Protein ITPR1

URN urn:agi-llid:3708
Total Entities 0
Connectivity 1313
Name ITPR1
Description inositol 1,4,5-trisphosphate receptor, type 1
Notes This gene encodes an intracellular receptor for inositol 1,4,5-trisphosphate. Upon stimulation by inositol 1,4,5-trisphosphate, this receptor mediates calcium release from the endoplasmic reticulum. Mutations in this gene cause spinocerebellar ataxia type 15, a disease associated with an heterogeneous group of cerebellar disorders. Multiple transcript variants have been identified for this gene. [provided by RefSeq, Nov 2009]
Primary Cell Localization Cytoplasm
Class Transporter
ObjectType Protein

Pathway Alzheimer's Disease
Circadian Clock Genes Mutations Cause Insomnia
Skin Aging
High Fat Diet Activates cAMP Related Exocytosis in Synapse and Endocrine Cell
GCG and PPY Regulate Metabolism and Satiety
mTOR Signaling Activation by Taste Sensor Receptors (Rodent Model)
Taste Receptors Activation in Tongue
GUCY2C Signaling in Apetite Regulation
L-cell: GCG, PYY and 5-HT Release
P-cell Activation
I-cell: CCK-8 Secretion and Regulation of Eating Behavior
D-cell: Somatostatin Release
A-cell (X-like): Ghrelin and Nesfatin-1 Synthesis
G-cell: Gastrin Secretion
ECL-cell: CHGA and Histamine Synthesis
Insulin Secretion
Dopamine Receptors Signaling
Serotonin Receptors Signaling
Catecholamines Secretion from Adrenal Gland
Thyroid Hormones Common non-Genomic Effects in Hyperthyroidism
Circadian Clock and Sleep Regulation by Melatonin
Norepinephrine Release Regulation
Dopamine Synthesis and Release
CRH Secretion Regulation
Prolactin Production
Oxytocin Action in Mammary Gland
Thrombopoietin Receptors Signaling in Platelet Maturation
Mineralcorticoids Secretion Regulation
Dectin-1 (CLEC7A) Signaling
Dectin-2 (CLEC6A)/Mincle (CLEC4E)/BDCA2 (CLEC4C) Signaling
T-Cell Dependent B-Cell Activation
T-Cell Independent B-Cell Activation
V(D)J Recombination Activation
Natural Killer Cell Activation through C-Type Lectin-like Receptors
Natural Killer Cell Activation through ITAM-Containing Receptors
Natural Killer Cell Activation through ITSM-Containing Receptors
T-Cell Maturation (Hypothesis)
Natural Killer Cell Activation
T-Cell Central Tolerance
CD8+ T-Cell Activation
Th1-Cell Differentiation
Treg-Cell Differentiation
Th2-Cell Differentiation
T-Cell Receptor Signaling
CXC Chemokine Receptor Signaling
CC Chemokine Receptor Signaling
Platelet Activation via Adhesion Molecules
Scavenger Receptors in Platelet Activation
Scavenger Receptors in Platelet Aggregation
Proplatelet Maturation
Bradykinin Effects in Inflammation
Platelet Activation via GPCR Signaling
Lipoxin A4/FPR2-Related Neutrophil Depression
Annexins in Inflammation Resolution
Eat me Signal: Apoptotic Cell Induces Phagocytosis
Leukotriene Effect on Vascular Endothelial Cell Response
Eicosanoids in Myeloid Cell Activation
Leukotriene Effect on Airway Smooth Muscle Response
Histamine Receptor H3 Signaling in Neurons
Prostaglandin E2 and Histamine in Gastric Acid Secretion
Basophil Activation
Eosinophil Activation
Mast-Cell Activation via IgE Signaling
Mast-Cells De Novo Synthesized Mediators via IgE Independent Signaling
CD16/CD14 Proinflammatory Monocyte Activation
Macrophage M2-Related Phagocytosis
anti-Inflammatory Function of Macrophage M2 Lineage
Neutrophil Recruitment and Priming
Neutrophil Activation via FCGR3B
Neutrophil Degranulation via FPR1 Signaling
CR3 Mediated Phagocytosis in Neutrophils and Macrophages
Neutrophil Chemotaxis
Neutrophil Activation via Adherence on Endothelial Cells
SNS Related Adrenal Cortex Response
Vascular Smooth Muscle Cell/Pericyte Migration and Proliferation
Vascular Endothelial Cell Activation by Cytokines
Vascular Endothelial Cell Activation by Blood Coagulation Factors
Vascular Endothelial Cell Permeability Activation
Potassium Flux Regulation
GFs/TNF -> Ion Channels
Nociception Expression Targets Signaling
Vascular Motility
Ca2+ Flux Regulation
TAAR1 -> Neurotransmitter Uptake
NPY1R -> CRH/POMC Production
NTSR1 Expression Targets
CRH -> Synthesis of Corticosteroids
EDNRA/B -> Vascular Motility
CCKBR -> Neurotransmitter Uptake
ADORA3 -> Mast-Cell Degranulation
ADRA1 -> Vasoconstriction
ADRA1A -> IL6 Production
ADRA1 -> Ion Channels
ADRA2C/ADRB2 -> Vasoconstriction
ADRA2C/ADRB2 -> Synaptic Endocytosis
ADRA1 -> Prostaglandin Generation
BDKRB1/2 -> Ion Channels
BDKRB1/2 -> Prostaglandin Generation
CNR1/2 -> Membrane Transport
CNR1/2 -> Vascular Motility
CNR1/2 -> IL1B/2/4/6/10 Production
DRD2 Expression Targets
GALR1/2/3 -> POMC/NPY Production
GALR1/2/3 -> Neurotransmitter Metabolism
HRH1/2 -> Membrane Polarization
HRH1/3 -> Synaptic Transmission
HRH1/2 -> Vascular Motility
HRH2/4 -> IL6/10 Production
CHRM1 -> IL2 Production
CHRM1/2/3/5 -> Ion Channels
CHRM1/2/3 -> Vascular Motility
OPRK -> Pain Perception
PTGFR -> Vasoconstriction
PTGIR -> IL6 Production
PTGER1/4 -> Vascular Motility
PTGER2/3 -> Vascular Motility
PTGER2/3 -> Inflammation-Related Expression Targets
HTR1 -> IL6 Production
HTR5 -> TNF Production
HTR2 -> Membrane Transport
HTR1 -> Membrane Transport
HTR1 -> Vascular Motility
TACR1 -> Membrane Transport
TACR1 -> TNF/IL6/IL8 Production
GRM1/5 (Postsynaptic) -> Ion Channels
P2RY11/13/14 -> IL8/10 Production
P2RY1/2/4/6 -> Potassium Channels
NTRK1/2/3 -> Acetylcholine Production
EPHB -> NMDA Receptor Activation
Luteinizing Hormone in Oocyte Meiotic Resumption
Agomelatine Antidepressant Action
Histamine in Arousal Regulation
Circadian Clock in Sleep Regulation
