Protein SRC

URN urn:agi-llid:6714
Total Entities 0
Connectivity 9981
Name SRC
Description v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog
Notes This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
Primary Cell Localization Cytoplasm
Class Protein kinase
ObjectType Protein

Pathway Skin Aging
High Fat Diet Activates cAMP Related Exocytosis in Synapse and Endocrine Cell
Leptin and CCK8 Activate Nodose Ganglia Neuron
I-cell: CCK-8 Secretion and Regulation of Eating Behavior
Dopamine Receptors Signaling
Thyroid Hormones Common non-Genomic Effects in Hyperthyroidism
CXC Chemokine Receptor Signaling
CC Chemokine Receptor Signaling
Plasmin Effects in Inflammation
Platelet Activation via Adhesion Molecules
Proplatelet Maturation
Toll-like Receptor Independent Sterile Inflammation
Eat me Signal: Apoptotic Cell Induces Phagocytosis
Eicosanoids in Myeloid Cell Activation
Eosinophil Activation
Mast-Cell Activation without Degranulation
Mast-Cell Activation without Degranulation through KIT/F2R Signaling
Mast-Cells De Novo Synthesized Mediators via IgE Independent Signaling
CD16/CD14 Proinflammatory Monocyte Activation
anti-Inflammatory Function of Macrophage M2 Lineage
Neutrophil Chemotaxis
Vascular Smooth Muscle Cell/Pericyte Migration and Proliferation
Vascular Endothelial Cell Activation by Blood Coagulation Factors
Vascular Endothelial Cell Activation by Growth Factors
Vascular Endothelial Cell Permeability Activation
Potassium Flux Regulation
GFs/TNF -> Ion Channels
Nociception Expression Targets Signaling
Vascular Motility
Ca2+ Flux Regulation
ADRA2C/ADRB2 -> Vasoconstriction
ADRA2C/ADRB2 -> Synaptic Endocytosis
ADRB1 -> Prostaglandin Generation
DRD2 Expression Targets
DRD2 -> TRPC1 Transcription
DRD2/4 -> Membrane Transport
CHRM1 -> IL2 Production
OPRK -> Pain Perception
IL6 Expression Targets -> Nociception
GABA(B)R -> Postsynaptic Inhibition
NTRK1/2/3 -> Acetylcholine Production
EPHB -> NMDA Receptor Activation
Vitamine D Deficite and Dentin Formation
G0/G1 Phase Transition
Adherens Junction Assembly (Nectin)
Focal Junction Assembly
Adherens Junction Assembly (Cadherins)
Proteins Involved in Arterial Hypertension
Endothelin Signaling in Arterial Hypertension
Arterial Hypertension
Endothelial Cell Dysfunction in Arterial Hypertension
Aldosterone Synthesis Chronic Regulation
Smooth Muscle Cell Dysfunction in Arterial Hypertension
TRPM4/6/7/8 Signaling in Arterial Hypertension (Hypothesis)
Proteins Involved in Pulmonary Hypertension
Endothelial Cell Dysfunction in Pulmonary Hypertension
Myocardial Remodeling
Proteins Involved in Myocarditis
Vascular Reactivity in Raynaud Disease
Melanoma
Proteins Involved in Melanoma
Vitiligo
Apoptosis of Melanocyte in Vitiligo
Macrophage Function in Diabetes Mellitus Type 1
Treg-Cell Activation in Diabetes Mellitus
Tubular Cell Dysfunction in Progressive Diabetic Nephropathy
Endothelial Cell Dysfunction in Progressive Diabetic Nephropathy
Mesangial Cell Dysfunction in Diabetic Nephropathy
Proliferative Diabetic Retinopathy
Hepatic Stellate Cells in non-Alcoholic Fatty Liver Disease
Hyperparathyroidism, Neonatal Severe
Bone Remodeling in Hyperthyroidism
KISS1 Production Impairment in Hypogonadotropic hypogonadism
Hypoparathyroidism, Primary
Proteins Involved in Obesity
Enterocyte Mediated Mucosal Damage in Celiac Disease
