Pathway
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Alzheimer's Disease
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Osteoarthritis
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Thyroid Hormones Common non-Genomic Effects in Hyperthyroidism
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Adrenoceptors Physiological Effects
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PRL and CSH Action in Mammary Gland
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Insulin Signaling
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Prolactin Production
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LH and FSH Signaling and Steroidogenesis
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CD8+ T-Cell Activation
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T-Cell Receptor Signaling
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Lipoxin A4/FPR2-Related Neutrophil Depression
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AHR in Intestinal Cell Antimicrobial Barrier Maintenance
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Eicosanoids in Myeloid Cell Activation
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Neutrophil Activation via LTB4/Polyisoprenyl Phosphate Signaling
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Mast-Cell Activation without Degranulation through CYSLTR1/CYSLTR2 Signaling
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Vascular Smooth Muscle Cell/Pericyte Differentiation and Proliferation
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Tight Junction Assembly (Occludin)
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Tight Junction Assembly (Claudins)
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Adherens Junction Assembly (Cadherins)
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SCF/FBXW7 Complex
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Endothelin Signaling in Arterial Hypertension
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Endothelial Cell Dysfunction in Arterial Hypertension
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Aldosterone Synthesis Chronic Regulation
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BMP/TGF-beta Signaling Impairment in Pulmonary Hypertension
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Endothelial Cell Dysfunction in Pulmonary Hypertension
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Smooth Muscle Cell Dysfunction in Pulmonary Hypertension
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BMP2 and Canonical WNT Signaling in Pulmonary Artery Endothelial Cells
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Renin-Angiotensin-Aldosterone System in Myocardial ischemia
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Sebocyte Proliferation in Acne Vulgaris
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Androgen Induced Sebocyte Hyperfunction
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Keratinocyte Proliferation in Acne Vulgaris
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Telogen Maintenance in Androgenic Alopecia
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Androgens in Sebocyte Maturation
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Androgens Promote Scalp Dermal Papilla Regression
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Androgens Synthesis in Sebocytes
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Atopic Dermatitis Onset
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WNT Signaling in Melanoma
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IL17 Signaling in Psoriasis
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IL22 Induces Keratinocyte Proliferation in Psoriasis
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T-Cell Cytotoxic Response against Melanocytes in Vitiligo
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Donohue Syndrome Progression (Hypothesis)
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Tubular Cell Dysfunction in Progressive Diabetic Nephropathy
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Endothelial Cell Dysfunction in Progressive Diabetic Nephropathy
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Endothelial Cell Dysfunction in Early Diabetic Nephropathy
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Mesangial Cell Dysfunction in Diabetic Nephropathy
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Microangiopathy in Diabetic Neuropathy
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Proliferative Diabetic Retinopathy
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Hepatic Stellate Cells in non-Alcoholic Fatty Liver Disease
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beta-Cell Mass Regulation
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beta-Cell Function Inhibition by Ciclosporine and Tacrolimus (Rodent Model)
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FOXO1 and SREBP-1C Role in beta-Cell Suppression (Rodent Model)
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CDC73 Mutations Cause Hyperparathyroidism
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MEN1 Mutation in Hyperparathyroidism
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RET1 Mutation in Hyperparathyroidism