Endocannabinoids Role in Sleep Regulation
Circadian Clock Genes in Suprachiasmatic Nuclei Neurons
Hypocretin (Orexin) in Arousal Regulation
Adenosine Role in Sleep Regulation
Retinal Ganglion and Suprachiasmatic Nucleus in Melatonin Synthesis Regulation
G0/G1 Phase Transition
Gap Junction Assembly
TRRAP/TIP60 in Chromatin Remodeling
Th1-Cells Activation and Proliferation in Atherosclerosis
Proteins Involved in Arterial Hypertension
Endothelin Signaling in Arterial Hypertension
Arterial Hypertension
Aldosterone Synthesis Acute Regulation
Endothelial Cell Dysfunction in Arterial Hypertension
Aldosterone Synthesis Chronic Regulation
Smooth Muscle Cell Dysfunction in Arterial Hypertension
TRPM4/6/7/8 Signaling in Arterial Hypertension (Hypothesis)
Smooth Muscle Cell Dysfunction in Pulmonary Hypertension
Myocardial Remodeling
Vascular Reactivity in Raynaud Disease
Cold Stress and Adrenoceptor alpha 2C Signaling in Raynaud Disease
NO Synthesis in Early Vasospasm
Contraction Due Vasospasm
Atopic Dermatitis Onset
Mast-Cells Activation in Atopic Dermatitis
Cell Cycle Dysregulation in Melanoma
WNT Signaling in Melanoma
Melanoma
Apoptosis Block in Melanoma Cell
MITF as a Regulator of Melanoma Cell Development
Th0-Cell Aberrant Activation in Systemic Lupus Erythematosus
Th1-Cell Function in Systemic Lupus Erythematosus
B-Cell Activation in Systemic Lupus Erythematosus
Th2-Cell Function in Systemic Lupus Erythematosus
Acute Cytotoxic CD8+T-Cell Response against Melanocytes
Vitiligo
T-Cell Cytotoxic Response against Melanocytes in Vitiligo
Apoptosis of Melanocyte in Vitiligo
Humoral Immunity in Vitiligo
CD8+ T-Cell Response to Self-Determinants in Diabetes
Treg-Cell Function in Diabetes Mellitus Type 1
Natural Killer T-Cell Roles in Diabetes Mellitus Type 1
non-Suppressive Treg-Cell in Diabetes Mellitus Type 1
TLR2 Signaling in Treg-Cell in Type 1 Diabetes (Animal Model)
Natural Killer Cell in Diabetes Mellitus Type 1
Peripheral Tolerance to Autoantigens Recession in Diabetes Mellitus Type 1
Treg-Cell Activation in Diabetes Mellitus
Proliferative Diabetic Retinopathy
G-Proteins Signaling in Insulin Secretion in beta-Cell
Olanzapine Effect on Insulin Secretion in Diabetes Mellitus
Bone Remodeling in Hyperthyroidism
Cardiovascular Effects in Hyperthyroidism
Thyroid Dysfunction
Immune System Activation in Hyperthyroidism
GNRH Release Impairment in Hypogonadotrophic Hypogonadism
GNRH Signaling Impairment in Hypogonadotrophic Hypogonadism
KISS1 Production Impairment in Hypogonadotropic hypogonadism
Hypothyroidism, Secondary (Central)
Thyroid Stimulating Hormone (TSH) Resistance in Congenital Hypothyroidism
Overt Hypothyroidism, Primary
Thyroid Stimulating Hormone (TSH) Secretion in Overt Hypothyroidism
Central Hypothyroidism
Tertiary Hypothyroidism
Prolactinoma Overiew
CD4+T-Cell Response in Celiac Disease
CD8+ T-Cell Response in Celiac Disease
Metastatic Colorectal Cancer
B-Cell Activation in Crohn's Disease
OipA Signaling in Helicobacter Pylori Infection
CagA Phosphorylation Dependent Signaling
EDN, NRG, NRTN, and GDNF/RET Signaling in Hirschsprung Disease
Th2-Cell Function in Ulcerative Colitis
T-Cell Cytotoxic Response in Ulcerative Colitis
Antiphospholipid Antibodies in Platelets and Coagulation Cascade
B-Cell Chronic Lymphocytic Leukemia
Diffuse Large-B-Cell Lymphoma
Diffuse Large-B-Cell Lymphoma ABC Subtype
Hodgkin Lymphoma
Mantle Cell Lymphoma
mTOR/NF-kB/BCR Signaling Disregulation in Mantle Cell Lymphoma
Mucosa-Associated Lymphoid Tissue (MALT) Lymphoma
Splenic Marginal Zone Lymphoma
Platelet and Coagulation Cascade Activation by Antiphospholipid Antibodies
T-Cell Acute Lymphoblastic Leukemia
TRPM7/8 in Pancreatic Adenocarcinoma
Eosinophil Survival in Asthma
Eosinophil Activation and Degranulation in Asthma
Airway Smooth Muscle Cell High Rate Proliferation
IgE Induces Airway Smooth Muscle Cell Proliferation
Airway Smooth Muscle Cell Contraction
Goblet-Cell Exocytosis in Asthma
Neutrophil Degranulation via FPR1/IL8
Basophil Activation in Asthma
Mast-Cell Activation in Asthma
Mast-Cell Related Chemokines Signaling in Asthma
Antigen-Presenting Cell Role in Asthma
Th2-Cell Response in Asthma
CFTR Facilitates Oxidative Stress in Airway Epithelium in CF
Airway Epithelial Cell Dysfunction
CFTR Expression in Epithelial Cells (Class I Mutations)
CFTR Related Ion-Channel Dysfunction in Cystic Fibrosis Airway Epithelium (Class III Mutations)
Steroidogenesis Impairement in Polycystic Ovary Syndrome
Ovulation Block
Polycystic Ovary Syndrome
FSH Action in Polycystic Ovary Syndrome
PTPN22 Role in Rheumatoid Arthritis
B-Cells Function in Systemic Scleroderma
Th2-Cells Function in Systemic Scleroderma
WHIM Syndrome
Dentin Formation Disruption
CD8+ T-Cell Action Impairment in HIV Type 1 Infection
CD4+ T-Cell Function Decline in HIV
Acinar Cells in the Saliva Formation
Epithelial Cell in the Saliva Formation
Proteins Involved in Friedreich Ataxia
Glutamate Toxiicity Effects on Striatum Medium Spiny Neurons in Hantington's Disease
ER Stress in Huntington Disease
Proteins Involved in Huntington Disease
Ca2+ Toxicity in Neurons
BDNF Upregulation Triggered by Seizures
Blood-Brain Barrier Disruption in Epileptiform Disorders
mTOR Hyperactivation after Status Epilepticus
Glutamate, D-Serine, and ATP Release from Astrocytes
Glioblastoma, Primary
Glioblastoma, Secondary
Astrocytoma
Vascular Endothelial Cell Vasodilation in Brain
CCL2 Role in CGRP Expression and Release
Dopamine Synthesis and Release in Migraine
