/IFNR Expression Targets
IL1R -> STAT3 Signaling
IL1R -> NF-kB Signaling
IL2 Expression Targets
PAF/Gq -> AP-1/ATF1/CREB/ERK/SRF Expression Targets
CD Markers -> Expression Targets in Lymphoid System and Blood
PRL/PRLR Expression Targets
PRL/GHR -> STAT Expression Targets
PRL/GHR -> NF/kB/ELK/SRF/MYC Expression Targets
KITLG -> STAT Expression Targets
KITLG -> AP-1/CREB/CREBBP/MYC Expression Targets
PAF Expression Targets
NF-kB Canonical Signaling
TGFA -> STAT Expression Targets
TGFA -> CTNNB/CTNND Expression Targets
TGFA/AP-1/ATF Expression Targets
TGFA -> CREB/CREBBP/ELK-SRF/MYC Expression Targets
FASLG Expression Targets
TNF -> NF-kB Expression Targets
TNFSF10 Expression Targets
TNF -> AP-1 Expression Targets
CD72 -> AP-1 Expression Targets
IL1B -> PGE2 Expression Targets
IL1B Expression Targets
TLR4 -> NF-kB/IRF Expression Targets
IL1A Expression Targets
prarg negative regulators, ps-positive
prarg neg,ukn expres targets, ps-positive
PPARG negative regulators
PPARG negative targets
pparg expr target_regulators
Neighbors of disease exacerbation
Neighbors of tumor progression
Neighbors of cancer progression
Neighbors of inflammatory status
Neighbors of overall survival
Neighbors of disease severity
Neighbors of tumor size
Neighbors of mortality
Neighbors of survival rate
Neighbors of infarct size
Neighbors of survival time
Neighbors of functional recovery
Neighbors of bacterial load
Neighbors of cancer survival
Neighbors of therapeutic efficacy
Neighbors of lethality
Neighbors of tumor regression
Neighbors of tumor response
Neighbors of treatment outcome
Neighbors of bone mass
Neighbors of body weight
Neighbors of body weight gain
Neighbors of cardiovascular risk
Neighbors of tumor promotion
Neighbors of neutrophil count
Neighbors of morbidity
Neighbors of bone mineral density
Neighbors of radioresistance
Neighbors of cell density
Neighbors of viral load
Neighbors of blood pressure
Neighbors of leukocyte count
Neighbors of vascular leakage
Neighbors of muscle mass
Neighbors of cancer incidence
Neighbors of blood glucose
Neighbors of osteoclast number
Neighbors of energy expenditure
Neighbors of breast cancer risk
Neighbors of cell permeability
Neighbors of fertility
Neighbors of lymphocyte count
Neighbors of monocyte count
Neighbors of metabolic response
Neighbors of bone volume
Neighbors of fibroblast phenotype
Neighbors of fractional shortening
Neighbors of disease exacerbation
Neighbors of tumor progression
Neighbors of cancer progression
Neighbors of inflammatory status
Neighbors of overall survival
Neighbors of disease severity
Neighbors of tumor size
Neighbors of mortality
Neighbors of survival rate
Neighbors of infarct size
Neighbors of survival time
Neighbors of functional recovery
Neighbors of bacterial load
Neighbors of cancer survival
Neighbors of therapeutic efficacy
Neighbors of lethality
Neighbors of tumor regression
Neighbors of tumor response
Neighbors of treatment outcome
Neighbors of bone mass
Neighbors of body weight
Neighbors of body weight gain
Neighbors of cardiovascular risk
Neighbors of tumor promotion
Neighbors of neutrophil count
Neighbors of morbidity
Neighbors of bone mineral density
Neighbors of radioresistance
Neighbors of cell density
Neighbors of viral load
Neighbors of blood pressure
Neighbors of leukocyte count
Neighbors of vascular leakage
Neighbors of muscle mass
Neighbors of cancer incidence
Neighbors of blood glucose
Neighbors of osteoclast number
Neighbors of energy expenditure
Neighbors of breast cancer risk
Neighbors of cell permeability
Neighbors of fertility
Neighbors of lymphocyte count
Neighbors of monocyte count
Neighbors of metabolic response
Neighbors of bone volume
Neighbors of fibroblast phenotype
Neighbors of fractional shortening
Neighbors of cell development
Neighbors of immune response
Neighbors of cell population
Neighbors of T-cell development
Neighbors of inflammatory response
Neighbors of wound healing
Neighbors of angiogenesis
Neighbors of innate immune response
Neighbors of cell function
Neighbors of macrophage activation
Neighbors of cell formation
Neighbors of adaptive immune response
Neighbors of osteoclast development
Neighbors of epithelial to mesenchymal transition
Neighbors of immunity
Neighbors of cell proliferative response
Neighbors of chemotaxis
Neighbors of dendritic cell differentiation
Neighbors of cell survival
Neighbors of osteoclast differentiation
Neighbors of cell phenotype
Neighbors of T-cell proliferation
Neighbors of tissue remodeling
Neighbors of cell adhesion
Neighbors of T-cell activation
Neighbors of endothelial cell proliferation
Neighbors of fibrogenesis
Neighbors of tumor growth
Neighbors of dendritic cell development
