Protein JUN

URN urn:agi-llid:3725
Total Entities 0
Connectivity 7144
Name JUN
Description jun proto-oncogene
Notes This gene is the putative transforming gene of avian sarcoma virus 17. It encodes a protein which is highly similar to the viral protein, and which interacts directly with specific target DNA sequences to regulate gene expression. This gene is intronless and is mapped to 1p32-p31, a chromosomal region involved in both translocations and deletions in human malignancies. [provided by RefSeq, Jul 2008]
Primary Cell Localization Nucleus
Class Transcription factor

Pathway Osteoarthritis
Skin Aging
Oncogene Induced Cellular Senescence
MTHFR Activity Regulation
Melatonin Effects on Circadian Cycle
N-cell: Neurotensin Production
Dopamine Receptors Signaling
Prolactin Production
Thrombopoietin Receptors Signaling in Platelet Maturation
Cortisol in Resolving Inflammation
T-Cell Dependent B-Cell Activation
T-Cell Independent B-Cell Activation
Natural Killer Cell Activation through C-Type Lectin-like Receptors
Natural Killer Cell Activation through ITAM-Containing Receptors
Natural Killer Cell Activation through ITSM-Containing Receptors
Natural Killer Cell Activation
CD8+ T-Cell Activation
Plasmin Effects in Inflammation
Toll-like Receptor Independent Sterile Inflammation
Lipoxin A4/FPR2-Related Neutrophil Depression
Neutrophil Activation via LTB4/Polyisoprenyl Phosphate Signaling
Mast-Cell Activation without Degranulation through CXCR4 Signaling
CD16/CD14 Proinflammatory Monocyte Activation
anti-Inflammatory Function of Macrophage M2 Lineage
AXL Receptor Inhibits Macrophages and Dendritic Cells Function
Neutrophil Recruitment and Priming
Vascular Smooth Muscle Cell/Pericyte Migration and Proliferation
Vascular Endothelial Cell Activation by Blood Coagulation Factors
Adipokines Production by Adipocyte
Nociception Expression Targets Signaling
NTSR1 Expression Targets
ADRA1A -> IL6 Production
CNR1/2 -> IL1B/2/4/6/10 Production
DRD2 Expression Targets
DRD1/5 Expression Targets
CHRM1 -> IL2 Production
PTGER2/3 -> Inflammation-Related Expression Targets
IL1B Expression Targets -> Nociception
Melatonin in Cell Survival and Antioxidant Response
Cell Cycle Overiew
G0/G1 Phase Transition
SCF/FBXW7 Complex
Proteins Involved in Atherosclerosis
Dendritic Cells Function in Atherosclerosis
RAGE/AGER and S100 Proteins in Cardiovascular Injury
Proteins Involved in Hypertrophic Cardiomyopathy
Cardiomyocyte Hypertrophy
Hypertrophic Cardiomyopathy
Endothelin Signaling in Arterial Hypertension
Arterial Hypertension
Endothelial Cell Dysfunction in Arterial Hypertension
Aldosterone Synthesis Chronic Regulation
Smooth Muscle Cell Dysfunction in Arterial Hypertension
TRPM4/6/7/8 Signaling in Arterial Hypertension (Hypothesis)
Myocardial Remodeling
Proteins Involved in Myocardial Ischemia
Sebocyte Proliferation in Acne Vulgaris
Inflammatory Reaction in Acne Vulgaris
Mast-Cells Activation in Atopic Dermatitis
IL17 Signaling in Psoriasis
Proteins Involved in Psoriasis
IL22 Induces Keratinocyte Proliferation in Psoriasis
Proteins Involved in Photoaging
Th0-Cell Aberrant Activation in Systemic Lupus Erythematosus
B-Cell Activation in Systemic Lupus Erythematosus
Acute Cytotoxic CD8+T-Cell Response against Melanocytes
Humoral Immunity in Vitiligo
CD8+ T-Cell Response to Self-Determinants in Diabetes
Natural Killer T-Cell Roles in Diabetes Mellitus Type 1
Natural Killer Cell in Diabetes Mellitus Type 1
Peripheral Tolerance to Autoantigens Recession in Diabetes Mellitus Type 1
Advanced Glycation End Products Pathway in Diabetic Microangiopathy
Protein Kinase C in Diabetic Microangiopathy
Peripheral Tissue Microangiopathy
Tubular Cell Dysfunction in Progressive Diabetic Nephropathy
Endothelial Cell Dysfunction in Progressive Diabetic Nephropathy
Endothelial Cell Dysfunction in Early Diabetic Nephropathy
Mesangial Cell Dysfunction in Diabetic Nephropathy
Microangiopathy in Diabetic Neuropathy
Proliferative Diabetic Retinopathy
Proteins Involved in Insulin Resistance
Adiponectin Synthesis Declines in Insulin Resistance
Hepatic Stellate Cells in non-Alcoholic Fatty Liver Disease
beta-Cell Destruction through Cytokines in Diabetes Mellitus
beta-Cell Mass Regulation
Hypothyrodism Associated Hyperprolactinemia
DRD2 Pharmacological Inhibition in Hyperprolactinemia
Ethanol Induced Efects in Hyperprolactinemia
Thyroid Dysfunction
GNRH Signaling Impairment in Hypogonadotrophic Hypogonadism
Myocyte Dysfunction in Hypoparathyroidism
Adipokines Production by Adipocyte Impaired in Obesity
Prolactinoma Overiew
CD8+ T-Cell Response in Celiac Disease
Proteins Involved in Colorectal Neoplasms
GUCY2C Signaling in Colorectal Cancer
OipA Signaling in Helicobacter Pylori Infection
CagA Phosphorylation Dependent Signaling
Peutz-Jeghers Syndrome
Epithelial Cell in the Innate Immune Response in Ulcerative Colitis
T-Cell Cytotoxic Response in Ulcerative Colitis
Proteins Involved in Acute Myeloid Leukemia
Antiphospholipid Antibodies in Endothelial Cell
Proteins Involved in Antiphospholipid Syndrome
B-Cell Acute Lymphoblastic Leukemia
B-Cell Chronic Lymphocytic Leukemia
Chronic Myeloid Leukemia
Follicular Lymphoma
Osteoclast Activation in Multiple Myeloma
Multiple Myeloma
Antiphospholipid Antibodies and Endothelial Cell Interaction
T-Cell Acute Lymphoblastic Leukemia
Proteins Involved in Hepatocellular Carcinoma
NOTCH Signaling in Hepatocellular Carcinoma
WNT Signaling in Hepatocellular Carcinoma
Hepatocellular Carcinoma
Growth Factor Signaling in Hepatocellular Carcinoma
Pancreatic Ductal Carcinoma
Growth Factor Signaling in Pancreatic Neoplasms
Pancreatic Neuroendocrine Tumors
TRPM7/8 in Pancreatic Adenocarcinoma
TGFBR Signaling in Pancreatic Neoplasms
TSLP Signaling in Bronchial Epithelial Cell in Asthma
Airway Smooth Muscle Cell High Rate Proliferation
Osteoclast Activation in Gout
Monocytes Function in Gout
TNF and IL1B Induce Metalloproteinase Synthesis in Osteoarthritis
Ovulation Block
FSH Action in Polycystic Ovary Syndrome
Synovial Fibroblast Activation in Psoriatic Arthritis
Keratinocyte Activation in Psoriatic Arthritis
Proteins Involved in Psoriatic Arthritis
PTPN22 Role in Rheumatoid Arthritis
Synovial Fibroblast Proliferation in Rheumatoid Arthritis
Osteoclast Activation in Rheumatoid Arthritis
Synovial Fibroblast Activation by Citokines in Rheumatoid Arthritis
TLR2 Induced Synovial Fibroblast Activation in Rheumatoid Arthritis
Autocrine Cytokine/Chemokine Loops in Systemic Scleroderma
B-Cells Function in Systemic Scleroderma
Skin Fibrosis
CCR5 Signaling in Macrophages
CD8+ T-Cell Action Impairment in HIV Type 1 Infection
Diabetes Induced Periodontitis
Estrogen Effects on Pregnancy Gingivitis
Majeed Syndrome
Hereditary Breast and Ovarian Cancer Syndrome
Cowden Syndrome
Proteins Involved in Huntington Disease
Oxytocin Signaling in Brain Nerve Cell (Hypothesis)
IL6 Promotes Inflammation in Muscular Dystrophies
IL6 Overexpression After Contraction in Skeletal Muscles in Muscular Dystrophies
Ca2+ Overload in Muscular Dystrophies
Muscular Dystrophies
Dystrophin Glycoprotein Complex Signaling in Muscular Dystrophies
IGF1 Role in Muscle Hypertrophy
