URN | urn:agi-llid:5609 |
---|---|
Total Entities | 0 |
Connectivity | 846 |
Name | MAP2K7 |
Description | mitogen-activated protein kinase kinase 7 |
Notes | The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically activates MAPK8/JNK1 and MAPK9/JNK2, and this kinase itself is phosphorylated and activated by MAP kinase kinase kinases including MAP3K1/MEKK1, MAP3K2/MEKK2,MAP3K3/MEKK5, and MAP4K2/GCK. This kinase is involved in the signal transduction mediating the cell responses to proinflammatory cytokines, and environmental stresses. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014] |
Primary Cell Localization | Cytoplasm |
Class | Protein kinase |
Pathway | Osteoarthritis |
---|---|
Skin Aging | |
Thrombopoietin Receptors Signaling in Platelet Maturation | |
Toll-like Receptors Act through MYD88-TIRAP Signaling | |
TLR4 Signaling in Leukocytes | |
T-Cell Dependent B-Cell Activation | |
T-Cell Independent B-Cell Activation | |
Peripheral T-Cell Tolerance | |
Th1-Cell Differentiation | |
Treg-Cell Differentiation | |
Th2-Cell Differentiation | |
T-Cell Receptor Signaling | |
Plasmin Effects in Inflammation | |
MC1R in anti-Inflammatory Signaling | |
Basophil Activation | |
Mast-Cell Activation via IgE Signaling | |
Mast-Cells De Novo Synthesized Mediators via IgE Independent Signaling | |
Neutrophil Recruitment and Priming | |
Nociception Expression Targets Signaling | |
ADRA1A -> IL6 Production | |
CNR1/2 -> IL1B/2/4/6/10 Production | |
DRD2 Expression Targets | |
PTGER2/3 -> Inflammation-Related Expression Targets | |
Circadian Clock Genes in Suprachiasmatic Nuclei Neurons | |
Apoptosis | |
Th1-Cells Activation and Proliferation in Atherosclerosis | |
Inflammatory Reaction in Acne Vulgaris | |
Atopic Dermatitis Onset | |
Mast-Cells Activation in Atopic Dermatitis | |
IL17 Signaling in Psoriasis | |
Th0-Cell Aberrant Activation in Systemic Lupus Erythematosus | |
B-Cell Activation in Systemic Lupus Erythematosus | |
Th2-Cell Function in Systemic Lupus Erythematosus | |
Acute Cytotoxic CD8+T-Cell Response against Melanocytes | |
Vitiligo | |
T-Cell Cytotoxic Response against Melanocytes in Vitiligo | |
Apoptosis of Melanocyte in Vitiligo | |
Humoral Immunity in Vitiligo | |
Treg-Cell Function in Diabetes Mellitus Type 1 | |
Natural Killer T-Cell Roles in Diabetes Mellitus Type 1 | |
non-Suppressive Treg-Cell in Diabetes Mellitus Type 1 | |
TLR2 Signaling in Treg-Cell in Type 1 Diabetes (Animal Model) | |
Treg-Cell Activation in Diabetes Mellitus | |
beta-Cell Destruction through Cytokines in Diabetes Mellitus | |
Apoptosis of Thyroid Cell in Hashimoto's Thyroiditis | |
GNRH Signaling Impairment in Hypogonadotrophic Hypogonadism | |
CD4+T-Cell Response in Celiac Disease | |
OipA Signaling in Helicobacter Pylori Infection | |
Th2-Cell Function in Ulcerative Colitis | |
T-Cell Cytotoxic Response in Ulcerative Colitis | |
Osteoclast Activation in Multiple Myeloma | |
SERPINA1 Associated Liver Damage | |
Pancreatic Ductal Carcinoma | |
Pancreatic Neuroendocrine Tumors | |
TGFBR Signaling in Pancreatic Neoplasms | |
IgE Induces Airway Smooth Muscle Cell Proliferation | |