Neighbors of tissue repair
Neighbors of cell count
Neighbors of cell infiltration
Neighbors of cell interaction
Neighbors of SMC proliferation
Neighbors of lumen formation
Neighbors of endothelial cell migration
Neighbors of adipogenesis
Neighbors of lipid storage
Neighbors of cell damage
Neighbors of pregnancy
Neighbors of monocyte differentiation
Neighbors of aging
Neighbors of cell motility
Neighbors of bone resorption
Neighbors of monocyte migration
Neighbors of fibroblast proliferation
Neighbors of adipocyte differentiation
Neighbors of macrophage migration
Neighbors of microglial activation
Neighbors of neutrophil recruitment
Neighbors of regeneration
Neighbors of cell migration
Neighbors of cancer growth
Neighbors of stem cell proliferation
Neighbors of smooth muscle cell migration
Neighbors of hepatic regeneration
Neighbors of transendothelial migration
Neighbors of phagocytosis
Neighbors of immune system activation
Neighbors of leukocyte migration
Neighbors of leukocyte recruitment
Neighbors of osteoclast formation
Neighbors of monocyte recruitment
Neighbors of cell invasion
Neighbors of heart function
Neighbors of hemopoiesis
Neighbors of bone remodeling
Neighbors of ossification
Neighbors of T-cell function
Neighbors of immune system function
Neighbors of lung development
Neighbors of autophagy
Neighbors of monocyte adhesion
Neighbors of transcription activation
Neighbors of senescence
Neighbors of T-cell response
Neighbors of tumor immunity
Neighbors of hepatocyte proliferation
Neighbors of cell transdifferentiation
Neighbors of neuroprotection
Neighbors of endothelial cell function
Neighbors of neuronal death
Neighbors of cell growth
Neighbors of ROS generation
Neighbors of epithelial cell proliferation
Neighbors of first trimester pregnancy
Neighbors of cancer cell growth
Neighbors of sensitization
Neighbors of hemato-encephalic barrier
Neighbors of cellular immune response
Neighbors of cellular senescence
Neighbors of colony formation
Neighbors of macrophage differentiation
Neighbors of cell differentiation
Neighbors of keratinocyte proliferation
Neighbors of life span
Neighbors of cell homeostasis
Neighbors of psoriasis
Neighbors of inflammatory disease
Neighbors of rheumatoid arthritis
Neighbors of atherosclerosis
Neighbors of fibrosis
Neighbors of colitis
Neighbors of arthritis
Neighbors of inflammatory bowel disease
Neighbors of injury
Neighbors of atherogenesis
Neighbors of metastasis
Neighbors of carcinogenesis
Neighbors of chronic inflammation
Neighbors of inflammation
Neighbors of tumor microenvironment
Neighbors of pathological angiogenesis
Neighbors of obesity
Neighbors of vascular disease
Neighbors of diabetes mellitus
Neighbors of asthma
Neighbors of pneumonia
Neighbors of hyperplasia
Neighbors of osteoarthritis
Neighbors of chronic obstructive pulmonary disease
Neighbors of myocardial infarction
Neighbors of leukocyte infiltration
Neighbors of reperfusion injury
Neighbors of airway inflammation
Neighbors of hepatitis
Neighbors of insulin resistance
Neighbors of infection
Neighbors of vascular injury
Neighbors of renal injury
Neighbors of liver injury
Neighbors of neuroinflammation
Neighbors of sepsis
Neighbors of death
Neighbors of type 1 diabetes
Neighbors of encephalomyelitis
Neighbors of autoimmune disease
Neighbors of ischemic stroke
Neighbors of dermatitis
Neighbors of neutrophil infiltration
Neighbors of heart disease
Neighbors of diabetic nephropathy
Neighbors of lung injury
Neighbors of immunopathology
Neighbors of systemic sclerosis
Neighbors of hepatocellular carcinoma
Neighbors of autoimmunity
Neighbors of acute lung injury
Neighbors of gastric cancer
Neighbors of experimental autoimmune encephalomyelitis
Neighbors of colorectal cancer
Neighbors of cardiac remodeling
Neighbors of breast cancer
Neighbors of ischemia
Neighbors of melanoma
Neighbors of collagen-induced arthritis
Neighbors of cartilage degeneration
Neighbors of neoplasm invasion
Neighbors of kidney disease
Neighbors of heart failure
Neighbors of lung disease
Neighbors of pulmonary fibrosis
Neighbors of stroke
Neighbors of cancer
Neighbors of type 2 diabetes
Neighbors of neoplasm
Neighbors of endometriosis
Neighbors of vasculitis
Neighbors of atrophy
Neighbors of respiratory hypersensitivity
Neighbors of synovitis
Neighbors of coronary artery disease
Neighbors of rupture
Neighbors of endothelial cell dysfunction
Neighbors of liver disease
Neighbors of prostate cancer
Neighbors of hypertrophy
Neighbors of osteolysis
Neighbors of ovarian cancer
Neighbors of pancreatic cancer
Neighbors of hypertension
Neighbors of intimal hyperplasia
Neighbors of allograft rejection
Neighbors of proteinuria
Neighbors of epithelial cell