Proteins Involved in Osteopetrosis
Osteoblast Function Decline in Osteoporosis
Osteoclast Activation in Postmenopause
Proteins Involved in Alzheimer's Disease
Metals and Amyloid beta Toxicity in Alzheimer's Disease
Apoptosis and Immediate Early Gene Activation in Epileptiform Disorders
Glioma Invasion Signaling
Proteins Involved in Medulloblastoma
Proteins Involved in Parkinson's Disease
Proteins Involved in Amyotrophic Lateral Sclerosis
Microglia and Motor Neuron Interaction Dysregulation
Proteins Involved in Breast Cancer Related to WNT Signaling Pathway
Proteins Involved in Breast Cancer Related to ESR1 Signaling Pathway
Proteins Involved in Breast Cancer Related to NOTCH Signaling Pathway
WNT Signaling in Breast Cancer
Proteins Involved in Breast Cancer Related to ERBB2/VEGFR/Akt Signaling Pathway
ERBB/VEGFR/Akt Signaling in Breast Cancer
IGF1R/AKT Signaling in Breast Cancer
ESR1/ERBB Positive Luminal Breast Cancer
Proteins Involved in Breast Cancer Related to IGF1R/Akt Signaling Pathway
Breast Cancer
ESR1 Signaling in Breast Cancer
NOTCH1 Signaling in Breast Cancer
Endometrial Cancer
Endometrioid Endometrial Cancer
Clear Cell Endometrial Cancer and Papillary Serous Endometrial Cancer
Angiogenesis in Endometriosis
Coagulation Factors and PAR1/2 Receptors (F2R/F2RL1) in Endometriosis
Leptin Role in Endometriosis
Proteins Involved in High-Grade Serous Ovarian Carcinoma
Endometrioid Ovarian Carcinoma
Proteins Involved in Endometrioid Ovarian Carcinoma
Clear Cell Ovarian Carcinoma
Proteins Involved in Mucinous Ovarian Carcinoma
High-Grade Serous Ovarian Carcinoma
Low-Grade Serous Ovarian Carcinoma
Proteins Involved in Low-Grade Serous Ovarian Carcinoma
Ovarian Cancer
Proteins Involved in Clear Cell Ovarian Carcinoma
Mucinous Ovarian Carcinoma
MIF Role in Cholesteatoma
HMGB1/RAGE Signaling in Middle Ear Cholesteatoma
Subepithelial Fibroblasts in Middle Ear Cholesteatoma
Cholesteatoma
HPV Infection and Cancer
HPV E5 Regulates EDNRA and EGFR Signaling Pathway in Keratinocytes
Kruppel-like Factor 6 Signaling in Prostate Cancer
TRPM8 Effects in Prostate Cancer (Hypothesis)
ER Stress in Macular Degeneration
Steroids Induced Cataract
VEGFA in Neovascular Glaucoma
PGF2-alpha Effect on Treatment
MUC5AC Expression by NTHi and S. Pneumoniae
Alveolar Macrophage Negative Regulation Declined in COPD
Alveolar Macrophages Dysfunction in COPD
VEGFA Low Expression Level in Chronic Bronchitis
T-Cell Cytotoxic Activation
Alveolar Epithelial Cell Dysfunction in COPD
WNT Signaling in Cystic Kidney Disease
Polycystins Mutation Effects in Cystic Kidney Disease
Plasmin Role in Glomerulonephritis
Endothelial Cell Dysfunction in Glomerulonephritis
Mesangial Cell Dysfunction in Glomerulonephritis
Interstitial Fibroblasts in Pyelonephritis
CD38/CD3 -> JUN/FOS/NF-kB Signaling in T-cell Proliferation
CD38/CD19 -> JUN/FOS/NF-kB Signaling in B-cell Proliferation
CD38 -> cADPR/Calcium Signaling
S100B Expression Targets
ANGPT2 -> STAT Expression Targets
ANGPT2 -> AP-1/CREBBP/MYC Expression Targets
AREG -> AP-1 Expression Targets
Noradrenaline/Gs Expression Targets
Dopamine/Gs Expression Targets
Noreadrenaline/Gq Expression Targets
Epinephrine/Gs Expression Targets
Acetylcholine Expression Targets
Serotonin/Gq Expression Targets
Epinephrine/Gq Expression Targets
Dopamine/Gi Expression Targets
B-Cell Receptor -> AP-1 Signaling
BMP2/BMPR2 Expression Targets
BMP4/BMPR2 Expression Targets
BMP7/BMPR2/ACVR2 Expression Targets
BTC -> AP-1/ATF/CREB Expression Targets
Elevated Receptors -> Expression Targets in Bone and Joint
AGTR1 -> ARRB1/ARRB2 Signaling
CD19 Expression Targets
CD81 -> AP-1 Expression Targets
CD247 Expression Targets
gamma Globulins Expression Targets
CD19/CR2 Expression Targets
CD72 -> CREB/CREBBP Expression Targets
CD8 -> ATF/CREB/CREBBP Expression Targets
CD80 -> NF-kB Expression Targets
CD86 -> NF-kB Expression Targets
Elevated Receptors -> Expression Targets in Myocardium
CXCL12 Expression Targets
CSF2 -> STAT Expression Targets
LIF Expression Targets
Clozapine Induced Granulocytopenia
EGF -> CTNN Expression Targets
EGF -> AP-1/ATF Expression Targets
EGF -> CREB/CREBBP/ELK/SRF/MYC Expression Targets
EGF -> MEF/MYOD/NFATC Expression Targets
EGF -> STAT Expression Targets
EGFR -> AP-1/ATF2 Signaling
EGFR -> AP-1/CREB/ELK/SRF/MYC Signaling
EREG -> AP-1/ATF Expression Targets
Erythropoietin -> NF-kB Expression Targets
Erythropoietin -> AP-1/MYC/CREB Expression Targets
Erythropoietin -> ELK/SRF Expression Targets
F2 -> AP-1/CREB/ELK/SRF/SP1 Expression Targets
F2 -> STAT1/NF-kB Expression Targets
PLG -> AP-1/CREB/ELK/SRF/SP1 Expression Targets
PLG -> STAT1/NF-kB Expression Targets
FGF9 -> AP-1/CREB/MYC Expression Targets
FGF10 -> AP-1/CREB/CREBBP/MYC Expression Targets
FGF2 -> STAT Expression Targets
FGF1 -> AP-1/CREB/ELK/SRF/MYC Expression Targets
FGF18 -> STAT Expression Targets
FGF18 -> AP-1/CREB Expression Targets
FGF1 -> STAT Expression Targets
FGF4 -> AP-1/MYC Expression Targets
FGF7 -> AP-1/CREB/CREBBP/MYC Expression Targets
FGF2 -> AP-1/CREB/CREBBP/ELK/SRF/MYC Expression Targets
FGFR -> AP-1/CREB/CREBBP/ELK/SRF/MYC Signaling
FrizzledR -> JUN/PAX2 Signaling
GCG Expression Targets
FSHR Expression Targets
VIP Expression Targets
GH1/GHR -> NF-kB/ELK/SRF/MYC Expression Targets
GH1/GHR -> STAT Expression Targets
GH1/PRLR Expression Targets
HBEGF -> AP-1/ATF Expression Targets
HGF -> STAT Expression Targets
HGF -> AP-1/CREB/ELK/SRF/MYC Expression Targets
HGFR -> AP-1/CREB/MYC Signaling
TAM Receptor Signaling Activation in Cancer
G0/G1 Cell Cycle Phase Transition Activation in Cancer
RAS/RAF/MAPK Signaling Activation in Cancer
WNT Canonical Signaling Activation in Cancer
Asbestosis- and Silicosis-Associated Inflammation Provokes Cancer Development
RAS/RAF/MAPK Signaling Activation by Blocking of Tumor Suppressors
WNT Signaling Activation by Blocking of Tumor Suppressors
TGFB Signaling activation by Blocking of Tumor Suppressors
VEGFA Dependent Angiogenesis in Cancer
ANGPT/TEK Stimulates Endothelial Cell Migration in Cancer
VEGF Independent Angiogenesis in Cancer
Integrins in Cancer Cell Motility, Invasion and Survival
MTOR/TORC in Cancer Cell Motility and Invasion
Hyaluronic Acid, CD44 and HMMR in Cancer Cell Invasion and Survival
Treg Cells Promote Immunosuppression in Cancer Immune Escape
IGF1 -> MEF/MYOD/MYOG Expression Targets
IGF1 -> STAT Expression Targets
IGF1 -> ELK/SRF/HIF1A/MYC/SREBF Expression Targets
INHBA/ACVR2/BMPR Expression Targets
Insulin -> STAT Expression Targets
Insulin -> CEBPA/CTNNB/FOXA/FOXO Expression Targets
Insulin -> MEF/MYOD Expression Targets
Insulin -> ELK/SRF/HIF1A/MYC/SREBF Expression Targets
CD19 -> JUN/ELK Signaling
ICAM1 -> AP-1/CREB/ELK/SRF Signaling
FibronectinR -> AP-1/ELK/SRF/SREBF Signaling
CTGF -> AP-1/CREB/MYC Expression Targets
ICAM1 Expression Targets
EGFR -> Expression Targets in Skin
IFNG/IFNR Expression Targets
IL7 Expression Targets
IL16 -> AP-1 Expression Targets
IL3 Expression Targets
IL6 Expression Targets
IL2 Expression Targets
PTPRJ Expression Targets
Leptin -> STAT Expression Targets
Leptin -> ELK/SRF Expression Targets
Prostaglandin F Expression Targets
Thromboxane A2 Expression Targets