Basophil Activation in Asthma | |
Mast-Cell Activation in Asthma | |
Th2-Cell Response in Asthma | |
Mucin Production in Goblet Airway Epithelial Cells | |
Osteoclast Activation in Gout | |
TNF and IL1B Induce Metalloproteinase Synthesis in Osteoarthritis | |
Apoptosis of Chondrocyte | |
Dendritic Cell Dysfunction in Psoriatic Arthritis | |
Synovial Fibroblast Activation in Psoriatic Arthritis | |
Keratinocyte Activation in Psoriatic Arthritis | |
PTPN22 Role in Rheumatoid Arthritis | |
Osteoclast Activation in Rheumatoid Arthritis | |
Synovial Fibroblast Activation by Citokines in Rheumatoid Arthritis | |
Apoptosis Block in Synovial Fibroblast | |
FAS Mediated Apoptosis in Systemic Scleroderma | |
B-Cells Function in Systemic Scleroderma | |
Th2-Cells Function in Systemic Scleroderma | |
Skin Fibrosis | |
CCR5 Signaling in Macrophages | |
CD4+ T-Cell Function Decline in HIV | |
Apoptosis Block in Infected Cells | |
CD4+ T-Cell Death in HIV | |
TNF Receptor Associated Periodic Syndrome | |
ER Stress in Huntington Disease | |
Osteoclast Activation in Postmenopause | |
Glioma Invasion Signaling | |
Growth Factor Signaling in Neuroblastoma | |
Neuroblastoma | |
WNT Signaling in Breast Cancer | |
Angiogenesis in Endometriosis | |
Subepithelial Fibroblasts in Middle Ear Cholesteatoma | |
HPV E5 Regulates EDNRA and EGFR Signaling Pathway in Keratinocytes | |
ER Stress in Macular Degeneration | |
MYOC Associated Glaucoma | |
Immune System Role in Otitis Media | |
Alveolar Macrophage Negative Regulation Declined in COPD | |
Alveolar Macrophages Dysfunction in COPD | |
T-Cell Cytotoxic Activation | |
Mucin Hyperproduction in Goblet and Mucous Cells | |
WNT Signaling in Cystic Kidney Disease | |
Plasmin Role in Glomerulonephritis | |
Podocyte Dysfunction in Glomerulonephritis | |
CD38/CD19 -> JUN/FOS/NF-kB Signaling in B-cell Proliferation | |
ANGPT2 -> AP-1/CREBBP/MYC Expression Targets | |
AREG -> AP-1 Expression Targets | |
Dopamine/Gi Expression Targets | |
BTC -> AP-1/ATF/CREB Expression Targets | |
Frizzled Receptors -> ARRB1/ARRB2 non-Canonical Signaling | |
Complement Component GPCRs Signaling | |
EGF -> AP-1/ATF Expression Targets | |
EGF -> CREB/CREBBP/ELK/SRF/MYC Expression Targets | |
EGF -> TP53 Expression Targets | |
EGFR/ERBB2 -> TP53 Signaling | |
EGFR -> AP-1/ATF2 Signaling | |
EGFR -> AP-1/CREB/ELK/SRF/MYC Signaling | |
EREG -> AP-1/ATF Expression Targets | |
Erythropoietin -> AP-1/MYC/CREB Expression Targets | |
F2 -> AP-1/CREB/ELK/SRF/SP1 Expression Targets | |
PLG -> AP-1/CREB/ELK/SRF/SP1 Expression Targets | |
FGF9 -> AP-1/CREB/MYC Expression Targets | |
FGF10 -> AP-1/CREB/CREBBP/MYC Expression Targets | |
FGF1 -> AP-1/CREB/ELK/SRF/MYC Expression Targets | |
FGF8 -> AP-1/CREB/MYC Expression Targets | |
FGF18 -> AP-1/CREB Expression Targets | |
FGF4 -> AP-1/MYC Expression Targets | |
FGF7 -> AP-1/CREB/CREBBP/MYC Expression Targets | |
FGF2 -> AP-1/CREB/CREBBP/ELK/SRF/MYC Expression Targets | |
FGFR -> AP-1/CREB/CREBBP/ELK/SRF/MYC Signaling | |
FrizzledR -> JUN/PAX2 Signaling | |
HBEGF -> AP-1/ATF Expression Targets | |
HBEGF -> TP53 Expression Targets | |