Vascular Smooth Muscle Cell Vasodilation in Brain
Postsynaptic Neuron Activation
eNOS (NOS3) Activation via Prostaglandin E2 and Histamine
NO Effect on Vasodilation and Vasoconstriction
GABRB3 Mutation and Adenosine Deaminase Polymorphism
Hypocretin Elevation and Monoamine Oxidase Decrease/Inhibition
Angiogenesis in Endometriosis
Coagulation Factors and PAR1/2 Receptors (F2R/F2RL1) in Endometriosis
EGFR and PTAFR Signaling in Ovarian Cancer
HPV E5 Regulates EDNRA and EGFR Signaling Pathway in Keratinocytes
Prostate Cancer
TRPM8 Effects in Prostate Cancer (Hypothesis)
Oxidative Stress, All-Trans-Retinal and Lipofuscin Toxicity in AMD
Ca2+ Toxicity in Lens Cells
VEGFA in Neovascular Glaucoma
Glutamate Mediated Excitotoxicity in Glaucoma
PGF2-alpha Effect on Treatment
Serotonin Signaling in the Ciliary Body
Cytokines Trigger Otitis Media
Alveolar Macrophages Dysfunction in COPD
Muscarinic Receptor-Mediated Airway Smooth Muscle Contraction
Alveolar Epithelial Cell Dysfunction in COPD
Penile Detumescense Augmentation Mechanisms
Endothelial Cell Dysfunction in Glomerulonephritis
Sertoli Cells Dysfunction Causes Male Infertility
CD38/CD3 -> JUN/FOS/NF-kB Signaling in T-cell Proliferation
CD38/CD19 -> JUN/FOS/NF-kB Signaling in B-cell Proliferation
CD38 -> cADPR/Calcium Signaling
CD157 -> cADPR/Calcium Signaling
ANGPT1 -> CREB/CREBBP Expression Targets
ANGPT2 -> AP-1/CREBBP/MYC Expression Targets
AREG -> NFATC Expression Target
AREG -> CREB/CREBBP Expression Targets
AREG -> NCOR2 Expression Targets
AREG -> SMAD1 Expression Target
AREG -> HIF1A Expression Targets
AREG -> AP-1 Expression Targets
Noradrenaline/Gs Expression Targets
Noreadrenaline/Gq Expression Targets
Epinephrine/Gs Expression Targets
Acetylcholine Expression Targets
Serotonin/Gq Expression Targets
Epinephrine/Gq Expression Targets
Dopamine/Gi Expression Targets
B-Cell Receptor -> NFATC Signaling
B-Cell Receptor -> AP-1 Signaling
B-Cell Receptor -> NF-kB Signaling
BTC -> NFATC Expression Targets
BTC -> AP-1/ATF/CREB Expression Targets
BTC -> EP300/ETS/ETV/SP1 Expression Targets
SELE -> ELK-SRF Signaling
CD2 Expression Targets
CD19 Expression Targets
CD81 -> AP-1 Expression Targets
CD247 Expression Targets
gamma Globulins Expression Targets
FCGR3A Expression Targets
CD19/CR2 Expression Targets
CD8 -> AP-1 Expression Targets
CD72 -> CREB/CREBBP Expression Targets
CD72 -> NF-kB Expression Targets
CD8 -> ATF/CREB/CREBBP Expression Targets
CD8 -> NF-kB Expression Targets
CD80 -> AP-1 Expression Targets
CD81 Expression Targets
CD80 -> NF-kB Expression Targets
CD80 -> NFATC Expression Targets
CD86 -> NFATC Expression Targets
CD86-> NFATC Expression Targets
CD86 -> NF-kB Expression Targets
CXCL6 Expression Targets
CXCL1 Expression Targets
CXCL2 Expression Targets
CXCL3 Expression Targets
CXCL5 Expression Targets
Complement Component GPCRs Signaling
Clozapine Induced Granulocytopenia
EGF -> HIF1A Expression Targets
EGF -> AP-1/ATF Expression Targets
EGF -> CREB/CREBBP/ELK/SRF/MYC Expression Targets
EGF -> MEF/MYOD/NFATC Expression Targets
EGF -> TP53 Expression Targets
EGF -> NCOR2 Expression Target
EGFR -> NCOR2 Signaling
EGFR/ERBB3 -> MEF/MYOD/NFATC/MYOG Signaling
EGFR/ERBB2 -> TP53 Signaling
ERBB2/3 -> EP300/ETS/ETV/SP1 Signaling
EGFR -> SMAD1 Signaling
EGFR/ERBB2 -> HIF1A Signaling
EGFR -> AP-1/ATF2 Signaling
EGFR -> AP-1/CREB/ELK/SRF/MYC Signaling
EREG -> CREB Expression Target
EREG -> EP300/SP1 Expression Targets
EREG -> HIF1A Expression Target
EREG -> AP-1/ATF Expression Targets
Erythropoietin -> AP-1/MYC/CREB Expression Targets
Erythropoietin -> ELK/SRF Expression Targets
F2 -> AP-1/CREB/ELK/SRF/SP1 Expression Targets
PLG -> AP-1/CREB/ELK/SRF/SP1 Expression Targets
FGF9 -> AP-1/CREB/MYC Expression Targets
FGF10 -> AP-1/CREB/CREBBP/MYC Expression Targets
FGF1 -> AP-1/CREB/ELK/SRF/MYC Expression Targets
FGF1 -> NCOR2 Expression Target
FGF7 -> RUNX Expression Targets
FGF8 -> AP-1/CREB/MYC Expression Targets
FGF1 -> RUNX Expression Targets
FGF18 -> AP-1/CREB Expression Targets
FGF23 -> NCOR2 Expression Targets
FGF8 -> RUNX Expression Targets
FGF9 -> RUNX Expression Targets
FGF2 -> NCOR2 Expression Targets
FGF4 -> AP-1/MYC Expression Targets
FGF7 -> AP-1/CREB/CREBBP/MYC Expression Targets
FGF2 -> RUNX Expression Targets
FGF2 -> AP-1/CREB/CREBBP/ELK/SRF/MYC Expression Targets
FGFR -> RUNX2 Signaling
FGFR -> AP-1/CREB/CREBBP/ELK/SRF/MYC Signaling
FPR1 -> Cytoskeleton Signaling
ADCYAP1 Expression Targets
FSHR Expression Targets
Glutamate/Gq Expression Targets
VIP Expression Targets
HBEGF -> AP-1/ATF Expression Targets
HBEGF -> TP53 Expression Targets
HBEGF -> EP300/ETS/ETV/SP1 Expression Targets
HBEGF -> HIF1A Expression Targets
HBEGF -> MEF/MYOD Expression Target
HBEGF -> CREB/MYC Expression Targets
HGF -> AP-1/CREB/ELK/SRF/MYC Expression Targets
HGFR -> AP-1/CREB/MYC Signaling
EGFR Transactivation in Cancer and Non-Cancer Cells
TAM Receptor Signaling Activation in Cancer
G0/G1 Cell Cycle Phase Transition Activation in Cancer
NFKB Canonical Signaling Activation in Cancer
VEGF Independent Angiogenesis in Cancer
CDH2 Activation Promotes Cancer Cell Migration and Survival
Treg Cells Promote Immunosuppression in Cancer Immune Escape
CD2 -> NFATC1 Signaling
CD19 -> JUN/ELK Signaling
FcIgER -> NFATC1 Signaling
FcIgER -> ELK-SRF Signaling
ICAM1 -> AP-1/CREB/ELK/SRF Signaling
FibronectinR -> AP-1/ELK/SRF/SREBF Signaling
CTGF -> AP-1/CREB/MYC Expression Targets
CTGF -> NCOR2 Expression Target
ICAM1 Expression Targets
