Protein STAT1

URN urn:agi-llid:6772
Total Entities 0
Connectivity 5078
Name STAT1
Description signal transducer and activator of transcription 1, 91kDa
Notes The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. Two alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]
Primary Cell Localization Nucleus
Class Transcription factor
ObjectType Protein

Pathway Thyroid Hormones Common non-Genomic Effects in Hyperthyroidism
PRL and CSH Action in Mammary Gland
Thrombopoietin Receptors Signaling in Platelet Maturation
Natural Killer Cell Activation
CD8+ T-Cell Activation
T-Cell Cytotoxic Mediated Cell Death
Th1-Cell Differentiation
AHR Signaling in Treg and Dendritic Cells Function
AHR Signaling in Tr1 Cells Function
CXC Chemokine Receptor Signaling
CC Chemokine Receptor Signaling
Plasmin Effects in Inflammation
Basophil Activation
Eosinophil Survival by Cytokine Signaling
Mast-Cell Activation via IgE Signaling
Mast-Cell Activation without Degranulation through CXCR4 Signaling
Mast-Cell Activation without Degranulation
Mast-Cells De Novo Synthesized Mediators via IgE Independent Signaling
Macrophage M1 Lineage
CD16/CD14 Proinflammatory Monocyte Activation
AHR Signaling in M1 Macrophages Function
AXL Receptor Inhibits Macrophages and Dendritic Cells Function
Neutrophil Recruitment and Priming
Vascular Endothelial Cell Activation by Cytokines
Vascular Endothelial Cell Activation by Blood Coagulation Factors
Vascular Endothelial Cell Activation by Growth Factors
Nociception Expression Targets Signaling
CCR1 Expression Targets
IL6 Expression Targets -> Nociception
G0/G1 Phase Transition
Proteins Involved in Atherosclerosis
Th1-Cells Activation and Proliferation in Atherosclerosis
Cardiomyocyte Hypertrophy
Hypertrophic Cardiomyopathy
Endothelial Cell Dysfunction in Pulmonary Hypertension
Proteins Involved in Myocardial Ischemia
Preconditioning Ischemia
Lymphocyte Mediated Myocardial Injury in Myocarditis
SOCS in Negative Feedback Regulation in Myocarditis
Hair Follicle Keratinocyte Apoptosis
Atopic Dermatitis
Melanoma
Apoptosis Block in Melanoma Cell
Proteins Involved in Melanoma
T-Cells Differentiation Block in Psoriasis
IFN-gamma/TNF-alpha Mediated Cell Proliferation in Psoriasis
Dendritic Cell Activation in Systemic Lupus Erythematosis
Proteins Involved in Systemic Lupus Erythematosus
Th1-Cell Function in Systemic Lupus Erythematosus
B-Cell Activation in Systemic Lupus Erythematosus
Vitiligo
T-Cell Cytotoxic Response against Melanocytes in Vitiligo
Plasmacytoid Dendritic Cell in Diabetes Mellitus Type 1
Toll-like Receptors in beta-Cell
Tubular Cell Dysfunction in Progressive Diabetic Nephropathy
Proteins Involved in Diabetic Nephropathy
beta-Cell Destruction through Cytokines in Diabetes Mellitus
beta-Cell Destruction in Diabetes Mellitus Type 1
Nitric Oxide Effects on beta-Cell
Hashimoto's Thyroiditis
Proteins Involved in Hypothyroidism
Proteins Involved in Celiac Disease
CD4+T-Cell Response in Celiac Disease
Metastatic Colorectal Cancer
Th1-Cell Activation in Crohn's Disease
OipA Signaling in Helicobacter Pylori Infection
Proteins Involved in Ulcerative Colitis
B-Cell Acute Lymphoblastic Leukemia
Diffuse Large-B-Cell Lymphoma
Primary Mediastinal B-cell Lymphoma (PMBL) Subtype
Follicular Lymphoma
Proteins Involved in Hodgkin Lymphoma
IL6/IGF1/VEGFA Signaling in Multiple Myeloma
Multiple Myeloma
T-Cell Acute Lymphoblastic Leukemia
Eosinophil Survival in Asthma
Mast-Cell Activation in Asthma
Osteoclast Activation in Gout
Neutrophil Recruitment in Sinovium in Gout
Dendritic Cell Dysfunction in Psoriatic Arthritis
Osteoclast Activation in Psoriatic Arthritis
Keratinocyte Activation in Psoriatic Arthritis
Proteins Involved in Psoriatic Arthritis
Osteoclast Activation in Rheumatoid Arthritis
Skin Fibrosis
CCR5 Signaling in Macrophages
CD4+ T-Cell Death in HIV
Diabetes Induced Periodontitis
Glioblastoma, Primary
Glioblastoma, Secondary
Astrocytoma
IL6/IL12 Signaling Activates Immune System in Multiple Sclerosis
Proteins Involved in Breast Cancer Related to ESR1 Signaling Pathway
Proteins Involved in Breast Cancer Related to ERBB2/VEGFR/Akt Signaling Pathway
Proteins Involved in Breast Cancer Related to IGF1R/Akt Signaling Pathway
Cholesteatoma
Prostate Cancer
RNase L Signaling in Prostate Cancer
Proteins Involved in Prostate Cancer
CDKN2B-AS1 in Epigenetic Regulation of Glaucoma
Aminoglycosides and Cisplatin Induced Ototoxicity (Mouse Model)
Proteins Involved in Hearing Loss
Cytokines Trigger Otitis Media
Proteins Involved in Chronic Obstructive Pulmonary Disease
Polycystins Mutation Effects in Cystic Kidney Disease
Endothelial Cell Dysfunction in Pyelonephritis
AREG -> STAT Expression Targets
Noreadrenaline/Gq Expression Targets
Epinephrine/Gq Expression Targets
Aryl Hydrocarbon Receptor Genomic and non-Genomic Signaling
BTC -> STAT Expression Targets
IFNG -> ARRB1/STAT1 Signaling
CD2 Expression Targets
CD22 -> STAT Expression Targets
CD8 -> NFATC Expression Targets
CD80 -> ATF/CREB/CREBBP Expression Targets
CD86 -> ATF/CREB/CREBBP Expression Targets
CXCL12 Expression Targets
CCL3 Expression Targets
CCL16 Expression Targets
CCL5 Expression Targets
CCL7 Expression Target
CCL15 Expression Targets
CCL2 Expression Targets
IL8 Expression Targets
CSF3 Expression Targets
CSF2 -> STAT Expression Targets
Clozapine Induced Granulocytopenia
EGF -> STAT Expression Targets
EGFR/ERBB -> STAT Signaling
EREG -> STAT Expression Targets
Erythropoietin -> STAT Expression Targets
F2 -> STAT1/NF-kB Expression Targets
PLG -> STAT1/NF-kB Expression Targets
FGF2 -> STAT Expression Targets
FGF10 -> STAT Expression Targets
FGF18 -> STAT Expression Targets
FGF1 -> STAT Expression Targets
FGFR1 -> STAT Signaling
FGFR3 -> STAT Signaling
GH1/GHR -> STAT Expression Targets
CSH1/GHR Expression Targets
CSH1/PRLR Expression Targets
GH1/PRLR Expression Targets