HBEGF -> CREB/MYC Expression Targets | |
HGF -> AP-1/CREB/ELK/SRF/MYC Expression Targets | |
HGFR -> AP-1/CREB/MYC Signaling | |
RAS/RAF/MAPK Signaling Activation in Cancer | |
RAS/RAF/MAPK Signaling Activation by Blocking of Tumor Suppressors | |
Apoptosis Block by Death Receptor Signaling in Cancer | |
Apoptosis Evasion in Cancer: Overview | |
VEGFA Dependent Angiogenesis in Cancer | |
VEGF Independent Angiogenesis in Cancer | |
Effector T-cell Inactivation in Cancer Immune Escape | |
FibronectinR -> AP-1/ELK/SRF/SREBF Signaling | |
CTGF -> AP-1/CREB/MYC Expression Targets | |
PAF/Gq -> AP-1/ATF1/CREB/ERK/SRF Expression Targets | |
Dronabinol/Anandamide Expression Targets | |
S1P Expression Targets | |
NRG1 -> CREB/CREBBP/ELK/SRF/MYC Expression Targets | |
NRG1 -> TP53 Expression Target | |
NRG1 -> AP-1/ATF Expression Targets | |
NGF -> SMAD3/NF-kB Expression Targets | |
NGF -> AP-1/TP53/MYC Expression Targets | |
BDNF Expression Targets | |
NTF3 Expression Targets | |
NTF4 Expression Targets | |
NOTCH -> TCF3 Signaling | |
NOTCH Expression Targets | |
PDGFB -> AP-1/CREB/MYC Expression Target | |
PDGFD -> AP-1 Expression Targets | |
PDGF -> AP-1/CREB/CREBBP/MYC Expression Targets | |
PDGFR -> AP-1/MYC Signaling | |
AVP/Gs -> CREB/ELK/SRF/AP-1/EGR Expression Targets | |
GNRH1 Expression Targets | |
GNRH2 Expression Targets | |
EDN1 Expression Targets | |
EDN3 Expression Targets | |
AVP/Gq -> CREB/ELK/SRF/AP-1/EGR Expression Targets | |
AngiopoietinR -> AP-1 Signaling | |
GDNF -> HSF1 Signaling | |
EphrinB -> MAPK/JUN/FOS Signaling | |
NTRK -> AP-1/CREB/ELK/SRF/MYC/SMAD3/TP53 Signaling | |
GAS6 -> AP-1/CREB Expression Targets | |
FIGF -> AP-1 Expression Target | |
KITLG -> AP-1/CREB/CREBBP/MYC Expression Targets | |
GDNF -> HSF1 Expression Targets | |
CSF1 -> AP-1/CREB/CREBBP/MYC Expression Targets | |
PGF -> AP-1/CREB/CREBBP/MYC Expression Targets | |
FLT3LG -> AP-1/CREB/CREBBP Expression Targets | |
TNF-alpha/TNFRSF1A Signaling | |
JNK/MAPK Signaling | |
VEGF Signaling | |
EGFR Signaling | |
WNT Planar Cell Polarity (PCP) non-Canonical Signaling | |
T-Cell Receptor -> AP-1 Signaling | |
TGFA -> TP53 Expression Targets | |
TGFA/AP-1/ATF Expression Targets | |
TGFA -> CREB/CREBBP/ELK-SRF/MYC Expression Targets | |
FASLG Expression Targets | |
TNFSF10 Expression Targets | |
LTA Expression Targets | |
TNFSF14 Expression Targets | |
TNF -> AP-1 Expression Targets | |
CD72 -> AP-1 Expression Targets | |
CD40LG -> NF-kB/ELK/SRF -> CREB/NFATC Expression Targets | |
TNFSF13 Expression Targets | |
TNFSF13B Expression Targets | |
TNF -> ELK-SRF Expression Targets | |
TNF -> TP53/ATF Expression Targets | |
EDA Expression Targets | |
EctodysplasinR -> AP-1 Signaling | |
TNFR -> CREB/ELK-SRF Signaling | |
TNFR -> AP-1/ATF/TP53 Signaling | |
NGFR -> AP-1/CEBPB/CREB/ELK/SRF/TP53 Signaling | |
TNFRSF6 -> DDIT3 Signaling | |
TNFRSF6 -> HSF1 Signaling | |
TNFRSF1A -> AP-1/ATF/TP53 Signaling | |
TNFRSF1A -> CREB/ELK-SRF Signaling | |
Thrombopoietin -> SPI1 Expression Targets | |
Thrombopoietin -> AP-1/CREB/CREBBP/MYC Expression Targets | |
IL1B -> PGE2 Expression Targets | |
