Pathway
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Alzheimer's Disease
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Skin Aging
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Apoptosis of Cochlear Hair Cells (Noise-Induced, Mouse Model)
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Oncogene Induced Cellular Senescence
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Melatonin Effects on Circadian Cycle
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SIRT6 Signaling in Aging
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SIRT1 Signaling in Aging
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Fatty Acids Cause Oxidative Stress and Mitochondria Decline in Aging
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Protein Oxidation and Aggregation in Aging
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Extracellular Matrix Reformation in Aging
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NOD-like Receptors
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Scavenger Receptors in Platelet Activation
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Toll-like Receptor Independent Sterile Inflammation
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Necrosis
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Lipoxin A4/FPR2-Related Neutrophil Depression
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Eicosanoids in Inflammation
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Neutrophil Activation via LTB4/Polyisoprenyl Phosphate Signaling
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Eosinophil Activation
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Macrophage M1 Lineage
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CD16/CD14 Proinflammatory Monocyte Activation
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Neutrophil Activation via FCGR3B
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Neutrophil Degranulation via FPR1 Signaling
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Neutrophil Chemotaxis
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Neutrophil Activation via Adherence on Endothelial Cells
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Melatonin in Cell Survival and Antioxidant Response
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Scavenger Receptor OLR1 in Inflammation Related Endothelial Dysfunction
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RAGE/AGER and S100 Proteins in Cardiovascular Injury
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Dilated Cardiomyopathy
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Endothelial Cell Dysfunction in Pulmonary Hypertension
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Smooth Muscle Cell Dysfunction in Pulmonary Hypertension
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Reperfusion Injury in Myocardial ischemia
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Myocardial Infarction
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Preconditioning Ischemia
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Vascular Reactivity in Raynaud Disease
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Cold Stress and Adrenoceptor alpha 2C Signaling in Raynaud Disease
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NO Synthesis in Early Vasospasm
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Hemoglobin Reduction and Leukocyte Adhesion Initiate Vasospasm
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Sebocyte Proliferation in Acne Vulgaris
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Androgens Synthesis in Sebocytes
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Cell Cycle Dysregulation in Melanoma
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Melanoma
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MITF as a Regulator of Melanoma Cell Development
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Extracellular Matrix Degradation in Skin Aging
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Melanocyte Role in Skin Aging
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Apoptotic Keratinocytes Clearance Recession in Systemic Lupus Erythematosus
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Plasmacytoid Dendritic Cell in Diabetes Mellitus Type 1
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Toll-like Receptors in beta-Cell
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Macrophage Function in Diabetes Mellitus Type 1
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Conventional Dendritic Cell Role in Diabetes Mellitus Type 1
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beta-Cell Death in Diabetes Mellitus Type 2
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Advanced Glycation End Products Pathway in Diabetic Microangiopathy
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Polyol Pathway in Diabetic Microangiopathy
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Peripheral Tissue Microangiopathy
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Tubular Cell Dysfunction in Progressive Diabetic Nephropathy
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Endothelial Cell Dysfunction in Early Diabetic Nephropathy
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Oxidative Stress in Diabetic Neuropathy
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AGE Related Insulin Resistance in Skeletal Muscles
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Lipid Metabolism Impairement in non-Alcoholic Fatty Liver Disease
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beta-Cell Recovery in Diabetes Mellitus
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Hyperglycemia and Hyperlipidemia Trigger beta-Cell Apoptosis
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FOXO1 and SREBP-1C Role in beta-Cell Suppression (Rodent Model)
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Hashimoto's Thyroiditis
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Hashimoto's Thyroiditis Triggers
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Fatty Acids in Hypertension and Atherosclerosis Development
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Macrophage Dysfunction
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Eosinophil Survival in Asthma
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Eosinophil Activation and Degranulation in Asthma
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Airway Smooth Muscle Cell Contraction
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Neutrophil Degranulation via FPR1/IL8
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CFTR Facilitates Oxidative Stress in Airway Epithelium in CF
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Airway Epithelial Cell Dysfunction
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Monocytes Function in Gout