HGF -> STAT Expression Targets
HGFR -> STAT Signaling
Receptors and Adaptor Proteins Activated in Cancer
Proteins with Altered Expression in Cancer-Associated Sustaining of Proliferative Signaling
G0/G1 Cell Cycle Phase Transition Activation in Cancer
N2 Neutrophils in Tumor-Promoting Inflammation and Tumor Progression
VEGF Independent Angiogenesis in Cancer
Myeloid Derived Suppressor Cells in Cancer Immune Escape
IDO1 in Cancer Immune Escape
IGF2 -> STAT Expression Targets
IGF1 -> STAT Expression Targets
Insulin -> STAT Expression Targets
CD2 -> STAT Signaling
InsulinR -> STAT Signaling
IGF1R -> STAT Signaling
IFNLR1-> STAT/NFKB Signaling
IFNW1/IFNR Expression Target
IFNA1/IFNR Expression Targets
IFNB1/IFNR Expression Targets
IFNG/IFNR Expression Targets
IL31R -> STAT Signaling
IL15R -> STAT Signaling
IL10R -> STAT Signaling
IL13R -> STAT Signaling
IL3R -> STAT Signaling
IL27R -> STAT Signaling
IL7R -> STAT Signaling
IL9R -> STAT Signaling
IL5R -> STAT Signaling
IL6R -> STAT Signaling
IL2R -> STAT Signaling
IL12R -> STAT Signaling
IL21R -> STAT Signaling
IL7 Expression Targets
IL13 Expression Targets
IL21 Expression Targets
IL15 Expression Targets
IL12B Expression Targets
IL3 Expression Targets
IL6 Expression Targets
IL10 Expression Targets
IL5 Expression Targets
IL9 Expression Targets
IL31 Expression Targets
IL2 Expression Targets
UrokinaseR -> STAT Signaling
Leptin -> STAT Expression Targets
EGFR-> Expression Targets in Lymphoid System and Blood
NRG1 -> STAT Expression Targets
PTGER4 -> Expression Targets in Nerve Tissue
PDGF -> STAT Expression Targets
PDGFR -> STAT Signaling
CSF2 -> STAT Signaling
KIT -> STAT Signaling
GAST Expression Targets in GAST Expression Targets
CCL11 Expression Targets
AVP/Gq -> STAT Expression Targets
AVP/Gs -> STAT Expression Targets
AGT -> STAT Expression Targets
PRL/PRLR Expression Targets
PRL/GHR -> STAT Expression Targets
ProlactinR -> STAT Signaling
PDCD1 -> STAT Expression Targets
ALK -> STAT Signaling
EphrinR -> STAT Signaling
CSF1 -> STAT Expression Targets
MDK/PTN Expression Targets
KITLG -> STAT Expression Targets
EphrinR Expression Targets
Ras-GAP Regulation Signaling
AXL Receptor Tyrosine Kinase Signaling
EGFR Signaling
TCR -> STAT Expression Targets
T-Cell Receptor -> STAT Signaling
TGFA -> STAT Expression Targets
LTA Expression Targets
TNF -> STAT Expression Targets
TNFRSF1A -> STAT Signaling
Thrombopoietin -> STAT Expression Targets
PLAU -> STAT1 Expression Targets
VEGFA -> STAT Expression Targets
VEGFR -> STAT Signaling
PPAR Psoriasis
pprarg neg, uknown targets, ps-positive
prarg neg,ukn expres targets, ps-positive
PPARG negative targets
pparg expr target_regulators
Neighbors of disease exacerbation
Neighbors of tumor progression
Neighbors of cancer progression
Neighbors of inflammatory status
Neighbors of overall survival
Neighbors of disease severity
Neighbors of tumor size
Neighbors of lesion size
Neighbors of mortality
Neighbors of infarct size
Neighbors of functional recovery
Neighbors of bacterial load
Neighbors of cancer survival
Neighbors of graft survival
Neighbors of lethality
Neighbors of tumor regression
Neighbors of disease-free survival
Neighbors of tumor response
Neighbors of macrophage count
Neighbors of bone mass
Neighbors of tumor recurrence
Neighbors of tumor promotion
Neighbors of morbidity
Neighbors of fibrosis progression
Neighbors of bone mineral density
Neighbors of radioresistance
Neighbors of lesion area
Neighbors of cell density
Neighbors of early mortality
Neighbors of viral load
Neighbors of leukocyte count
Neighbors of cancer risk
Neighbors of tumor aggressiveness
Neighbors of tumor resistance
Neighbors of osteoclast number
Neighbors of cancer recurrence
Neighbors of T-cell count
Neighbors of radiosensitivity
Neighbors of recurrence rate
Neighbors of disease exacerbation
Neighbors of tumor progression
Neighbors of cancer progression
Neighbors of inflammatory status
Neighbors of overall survival
Neighbors of disease severity
Neighbors of tumor size
Neighbors of lesion size
Neighbors of mortality
Neighbors of infarct size
Neighbors of functional recovery
Neighbors of bacterial load
Neighbors of cancer survival
Neighbors of graft survival
Neighbors of lethality
Neighbors of tumor regression
Neighbors of disease-free survival
Neighbors of tumor response
Neighbors of macrophage count
Neighbors of bone mass
Neighbors of tumor recurrence
Neighbors of tumor promotion
Neighbors of morbidity
Neighbors of fibrosis progression
Neighbors of bone mineral density
Neighbors of radioresistance
Neighbors of lesion area
Neighbors of cell density
Neighbors of early mortality
Neighbors of viral load
Neighbors of leukocyte count
Neighbors of cancer risk
Neighbors of tumor aggressiveness
Neighbors of tumor resistance
Neighbors of osteoclast number
Neighbors of cancer recurrence
Neighbors of T-cell count
Neighbors of radiosensitivity
Neighbors of recurrence rate
Neighbors of cell development
Neighbors of immune response
Neighbors of cell population
Neighbors of T-cell development
Neighbors of inflammatory response
Neighbors of wound healing
Neighbors of angiogenesis
Neighbors of innate immune response
Neighbors of cell function
Neighbors of macrophage activation
Neighbors of cell formation
Neighbors of adaptive immune response
Neighbors of osteoclast development
Neighbors of epithelial to mesenchymal transition
Neighbors of immunity
Neighbors of cell proliferative response
Neighbors of chemotaxis
Neighbors of dendritic cell differentiation
Neighbors of cell survival
Neighbors of osteoclast differentiation
Neighbors of cell phenotype
Neighbors of T-cell proliferation
Neighbors of tissue remodeling
Neighbors of cell adhesion
Neighbors of T-cell activation
Neighbors of endothelial cell proliferation
Neighbors of tumor growth
Neighbors of dendritic cell development