ROS in Angiotensin Mediated Cardiovascular Remodeling and Hypertrophy | |
VEGFA -> AP-1/CREBBP/MYC Expression Targets | |
VEGFR -> AP-1/CREB/MYC Signaling | |
WNT1 Expression Targets | |
WNT3A Expression Targets | |
WNT4 Expression Targets | |
WNT5A Expression Targets | |
WNT7A Expression Targets | |
1_Inflammation in keratinocytes in the pathology of acne | |
2_Acute phase initiation in atopic dermatitis | |
2_Interleukin-17 and interleukin-22 signaling in psoriasis | |
1_The onset of atopic dermatitis | |
1_TNF and IL1B provoke ECM degradation in osteoarthritis | |
1_Osteoclast-mediated bone resorption in postmenopausal women | |
2_Chondrocyte death in osteoarthritis | |
1_Formation of cysts in polycystic kidney disease | |
3_Mesangial cell dysfunction in glomerulonephritis | |
2_Podocyte dysfunction in glomerulonephritis | |
1_Disruption of luteinizing hormone and follicle-stimulating hormone secretion in PCOS | |
2_MYOC-associated glaucoma | |
3_Endoplasmic reticulum stress in age-related macular degeneration | |
2_Cigarette smoke and inflammation cause alveolar epithelial cell death in COPD | |
3_Role of alveolar macrophages in pulmonary tissue destruction in COPD | |
2_Lipotoxicity in NAFLD | |
2_HIV - induced depletion of CD4+ T-cells | |
4_3_Insulin resistance: FFA-related insulin resistance | |
2_SERPINA1-associated liver damage | |
mapk1 protein modificators | |
Interleukin-17 and interleukin-22 signaling in psoriasis |
MedScan ID | 5609 |
---|
LocusLink ID | 5609 |
---|---|
26400 | |
363855 |
Alias | JNKK2 |
---|---|
MAPK kinase 7 | |
Dual specificity mitogen-activated protein kinase kinase 7 | |
5930412N11 | |
c-Jun N-terminal kinase kinase II | |
JNK kinase 2 | |
stress-activated protein kinase kinase-4 SKK4 | |
ERK kinase VII | |
MAP kinase kinase VII | |
MAPK/ERK kinase VII | |
Map2k7 | |
JNK kinase II | |
mitogen-activated protein kinase kinase VII | |
OTTMUSP00000045502 | |
OTTMUSP00000017733 | |
MEK 7 | |
OTTMUSP00000022436 | |
OTTMUSP00000017734 | |
protein kinase, mitogen-activated, kinase VII | |
stress-activated protein kinase kinase 4 | |
c-Jun N-terminal kinase kinase 2 | |
MAP kinase kinase 7 | |
PRKMK7 | |
MAPK/ERK kinase 7 | |
MKK7/JNKK2/SKK4 | |
MKK7 | |
LOC199677 | |
mitogen activated protein kinase kinase 7 | |
SAPKK4 | |
protein kinase, mitogen activated, kinase 7 | |
MAPK kinase VII | |
JNK activating kinase II | |
Dual specificity mitogen-activated protein kinase kinase VII | |
5930412N11Rik | |
OTTMUSP00000017732 | |
OTTMUSP00000022434 | |
OTTHUMP00000174397 | |
JNK activating kinase 2 | |
ERK kinase 7 | |
Sek2 | |
SKK4/MKK7 | |
MKK7a | |
OTTMUSP00000022437 | |
MAPKK7 | |
OTTMUSP00000022435 | |
SAPK kinase 4 | |
MEK | |
SAPKK-4 | |
JNK-activating kinase 2 | |
Mek7 | |
JNKK 2 | |
MAPKK 7 | |
JNKK | |
SKK4 | |
2 | |
map2k7 {ECO:0000312|EMBL:AAX61178.1} | |
mitogen-activated protein kinase kinase 7 | |
JNK activating kinase 2 | |
JNK kinase II | |
JNK activating kinase II | |
JNK kinase 2 | |
protein kinase, mitogen-activated, kinase 7 | |
MAPKK7s | |
PRKMK7s |
EC Number | 2.7.12.2 |
---|
GO ID | 0005524 |
---|---|
0008545 | |
0004708 | |
0019899 | |
0000287 | |
0019901 | |