LPA Expression Targets
PAF/Gq -> AP-1/ATF1/CREB/ERK/SRF Expression Targets
Dronabinol/Anandamide Expression Targets
Morphine Expression Targets
S1P Expression Targets
PGE1 Expression Targets
MTNR1 Signaling
NRG1 -> EP300/ETS/ETV/SP1 Expression Targets
NRG1 -> CREB/CREBBP/ELK/SRF/MYC Expression Targets
NRG1/Catenin Expression Targets
NRG1 -> STAT Expression Targets
NRG1 -> AP-1/ATF Expression Targets
Elevated Receptors -> Expression Targets in Nerve Tissue
NGF -> SMAD3/NF-kB Expression Targets
NGF -> AP-1/TP53/MYC Expression Targets
BDNF Expression Targets
NTF3 Expression Targets
NTF4 Expression Targets
Adenosine Expression Targets
PDGFB -> AP-1/CREB/MYC Expression Target
PDGFD -> AP-1 Expression Targets
PDGF -> AP-1/CREB/CREBBP/MYC Expression Targets
PDGF -> STAT Expression Targets
PDGFR -> AP-1/MYC Signaling
AVP/Gs -> CREB/ELK/SRF/AP-1/EGR Expression Targets
GNRH1 Expression Targets
NTS Expression Targets
GAST Expression Targets in GAST Expression Targets
GNRH2 Expression Targets
POMC Expression Targets
CCL11 Expression Targets
EDN1 Expression Targets
AGT -> CREB Expression Targets
NPY Expression Targets
AVP/Gq -> STAT Expression Targets
TAC1 Expression Targets
AVP/Gs -> STAT Expression Targets
EDN3 Expression Targets
AGT -> STAT Expression Targets
AVP/Gq -> CREB/ELK/SRF/AP-1/EGR Expression Targets
PRL/PRLR Expression Targets
PRL/GHR -> STAT Expression Targets
PRL/GHR -> NF/kB/ELK/SRF/MYC Expression Targets
PDCD1 -> AP-1 Expression Targets
AngiopoietinR -> AP-1 Signaling
EphrinB -> MAPK/JUN/FOS Signaling
NTRK -> AP-1/CREB/ELK/SRF/MYC/SMAD3/TP53 Signaling
CSF1 -> STAT Expression Targets
GAS6 -> AP-1/CREB Expression Targets
FIGF -> AP-1 Expression Target
KITLG -> STAT Expression Targets
KITLG -> AP-1/CREB/CREBBP/MYC Expression Targets
GDNF -> HSF1 Expression Targets
PAF Expression Targets
CSF1 -> AP-1/CREB/CREBBP/MYC Expression Targets
PGF -> AP-1/CREB/CREBBP/MYC Expression Targets
FLT3LG -> AP-1/CREB/CREBBP Expression Targets
TGFBR -> AP-1 Signaling
TGFBR1/AP-1 Signaling
MSTN/ACVR2/BMPR Expression Targets
TNF-alpha/TNFRSF1A Signaling
Lysophosphatidic Acid/LPARs Signaling
JNK/MAPK Signaling
Estrogens/ESR1 Genomic Canonical Signaling
MERTK Signaling
TGF-beta Signaling
BMPR2 Signaling
AXL Receptor Tyrosine Kinase Signaling
TNF-alpha/TNFRSF1B Signaling
VEGF Signaling
Estrogens/ESR1 non-Genomic Signaling
EGFR Signaling
WNT Planar Cell Polarity (PCP) non-Canonical Signaling
HRAS Signaling
ERK/MAPK Canonical Signaling
TCR -> AP-1 Expression Targets
TGFA -> STAT Expression Targets
TGFA -> CTNNB/CTNND Expression Targets
TGFA/AP-1/ATF Expression Targets
TGFA -> CREB/CREBBP/ELK-SRF/MYC Expression Targets
TGFB3-TGFBR2 Expression Targets
TGFB2-TGFBR2 Expression Targets
TGFB1-TGFBR2 Expression Targets
TGFB1-TGFBR1/AP-1 Expression Targets
TGFB1-ACVRL1 Expression Targets
FASLG Expression Targets
TNFSF10 Expression Targets
LTA Expression Targets
TNFSF14 Expression Targets
TNF -> AP-1 Expression Targets
CD72 -> AP-1 Expression Targets
TNFSF13 Expression Targets
TNFSF13B Expression Targets
EDA Expression Targets
EctodysplasinR -> AP-1 Signaling
TNFR -> AP-1/ATF/TP53 Signaling
NGFR -> AP-1/CEBPB/CREB/ELK/SRF/TP53 Signaling
TNFRSF1A -> AP-1/ATF/TP53 Signaling
Thrombopoietin -> AP-1/CREB/CREBBP/MYC Expression Targets
TLR4 -> AP-1 Expression Targets
TLR5 Expression Targets
TLR7 Expression Targets
IL1B -> NO Expression Targets
TLR4 -> AP-1/EGR1/HIF1A Expression Targets
IL1B -> PGE2 Expression Targets
TLR1 -> 2/6 Expression Targets
IL1B Expression Targets
IL1A Expression Targets
TLR9 Expression Targets
TLR -> AP-1 Signaling
VEGFA -> ATF/CREB/ELK-SRF Expression Targets
VEGFA -> STAT Expression Targets
VEGFA -> AP-1/CREBBP/MYC Expression Targets
VEGFA -> CTNNB/CTNND Expression Targets
VEGFR -> AP-1/CREB/MYC Signaling
WNT1 Expression Targets
WNT3A Expression Targets
WNT4 Expression Targets
WNT5A Expression Targets
WNT7A Expression Targets
pathway 3
n
ace2
prarg negative regulators, ps-positive
PPARG negative regulators
pparg expr target_regulators
Neighbors of disease exacerbation
Neighbors of tumor progression
Neighbors of cancer progression
Neighbors of inflammatory status
Neighbors of overall survival
Neighbors of tumor size
Neighbors of mortality
Neighbors of survival rate
Neighbors of infarct size
Neighbors of survival time
Neighbors of functional recovery
Neighbors of insulin sensitivity
Neighbors of bacterial load
Neighbors of cancer survival
Neighbors of lethality
Neighbors of recurrence-free survival
Neighbors of macrophage count
Neighbors of long-term survival
Neighbors of treatment outcome
Neighbors of body weight
Neighbors of tumor promotion
Neighbors of morbidity
Neighbors of mortality rate
Neighbors of exhaustion
Neighbors of radioresistance
Neighbors of cell density
Neighbors of apoptosis rate
Neighbors of viral load
Neighbors of tumor grade
Neighbors of tumor resistance
Neighbors of renal hypertrophy
Neighbors of radiosensitivity
Neighbors of pregnancy outcome
Neighbors of metabolic response
Neighbors of disease exacerbation
Neighbors of tumor progression
Neighbors of cancer progression
Neighbors of inflammatory status
Neighbors of overall survival
Neighbors of tumor size
Neighbors of mortality
Neighbors of survival rate
Neighbors of infarct size
Neighbors of survival time
Neighbors of functional recovery
Neighbors of insulin sensitivity
Neighbors of bacterial load
Neighbors of cancer survival
Neighbors of lethality
Neighbors of recurrence-free survival
Neighbors of macrophage count
Neighbors of long-term survival
Neighbors of treatment outcome
Neighbors of body weight
Neighbors of tumor promotion
Neighbors of morbidity
Neighbors of mortality rate
Neighbors of exhaustion
Neighbors of radioresistance
Neighbors of cell density
Neighbors of apoptosis rate
Neighbors of viral load
Neighbors of tumor grade
Neighbors of tumor resistance
Neighbors of renal hypertrophy
Neighbors of radiosensitivity
Neighbors of pregnancy outcome
Neighbors of metabolic response
Neighbors of cell development
Neighbors of immune response
Neighbors of cell population
Neighbors of T-cell development
Neighbors of inflammatory response
Neighbors of wound healing
Neighbors of angiogenesis
Neighbors of innate immune response
Neighbors of cell function
Neighbors of macrophage activation
Neighbors of cell formation
Neighbors of osteoclast development
Neighbors of epithelial to mesenchymal transition
Neighbors of immunity
Neighbors of cell proliferative response
Neighbors of dendritic cell differentiation
Neighbors of cell survival
Neighbors of osteoclast differentiation
Neighbors of cell phenotype
Neighbors of T-cell proliferation
Neighbors of tissue remodeling
Neighbors of cell adhesion
Neighbors of T-cell activation
Neighbors of endothelial cell proliferation
Neighbors of fibrogenesis
Neighbors of tumor growth
Neighbors of dendritic cell development
Neighbors of tissue repair
Neighbors of cell count
Neighbors of cell infiltration
Neighbors of cell interaction
Neighbors of SMC proliferation
Neighbors of lumen formation
Neighbors of endothelial cell migration
Neighbors of adipogenesis
Neighbors of lipid storage
Neighbors of cell damage
Neighbors of pregnancy