IL16 -> AP-1 Expression Targets
IL16-> ATF/CREB/CREBBP Expression Target
UrokinaseR -> ELK/SRF Signaling
PTPRC -> BCL6 Expression Targets
Prostaglandin F Expression Targets
Thromboxane A2 Expression Targets
LPA Expression Targets
PAF/Gq -> AP-1/ATF1/CREB/ERK/SRF Expression Targets
Dronabinol/Anandamide Expression Targets
Morphine Expression Targets
PAF/Gq -> NF-kB Expression Targets
S1P Expression Targets
PGE1 Expression Targets
NRG1 -> MEF/MYOD Expression Targets
NRG1 -> EP300/ETS/ETV/SP1 Expression Targets
NRG1 -> CREB/CREBBP/ELK/SRF/MYC Expression Targets
NRG1 -> TP53 Expression Target
NRG1 -> AP-1/ATF Expression Targets
NRG1 -> HIF1A Expression Target
NGF -> SMAD3/NF-kB Expression Targets
NGF -> AP-1/TP53/MYC Expression Targets
NGF -> FOXO/MYCN/ELK-SRF Expression Targets
BDNF Expression Targets
NTF3 Expression Targets
NTF4 Expression Targets
NGF -> CREB/CEBPB/MEF2A Expression Targets
Adenosine Expression Targets
PDGFB -> AP-1/CREB/MYC Expression Target
PDGFC -> CREB Expression Target
PDGFD -> AP-1 Expression Targets
PDGF -> AP-1/CREB/CREBBP/MYC Expression Targets
KIT -> MITF Signaling
PDGFR -> AP-1/MYC Signaling
AVP/Gs -> CREB/ELK/SRF/AP-1/EGR Expression Targets
GNRH1 Expression Targets
NTS Expression Targets
GAST Expression Targets in GAST Expression Targets
AGT -> TP53 Expression Targets
GNRH2 Expression Targets
OXT Expression Targets
POMC Expression Targets
CCL11 Expression Targets
EDN1 Expression Targets
AGT -> CREB Expression Targets
AVP/Gs -> MEF/MYOD/NFATC/MYOG Expression Targets
NPY Expression Targets
AVP/Gq -> STAT Expression Targets
IFNA1/Gq Expression Targets
AGT -> ELK/SRF Expression Targets
TAC1 Expression Targets
AVP/Gq -> MEF/MYOD/NFATC/MYOG Expression Targets
EDN3 Expression Targets
AVP/Gq -> CREB/ELK/SRF/AP-1/EGR Expression Targets
PDCD1 -> ATF/CREB/CREBBP Expression Targets
PDCD1 -> NFATC Expression Targets
PDCD1 -> AP-1 Expression Targets
PTPRC -> BCL6 Signaling
AngiopoietinR -> AP-1 Signaling
GDNF -> HSF1 Signaling
NTRK -> AP-1/CREB/ELK/SRF/MYC/SMAD3/TP53 Signaling
GAS6 -> AP-1/CREB Expression Targets
FIGF -> AP-1 Expression Target
FIGF -> NCOR2 Expression Target
KITLG -> AP-1/CREB/CREBBP/MYC Expression Targets
GDNF -> HSF1 Expression Targets
CSF1 -> AP-1/CREB/CREBBP/MYC Expression Targets
PGF -> AP-1/CREB/CREBBP/MYC Expression Targets
FLT3LG -> AP-1/CREB/CREBBP Expression Targets
WNT/Calcium non-Canonical Signaling
Lysophosphatidic Acid/LPARs Signaling
Ras-GRF Regulation Signaling
MERTK Signaling
Ras Signaling
AXL Receptor Tyrosine Kinase Signaling
VEGF Signaling
Estrogens/ESR1 non-Genomic Signaling
EGFR Signaling
NF-kB Canonical Signaling
ERK/MAPK Canonical Signaling
TCR -> CREB/CREBBP/ATF Expression Targets
TCR -> NF-kB Expression Targets
TCR -> NFAT Expression Targets
TCR -> AP-1 Expression Targets
T-Cell Receptor -> NF-kB Signaling
T-Cell Receptor -> NFATC Signaling
T-Cell Receptor -> CREBBP Signaling
TGFA -> TP53 Expression Targets
TGFA -> HIF1A Expression Targets
TGFA -> MEF/MYOD/NFATC Expression Targets
TGFA/AP-1/ATF Expression Targets
TGFA -> CREB/CREBBP/ELK-SRF/MYC Expression Targets
Thrombopoietin -> AP-1/CREB/CREBBP/MYC Expression Targets
IL1B -> PGE2 Expression Targets
Elevated Receptors -> Expression Targets in Kidney
PLAU -> ELK-SRF/AP-1 Expression Targets
VEGFA -> ATF/CREB/ELK-SRF Expression Targets
VEGFA -> NFATC Expression Targets
VEGFC -> ATF Expression Target
VEGFA -> AP-1/CREBBP/MYC Expression Targets
VEGFA -> NCOR2 Expression Target
VEGFR -> NFATC Signaling
VEGFR -> AP-1/CREB/MYC Signaling
VEGFR -> ATF/CREB/ELK-SRF Signaling
ace2
cypa
Model of PPARG signaling in psoriasis
New Pathway
2_Acute phase initiation in atopic dermatitis
1_The onset of atopic dermatitis
2_Podocyte dysfunction in glomerulonephritis
3_Enhanced angiogenesis in endometriosis
1_Disruption of luteinizing hormone and follicle-stimulating hormone secretion in PCOS
2_Oxidative stress, all-trans-retinal, and lipofuscin toxicity in agerelated macular degeneration
2_Pathogens stimulate mucins expression in the middle ear
2_Oxidized LDL causes endothelial dysfunction in atherosclerosis
3_Dysfunction of smooth muscle cells in hypertension
4_Endothelial cells repress vasoconstriction in hypertension
1_Rise in aldosterone synthesis in adrenal zona glomerulosa cells
2_The intense proliferation and contractile activity of smooth muscle cells in pulmonary hypertension
1_Cigarette smoke causes dysfunction and production of inflammatory mediators in alveolar epithelial cells
3_1_Mucus accumulation in asthma
2_1_Eosinophilia and neutrophilia in asthma: eosinophil migration and activation
2_2_Eosinophilia and neutrophilia in asthma: eosinophil apoptosis
4_1_Airway smooth muscle cells contraction
4_2_Airway smooth muscle cells proliferation and airway tissue remodeling
4_Mucin hyperproduction in goblet and mucous cells in COPD
1_CD4+ T cell and epithelial cell response in celiac disease
2_CD8+ T-cell response and mucosal damage in celiac disease
1_2_Insulin synthesis and secretion: insulin secretion
1_1_Insulin synthesis and secretion: insulin processing and storage
1_CFTR expression and degradation in epithelial cells in cystic fibrosis (class I-II mutations)
3_Islet beta-cell destruction in T1D
3_Pain perception in diabetic neuropathy
2_Neuron and Schwann cell death
1_1_Glutamate overload enforced prostaglandins and NO synthesis in neurons
1_2_Glutamate overload and NO-mediated vasodilation
1_Decreased secretion of thyroid hormones
2_1_General pathways of thyroid hormone signaling