Neighbors of keratinocyte
Neighbors of vascular smooth muscle cell
Neighbors of umbilical vein endothelial cell
Neighbors of monocyte
Neighbors of alveolar macrophage
Neighbors of synoviocyte
Neighbors of macrophage
Neighbors of adipocyte
Neighbors of activated monocyte
Neighbors of fibroblast
Neighbors of airway epithelial cell
Neighbors of PBMC
Neighbors of stromal cell
Neighbors of osteoblast
Neighbors of pneumocyte
Neighbors of endometrium cell
Neighbors of microglia
Neighbors of intestine epithelium cell
Neighbors of mononuclear cell
Neighbors of hepatic stellate cell
Neighbors of hepatocyte
Neighbors of kidney mesangial cell
Neighbors of endothelial cell
Neighbors of dendritic cell
Neighbors of Kuppfer cell
Neighbors of inflammatory cell
Neighbors of bone marrow macrophage
Neighbors of peritoneal macrophage
Neighbors of osteoclast
Neighbors of neutrophil
Neighbors of smooth muscle myocyte
Neighbors of astrocyte
Neighbors of bone marrow derived dendritic cell
Neighbors of lung fibroblast
Neighbors of mesothelial cell
Neighbors of mononuclear phagocyte
Neighbors of capillary endothelial cell
Neighbors of immunocompetent cell
Neighbors of granulocyte
Neighbors of cardiac myocyte
Neighbors of cancer-associated fibroblast
Neighbors of myeloid cell
Neighbors of mesenchymal stroma cell
Neighbors of corneal epithelial cell
Neighbors of stem cell
Neighbors of tumor infiltrating macrophage
Neighbors of sinusoidal cell
Neighbors of B-cell
Neighbors of leukocyte
Neighbors of chondrocyte
Neighbors of T-cell
Neighbors of M1 macrophage
Neighbors of mast cell
Neighbors of bone marrow stromal cell
Neighbors of spleen cell
Neighbors of neuroglia
Neighbors of thyroid epithelial cell
Neighbors of hematopoietic cell
Neighbors of podocyte
Neighbors of mammary epithelial cell
Neighbors of conventional dendritic cell
Neighbors of pericyte
Neighbors of antigen-presenting cell
Neighbors of epidermis cell
Neighbors of phagocyte
Neighbors of syncytiotrophoblast
Neighbors of lymphocyte
Neighbors of Langerhans cell
Neighbors of thymic epithelial cell
Neighbors of M2 macrophage
Neighbors of peritoneum cell
Neighbors of skin cell
Neighbors of peripheral lymphocyte
Neighbors of lung
Neighbors of liver
Neighbors of skin
Neighbors of intestine
Neighbors of colon
Neighbors of airway
Neighbors of blood vessel
Neighbors of microvessel
Neighbors of bone
Neighbors of placenta
Neighbors of synovial membrane
Neighbors of uterus
Neighbors of periodontium
Neighbors of brain
Neighbors of breast
Neighbors of islets of Langerhans
Neighbors of joint
Neighbors of kidney glomerulus
Neighbors of immune system
Neighbors of spleen
Neighbors of peritoneum
Neighbors of allantois
Neighbors of alveolus
Neighbors of uterine cervix
Neighbors of arteriole
Neighbors of villus
Neighbors of nose
Neighbors of eye
Neighbors of cornea
Neighbors of hippocampus
Neighbors of vagina
Neighbors of thymus gland
Neighbors of cerebral cortex
Neighbors of trachea
Neighbors of NF-kB family
Neighbors of oxidized LDL
Neighbors of JNK
Neighbors of IL1 family
Neighbors of PPAR
Neighbors of Jun/Fos
Neighbors of PKC
Neighbors of PI3K
Neighbors of STAT family
Neighbors of mitogen-activated protein kinase
Neighbors of IFNAR ligand
Neighbors of transforming growth factor
Neighbors of TLR
Neighbors of cytokine
Neighbors of interferon
Neighbors of JAK
Neighbors of MEK1/2
Neighbors of Ras GTPase
Neighbors of PKA
Neighbors of ovalbumin
Neighbors of LDL
Neighbors of IKBK
Neighbors of protein tyrosine kinase
Neighbors of IgG
Neighbors of AMPK
Neighbors of LXR
Neighbors of T-cell receptor
Neighbors of histone deacetylase
Neighbors of GPCR
Neighbors of lectin
Neighbors of fibrinogen
Neighbors of aldehyde reductase
Neighbors of TSH
Neighbors of NOS
Neighbors of proteasome endopeptidase complex
Neighbors of class nuclear receptor with C4 zinc fingers
Neighbors of PP2B
Neighbors of AHR subfamily
Neighbors of ITG
Neighbors of endostatins
Neighbors of TORC1
Neighbors of histone
Neighbors of neuropeptides
Neighbors of caspase
comon ps_pos, pprarg_neg targets
Model of PPARG signaling in psoriasis
PPARG negative regulators and targets
Model of PPARG related pathways in psoriasis (short version)
sars-cov no binding
dsRNA induces innate immunity and INFs in alveolar cells
Dendritic Cell Activation in COVID19
1_Insufficient activation of immune response in the middle ear epithelium cells in otitis media
3_Role of alveolar macrophages in pulmonary tissue destruction in COPD
4_1_Polymorphisms associated with inflammatory bowel diseases
5_Human papilloma virus E6 and E7 proteins promote epithelial cell proliferation
1_Microangiopathy in diabetic neuropathy
drug-target pairs direct regulation
drug-target moltransport

