Pathway
|
Osteoarthritis
|
|
Skin Aging
|
|
Plasmin Effects in Inflammation
|
|
Bradykinin Effects in Inflammation
|
|
Nociception Expression Targets Signaling
|
|
CCR1 Expression Targets
|
|
Scavenger Receptor OLR1 in Inflammation Related Endothelial Dysfunction
|
|
Proteins Involved in Dilated Cardiomyopathy
|
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Proteins Involved in Arterial Hypertension
|
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Myocardial Remodeling
|
|
Myocardial Infarction
|
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Proteins with Altered Expression in Melanoma
|
|
Melanoma
|
|
Proteins Involved in Melanoma
|
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IL17 Signaling in Psoriasis
|
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IL22 Induces Keratinocyte Proliferation in Psoriasis
|
|
Proteins with Altered Expression in Psoriasis
|
|
TGF-beta Signaling in Skin Aging
|
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Proteins Involved in Photoaging
|
|
Extracellular Matrix Degradation in Skin Aging
|
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Proteins Involved in Colorectal Neoplasms
|
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TNF and IL1B Induce Metalloproteinase Synthesis in Osteoarthritis
|
|
Proteins Involved in Osteoarthritis
|
|
Proteins Involved in Polycystic Ovary Syndrome
|
|
Synovial Fibroblast Activation in Psoriatic Arthritis
|
|
Keratinocyte Activation in Psoriatic Arthritis
|
|
Synovial Fibroblast Activation by Citokines in Rheumatoid Arthritis
|
|
TLR2 Induced Synovial Fibroblast Activation in Rheumatoid Arthritis
|
|
Proteins Involved in Rheumatoid Arthritis
|
|
Proteins Involved in Systemic Scleroderma
|
|
Skin Fibrosis
|
|
Cathepsins Role in Periodontitis
|
|
Proteins Involved in Periodontitis
|
|
Proteins Involved in Astrocytoma
|
|
Glioma Invasion Signaling
|
|
Proteins Involved in Glioma
|
|
Proteins Involved in Adhesion, Migration and Invasion of Endometriotic Cell
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|
Proteins Involved in Endometriosis
|
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Proteins with Altered Expression in Endometriosis
|
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Proteins Involved in Age-Related Macular Degeneration
|
|
PGF2-alpha Effect on Treatment
|
|
Proteins Involved in Chronic Obstructive Pulmonary Disease
|
|
Alveolar Epithelial Cell Dysfunction in COPD
|
|
Noradrenaline/Gs Expression Targets
|
|
Serotonin/Gs Expression Targets
|
|
Noreadrenaline/Gq Expression Targets
|
|
Epinephrine/Gs Expression Targets
|
|
Acetylcholine Expression Targets
|
|
Serotonin/Gq Expression Targets
|
|
Epinephrine/Gq Expression Targets
|
|
Elevated Receptors -> Expression Targets in Heart
|
|
CXCL12 Expression Targets
|
|
CCL3 Expression Targets
|
|
CSF2 -> NF-kB Expression Targets
|
|
CSF2 -> STAT Expression Targets
|
|
LIF Expression Targets
|
|
EGF -> CTNN Expression Targets
|
|
EGF -> AP-1/ATF Expression Targets
|
|
EGF -> CREB/CREBBP/ELK/SRF/MYC Expression Targets
|
|
EGF -> MEF/MYOD/NFATC Expression Targets
|
|
EGF -> STAT Expression Targets