Proteins Involved in Colorectal Neoplasms
Metastatic Colorectal Cancer
GUCY2C Signaling in Colorectal Cancer
OipA Signaling in Helicobacter Pylori Infection
CagA Phosphorylation Independent Signaling
CagA Phosphorylation Dependent Signaling
B-Cell Acute Lymphoblastic Leukemia
B-Cell Chronic Lymphocytic Leukemia
Chronic Myeloid Leukemia
Proteins Involved in Chronic Myeloid Leukemia
Follicular Lymphoma
Hodgkin Lymphoma
Mucosa-Associated Lymphoid Tissue (MALT) Lymphoma
Osteoclast Activation in Multiple Myeloma
IL6/IGF1/VEGFA Signaling in Multiple Myeloma
Multiple Myeloma
Proteins Involved in Hepatocellular Carcinoma
Hepatocellular Carcinoma
Growth Factor Signaling in Hepatocellular Carcinoma
Proteins Involved in Pancreatic Cancer
Pancreatic Ductal Carcinoma
Growth Factor Signaling in Pancreatic Neoplasms
Pancreatic Neuroendocrine Tumors
Eosinophil Activation and Degranulation in Asthma
Airway Smooth Muscle Cell High Rate Proliferation
IgE Induces Airway Smooth Muscle Cell Proliferation
Airway Smooth Muscle Cell Contraction
Mast-Cell Related Chemokines Signaling in Asthma
Osteoclast Activation in Gout
Osteoclast Activation in Psoriatic Arthritis
Synovial Fibroblast Proliferation in Rheumatoid Arthritis
Osteoclast Activation in Rheumatoid Arthritis
Autocrine Cytokine/Chemokine Loops in Systemic Scleroderma
Skin Fibrosis
WHIM Syndrome
CCR5 Signaling in Macrophages
Macrophage Survival through CCR5 and CXCR4 Mediated Signaling
Estrogen Effects on Pregnancy Gingivitis
Hereditary Hemorrhagic Telangiectasia
Cowden Syndrome
Glutamate Toxiicity Effects on Striatum Medium Spiny Neurons in Hantington's Disease
Ca2+ Overload in Muscular Dystrophies
Muscular Dystrophies
Dystrophin Glycoprotein Complex Signaling in Muscular Dystrophies
Proteins Involved in Osteopetrosis
Proteins Involved in Osteoporosis
Osteoclast Activation in Postmenopause
Proteins Involved in Alzheimer's Disease
Proteins Involved in Epilepsy
BDNF Upregulation Triggered by Seizures
HMGB1 and IL1B in Neuronal Hyperexcitation
Glioblastoma, Primary
Medulloblastoma
Growth Factor Signaling in Neuroblastoma
Neuroblastoma
Proteins Involved in Neuroblastoma
Microglia and Motor Neuron Interaction Dysregulation
SPP1 Induced Survival of Myelin Specific T-Cells in Multiple Sclerosis
Proteins Involved in Breast Cancer Related to ESR1 Signaling Pathway
Proteins Involved in Breast Cancer Related to ERBB2/VEGFR/Akt Signaling Pathway
ERBB/VEGFR/Akt Signaling in Breast Cancer
IGF1R/AKT Signaling in Breast Cancer
ESR1/ERBB Positive Luminal Breast Cancer
Proteins with Altered Expression in Breast Cancer
Proteins Involved in Breast Cancer Related to IGF1R/Akt Signaling Pathway
Breast Cancer
ESR1 Signaling in Breast Cancer
Endometrial Cancer
Endometrioid Endometrial Cancer
Clear Cell Endometrial Cancer and Papillary Serous Endometrial Cancer
Angiogenesis in Endometriosis
Coagulation Factors and PAR1/2 Receptors (F2R/F2RL1) in Endometriosis
Proteins Involved in High-Grade Serous Ovarian Carcinoma
Endometrioid Ovarian Carcinoma
Proteins Involved in Endometrioid Ovarian Carcinoma
Clear Cell Ovarian Carcinoma
Proteins Involved in Mucinous Ovarian Carcinoma
High-Grade Serous Ovarian Carcinoma
Low-Grade Serous Ovarian Carcinoma
Proteins Involved in Low-Grade Serous Ovarian Carcinoma
Ovarian Cancer
Proteins Involved in Clear Cell Ovarian Carcinoma