Source curated
GO component

MedScan ID 3708
622741

LocusLink ID 3708
16438
25262
100038404
18544
317697
567611
57043
140449

Alias Purkinje cell protein 1
OTTHUMP00000209578
Ins(1,4,5)P3 receptor I
IP3R I
D6Pas2
ITPR1
OTTHUMP00000207085
SCA29 locus
SCA16 protein
spinocerebellar ataxia 16 protein
Pcp1
SCA29 gene
opisthotonus gene
SCA16 locus
protein PCD-6
Gm10429
InsP3R1
DKFZp313E1334
Purkinje cell protein I
SCA16 gene
SCA16 region
Inositol 1,4,5-trisphosphate receptor 1
inositol 1,4,5-triphosphate receptor I
Inositol 1,4,5-trisphosphate receptor I
SCA29 region
InsP3R
type 1 InsP3 receptor
SCA29 protein
InsP3R I
SCA15 gene
PPP1R94
inositol 1,4,5-trisphosphate-binding protein P400
ENSMUSG00000072853
SCA15 locus
spinocerebellar ataxia-16 protein
Pcp I
ITPR I
IP3R1
protein phosphatase 1, regulatory subunit 94
SCA15 region
spinocerebellar ataxia-29 gene
inositol 145-triphosphate receptor I
InsP>3<R type I
spinocerebellar ataxia 15 protein
DKFZp313N1434
type 1 inositol 1,4,5-trisphosphate receptor
inositol 145-triphosphate receptor 1
spinocerebellar ataxia 29 protein
SCA15 protein
inositol 1,4,5-triphosphate receptor 1
spinocerebellar ataxia-29 protein
spinocerebellar ataxia 29 gene
spinocerebellar ataxia-15 protein
Ins(1,4,5)P3 receptor 1
I145TR
ACV
CLA4
IP3R
SCA15
SCA16
SCA29
IP3 receptor
IP3R 1
inositol 1,4,5-triphosphate receptor, type 1
inositol 1,4,5-trisphosphate receptor type 1
opt
P400
wblo
Pcp-1
Itpr-1
opisthotonus
IP-3-R
spinocerebellar ataxia 15
Spinocerebellar ataxia 29
spinocerebellar ataxia 16
inositol 1,4,5-trisphosphate receptor, type 1
InsP3R type I
inositol 145-triphosphate receptor type 1
inositol 1,4,5-triphosphate receptor type 1
inositol 145-triphosphate receptor type I
inositol 1,4,5-triphosphate receptor, type
InsP>3<R type 1
Inositol 1,4,5-trisphosphate receptor type I

GO ID 0019855
0005509
0015085
0015278
0070679
0098695
0005220
0035091
0006816
0032469
0042045
0048016
0070059
0050849
0030168
0009791
0010506
1903779
0050796
0099566
0051209
0001666
0007165
0050882
0098685
0005955
0030659
0005783
0005789
0016021
0016020
0005637
0005730
0048471
0005886
0031088
0031094
0031095
0014069
0016529
0030667
0030658
0005262
0005216
0008022
0019903
0044877
0006915
0070588
0071320
0006811
0097421
1901215
0043065
0051928
0007204
2000347
0010976
0051289
0055085
0098982
0005737
0031410
0030425
0030176
0043231
0045121
0043025
0005635
0098794
0098793
0032991
0030868
0097060
0071456
0016358
0032403
0006810
0005829
0043234
0005218
0038095
0038096
0007202
0007596
0006112
0007173
0008543
0045087
0048011
0044281
0048010
0005623
0005622
0008219
0008095
0004872
0034220
0005792
0005515
0005887
0006812
0005261

