Protein SOS1

URN urn:agi-llid:6654
Total Entities 0
Connectivity 667
Name SOS1
Description son of sevenless homolog 1 (Drosophila)
Notes This gene encodes a protein that is a guanine nucleotide exchange factor for RAS proteins, membrane proteins that bind guanine nucleotides and participate in signal transduction pathways. GTP binding activates and GTP hydrolysis inactivates RAS proteins. The product of this gene may regulate RAS proteins by facilitating the exchange of GTP for GDP. Mutations in this gene are associated with gingival fibromatosis 1 and Noonan syndrome type 4. [provided by RefSeq, Jul 2008]
Primary Cell Localization Cytoplasm

Pathway Alzheimer's Disease
Osteoarthritis
Skin Aging
mTOR Signaling
mTOR Signaling Hyperfunction
Insulin Influence on Protein Synthesis
Insulin Influence on Glycogenesis
Thyroid Hormones Common non-Genomic Effects in Hyperthyroidism
Insulin Signaling
Thrombopoietin Receptors Signaling in Platelet Maturation
T-Cell Dependent B-Cell Activation
Natural Killer Cell Activation through C-Type Lectin-like Receptors
Natural Killer Cell Activation through ITAM-Containing Receptors
Natural Killer Cell Activation through Integrins and non-ITAM-Containing Receptors
T-Cell Maturation (Hypothesis)
Natural Killer Cell Activation
T-Cell Positive Selection and Neglect Induced Death
T-Cell Central Tolerance
CD8+ T-Cell Activation
Th1-Cell Differentiation
Treg-Cell Differentiation
Th2-Cell Differentiation
T-Cell Receptor Signaling
CXC Chemokine Receptor Signaling
CC Chemokine Receptor Signaling
Platelet Activation via Adhesion Molecules
Proplatelet Maturation
Toll-like Receptor Independent Sterile Inflammation
Basophil Activation
Eosinophil Survival by Cytokine Signaling
Mast-Cell Activation via IgE Signaling
Mast-Cells De Novo Synthesized Mediators via IgE Independent Signaling
CD16/CD14 Proinflammatory Monocyte Activation
Macrophage M2-Related Phagocytosis
anti-Inflammatory Function of Macrophage M2 Lineage
Neutrophil Recruitment and Priming
Neutrophil Degranulation via FPR1 Signaling
Neutrophil Chemotaxis
Negative Acute Phase Proteins Synthesis
Positive Acute Phase Proteins Synthesis
Vascular Smooth Muscle Cell/Pericyte Migration and Proliferation
Vascular Endothelial Cell Activation by Growth Factors
Dendritic Spine Morphogenesis and Stabilization
Nociception Expression Targets Signaling
NTSR1 Expression Targets
DRD2 Expression Targets
CHRM1 -> IL2 Production
IL6 Expression Targets -> Nociception
CHRNA7 -> NOS1 Production
Vitamine D Deficite and Dentin Formation
Th1-Cells Activation and Proliferation in Atherosclerosis
Arterial Hypertension
Endothelial Cell Dysfunction in Arterial Hypertension
Smooth Muscle Cell Dysfunction in Arterial Hypertension
Smooth Muscle Cell Dysfunction in Pulmonary Hypertension
Myocardial Remodeling
Sebocyte Proliferation in Acne Vulgaris
Inflammatory Reaction in Acne Vulgaris
Hair Follicle Keratinocyte Apoptosis
Androgens in Sebocyte Maturation
Atopic Dermatitis Onset
Mast-Cells Activation in Atopic Dermatitis
IL22 Induces Keratinocyte Proliferation in Psoriasis
Th0-Cell Aberrant Activation in Systemic Lupus Erythematosus
Th1-Cell Function in Systemic Lupus Erythematosus
Th2-Cell Function in Systemic Lupus Erythematosus
Acute Cytotoxic CD8+T-Cell Response against Melanocytes
T-Cell Cytotoxic Response against Melanocytes in Vitiligo
Humoral Immunity in Vitiligo
CD8+ T-Cell Response to Self-Determinants in Diabetes
Treg-Cell Function in Diabetes Mellitus Type 1
Natural Killer T-Cell Roles in Diabetes Mellitus Type 1
non-Suppressive Treg-Cell in Diabetes Mellitus Type 1
TLR2 Signaling in Treg-Cell in Type 1 Diabetes (Animal Model)
Natural Killer Cell in Diabetes Mellitus Type 1
Peripheral Tolerance to Autoantigens Recession in Diabetes Mellitus Type 1