Neighbors of tissue repair
Neighbors of cell count
Neighbors of cell infiltration
Neighbors of cell interaction
Neighbors of SMC proliferation
Neighbors of lumen formation
Neighbors of endothelial cell migration
Neighbors of adipogenesis
Neighbors of lipid storage
Neighbors of cell damage
Neighbors of pregnancy
Neighbors of monocyte differentiation
Neighbors of aging
Neighbors of cell motility
Neighbors of bone resorption
Neighbors of monocyte migration
Neighbors of fibroblast proliferation
Neighbors of adipocyte differentiation
Neighbors of macrophage migration
Neighbors of microglial activation
Neighbors of cell migration
Neighbors of cancer growth
Neighbors of stem cell proliferation
Neighbors of smooth muscle cell migration
Neighbors of hepatic regeneration
Neighbors of transendothelial migration
Neighbors of phagocytosis
Neighbors of immune system activation
Neighbors of leukocyte migration
Neighbors of osteoclast formation
Neighbors of cell invasion
Neighbors of hemopoiesis
Neighbors of bone remodeling
Neighbors of ossification
Neighbors of T-cell function
Neighbors of immune system function
Neighbors of autophagy
Neighbors of monocyte adhesion
Neighbors of transcription activation
Neighbors of senescence
Neighbors of T-cell response
Neighbors of tumor immunity
Neighbors of hepatocyte proliferation
Neighbors of cell transdifferentiation
Neighbors of neuronal death
Neighbors of cell growth
Neighbors of ROS generation
Neighbors of epithelial cell proliferation
Neighbors of cancer cell growth
Neighbors of sensitization
Neighbors of hemato-encephalic barrier
Neighbors of macrophage function
Neighbors of cellular immune response
Neighbors of cellular senescence
Neighbors of colony formation
Neighbors of macrophage differentiation
Neighbors of cell differentiation
Neighbors of cell homeostasis
Neighbors of psoriasis
Neighbors of inflammatory disease
Neighbors of rheumatoid arthritis
Neighbors of atherosclerosis
Neighbors of fibrosis
Neighbors of colitis
Neighbors of arthritis
Neighbors of inflammatory bowel disease
Neighbors of injury
Neighbors of metastasis
Neighbors of carcinogenesis
Neighbors of multiple sclerosis
Neighbors of chronic inflammation
Neighbors of inflammation
Neighbors of tumor microenvironment
Neighbors of obesity
Neighbors of diabetes mellitus
Neighbors of asthma
Neighbors of pneumonia
Neighbors of liver fibrosis
Neighbors of chronic obstructive pulmonary disease
Neighbors of myocardial infarction
Neighbors of leukocyte infiltration
Neighbors of reperfusion injury
Neighbors of airway inflammation
Neighbors of hepatitis
Neighbors of insulin resistance
Neighbors of infection
Neighbors of vascular injury
Neighbors of renal injury
Neighbors of macrophage infiltration
Neighbors of liver injury
Neighbors of neuroinflammation
Neighbors of sepsis
Neighbors of death
Neighbors of type 1 diabetes
Neighbors of encephalomyelitis
Neighbors of autoimmune disease
Neighbors of ischemic stroke
Neighbors of dermatitis
Neighbors of neutrophil infiltration
Neighbors of diabetic nephropathy
Neighbors of lung injury
Neighbors of immunopathology
Neighbors of systemic sclerosis
Neighbors of hepatocellular carcinoma
Neighbors of autoimmunity
Neighbors of acute lung injury
Neighbors of gastric cancer
Neighbors of experimental autoimmune encephalomyelitis
Neighbors of colorectal cancer
Neighbors of cardiac remodeling
Neighbors of breast cancer
Neighbors of ischemia
Neighbors of systemic lupus erythematosus
Neighbors of melanoma
Neighbors of collagen-induced arthritis
Neighbors of interstitial fibrosis
Neighbors of kidney disease
Neighbors of heart failure
Neighbors of lung disease
Neighbors of pulmonary fibrosis
Neighbors of cardiovascular disease
Neighbors of stroke
Neighbors of cancer
Neighbors of neoplasm
Neighbors of neointima
Neighbors of vasculitis
Neighbors of atrophy
Neighbors of respiratory hypersensitivity
Neighbors of myocardial fibrosis
Neighbors of synovitis
Neighbors of coronary artery disease
Neighbors of liver disease
Neighbors of prostate cancer
Neighbors of ovarian cancer
Neighbors of pancreatic cancer
Neighbors of hypertension
Neighbors of allograft rejection
Neighbors of macrophage
Neighbors of fibroblast
Neighbors of hepatocyte
Neighbors of endothelial cell
Neighbors of immunocompetent cell
Neighbors of myeloid cell
Neighbors of insulin-secreting cell
Neighbors of T-cell
Neighbors of lung
Neighbors of colorectal region
Neighbors of NF-kB family
Neighbors of Jun/Fos
Neighbors of NFKBI
Neighbors of STAT family
Neighbors of IFNAR ligand
Neighbors of cytokine
Neighbors of interferon
Neighbors of JAK
Neighbors of Ras GTPase
Neighbors of ovalbumin
Neighbors of LXR
Neighbors of lectin
Neighbors of proteasome endopeptidase complex
Neighbors of STAT5
Neighbors of retinoid-X receptor subfamily
Neighbors of ITG
Neighbors of TORC1
Neighbors of RA receptor
Neighbors of histone acetyltransferase
Neighbors of deacetylase
comon ps_pos, pprarg_neg targets
Model of PPARG signaling in psoriasis
PPARG negative regulators and targets
Model of PPARG related pathways in psoriasis (short version)
New Pathway (3)
sars-cov no binding
IFN signaling in alveolar cells
Dendritic Cell Activation in COVID19
Figure 3_Mixed network of dexamethasone targets
Figure 3_Mixed network of dexamethasone targets
1_Differentiation of psoriatic T cells
1_Formation of cysts in polycystic kidney disease
1_Endothelial cells stimulate vasoconstriction and thrombosis in pulmonary hypertension
2_Cardiomyocyte hypertrophy
2_2_Eosinophilia and neutrophilia in asthma: eosinophil apoptosis
4_Inflammatory mediators inhibit GATA signaling in erythropoiesis
1_Antigen-presenting cells promote islet dysfunction and immune system activation in T1D
3_Islet beta-cell destruction in T1D
drug-target pairs direct regulation
drug-target moltransport
Differentiation of psoriatic T cells