KEGG ID hsa:3708
mmu:16438
rno:25262

MedLine Reference 11316737
11587548
11972451
12143036
12167631
12435588
12477932
12623131
12820984
1338970
14517800
14982933
15060019
15364918
15739177
15774532
15843050
15911880
16118475
16223514
16237118
16377004
16691292
16723353
16840702
1849282
2165071
8567977
9073177
10051594
10095099
10098882
10349636
10426189
10482245
10505685
10609087
10811729
10922068
11040263
11042159
11076861
11172053
11217851
11334652
11368972
11476286
11696558
11700294
11860456
11955285
11980893
12110570
12118121
12421829
12442173
12444087
12466851
12611586
12621039
12654335
12828938
12967979
12972155
1374893
14506248
14687547
14706453
14722080
14741211
15016804
15026142
15184066
15201137
15284241
15583010
15590059
15652484
15664189
15890645
16014380
16091359
16141072
16141073
16286649
16458354
1648733
16606357
1662017
16675011
1672287
16731645
16783635
16793548
16844763
16925983
16964447
17038520
17050730
2554142
2707487
2762133
3141586
3199205
7642703
7755592
7852357
7896292
7945203
7946968
8081710
8530061
8538767
8641130
8661054
8758947
8780003
8863127
8900188
8930970
8987786
9124414
9231705
9302515
9615221
9697703
9808793
9858485
9867846
9867847
9986730
10209024
10724174
10843712
10874040
11163362
11524429
11574661
11782428
12032348
12196544
12356940
12480535
12525476
12529267
12606542
12676536
12717445
12754204
12766172
14570872
14635192
14685260
14697242
14707143
14761954
15067324
15104175
15613488
15623527
16223735
16621795
17130290
7500840
7559486
8132516
8132598
8521476
8648241
8713116
9346894
9511764
9607712
9808459
9853757
11584008
12714606
2174422
10737800
15146197
16344560
17081983
17256008
17437169
17590087
11544199
15489334
16527252
17208939
17327232
17416589
17482902
17511035
9651219
10506212
12873381
16103111
17284437
17496801
17636122
11445634
17030759
11723290
14981189

Organism Homo sapiens {Organism urn:agi-taxid:9606}
Mus musculus {Organism urn:agi-taxid:10090}
Rattus norvegicus {Organism urn:agi-taxid:10116}
Homo sapiens
Mus musculus
Rattus norvegicus
Bos taurus
Danio rerio

Mouse chromosome position 6 49.74 cM
6 48.0 cM

OMIM ID 147265
206700
606658
117360
606364

Rat chromosome position 4q41

Hugo ID 6180
HGNC:6180
10554
13439

Human chromosome position 3p26.1
3p26-p25

Swiss-Prot Accession B4DER3
Q14643
Q59H91
B4DGH1
Q14643.3
P11881
Q3UVA1
Q8BQN0
Q8C7X9
Q8C8N0
P11881.2
C7E1V2
Q5BJS8
F1LQX8
A0A0A0MY31
P29994
P29994.2
E7EPX7
E9PDE9
Q14660
Q99897
P20943
Q99LG5
Q62869
Q6NV80
ITPR1_HUMAN
ITPR1_RAT
Q8BQN0_MOUSE

PIR ID A55713
S54974
S04844
A36579
B36579

GenBank ID NC_000003
NM_001099952
NP_001093422
NM_001168272
NP_001161744
NM_002222
NP_002213
XM_011533681
XP_011531983
XM_011533683
XP_011531985
XM_011533685
XP_011531987
XM_011533686
XP_011531988
XM_006713131
XP_006713194
XM_005265109
XP_005265166
XM_005265110
XP_005265167
XM_011533684
XP_011531986
XM_011533687
XP_011531989
XM_011533688
XP_011531990
XM_011533690
XP_011531992
XM_017006357
XP_016861846
XM_011533691
XP_011531993
XM_011533692
XP_011531994
XM_017006358
XP_016861847
XM_011533682
XP_011531984
NG_016144
AC018816
AC024168
AC069248
AC090944
AF009963
AL832689
AL832701
CH471055
EAW63908
EAW63909
EAW63910
EAW63911
EAW63912
EAW63913
EAW63914
EAW63915
KF457534
KF457537
KF457539
KF457541
KF457546
KF495812
L47220
AB208868
BAD92105
AI470158
AK293752
BAG57174
AK294594
BAG57782
AK296235
BAG58955
AK309981
AK311008
AW501800
BC144563
AAI44564
BG202086
BM695661
BQ006717
CN431631
CV355426
D26070
BAA05065
DA060305
DB260851
DB544988
DB576768
L38019
AAB04947
S82269
AAD14386
U23850
Q14643
NC_000072
XM_006505631
XP_006505694
XM_006505623
XP_006505686
XM_017321407
XP_017176896
XM_006505627
XP_006505690
XM_006505624
XP_006505687
XM_006505625
XP_006505688
XM_006505632
XP_006505695
XM_006505628
XP_006505691
XM_006505629
XP_006505692
XM_006505633
XP_006505696
XM_017321408
XP_017176897
XM_006505636
XP_006505699
XM_006505626
XP_006505689
XM_017321409
XP_017176898
XM_006505630
XP_006505693
XM_017321410
XP_017176899
XM_006505637
XP_006505700
NM_010585
NP_034715
AC120411
AC153986
AC156506
AH001976
AAA39316
AAA39317
AY857958
CH466523
EDK99408
EDK99409
D78171
AK042240
AK044776
BAC32085
AK047719
BAC33138
AK049015
BAC33514
AK083514
AK087694
AK137477
BAE23370
BC003271
AAH03271
BC068269
AAH68269
BQ180028
BU705754
BX633137
BY145967
CB521690
CF168791
CF539692
CF744794
CJ236273
CK636937
CN459019
CN692248
DN176734
DV652411
M21530
AAA88319
S75867
X15373
CAA33433
P11881
NC_005103
XM_006236987
XP_006237049
NM_001007235
NP_001007236
NM_001270597
NP_001257526
NM_001270596
NP_001257525
XM_008763167
XP_008761389
XM_008763168
XP_008761390
XM_008763171
XP_008761393
XM_008763172
XP_008761394
XM_008763174
XP_008761396
XM_008763176
XP_008761398
XM_008763169
XP_008761391
XM_008763170
XP_008761392
XM_008763173
XP_008761395
XM_008763177
XP_008761399
XM_008763175
XP_008761397
XM_008763178
XP_008761400
AC_000072
AABR07061705
AABR07061706
AABR07061707
AAHX01032183
AAHX01032184
AAHX01032185
AAHX01032186
AAHX01032187
AAHX01032188
CH473957
EDL91478
BC091346
AAH91346
BF402715
FQ225812
FQ233552
GQ233032
ACT21453
J05510
AAA41357
AAA41358
M64698
AAA41448
M64699
AAA41447
U38653
AAC53099
U38665
AAB51330
U38812
AAC53100
P29994
XM_011533689
XP_011531991
NC_018914
AMYH02006182
AMYH02006183
AMYH02006184
XM_006505635
XP_006505698
XM_006505634
XP_006505697
AC_000028
AAHY01056234
AAHY01056235
AAHY01056236
AAHY01056237
AAHY01056238
AAHY01056239
AAHY01056240
AAHY01056241
AAHY01056242
AAHY01056243
AAHY01056244
AAHY01056245
AAHY01056246
AAHY01056247
AAHY01056248
AAHY01056249
BC172648
AAI72648
XM_006713136
XP_006713199
XM_006713135
XP_006713198
XM_006713132
XP_006713195
XM_006713133
XP_006713196
XM_006713134
XP_006713197
AC_000135
ABBA01020466
ABBA01020467
ABBA01020468
ABBA01020469
ABBA01020470
M75986
M75987
XM_005265108
XP_005265165
XM_006236989
XP_006237051
XM_006236990
XP_006237052
XM_006236993
XP_006237055
XM_006236988
XP_006237050
XM_006236991
XP_006237053
XM_006236992
XP_006237054
XM_006236994
XP_006237056
AABR06032821
AABR06032822
AABR06032823
AABR06032824
AABR06032825
NT_022517
NW_921651
NW_001838876
AC_000046
Q59H91
NT_039353
NW_001030811
Q3UVA1
Q6NV80
Q8BQN0
Q8C7X9
Q8C8N0
NW_047695
NW_001084830
Q5BJS8
Q8C9F0
NW_000262
BG068206
1054963
1055287
1098969
17380349
204674
204675
204967
204969
60688455
81882514
1196648
123788591
129358
13096949
198412
26336805
26338934
26339686
46189240
53569
554171
74210346
81874734
81877206
81892040
81899258
81899351
17366467
4262086
46107962
559323
62087316
74741363
NT_086636
17367101
6006803
AAF00613
AF157625
NC_007320
NM_174841
NP_777266
NW_001494089
Q9TU34
NC_007117
NW_001513595
XM_690915
XP_696007
119584312
119584313
119584314
119584315
119584316
119584317
119584318
119584319
148666992
148666993
149036860