0019903 | |
0004674 | |
0004713 | |
0038095 | |
0007254 | |
0007257 | |
0000187 | |
0032147 | |
0006915 | |
0018108 | |
0070374 | |
0051973 | |
1904355 | |
0032212 | |
0045893 | |
0009411 | |
0009408 | |
0006970 | |
0034612 | |
0007165 | |
0023014 | |
0051403 | |
0031098 | |
0005737 | |
0005829 | |
0005634 | |
0031435 | |
0008022 | |
0043525 | |
0001934 | |
0006468 | |
2000671 | |
0009611 | |
0072709 | |
0004702 | |
0035897 | |
0016301 | |
0046872 | |
0000166 | |
0004672 | |
0016740 | |
0016310 | |
0006950 | |
0007346 | |
0005622 | |
0002755 | |
0002756 | |
0035666 | |
0045087 | |
0009405 | |
0034166 | |
0034134 | |
0034138 | |
0034142 | |
0034146 | |
0034162 | |
0038123 | |
0038124 | |
0002224 | |
0016772 | |
0008063 | |
0034130 | |
0005515 |
KEGG ID | hsa:5609 |
---|---|
mmu:26400 | |
rno:363855 |
CellType | cells in endometrial stroma |
---|---|
glandular cells | |
trophoblastic cells | |
germinal center cells | |
squamous epithelial cells | |
cells in seminiferus ducts | |
non-germinal center cells | |
glial cells | |
epidermal cells | |
Leydig Cells | |
respiratory epithelial cells | |
neuronal cells | |
cells in glomeruli | |
myocytes | |
follicle cells | |
cells in tubules | |
ovarian stroma cells | |
lymphoid tissue | |
exocrine glandular cells | |
hematopoietic cells | |
urothelial cells | |
smooth muscle cells | |
islets of Langerhans | |
bile duct cells | |
cells in red pulp | |
Hepatocytes | |
decidual cells | |
Macrophages | |
cells in granular layer | |
Pneumocytes | |
cells in molecular layer | |
Purkinje Cells | |
cells in white pulp |
Tissue | uterus, pre-menopause |
---|---|
stomach, lower | |
Placenta | |
stomach, upper | |
Prostate | |
lymph node | |
vagina | |
testis | |
rectum | |
hippocampus | |
vulva/anal skin | |
Salivary gland | |
nasopharynx | |
cerebral cortex | |
thyroid gland | |
seminal vesicle | |
oral mucosa | |
Kidney | |
cervix, uterine | |
Adrenal gland | |
tonsil | |
skeletal muscle | |
Ovary | |
Appendix | |
Skin | |
lateral ventricle | |
colon | |
small intestine | |
Pancreas | |
duodenum | |
bone marrow | |
urinary bladder | |
smooth muscle | |
Liver | |
epididymis | |
breast | |
spleen | |
parathyroid gland | |
esophagus | |
bronchus | |
Lung | |
fallopian tube | |
Cerebellum | |
gall bladder | |
heart muscle | |
uterus, post-menopause |
Organism | Homo sapiens {Organism urn:agi-taxid:9606} |
---|---|
Mus musculus {Organism urn:agi-taxid:10090} | |
Rattus norvegicus {Organism urn:agi-taxid:10116} | |
Homo sapiens | |
Mus musculus | |
Rattus norvegicus |
Mouse chromosome position | 8 |
---|---|
8 A1.1 |
OMIM ID | 603014 |
---|
Rat chromosome position | 12p12 |
---|
Hugo ID | 6847 |
---|---|
HGNC:6847 |
Human chromosome position | 19p13.2 |
---|---|
19p13.3-p13.2 |
Swiss-Prot ID | MP2K7_HUMAN |
---|---|
MP2K7_MOUSE | |
MP2K7_RAT | |
B2R9S5_HUMAN |
Cell Localization | Nucleus |
---|---|
Cytoplasm |
Ensembl ID | ENSG00000076984 |
---|---|
ENSP00000381070.2 | |
ENST00000397983.7 | |
ENSP00000381068.3 | |
ENST00000397981.7 | |
ENSP00000381066.3 | |
ENST00000397979.3 | |
ENSMUSG00000002948 | |
ENSMUSP00000003027.7 | |
ENSMUST00000003027.13 | |
