Pathway
|
NOD-like Receptors
|
|
Th1-Cell Differentiation
|
|
Th17-Cell Differentiation
|
|
Toll-like Receptor Independent Sterile Inflammation
|
|
Lipids Enhance Apoptotic Cell Engulfment and Reduce Inflammation
|
|
Basophil Activation
|
|
Mast-Cells De Novo Synthesized Mediators via IgE Independent Signaling
|
|
Proteins Involved in Atherosclerosis
|
|
Th1-Cells Activation and Proliferation in Atherosclerosis
|
|
Proteins Involved in Myocardial Ischemia
|
|
Lymphocyte Mediated Myocardial Injury in Myocarditis
|
|
Proteins Involved in Myocarditis
|
|
Proteins Involved in Acne Vulgaris
|
|
Proteins Involved in Atopic Dermatitis
|
|
Proteins Involved in Psoriasis
|
|
T-Cells Differentiation Block in Psoriasis
|
|
Apoptotic Keratinocytes Clearance Recession in Systemic Lupus Erythematosus
|
|
Dendritic Cell Activation in Systemic Lupus Erythematosis
|
|
Proteins Involved in Systemic Lupus Erythematosus
|
|
Th17-Cell Function in Systemic Lupus Erythematosus
|
|
T-Cell Cytotoxic Response against Melanocytes in Vitiligo
|
|
Plasmacytoid Dendritic Cell in Diabetes Mellitus Type 1
|
|
Proteins Involved in Diabetes Mellitus Type 1
|
|
Conventional Dendritic Cell Role in Diabetes Mellitus Type 1
|
|
Proteins Involved in Diabetic Nephropathy
|
|
Proteins Involved in Insulin Resistance
|
|
Proteins Involved in non-Alcoholic Fatty Liver Disease
|
|
Hashimoto's Thyroiditis
|
|
Proteins Involved in Obesity
|
|
CD4+T-Cell Response in Celiac Disease
|
|
Th1-Cell Activation in Crohn's Disease
|
|
Macrophage Dysfunction
|
|
Proteins Involved in Inflammatory Bowel Diseases
|
|
Proteins Involved in Helicobacter Infections
|
|
Dendritic Cell Function in Ulcerative Colitis
|
|
Antigen-Presenting Cell Role in Asthma
|
|
Th17-Cell Differentiation in Asthma
|
|
Proteins Involved in Osteoarthritis
|
|
Proteins Involved in Polycystic Ovary Syndrome
|
|
Dendritic Cell Dysfunction in Psoriatic Arthritis
|
|
Th17-Cell and Th1 Immune Responsein Psoriatic Arthritis
|
|
Synovial Fibroblast Activation by Citokines in Rheumatoid Arthritis
|
|
Proteins Involved in Rheumatoid Arthritis
|
|
Th17-Cell Numbers Reduction in HIV
|
|
Proteins Involved in Periodontitis
|
|
PAPA Syndrome
|
|
Mevalonate Kinase Deficiency
|
|
Cryopyrin (NLPR3) Associated Periodic Syndromes
|
|
Familial Mediterranean Fever
|
|
Proteins Involved in Glioma
|
|
Proteins Involved in Neuroblastoma
|
|
Proteins Involved in Multiple Sclerosis
|
|
Proteins Involved in Endometriosis
|
|
Proteins Involved in Spontaneous Abortion
|
|
Proteins Involved in Age-Related Macular Degeneration
|
|
Immune System Role in Otitis Media
|
|
Alveolar Macrophage Negative Regulation Declined in COPD
|
|
Alveolar Macrophages Dysfunction in COPD
|
|
Proteins Involved in Chronic Obstructive Pulmonary Disease
|
|
T-Cell Cytotoxic Activation
|
|
Proteins Involved in Pulmonary Emphysema
|
|
Proteins Involved in Glomerulonephritis
|
|
Asbestosis- and Silicosis-Associated Inflammation Provokes Cancer Development
|
|
Proteins with Altered Expression in Tumor-Promoting Inflammation
|
|
Proteins/Ions Transporters -> Expression Targets in Lymphoid System and Blood
|
|
GPCRs Family -> Expression Targets in Lymphoid System and Blood
|
|
Elevated Receptors -> Expression Targets in Thymus
|
|
P2RX7 -> Expression Targets in Nerve Tissue
|
|
TGFB1-TGFBR1 Expression Targets
|
|
e
|
|
pathway 4
|
|
PPAR Psoriasis
|
|
pprarg neg, uknown targets, ps-positive
|
|
prarg neg,ukn expres targets, ps-positive
|
|
PPARG negative targets
|
|
pparg expr target_regulators
|
|
Neighbors of disease exacerbation