Mucinous Ovarian Carcinoma
MIF Role in Cholesteatoma
Cholesteatoma
HPV E5 Regulates EDNRA and EGFR Signaling Pathway in Keratinocytes
Androgen Receptor Coregulator ARA55 (TGFB1I1) in Prostate Cancer
Prostate Cancer
TRPM8 Effects in Prostate Cancer (Hypothesis)
Proteins Involved in Prostate Cancer
Ca2+ Toxicity in Lens Cells
Proteins Involved in Cataract
VEGFA in Neovascular Glaucoma
Proteins Involved in Noise-Induced Hearing Loss
Alveolar Macrophages Dysfunction in COPD
VEGFA Low Expression Level in Chronic Bronchitis
VEGFA High Expression Level in Pulmonary Emphysema
T-Cell Cytotoxic Activation
Alveolar Epithelial Cell Dysfunction in COPD
Proteins Involved in Polycystic Kidney Disease
Proteins Involved in Glomerulonephritis
Plasmin Role in Glomerulonephritis
Endothelial Cell Dysfunction in Glomerulonephritis
Mesangial Cell Dysfunction in Glomerulonephritis
Interstitial Fibroblasts in Pyelonephritis
Sertoli Cells Dysfunction Causes Male Infertility
CD157/ITGB2 Signaling in Myeloid Cell
CD38 -> cADPR/Calcium Signaling
ANGPT1 -> CREB/CREBBP Expression Targets
ANGPT2 -> AP-1/CREBBP/MYC Expression Targets
AREG -> NFATC Expression Target
AREG -> CREB/CREBBP Expression Targets
AREG -> NCOR2 Expression Targets
AREG -> CTNN Expression Targets
AREG -> HIF1A Expression Targets
AREG -> STAT Expression Targets
AREG -> AP-1 Expression Targets
Noradrenaline/Gs Expression Targets
Epinephrine/Gs Expression Targets
Acetylcholine Expression Targets
Dopamine/Gi Expression Targets
Aryl Hydrocarbon Receptor Genomic and non-Genomic Signaling
BTC -> NFATC Expression Targets
BTC -> AP-1/ATF/CREB Expression Targets
BTC -> CTNN Expression Targets
BTC -> STAT Expression Targets
AGTR1 -> ARRB1/ARRB2 Signaling
INSR -> ARRB2/AKT/SRC Signaling
ARRB1/ARRB2 non-CanonicalSignaling and HedgehogFamily
CD72 -> NF-kB Expression Targets
CD8 -> NF-kB Expression Targets
CD80 -> NFATC Expression Targets
CD86 -> NFATC Expression Targets
EGF -> CTNN Expression Targets
EGF -> HIF1A Expression Targets
EGF -> AP-1/ATF Expression Targets
EGF -> CREB/CREBBP/ELK/SRF/MYC Expression Targets
EGF -> MEF/MYOD/NFATC Expression Targets
EGF -> TP53 Expression Targets
EGF -> NCOR2 Expression Target
EGF -> STAT Expression Targets
EGFR -> NCOR2 Signaling
EGFR/ERBB3 -> MEF/MYOD/NFATC/MYOG Signaling
EGFR -> CTNND Signaling
EGFR/ERBB2 -> TP53 Signaling
EGFR/ERBB2 -> CTNNB Signaling
EGFR/ERBB2 -> HIF1A Signaling
EGFR -> AP-1/ATF2 Signaling
EGFR -> AP-1/CREB/ELK/SRF/MYC Signaling
EGFR/ERBB -> STAT Signaling
EREG -> CREB Expression Target
EREG -> CTNNB/CTNND Expression Target
EREG -> STAT Expression Targets
EREG -> HIF1A Expression Target
EREG -> AP-1/ATF Expression Targets
Erythropoietin -> AP-1/MYC/CREB Expression Targets
F2 -> AP-1/CREB/ELK/SRF/SP1 Expression Targets
F2 -> STAT1/NF-kB Expression Targets
PLG -> AP-1/CREB/ELK/SRF/SP1 Expression Targets
PLG -> STAT1/NF-kB Expression Targets
FGF9 -> AP-1/CREB/MYC Expression Targets
FGF10 -> AP-1/CREB/CREBBP/MYC Expression Targets
FGF2 -> STAT Expression Targets
FGF1 -> AP-1/CREB/ELK/SRF/MYC Expression Targets
FGF1 -> NCOR2 Expression Target
FGF8 -> AP-1/CREB/MYC Expression Targets
FGF10 -> STAT Expression Targets
FGF18 -> AP-1/CREB Expression Targets
FGF23 -> NCOR2 Expression Targets
FGF1 -> STAT Expression Targets
FGF2 -> NCOR2 Expression Targets