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Ethanol Induced Efects in Hyperprolactinemia
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Thyroid Dysfunction
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GLIS3 Targets in Thyroid Dysgenesis (Hypothesis)
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Thyroid Stimulating Hormone (TSH) Resistance in Congenital Hypothyroidism
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Overt Hypothyroidism, Primary
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CD4+T-Cell Response in Celiac Disease
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Cetuximab Resistance in Colorectal Cancer
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Metastatic Colorectal Cancer
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GUCY2C Signaling in Colorectal Cancer
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EGFR Nuclear Signaling in Colorectal Cancer
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CagA Phosphorylation Dependent Signaling
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Neurogenic Transcription Factors Role in Hirschsprung Disease
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EDN, NRG, NRTN, and GDNF/RET Signaling in Hirschsprung Disease
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Peutz-Jeghers Syndrome
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RARA Signaling in Acute Myeloid Leukemia (M3)
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Acute Myeloid Leukemia
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Myeloid Cell Differentiation Block in Leukemia
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B-Cell Acute Lymphoblastic Leukemia
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B-Cell Chronic Lymphocytic Leukemia
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Chronic Myeloid Leukemia
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Diffuse Large-B-Cell Lymphoma
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Diffuse Large-B-Cell Lymphoma ABC Subtype
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Lymphoma, GCB Subtype
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Primary Mediastinal B-cell Lymphoma (PMBL) Subtype
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Follicular Lymphoma
|
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Hodgkin Lymphoma
|
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Mantle Cell Lymphoma
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mTOR/NF-kB/BCR Signaling Disregulation in Mantle Cell Lymphoma
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WNT Canonical Signaling in Mantle Cell Lymphoma
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Hedgehog Signaling in Mantle Cell Lymphoma
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Mucosa-Associated Lymphoid Tissue (MALT) Lymphoma
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Splenic Marginal Zone Lymphoma
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TNFR/NF-kB Classical Pathway in Multiple Myeloma Plasma Cells
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IL6/IGF1/VEGFA Signaling in Multiple Myeloma
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Multiple Myeloma
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NOTCH Signaling in Multiple Myeloma
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TNFR/NF-kB Alternative Pathway in Multiple Myeloma Plasma Cells
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T-Cell Acute Lymphoblastic Leukemia
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T-Cell Genetic Rearrangements in Acute Lymphoblastic Leukemia
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NOTCH Signaling in Hepatocellular Carcinoma
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WNT Signaling in Hepatocellular Carcinoma
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Hepatocellular Carcinoma
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TP53 Signaling in Hepatocellular Carcinoma
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Growth Factor Signaling in Hepatocellular Carcinoma
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Pancreatic Ductal Carcinoma
|
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Growth Factor Signaling in Pancreatic Neoplasms
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TP53 Signaling in Pancreatic Neoplasms
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Pancreatic Neuroendocrine Tumors
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STK11 Signaling in Pancreatic Neoplasms
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TRPM7/8 in Pancreatic Adenocarcinoma
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TGFBR Signaling in Pancreatic Neoplasms
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Osteoclast Activation in Gout
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Ovulation Block
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Polycystic Ovary Syndrome
|
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FSH Action in Polycystic Ovary Syndrome
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PTPN22 Role in Rheumatoid Arthritis
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Synovial Fibroblast Proliferation in Rheumatoid Arthritis
