Pathway
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Thrombopoietin Receptors Signaling in Platelet Maturation
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CD8+ T-Cell Activation
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Th1-Cell Differentiation
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AHR Signaling in Th17 Cells Function
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Th17-Cell Differentiation
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Plasmin Effects in Inflammation
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AHR in Intestinal Cell Antimicrobial Barrier Maintenance
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Mast-Cell Activation without Degranulation
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anti-Inflammatory Function of Macrophage M2 Lineage
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AXL Receptor Inhibits Macrophages and Dendritic Cells Function
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Positive Acute Phase Proteins Synthesis
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Vascular Endothelial Cell Activation by Cytokines
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Vascular Endothelial Cell Activation by Blood Coagulation Factors
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Vascular Endothelial Cell Activation by Growth Factors
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IL6 Expression Targets -> Nociception
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Th1-Cells Activation and Proliferation in Atherosclerosis
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Lymphocyte Mediated Myocardial Injury in Myocarditis
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SOCS in Negative Feedback Regulation in Myocarditis
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Atopic Dermatitis
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T-Cells Differentiation Block in Psoriasis
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IL22 Induces Keratinocyte Proliferation in Psoriasis
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Dendritic Cell Activation in Systemic Lupus Erythematosis
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Th17-Cell Function in Systemic Lupus Erythematosus
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Th1-Cell Function in Systemic Lupus Erythematosus
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B-Cell Activation in Systemic Lupus Erythematosus
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Vitiligo
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T-Cell Cytotoxic Response against Melanocytes in Vitiligo
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Humoral Immunity in Vitiligo
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Toll-like Receptors in beta-Cell
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Adipokines and Cytokines in Insulin Resistance in Skeletal Muscles
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CD4+T-Cell Response in Celiac Disease
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Th1-Cell Activation in Crohn's Disease
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Th17-Cell Activation in Crohn's Disease
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Genes with Susceptibility for Crohn's Disease and Ulcerative Colitis
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Leukocyte Migration toward the Endothelial Cell in Ulcerative Colitis
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IL6/IGF1/VEGFA Signaling in Multiple Myeloma
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Multiple Myeloma
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Eosinophil Survival in Asthma
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Il17 Signaling Related Neutrophilia in Asthma
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Periostin (POSTN) Production by Airway Epithelium in Asthma
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Airway Smooth Muscle Cell High Rate Proliferation
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Goblet-Cell Related Mucus Secretion in Asthma
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Club-Cell Role in Asthma
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Th17-Cell Differentiation in Asthma
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Mucin Production in Goblet Airway Epithelial Cells
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Dendritic Cell Dysfunction in Psoriatic Arthritis
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Th17-Cell and Th1 Immune Responsein Psoriatic Arthritis
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Keratinocyte Activation in Psoriatic Arthritis
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B-Cells Function in Systemic Scleroderma
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Th17-Cell Numbers Reduction in HIV
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Diabetes Induced Periodontitis
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Genes with Mutations Associated with Psoriatic Arthritis
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Glioma Invasion Signaling
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IL6/IL12 Signaling Activates Immune System in Multiple Sclerosis
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Proteins Involved in Endometriosis
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IL6/JAK/STAT3 Signaling in Cholesteatoma
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Cholesteatoma
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Neurotrophic Factor Deprivation in Retinal Ganglion Cell Death
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Cytokines Trigger Otitis Media
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Mucin Hyperproduction in Goblet and Mucous Cells
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CLCF1 Expression Targets
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CTF1 Expression Targets
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CSF3 Expression Targets
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LIF Expression Targets
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CNTF Expression Targets
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F2 -> STAT1/NF-kB Expression Targets
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PLG -> STAT1/NF-kB Expression Targets
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GH2/GHR Expression Target
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GH1/GHR -> STAT Expression Targets
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CSH1/GHR Expression Targets
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Receptors and Adaptor Proteins Activated in Cancer
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STAT3 and NFkB Activate Inflammation-Induced Tumorigenesis
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IL23A and IL17A Provoke Cancer-Associated Inflammation
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STAT3 Inhibits Maturation of Dendritic Cells and Facilitates Cancer Progression
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STAT3 Facilitates the Function of Treg Cells and Cancer Progression
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IL12 Antitumor Effect is Blocked in Cancer
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IL13/STAT6/ZEB1 Signalling Promotes Cancer Metastatic Progression
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N2 Neutrophils in Tumor-Promoting Inflammation and Tumor Progression
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IDO1 in Cancer Immune Escape
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IFNLR1-> STAT/NFKB Signaling
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IFNW1/IFNR Expression Target
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IFNA1/IFNR Expression Targets
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IFNB1/IFNR Expression Targets
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IL22R -> STAT3 Signaling
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IL10R -> STAT Signaling
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IL13R -> STAT Signaling
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IL6R -> STAT Signaling
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IL12R -> STAT Signaling
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IL12R -> NF-kB/NFATC Signaling
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IL13 Expression Targets
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IL12B Expression Targets
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IL6 Expression Targets
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IL10 Expression Targets
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IL22 Expression Targets
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UrokinaseR -> ELK/SRF Signaling
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UrokinaseR -> STAT Signaling
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OSM/IL6ST/LIFR Expression Targets
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CSF2 -> STAT Signaling
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PRL/GHR -> STAT Expression Targets
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CSF1 -> STAT Expression Targets
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PAF Expression Targets
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Thrombopoietin -> STAT Expression Targets
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PLAU -> STAT1 Expression Targets
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PLAU -> ELK-SRF/AP-1 Expression Targets
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VEGFA -> STAT Expression Targets
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VEGFR -> STAT Signaling
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PPAR Psoriasis
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Model of PPARG signaling in psoriasis
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New Pathway (3)
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dsRNA induces innate immunity and INFs in alveolar cells
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IFN signaling in alveolar cells
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Dendritic Cell Activation in COVID19
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1_Differentiation of psoriatic T cells
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2_Interleukin-17 and interleukin-22 signaling in psoriasis
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2_The role of endothelial cells in pyelonephritis
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3_Role of neurotrophic factor deprivation in retinal ganglion cell death
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3_2_Regulation of airway surface liquid (ASL) thickness
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3_1_Mucus accumulation in asthma
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2_2_Eosinophilia and neutrophilia in asthma: eosinophil apoptosis
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4_Mucin hyperproduction in goblet and mucous cells in COPD
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1_Defects in response to pathogens in the gut promotes inflammation in Crohn's disease
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3_Leukocyte migration toward the endothelial cells in the intestine microvasculature
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4_1_Polymorphisms associated with inflammatory bowel diseases
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1_Antigen-presenting cells promote islet dysfunction and immune system activation in T1D
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2_Defective tolerance of autoreactive T-cell in T1D
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Differentiation of psoriatic T cells
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Interleukin-17 and interleukin-22 signaling in psoriasis
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