|
|
Erythropoietin -> NF-kB Expression Targets
|
|
Erythropoietin -> AP-1/MYC/CREB Expression Targets
|
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Erythropoietin -> STAT Expression Targets
|
|
Erythropoietin -> ELK/SRF Expression Targets
|
|
F2 -> AP-1/CREB/ELK/SRF/SP1 Expression Targets
|
|
F2 -> STAT1/NF-kB Expression Targets
|
|
PLG -> AP-1/CREB/ELK/SRF/SP1 Expression Targets
|
|
PLG -> STAT1/NF-kB Expression Targets
|
|
FGF2 -> STAT Expression Targets
|
|
FGF1 -> AP-1/CREB/ELK/SRF/MYC Expression Targets
|
|
FGF1 -> STAT Expression Targets
|
|
FGF7 -> AP-1/CREB/CREBBP/MYC Expression Targets
|
|
FGF2 -> AP-1/CREB/CREBBP/ELK/SRF/MYC Expression Targets
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|
HGF -> STAT Expression Targets
|
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HGF -> AP-1/CREB/ELK/SRF/MYC Expression Targets
|
|
EGFR Transactivation in Cancer and Non-Cancer Cells
|
|
Proteins with Altered Expression in Cancer Metastases
|
|
BSG (CD147) in Cancer Cells Motility, Invasion and Survival
|
|
IGF1 -> CEBPA/FOXO1A Expression Targets
|
|
Insulin -> STAT Expression Targets
|
|
Insulin -> CEBPA/CTNNB/FOXA/FOXO Expression Targets
|
|
Insulin -> MEF/MYOD Expression Targets
|
|
Insulin -> ELK/SRF/HIF1A/MYC/SREBF Expression Targets
|
|
CTGF -> AP-1/CREB/MYC Expression Targets
|
|
IL6 Expression Targets
|
|
IL10 Expression Targets
|
|
IL22 Expression Targets
|
|
IL11 Expression Targets
|
|
Prostaglandin F Expression Targets
|
|
PAF/Gq -> AP-1/ATF1/CREB/ERK/SRF Expression Targets
|
|
PGE1 Expression Targets
|
|
CD40 -> Expression Targets in Thymus
|
|
Elevated Receptors -> Expression Targets in Muscle
|
|
OSM/OSMR Expression Targets
|
|
PDGFD -> AP-1 Expression Targets
|
|
PDGFD -> STAT Expression Targets
|
|
PDGF -> AP-1/CREB/CREBBP/MYC Expression Targets
|
|
PDGF -> STAT Expression Targets
|
|
OXT Expression Targets
|
|
POMC Expression Targets
|
|
EDN1 Expression Targets
|
|
AGT -> STAT Expression Targets
|
|
PRL/PRLR Expression Targets
|
|
PRL/GHR -> STAT Expression Targets
|
|
PRL/GHR -> NF/kB/ELK/SRF/MYC Expression Targets
|
|
PAF Expression Targets
|
|
TGFA -> STAT Expression Targets
|
|
TGFA -> CTNNB/CTNND Expression Targets
|
|
TGFA/AP-1/ATF Expression Targets
|
|
TGFA -> CREB/CREBBP/ELK-SRF/MYC Expression Targets
|
|
TGFB2-TGFBR1 Expression Targets
|
|
TGFB1-TGFBR1 Expression Targets
|
|
TGFB2-TGFBR2 Expression Targets
|
|
TGFB1-TGFBR2 Expression Targets
|
|
TGFB1-ACVRL1 Expression Targets
|
|
TNF -> NF-kB Expression Targets
|
|
TNF -> AP-1 Expression Targets
|
|
CD40LG -> STAT Expression Targets
|
|
TNF -> STAT Expression Targets
|
|
TLR4 -> AP-1 Expression Targets
|
|
TLR5 Expression Targets
|
|
IL1B -> NO Expression Targets
|
|
TLR1 -> 2/6 Expression Targets
|
|
IL1B Expression Targets
|
|
TLR4 -> NF-kB/IRF Expression Targets
|
|
IL1A Expression Targets
|
|
PLAU -> STAT1 Expression Targets
|
|
PLAU -> ELK-SRF/AP-1 Expression Targets
|
|
VEGFA -> ATF/CREB/ELK-SRF Expression Targets
|
|
VEGFA -> STAT Expression Targets
|
|
VEGFA -> AP-1/CREBBP/MYC Expression Targets
|
|
VEGFA -> CTNNB/CTNND Expression Targets
|
|
WNT5A Expression Targets