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Osteoclast Activation in Rheumatoid Arthritis
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CCR5 Signaling in Macrophages
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Diabetes Induced Periodontitis
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Estrogen Effects on Pregnancy Gingivitis
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Li-Fraumeni Syndrome
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Hereditary Breast and Ovarian Cancer Syndrome
|
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Cowden Syndrome
|
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Dystrophin Glycoprotein Complex Signaling in Muscular Dystrophies
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IGF1 Role in Muscle Hypertrophy
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Myostatin-IGF1 Crosstalk in Skeletal Muscles in Muscular Dystrophies
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Osteoblast Function Decline in Osteoporosis
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Glioblastoma, Primary
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Glioblastoma, Secondary
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Astrocytoma
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Glioma Stem Cell Program Activation
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Ependymoma
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Medulloblastoma
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PHOX2B Effects in Neuroblastoma
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Growth Factor Signaling in Neuroblastoma
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Neuroblastoma
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ALK Associated Neuroblastoma
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Sonic Hedgehog Signaling in Neuroblastoma
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non-Hereditary Genetic Rearrangements in Neuroblastoma
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WNT Signaling in Breast Cancer
|
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ERBB/VEGFR/Akt Signaling in Breast Cancer
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IGF1R/AKT Signaling in Breast Cancer
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ESR1/ERBB Positive Luminal Breast Cancer
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Breast Cancer
|
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ESR1 Signaling in Breast Cancer
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NOTCH1 Signaling in Breast Cancer
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Endometrial Cancer
|
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Endometrioid Endometrial Cancer
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Clear Cell Endometrial Cancer and Papillary Serous Endometrial Cancer
|
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Coagulation Factors and PAR1/2 Receptors (F2R/F2RL1) in Endometriosis
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Leptin Role in Endometriosis
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Dioxin Role in Endometriosis
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Endometrioid Ovarian Carcinoma
|
|
Clear Cell Ovarian Carcinoma
|
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EGFR and PTAFR Signaling in Ovarian Cancer
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High-Grade Serous Ovarian Carcinoma
|
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Low-Grade Serous Ovarian Carcinoma
|
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Ovarian Cancer
|
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Mucinous Ovarian Carcinoma
|
|
INHA Gene Mutations in Granulosa Cell Proliferation
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FOXL2 Mutation in Ovarian Dysgenesis
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LH and FSH Signaling Impairment in Primary Ovarian Insufficiency
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MIF Role in Cholesteatoma
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EGF/cyclinD1 Signaling in Acquired Middle Ear Cholesteatoma
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IL6/JAK/STAT3 Signaling in Cholesteatoma
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HMGB1/RAGE Signaling in Middle Ear Cholesteatoma
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Subepithelial Fibroblasts in Middle Ear Cholesteatoma
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Cholesteatoma
|
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HPV E6 and E7 Induced Block of Apoptosis in Keratinocytes
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HPV Infection and Cancer
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HPV E5 Regulates EDNRA and EGFR Signaling Pathway in Keratinocytes
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Androgen Receptor/Akt Signaling
|
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Fatty Acid Synthase (FASN) Signaling
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Androgen Receptor/FKBP5 Signaling
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Androgen Receptor/Prostate Specific Antigen Signaling in Prostate Cancer