|
|
Neighbors of tumor progression
|
|
Neighbors of cancer progression
|
|
Neighbors of inflammatory status
|
|
Neighbors of overall survival
|
|
Neighbors of disease severity
|
|
Neighbors of tumor size
|
|
Neighbors of lesion size
|
|
Neighbors of mortality
|
|
Neighbors of survival rate
|
|
Neighbors of infarct size
|
|
Neighbors of survival time
|
|
Neighbors of functional recovery
|
|
Neighbors of insulin sensitivity
|
|
Neighbors of bacterial load
|
|
Neighbors of graft survival
|
|
Neighbors of therapeutic efficacy
|
|
Neighbors of clinical stage
|
|
Neighbors of lethality
|
|
Neighbors of tumor regression
|
|
Neighbors of recurrence-free survival
|
|
Neighbors of disease-free survival
|
|
Neighbors of tumor response
|
|
Neighbors of treatment outcome
|
|
Neighbors of body weight
|
|
Neighbors of body weight gain
|
|
Neighbors of cardiovascular risk
|
|
Neighbors of microvessel density
|
|
Neighbors of tumor promotion
|
|
Neighbors of neutrophil count
|
|
Neighbors of glucose tolerance
|
|
Neighbors of morbidity
|
|
Neighbors of mortality rate
|
|
Neighbors of fat mass
|
|
Neighbors of adverse outcome
|
|
Neighbors of radioresistance
|
|
Neighbors of lesion area
|
|
Neighbors of progression-free survival
|
|
Neighbors of viral load
|
|
Neighbors of blood pressure
|
|
Neighbors of leukocyte count
|
|
Neighbors of vascular reactivity
|
|
Neighbors of vascular leakage
|
|
Neighbors of body mass index
|
|
Neighbors of tumor aggressiveness
|
|
Neighbors of systolic blood pressure
|
|
Neighbors of blood glucose
|
|
Neighbors of ejection fraction
|
|
Neighbors of median survival
|
|
Neighbors of fasting plasma glucose
|
|
Neighbors of T-cell count
|
|
Neighbors of antimetastatic activity
|
|
Neighbors of energy expenditure
|
|
Neighbors of vascular tone
|
|
Neighbors of breast cancer risk
|
|
Neighbors of functional status
|
|
Neighbors of neurological outcome
|
|
Neighbors of pathological response
|
|
Neighbors of lymphocyte count
|
|
Neighbors of monocyte count
|
|
Neighbors of comorbidity
|
|
Neighbors of carotid intima-media thickness
|
|
Neighbors of fibroblast phenotype
|
|
Neighbors of fractional shortening
|
|
Neighbors of disease exacerbation
|
|
Neighbors of tumor progression
|
|
Neighbors of cancer progression
|
|
Neighbors of inflammatory status
|
|
Neighbors of overall survival
|
|
Neighbors of disease severity
|
|
Neighbors of tumor size
|
|
Neighbors of lesion size
|
|
Neighbors of mortality
|
|
Neighbors of survival rate
|
|
Neighbors of infarct size
|
|
Neighbors of survival time
|
|
Neighbors of functional recovery
|
|
Neighbors of insulin sensitivity
|
|
Neighbors of bacterial load
|
|
Neighbors of graft survival
|
|
Neighbors of therapeutic efficacy
|
|
Neighbors of clinical stage
|
|
Neighbors of lethality
|
|
Neighbors of tumor regression
|
|
Neighbors of recurrence-free survival
|
|
Neighbors of disease-free survival
|
|
Neighbors of tumor response
|
|
Neighbors of treatment outcome
|
|
Neighbors of body weight
|
|
Neighbors of body weight gain
|
|
Neighbors of cardiovascular risk
|
|
Neighbors of microvessel density
|
|
Neighbors of tumor promotion
|
|
Neighbors of neutrophil count
|
|
Neighbors of glucose tolerance
|
|
Neighbors of morbidity
|
|
Neighbors of mortality rate
|
|
Neighbors of fat mass
|
|
Neighbors of adverse outcome
|
|
Neighbors of radioresistance
|
|
Neighbors of lesion area
|
|
Neighbors of progression-free survival
|
|
Neighbors of viral load
|
|
Neighbors of blood pressure
|
|
Neighbors of leukocyte count
|
|
Neighbors of vascular reactivity
|
|
