Pathway
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Proteins Involved in Stem Cell Exhaustion in Aging
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Longevity Related Drugs
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Proteins with Altered Expression in Aging
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Oncogene Induced Cellular Senescence
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DNA Persistent Repair Inhibits mTOR Signaling
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mTOR Signaling Activation by Fatty Acids and Glucose
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mTOR Signaling Activation by Amino Acids
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mTOR Signaling
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mTOR Signaling Hyperfunction
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Hypoxia Inhibits mTOR Signaling
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SIRT1 Signaling in Aging
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Autophagic-Lysosomal System Decline Associated with Aging
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mTOR Signaling Activation by Taste Sensor Receptors (Rodent Model)
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MTOR/TP53 Regulates Cell Metabolism
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A-cell (X-like): Ghrelin and Nesfatin-1 Synthesis
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Insulin Influence on Protein Synthesis
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Insulin Signaling
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Synaptic Potentiation by PKMZ in LTP Maintenance - Active State
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SCF/FBXW7 Complex
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SCF/BTRC Complex
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Proteins Involved in Dilated Cardiomyopathy
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Proteins Involved in Hypertrophic Cardiomyopathy
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Cardiomyocyte Hypertrophy
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Hypertrophic Cardiomyopathy
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Proteins Involved in Arterial Hypertension
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Smooth Muscle Cell Dysfunction in Arterial Hypertension
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TRPM4/6/7/8 Signaling in Arterial Hypertension (Hypothesis)
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Myocardial Remodeling
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Myocardial Infarction
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Proteins Involved in Myocardial Ischemia
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Preconditioning Ischemia
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Cell Cycle Dysregulation in Melanoma
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Melanoma
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Proteins Involved in Melanoma
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IL22 Induces Keratinocyte Proliferation in Psoriasis
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Th0-Cell Aberrant Activation in Systemic Lupus Erythematosus
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Th1-Cell Function in Systemic Lupus Erythematosus
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Th2-Cell Function in Systemic Lupus Erythematosus
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Proteins Involved in Diabetes Mellitus Type 2
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Donohue Syndrome Progression (Hypothesis)
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Proteins Involved in Diabetic Nephropathy
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Mesangial Cell Dysfunction in Diabetic Nephropathy
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Glucocorticoids in Insulin Resistance in Skeletal Muscles
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Proteins Involved in Insulin Resistance
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Insulin Resistance in Hepatocytes
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Proteins Involved in non-Alcoholic Fatty Liver Disease
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beta-Cell Mass Regulation
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beta-Cell Function Inhibition by Rapamycin (Rodent Model)
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Cardiovascular Effects in Hyperthyroidism
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Thyroid Dysfunction
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Proteins Involved in Obesity
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Proteins Involved in Colorectal Neoplasms
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Cetuximab Resistance in Colorectal Cancer
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Peutz-Jeghers Syndrome
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Acute Myeloid Leukemia
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B-Cell Acute Lymphoblastic Leukemia
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B-Cell Chronic Lymphocytic Leukemia
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Chronic Myeloid Leukemia
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Proteins Involved in Chronic Myeloid Leukemia
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Diffuse Large-B-Cell Lymphoma
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Diffuse Large-B-Cell Lymphoma ABC Subtype
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Lymphoma, GCB Subtype
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Follicular Lymphoma
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Hodgkin Lymphoma
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Mantle Cell Lymphoma
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mTOR/NF-kB/BCR Signaling Disregulation in Mantle Cell Lymphoma
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Osteoclast Activation in Multiple Myeloma
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IL6/IGF1/VEGFA Signaling in Multiple Myeloma
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Multiple Myeloma
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Proteins Involved in T-Cell Acute Lymphoblastic Leukemia
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T-Cell Acute Lymphoblastic Leukemia
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Proteins Involved in Hepatocellular Carcinoma
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Hepatocellular Carcinoma
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Growth Factor Signaling in Hepatocellular Carcinoma
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Pancreatic Ductal Carcinoma
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Growth Factor Signaling in Pancreatic Neoplasms
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Pancreatic Neuroendocrine Tumors
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TNF Receptor Associated Periodic Syndrome
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Cowden Syndrome
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Huntingtin Mutant Protein Toxicity Effects
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Proteins Involved in Huntington Disease
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Proteins Involved in Autistic Disorder and Aggression
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IL6 and Insulin Resistance in Muscular Dystrophies
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IL6 Promotes Inflammation in Muscular Dystrophies
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Muscular Dystrophies
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Dystrophin Glycoprotein Complex Signaling in Muscular Dystrophies
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Proteins Involved in Alzheimer's Disease
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Proteins Involved in Epilepsy
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Ketogenic Diet Mechanism (Hypothesis)
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Blood-Brain Barrier Disruption in Epileptiform Disorders
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mTOR Hyperactivation after Status Epilepticus