Group Genes Associated with Systemic Lupus Erythematosus
other partners for SARS

Source curated
ResNet
GO component

MedScan ID 6772

LocusLink ID 6772
20846
25124
98183
510814
282084
30768

Alias CANDF7
Stat1
Stat I
STAT91
Signal transducer and activator of transcription I
91 kDa signal transducer and activator of transcription I
STAT1 transcription factor
signal transducer and activator of transcription 1, 91kDa
transcription factor components p91/p84
2010005J02Rik
signal transducer and activator of transcription 1, 91kD
Signal transducer and activator of transcription 1-alpha/beta
91 kDa signal transducer and activator of transcription 1
DD6G4-4
transcription factor STAT1
AA408197
OTTHUMP00000165046
PIR:A46159
OTTHUMP00000205845
signal transducer and activator of transcription 1
Transcription factor ISGF-3 components p91/p84
DKFZp686b04100
OTTHUMP00000165047
IMD31A
IMD31B
IMD31C
ISGF-3
hornerin
signal transducer and activator of transcription-1
STAT91s
interferon-dependent positive-acting transcription factor ISGF-3
RIKEN cDNA 1110033K19 gene
transcription factor ISGF III
transcription factor ISGF-3
AV011854
expressed sequence AV011854
1110033K19Rik