|
|
ace2
|
|
pprarg neg, uknown targets, ps-positive
|
|
prarg neg,ukn expres targets, ps-positive
|
|
PPARG negative targets
|
|
pparg expr target_regulators
|
|
Neighbors of disease exacerbation
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|
Neighbors of tumor progression
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Neighbors of cancer progression
|
|
Neighbors of overall survival
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|
Neighbors of disease severity
|
|
Neighbors of tumor size
|
|
Neighbors of lesion size
|
|
Neighbors of mortality
|
|
Neighbors of survival time
|
|
Neighbors of functional recovery
|
|
Neighbors of cancer survival
|
|
Neighbors of clinical stage
|
|
Neighbors of lethality
|
|
Neighbors of recurrence-free survival
|
|
Neighbors of disease-free survival
|
|
Neighbors of treatment outcome
|
|
Neighbors of tumor recurrence
|
|
Neighbors of tumor promotion
|
|
Neighbors of morbidity
|
|
Neighbors of bone mineral density
|
|
Neighbors of adverse outcome
|
|
Neighbors of cell density
|
|
Neighbors of cancer-specific survival
|
|
Neighbors of shear stress
|
|
Neighbors of blood pressure
|
|
Neighbors of tumor grade
|
|
Neighbors of vascular reactivity
|
|
Neighbors of body mass index
|
|
Neighbors of cancer risk
|
|
Neighbors of cancer incidence
|
|
Neighbors of ejection fraction
|
|
Neighbors of vascular tone
|
|
Neighbors of left ventricular ejection fraction
|
|
Neighbors of breast cancer risk
|
|
Neighbors of pathological response
|
|
Neighbors of disease exacerbation
|
|
Neighbors of tumor progression
|
|
Neighbors of cancer progression
|
|
Neighbors of overall survival
|
|
Neighbors of disease severity
|
|
Neighbors of tumor size
|
|
Neighbors of lesion size
|
|
Neighbors of mortality
|
|
Neighbors of survival time
|
|
Neighbors of functional recovery
|
|
Neighbors of cancer survival
|
|
Neighbors of clinical stage
|
|
Neighbors of lethality
|
|
Neighbors of recurrence-free survival
|
|
Neighbors of disease-free survival
|
|
Neighbors of treatment outcome
|
|
Neighbors of tumor recurrence
|
|
Neighbors of tumor promotion
|
|
Neighbors of morbidity
|
|
Neighbors of bone mineral density
|
|
Neighbors of adverse outcome
|
|
Neighbors of cell density
|
|
Neighbors of cancer-specific survival
|
|
Neighbors of shear stress
|
|
Neighbors of blood pressure
|
|
Neighbors of tumor grade
|
|
Neighbors of vascular reactivity
|
|
Neighbors of body mass index
|
|
Neighbors of cancer risk
|
|
Neighbors of cancer incidence
|
|
Neighbors of ejection fraction
|
|
Neighbors of vascular tone
|
|
Neighbors of left ventricular ejection fraction
|
|
Neighbors of breast cancer risk
|
|
Neighbors of pathological response
|
|
Neighbors of immune response
|
|
Neighbors of inflammatory response
|
|
Neighbors of wound healing
|
|
Neighbors of angiogenesis
|
|
Neighbors of innate immune response
|
|
Neighbors of cell function
|
|
Neighbors of cell formation
|
|
Neighbors of osteoclast development
|
|
Neighbors of epithelial to mesenchymal transition
|
|
Neighbors of immunity
|
|
Neighbors of cell proliferative response
|
|
Neighbors of chemotaxis
|