ENSMUSP00000054512.4 | |
ENSMUST00000062686.10 | |
ENSMUSP00000106627.1 | |
ENSMUST00000110999.7 | |
ENSMUSP00000106623.1 | |
ENSMUST00000110995.7 | |
ENSMUSP00000106622.1 | |
ENSMUST00000110994.8 | |
ENSMUSP00000106626.2 | |
ENSMUST00000110998.8 | |
ENSRNOG00000001047 | |
ENSRNOP00000058535.3 | |
ENSRNOT00000061821.3 | |
ENSRNOP00000072160.1 | |
ENSRNOT00000084460.1 | |
ENSP00000381070 | |
ENST00000397983 | |
ENSP00000381068 | |
ENST00000397981 | |
ENSP00000381066 | |
ENST00000397979 | |
ENSMUSG00000109061 | |
ENSMUSP00000003027 | |
ENSMUST00000003027 | |
ENSMUSP00000054512 | |
ENSMUST00000062686 | |
ENSMUSP00000106627 | |
ENSMUST00000110999 | |
ENSMUSP00000106623 | |
ENSMUST00000110995 | |
ENSMUSP00000106622 | |
ENSMUST00000110994 | |
ENSMUSP00000106626 | |
ENSMUST00000110998 | |
ENSRNOP00000058535 | |
ENSRNOT00000061821 | |
ENSRNOP00000072160 | |
ENSRNOT00000084460 |
MGI ID | MGI:1346871 |
---|---|
1346871 |
RGD ID | 1560043 |
---|
Unigene ID | Hs.531754 |
---|---|
Mm.3906 | |
Rn.162081 |
Homologene ID | 56548 |
---|
Shape | Sickle-vertex |
---|
IPI ID | IPI00023636 |
---|---|
IPI00302112 | |
IPI00745806 | |
IPI00794495 | |
IPI00779757 | |
IPI00117840 | |
IPI00228989 | |
IPI00280475 | |
IPI00749972 | |
IPI00816840 | |
IPI00816864 | |
IPI00816890 | |
IPI00816911 | |
IPI00747921 | |
IPI00641984 | |
IPI00639798 | |
IPI00189128 |
Ensembl Transcript ID | ENST00000397979 |
---|
ENSEMBL | ENSG00000076984 |
---|
ProteinAtlas SubcellularLocation | Main location: ; Other location: ; Expression type: Staining; Reliability: Uncertain |
---|
Ensembl Gene ID | ENSG00000076984 |
---|
ProteinAtlas NormalTissue | Tissue: vulva/anal skin; Cell type: epidermal cells; Level: Moderate; Expression type: Staining; Reliability: Supportive |
---|---|
Tissue: pancreas; Cell type: islets of Langerhans; Level: Weak; Expression type: Staining; Reliability: Supportive | |
Tissue: pancreas; Cell type: exocrine glandular cells; Level: Moderate; Expression type: Staining; Reliability: Supportive | |
Tissue: spleen; Cell type: cells in red pulp; Level: Weak; Expression type: Staining; Reliability: Supportive | |
Tissue: smooth muscle; Cell type: smooth muscle cells; Level: Weak; Expression type: Staining; Reliability: Supportive | |
Tissue: adrenal gland; Cell type: glandular cells; Level: Low; Expression type: APE; Reliability: High | |
Tissue: appendix; Cell type: glandular cells; Level: Medium; Expression type: APE; Reliability: High | |
Tissue: appendix; Cell type: lymphoid tissue; Level: Medium; Expression type: APE; Reliability: High | |
Tissue: bone marrow; Cell type: hematopoietic cells; Level: High; Expression type: APE; Reliability: High | |
Tissue: breast; Cell type: glandular cells; Level: Medium; Expression type: APE; Reliability: High | |
Tissue: bronchus; Cell type: respiratory epithelial cells; Level: Medium; Expression type: APE; Reliability: High | |
Tissue: cerebellum; Cell type: cells in granular layer; Level: Low; Expression type: APE; Reliability: High | |
Tissue: cerebellum; Cell type: cells in molecular layer; Level: Low; Expression type: APE; Reliability: High | |