Treg-Cell Activation in Diabetes Mellitus
Donohue Syndrome Progression (Hypothesis)
Tubular Cell Dysfunction in Progressive Diabetic Nephropathy
Endothelial Cell Dysfunction in Progressive Diabetic Nephropathy
Mesangial Cell Dysfunction in Diabetic Nephropathy
Adiponectin Synthesis Declines in Insulin Resistance
Insulin Resistance in Hepatocytes
Hepatic Stellate Cells in non-Alcoholic Fatty Liver Disease
FOXO1 and SREBP-1C Role in beta-Cell Suppression (Rodent Model)
RET1 Mutation in Hyperparathyroidism
Cardiovascular Effects in Hyperthyroidism
CD4+T-Cell Response in Celiac Disease
CD8+ T-Cell Response in Celiac Disease
Celiac Disease
Cetuximab Resistance in Colorectal Cancer
Metastatic Colorectal Cancer
CagA Phosphorylation Dependent Signaling
EDN, NRG, NRTN, and GDNF/RET Signaling in Hirschsprung Disease
Th2-Cell Function in Ulcerative Colitis
T-Cell Cytotoxic Response in Ulcerative Colitis
FLT3/KIT/MLL Signaling in Leukemia
Apoptosis Block in Acute Myeloid Leukemia Cell
RARA Signaling in Acute Myeloid Leukemia (M3)
Acute Myeloid Leukemia
Myeloid Cell Differentiation Block in Leukemia
B-Cell Acute Lymphoblastic Leukemia
B-Cell Chronic Lymphocytic Leukemia
Chronic Myeloid Leukemia
Follicular Lymphoma
IL6/IGF1/VEGFA Signaling in Multiple Myeloma
Multiple Myeloma
T-Cell Acute Lymphoblastic Leukemia
Hepatocellular Carcinoma
Growth Factor Signaling in Hepatocellular Carcinoma
Pancreatic Ductal Carcinoma
Growth Factor Signaling in Pancreatic Neoplasms
Pancreatic Neuroendocrine Tumors
TGFBR Signaling in Pancreatic Neoplasms
Airway Smooth Muscle Cell High Rate Proliferation
IgE Induces Airway Smooth Muscle Cell Proliferation
Goblet-Cell Related Mucus Secretion in Asthma
Basophil Activation in Asthma
Mast-Cell Activation in Asthma
Antigen-Presenting Cell Role in Asthma
Th2-Cell Response in Asthma
Mucin Production in Goblet Airway Epithelial Cells
CFTR Facilitates Oxidative Stress in Airway Epithelium in CF
TNF and IL1B Induce Metalloproteinase Synthesis in Osteoarthritis
Steroidogenesis Impairement in Polycystic Ovary Syndrome
Polycystic Ovary Syndrome
PTPN22 Role in Rheumatoid Arthritis
Synovial Fibroblast Proliferation in Rheumatoid Arthritis
B-Cells Function in Systemic Scleroderma
Th2-Cells Function in Systemic Scleroderma
Skin Fibrosis
CD8+ T-Cell Action Impairment in HIV Type 1 Infection
CD4+ T-Cell Function Decline in HIV
CD4+ T-Cell Death in HIV
Estrogen Effects on Pregnancy Gingivitis
IL1 Receptor Antagonist (IL1RN) Deficiency (DIRA)
Cowden Syndrome
Gluten Impact on Neuronal System (Hypothesis)
Rett Syndrome
IL6 Promotes Inflammation in Muscular Dystrophies
Muscular Dystrophies
Dystrophin Glycoprotein Complex Signaling in Muscular Dystrophies
Osteoblast Function Decline in Osteoporosis
APP and Glutamate Signaling Cause Neuronal Dysfunction in Alzheimer Disease
Glioblastoma, Primary
Glioblastoma, Secondary
Astrocytoma
Glioma Invasion Signaling
Growth Factor Signaling in Neuroblastoma
Neuroblastoma
SPP1 Induced Survival of Myelin Specific T-Cells in Multiple Sclerosis
ERBB/VEGFR/Akt Signaling in Breast Cancer
IGF1R/AKT Signaling in Breast Cancer
ESR1/ERBB Positive Luminal Breast Cancer
Breast Cancer
Endometrial Cancer
Endometrioid Endometrial Cancer
Clear Cell Endometrial Cancer and Papillary Serous Endometrial Cancer
Angiogenesis in Endometriosis
Leptin Role in Endometriosis
Endometrioid Ovarian Carcinoma
Clear Cell Ovarian Carcinoma
EGFR and PTAFR Signaling in Ovarian Cancer
High-Grade Serous Ovarian Carcinoma
Low-Grade Serous Ovarian Carcinoma
Ovarian Cancer
Mucinous Ovarian Carcinoma
Subepithelial Fibroblasts in Middle Ear Cholesteatoma
Cholesteatoma
Prostate Cancer
Steroids Induced Cataract
Glutamate Mediated Excitotoxicity in Glaucoma
Cytokines Trigger Otitis Media
Mucin Hyperproduction in Goblet and Mucous Cells