FGF4 -> AP-1/MYC Expression Targets
FGF7 -> AP-1/CREB/CREBBP/MYC Expression Targets
FGF2 -> AP-1/CREB/CREBBP/ELK/SRF/MYC Expression Targets
FGFR1 -> STAT Signaling
FGFR -> AP-1/CREB/CREBBP/ELK/SRF/MYC Signaling
Glutamate/Gq Expression Targets
HBEGF -> STAT Expression Targets
HBEGF -> AP-1/ATF Expression Targets
HBEGF -> TP53 Expression Targets
HBEGF -> HIF1A Expression Targets
HBEGF -> MEF/MYOD Expression Target
HBEGF -> CREB/MYC Expression Targets
HGF -> STAT Expression Targets
HGF -> AP-1/CREB/ELK/SRF/MYC Expression Targets
HGFR -> STAT Signaling
HGFR -> AP-1/CREB/MYC Signaling
EGFR Transactivation in Cancer and Non-Cancer Cells
TAM Receptor Signaling Activation in Cancer
Receptors and Adaptor Proteins Activated in Cancer
Proteins with Altered Expression in Cancer-Associated Sustaining of Proliferative Signaling
G0/G1 Cell Cycle Phase Transition Activation in Cancer
STAT3 and NFkB Activate Inflammation-Induced Tumorigenesis
STAT3 Inhibits Maturation of Dendritic Cells and Facilitates Cancer Progression
VEGFA Dependent Angiogenesis in Cancer
VEGF Independent Angiogenesis in Cancer
Integrins in Cancer Cell Motility, Invasion and Survival
Proteins with Altered Expression in Cancer Metastases
Epithelial to Mesenchymal Transition in Cancer: Overview
Hyaluronic Acid, CD44 and HMMR in Cancer Cell Invasion and Survival
CDH2 Activation Promotes Cancer Cell Migration and Survival
CFL1 in Cancer Cell Motility
Invadopodia Formation in Cancer Cells
Myeloid Derived Suppressor Cells in Cancer Immune Escape
IGF1 -> MEF/MYOD/MYOG Expression Targets
IGF2/MEF/MYOD Expression Targets
IGF2 -> HIF1A/MYC Expression Targets
IGF1 -> ELK/SRF/HIF1A/MYC/SREBF Expression Targets
Insulin -> MEF/MYOD Expression Targets
Insulin -> ELK/SRF/HIF1A/MYC/SREBF Expression Targets
PECAM -> STAT Signaling
IGF1R -> ELK/SRF/HIF1A/MYC/SREBF Signaling
IGF1R -> MEF/MYOD/MYOG Signaling
FibronectinR -> AP-1/ELK/SRF/SREBF Signaling
MacrophageR -> CEBPB -> NF-kB Signaling
CTGF -> AP-1/CREB/MYC Expression Targets
CTGF -> NCOR2 Expression Target
ICAM1 Expression Targets
Fibrinogen Expression Targets
IL6ST -> STAT5B Signaling
IL6 Expression Targets
IL16-> ATF/CREB/CREBBP Expression Target
Morphine Expression Targets
Proteins/Ions Transporters -> Expression Targets in Lymphoid System and Blood
NRG1 -> MEF/MYOD Expression Targets
NRG1 -> CREB/CREBBP/ELK/SRF/MYC Expression Targets
NRG1 -> TP53 Expression Target
NRG1/Catenin Expression Targets
NRG1 -> STAT Expression Targets
NRG1 -> AP-1/ATF Expression Targets
NRG1 -> HIF1A Expression Target
NGF -> SMAD3/NF-kB Expression Targets
NGF -> AP-1/TP53/MYC Expression Targets
NGF -> FOXO/MYCN/ELK-SRF Expression Targets
BDNF Expression Targets
NGF -> CREB/CEBPB/MEF2A Expression Targets
Adenosine Expression Targets
PDGFC -> STAT Expression Target
PDGFB -> AP-1/CREB/MYC Expression Target
PDGFC -> CREB Expression Target
PDGFD -> AP-1 Expression Targets
PDGFD -> STAT Expression Targets
PDGF -> AP-1/CREB/CREBBP/MYC Expression Targets
PDGF -> STAT Expression Targets
PDGFB -> STAT Expression Target
KIT -> MITF Signaling
PDGFR -> STAT Signaling
CSF2 -> STAT Signaling
PDGFR -> AP-1/MYC Signaling
AVP/Gs -> CREB/ELK/SRF/AP-1/EGR Expression Targets
POMC Expression Targets
AVP/Gs -> MEF/MYOD/NFATC/MYOG Expression Targets
AVP/Gq -> STAT Expression Targets
IFNA1/Gq Expression Targets