Tissue: cerebellum; Cell type: Purkinje cells; Level: Low; Expression type: APE; Reliability: High | |
Tissue: cerebral cortex; Cell type: glial cells; Level: Medium; Expression type: APE; Reliability: High | |
Tissue: cerebral cortex; Cell type: neuronal cells; Level: Medium; Expression type: APE; Reliability: High | |
Tissue: cervix, uterine; Cell type: glandular cells; Level: Medium; Expression type: APE; Reliability: High | |
Tissue: cervix, uterine; Cell type: squamous epithelial cells; Level: Low; Expression type: APE; Reliability: High | |
Tissue: colon; Cell type: glandular cells; Level: Medium; Expression type: APE; Reliability: High | |
Tissue: duodenum; Cell type: glandular cells; Level: Medium; Expression type: APE; Reliability: High | |
Tissue: epididymis; Cell type: glandular cells; Level: Low; Expression type: APE; Reliability: High | |
Tissue: esophagus; Cell type: squamous epithelial cells; Level: Medium; Expression type: APE; Reliability: High | |
Tissue: fallopian tube; Cell type: glandular cells; Level: Medium; Expression type: APE; Reliability: High | |
Tissue: gall bladder; Cell type: glandular cells; Level: Medium; Expression type: APE; Reliability: High | |
Tissue: heart muscle; Cell type: myocytes; Level: None; Expression type: APE; Reliability: High | |
Tissue: hippocampus; Cell type: glial cells; Level: Low; Expression type: APE; Reliability: High | |
Tissue: hippocampus; Cell type: neuronal cells; Level: Low; Expression type: APE; Reliability: High | |
Tissue: kidney; Cell type: cells in glomeruli; Level: Medium; Expression type: APE; Reliability: High | |
Tissue: kidney; Cell type: cells in tubules; Level: Medium; Expression type: APE; Reliability: High | |
Tissue: lateral ventricle; Cell type: glial cells; Level: Low; Expression type: APE; Reliability: High | |
Tissue: lateral ventricle; Cell type: neuronal cells; Level: Low; Expression type: APE; Reliability: High | |
Tissue: liver; Cell type: bile duct cells; Level: Low; Expression type: APE; Reliability: High | |
Tissue: liver; Cell type: hepatocytes; Level: Low; Expression type: APE; Reliability: High | |
Tissue: lung; Cell type: macrophages; Level: Medium; Expression type: APE; Reliability: High | |
Tissue: lung; Cell type: pneumocytes; Level: None; Expression type: APE; Reliability: High | |
Tissue: lymph node; Cell type: germinal center cells; Level: Medium; Expression type: APE; Reliability: High | |
Tissue: lymph node; Cell type: non-germinal center cells; Level: Medium; Expression type: APE; Reliability: High | |
Tissue: nasopharynx; Cell type: respiratory epithelial cells; Level: Medium; Expression type: APE; Reliability: High | |
Tissue: oral mucosa; Cell type: squamous epithelial cells; Level: Low; Expression type: APE; Reliability: High | |
Tissue: ovary; Cell type: follicle cells; Level: Low; Expression type: APE; Reliability: High | |
Tissue: ovary; Cell type: ovarian stroma cells; Level: Low; Expression type: APE; Reliability: High | |
Tissue: pancreas; Cell type: exocrine glandular cells; Level: Medium; Expression type: APE; Reliability: High | |