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Androgen Receptor/NKX3-1 Signaling
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Kruppel-like Factor 6 Signaling in Prostate Cancer
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Androgen Receptor/Beta-2-Microglobulin Signaling in Prostate Cancer
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Prostate Cancer
|
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beta-Catenin/Androgen Receptor Signaling in Prostate Cancer
|
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RNase L Signaling in Prostate Cancer
|
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Androgen Receptor/c-Met Signaling in Prostate Cancer
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FOXM1 Signaling in Prostate Cancer
|
|
TRPM8 Effects in Prostate Cancer (Hypothesis)
|
|
Androgen Receptor/GJB1 Signaling
|
|
Steroids Induced Cataract
|
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VEGFA in Neovascular Glaucoma
|
|
CAV1 Dependent Senescence of Lung Fibroblasts
|
|
WNT Signaling in Cystic Kidney Disease
|
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Polycystins Mutation Effects in Cystic Kidney Disease
|
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Endothelial Cell Dysfunction in Glomerulonephritis
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Mesangial Cell Dysfunction in Glomerulonephritis
|
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Interstitial Fibroblasts in Pyelonephritis
|
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Endothelial Cell Dysfunction in Pyelonephritis
|
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CD38 -> cADPR/Calcium Signaling
|
|
CD157 -> cADPR/Calcium Signaling
|
|
AGTR1 -> ARRB1/ARRB2 Signaling
|
|
Hedgehog Family -> ARRB1/ARRB2 Canonical Signaling
|
|
Tamoxifen Induced Endometrial Cancer
|
|
Clozapine Induced Granulocytopenia
|
|
EGFR Transactivation in Cancer and Non-Cancer Cells
|
|
TAM Receptor Signaling Activation in Cancer
|
|
PI3K/AKT/MTOR Signaling Activation in Cancer
|
|
DREAM Complex and FOXM1/MYBL2 Promote Cell Cycle Progression in Cancer
|
|
Hedgehog Signaling Activation in Cancer
|
|
Receptors and Adaptor Proteins Activated in Cancer
|
|
NOTCH Signaling Deregulation in Cancer
|
|
RAS/RAF/MAPK Signaling Activation in Cancer
|
|
WNT Canonical Signaling Activation in Cancer
|
|
NFKB Non-Canonical Signaling Activation in Cancer
|
|
STAT3 and NFkB Activate Inflammation-Induced Tumorigenesis
|
|
RAS/RAF/MAPK Signaling Activation by Blocking of Tumor Suppressors
|
|
Hedgehog Signaling Activation by Blocking of Tumor Suppressors
|
|
WNT Signaling Activation by Blocking of Tumor Suppressors
|
|
PI3K/AKT/MTOR Signaling Activation by Blocking of Tumor Suppressors
|
|
Hippo/YAP1 Signaling Deregulation in Cancer
|
|
NFKB Signaling Activation by Blocking of Tumor Suppressors
|
|
TERT/WNT Activation in Cancer
|
|
Oxidized LDL/OLR1 Activates Cell Proliferation in Cancer
|
|
ANGPT/TEK Stimulates Endothelial Cell Migration in Cancer
|
|
BSG (CD147) in Cancer Cells Motility, Invasion and Survival
|
|
Hyaluronic Acid, CD44 and HMMR in Cancer Cell Invasion and Survival
|
|
CDH2 Activation Promotes Cancer Cell Migration and Survival
|
|
Lipogenesis/Lipolysis Activation in Cancer Cells and Cancer-Associated Adipocytes
|
|
EZH2 Methyltransferase Role in Cancer
|
|
DNMT and MBD Families Activation in DNA Methylation in Cancer
|
|
Estrogens/ESR1 Genomic Canonical Signaling
|
|
Androgen Receptor non-Genomic Signaling
|
|
FOXO1 Signaling
|
|
WNT Canonical Signaling
|
|
Estrogens/ESR1 non-Genomic Signaling
|
|
EGFR Signaling
|
|
WNT Planar Cell Polarity (PCP) non-Canonical Signaling
|
|
Hedgehog Family Signaling
|
|
ROS in Angiotensin Mediated Cardiovascular Remodeling and Hypertrophy
|
|
n
|
|
cypa
|
|
PPARG inhibits phenotypes assotiated with psoriasis
|
|
H2A-K120, H2A-K119 and H3-K4
|
|
H2A-K119 and H3-K27
|
|
Epigenetic Modifications of H2A-K120, H2A-K119 and H3-K4
|
|
Overview. Diseases of the genitourinary system (chapter 13)
|
|
Overview. Infectious and parasitic diseases (chapter 2)
|
|
2_Hyperseborrhea in acne vulgaris
|
|
2_Osteoblast-mediated bone demineralization
|
|
1_Formation of cysts in polycystic kidney disease
|
|
3_The role of interstitial fibroblasts in pyelonephritis
|
|
3_Mesangial cell dysfunction in glomerulonephritis
|
|
2_Progesterone resistance stimulates endometriotic cell survival
|
|
1_Local estrogen production stimulates ectopic endometrium proliferation
|
|
3_Enhanced angiogenesis in endometriosis
|
|
2_Impaired steroidogenesis in PCOS
|
|
1_Endothelial cells stimulate vasoconstriction and thrombosis in pulmonary hypertension
|
|
3_1_Mucus accumulation in asthma
|
|
1_CD4+ T cell and epithelial cell response in celiac disease
|
|
4_Human papilloma virus E6 and E7 proteins promote epithelial cell survival
|
|
2_HIV - induced depletion of CD4+ T-cells
|
|
3_1_Beta-cell proliferation and compensation: proliferation
|
|
3_3_Beta-cell proliferation and compensation: recovery
|
|
4_1_Insulin resistance: insulin signaling
|
|
1_Microangiopathy in diabetic neuropathy
|
|
2_1_General pathways of thyroid hormone signaling
|
|
New Pathway
|
|
DIPG overview_2
|