AVP/Gs -> STAT Expression Targets
AVP/Gq -> MEF/MYOD/NFATC/MYOG Expression Targets
AVP/Gq -> CREB/ELK/SRF/AP-1/EGR Expression Targets
PDCD1 -> ATF/CREB/CREBBP Expression Targets
AngiopoietinR -> AP-1 Signaling
EphrinB -> Cytoskeleton Signaling
GDNF -> HSF1 Signaling
EphrinB -> MAPK/JUN/FOS Signaling
NTRK -> FOXO/MYCN Signaling
NTRK -> AP-1/CREB/ELK/SRF/MYC/SMAD3/TP53 Signaling
CSF1 -> STAT Expression Targets
GAS6 -> AP-1/CREB Expression Targets
FIGF -> AP-1 Expression Target
FIGF -> NCOR2 Expression Target
KITLG -> AP-1/CREB/CREBBP/MYC Expression Targets
GDNF -> HSF1 Expression Targets
CSF1 -> AP-1/CREB/CREBBP/MYC Expression Targets
PGF -> AP-1/CREB/CREBBP/MYC Expression Targets
FLT3LG -> AP-1/CREB/CREBBP Expression Targets
Ras-GRF Regulation Signaling
Androgen Receptor non-Genomic Signaling
FOXO1 Signaling
MERTK Signaling
Ras-GAP Regulation Signaling
PI3K/RAC1 Signaling
VEGF Signaling
Estrogens/ESR1 non-Genomic Signaling
EGFR Signaling
ERK5/MAPK7 Signaling
ERK/MAPK Canonical Signaling
TCR -> CREB/CREBBP/ATF Expression Targets
TCR -> NFAT Expression Targets
TCR -> AP-1 Expression Targets
TGFA -> STAT Expression Targets
TGFA -> CTNNB/CTNND Expression Targets
TGFA -> TP53 Expression Targets
TGFA -> HIF1A Expression Targets
TGFA -> MEF/MYOD/NFATC Expression Targets
TGFA/AP-1/ATF Expression Targets
TGFA -> CREB/CREBBP/ELK-SRF/MYC Expression Targets
CD40LG -> NF-kB/ELK/SRF -> CREB/NFATC Expression Targets
TNFSF13B Expression Targets
TNFRSF5/13B -> NFATC1 Signaling
Thrombopoietin -> AP-1/CREB/CREBBP/MYC Expression Targets
ROS in Angiotensin Mediated Cardiovascular Remodeling and Hypertrophy
VEGFA -> ATF/CREB/ELK-SRF Expression Targets
VEGFC -> CTNNB Expression Target
VEGFA -> NFATC Expression Targets
VEGFA -> STAT Expression Targets
VEGFC -> ATF Expression Target
VEGFA -> AP-1/CREBBP/MYC Expression Targets
VEGFA -> CTNNB/CTNND Expression Targets
VEGFA -> NCOR2 Expression Target
VEGFR -> CTNND Signaling
VEGFR -> CTNNB Signaling
VEGFR -> NFATC Signaling
VEGFR -> STAT Signaling
VEGFR -> AP-1/CREB/MYC Signaling
VEGFR -> ATF/CREB/ELK-SRF Signaling
WNT5A Expression Targets
Model of PPARG signaling in psoriasis
PPARG negative regulators and targets
Model of PPARG related pathways in psoriasis (short version)
1_Osteoclast-mediated bone resorption in postmenopausal women
2_Osteoblast-mediated bone demineralization
3_The role of interstitial fibroblasts in pyelonephritis
3_Mesangial cell dysfunction in glomerulonephritis
1_Local estrogen production stimulates ectopic endometrium proliferation
3_Enhanced angiogenesis in endometriosis
1_Disruption of luteinizing hormone and follicle-stimulating hormone secretion in PCOS
1_Endothelial cells stimulate vasoconstriction and thrombosis in pulmonary hypertension
1_Cigarette smoke causes dysfunction and production of inflammatory mediators in alveolar epithelial cells
3_Role of alveolar macrophages in pulmonary tissue destruction in COPD
2_1_Eosinophilia and neutrophilia in asthma: eosinophil migration and activation
4_1_Airway smooth muscle cells contraction
4_2_Airway smooth muscle cells proliferation and airway tissue remodeling
1_CD4+ T cell and epithelial cell response in celiac disease
2_1_General pathways of thyroid hormone signaling
drug-target moltransport
Model of PPARG signaling in psoriais (tested)
mapk1 protein modificators

