Protein KRT10

URN urn:agi-llid:3858
Total Entities 0
Connectivity 737
Name KRT10
Description keratin 10
Notes This gene encodes a member of the type I (acidic) cytokeratin family, which belongs to the superfamily of intermediate filament (IF) proteins. Keratins are heteropolymeric structural proteins which form the intermediate filament. These filaments, along with actin microfilaments and microtubules, compose the cytoskeleton of epithelial cells. Mutations in this gene are associated with epidermolytic hyperkeratosis. This gene is located within a cluster of keratin family members on chromosome 17q21. [provided by RefSeq, Jul 2008]
Primary Cell Localization Cytoplasm

Pathway Proteins Involved in Ichthyosis
Ichthyosis Vulgaris
Genes with Mutations Associated with Ichthyosis
IL22 Induces Keratinocyte Proliferation in Psoriasis
Proteins with Altered Expression in Psoriasis
EGFR -> Expression Targets in Skin
Elevated Receptors -> Expression Targets in Skin
NOTCH -> Expression Targets in Skin
2_Interleukin-17 and interleukin-22 signaling in psoriasis
1_Ichthyosis vulgaris overview
Interleukin-17 and interleukin-22 signaling in psoriasis

MedScan ID 3858

LocusLink ID 3858

Alias Keratin-10
D130054E02
KA10
keratin 10, type I
Keratin X
epidermal keratin 10
OTTMUSP00000005149
Keratin, type I cytoskeletal 10
KRT10
keratin 10 (epidermolytic hyperkeratosis, keratosis palmaris et plantaris)
K1C I
type I keratin KA10
cytokeratin 10
CG15306-PA
56 kDa cytokeratin
suprabasal cytokeratin 10
CK 10
RP23-336D20.2
Krt1 X
Krt1 Xs
keratin complex 1, acidic, gene 10
K10
epidermal keratin X
BIE
EHK
KPP
BCIE
CK10
CK-10

GO ID 0046982
0030280
0070268
0031424
0030216
0018149
0045684
0051290
0009986
0001533
0005737
0005829
0070062
0005615
0005882
0016020
0005634
0071277
0045095

KEGG ID hsa:3858

Organism Homo sapiens {Organism urn:agi-taxid:9606}
Homo sapiens

OMIM ID 148080
113800
609165
607602

Hugo ID 6413
HGNC:6413

Human chromosome position 17q21.2
17q21

Swiss-Prot Accession P13645
P13645.6
Q14664
Q8N175

PIR ID A31994
S02158

GenBank ID NC_000017
XM_005257343
XP_005257400
NM_000421
NP_000412
NG_008405
AC090283
CH471152
EAW60680
EAW60681
L20218
AAB59438
L20219
AAB59439
X14487
CAA32649
BC034697
AAH34697
CU455823
J04029
AAA60544
M19156
AAA59468
M77663
AAA59199
P13645
NG_033147
NC_018928
AMYH02033404
DQ893356
ABM84282
DQ896675
ABM87674
AC_000149
ABBA01031821

Swiss-Prot ID K1C10_HUMAN

Cell Localization Secreted
Extracellular space
Cell surface

Ensembl ID ENSG00000186395
ENSP00000269576.5
ENST00000269576.6
ENSP00000269576
ENST00000269576

Unigene ID Hs.99936