Mesangial Cell Dysfunction in Glomerulonephritis
Interstitial Fibroblasts in Pyelonephritis
CD38/CD3 -> JUN/FOS/NF-kB Signaling in T-cell Proliferation
CD38/CD19 -> JUN/FOS/NF-kB Signaling in B-cell Proliferation
AREG -> CREB/CREBBP Expression Targets
AREG -> NCOR2 Expression Targets
AREG -> SMAD1 Expression Target
AREG -> HIF1A Expression Targets
AREG -> AP-1 Expression Targets
Noreadrenaline/Gq Expression Targets
Acetylcholine Expression Targets
Epinephrine/Gq Expression Targets
Dopamine/Gi Expression Targets
BTC -> AP-1/ATF/CREB Expression Targets
BTC -> EP300/ETS/ETV/SP1 Expression Targets
SELE -> ELK-SRF Signaling
CD247 Expression Targets
FCGR3A Expression Targets
CD72 -> CREB/CREBBP Expression Targets
CD8 -> ATF/CREB/CREBBP Expression Targets
CD80 -> NF-kB Expression Targets
CD86 -> NF-kB Expression Targets
CHRNA7 -> CREB Signaling
EGF -> HIF1A Expression Targets
EGF -> AP-1/ATF Expression Targets
EGF -> CREB/CREBBP/ELK/SRF/MYC Expression Targets
EGF -> TP53 Expression Targets
EGF -> NCOR2 Expression Target
EGFR -> NCOR2 Signaling
EGFR/ERBB2 -> TP53 Signaling
ERBB2/3 -> EP300/ETS/ETV/SP1 Signaling
EGFR -> SMAD1 Signaling
EGFR/ERBB2 -> HIF1A Signaling
EGFR -> AP-1/ATF2 Signaling
EGFR -> AP-1/CREB/ELK/SRF/MYC Signaling
EREG -> CREB Expression Target
EREG -> EP300/SP1 Expression Targets
EREG -> HIF1A Expression Target
EREG -> AP-1/ATF Expression Targets
Erythropoietin -> ELK/SRF Expression Targets
PECAM1 Expression Targets
NCAM1 Expression Targets
F2 -> AP-1/CREB/ELK/SRF/SP1 Expression Targets
PLG -> AP-1/CREB/ELK/SRF/SP1 Expression Targets
FGF9 -> AP-1/CREB/MYC Expression Targets
FGF10 -> AP-1/CREB/CREBBP/MYC Expression Targets
FGF1 -> AP-1/CREB/ELK/SRF/MYC Expression Targets
FGF1 -> NCOR2 Expression Target
FGF7 -> RUNX Expression Targets
FGF8 -> AP-1/CREB/MYC Expression Targets
FGF1 -> RUNX Expression Targets
FGF18 -> AP-1/CREB Expression Targets
FGF23 -> NCOR2 Expression Targets
FGF8 -> RUNX Expression Targets
FGF9 -> RUNX Expression Targets
FGF2 -> NCOR2 Expression Targets
FGF4 -> AP-1/MYC Expression Targets
FGF7 -> AP-1/CREB/CREBBP/MYC Expression Targets
FGF2 -> RUNX Expression Targets
FGF2 -> AP-1/CREB/CREBBP/ELK/SRF/MYC Expression Targets
FGFR -> RUNX2 Signaling
FGFR -> AP-1/CREB/CREBBP/ELK/SRF/MYC Signaling
Glutamate/Gq Expression Targets
GH1/GHR -> NF-kB/ELK/SRF/MYC Expression Targets
CSH1/GHR Expression Targets
HBEGF -> AP-1/ATF Expression Targets
HBEGF -> TP53 Expression Targets
HBEGF -> EP300/ETS/ETV/SP1 Expression Targets
HBEGF -> HIF1A Expression Targets
HBEGF -> CREB/MYC Expression Targets
HGF -> AP-1/CREB/ELK/SRF/MYC Expression Targets
HGFR -> AP-1/CREB/MYC Signaling
TAM Receptor Signaling Activation in Cancer
TGFB Signaling activation by Blocking of Tumor Suppressors
VEGFA Dependent Angiogenesis in Cancer
VEGF Independent Angiogenesis in Cancer
Integrins in Cancer Cell Motility, Invasion and Survival
CDH2 Activation Promotes Cancer Cell Migration and Survival
TGFB Family in Epithelial to Mesenchymal Transition in Cancer
Treg Cells Promote Immunosuppression in Cancer Immune Escape
IGF2 -> HIF1A/MYC Expression Targets
IGF1 -> ELK/SRF/HIF1A/MYC/SREBF Expression Targets
Insulin -> ELK/SRF/HIF1A/MYC/SREBF Expression Targets
NCAM1 -> CREB/ELK/SRF/MYC Signaling
PECAM -> SP1 Signaling
FcIgER -> ELK-SRF Signaling
IGF1R -> ELK/SRF/HIF1A/MYC/SREBF Signaling
InsulinR -> ELK/SRF/SREBF Signaling
FibronectinR -> AP-1/ELK/SRF/SREBF Signaling
Fibronectin Expression Targets
CTGF -> AP-1/CREB/MYC Expression Targets
CTGF -> NCOR2 Expression Target
IL6R -> CEBP/ELK/SRF Signaling
IL2R -> ELK/SRF/MYC Signaling
IL4R -> ELK/SRF/HMGY Signaling
IL16 -> AP-1 Expression Targets
IL6 Expression Targets
IL4 Expression Targets
IL2 Expression Targets
UrokinaseR -> ELK/SRF Signaling
PTPRC -> BCL6 Expression Targets