Neighbors of monocyte differentiation
Neighbors of aging
Neighbors of cell motility
Neighbors of bone resorption
Neighbors of fibroblast proliferation
Neighbors of adipocyte differentiation
Neighbors of microglial activation
Neighbors of regeneration
Neighbors of cell migration
Neighbors of cancer growth
Neighbors of stem cell proliferation
Neighbors of smooth muscle cell migration
Neighbors of hepatic regeneration
Neighbors of transendothelial migration
Neighbors of osteoclast formation
Neighbors of cell invasion
Neighbors of heart function
Neighbors of hemopoiesis
Neighbors of bone remodeling
Neighbors of ossification
Neighbors of T-cell function
Neighbors of immune system function
Neighbors of lung development
Neighbors of autophagy
Neighbors of monocyte adhesion
Neighbors of transcription activation
Neighbors of senescence
Neighbors of hepatocyte proliferation
Neighbors of cell transdifferentiation
Neighbors of neuroprotection
Neighbors of stem cell differentiation
Neighbors of endothelial cell function
Neighbors of neuronal death
Neighbors of cell growth
Neighbors of ROS generation
Neighbors of epithelial cell proliferation
Neighbors of cancer cell growth
Neighbors of sensitization
Neighbors of macrophage function
Neighbors of cellular immune response
Neighbors of cellular senescence
Neighbors of colony formation
Neighbors of macrophage differentiation
Neighbors of cell differentiation
Neighbors of keratinocyte proliferation
Neighbors of stem cell migration
Neighbors of life span
Neighbors of psoriasis
Neighbors of inflammatory disease
Neighbors of rheumatoid arthritis
Neighbors of atherosclerosis
Neighbors of fibrosis
Neighbors of arthritis
Neighbors of injury
Neighbors of atherogenesis
Neighbors of vascular remodeling
Neighbors of metastasis
Neighbors of carcinogenesis
Neighbors of inflammation
Neighbors of tumor microenvironment
Neighbors of pathological angiogenesis
Neighbors of obesity
Neighbors of vascular disease
Neighbors of diabetes mellitus
Neighbors of asthma
Neighbors of pneumonia
Neighbors of hyperplasia
Neighbors of osteoarthritis
Neighbors of chronic obstructive pulmonary disease
Neighbors of reperfusion injury
Neighbors of airway inflammation
Neighbors of hepatitis
Neighbors of insulin resistance
Neighbors of infection
Neighbors of vascular injury
Neighbors of liver injury
Neighbors of neuroinflammation
Neighbors of sepsis
Neighbors of death
Neighbors of type 1 diabetes
Neighbors of autoimmune disease
Neighbors of ischemic stroke
Neighbors of dermatitis
Neighbors of neutrophil infiltration
Neighbors of heart disease
Neighbors of diabetic nephropathy
Neighbors of hepatocellular carcinoma
Neighbors of gastric cancer
Neighbors of colorectal cancer
Neighbors of cardiac remodeling
Neighbors of breast cancer
Neighbors of ischemia
Neighbors of systemic lupus erythematosus
Neighbors of melanoma
Neighbors of cartilage degeneration
Neighbors of interstitial fibrosis
Neighbors of neoplasm invasion
Neighbors of heart failure
Neighbors of lung disease
Neighbors of pulmonary fibrosis
Neighbors of cardiovascular disease
Neighbors of cancer
Neighbors of cerebral ischemia
Neighbors of neoplasm
Neighbors of neointima
Neighbors of atrophy
Neighbors of respiratory hypersensitivity
Neighbors of myocardial fibrosis
Neighbors of liver disease
Neighbors of prostate cancer
Neighbors of hypertrophy
Neighbors of ovarian cancer
Neighbors of pancreatic cancer
Neighbors of hypertension
Neighbors of intimal hyperplasia
Neighbors of kidney mesangial cell
Neighbors of osteoclast
Neighbors of T-cell
Neighbors of lung
Neighbors of liver
Neighbors of skin
Neighbors of brain
Neighbors of nerve
Neighbors of NF-kB family
Neighbors of JNK
Neighbors of IL1 family
Neighbors of PPAR
Neighbors of Jun/Fos
Neighbors of NFKBI
Neighbors of PKC
Neighbors of PI3K
Neighbors of STAT family
Neighbors of mitogen-activated protein kinase
Neighbors of cytokine
Neighbors of interleukin
Neighbors of JAK
Neighbors of PDGF
Neighbors of Ras GTPase
Neighbors of ERK1/2
Neighbors of growth factor
Neighbors of PKA
Neighbors of LDL
Neighbors of NF-AT family
Neighbors of beta adrenoceptor
Neighbors of chorionic gonadotropin
Neighbors of IKBK
Neighbors of protein tyrosine kinase
Neighbors of NAD(P)H oxidase
Neighbors of SMAD subfamily
Neighbors of LXR
Neighbors of p38
Neighbors of estrogen receptor
Neighbors of T-cell receptor
Neighbors of histone deacetylase
Neighbors of PDGF-BB
Neighbors of HIF-1
Neighbors of GPCR
Neighbors of prostaglandin-endoperoxide synthase
Neighbors of aldehyde reductase
Neighbors of mitogen-activated protein kinase kinase
Neighbors of TSH
Neighbors of endothelin
Neighbors of proteasome endopeptidase complex
Neighbors of histone H3
Neighbors of alpha2 adrenoceptor
Neighbors of vitronectin receptor (integrin)
Neighbors of PP2A
Neighbors of SAPK
Neighbors of WNT
Neighbors of gonadotropins
Neighbors of immunoglobulin
Neighbors of PP2B
Neighbors of phospholipase
Neighbors of endostatins
Neighbors of FSH
Neighbors of TORC1
Neighbors of RA receptor
Neighbors of histone
Neighbors of Rho kinase
Neighbors of PDGF receptor
Neighbors of histone acetyltransferase
Neighbors of adrenoceptor
Neighbors of phosphodiesterase
sars-cov no binding
Figure 3_Mixed network of dexamethasone targets
Figure 3_Mixed network of dexamethasone targets
1_Inflammation in keratinocytes in the pathology of acne
2_Hyperseborrhea in acne vulgaris
2_Acute phase initiation in atopic dermatitis
2_Interleukin-17 and interleukin-22 signaling in psoriasis
1_TNF and IL1B provoke ECM degradation in osteoarthritis
1_Osteoclast-mediated bone resorption in postmenopausal women
2_Osteoblast-mediated bone demineralization
1_Osteoclast functional impairment in osteopetrosis
1_Formation of cysts in polycystic kidney disease
3_The role of interstitial fibroblasts in pyelonephritis
3_Mesangial cell dysfunction in glomerulonephritis
1_Local estrogen production stimulates ectopic endometrium proliferation
3_Enhanced angiogenesis in endometriosis
1_Disruption of luteinizing hormone and follicle-stimulating hormone secretion in PCOS
3_Endoplasmic reticulum stress in age-related macular degeneration
2_Pathogens stimulate mucins expression in the middle ear
2_Cardiomyocyte hypertrophy
3_Dysfunction of smooth muscle cells in hypertension
1_Cigarette smoke causes dysfunction and production of inflammatory mediators in alveolar epithelial cells
3_Role of alveolar macrophages in pulmonary tissue destruction in COPD
3_1_Mucus accumulation in asthma
4_2_Airway smooth muscle cells proliferation and airway tissue remodeling
4_Mucin hyperproduction in goblet and mucous cells in COPD
2_Intestine epithelial cells drive immunological responses in ulcerative colitis
2_CD8+ T-cell response and mucosal damage in celiac disease
6_p12I Viral protein promotes T-cell activation in HTLV-1 infection
3_Human papilloma virus E4 and E5 proteins in viral reproduction
3_1_Beta-cell proliferation and compensation: proliferation
3_Islet beta-cell destruction in T1D
1_Microangiopathy in diabetic neuropathy
drug-target pairs binding
mapk1
New Pathway
Interleukin-17 and interleukin-22 signaling in psoriasis

