Protein CCL7

URN urn:agi-llid:6354
Total Entities 0
Connectivity 1088
Name CCL7
Description C-C motif chemokine ligand 7
Notes This gene encodes monocyte chemotactic protein 3, a secreted chemokine which attracts macrophages during inflammation and metastasis. It is a member of the C-C subfamily of chemokines which are characterized by having two adjacent cysteine residues. The protein is an in vivo substrate of matrix metalloproteinase 2, an enzyme which degrades components of the extracellular matrix. This gene is part of a cluster of C-C chemokine family members on chromosome 17q. [provided by RefSeq, Jul 2008]
Primary Cell Localization Extracellular
Class Ligand

Pathway CC Chemokine Receptor Signaling
Mast-Cell Activation via IgE Signaling
Nociception Expression Targets Signaling
CCR1 Expression Targets
Proteins Involved in Atherosclerosis
Proteins Involved in Myocarditis
IL17 Signaling in Psoriasis
Mast-Cell Activation in Asthma
Cytokines Trigger Otitis Media
CCL7 Expression Targets
F2R/F2RL1 -> Expression Targets in Lymphoid System and Blood
2_Interleukin-17 and interleukin-22 signaling in psoriasis
Interleukin-17 and interleukin-22 signaling in psoriasis

Group Genes with Mutations Associated with Crohn's Disease
Chemokines, Growth Factors and Receptors Involved in Cancer Cells Chemotaxis

MedScan ID 6354

LocusLink ID 6354

Alias chemokine (C-C motif) ligand VII
SCYA6
MGC138463
SCYA7
chemotactic protein-3
MGC138465
SY07_HUMAN
CCL7
Monocyte chemotactic protein 3
MCP-3
C-C motif chemokine 7
SY07
fic
CCL7 chemokine
chemokine CCL7
MCP III
Monocyte chemoattractant protein 3
chemotactic protein III
NC28
CC chemokine ligand 7
small inducible cytokine A7
Monocyte chemotactic protein III
MCP IIIs
small inducible cytokine A7 (monocyte chemotactic protein 3)
Monocyte chemoattractant protein III
OTTMUSP00000000787
C-C motif chemokine ligand 7
RP23-350G1.4
MARC
chemokine (C-C motif) ligand 7
CCL-7
MCP3
small-inducible cytokine A7

GO ID 0048020
0031726
0031727
0008009
0008201
0007186
0007267
0006874
0071361
0071346
0071347
0071356
0070098
0006935
0007010
0048245
0006954
0048247
0002548
0030593
0070374
0043547
0030335
2000503
0008360
0010332
0007165
0005623
0005615
0050729
0005576
0006955

KEGG ID hsa:6354

Organism Homo sapiens {Organism urn:agi-taxid:9606}
Homo sapiens

OMIM ID 158106

Hugo ID 10634
HGNC:10634

Human chromosome position 17q12
17q11.2-q12

Swiss-Prot Accession P80098
P80098.3
Q569J6

GenBank ID NC_000017
NM_006273
NP_006264
AC005549
CH471147
EAW80210
X72309
CAB59723
X95070
AF043338
AAC03538
BC070240
BC092436
AAH92436
BC112258
AAI12259
BC112260
AAI12261
CD523198
X71087
CAA50405
CAA50406
CAA50407
P80098
NC_018928
AMYH02033336
HQ258695
ADR83446
AC_000149
ABBA01011212

Swiss-Prot ID CCL7_HUMAN

Cell Localization Secreted

Ensembl ID ENSG00000108688
ENSP00000367832.2
ENST00000378569.2
ENSP00000367832
ENST00000378569

Unigene ID Hs.251526

Shape Rhomb