Leptin -> ELK/SRF Expression Targets
LPA Expression Targets
NRG1 -> EP300/ETS/ETV/SP1 Expression Targets
NRG1 -> CREB/CREBBP/ELK/SRF/MYC Expression Targets
NRG1 -> TP53 Expression Target
NRG1 -> AP-1/ATF Expression Targets
NRG1 -> HIF1A Expression Target
NGF -> SMAD3/NF-kB Expression Targets
NGF -> AP-1/TP53/MYC Expression Targets
NGF -> FOXO/MYCN/ELK-SRF Expression Targets
NGF -> CREB/CEBPB/MEF2A Expression Targets
PDGFB -> AP-1/CREB/MYC Expression Target
PDGFC -> CREB Expression Target
PDGFD -> AP-1 Expression Targets
PDGF -> AP-1/CREB/CREBBP/MYC Expression Targets
KIT -> MITF Signaling
PDGFR -> AP-1/MYC Signaling
AVP/Gs -> CREB/ELK/SRF/AP-1/EGR Expression Targets
NTS Expression Targets
AGT -> TP53 Expression Targets
AGT -> CREB Expression Targets
AGT -> ELK/SRF Expression Targets
AVP/Gq -> CREB/ELK/SRF/AP-1/EGR Expression Targets
PRL/GHR -> NF/kB/ELK/SRF/MYC Expression Targets
PDCD1 -> AP-1 Expression Targets
PTPRC -> BCL6 Signaling
GDNF -> HSF1 Signaling
NTRK -> AP-1/CREB/ELK/SRF/MYC/SMAD3/TP53 Signaling
GAS6 -> AP-1/CREB Expression Targets
FIGF -> AP-1 Expression Target
FIGF -> NCOR2 Expression Target
KITLG -> AP-1/CREB/CREBBP/MYC Expression Targets
GDNF -> HSF1 Expression Targets
CSF1 -> AP-1/CREB/CREBBP/MYC Expression Targets
PGF -> AP-1/CREB/CREBBP/MYC Expression Targets
FLT3LG -> AP-1/CREB/CREBBP Expression Targets
Ras-GRF Regulation Signaling
Androgen Receptor non-Genomic Signaling
FOXO1 Signaling
MERTK Signaling
TGF-beta Signaling
AXL Receptor Tyrosine Kinase Signaling
KRAS Signaling
Estrogens/ESR1 non-Genomic Signaling
EGFR Signaling
HRAS Signaling
TCR -> AP-1 Expression Targets
T-Cell Receptor -> AP-1 Signaling
TGFA -> TP53 Expression Targets
TGFA -> HIF1A Expression Targets
TGFA/AP-1/ATF Expression Targets
TGFA -> CREB/CREBBP/ELK-SRF/MYC Expression Targets
LTA Expression Targets
TNF -> AP-1 Expression Targets
TNF -> ELK-SRF Expression Targets
TNF -> CREB Expression Targets
TNF -> TP53/ATF Expression Targets
TNFRSF1A -> AP-1/ATF/TP53 Signaling
TNFRSF1A -> CREB/ELK-SRF Signaling
Thrombopoietin -> SPI1 Expression Targets
Thrombopoietin -> AP-1/CREB/CREBBP/MYC Expression Targets
Thrombopoietin -> SP1 Expression Targets
ROS in Angiotensin Mediated Cardiovascular Remodeling and Hypertrophy
PLAU -> ELK-SRF/AP-1 Expression Targets
VEGFA -> ATF/CREB/ELK-SRF Expression Targets
VEGFA -> NFATC Expression Targets
VEGFC -> ATF Expression Target
VEGFA -> AP-1/CREBBP/MYC Expression Targets
VEGFA -> NCOR2 Expression Target
VEGFR -> NFATC Signaling
VEGFR -> AP-1/CREB/MYC Signaling
VEGFR -> ATF/CREB/ELK-SRF Signaling
New Pathway
1_Inflammation in keratinocytes in the pathology of acne
2_Hyperseborrhea in acne vulgaris
2_Acute phase initiation in atopic dermatitis
2_Interleukin-17 and interleukin-22 signaling in psoriasis
1_The onset of atopic dermatitis
1_TNF and IL1B provoke ECM degradation in osteoarthritis
2_Osteoblast-mediated bone demineralization
3_The role of interstitial fibroblasts in pyelonephritis
1_Local estrogen production stimulates ectopic endometrium proliferation
3_Enhanced angiogenesis in endometriosis
2_The intense proliferation and contractile activity of smooth muscle cells in pulmonary hypertension
1_Th2 cell response in asthma
3_1_Mucus accumulation in asthma
2_2_Eosinophilia and neutrophilia in asthma: eosinophil apoptosis
4_Mucin hyperproduction in goblet and mucous cells in COPD
1_CD4+ T cell and epithelial cell response in celiac disease
2_CD8+ T-cell response and mucosal damage in celiac disease
1_2_Insulin synthesis and secretion: insulin secretion
1_1_Insulin synthesis and secretion: insulin processing and storage
4_1_Insulin resistance: insulin signaling
3_Islet beta-cell destruction in T1D
2_1_General pathways of thyroid hormone signaling
Interleukin-17 and interleukin-22 signaling in psoriasis