Group Proteins Involved in Hereditary Breast and Ovarian Cancer Syndrome
Proteins Involved in Cowden Syndrome
other partners for SARS

Source curated
ResNet
GO component

MedScan ID 3725

LocusLink ID 3725
16476
24516
116476
298248
335916
280831

Alias LOC100288387
AH119
LOC100293034
v-jun sarcoma virus 17 oncogene homolog (avian)
c-JUN
Jun
transcription factor c-Jun
LOC100291417
Proto-oncogene C-JUN
v-jun avian sarcoma virus 17 oncogene homolog
OTTMUSP00000008346
proto oncogene proteins c jun
Avian sarcoma virus 17 (v-jun) oncogene homolog
Jun proto-oncogene, AP-1 transcription factor subunit
jun A
Jun oncogene
RP23-135A21.5
AP1_HUMAN
v-jun sarcoma virus 17 oncogene homolog
jun proto-oncogene
Junc
OTTHUMP00000010036
AP1
p39
AP-1
Jun activation domain binding protein
activator protein 1
enhancer-binding protein AP1
transcription factor AP-1
immediate early
Rjg-9
Transcription factor AP I
AP I
activating protein I
activating protein 1
immediate early gene
Ca125
v-jun
c-jun-Ub
similar to v-jun sarcoma virus 17 oncogene homolog; Avian sarcoma virus 17 (v-jun) oncogene homolog
DKEY-86E18.3
c-Jun protein
chromosome
fj36h07
scaffold
wu:fj36h07
zgc:65863