GO ID 0031730
0001228
0003700
0000981
0000979
0000978
0045296
0003690
0019899
0035035
0042393
0035257
1990841
0042803
0051721
0070491
0005164
0044389
0007259
0008015
0032869
0035458
0071346
0071407
0019221
0006952
0051607
0043542
0060333
0038114
0070106
0070757
0070102
0038113
0010742
0072162
0072136
0046725
0043124
0016525
0001937
0003340
0072308
0000122
0002230
0045648
0032727
0002053
0051770
0048661
0045944
0007221
0045893
0042981
0042127
0060334
0061326
0051591
0034097
0042542
0035456
0009612
0007584
0043434
0033209
0060337
0016032
0030424
0005737
0005829
0030425
0000790
0005730
0005654
0005634
0048471
0032991
0003677
0043565
0006919
0071345
0071222
0031663
0034240
0008284
0006355
0009617
0042493
0043330
0032496
0034340
0007165
0006351
0006357
0014070
0000983
0000982
0001047
0005509
0005515
0004871
0019048
0006915
0006917
0060397
0006366
0009615
0060338
0007249
0044419
0007260
0010553
0010628
0005062
0006350
0045449
0007262
0009613
0000074
0007242

KEGG ID hsa:6772
rno:25124
mmu:20846

MedLine Reference 11024034
12191995
12477932
12527914
12584205
12960068
1299057
14642652
14678947
14984365
15262323
15590660
15630703
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16616937
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10200816
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15852015
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15919906
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16284791
16315087
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16424049
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16670015
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16688530
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16731906
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16782051
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16843267
16857984
16906167
17032168
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17133483
7490523
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7545930
7567467
7579387
8140422
8530075
8593242
8608597
8608598
8626752
8631837
8675207
8805627
8833906
9022056
9069288
9092506
9119818
9126479
9229117
9287210
9342212
9548487
9638363
9695817
9828143
9846495
9887329
10067896
10358045
10446176
10490649
10506573
10602027
10652206
10692450
10764778
10792030
10805787
10820245
10848577
10848598
10918587
10954736
10961983
10973496
10982844
11152457
11226159
11238845
11248027
11257227
11278462
11278865
11294897
11301323
11418623
11452125
11722592
11752148
11777927
11804954
11815625
11835405
11839738
11843291
11886859
11909852
11909970
11927559
11932384
11981818
12039028
12048190
12070153
12130529
12161037
12165521
12191570
12223098
12232802
12356736
12388709
12426389
12459177
12539042
12590259
12610144
12629155
12634403
12637327
12722480
12734330
12748293
12759242
12777975
12788789
12804771
12807916
12817007
12846741
12855573
12855578
12856330
12867595
12917439
12923054
12948935
12963127
12967644
14500749
14557668
14599788
14623896
14654078
14654702
14674010
14688135
14690454
14702039
14746803
14751560
14755057
14963018
1496401
14976049
15010467
1502203
15055356
15123634
15165826
15210729
15217838
15221897
15280488
15284024
15467722
15494521
15604419
15650219
15703780
15778351
15780933
15795279
15824515
15825084
15919942
15979846
15996661
15998520
16148108
16189514
16195225
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16236267
16254375
16257975
16260419
16318585
16388135
16467883
16481475
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16511123
16512786
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16572323
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16585190
16628196
16773129
16799645
16897667
16918696
16934001
16935931
16940534
16951379
17030574
17075845
17145596
17182865
7514165
7543024
7657660
7690989
7885841
8232552
8549654
8621447
8631962
8943351
8986769
9135145
9205132
9284918
9344858
9355737
9373149
9373245
9452495
9484840
9584171
9630226
9724754
9804857
9843502
9880553
9925928
9989503
12419823
10702714
11442634
15140960
15489334
16306601
16878149
16904741
16978698
17227821
17237409
17266440
17287281
17346710
17371985
17386941
17442890
17486072
17490620
17523873
17538964
17804871
8125298
10754318
11034357
11310846
12223448
12444163
12872135
15972639
16301649
16563502
16689660
17065231
17121994
17200147
17227866
17229692
17234735
17237438
17293456
17307940
17424888
17473223
17475277
17507688
17513775
17533179
17549733
17634555
17689680
10188224
15350851
15454281
15749807
16269269
17116388
17251186
17293493
7519422
9144559

Organism Homo sapiens {Organism urn:agi-taxid:9606}
Mus musculus {Organism urn:agi-taxid:10090}
Rattus norvegicus {Organism urn:agi-taxid:10116}
Homo sapiens
Mus musculus
Rattus norvegicus
Bos taurus
Danio rerio