Group Proteins Involved in Cowden Syndrome
Genes Associated with Syndromic Epilepsy

MedScan ID 6654

LocusLink ID 6654
20662
313845

Alias mSos1
son of sevenless homolog 1
alternate sos1
SOS1
hSos1
ras guanine exchange factor SOS
OTTHUMP00000128306
rSos
Son of sevenless 1
RIKEN cDNA 4430401P03 gene
hereditary gingival fibromatosis-1
RasGEF SOS
Sos1 Ras guanine exchange factor
son of sevenless (Drosophila) homolog 1
rSos1
OTTHUMP00000204121
gingival fibromatosis, hereditary, 1
hereditary gingival fibromatosis 1
SOS-1
SOS gene
hSos
son of sevenless homolog 1 (Drosophila)
gingival fibromatosis gene
4430401P03Rik
4430401P03
9630010N06
gingival fibromatosis protein
Son of sevenless I
GGF I
Son of sevenless
AI449023
Sos
SOS Ras/Rac guanine nucleotide exchange factor 1
GGF1
hereditary gingival fibromatosis-I
Sos I
hereditary gingival fibromatosis I
son of sevenless homolog
son of sevenless proteins
son of sevenless (Drosophila) homolog I
son of sevenless homolog I
mSos
GINGF
GF1
HGF
NS4
guanine nucleotide exchange factor
guanine nucleotide releasing factor
ras guanine exchange factor
son-of-sevenless 1
SOS protein

GO ID 0003677
0005096
0005088
0005089
0017124
0005085
0046982
0001782
0038128
0038095
0007186
0000165
0007265
0007411
0048514
0003209
0019221
0007173
0061029
0001942
0061384
0008286
0050900
1904693
0035264
0048011
0003344
0043547
0043065
0045742
0051057
0035023
0033081
0042129
2000973
0051056
0060021
0007165
0007296
0005737
0005829
0043025
0000786
0005886
0014069
0008543
0003007
0002260
0046579
0007264
0043234
0005100
0097190
0007596
0045087
0030168
0032321
0032320
0005622
0032318
0005543
0006915
0050790
0008624