Tissue: pancreas; Cell type: islets of Langerhans; Level: Low; Expression type: APE; Reliability: High | |
Tissue: parathyroid gland; Cell type: glandular cells; Level: Medium; Expression type: APE; Reliability: High | |
Tissue: placenta; Cell type: decidual cells; Level: Low; Expression type: APE; Reliability: High | |
Tissue: placenta; Cell type: trophoblastic cells; Level: Medium; Expression type: APE; Reliability: High | |
Tissue: prostate; Cell type: glandular cells; Level: Medium; Expression type: APE; Reliability: High | |
Tissue: rectum; Cell type: glandular cells; Level: Medium; Expression type: APE; Reliability: High | |
Tissue: salivary gland; Cell type: glandular cells; Level: Low; Expression type: APE; Reliability: High | |
Tissue: seminal vesicle; Cell type: glandular cells; Level: Medium; Expression type: APE; Reliability: High | |
Tissue: skeletal muscle; Cell type: myocytes; Level: None; Expression type: APE; Reliability: High | |
Tissue: skin; Cell type: epidermal cells; Level: Low; Expression type: APE; Reliability: High | |
Tissue: small intestine; Cell type: glandular cells; Level: Medium; Expression type: APE; Reliability: High | |
Tissue: smooth muscle; Cell type: smooth muscle cells; Level: Low; Expression type: APE; Reliability: High | |
Tissue: spleen; Cell type: cells in red pulp; Level: Low; Expression type: APE; Reliability: High | |
Tissue: spleen; Cell type: cells in white pulp; Level: Low; Expression type: APE; Reliability: High | |
Tissue: stomach, lower; Cell type: glandular cells; Level: Medium; Expression type: APE; Reliability: High | |
Tissue: stomach, upper; Cell type: glandular cells; Level: Medium; Expression type: APE; Reliability: High | |
Tissue: testis; Cell type: cells in seminiferus ducts; Level: High; Expression type: APE; Reliability: High | |
Tissue: testis; Cell type: Leydig cells; Level: Low; Expression type: APE; Reliability: High | |
Tissue: thyroid gland; Cell type: glandular cells; Level: Low; Expression type: APE; Reliability: High | |
Tissue: tonsil; Cell type: germinal center cells; Level: Medium; Expression type: APE; Reliability: High | |
Tissue: tonsil; Cell type: non-germinal center cells; Level: Medium; Expression type: APE; Reliability: High | |
Tissue: tonsil; Cell type: squamous epithelial cells; Level: Low; Expression type: APE; Reliability: High | |
Tissue: urinary bladder; Cell type: urothelial cells; Level: Medium; Expression type: APE; Reliability: High | |
Tissue: uterus, post-menopause; Cell type: cells in endometrial stroma; Level: None; Expression type: APE; Reliability: High | |
Tissue: uterus, post-menopause; Cell type: glandular cells; Level: Low; Expression type: APE; Reliability: High | |
Tissue: uterus, pre-menopause; Cell type: cells in endometrial stroma; Level: Low; Expression type: APE; Reliability: High | |
Tissue: uterus, pre-menopause; Cell type: glandular cells; Level: Medium; Expression type: APE; Reliability: High | |
Tissue: vagina; Cell type: squamous epithelial cells; Level: Medium; Expression type: APE; Reliability: High | |
Tissue: vulva/anal skin; Cell type: epidermal cells; Level: Medium; Expression type: APE; Reliability: High |