Mouse chromosome position 1 26.81 cM
1 25.9 cM

OMIM ID 600555
614892
614162
613796
209950

Rat chromosome position 9q22
9q31-q32

Hugo ID 11362
HGNC:11362

Human chromosome position 2q32.2

Swiss-Prot Accession P42224
P42224.2
A0A087WSP5
Q8C8M3
Q8CFQ1
Q8C3V4
Q99K94
Q8C497
P42225.1
Q6P6Q7
F1M9D6
Q9QXK0
A8K989
B2RCA0
D2KFR8
D3DPI7
Q53S88
Q53XW4
Q68D00
Q9UDL5
J3KPM9
P42225
Q67C41
Q3TW11
Q3V3D6
Q91Y52
Q9D323
O70406
Q7TP57
STAT1_HUMAN
B2RCA0_HUMAN
Q53XW4_HUMAN
Q68D00_HUMAN
Q6P6Q7_RAT
Q8C3V4_MOUSE
Q99K94_MOUSE

PIR ID A46159

GenBank ID NC_000002
XR_001738915
XR_001738914
XM_017004783
XP_016860272
NM_007315
NP_009330
XM_006712718
XP_006712781
NM_139266
NP_644671
NG_008294
AC067945
AAY24183
AH008323
AAF04559
AX354554
CAD22974
AY366464
AAR13284
AY865620
AAW56072
CH471058
EAX10850
EAX10851
EAX10852
EAX10853
EAX10854
EAX10855
CS542449
CAM91174
CS542451
CAM91175
HQ284032
U18662
U18663
U18664
U18665
U18666
U18667
U18668
U18669
U18670
AI992149
AK096686
AK225853
AK292604
BAF85293
AK315002
BAG37497
BC002704
AAH02704
BC141921
AAI41922
BG699050
BT007241
AAP35905
BU738296
BX400908
CN410740
CR749636
CAH18430
CR998778
DA313984
EB385742
GU211347
ADA59516
GU211348
ADA59517
M97935
AAB64012
M97936
P42224
NC_000067
NM_009283
NP_033309
NM_001205314
NP_001192243
XM_006495811
XP_006495874
NM_001205313
NP_001192242
XM_017319464
XP_017174953
XM_017319463
XP_017174952
NM_001357627
AC123752
AF349678
AAK48844
CH466548
EDK99964
EDK99965
EDK99966
EDK99967
EDK99968
U80267
AK008127
AK018544
BAB31265
AK039458
BAC30355
AK041599
BAE43313
AK041814
BAE43314
AK046517
BAC32766
AK082706
BAC38579
AK084855
BAC39293
AK088874
AK157263
BAE34017
AK157458
AK159887
BAE35456
BC004808
AAH04808
BC042551
AAH42551
BC057690
BX513160
U06924
AAA19454
P42225
NC_005108
NM_032612
NP_116001
NM_001034164
NP_001029336
AC_000077
AABR07067607
AABR07073481
AAHX01059848
AAHX01059849
AC094675
CH473965
EDL99092
AA901120
AF034252
AF053767
AAC08438
AF205604
AAF20200
BC062079
AAH62079
BM386875
CF109416
CV075250
DY564252
FQ227362
FQ231334
FQ232551
ABBA01062392
XM_006495812
XM_006495813
XM_005246815
XM_005246816
EU832073
AAHY01006307
AAHY01006306
XP_005246872
XP_005246873
AMYH02005442
AC_000023
XP_006495876
XP_006495875
AC_000134
ACE86735
NC_018913
AF182311
ACE87421
AABR06060248
AABR06060249
AABR06060250
AF182314
EU831980
NT_005403
NW_921585
NW_001838863
AC_000045
CR601119
CR618286
Q67C41
NT_039170
NW_001030680
Q3TW11
Q3V3D6
Q8C3V4
Q8C497
Q8C8M3
Q8CFQ1
Q91Y52
Q99K94
Q9D323
NW_047815
NW_001084882
O70406
Q6P6Q7
Q7TP57
Q9QXK0
Q53XW4
Q9UDL5
Q68D00
AAH57690
Q6PF86
AABR03068246
Q53S88
U92116
AW214029
AA960121
AAC02821
NW_000166
BM239586
2996209
38304005
6636498
81861373
81869420
81885263
1174458
123781007
123783857
12858298
13435936
13898647
26333275
26338161
26349879
26351313
27502700
34785478
458710
74178727
74183076
74186815
74204784
81871537
81876394
81876464
81878027
81880102
81881308
81892594
81899350
AA408197
119631255
119631256
119631257
119631260
12803735
2281071
2507413
30583321
38194550
51476968
57790280
62988796
74708726
74724461
74725554
74726678
74727062
NT_086633
122131798
154426144
45385786
AAI51379
AAS59770
AY488117
BC151378
NC_007300
NW_001494645
Q05FF2
XM_001253473
XP_001253474
3687402
38173885
82071168
82186677
94733815
AAH60933
AJ005692
BC045863
BC060933
BX548072
CAA06676
CAK11455
NC_007133
NM_131480
NP_571555
NW_001512391
O93598
Q6P943
119631258
119631259
148667548
148667549
148667550
148667551
148667552
149046199