GO ID 0003677
0001228
0003700
0000981
0005096
0071837
0070412
0003723
0001102
0000980
0000978
0035497
0003682
0019899
0046982
0042803
0003713
0008134
0044212
0000976
0031625
0044389
0038095
0007265
0060395
0007568
0001525
0031103
0071276
0071277
0032870
0051365
0034614
0007623
0061029
0035026
0007612
0001889
0051899
0001774
0030224
0043922
0043392
0008285
0043524
0031953
0000122
1990441
0045892
0003151
0043923
0045740
2000144
0070374
0043547
0043065
0045597
0001938
0010634
0048146
0045657
0043525
1902895
0045944
0045893
1904707
0051090
0051726
0001836
0051591
0034097
0042493
0042542
0032496
0009612
0035994
0010033
0009314
0006366
0007179
0005829
0000790
0000228
0005719
0005654
0005634
0035976
0005667
0017053
0033613
0003690
0043565
0009987
0043066
0008284
0048661
0006355
0006351
0071222
0006955
0051091
0014070
0044822
0000982
0003705
0001077
0001190
0007184
0010941
0042127
0005100
0002755
0002756
0035666
0045087
0032321
0051403
0034166
0034134
0034138
0034142
0034146
0034162
0038123
0038124
0002224
0008063
0034130
0003702
0010843
0016563
0016564
0010552
0006350
0046983
0045941
0046332
0005515
0045449
0005622
0000074
0050875
0008270
0008151
0046686
0051597

KEGG ID hsa:3725
mmu:16476
rno:24516

MedLine Reference 11818961
12050152
12791271
12798298
12943993
10428834
10918580
10973489
2825349
9443941
11001927
11597910
11891228
12064606
12145210
12441106
12477932
12743595
12753154
12869527
1310930
14512277
14643899
15314684
15557322
15737994
15797868
15911351
16006965
16087680
16158334
17111371
2113275
2507134
7560090
7721748
8889548
9826657
10022836
10076871
10080190
10087299
10230788
10341238
10349636
10352021
10551403
10728913
10888866
10960769
11042159
11076861
11157052
11217851
11438667
11731234
11779499
11813303
11840290
11867524
11884386
11909859
11909946
11927562
11948401
12034730
12036911
12052899
12119282
12163468
12181357
12215258
12376107
12414794
12441295
12466851
12489182
12532319
12553907
12719996
12756228
12791272
1281302
12815619
12859204
12888549
12929935
12941696
1315307
1351769
1383034
14517347
1459456
14597166
14638681
14638694
14670820
14688262
14757751
14765123
15121835
15135887
15219855
15233917
15256779
15291758
15292661
15302867
15336319
15358865
15375216
15456874
15494506
15522312
15528206
15534203
15541355
15558021
15572149
15572151
15596805
15618518
15626733
15686869
15688012
15708845
15733037
15791649
15795322
15799023
15831482
15840658
15867431
15944151
15944271
15944387
15950217
15961692
16002216
16007074
16049073
1605850
16085472
16123044
16141072
16141073
16148154
16157693
16158333
16163348
16217033
16228289
1631061
16313514
16373341
16373364
16410637
16416088
16473943
16581799
16759155
16785994
16837500
16847049
1684952
1685142
16912279
16973441
17041602
17066317
17074809
17088247
17092936
17108173
1765007
1793595
1887331
1978328
2104845
2108401
2140597
2457172
2574141
2842750
3127828
3136397
3142691
3186736
3422745
7476995
7579389
7601910
7656403
7700631
7705639
7719022
7744871
7748560
7798322
7841657
7862133
7889400
7923577
7929053
7949731
7955078
7989745
8012112
8082881
8088797
8098006
8119710
8123597
8137749
8144618
8150544
8183239
8197114
8208542
8208545
8286110
8308027
8313375
8330736
8344255
8363569
8364887
8369223
8371760
8397366
8415706
8453995
8458421
8479285
8541477
8565820
8637721
8747598
8754282
8777432
8790912
8793856
8798505
8940147
9023306
9047395
9098922
9108083
9108383
9128250
9141200
9154819
9169087
9344659
9356505
9405446
9459310
9524251
9570962
9598328
9858769
9876179
9878062
10026157
10188588
10196196
10220381
10330159
10357819
10421840
10478848
10488148
10490649
10497212
10506225
10509564
10523647
10637231
10644332
10799874
10878360
11022789
11053448
11254713
11260070
11274169
11278277
11278640
11278891
11316804
11331585
11371641
11397794
11432833
11448159
11477071
11551904
11641401
11689449
11704680
11708771
11739718
11801649
11823437
11867732
11877416
11891317
11903046
11912197
11914583
11948398
11956220
11983170
12052862
12077347
12080089
12087103
12091339
12165517
12167088
12183893
12186939
12437352
12446585
12485413
12547826
12554755
12592382
12600818
12615916
12618758
12682910
12692226
12700665
12799614
12805554
12853483
12875982
12909593
12949493
12954631
12963547
12963995
1310896
1448082
14500675
14511403
14522952
14530285
14532268
14645224
14652666
14654548
14667575
14739464
15001576
15034932
15087451
15158360
1516134
15191540
15226448
15249231
15262961
15271374
15302935
15314183
15314185
15333603
15351693
15378002
15383523
15385474
15469925
15480426
15507668
15514030
15528994
15530430
15544846
15550679
15579469
15586248
15642950
15654976
15701643
15702969
15718494
15746191
15863510
15870692
15894171
15897893
15922298
15923621
15923644
15936718
15941782
15991283
15994313
16023596
16055710
16140218
16158054
16199533
16223572
16236267
16243842
16253992
16285957
16289409
16303762
16328781
16341687
16343055
16361535
16380075
16410250
1651323
16569638
16571680
16582099
16620772
16690925
16702224
16786139
16844113
16887814
16895791
16905771
16911523
16928756
16980310
17085440
17097050
17101801
1827203
1922387
2138276
2320002
3194415
7662174
7666555
7690421
7738014
7816143
7823959
7848298
8087846
8108109
8137421
8302594
8380166
8387155
8397339
8440710
8464713
8557686
8570175
8617242
8628277
8649793
8654373
8663380
8663478
8733011
8763994
8798722
8837781
8974016
9129988
9154808
9211894
9223324
9235954
9334186
9346889
9405416
9445037
9468519
9488446
9510247
9545246
9566900
9621077
9628874
9642216
9670954
9671405
9685505
9732876
9786917
9872330
15984772
16033799
16799861
15489334
16586042
16676006
16710414
17009014
17121851
17130130
17215518
17235455
17237388
17237407
17283040
17283046
17314269
17317669
17401435
17403042
17466952
17506864
17510314
17588603
17634427
8662824
10582624
11980884
12376563
16916642
17042795
17145782
17182846
17189700
17244530
17270292
17308994
17341624
17428453
17430897
17442952
17468757
17500068
17554491
17596282
17699753
9447996
16874457
17216194
17503228
9651196
9847304

CellType hepatocyte
squamous cell
hematopoietic cell
transitional epithelial cell
smooth muscle myocyte
endometrial stromal cell
airway epithelial cell
decidual cell
macrophage
trophoblast
pneumocyte
germinal center B-cell
muscle cell
Purkinje cell
neuroglia
epidermis cell
Leydig cell
neuron
ovary follicle cell
kidney tubule cell
exocrine cell
islets of Langerhans
bile duct cells
glandular cells
Hepatocytes
squamous epithelial cells
lymphoid tissue
hematopoietic cells
urothelial cells
smooth muscle cells
cells in endometrial stroma
cells in red pulp
respiratory epithelial cells
cells in white pulp
decidual cells
Macrophages
cells in granular layer
trophoblastic cells
Pneumocytes
cells in molecular layer
germinal center cells
myocytes
Purkinje Cells
cells in seminiferus ducts
non-germinal center cells
glial cells
epidermal cells
Leydig Cells
neuronal cells
cells in glomeruli
follicle cells
cells in tubules
ovarian stroma cells
exocrine glandular cells