Group Genes with Mutations Associated with Systemic Scleroderma
Genes with Polymorphisms Associated with Migraine
Genes with Mutations Associated with Endometriosis
other partners for SARS

Source curated
ResNet
GO component

MedScan ID 3552

LocusLink ID 3552
16175
24493
281250

Alias interleukin-1A
RP23-160G19.8
Interleukin-1 large subunit
preinterleukin 1 alpha
IL1alpha
preinterleukin 1
hemopoietin 1
interleukin IL1A
IL1F I
interleukin 1 alpha
IL1A
interleukin IL1alpha
interleukin 1A
OTTHUMP00000203692
interleukin IL1F1
interleukin IL1F I
Hematopoietin I
Hematopoietin-1
preinterleukin I
OTTMUSP00000016430
pro-interleukin-1-alpha
IL1F1
Interleukin-1 alpha subunit
IL1
IL-1A
IL1-ALPHA
IL-1 alpha
interleukin-1 alpha
IL-1F1
interleukin 1, alpha
IL1A (IL1F1)
IL1 alpha

GO ID 0005507
0005125
0005149
0006915
0034605
0002248
0019221
0035234
0097192
0001660
0006955
0070498
0008285
2001240
0045766
0051781
0050715
0010628
0045086
0045840
0050714
0045944
0010575
0046688
0005829
0005576
0005615
0006954
0031424
1904445
0070374
0043123
0046330
0032755
0071639
2000391
1902624
0032308
0010893
0032874
0032956
0051930
0009986
0005737
0005886
0002526
0007507
0010469
0033591
0010332
0009408
0001666
0032496
0014070
0010033
0010243
0010193
0007283
0042060
0006916
0002437
0043066
0005515
0005150
0008283
0008083
0004871
0007267
0006935
0000074