Swiss-Prot ID STAT1_HUMAN
Q8CFQ1_MOUSE
Q9QXK0_RAT
Q6P6Q7_RAT
Q8C3V4_MOUSE
Q99K94_MOUSE
B2RCA0_HUMAN
Q53XW4_HUMAN
Q68D00_HUMAN
D3DPI7_HUMAN

Cell Localization Cytoplasm
Nucleus

Ensembl ID ENSG00000115415
ENSP00000354394.3
ENST00000361099.7
ENSP00000376136.3
ENST00000392322.7
ENST00000540176.5
ENSMUSG00000026104
ENSMUSP00000141132.1
ENSMUST00000186057.6
ENSMUSP00000140875.1
ENSMUST00000186857.6
ENSMUSP00000066743.7
ENSMUST00000070968.13
ENSMUSP00000140518.1
ENSMUST00000186574.6
ENSRNOG00000014079
ENSRNOP00000019465.6
ENSRNOT00000019465.7
ENSRNOP00000019465
ENSRNOT00000019465
ENSP00000376136
ENST00000392322
ENSP00000376137
ENSMUSP00000141132
ENST00000392323
ENSMUSP00000066743
ENSMUSP00000140518
ENSMUST00000070968
ENSMUST00000186057
ENSMUST00000186574
ENSP00000354394
ENSMUST00000186857
ENST00000361099
ENSMUSP00000140875

MGI ID MGI:103063
103063
2138078

RGD ID 3771

Unigene ID Hs.642990
Mm.277406
Rn.33229
Hs.743244
Mm.487336
Hs.715518
Hs.724418
Hs.708051
Hs.470943
Hs.651258
Bt.33292
Dr.120105
Hs.699271

Homologene ID 21428

Shape O-vertex

IPI ID IPI00030781
IPI00218188
IPI00956843
IPI00213245
IPI00655247
IPI00467004
IPI00795482
IPI00797149
IPI00652052
IPI00626843
IPI00382229

Microarray ID 101465_at
AFFX-HUMISGF3A/M97935_MA_at
AFFX-HUMISGF3A/M97935_5_at
200887_s_at
AFFX-HUMISGF3A/M97935_3_at

Homo sapiens Chromosome position 2q32.2

Ensembl Transcript ID ENST00000361099
ENST00000409465
ENST00000392323
ENST00000392322

ENSEMBL ENSG00000115415

FunctionalClass hematopoietin/interferon-class (D200-domain) cytokine receptor signal transducer
protein binding
transcription factor
DNA binding
calcium ion binding
signal transducer

Bos taurus Chromosome position 2

Mus musculus Chromosome position 1 25.9 cM
1

KEGG pathway Jak-STAT signaling pathway

ProteinAtlas SubcellularLocation Main location: Nucleus but not nucleoli;Cytoplasm; Other location: ; Expression type: APE; Reliability: High

