Pathway
|
Longevity Related Drugs
|
|
Oxidative Stress in Amyotrophic Lateral Sclerosis
|
|
Alzheimer's Disease
|
|
Skin Aging
|
|
High Level of Homocystine Effects (Methylation Cycle)
|
|
Melatonin Effects on Circadian Cycle
|
|
Autophagic-Lysosomal System Decline Associated with Aging
|
|
Fatty Acids Cause Oxidative Stress and Mitochondria Decline in Aging
|
|
Protein Oxidation and Aggregation in Aging
|
|
Necrosis
|
|
Positive Acute Phase Proteins Synthesis
|
|
Melatonin in Cell Survival and Antioxidant Response
|
|
Reperfusion Injury in Myocardial ischemia
|
|
Renin-Angiotensin-Aldosterone System in Myocardial ischemia
|
|
NO Synthesis in Early Vasospasm
|
|
Apoptotic Keratinocytes Clearance Recession in Systemic Lupus Erythematosus
|
|
Vitiligo
|
|
Humoral Immunity in Vitiligo
|
|
Macrophage Function in Diabetes Mellitus Type 1
|
|
beta-Cell Death in Diabetes Mellitus Type 2
|
|
Polyol Pathway in Diabetic Microangiopathy
|
|
Peripheral Tissue Microangiopathy
|
|
Tubular Cell Dysfunction in Progressive Diabetic Nephropathy
|
|
Oxidative Stress in Diabetic Neuropathy
|
|
AGE Related Insulin Resistance in Skeletal Muscles
|
|
Lipid Metabolism Impairement in non-Alcoholic Fatty Liver Disease
|
|
beta-Cell Recovery in Diabetes Mellitus
|
|
Hashimoto's Thyroiditis Triggers
|
|
Macrophage Dysfunction
|
|
Genes with Susceptibility for Crohn's Disease and Ulcerative Colitis
|
|
SERPINA1 Associated Pulmonary Emphysema
|
|
Club-Cell Role in Asthma
|
|
CFTR Facilitates Oxidative Stress in Airway Epithelium in CF
|
|
Airway Epithelial Cell Dysfunction
|
|
PPARGC1A Repression in Huntington Disease
|
|
Glutamate Toxiicity Effects on Striatum Medium Spiny Neurons in Hantington's Disease
|
|
Oxytocin Signaling in Brain Nerve Cell (Hypothesis)
|
|
Gluten Impact on Neuronal System (Hypothesis)
|
|
beta-Casomorphins/Opioid Receptors Affect Brain Function (Hypothesis)
|
|
Ca2+ Overload in Muscular Dystrophies
|
|
Muscular Dystrophies
|
|
Dystrophin Glycoprotein Complex Signaling in Muscular Dystrophies
|
|
Muscular Dystrophy, Facioscapulohumeral
|
|
Mitochondrial Dysfunction in Alzheimer's Disease
|
|
Estrogen Effects in Mitochondria in Alzheimer Disease
|
|
APP and Glutamate Signaling Cause Neuronal Dysfunction in Alzheimer Disease
|
|
Mitochondrial Respiratory Chain Dysfunction
|
|
APP Processing in Alzheimer Disease
|
|
Tricarboxylic Acid Cycle Enzymes Involvement in Alzheimer Disease
|
|
Metals and Amyloid beta Toxicity in Alzheimer's Disease
|
|
Ca2+ Toxicity in Neurons
|
|
PARK7 and LRRK2 in Young Onset Parkinson's Disease
|
|
Neurotoxin Effects in Parkinson's Disease
|
|
SNCA in Young Onset Parkinson's Disease
|
|
SOD1 Mutation
|
|
Glutamate Mediated Excitotoxicity in Amyotrophic Lateral Sclerosis
|
|
FOXL2 Mutation in Ovarian Dysgenesis
|
|
Oxidative Stress, All-Trans-Retinal and Lipofuscin Toxicity in AMD
|
|
TLR3 Role in Retinal Pigment Epithelial Cell
|
|
Alveolar Epithelial Cell Dysfunction in COPD
|
|
Podocyte Dysfunction in Glomerulonephritis
|
|
Hyperammonemia Type I
|
|
Citrullinemia Type I
|
|
Argininemia
|
|
Ammonia Effects on Brain Cells
|
|
Citrullinemia Type II
|
|
Argininosuccinic Aciduria in Urea Cycle Disorders
|
|
Hyperammonemia Type II
|
|
Cyclosporine Induced Nephrotoxicity
|
|
Glutamine in Cancer Metabolism
|
|
Mutations in Krebs Cycle Enzymes in Cancer
|
|
Tumor Infiltrating Macrophages in Cancer Progression and Immune Escape
|
|
EZH2 Methyltransferase Role in Cancer
|
|
FOXO1 Signaling
|
|
Glutamate Mediated Neurotoxicity
|
|
Oxidative Stress Protection via AHR-NFE2L2-NQO1 Signaling in Keratinocytes
|
|
New Pathway (1)
|
|
PPARG inhibits phenotypes assotiated with psoriasis
|
|
efects selected
|
|
2_Podocyte dysfunction in glomerulonephritis
|
|
2_Oxidative stress, all-trans-retinal, and lipofuscin toxicity in agerelated macular degeneration
|
|
1_Cigarette smoke causes dysfunction and production of inflammatory mediators in alveolar epithelial cells
|
|
2_Hyperglycemia and hyperlipidemia trigger beta-cell apoptosis
|
|
3_2_Beta-cell proliferation and compensation: neogenesis/dedifferentiation
|
|
2_Ion channel CFTR failure in cystic fibrosis airway epithelium (class III-IV mutations)
|
|
1_Microangiopathy in diabetic neuropathy
|
|
1_Glutamate and calcium excitotoxicity of motor neurons in ALS
|
|
2_Mutations in SOD1 and associated proteins cause motor neuron death in familial ALS
|
|
1_ab_Amyloid-beta in Alzheimer's disease
|