Group Proteins Involved in B-Cell Acute Lymphoblastic Leukemia
Proteins Involved in Cowden Syndrome

Source curated
ResNet
GO component

MedScan ID 6714

LocusLink ID 6714
20779
83805
99351
280929
535742
325084

Alias tyrosine kinase pp60c-src
SRC proto-oncogene, nonreceptor tyrosine kinase
proto-oncogene c-Src
tyrosine protein kinase c-src
SRC proto-oncogene, non receptor tyrosine kinase
SRC
Rous sarcoma oncogene
SRC-1 kinase
Schmidt-Ruppin A-2 viral oncogene homolog
Src protein kinase
neuronal proto-oncogene tyrosine-protein kinase Src
v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog
RP5-823N20.1
Protooncogene Src, Rous sarcoma
p60-Src
pp60c-src
protooncogene src
OTTHUMP00000174478
tyrosine kinase SRC-1
c-Src
RP23-169M4.1
Src tyrosine kinase
v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
OTTMUSP00000019027
p60c-src
proto-oncogene Src
OTTHUMP00000174476
SRC I
OTTMUSP00000017316
OTTHUMP00000174477
v-Src
Src PTK
OTTMUSP00000019029
c-Src tyrosine kinase
THC6 gene
v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog
Proto-oncogene tyrosine-protein kinase Src
SRC1
OTTMUSP00000019028
ASV
THC6
tyrosine-protein kinase SRC-1
AW259666
tyrosine protein kinase pp60-c-src
SRC proto-oncogene, non-receptor tyrosine kinase
Src protein tyrosine kinase
expressed sequence AW259666
Schmidt-Ruppin A-2) viral oncogene homolog
SRC SH2-domain
SRC SH3-domain
tyrosine protein kinase SRC-1
chromosome
fc54g04
protein-tyrosine kinase
scaffold
wu:fc54g04
Src N1