Rattus norvegicus Chromosome position 9q31-q32

Ensembl Gene ID ENSG00000115415
LRG_111

ProteinAtlas NormalTissue Tissue: gall bladder; Cell type: glandular cells; Level: Low; Expression type: APE; Reliability: Low
Tissue: lateral ventricle; Cell type: glial cells; Level: None; Expression type: APE; Reliability: Low
Tissue: lung; Cell type: pneumocytes; Level: None; Expression type: APE; Reliability: Low
Tissue: appendix; Cell type: lymphoid tissue; Level: Medium; Expression type: APE; Reliability: Low
Tissue: cerebellum; Cell type: cells in molecular layer; Level: None; Expression type: APE; Reliability: Low
Tissue: stomach
upper; Cell type: glandular cells; Level: Low; Expression type: APE; Reliability: Low
Tissue: tonsil; Cell type: squamous epithelial cells; Level: Medium; Expression type: APE; Reliability: Low
Tissue: vagina; Cell type: squamous epithelial cells; Level: None; Expression type: APE; Reliability: Low
Tissue: ovary; Cell type: ovarian stroma cells; Level: None; Expression type: APE; Reliability: Low
Tissue: placenta; Cell type: trophoblastic cells; Level: Low; Expression type: APE; Reliability: Low
Tissue: skin; Cell type: epidermal cells; Level: None; Expression type: APE; Reliability: Low
Tissue: kidney; Cell type: cells in tubules; Level: Medium; Expression type: APE; Reliability: Low
Tissue: adrenal gland; Cell type: glandular cells; Level: None; Expression type: APE; Reliability: Low
Tissue: cervix
uterine; Cell type: squamous epithelial cells; Level: Low; Expression type: APE; Reliability: Low
Tissue: spleen; Cell type: cells in white pulp; Level: Medium; Expression type: APE; Reliability: Low
Tissue: urinary bladder; Cell type: urothelial cells; Level: Medium; Expression type: APE; Reliability: Low
Tissue: skeletal muscle; Cell type: myocytes; Level: None; Expression type: APE; Reliability: Low
Tissue: appendix; Cell type: glandular cells; Level: Low; Expression type: APE; Reliability: Low
Tissue: bone marrow; Cell type: hematopoietic cells; Level: Medium; Expression type: APE; Reliability: Low
Tissue: breast; Cell type: glandular cells; Level: Low; Expression type: APE; Reliability: Low
Tissue: bronchus; Cell type: respiratory epithelial cells; Level: Low; Expression type: APE; Reliability: Low
Tissue: cerebellum; Cell type: cells in granular layer; Level: None; Expression type: APE; Reliability: Low
Tissue: cerebellum; Cell type: Purkinje cells; Level: None; Expression type: APE; Reliability: Low
Tissue: cerebral cortex; Cell type: glial cells; Level: None; Expression type: APE; Reliability: Low
Tissue: cerebral cortex; Cell type: neuronal cells; Level: None; Expression type: APE; Reliability: Low
Tissue: cervix, uterine; Cell type: glandular cells; Level: None; Expression type: APE; Reliability: Low
Tissue: cervix, uterine; Cell type: squamous epithelial cells; Level: Low; Expression type: APE; Reliability: Low
Tissue: colon; Cell type: glandular cells; Level: Low; Expression type: APE; Reliability: Low
Tissue: duodenum; Cell type: glandular cells; Level: Low; Expression type: APE; Reliability: Low
Tissue: epididymis; Cell type: glandular cells; Level: Low; Expression type: APE; Reliability: Low
Tissue: esophagus; Cell type: squamous epithelial cells; Level: Low; Expression type: APE; Reliability: Low
Tissue: fallopian tube; Cell type: glandular cells; Level: None; Expression type: APE; Reliability: Low
Tissue: heart muscle; Cell type: myocytes; Level: None; Expression type: APE; Reliability: Low
Tissue: hippocampus; Cell type: glial cells; Level: None; Expression type: APE; Reliability: Low
Tissue: hippocampus; Cell type: neuronal cells; Level: None; Expression type: APE; Reliability: Low
Tissue: kidney; Cell type: cells in glomeruli; Level: Low; Expression type: APE; Reliability: Low
Tissue: lateral ventricle; Cell type: neuronal cells; Level: None; Expression type: APE; Reliability: Low
Tissue: liver; Cell type: bile duct cells; Level: None; Expression type: APE; Reliability: Low
Tissue: liver; Cell type: hepatocytes; Level: None; Expression type: APE; Reliability: Low
Tissue: lung; Cell type: macrophages; Level: Medium; Expression type: APE; Reliability: Low
Tissue: lymph node; Cell type: germinal center cells; Level: Medium; Expression type: APE; Reliability: Low
Tissue: lymph node; Cell type: non-germinal center cells; Level: Medium; Expression type: APE; Reliability: Low
Tissue: nasopharynx; Cell type: respiratory epithelial cells; Level: Low; Expression type: APE; Reliability: Low
Tissue: oral mucosa; Cell type: squamous epithelial cells; Level: Medium; Expression type: APE; Reliability: Low
Tissue: ovary; Cell type: follicle cells; Level: None; Expression type: APE; Reliability: Low
Tissue: pancreas; Cell type: exocrine glandular cells; Level: Low; Expression type: APE; Reliability: Low
Tissue: pancreas; Cell type: islets of Langerhans; Level: Low; Expression type: APE; Reliability: Low
Tissue: parathyroid gland; Cell type: glandular cells; Level: None; Expression type: APE; Reliability: Low
Tissue: placenta; Cell type: decidual cells; Level: Low; Expression type: APE; Reliability: Low
Tissue: prostate; Cell type: glandular cells; Level: Medium; Expression type: APE; Reliability: Low
Tissue: rectum; Cell type: glandular cells; Level: Low; Expression type: APE; Reliability: Low
Tissue: salivary gland; Cell type: glandular cells; Level: None; Expression type: APE; Reliability: Low
Tissue: seminal vesicle; Cell type: glandular cells; Level: None; Expression type: APE; Reliability: Low
Tissue: small intestine; Cell type: glandular cells; Level: Low; Expression type: APE; Reliability: Low
Tissue: smooth muscle; Cell type: smooth muscle cells; Level: None; Expression type: APE; Reliability: Low
Tissue: spleen; Cell type: cells in red pulp; Level: Medium; Expression type: APE; Reliability: Low
Tissue: stomach, lower; Cell type: glandular cells; Level: Low; Expression type: APE; Reliability: Low
Tissue: stomach, upper; Cell type: glandular cells; Level: Low; Expression type: APE; Reliability: Low
Tissue: testis; Cell type: cells in seminiferus ducts; Level: Low; Expression type: APE; Reliability: Low
Tissue: testis; Cell type: Leydig cells; Level: None; Expression type: APE; Reliability: Low
Tissue: thyroid gland; Cell type: glandular cells; Level: Low; Expression type: APE; Reliability: Low
Tissue: tonsil; Cell type: germinal center cells; Level: Low; Expression type: APE; Reliability: Low
Tissue: tonsil; Cell type: non-germinal center cells; Level: Low; Expression type: APE; Reliability: Low
Tissue: uterus, post-menopause; Cell type: cells in endometrial stroma; Level: None; Expression type: APE; Reliability: Low
Tissue: uterus, post-menopause; Cell type: glandular cells; Level: None; Expression type: APE; Reliability: Low
Tissue: uterus, pre-menopause; Cell type: cells in endometrial stroma; Level: None; Expression type: APE; Reliability: Low
Tissue: uterus, pre-menopause; Cell type: glandular cells; Level: Low; Expression type: APE; Reliability: Low
Tissue: vulva/anal skin; Cell type: epidermal cells; Level: Low; Expression type: APE; Reliability: Low

LocatorString gscquery:achondroplasia
pmftq:achondroplasia