|
Neighbors of cell survival
|
|
Neighbors of osteoclast differentiation
|
|
Neighbors of cell phenotype
|
|
Neighbors of T-cell proliferation
|
|
Neighbors of tissue remodeling
|
|
Neighbors of cell adhesion
|
|
Neighbors of endothelial cell proliferation
|
|
Neighbors of fibrogenesis
|
|
Neighbors of tumor growth
|
|
Neighbors of tissue repair
|
|
Neighbors of cell infiltration
|
|
Neighbors of cell interaction
|
|
Neighbors of SMC proliferation
|
|
Neighbors of lumen formation
|
|
Neighbors of endothelial cell migration
|
|
Neighbors of lipid storage
|
|
Neighbors of pregnancy
|
|
Neighbors of aging
|
|
Neighbors of cell motility
|
|
Neighbors of bone resorption
|
|
Neighbors of monocyte migration
|
|
Neighbors of fibroblast proliferation
|
|
Neighbors of adipocyte differentiation
|
|
Neighbors of regeneration
|
|
Neighbors of cell migration
|
|
Neighbors of cancer growth
|
|
Neighbors of stem cell proliferation
|
|
Neighbors of smooth muscle cell migration
|
|
Neighbors of hepatic regeneration
|
|
Neighbors of transendothelial migration
|
|
Neighbors of leukocyte migration
|
|
Neighbors of monocyte recruitment
|
|
Neighbors of cell invasion
|
|
Neighbors of heart function
|
|
Neighbors of bone remodeling
|
|
Neighbors of ossification
|
|
Neighbors of lung development
|
|
Neighbors of autophagy
|
|
Neighbors of transcription activation
|
|
Neighbors of senescence
|
|
Neighbors of hepatocyte proliferation
|
|
Neighbors of endothelial cell function
|
|
Neighbors of neuronal death
|
|
Neighbors of cell growth
|
|
Neighbors of ROS generation
|
|
Neighbors of epithelial cell proliferation
|
|
Neighbors of cancer cell growth
|
|
Neighbors of hemato-encephalic barrier
|
|
Neighbors of cellular senescence
|
|
Neighbors of colony formation
|
|
Neighbors of cell differentiation
|
|
Neighbors of stem cell migration
|
|
Neighbors of psoriasis
|
|
Neighbors of inflammatory disease
|
|
Neighbors of rheumatoid arthritis
|
|
Neighbors of atherosclerosis
|
|
Neighbors of fibrosis
|
|
Neighbors of colitis
|
|
Neighbors of arthritis
|
|
Neighbors of injury
|
|
Neighbors of atherogenesis
|
|
Neighbors of vascular remodeling
|
|
Neighbors of metastasis
|
|
Neighbors of carcinogenesis
|
|
Neighbors of multiple sclerosis
|
|
Neighbors of chronic inflammation
|
|
Neighbors of inflammation
|
|
Neighbors of tumor microenvironment
|
|
Neighbors of pathological angiogenesis
|
|
Neighbors of obesity
|
|
Neighbors of vascular disease
|
|
Neighbors of diabetes mellitus
|
|
Neighbors of asthma
|
|
Neighbors of hyperplasia
|
|
Neighbors of osteoarthritis
|
|
Neighbors of liver fibrosis
|
|
Neighbors of chronic obstructive pulmonary disease
|
|
Neighbors of myocardial infarction
|
|
Neighbors of leukocyte infiltration
|
|
Neighbors of reperfusion injury
|
|
Neighbors of airway inflammation
|
|
Neighbors of hepatitis
|
|
Neighbors of infection
|
|
Neighbors of vascular injury
|
|
Neighbors of preeclampsia
|
|
Neighbors of macrophage infiltration
|
|
Neighbors of liver injury
|
|
Neighbors of sepsis
|
|
Neighbors of death
|
|
Neighbors of autoimmune disease
|
|
Neighbors of ischemic stroke
|
|
Neighbors of dermatitis