EC Number 2.7.10.2
2.7.10.1
2.7.1.112

GO ID 0005524
0070700
0042169
0005070
0045296
0071253
0019899
0046875
0030331
0070851
0020037
0005158
0005178
0044325
0016301
0019900
0004715
0051219
0008022
0005080
0004672
0004713
0097110
0005102
0031625
0038128
0038096
0007186
0031295
0032148
0034332
0086098
0007411
0045453
0060444
0007049
0030154
0008283
0098609
0071398
0071498
0070301
0071456
0032869
0071222
0071375
0036120
0071393
0035635
0048013
0007173
0030900
0007229
0035556
0050900
0016236
2000811
0043066
0043154
2001237
0051895
2001243
0051902
0032463
0051974
0032211
0045892
0048011
0042476
0048477
0036035
0018105
0038083
0018108
0030168
2000573
0070374
0043406
0043065
0090263
0045737
0050715
0035306
0010634
0010907
0046628
0033625
2000394
1903997
2000386
0050731
0043552
0014068
2000588
0071803
0031954
0051897
1900182
0010954
0071902
0051057
0014911
0045893
0001545
0050847
0046777
0031648
0045124
2001286
0060491
0022407
2000641
0010632
0033146
0098962
0043393
0043114
0010447
0051602
0070555
0009612
0051385
0031667
0009615
0007172
0007165
0002223
0043149
0034446
0045056
0007179
0007169
0060065
0048010
0016032
0005884
0005901
0005737
0005829
0070062
0031234
0098978
0005770
0005764
0005743
0005739
0043005
0005634
0048471
0005886
0002102
0014069
0099091
0032587
0050839
0000166
0019904
0019901
0044877
0016740
0007155
0016477
0034614
0071560
0002376
0016310
0045785
0010628
1902533
0051222
0006468
0005856
0016020
1905587
0010641
0042493
0070542
0042542
0051427
0007417
0045087
0030520
0048008
0051726
0042127
0071801
0016337
0032403
0007265
0007596
0008543
0061024
0016772
0005622
0019048
0016044
0007243
0010740
0001101
0006950
0034329
0071445
0044419
0019717
0008152
0005515
0016021
0004674
0000074
0004872
0007242
0050875
0046854
0046934

KEGG ID hsa:6714
mmu:20779
rno:83805

MedLine Reference 11249956
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6255214
6320193
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7512695
7530829
7539296
7542761
7617039
7685105
7689855
7846766
7909754
7911089
7958873
7959737
7961761
8001130
8034307
8095010
8145850
8270638
8634424
8661722
8672127
8690046
8756343
8812502
8849724
8858346
8983085
9006082
9062339
9160879
9195991
9257949
9315092
9325263
9344858
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9373037
9374500
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9687503
10070972
10075741
10092678
10187839
10195142
10205168
10206955
10339567
10358079
10362724
10391903
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10455194
10458595
10462375
10467411
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10527887
10544291
10635328
10657632
10681522
10688651
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10734107
10777539
10777553
10787408
10838070
10846184
10858437
10871840
10884433
10899172
10918587
10931187
10945997
10959835
10971656
10973497
10978326
11007774
11013230
11024032
11039464
11071635
11106497
11113628
11127814
11152665
11279024
11279199
11279201
11294897
11309200
11313464
11350938
11353545
11373296
11375989
11379820
11382764
11445557
11481331
11483589
11483655
11514593
11524430
11593413
11602604
11708798
11713277
11723131
11724572
11739737
11741599
11741929
11751924
11781820
11834516
11854294
11872746
11875070
11877451
11884411
11923305
11927607
11934669
11940572
11964172
11971983
11983694
11994743
12011079
12014986
12048194
12052863
12060669
12063167
12091389
12095943
12145209
12153558
12162444
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12235291
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12454018
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12554790
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12588871
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12730241
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12771149
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12795607
12808100
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12829810
12846735
12878163
12907754
12932824
12933816
12939401
12947321
12972425
12975382
1310678
1379745
1383690
1384654
14504278
14517306
14551213
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14617636
14627343
14661060
14670955
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14687660
14688263
14702039
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14707140
14739293
14761972
14766744
14963038
15001550
15033452
15060621
15062576
15069201
15075377
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15271991
15272013
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2681803
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10082587
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6253989
8402898
8805372

