Protein CXCR5

URN urn:agi-llid:643
Total Entities 0
Connectivity 869
Name CXCR5
Description C-X-C motif chemokine receptor 5
Notes This gene encodes a multi-pass membrane protein that belongs to the CXC chemokine receptor family. It is expressed in mature B-cells and Burkitt's lymphoma. This cytokine receptor binds to B-lymphocyte chemoattractant (BLC), and is involved in B-cell migration into B-cell follicles of spleen and Peyer patches. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011]
Primary Cell Localization Plasma membrane
Class Receptor

Pathway CXC Chemokine Receptor Signaling
CD16/CD14 Proinflammatory Monocyte Activation
CD8+ Naive T-cell -> CD4+ Naive T-cell Surface Expression Markers
T-lymphoid precursor cell -> CD8+ Naive T-cell Surface Expression Markers
Thymic Follicular Hyperplasia
Proteins Involved in B-Cell Chronic Lymphocytic Leukemia
B-Cell Chronic Lymphocytic Leukemia
Follicular Lymphoma
Mantle Cell Lymphoma
Proteins Involved in T-Cell Acute Lymphoblastic Leukemia
Proteins Involved in Neuroblastoma
Elevated Receptors -> Expression Targets in Lymph Node
CD Markers -> Expression Targets in Lymphoid System and Blood
Chemokine Receptor Family -> Expression Targets in Lymphoid System
Model of PPARG signaling in psoriasis

MedScan ID 643

LocusLink ID 643
12145
29363

Alias CCR5_HUMAN
CD185
MDR15
chemokine (C-X-C motif) receptor 5
Burkitt lymphoma receptor 1 isoform II
Burkitt lymphoma receptor 1 isoform 2
Burkitt lymphoma receptor 1, GTP binding protein
Burkitt lymphoma receptor 1 isoform 1
Burkitt'S lymphoma receptor I
neurolymphatic receptor
Blr I
C-X-C chemokine receptor type 5
CXCL13 receptor
chemokine receptor CXCR5
chemokine receptors CXCR5
Burkitt lymphoma receptor 1, GTP binding protein (chemokine (C-X-C motif) receptor 5)
antigen CD185
burkitt lymphoma receptor 1 homolog
CXCR5 receptor
CXCR5 receptors
G protein-coupled receptor BLR1
C-X-C chemokine receptor type V
LOC112887
LOC115271
CD185 antigen
MGC117347
CXCL13 receptors
Burkitt lymphoma receptor 1
Monocyte-derived receptor 15
CXC-R5
BLC receptor
C-X-C motif chemokine receptor 5
Blr1
chemochine (C-X-C motif) receptor 5
Burkitt lymphoma receptor I
G protein-coupled receptor BLR I
CCR5_MOUSE
CXCR5
Burkitt'S lymphoma receptor 1
B-lymphocyte chemoattractant receptor
Burkitt lymphoma receptor 1, GTP-binding protein
CXCR-5
MDR-15
Gpcr6
NLR

GO ID 0019957
0016493
0016494
0004930
0019956
0042113
0007186
0019722
0060326
0070098
0006935
0006955
0030595
0048535
0032467
0007204
0009897
0005887
0005886
0007165
0016021
0016020

KEGG ID hsa:643
mmu:12145
rno:29363

Organism Homo sapiens {Organism urn:agi-taxid:9606}
Mus musculus {Organism urn:agi-taxid:10090}
Rattus norvegicus {Organism urn:agi-taxid:10116}

Mouse chromosome position 9 24.84 cM

OMIM ID 601613

Rat chromosome position 8q22

Hugo ID 1060

Human chromosome position 11q23.3

Swiss-Prot Accession A0N0R2
A8K647
P32302
Q2YD84
P32302.1
Q04683
Q04683.2
P34997
G3V7M1
P34997.1
Q14811
Q6P3C2

PIR ID S26667
S42628
S32785

GenBank ID NC_000011
NM_001716
NP_001707
NM_032966
NP_116743
AP004609
CH471065
EAW67415
EAW67416
EF064770
ABK41953
EF444957
ACA05956
JC535580
CEF39387
X83755
CAA58713
AK291512
BAF84201
AW575330
BC110352
AAI10353
CO958128
DA815880
X68149
CAA48252
X68829
CAA48723
P32302
NC_000075
NM_007551
NP_031577
AC125129
CH466522
EDL25602
JC535582
CEF39388
X83756
CAA58714
AK089611
AK133064
BAE21492
AK155954
BAE33519
AK156087
BAE33583
AK157016
BAE33932
BC064059
AAH64059
L20332
AAA16852
X71788
CAA50673
Q04683
NC_005107
XM_006242901
XP_006242963
NM_053303
NP_445755
AC_000076
AAHX01054361
AC105645
CH473975
EDL95327
X71463
CAA50582
P34997

Swiss-Prot ID CXCR5_HUMAN
CXCR5_MOUSE
CXCR5_RAT

Cell Localization Cell membrane

Ensembl ID ENSG00000160683
ENSP00000292174.4
ENST00000292174.4
ENSMUSG00000047880
ENSMUSP00000050444.7
ENSMUST00000062215.7
ENSRNOG00000012430
ENSRNOP00000016580.1
ENSRNOT00000016580.3

MGI ID MGI:103567

RGD ID 62010