Swiss-Prot ID ITPR1_HUMAN
ITPR1_MOUSE
ITPR1_RAT
B4DER3_HUMAN
Q59H91_HUMAN
E9PDE9_HUMAN
B4DGH1_HUMAN
Q8BQN0_MOUSE
Q8C8N0_MOUSE
Q8C7X9_MOUSE
Q3UVA1_MOUSE

Cell Localization Endoplasmic reticulum membrane
Cytoplasmic vesicle
Secretory vesicle membrane
Cytoplasm
Perinuclear region
Endoplasmic reticulum
Plasma membrane

Ensembl ID ENSG00000150995
ENSP00000349597.4
ENST00000357086.10
ENSP00000306253.8
ENST00000302640.12
ENSP00000397885.2
ENST00000456211.8
ENSP00000497605.1
ENST00000649015.1
ENSP00000346595.8
ENST00000354582.11
ENSP00000498056.1
ENST00000650294.1
ENSP00000497026.1
ENST00000648309.1
ENSMUSG00000030102
ENSMUSP00000032192.6
ENSMUST00000032192.8
ENSMUSP00000144880.1
ENSMUST00000203615.2
ENSRNOG00000007104
ENSRNOP00000063885.3
ENSRNOT00000064025.3
ENSRNOP00000049540.4
ENSRNOT00000041130.5
ENSRNOP00000048661.4
ENSRNOT00000043646.4
ENSRNOP00000075403.1
ENSRNOT00000082723.1
ENSP00000349597
ENST00000357086
ENSP00000306253
ENST00000302640
ENSP00000397885
ENST00000456211
ENSP00000346595
ENST00000354582
ENSMUSP00000032192
ENSMUST00000032192
ENSRNOP00000063885
ENSRNOT00000064025
ENSRNOP00000049540
ENSRNOT00000041130
ENSRNOP00000048661
ENSRNOT00000043646
ENSRNOP00000043615
ENSRNOT00000040255

MGI ID MGI:96623
96623
97507

RGD ID 2933

TCDB ID 1.A.3.2.6

Unigene ID Hs.567295
Hs.715765
Mm.227912
Rn.2135
Rn.170703
Hs.708300
Bt.22305
Dr.115352
Hs.699169

Homologene ID 1673

Shape III-vertex

IPI ID IPI00230873
IPI00230877
IPI00230879
IPI00230881
IPI00944825
IPI00947857
IPI00949472
IPI00950591
IPI00218658
IPI00218659
IPI00218660
IPI00218661
IPI00218662
IPI00218664
IPI00333753
IPI00925443
IPI00117630
IPI00230018
IPI00230019
IPI00230020
IPI00230021
IPI00230023
IPI00469221
IPI00474081
IPI00982630
IPI00218663
IPI00795991
IPI00230875
IPI00210027
IPI00230878
IPI00230880

Microarray ID 161661_i_at
93895_s_at
94977_at
240052_at

Homo sapiens Chromosome position 3p26-p25
8q23-q24.1
3pter-p24.2

Ensembl Transcript ID ENST00000357086

ENSEMBL ENSG00000150995

FunctionalClass calcium ion transporter
inositol-1,4,5-triphosphate receptor
protein binding
calcium channel
calcium ion binding
inositol 1,4,5-triphosphate-sensitive calcium-release channel
ion channel
receptor
cation channel
calcium ion transmembrane transporter

Bos taurus Chromosome position 22

Mus musculus Chromosome position 6 48.0 cM
6 45.0 cM

KEGG pathway Calcium signaling pathway
Gap junction
GnRH signaling pathway
Long-term depression
Long-term potentiation
Phosphatidylinositol signaling system

ProteinAtlas SubcellularLocation Main location: Cytoplasm;Cytoskeleton (Intermediate filaments); Other location: ; Expression type: APE; Reliability: Very low