KEGG ID hsa:3552
mmu:16175
rno:24493

MedLine Reference 10432220
12193539
12270120
12438087
12479028
12534936
12785009
12878449
14643175
15025948
15032628
15063785
15154090
15467353
15671867
15990800
16083355
16616101
16825798
16905534
17117141
2471704
10226804
10349636
10452974
10622417
10651053
10744718
10830786
11042159
11076861
11217851
11342576
11518254
11536012
11698278
11717188
11754748
11773602
11809690
11840457
11871152
11883745
11899425
11959104
11988319
11991723
12010793
12012430
12070778
12102659
12112371
12151598
12193704
12270723
12466851
12477932
12598651
12663678
12799211
1284644
12975454
1349539
1353383
1362103
1371115
1421760
14612453
14662844
14744933
14966082
15232066
15271886
1531270
15314695
15331419
1533388
15381720
1552283
1552482
15549727
15591249
15613243
15684062
1572101
1577194
15922486
16026578
16046471
1611993
16137777
16141072
16141073
16256210
16415102
1649220
16517748
16565512
16567518
16569679
1672162
16825293
1685143
1686838
16936270
1828262
1828896
1970329
1970330
2166945
2267629
2419912
2466396
2613234
2759422
2889668
3022289
3149717
6209582
7476020
7539003
7579389
7752808
7819439
7826951
7848516
7873879
7902327
7958862
7959775
8001745
8012118
8027056
8031998
8138038
8177505
8207122
8207237
8224251
8231109
8260598
8268655
8288218
8288233
8306498
8327661
8352883
8432536
8449520
8462855
8464030
8482578
8524866
8543912
8578682
8630372
8699818
8751373
8770556
8798439
8816919
8818542
8833235
8838580
8854867
8881659
8920166
8932996
8953518
9344502
9565638
9809553
9854157
9886396
10441334
10512743
10625660
10748004
10860666
10861041
10953177
10998424
11093146
11145836
11278614
11448121
11466363
11554782
11574262
11774556
11774564
11940570
11991668
11991722
12037600
12047332
12051868
12101079
12115182
12149413
12209090
12220547
12242547
12362317
12370389
12445604
12453471
12519748
12528118
12528119
12530978
12613995
12631337
12651617
12667716
12673844
12710950
12714264
12742380
12746488
12913118
12928381
12930304
12931024
12946945
13679381
14633625
14674121
14688369
14705223
14983027
15007345
15009111
15036245
15039285
15082121
15117956
15130917
15381245
15468358
15489227
15514971
15563458
15587751
15638425
15679580
15732864
15737206
15745939
1584804
15951664
15954918
15974847
15986200
16101131
16246569
16291395
16318580
16378839
16410064
16410066
16428739
16433908
16478776
16504015
16564702
16564703
16619041
16684536
1675504
16788102
16879223
16888077
16945028
16971486
16978691
17012236
1924307
2635664
2783369
2989698
2994016
3485152
3486405
3493774
7494249
7499244
7526541
7566121
7695626
7818827
7857652
7878046
8188271
8370968
8436814
8621446
9169134
9820540
15253926
17174540
3261832
3262865
15489334
16636934
16965825
17197697
17205326
17244613
17290104
17293495
17309781
17335371
17335373
17360358
17371964
17378887
17440718
17449468
17460270
17473736
17541168
17621543
2346741
3281727
8346241
11418636
11466424
12878687
14634130
17277081
17283139
17307724
17609389
3126184
17610660
17548042

Organism Homo sapiens {Organism urn:agi-taxid:9606}
Mus musculus {Organism urn:agi-taxid:10090}
Rattus norvegicus {Organism urn:agi-taxid:10116}
Homo sapiens
Mus musculus
Rattus norvegicus
Bos taurus

Mouse chromosome position 2 62.9 cM
2 73.0 cM

OMIM ID 147760

Rat chromosome position 3q36

Hugo ID 5991
HGNC:5991

Human chromosome position 2q14.1
2q14

Swiss-Prot Accession P01583
P01583.1
P01582
Q3U0Y6
P01582.1
P16598
P16598.1
Q53QF9
Q7RU02
Q546R9
Q62161
Q71VD0
Q9ESW2
IL1A_HUMAN
IL1A_MOUSE
IL1A_RAT
Q53QF9_HUMAN
Q3U0Y6_MOUSE