Neighbors of vascular leakage
|
|
Neighbors of body mass index
|
|
Neighbors of tumor aggressiveness
|
|
Neighbors of systolic blood pressure
|
|
Neighbors of blood glucose
|
|
Neighbors of ejection fraction
|
|
Neighbors of median survival
|
|
Neighbors of fasting plasma glucose
|
|
Neighbors of T-cell count
|
|
Neighbors of antimetastatic activity
|
|
Neighbors of energy expenditure
|
|
Neighbors of vascular tone
|
|
Neighbors of breast cancer risk
|
|
Neighbors of functional status
|
|
Neighbors of neurological outcome
|
|
Neighbors of pathological response
|
|
Neighbors of lymphocyte count
|
|
Neighbors of monocyte count
|
|
Neighbors of comorbidity
|
|
Neighbors of carotid intima-media thickness
|
|
Neighbors of fibroblast phenotype
|
|
Neighbors of fractional shortening
|
|
Neighbors of cell development
|
|
Neighbors of immune response
|
|
Neighbors of cell population
|
|
Neighbors of T-cell development
|
|
Neighbors of inflammatory response
|
|
Neighbors of wound healing
|
|
Neighbors of angiogenesis
|
|
Neighbors of innate immune response
|
|
Neighbors of cell function
|
|
Neighbors of macrophage activation
|
|
Neighbors of cell formation
|
|
Neighbors of adaptive immune response
|
|
Neighbors of osteoclast development
|
|
Neighbors of epithelial to mesenchymal transition
|
|
Neighbors of immunity
|
|
Neighbors of cell proliferative response
|
|
Neighbors of chemotaxis
|
|
Neighbors of dendritic cell differentiation
|
|
Neighbors of cell survival
|
|
Neighbors of osteoclast differentiation
|
|
Neighbors of cell phenotype
|
|
Neighbors of T-cell proliferation
|
|
Neighbors of tissue remodeling
|
|
Neighbors of cell adhesion
|
|
Neighbors of T-cell activation
|
|
Neighbors of endothelial cell proliferation
|
|
Neighbors of tumor growth
|
|
Neighbors of dendritic cell development
|
|
Neighbors of tissue repair
|
|
Neighbors of cell count
|
|
Neighbors of cell infiltration
|
|
Neighbors of cell interaction
|
|
Neighbors of SMC proliferation
|
|
Neighbors of lumen formation
|
|
Neighbors of endothelial cell migration
|
|
Neighbors of adipogenesis
|
|
Neighbors of lipid storage
|
|
Neighbors of cell damage
|
|
Neighbors of pregnancy
|
|
Neighbors of monocyte differentiation
|
|
Neighbors of aging
|
|
Neighbors of cell motility
|
|
Neighbors of bone resorption
|
|
Neighbors of monocyte migration
|
|
Neighbors of fibroblast proliferation
|
|
Neighbors of macrophage migration
|
|
Neighbors of microglial activation
|
|
Neighbors of neutrophil recruitment
|
|
Neighbors of regeneration
|
|
Neighbors of cell migration
|
|
Neighbors of cancer growth
|
|
Neighbors of stem cell proliferation
|
|
Neighbors of smooth muscle cell migration
|
|
Neighbors of hepatic regeneration
|
|
Neighbors of transendothelial migration
|
|
Neighbors of phagocytosis
|
|
Neighbors of immune system activation
|
|
Neighbors of leukocyte migration
|
|
Neighbors of leukocyte recruitment
|
|
Neighbors of osteoclast formation
|
|
Neighbors of monocyte recruitment
|
|
Neighbors of cell invasion
|
|
Neighbors of heart function
|
|
Neighbors of bone remodeling
|
|
Neighbors of ossification
|
|
Neighbors of T-cell function
|
|
Neighbors of immune system function
|
|
Neighbors of lung development
|
|
Neighbors of autophagy
|
|
Neighbors of monocyte adhesion
|
|
Neighbors of senescence
|
|
Neighbors of T-cell response
|
|
Neighbors of tumor immunity
|
|
Neighbors of hepatocyte proliferation
|
|
Neighbors of cell transdifferentiation
|
|
Neighbors of stem cell differentiation
|
|
Neighbors of endothelial cell function
|
|