Rattus norvegicus Chromosome position 4q41

Ensembl Gene ID ENSG00000150995

ProteinAtlas NormalTissue Tissue: adrenal gland; Cell type: glandular cells; Level: None; Expression type: APE; Reliability: Medium
Tissue: appendix; Cell type: glandular cells; Level: None; Expression type: APE; Reliability: Medium
Tissue: appendix; Cell type: lymphoid tissue; Level: None; Expression type: APE; Reliability: Medium
Tissue: bone marrow; Cell type: hematopoietic cells; Level: None; Expression type: APE; Reliability: Medium
Tissue: breast; Cell type: glandular cells; Level: Low; Expression type: APE; Reliability: Medium
Tissue: bronchus; Cell type: respiratory epithelial cells; Level: None; Expression type: APE; Reliability: Medium
Tissue: cerebellum; Cell type: cells in granular layer; Level: None; Expression type: APE; Reliability: Medium
Tissue: cerebellum; Cell type: cells in molecular layer; Level: None; Expression type: APE; Reliability: Medium
Tissue: cerebellum; Cell type: Purkinje cells; Level: High; Expression type: APE; Reliability: Medium
Tissue: cerebral cortex; Cell type: glial cells; Level: None; Expression type: APE; Reliability: Medium
Tissue: cerebral cortex; Cell type: neuronal cells; Level: Medium; Expression type: APE; Reliability: Medium
Tissue: cervix, uterine; Cell type: glandular cells; Level: None; Expression type: APE; Reliability: Medium
Tissue: cervix, uterine; Cell type: squamous epithelial cells; Level: None; Expression type: APE; Reliability: Medium
Tissue: colon; Cell type: glandular cells; Level: None; Expression type: APE; Reliability: Medium
Tissue: duodenum; Cell type: glandular cells; Level: None; Expression type: APE; Reliability: Medium
Tissue: epididymis; Cell type: glandular cells; Level: Low; Expression type: APE; Reliability: Medium
Tissue: esophagus; Cell type: squamous epithelial cells; Level: None; Expression type: APE; Reliability: Medium
Tissue: fallopian tube; Cell type: glandular cells; Level: None; Expression type: APE; Reliability: Medium
Tissue: gall bladder; Cell type: glandular cells; Level: None; Expression type: APE; Reliability: Medium
Tissue: heart muscle; Cell type: myocytes; Level: Low; Expression type: APE; Reliability: Medium
Tissue: hippocampus; Cell type: glial cells; Level: None; Expression type: APE; Reliability: Medium
Tissue: hippocampus; Cell type: neuronal cells; Level: Medium; Expression type: APE; Reliability: Medium
Tissue: kidney; Cell type: cells in glomeruli; Level: None; Expression type: APE; Reliability: Medium
Tissue: kidney; Cell type: cells in tubules; Level: Low; Expression type: APE; Reliability: Medium
Tissue: lateral ventricle; Cell type: glial cells; Level: None; Expression type: APE; Reliability: Medium
Tissue: lateral ventricle; Cell type: neuronal cells; Level: Medium; Expression type: APE; Reliability: Medium
Tissue: liver; Cell type: bile duct cells; Level: None; Expression type: APE; Reliability: Medium
Tissue: liver; Cell type: hepatocytes; Level: None; Expression type: APE; Reliability: Medium
Tissue: lung; Cell type: macrophages; Level: Low; Expression type: APE; Reliability: Medium
Tissue: lung; Cell type: pneumocytes; Level: None; Expression type: APE; Reliability: Medium
Tissue: lymph node; Cell type: germinal center cells; Level: Low; Expression type: APE; Reliability: Medium
Tissue: lymph node; Cell type: non-germinal center cells; Level: Low; Expression type: APE; Reliability: Medium
Tissue: nasopharynx; Cell type: respiratory epithelial cells; Level: None; Expression type: APE; Reliability: Medium
Tissue: oral mucosa; Cell type: squamous epithelial cells; Level: None; Expression type: APE; Reliability: Medium
Tissue: ovary; Cell type: ovarian stroma cells; Level: None; Expression type: APE; Reliability: Medium
Tissue: pancreas; Cell type: exocrine glandular cells; Level: None; Expression type: APE; Reliability: Medium
Tissue: pancreas; Cell type: islets of Langerhans; Level: None; Expression type: APE; Reliability: Medium
Tissue: parathyroid gland; Cell type: glandular cells; Level: None; Expression type: APE; Reliability: Medium
Tissue: placenta; Cell type: decidual cells; Level: None; Expression type: APE; Reliability: Medium
Tissue: placenta; Cell type: trophoblastic cells; Level: None; Expression type: APE; Reliability: Medium
Tissue: prostate; Cell type: glandular cells; Level: Low; Expression type: APE; Reliability: Medium
Tissue: rectum; Cell type: glandular cells; Level: None; Expression type: APE; Reliability: Medium
Tissue: salivary gland; Cell type: glandular cells; Level: None; Expression type: APE; Reliability: Medium
Tissue: seminal vesicle; Cell type: glandular cells; Level: Low; Expression type: APE; Reliability: Medium
Tissue: skeletal muscle; Cell type: myocytes; Level: None; Expression type: APE; Reliability: Medium
Tissue: skin; Cell type: epidermal cells; Level: None; Expression type: APE; Reliability: Medium
Tissue: small intestine; Cell type: glandular cells; Level: None; Expression type: APE; Reliability: Medium
Tissue: smooth muscle; Cell type: smooth muscle cells; Level: None; Expression type: APE; Reliability: Medium
Tissue: spleen; Cell type: cells in red pulp; Level: Low; Expression type: APE; Reliability: Medium
Tissue: spleen; Cell type: cells in white pulp; Level: None; Expression type: APE; Reliability: Medium
Tissue: stomach, lower; Cell type: glandular cells; Level: Low; Expression type: APE; Reliability: Medium
Tissue: stomach, upper; Cell type: glandular cells; Level: Low; Expression type: APE; Reliability: Medium
Tissue: testis; Cell type: cells in seminiferus ducts; Level: Low; Expression type: APE; Reliability: Medium
Tissue: testis; Cell type: Leydig cells; Level: Low; Expression type: APE; Reliability: Medium
Tissue: thyroid gland; Cell type: glandular cells; Level: None; Expression type: APE; Reliability: Medium
Tissue: tonsil; Cell type: germinal center cells; Level: None; Expression type: APE; Reliability: Medium
Tissue: tonsil; Cell type: non-germinal center cells; Level: Low; Expression type: APE; Reliability: Medium
Tissue: tonsil; Cell type: squamous epithelial cells; Level: None; Expression type: APE; Reliability: Medium
Tissue: urinary bladder; Cell type: urothelial cells; Level: None; Expression type: APE; Reliability: Medium
Tissue: uterus, post-menopause; Cell type: cells in endometrial stroma; Level: None; Expression type: APE; Reliability: Medium
Tissue: uterus, post-menopause; Cell type: glandular cells; Level: None; Expression type: APE; Reliability: Medium
Tissue: uterus, pre-menopause; Cell type: cells in endometrial stroma; Level: None; Expression type: APE; Reliability: Medium
Tissue: uterus, pre-menopause; Cell type: glandular cells; Level: None; Expression type: APE; Reliability: Medium
Tissue: vagina; Cell type: squamous epithelial cells; Level: None; Expression type: APE; Reliability: Medium
Tissue: vulva/anal skin; Cell type: epidermal cells; Level: None; Expression type: APE; Reliability: Medium
Tissue: cervix
uterine; Cell type: squamous epithelial cells; Level: None; Expression type: APE; Reliability: Medium
uterine; Cell type: glandular cells; Level: None; Expression type: APE; Reliability: Medium