|
|
Neighbors of heart disease
|
|
Neighbors of lung injury
|
|
Neighbors of immunopathology
|
|
Neighbors of systemic sclerosis
|
|
Neighbors of hepatocellular carcinoma
|
|
Neighbors of gastric cancer
|
|
Neighbors of atherosclerotic plaque
|
|
Neighbors of colorectal cancer
|
|
Neighbors of cardiac remodeling
|
|
Neighbors of breast cancer
|
|
Neighbors of melanoma
|
|
Neighbors of cartilage degeneration
|
|
Neighbors of interstitial fibrosis
|
|
Neighbors of neoplasm invasion
|
|
Neighbors of heart failure
|
|
Neighbors of pulmonary fibrosis
|
|
Neighbors of cancer
|
|
Neighbors of type 2 diabetes
|
|
Neighbors of neoplasm
|
|
Neighbors of endometriosis
|
|
Neighbors of myocardial fibrosis
|
|
Neighbors of coronary artery disease
|
|
Neighbors of rupture
|
|
Neighbors of prostate cancer
|
|
Neighbors of hypertrophy
|
|
Neighbors of osteolysis
|
|
Neighbors of ovarian cancer
|
|
Neighbors of pancreatic cancer
|
|
Neighbors of hypertension
|
|
Neighbors of epithelial cell
|
|
Neighbors of keratinocyte
|
|
Neighbors of vascular smooth muscle cell
|
|
Neighbors of umbilical vein endothelial cell
|
|
Neighbors of monocyte
|
|
Neighbors of endometrial stromal cell
|
|
Neighbors of alveolar macrophage
|
|
Neighbors of synoviocyte
|
|
Neighbors of macrophage
|
|
Neighbors of adipocyte
|
|
Neighbors of activated monocyte
|
|
Neighbors of fibroblast
|
|
Neighbors of airway epithelial cell
|
|
Neighbors of PBMC
|
|
Neighbors of stromal cell
|
|
Neighbors of airway smooth muscle cell
|
|
Neighbors of osteoblast
|
|
Neighbors of pneumocyte
|
|
Neighbors of endometrium cell
|
|
Neighbors of microglia
|
|
Neighbors of trophoblast
|
|
Neighbors of mononuclear cell
|
|
Neighbors of hepatic stellate cell
|
|
Neighbors of hepatocyte
|
|
Neighbors of decidual cell
|
|
Neighbors of kidney mesangial cell
|
|
Neighbors of endothelial cell
|
|
Neighbors of dendritic cell
|
|
Neighbors of Kuppfer cell
|
|
Neighbors of proadipocyte
|
|
Neighbors of inflammatory cell
|
|
Neighbors of osteoclast
|
|
Neighbors of neutrophil
|
|
Neighbors of smooth muscle myocyte
|
|
Neighbors of astrocyte
|
|
Neighbors of lung fibroblast
|
|
Neighbors of mesothelial cell
|
|
Neighbors of mononuclear phagocyte
|
|
Neighbors of capillary endothelial cell
|
|
Neighbors of granulocyte
|
|
Neighbors of myeloid cell
|
|
Neighbors of mesenchymal stroma cell
|
|
Neighbors of corneal epithelial cell
|
|
Neighbors of stem cell
|
|
Neighbors of tumor infiltrating macrophage
|
|
Neighbors of granulosa cell
|
|
Neighbors of leukocyte
|
|
Neighbors of chondrocyte
|
|
Neighbors of mesenchymal cell
|
|
Neighbors of T-cell
|
|
Neighbors of M1 macrophage
|
|
Neighbors of myofibroblast
|
|
Neighbors of mast cell
|
|
Neighbors of bone marrow stromal cell
|
|
Neighbors of aortic smooth muscle cell
|
|
Neighbors of mammary epithelial cell
|
|
Neighbors of phagocyte
|
|
Neighbors of kidney cell
|
|
Neighbors of M2 macrophage
|
|
Neighbors of blood cell
|
|
Neighbors of skin cell
|
|
Neighbors of luteal cell
|
|
Neighbors of lung
|
|
Neighbors of liver
|
|
Neighbors of skin
|
|
Neighbors of lymph node
|
|
Neighbors of airway
|