PIR ID A23385
A01846
JX0064

GenBank ID NC_000002
NM_000575
NP_000566
NG_008850
AC079753
AC112235
AAX93054
AF536338
AAM96189
BN000002
CAD29871
CH471217
EAW73604
X03833
CAA27448
AA856674
AK314850
BAG37367
BC013142
AAH13142
BC035169
BT007014
AAP35660
CA307202
CR457414
CAG33695
M15329
AAA59133
X02531
CAA26371
X02851
CAA26604
X56086
CAA39566
P01583
NC_000068
XM_006498793
XP_006498856
NM_010554
NP_034684
XM_006498794
XP_006498857
AF010237
AAC28999
AL772347
AY902318
AAX90603
CH466519
EDL28236
EDL28237
AK156449
BAE33715
BC003727
AAH03727
M14639
AAA40058
X01450
CAA25682
P01582
NC_005102
NM_017019
NP_058715
AC_000071
AABR07053712
AABR07053713
AABR07072926
AAHX01025007
AAHX01025008
AF016188
AAD01583
CH473949
EDL80161
EDL80162
AJ245642
CAC03995
AJ245643
CAC03996
D00403
BAA00306
KF027366
AHW98144
P16598
ABM84782
AAHY01020659
ABM81601
DQ893856
AMYH02004593
AC_000024
AABR06026122
AABR06026123
XP_006498855
AC_000134
NC_018913
DQ890675
ABBA01074249
CAM15804
XM_006498792
NT_022135
NW_001838841
NW_921474
AC_000045
Q53QF9
NT_039207
NW_001030694
Q3U0Y6
Q62161
NW_047658
NW_001084813
Q71VD0
Q9ESW2
Q546R9
NW_000178
124301
220783
4102785
81870927
81872523
81887923
9844629
9844631
123796899
124298
13277632
200757
3282326
52669
62635466
74224223
81863067
119594010
123994361
124297
15341913
186278
22385324
28317371
30582867
33786
33795
35661
48146945
62702127
74740635
755744
NT_086624
124296
163199
163227
445
AAA30583
AAA30590
CAA31017
M36182
M37210
NC_007309
NM_174092
NP_776517
NW_001492942
P08831
X12497
123979544
123857683
148696289
148696290
149023267
149023268

Swiss-Prot ID IL1A_HUMAN
IL1A_MOUSE
IL1A_RAT
Q3U0Y6_MOUSE
Q53QF9_HUMAN

Cell Localization Secreted
Extracellular

Ensembl ID ENSG00000115008
ENSP00000263339.3
ENST00000263339.3
ENSMUSG00000027399
ENSMUSP00000028882.1
ENSMUST00000028882.1
ENSRNOG00000004575
ENSRNOP00000071252.1
ENSRNOT00000080818.1
ENSP00000263339
ENST00000263339
ENSMUST00000028882
ENSRNOT00000080818
ENSRNOP00000071252
ENSMUSP00000028882

MGI ID MGI:96542
96542

RGD ID 2890

TCDB ID 1.A.109.1.1

Unigene ID Hs.1722
Rn.12300
Mm.15534
Bt.191

Homologene ID 480

Shape Rhomb

IPI ID IPI00136895
IPI00213945
IPI00003096
IPI00192438
IPI00781873

Microarray ID 94755_at

Homo sapiens Chromosome position 2q14

Ensembl Transcript ID ENST00000263339
ENST00000409071

FunctionalClass interleukin-1, Type I receptor binding
signal transducer
cytokine
growth factor
interleukin-1 receptor binding
protein binding

Bos taurus Chromosome position 11

Mus musculus Chromosome position 2 73.0 cM

KEGG pathway Hematopoietic cell lineage
Type I diabetes mellitus
Apoptosis
Cytokine-cytokine receptor interaction
MAPK signaling pathway

Rattus norvegicus Chromosome position 3q36

Ensembl Gene ID ENSG00000115008

LocatorString digtext:C:\Documents and Settings\yuryev\My Documents\Customers\Kristina Hettne\CPRS input entities.txt
pmquery:invasive+breast+cancer