Tissue smooth muscle
myocardium
mouth mucosa
skeletal muscles
lymphoid tissue
Pancreas
Liver
epididymis
esophagus
fallopian tube
Adrenal gland
Appendix
tonsil
bone marrow
urinary bladder
breast
uterus, post-menopause
spleen
parathyroid gland
bronchus
Placenta
Lung
Cerebellum
uterus, pre-menopause
stomach, lower
gall bladder
stomach, upper
Prostate
lymph node
heart muscle
vagina
testis
rectum
hippocampus
cerebral cortex
vulva/anal skin
Salivary gland
nasopharynx
thyroid gland
seminal vesicle
oral mucosa
Kidney
cervix, uterine
skeletal muscle
Ovary
Skin
lateral ventricle
colon
small intestine
duodenum

Organism Homo sapiens {Organism urn:agi-taxid:9606}
Mus musculus {Organism urn:agi-taxid:10090}
Rattus norvegicus {Organism urn:agi-taxid:10116}
Homo sapiens
Mus musculus
Rattus norvegicus
Danio rerio
Bos taurus
Human

Mouse chromosome position 4 43.34 cM
4 44.6 cM

OMIM ID 165160
OMIM:165160

Rat chromosome position 5q33
5q34.1

Hugo ID 6204
HGNC:6204

Human chromosome position 1p32.1
1p32-p31

Swiss-Prot Accession P05412
P05412.2
P05627
Q52L79
P05627.3
P17325
P17325.1
Q6FHM7
Q96G93
Q6FHK0
Q3US19
Q3V255
Q6TDG5
JUN_HUMAN
JUN_MOUSE
JUN_RAT
Q52L79_MOUSE

PIR ID A31264
A31345
S12742

GenBank ID NC_000001
NM_002228
NP_002219
NG_047027
AL136985
AY217548
AAO22993
CH471059
EAX06628
CS542415
CAM91157
J04111
AAA59197
KT584072
M23544
U60581
AK307137
BC002646
BC006175
AAH06175
BC009874
AAH09874
BC068522
AAH68522
BG831943
BI793062
BT019759
AAV38564
BU782554
CD370800
CR541724
CAG46525
CR541752
CAG46552
P05412
NC_000070
NM_010591
NP_034721
AL732611
CS693299
CAP12263
U03709
AK132019
BAE20944
AK133722
AK133867
AK135023
BAE22389
AK140911
BAE24518
AK159196
BAE34891
AK159220
AY423853
AAR00344
BC002081
AAH02081
BC021888
AAH21888
BC032086
BC055887
BC094032
AAH94032
BY106462
J04115
AAA37419
X12740
CAA31236
X12761
CAA31252
P05627
NC_005104
NM_021835
NP_068607
AC_000073
AABR07049287
AAHX01038549
CH473998
EDL97766
X17215
CAA35084
BC078738
AAH78738
BE113912
BF414978
CB740532
CK475341
X17163
CAA35041
P17325
NC_018912
AMYH02001100
DQ896432
ABM87431
AC_000026
AAHY01038209
AC_000133
ABBA01074656
AABR06038744
CAC10201
CAM14753
NT_032977
NW_001838579
NW_921351
AC_000044
Q6FHK0
Q6FHM7
NT_039280
NW_001030747
Q3US19
Q3V255
Q52L79
Q6TDG5
NW_001084842
NW_047717
NW_000210
NW_043856
NT_086582
AF227190
51709812
6754401
6754402
12805238
12805239
21284396
21284397
21327814
192577
309169
52762
52763
52758
52759
135299
51458674
44890066
4758616
51460368
27805114
34870044
19923684
11177864
57079
57080
50927568
50927569
57819
57820
135300
27805115
186624
386839
38014305
13544091
13544092
40226266
40226267
46329589
46329590
14179530
15820787
54696383
54696384
23825888
31154890
49456408
49456409
49456462
49456463
135298
12314169
AAF74120
AF227191
AAF74121
8248253
8248254
8248255
8248256
AAH02646
NT_039263
123788411
123792303
37695626
62825871
74149179
74183908
74192749
74204894
81887398
81892901
119627033
123999845
74748524
74748528
33989472
41946923
55251229
62911209
82202287
82228700
AAH56597
AAH65976
AAY21257
BC056597
BC065976
CAH69118
CR392368
DQ003340
NC_007131
NM_199987
NP_956281
NW_001512107
Q4ZJE9
Q6NZT5
115304969
122065248
122132257
3212097
AAC21576
AAI23754
AF069514
BC123753
NC_007301
NW_001494814
O77627
Q08DH1
XM_001249361
XP_001249362
122890215
149044507
XM_216458
XP_216458
BC056597,BC065976
dre:335916
126007383
335916
ZDB-GENE-030131-7859
Dr.1064
41053400
41053401

Swiss-Prot ID JUN_HUMAN
JUN_MOUSE
JUN_RAT
Q52L79_MOUSE

Cell Localization Nucleus
Cytoplasm

Ensembl ID ENSG00000177606
ENSP00000360266.2
ENST00000371222.3
ENSMUSG00000052684
ENSMUSP00000102711.1
ENSMUST00000107094.1
ENSRNOG00000026293
ENSRNOP00000011732.1
ENSRNOT00000011731.3
ENSP00000360266
ENST00000371222
ENSMUSP00000102711
ENSMUST00000107094
ENSRNOP00000011732
ENSRNOT00000011731

MGI ID MGI:96646
96646

RGD ID 2943
69195

Unigene ID Hs.696684
Mm.275071
Rn.93714
Rn.225373
Hs.714791
Hs.723911
Hs.525704
Rn.94975
Hs.78465
Rn.44320
Mm.482
Dr.1064
Bt.11159

Homologene ID 1679

Shape O-vertex

IPI ID IPI00121829
IPI00215370
IPI00008965

Chromosome position 1p32-p31
4 44.6 cM
5q34.1

Microarray ID 1369788_s_at
A_42_P741027
100130_at
1417409_at
1448694_at
msa.4586.0_s_at
x12761_s_at
A_51_P325914
J04111
201464_x_at
89913_s_at
213281_at
201466_s_at
201465_s_at
32583_at
1895_at
aa393106_at
j04111_at
rc_d51060_s_at
A_23_P201538
A_14_P127903
A_14_P134030
A_14_P109617
M339
R560
OR0730
153
OH7608
MB488
1374404_at
1389528_s_at
rc_AA944014_at
rc_AA945867_at
rc_AI175959_at
X17163cds_s_at
222125_Rn
Msa.535.0_at
A_65_P15588
J0247B11-3
NM_010591
33353_at
I_931585

Homo sapiens Chromosome position 1p32-p31

Ensembl Transcript ID ENST00000371222

ENSEMBL ENSG00000177606

FunctionalClass DNA binding
RNA polymerase II transcription factor
double-stranded DNA binding
protein binding
protein heterodimerization
protein homodimerization
sequence-specific DNA binding
transcription factor
transcriptional activator
protein dimerization
transcription factor binding
transcription activator

Hugo Symbol JUN

Bos taurus Chromosome position 3

Mus musculus Chromosome position 4 44.6 cM

KEGG pathway B cell receptor signaling pathway
Colorectal cancer
ErbB signaling pathway
Focal adhesion
GnRH signaling pathway
MAPK signaling pathway
Renal cell carcinoma
T cell receptor signaling pathway
Toll-like receptor signaling pathway
Wnt signaling pathway