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Glioblastoma, Primary
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Proteins Involved in Glioblastoma
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Glioblastoma, Secondary
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Astrocytoma
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Proteins Involved in Glioma
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Neuroblastoma
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ALK Associated Neuroblastoma
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Sonic Hedgehog Signaling in Neuroblastoma
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Proteins Involved in Neuroblastoma
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Proteins Involved in Breast Cancer Related to ESR1 Signaling Pathway
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Proteins Involved in Breast Cancer Related to ERBB2/VEGFR/Akt Signaling Pathway
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ERBB/VEGFR/Akt Signaling in Breast Cancer
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IGF1R/AKT Signaling in Breast Cancer
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ESR1/ERBB Positive Luminal Breast Cancer
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Proteins Involved in Breast Cancer Related to IGF1R/Akt Signaling Pathway
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Breast Cancer
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ESR1 Signaling in Breast Cancer
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Endometrial Cancer
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Endometrioid Endometrial Cancer
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Clear Cell Endometrial Cancer and Papillary Serous Endometrial Cancer
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Proteins Involved in Endometriosis
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Angiogenesis in Endometriosis
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Genes with Mutations Associated with Hereditary Breast and/or Ovarian Cancer Syndrome
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Proteins Involved in High-Grade Serous Ovarian Carcinoma
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Endometrioid Ovarian Carcinoma
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Proteins Involved in Endometrioid Ovarian Carcinoma
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Clear Cell Ovarian Carcinoma
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Proteins Involved in Mucinous Ovarian Carcinoma
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High-Grade Serous Ovarian Carcinoma
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Low-Grade Serous Ovarian Carcinoma
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Proteins Involved in Low-Grade Serous Ovarian Carcinoma
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Ovarian Cancer
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Proteins Involved in Clear Cell Ovarian Carcinoma
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Mucinous Ovarian Carcinoma
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Proteins with Altered Expression in Ovarian Cancer
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Proteins Involved in Primary Ovarian Insufficiency
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HPV E5 Regulates EDNRA and EGFR Signaling Pathway in Keratinocytes
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Androgen Receptor/Akt Signaling
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Androgen Receptor and Cell Cycle in Prostate Cancer
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Proteins Involved in Prostate Cancer
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Androgen Receptor/SGK1 Signaling
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Polycystins Mutation Effects in Cystic Kidney Disease
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Proteins Involved in Polycystic Kidney Disease
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AREG -> HIF1A Expression Targets
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Noradrenaline/Gs Expression Targets
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Epinephrine/Gs Expression Targets
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EGF -> HIF1A Expression Targets
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EGFR/ERBB2 -> HIF1A Signaling
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EREG -> HIF1A Expression Target
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HBEGF -> HIF1A Expression Targets
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TAM Receptor Signaling Activation in Cancer
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PI3K/AKT/MTOR Signaling Activation in Cancer
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N2 Neutrophils in Tumor-Promoting Inflammation and Tumor Progression
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TGFB Signaling activation by Blocking of Tumor Suppressors
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PI3K/AKT/MTOR Signaling Activation by Blocking of Tumor Suppressors
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FBLN5 Potentiates Migration and Proliferation of Endothelial Cells in Cancer
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HIF1A as Master Regulator of Angiogenesis in Cancer
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VEGF Independent Angiogenesis in Cancer
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MTOR/TORC in Cancer Cell Motility and Invasion
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TGFB Family in Epithelial to Mesenchymal Transition in Cancer
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Respiratory Chain Impairment in Cancer
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Skeletal Muscle Wasting in Cancer Cachexia
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Glutamine in Cancer Metabolism
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Mutations in Krebs Cycle Enzymes in Cancer
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IDO1 in Cancer Immune Escape
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ICAM2 -> CTNNB/FOXO/STAT3 Signaling
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NRG1 -> HIF1A Expression Target
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Lysophosphatidic Acid/LPARs Signaling
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Androgen Receptor non-Genomic Signaling
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MERTK Signaling
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TGF-beta Signaling
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AMPK Signaling
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AXL Receptor Tyrosine Kinase Signaling
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mTOR Signaling
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VEGF Signaling
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EGFR Signaling
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TGFA -> HIF1A Expression Targets
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ROS in Angiotensin Mediated Cardiovascular Remodeling and Hypertrophy
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ace2
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PPAR Psoriasis
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Model of PPARG signaling in psoriasis
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Model of PPARG related pathways in psoriasis (short version)
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2_Interleukin-17 and interleukin-22 signaling in psoriasis
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1_Formation of cysts in polycystic kidney disease
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3_Enhanced angiogenesis in endometriosis
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2_Cardiomyocyte hypertrophy
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2_Neuron and Schwann cell death
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drug-target pairs direct regulation
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Interleukin-17 and interleukin-22 signaling in psoriasis
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