Neighbors of neuronal death
|
|
Neighbors of cell growth
|
|
Neighbors of ROS generation
|
|
Neighbors of epithelial cell proliferation
|
|
Neighbors of first trimester pregnancy
|
|
Neighbors of sensitization
|
|
Neighbors of hemato-encephalic barrier
|
|
Neighbors of macrophage function
|
|
Neighbors of cellular immune response
|
|
Neighbors of colony formation
|
|
Neighbors of cell differentiation
|
|
Neighbors of life span
|
|
Neighbors of cell homeostasis
|
|
Neighbors of psoriasis
|
|
Neighbors of inflammatory disease
|
|
Neighbors of rheumatoid arthritis
|
|
Neighbors of atherosclerosis
|
|
Neighbors of fibrosis
|
|
Neighbors of colitis
|
|
Neighbors of arthritis
|
|
Neighbors of inflammatory bowel disease
|
|
Neighbors of injury
|
|
Neighbors of atherogenesis
|
|
Neighbors of vascular remodeling
|
|
Neighbors of metastasis
|
|
Neighbors of carcinogenesis
|
|
Neighbors of multiple sclerosis
|
|
Neighbors of chronic inflammation
|
|
Neighbors of inflammation
|
|
Neighbors of tumor microenvironment
|
|
Neighbors of pathological angiogenesis
|
|
Neighbors of obesity
|
|
Neighbors of vascular disease
|
|
Neighbors of diabetes mellitus
|
|
Neighbors of asthma
|
|
Neighbors of pneumonia
|
|
Neighbors of hyperplasia
|
|
Neighbors of osteoarthritis
|
|
Neighbors of liver fibrosis
|
|
Neighbors of chronic obstructive pulmonary disease
|
|
Neighbors of myocardial infarction
|
|
Neighbors of leukocyte infiltration
|
|
Neighbors of reperfusion injury
|
|
Neighbors of airway inflammation
|
|
Neighbors of hepatitis
|
|
Neighbors of insulin resistance
|
|
Neighbors of infection
|
|
Neighbors of vascular injury
|
|
Neighbors of renal injury
|
|
Neighbors of preeclampsia
|
|
Neighbors of macrophage infiltration
|
|
Neighbors of liver injury
|
|
Neighbors of neuroinflammation
|
|
Neighbors of sepsis
|
|
Neighbors of death
|
|
Neighbors of type 1 diabetes
|
|
Neighbors of encephalomyelitis
|
|
Neighbors of autoimmune disease
|
|
Neighbors of ischemic stroke
|
|
Neighbors of dermatitis
|
|
Neighbors of neutrophil infiltration
|
|
Neighbors of heart disease
|
|
Neighbors of diabetic nephropathy
|
|
Neighbors of lung injury
|
|
Neighbors of immunopathology
|
|
Neighbors of systemic sclerosis
|
|
Neighbors of hepatocellular carcinoma
|
|
Neighbors of autoimmunity
|
|
Neighbors of acute lung injury
|
|
Neighbors of gastric cancer
|
|
Neighbors of atherosclerotic plaque
|
|
Neighbors of experimental autoimmune encephalomyelitis
|
|
Neighbors of colorectal cancer
|
|
Neighbors of cardiac remodeling
|
|
Neighbors of breast cancer
|
|
Neighbors of ischemia
|
|
Neighbors of systemic lupus erythematosus
|
|
Neighbors of melanoma
|
|
Neighbors of collagen-induced arthritis
|
|
Neighbors of cartilage degeneration
|
|
Neighbors of interstitial fibrosis
|
|
Neighbors of neoplasm invasion
|
|
Neighbors of kidney disease
|
|
Neighbors of heart failure
|
|
Neighbors of lung disease
|
|
Neighbors of pulmonary fibrosis
|
|
Neighbors of cardiovascular disease
|
|
Neighbors of stroke
|
|
Neighbors of cancer
|
|
Neighbors of cerebral ischemia
|
|
Neighbors of type 2 diabetes
|
|
Neighbors of neoplasm
|
|
Neighbors of endometriosis
|
|
Neighbors of neointima
|
|
Neighbors of vasculitis
|
|
Neighbors of atrophy
|
|
Neighbors of diet-induced obesity
|
|
Neighbors of respiratory hypersensitivity
|
|
Neighbors of myocardial fibrosis
|
|
Neighbors of synovitis
|
|
Neighbors of coronary artery disease
|
|
Neighbors of rupture
|
|
Neighbors of endothelial cell dysfunction
|
|
Neighbors of liver disease
|
|
Neighbors of prostate cancer
|
|