State p

Rattus norvegicus Chromosome position 5q34.1

Ensembl Gene ID ENSG00000177606

Keyword transcription factor
nucleus
oncogene
golgi apparatus
bzip transcription factor
RAS small monomeric GTPase
leucine zipper
g protein coupled receptor
acetyltransferase
map kinase kinase
desmoplakin
liposome
DNA binding activity
binding activity
map kinases
basic leucine zipper
factor C
leucine repeat
desmoplakins
SAP kinase
DNA
RNA
nuclei
map kinase
activated blood coagulation factor XIV
JNK

ProteinAtlas NormalTissue Tissue: lateral ventricle; Cell type: glial cells; Level: Low; Expression type: APE; Reliability: High
Tissue: appendix; Cell type: glandular cells; Level: Medium; Expression type: APE; Reliability: High
Tissue: duodenum; Cell type: glandular cells; Level: High; Expression type: APE; Reliability: High
Tissue: tonsil; Cell type: squamous epithelial cells; Level: None; Expression type: APE; Reliability: High
Tissue: pancreas; Cell type: exocrine glandular cells; Level: None; Expression type: APE; Reliability: High
Tissue: small intestine; Cell type: glandular cells; Level: Medium; Expression type: APE; Reliability: High
Tissue: kidney; Cell type: cells in tubules; Level: High; Expression type: APE; Reliability: High
Tissue: breast; Cell type: glandular cells; Level: Medium; Expression type: APE; Reliability: High
Tissue: colon; Cell type: glandular cells; Level: Medium; Expression type: APE; Reliability: High
Tissue: spleen; Cell type: cells in white pulp; Level: None; Expression type: APE; Reliability: High
Tissue: oral mucosa; Cell type: squamous epithelial cells; Level: High; Expression type: APE; Reliability: High
Tissue: skin; Cell type: epidermal cells; Level: Medium; Expression type: APE; Reliability: High
Tissue: adrenal gland; Cell type: glandular cells; Level: Low; Expression type: APE; Reliability: High
Tissue: appendix; Cell type: lymphoid tissue; Level: None; Expression type: APE; Reliability: High
Tissue: bone marrow; Cell type: hematopoietic cells; Level: None; Expression type: APE; Reliability: High
Tissue: bronchus; Cell type: respiratory epithelial cells; Level: Medium; Expression type: APE; Reliability: High
Tissue: cerebellum; Cell type: cells in granular layer; Level: Medium; Expression type: APE; Reliability: High
Tissue: cerebellum; Cell type: cells in molecular layer; Level: None; Expression type: APE; Reliability: High
Tissue: cerebellum; Cell type: Purkinje cells; Level: None; Expression type: APE; Reliability: High
Tissue: cerebral cortex; Cell type: glial cells; Level: Medium; Expression type: APE; Reliability: High
Tissue: cerebral cortex; Cell type: neuronal cells; Level: Low; Expression type: APE; Reliability: High
Tissue: cervix, uterine; Cell type: glandular cells; Level: None; Expression type: APE; Reliability: High
Tissue: cervix, uterine; Cell type: squamous epithelial cells; Level: Medium; Expression type: APE; Reliability: High
Tissue: epididymis; Cell type: glandular cells; Level: Low; Expression type: APE; Reliability: High
Tissue: esophagus; Cell type: squamous epithelial cells; Level: High; Expression type: APE; Reliability: High
Tissue: fallopian tube; Cell type: glandular cells; Level: Medium; Expression type: APE; Reliability: High
Tissue: gall bladder; Cell type: glandular cells; Level: High; Expression type: APE; Reliability: High
Tissue: heart muscle; Cell type: myocytes; Level: None; Expression type: APE; Reliability: High
Tissue: hippocampus; Cell type: glial cells; Level: None; Expression type: APE; Reliability: High
Tissue: hippocampus; Cell type: neuronal cells; Level: None; Expression type: APE; Reliability: High
Tissue: kidney; Cell type: cells in glomeruli; Level: None; Expression type: APE; Reliability: High
Tissue: lateral ventricle; Cell type: neuronal cells; Level: None; Expression type: APE; Reliability: High
Tissue: liver; Cell type: bile duct cells; Level: None; Expression type: APE; Reliability: High
Tissue: liver; Cell type: hepatocytes; Level: None; Expression type: APE; Reliability: High
Tissue: lung; Cell type: macrophages; Level: High; Expression type: APE; Reliability: High
Tissue: lung; Cell type: pneumocytes; Level: Medium; Expression type: APE; Reliability: High
Tissue: lymph node; Cell type: germinal center cells; Level: None; Expression type: APE; Reliability: High
Tissue: lymph node; Cell type: non-germinal center cells; Level: None; Expression type: APE; Reliability: High
Tissue: nasopharynx; Cell type: respiratory epithelial cells; Level: Medium; Expression type: APE; Reliability: High
Tissue: ovary; Cell type: ovarian stroma cells; Level: None; Expression type: APE; Reliability: High
Tissue: pancreas; Cell type: islets of Langerhans; Level: None; Expression type: APE; Reliability: High
Tissue: parathyroid gland; Cell type: glandular cells; Level: None; Expression type: APE; Reliability: High
Tissue: placenta; Cell type: decidual cells; Level: Medium; Expression type: APE; Reliability: High
Tissue: placenta; Cell type: trophoblastic cells; Level: None; Expression type: APE; Reliability: High
Tissue: prostate; Cell type: glandular cells; Level: None; Expression type: APE; Reliability: High
Tissue: rectum; Cell type: glandular cells; Level: Medium; Expression type: APE; Reliability: High
Tissue: salivary gland; Cell type: glandular cells; Level: Low; Expression type: APE; Reliability: High
Tissue: seminal vesicle; Cell type: glandular cells; Level: None; Expression type: APE; Reliability: High
Tissue: skeletal muscle; Cell type: myocytes; Level: Low; Expression type: APE; Reliability: High
Tissue: smooth muscle; Cell type: smooth muscle cells; Level: Low; Expression type: APE; Reliability: High
Tissue: spleen; Cell type: cells in red pulp; Level: None; Expression type: APE; Reliability: High
Tissue: stomach, lower; Cell type: glandular cells; Level: Medium; Expression type: APE; Reliability: High
Tissue: stomach, upper; Cell type: glandular cells; Level: Low; Expression type: APE; Reliability: High
Tissue: testis; Cell type: cells in seminiferus ducts; Level: None; Expression type: APE; Reliability: High
Tissue: testis; Cell type: Leydig cells; Level: None; Expression type: APE; Reliability: High
Tissue: thyroid gland; Cell type: glandular cells; Level: High; Expression type: APE; Reliability: High
Tissue: tonsil; Cell type: germinal center cells; Level: None; Expression type: APE; Reliability: High
Tissue: tonsil; Cell type: non-germinal center cells; Level: None; Expression type: APE; Reliability: High
Tissue: urinary bladder; Cell type: urothelial cells; Level: None; Expression type: APE; Reliability: High
Tissue: uterus, post-menopause; Cell type: cells in endometrial stroma; Level: Low; Expression type: APE; Reliability: High
Tissue: uterus, post-menopause; Cell type: glandular cells; Level: Low; Expression type: APE; Reliability: High
Tissue: uterus, pre-menopause; Cell type: cells in endometrial stroma; Level: Low; Expression type: APE; Reliability: High
Tissue: uterus, pre-menopause; Cell type: glandular cells; Level: None; Expression type: APE; Reliability: High
Tissue: vagina; Cell type: squamous epithelial cells; Level: High; Expression type: APE; Reliability: High
Tissue: vulva/anal skin; Cell type: epidermal cells; Level: High; Expression type: APE; Reliability: High

LocatorString pmquery:curcumin prostate cancer