|
Neighbors of aorta
|
|
Neighbors of bone
|
|
Neighbors of carotid artery
|
|
Neighbors of synovial membrane
|
|
Neighbors of esophagus
|
|
Neighbors of retina
|
|
Neighbors of brain
|
|
Neighbors of ovary
|
|
Neighbors of breast
|
|
Neighbors of stomach
|
|
Neighbors of pancreas
|
|
Neighbors of lymphatic system
|
|
Neighbors of colorectal region
|
|
Neighbors of allantois
|
|
Neighbors of uterine cervix
|
|
Neighbors of nose
|
|
Neighbors of eye
|
|
Neighbors of cornea
|
|
Neighbors of periodontal ligament
|
|
Neighbors of hip region
|
|
Neighbors of NF-kB family
|
|
Neighbors of oxidized LDL
|
|
Neighbors of JNK
|
|
Neighbors of IL1 family
|
|
Neighbors of PPAR
|
|
Neighbors of Jun/Fos
|
|
Neighbors of NFKBI
|
|
Neighbors of PKC
|
|
Neighbors of PI3K
|
|
Neighbors of STAT family
|
|
Neighbors of mitogen-activated protein kinase
|
|
Neighbors of IFNAR ligand
|
|
Neighbors of transforming growth factor
|
|
Neighbors of TLR
|
|
Neighbors of cytokine
|
|
Neighbors of interferon
|
|
Neighbors of interleukin
|
|
Neighbors of JAK
|
|
Neighbors of MEK1/2
|
|
Neighbors of PDGF
|
|
Neighbors of Ras GTPase
|
|
Neighbors of ERK1/2
|
|
Neighbors of growth factor
|
|
Neighbors of PKA
|
|
Neighbors of ovalbumin
|
|
Neighbors of LDL
|
|
Neighbors of NF-AT family
|
|
Neighbors of chorionic gonadotropin
|
|
Neighbors of adipokine
|
|
Neighbors of protein tyrosine kinase
|
|
Neighbors of NAD(P)H oxidase
|
|
Neighbors of SMAD subfamily
|
|
Neighbors of AMPK
|
|
Neighbors of HDL
|
|
Neighbors of p38
|
|
Neighbors of inflammatory cytokine
|
|
Neighbors of IL23
|
|
Neighbors of estrogen receptor
|
|
Neighbors of histone deacetylase
|
|
Neighbors of PDGF-BB
|
|
Neighbors of IL1R
|
|
Neighbors of HIF-1
|
|
Neighbors of IL12
|
|
Neighbors of Notch
|
|
Neighbors of prostaglandin-endoperoxide synthase
|
|
Neighbors of mitogen-activated protein kinase kinase
|
|
Neighbors of TSH
|
|
Neighbors of endothelin
|
|
Neighbors of NOS
|
|
Neighbors of superoxide dismutase
|
|
Neighbors of proteasome endopeptidase complex
|
|
Neighbors of class nuclear receptor with C4 zinc fingers
|
|
Neighbors of histone H3
|
|
Neighbors of vitronectin receptor (integrin)
|
|
Neighbors of PP2A
|
|
Neighbors of retinoid-X receptor subfamily
|
|
Neighbors of SAPK
|
|
Neighbors of WNT
|
|
Neighbors of gonadotropins
|
|
Neighbors of immunoglobulin
|
|
Neighbors of AHR subfamily
|
|
Neighbors of ITG
|
|
Neighbors of relaxin
|
|
Neighbors of TLR1/2 heterodimer
|
|
Neighbors of FSH
|
|
Neighbors of angiotensin receptor
|
|
Neighbors of RA receptor
|
|
Neighbors of Rho kinase
|
|
Neighbors of PDGF receptor
|
|
Neighbors of neuropeptides
|
|
Neighbors of histone acetyltransferase
|
|
2_Interleukin-17 and interleukin-22 signaling in psoriasis
|
|
1_TNF and IL1B provoke ECM degradation in osteoarthritis
|
|
2_Oxidized LDL causes endothelial dysfunction in atherosclerosis
|
|
1_Cigarette smoke causes dysfunction and production of inflammatory mediators in alveolar epithelial cells
|
|
1_2_Feedback relations between coagulation and fibrinolysis
|
|
drug-target moltransport
|
|
Interleukin-17 and interleukin-22 signaling in psoriasis
|