Protein MAVS

URN urn:agi-llid:57506
Total Entities 0
Connectivity 1018
Name MAVS
Description mitochondrial antiviral signaling protein
Notes This gene encodes an intermediary protein necessary in the virus-triggered beta interferon signaling pathways. It is required for activation of transcription factors which regulate expression of beta interferon and contributes to antiviral immunity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]
ObjectType Protein

Pathway NOD-like Receptors
Antiviral Signaling through Pattern Recognition Receptors
TLR4 Signaling in Leukocytes
Toll-like Receptors in Sterile Inflammation
MAVS in Antiviral Innate Immune Response in Myocarditis
Dendritic Cell Activation in Systemic Lupus Erythematosis
Crohn's Disease
Macrophage Dysfunction
Dendritic Cell Dysfunction in Crohn's disease
pathway 4
Model of PPARG signaling in psoriasis
sars-cov no binding
dsRNA induces innate immunity and INFs in alveolar cells
Dendritic Cell Activation in COVID19
1_Insufficient activation of immune response in the middle ear epithelium cells in otitis media
1_Defects in response to pathogens in the gut promotes inflammation in Crohn's disease
3_Autophagy dysfunction in Crohn's disease

Group other partners for SARS

MedScan ID 57506

LocusLink ID 57506
228607
311430

Alias virus-induced signaling adaptor variant 1a
interferon-beta promoter stimulator protein 1
D430028G21Rik
CARD adaptor inducing interferon-beta
CARD adaptor inducing IFN-beta
mavs
mitochondrial antiviral signaling protein
MGC3260
VISA
Cardif
DKFZp547C224
IFN-beta promoter stimulator-1
OTTMUSP00000017159
FLJ41962
MGC25836
OTTHUMP00000030141
ips-1
OTTMUSP00000017160
IFN-B promoter stimulator 1
RP23-387C21.3
virus-induced signaling adaptor variant 1b
D430028G21
mitochondrial antiviral-signaling protein
mitochondrial anti-viral signaling protein
FLJ35386
KIAA1271
FLJ38051
MGC93707
DKFZp666M015
virus-induced signaling adaptor
FLJ27482
IPS1
CARD adapter inducing interferon beta
interferon beta promoter stimulator protein 1
putative NF-kappa-B-activating protein 031N
virus-induced-signaling adapter
virus-induced signaling adapter
virus-induced signaling adapter variant 1a
virus-induced signaling adapter variant 1b
CARD adapter inducing interferon-beta

GO ID 0050700
0019901
0035591
0002218
0071360
0042742
0051607
0045087
0032480
0045071
0051091
0043123
0071660
0071651
0002230
0032727
1902741
0032728
0035549
2000778
0032757
0002735
0042307
0001934
0060760
0045944
0032760
1904469
0060340
1900063
0006355
0007165
0016032
0016021
0031966
0005741
0005739
0005778
0039529
0002376
0032481
0016020
0005777
0051092
0005622
0005515
0033160
0042993
0004871
0005737
0019048

KEGG ID hsa:57506
mmu:228607
rno:311430

Organism Homo sapiens {Organism urn:agi-taxid:9606}
Mus musculus {Organism urn:agi-taxid:10090}
Rattus norvegicus {Organism urn:agi-taxid:10116}
Homo sapiens
Mus musculus
Rattus norvegicus

Mouse chromosome position 2

OMIM ID 609676

Rat chromosome position 3q36

Hugo ID 29233
HGNC:29233

Human chromosome position 20p13

Swiss-Prot Accession Q7Z434
Q7Z434.2
Q3U5B1
Q8VCF0
Q8VCF0.1
Q66HG9
Q66HG9.1
A8K6X0
B2BD33
B2BD34
F5H6C8
M1P2Z0
Q2HWT5
Q3I0Y2
Q5T7I6
Q86VY7
Q9H1H3
Q9H4Y1
Q9H8D3
Q9ULE9
A2ANC9

GenBank ID NC_000020
NR_037921
NM_001206491
NP_001193420
NM_020746
NP_065797
NG_030028
AL109804
AL353194
CH471133
EAX10481
EAX10482
CQ871280
CAH56821
AB033097
BAA86585
AB097003
BAC77356
AB232371
BAE79738
AK023799
BAB14684
AK056260
AK092705
AK095370
AK123956
BAC85734
AK130992
BAC85473
AK291785
BAF84474
AK296897
BAG59455
AL390136
AL833736
BC000073
BC028962
BC040719
BC040930
BC044952
AAH44952
BC052583
BC062310
BC063593
BM834250
BX649084
DB219666
DQ167126
ABA54890
DQ174270
AAZ80417
DQ181928
ABA19229
EF467323
ABR24161
EF467324
ABR24162
KC415005
AGF94754
Q7Z434
NC_000068
NM_144888
NP_659137
NM_001206382
NP_001193311
NM_001206385
NP_001193314
NM_001206383
NP_001193312
AL808128
CH466519
EDL28315
EDL28316
AK028421
BAC25940
AK028708
AK085038
AK153748
BAE32168
AK161823
AK177575
AK178965
AK181725
AK189538
AK193001
AK195306
AK203321
AX775773
CAE11586
BC020006
AAH20006
BC025825
AAH25825
BC031352
AAH31352
BC037391
AAH37391
DQ167127
ABA54891
DQ174271
AAZ80418
Q8VCF0
NC_005102
XM_006235034
XP_006235096
XM_006235036
XP_006235098
XM_008762179
XP_008760401
XM_006235035
XP_006235097
XM_006235037
XP_006235099
NM_001005556
NP_001005556
AC_000071
AAHX01025077
AC105811
AC110439
CH473949
EDL80235
BC081869
AAH81869
Q66HG9
XP_008760402
XM_008762180
EU832500
EU832581
CAI18851
CAM22812
AC_000152
CAI11041
AABR06026197
NC_018931
AAHY01020738
AMYH02036611
AC_000024
AMYH02036609
AMYH02036610
AAHY01020735
AAHY01020736
AAHY01020737
ABBA01053838
ACE86983
ACE87672
ABBA01053835
ABBA01053837
ABBA01053836

Swiss-Prot ID MAVS_HUMAN
MAVS_MOUSE
MAVS_RAT

Cell Localization Mitochondrion outer membrane
Mitochondrion
Peroxisome

Ensembl ID ENSG00000088888
ENSP00000413749.2
ENST00000416600.6
ENSP00000401980.2
ENST00000428216.4
ENSMUSG00000037523
ENSMUSP00000038339.5
ENSMUST00000041362.11
ENSMUSP00000105828.2
ENSMUST00000110199.2
ENSRNOG00000025295
ENSRNOP00000033476.3
ENSRNOT00000034146.3
ENSRNOP00000073053.1
ENSRNOT00000090764.1
ENST00000416600
ENSRNOT00000034146
ENSRNOT00000090764
ENSP00000401980
ENSP00000413749
ENST00000428216.3
ENSMUSP00000038339
ENSMUST00000041362
ENST00000428216
ENSMUST00000110199
ENSMUSP00000105828
ENSRNOP00000033476
ENSRNOP00000073053

MGI ID MGI:2444773
2444773

RGD ID 1359371

Unigene ID Rn.34996
Mm.287226
Hs.570362

Homologene ID 17004

IPI ID IPI00020719
IPI00411577
IPI00411576
IPI00122075
IPI00364200