Neighbors of hypertrophy
|
|
Neighbors of osteolysis
|
|
Neighbors of ovarian cancer
|
|
Neighbors of pancreatic cancer
|
|
Neighbors of hypertension
|
|
Neighbors of intimal hyperplasia
|
|
Neighbors of allograft rejection
|
|
Neighbors of proteinuria
|
|
Neighbors of epithelial cell
|
|
Neighbors of keratinocyte
|
|
Neighbors of vascular smooth muscle cell
|
|
Neighbors of umbilical vein endothelial cell
|
|
Neighbors of monocyte
|
|
Neighbors of alveolar macrophage
|
|
Neighbors of synoviocyte
|
|
Neighbors of macrophage
|
|
Neighbors of adipocyte
|
|
Neighbors of activated monocyte
|
|
Neighbors of fibroblast
|
|
Neighbors of airway epithelial cell
|
|
Neighbors of PBMC
|
|
Neighbors of stromal cell
|
|
Neighbors of osteoblast
|
|
Neighbors of pneumocyte
|
|
Neighbors of endometrium cell
|
|
Neighbors of microglia
|
|
Neighbors of trophoblast
|
|
Neighbors of intestine epithelium cell
|
|
Neighbors of mononuclear cell
|
|
Neighbors of hepatocyte
|
|
Neighbors of kidney mesangial cell
|
|
Neighbors of endothelial cell
|
|
Neighbors of dendritic cell
|
|
Neighbors of Kuppfer cell
|
|
Neighbors of proadipocyte
|
|
Neighbors of kidney tubule cell
|
|
Neighbors of inflammatory cell
|
|
Neighbors of bone marrow macrophage
|
|
Neighbors of peritoneal macrophage
|
|
Neighbors of osteoclast
|
|
Neighbors of neutrophil
|
|
Neighbors of smooth muscle myocyte
|
|
Neighbors of astrocyte
|
|
Neighbors of bone marrow derived dendritic cell
|
|
Neighbors of activated T-cell
|
|
Neighbors of mesothelial cell
|
|
Neighbors of mononuclear phagocyte
|
|
Neighbors of immunocompetent cell
|
|
Neighbors of granulocyte
|
|
Neighbors of cardiac myocyte
|
|
Neighbors of myeloid cell
|
|
Neighbors of mesenchymal stroma cell
|
|
Neighbors of stem cell
|
|
Neighbors of tumor infiltrating macrophage
|
|
Neighbors of sinusoidal cell
|
|
Neighbors of B-cell
|
|
Neighbors of leukocyte
|
|
Neighbors of chondrocyte
|
|
Neighbors of insulin-secreting cell
|
|
Neighbors of T-cell
|
|
Neighbors of M1 macrophage
|
|
Neighbors of mast cell
|
|
Neighbors of spleen cell
|
|
Neighbors of neuroglia
|
|
Neighbors of hematopoietic cell
|
|
Neighbors of adipose macrophage
|
|
Neighbors of podocyte
|
|
Neighbors of mammary epithelial cell
|
|
Neighbors of conventional dendritic cell
|
|
Neighbors of antigen-presenting cell
|
|
Neighbors of epidermis cell
|
|
Neighbors of phagocyte
|
|
Neighbors of kidney cell
|
|
Neighbors of lymphocyte
|
|
Neighbors of Langerhans cell
|
|
Neighbors of thymic epithelial cell
|
|
Neighbors of brain cell
|
|
Neighbors of M2 macrophage
|
|
Neighbors of peritoneum cell
|
|
Neighbors of lymphoid cell
|
|
Neighbors of blood cell
|
|
Neighbors of skin cell
|
|
Neighbors of lymph node cell
|
|
Neighbors of lung
|
|
Neighbors of liver
|
|
Neighbors of kidney
|
|
Neighbors of skin
|
|
Neighbors of intestine
|
|
Neighbors of lymph node
|
|
Neighbors of colon
|
|
Neighbors of airway
|
|
Neighbors of blood vessel
|
|
Neighbors of heart
|
|
Neighbors of aorta
|
|
Neighbors of gastrointestinal tract
|
|
Neighbors of bone
|
|
Neighbors of placenta
|
|
Neighbors of carotid artery
|
|
Neighbors of synovial membrane
|
|
Neighbors of esophagus
|
|
Neighbors of periodontium
|
|
Neighbors of retina
|
|
Neighbors of brain
|
|
Neighbors of breast
|
|
Neighbors of blood vessel wall
|
|
Neighbors of stomach
|
|
Neighbors of islets of Langerhans
|
|
Neighbors of cardiovascular system
|
|
Neighbors of pancreas
|
|
Neighbors of prostate
|
|
Neighbors of central nervous system
|
|
Neighbors of kidney glomerulus
|
|
Neighbors of immune system