KEGG ID hsa:6654
mmu:20662
rno:313845

Organism Homo sapiens {Organism urn:agi-taxid:9606}
Mus musculus {Organism urn:agi-taxid:10090}
Rattus norvegicus {Organism urn:agi-taxid:10116}
Homo sapiens
Mus musculus
Rattus norvegicus

Mouse chromosome position 17 50.67 cM
17 44.0 cM

OMIM ID 182530
135300
610733
163955

Rat chromosome position 6q11

Hugo ID 11187
HGNC:11187

Human chromosome position 2p22.1
2p21
2p22-p21

Swiss-Prot Accession Q07889
G5E9C8
Q07889.1
Q3USK4
Q62245
Q62245.2
D4A3T0
A8K2G3
B4DXG2
Q62244
Q53SF8
Q59GG9
Q8NIA3
Q9UKX9
Q2M4G6
Q9JKM6
Q9QYS7
Q497A5

PIR ID A37488
S25715
S25716

GenBank ID NC_000002
NM_005633
NP_005624
XM_005264515
XP_005264572
XM_011533062
XP_011531364
XM_011533064
XP_011531366
NG_007530
AC019171
AAX93186
AC092672
AAY24202
AF106953
AAF04460
AH011624
AAM22406
CH471053
EAX00350
EAX00351
EAX00352
EAX00353
HI376402
CBX55730
LS482418
SPT35795
AB209140
BAD92377
AK290228
BAF82917
AK301960
BAG63374
AL833457
AV702692
L13857
AAA35913
Q07889
NC_000083
NM_009231
NP_033257
AC161447
AF233591
AAF42937
AH008383
AAF08009
AY902349
AAY21059
CH466537
EDL38526
AK014468
AK047849
AK140310
BAE24327
AK141710
AK163885
CB521016
Z11578
CAA77665
Q62245
NC_005105
NM_001100716
NP_001094186
AC_000074
AABR07062682
AABR07062683
AABR07062684
AAHX01041857
AAHX01041858
AAHX01041859
AAHX01041860
AAHX01041861
AAHX01041862
CH473947
EDM02758
BC100642
AAI00643
XM_011533063
XP_011531365
XM_011533061
XP_011531363
XM_011533065
XP_011531367
XM_011533060
XP_011531362
XM_011533066
XP_011531368
NC_018913
AF441466
AF441467
AF441468
AF441469
AF441470
AF441471
AF441472
AF441473
AF441474
AF441475
AF441476
AF441477
AF441478
AF441479
AF441480
AF441481
AF441482
AF441483
AF441484
AF441485
AMYH02003635
AMYH02003636
AMYH02003637
BC140215
AAI40216
AC_000039
AAHY01135073
AAHY01135074
BC146288
AAI46289
BC148799
AAI48800
AC_000134
ABBA01075022
ABBA01075023
ABBA01075024
ABBA01075025
AABR06041446
AABR06041447
AABR06041448
AABR06041449
AABR06041450
AABR06041451
AABR06041452
NT_022184
NW_927719
NW_001838769
AC_000045
Q53SF8
Q59GG9
Q8NIA3
Q9UKX9
NT_039649
NW_001030622
AF094674
AF094675
AF094676
AF094677
AF094679
Q2M4G6
Q3USK4
Q9JKM6
Q9QYS7
NW_047754
NW_001084845
Q497A5

Swiss-Prot ID SOS1_HUMAN
SOS1_MOUSE
Q3USK4_MOUSE
A8K2G3_HUMAN

Cell Localization Cytoplasm

Ensembl ID ENSG00000115904
ENSP00000384675.2
ENST00000402219.6
ENSP00000378479.2
ENST00000395038.6
ENSMUSG00000024241
ENSMUSP00000067786.5
ENSMUST00000068714.6
ENSRNOG00000007106
ENSRNOP00000009359.6
ENSRNOT00000009359.7
ENSP00000384675
ENST00000402219
ENSP00000378479
ENST00000395038
ENSMUSP00000067786
ENSMUST00000068714
ENSRNOP00000009359
ENSRNOT00000009359

MGI ID MGI:98354
98354

RGD ID 1310949

Unigene ID Hs.709893
Hs.732497
Mm.60975
Mm.360004
Rn.91844
Mm.434583

Homologene ID 4117

IPI ID IPI00020131
IPI00311611
IPI00873613
IPI00767217
IPI00360064