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Dendritic Cell Dysfunction in Psoriatic Arthritis
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Skin Fibrosis
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PAPA Syndrome
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TNF Receptor Associated Periodic Syndrome
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Cryopyrin (NLPR3) Associated Periodic Syndromes
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Familial Cold Autoinflammatory Syndrome 2
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Familial Mediterranean Fever
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Glutamate Toxiicity Effects on Striatum Medium Spiny Neurons in Hantington's Disease
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IL6 Overexpression After Contraction in Skeletal Muscles in Muscular Dystrophies
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Muscular Dystrophies
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Dystrophin Glycoprotein Complex Signaling in Muscular Dystrophies
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Ca2+ Toxicity in Neurons
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Ketogenic Diet Mechanism (Hypothesis)
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PARK7 and LRRK2 in Young Onset Parkinson's Disease
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Neurotoxin Effects in Parkinson's Disease
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SNCA in Young Onset Parkinson's Disease
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Glutamate Mediated Excitotoxicity in Amyotrophic Lateral Sclerosis
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Oxidative Stress, All-Trans-Retinal and Lipofuscin Toxicity in AMD
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Ca2+ Toxicity in Lens Cells
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Diabetes Induced Cataract
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Age-Related Cataract
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Cataract, Congenital
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Aminoglycosides and Cisplatin Induced Ototoxicity (Mouse Model)
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Immune System Role in Otitis Media
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Alveolar Macrophages Dysfunction in COPD
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Neutrophil Associated Lung Damage in Chronic Obstructive Pulmonary Disease
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CAV1 Dependent Senescence of Lung Fibroblasts
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VEGFA High Expression Level in Pulmonary Emphysema
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T-Cell Cytotoxic Activation
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Mucin Hyperproduction in Goblet and Mucous Cells
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Penile Detumescense Augmentation Mechanisms
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Advanced Glycation End Products in Diabetes or Age Related Erectile Dysfunction
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Ammonia Effects on Brain Cells
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CD157/ITGB2 Signaling in Myeloid Cell
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Acetaminophen Induced Hepatotoxicity
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Asbestosis- and Silicosis-Associated Inflammation Provokes Cancer Development
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Oxidized LDL/OLR1 Activates Cell Proliferation in Cancer
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HIF1A as Master Regulator of Angiogenesis in Cancer
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Invadopodia Formation in Cancer Cells
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Respiratory Chain Impairment in Cancer
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Metabolic Effects of Oncogenes and Tumor Suppressor in Cancer Cells
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Glutamine in Cancer Metabolism
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Tumor Infiltrating Macrophages in Cancer Progression and Immune Escape
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Myeloid Derived Suppressor Cells in Cancer Immune Escape
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HIF1 Signaling
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ER Stress (Unfolded Protein Response)
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Oxidative Stress Protection via AHR-NFE2L2-NQO1 Signaling in Keratinocytes
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e
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pathway 4
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sialic
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Model of PPARG signaling in psoriasis
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2_Hyperseborrhea in acne vulgaris
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2_Oxidative stress, all-trans-retinal, and lipofuscin toxicity in agerelated macular degeneration
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2_Diabetes-induced cataract
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3_Congenital cataract
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1_Age-related cataract
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1_Low-density lipoprotein internalization and the accumulation of lipids in atherosclerosis
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3_Arterial wall inflammation and calcification in atherosclerosis
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2_The intense proliferation and contractile activity of smooth muscle cells in pulmonary hypertension
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1_Cigarette smoke causes dysfunction and production of inflammatory mediators in alveolar epithelial cells
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3_Role of alveolar macrophages in pulmonary tissue destruction in COPD
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2_3_Eosinophilia and neutrophilia in asthma: Neutrophil chemotaxis and activation
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4_1_Airway smooth muscle cells contraction
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1_Antigen-presenting cells promote islet dysfunction and immune system activation in T1D
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1_Microangiopathy in diabetic neuropathy
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1_Glutamate and calcium excitotoxicity of motor neurons in ALS
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Figure 4_Diabetes mellitus Type 1: conventional dendritic cell
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