|
|
Neighbors of spleen
|
|
Neighbors of peritoneum
|
|
Neighbors of left ventricle
|
|
Neighbors of omentum
|
|
Neighbors of vein
|
|
Neighbors of glands
|
|
Neighbors of hippocampus
|
|
Neighbors of cerebral cortex
|
|
Neighbors of nervous system
|
|
Neighbors of nasopharynx
|
|
Neighbors of salivary gland
|
|
Neighbors of ileum
|
|
Neighbors of aggregated lymphoid follicle of small intestine
|
|
Neighbors of NF-kB family
|
|
Neighbors of oxidized LDL
|
|
Neighbors of JNK
|
|
Neighbors of PPAR
|
|
Neighbors of Jun/Fos
|
|
Neighbors of PKC
|
|
Neighbors of PI3K
|
|
Neighbors of STAT family
|
|
Neighbors of mitogen-activated protein kinase
|
|
Neighbors of IFNAR ligand
|
|
Neighbors of TLR
|
|
Neighbors of JAK
|
|
Neighbors of PKA
|
|
Neighbors of beta adrenoceptor
|
|
Neighbors of IKBK
|
|
Neighbors of adipokine
|
|
Neighbors of IgG
|
|
Neighbors of LXR
|
|
Neighbors of p38
|
|
Neighbors of IL23
|
|
Neighbors of PDGF-BB
|
|
Neighbors of IL12
|
|
Neighbors of prostaglandin-endoperoxide synthase
|
|
Neighbors of heat shock protein 90
|
|
Neighbors of lectin
|
|
Neighbors of Ang II receptor
|
|
Neighbors of superoxide dismutase
|
|
Neighbors of proteasome endopeptidase complex
|
|
Neighbors of class nuclear receptor with C4 zinc fingers
|
|
Neighbors of WNT
|
|
Neighbors of immunoglobulin
|
|
Neighbors of PP2B
|
|
Neighbors of ITG
|
|
Neighbors of relaxin
|
|
Neighbors of histone
|
|
Neighbors of Rho kinase
|
|
Neighbors of caspase
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Model of PPARG signaling in psoriasis
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PPARG negative regulators and targets
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Model of PPARG related pathways in psoriasis (short version)
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dsRNA induces innate immunity and INFs in alveolar cells
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Dendritic Cell Activation in COVID19
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Overview. Diseases of the skin (chapter 11)
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1_Differentiation of psoriatic T cells
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1_Insufficient activation of immune response in the middle ear epithelium cells in otitis media
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3_Role of alveolar macrophages in pulmonary tissue destruction in COPD
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1_Th2 cell response in asthma
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1_Defects in response to pathogens in the gut promotes inflammation in Crohn's disease
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2_Intestine epithelial cells drive immunological responses in ulcerative colitis
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4_1_Polymorphisms associated with inflammatory bowel diseases
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2_Lipotoxicity in NAFLD
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1_Antigen-presenting cells promote islet dysfunction and immune system activation in T1D
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2_Defective tolerance of autoreactive T-cell in T1D
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Figure 4_Diabetes mellitus Type 1: conventional dendritic cell
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drug-target moltransport
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Differentiation of psoriatic T cells
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