Pathway
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mTOR Signaling Activation by Fatty Acids and Glucose
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Hypoxia Inhibits mTOR Signaling
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Protein Oxidation and Aggregation in Aging
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AMPK Related Catabolism Deceleration in Glucose Insufficiency
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Lipoxin A4/FPR2-Related Neutrophil Depression
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Neutrophil Activation via LTB4/Polyisoprenyl Phosphate Signaling
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Eosinophil Activation
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Macrophage M1 Lineage
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CD16/CD14 Proinflammatory Monocyte Activation
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Vascular Endothelial Cell Activation by NO
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GFs/TNF -> Ion Channels
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Nociception Expression Targets Signaling
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EDNRA/B -> Vascular Motility
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ADRA1A -> IL6 Production
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ADRA1 -> Prostaglandin Generation
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BDKRB1/2 -> Prostaglandin Generation
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HTR1 -> IL6 Production
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HTR5 -> TNF Production
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HTR1 -> Membrane Transport
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Scavenger Receptor OLR1 in Inflammation Related Endothelial Dysfunction
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Dilated Cardiomyopathy
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Neurons Necrosis Caused by Energy Deficiency
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Apoptotic Keratinocytes Clearance Recession in Systemic Lupus Erythematosus
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Oxidative Stress in Vitiligo
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Vitiligo
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Toll-like Receptors in beta-Cell
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beta-Cell Death in Diabetes Mellitus Type 2
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beta-Cell Recovery in Diabetes Mellitus
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Hyperglycemia and Hyperlipidemia Trigger beta-Cell Apoptosis
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Fatty Acids in Hypertension and Atherosclerosis Development
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Eosinophil Activation and Degranulation in Asthma
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CFTR Facilitates Oxidative Stress in Airway Epithelium in CF
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Airway Epithelial Cell Dysfunction
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Ca2+ Overload in Muscular Dystrophies
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Muscular Dystrophies
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Dystrophin Glycoprotein Complex Signaling in Muscular Dystrophies
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Neurotoxin Effects in Parkinson's Disease
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Brain Cell Necrosis in Vascular Dementia
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Oxidative Stress, All-Trans-Retinal and Lipofuscin Toxicity in AMD
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Alveolar Macrophages Dysfunction in COPD
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Neutrophil Associated Lung Damage in Chronic Obstructive Pulmonary Disease
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Penile Detumescense Augmentation Mechanisms
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Advanced Glycation End Products in Diabetes or Age Related Erectile Dysfunction
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Proteins with Altered Expression in Erectile Dysfunction
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Proteins Involved in Erectile Dysfunction
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Doxorubicin Induced Cardiotoxicity
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Cyclosporine Induced Nephrotoxicity
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ROS Metabolism
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EGFR Transactivation in Cancer and Non-Cancer Cells
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Asbestosis- and Silicosis-Associated Inflammation Provokes Cancer Development
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Oxidized LDL/OLR1 Activates Cell Proliferation in Cancer
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Respiratory Chain Impairment in Cancer
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AGT -> TP53 Expression Targets
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AGT -> CREB Expression Targets
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AGT -> ELK/SRF Expression Targets
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TNF-alpha/TNFRSF1A Signaling
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Ras Signaling
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HIF1 Signaling
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PI3K/RAC1 Signaling
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ROS in Neutrophil Mediated Cell Damage
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ROS in Triggering Vascular Inflammation
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ROS and RNS in Vasoconstriction and Vasodilation Regulation
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Ca2+ Cytosolic Overload
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ROS in Angiotensin Mediated Cardiovascular Remodeling and Hypertrophy
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prarg neg,ukn expres targets, ps-positive
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Neighbors of NAD(P)H oxidase
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comon ps_pos, pprarg_neg targets
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Model of PPARG signaling in psoriasis
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PPARG negative regulators and targets
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2_Chondrocyte death in osteoarthritis
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2_Podocyte dysfunction in glomerulonephritis
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2_Oxidative stress, all-trans-retinal, and lipofuscin toxicity in agerelated macular degeneration
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1_Low-density lipoprotein internalization and the accumulation of lipids in atherosclerosis
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1_Endothelial cells stimulate vasoconstriction and thrombosis in pulmonary hypertension
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2_Hyperglycemia and hyperlipidemia trigger beta-cell apoptosis
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3_2_Beta-cell proliferation and compensation: neogenesis/dedifferentiation
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3_Pain perception in diabetic neuropathy
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2_Neuron and Schwann cell death
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