Organism Homo sapiens {Organism urn:agi-taxid:9606}
Mus musculus {Organism urn:agi-taxid:10090}
Rattus norvegicus {Organism urn:agi-taxid:10116}
Homo sapiens
Mus musculus
Rattus norvegicus
Bos taurus
Danio rerio

Mouse chromosome position 2 78.35 cM
2 89.0 cM

OMIM ID 190090
114500
616937

Rat chromosome position 3q42

Hugo ID 11283
HGNC:11283

Human chromosome position 20q11.23
20q12-q13

Swiss-Prot Accession P12931
P12931.3
F8WI90
P05480
P05480.4
Q9WUD9
Q9WUD9.4
E1P5V4
Q76P87
Q86VB9
Q9H5A8
Q2M4I4
G3V776
Q45QJ2
Q9JJ10
Q80XU2
Q71UK5
Q9H7V3
Q3UKD6
SRC_HUMAN
SRC_MOUSE
Q2M4I4_MOUSE
Q80XU2_MOUSE
Q9JJ10_RAT
SRC_CHICK
NDEL1_MOUSE

PIR ID A26891
A43610

GenBank ID NC_000020
NM_005417
NP_005408
XM_017028026
XP_016883515
XM_017028024
XP_016883513
XM_017028025
XP_016883514
XM_011529013
XP_011527315
NM_198291
NP_938033
XM_017028027
XP_016883516
NG_023033
AF077754
AAC29427
AH002989
AAA60584
AL034422
AL133293
AL390014
AX405748
CAD34855
CH471077
EAW76062
EAW76063
EAW76064
EAW76065
EAW76066
EAW76067
CS566144
CAN37623
KF456893
M34469
AAB59543
X02647
CAA26485
X03995
X03996
X03997
X03998
X03999
X04000
AF272982
AK024281
BAB14871
AK091756
AW135290
BC011566
AAH11566
BC051270
AAH51270
CD364525
HY016645
Z18364
P12931
NC_000068
XM_011239404
XP_011237706
XM_006499066
XP_006499129
XM_011239402
XP_011237704
XM_011239403
XP_011237705
XM_006499063
XP_006499126
NM_009271
NP_033297
NM_001025395
NP_001020566
XM_006499065
XP_006499128
AJ312258
AJ312259
AJ312260
AJ312261
AJ312262
AJ312263
AJ312264
AJ313104
AJ313176
AJ313177
AL672259
AY902331
AAX90616
CH466551
EDL06234
M61221
M61225
AK017629
AK146056
BAE26865
AK182969
AK182983
AK189521
AK190301
AK192339
AK200868
AK201096
AK208623
AK216314
CD355175
CX218263
M17031
AAA40135
P05480
NC_005102
XM_017592067
XP_017447556
XM_017592066
XP_017447555
XM_017592070
XP_017447559
XM_017592065
XP_017447554
XM_017592069
XP_017447558
XM_017592068
XP_017447557
XM_017592071
XP_017447560
XM_008762388
XP_008760610
XM_008762387
XP_008760609
XM_017592072
XP_017447561
NM_031977
NP_114183
AC_000071
AAHX01026092
AC095852
CH474005
EDL96675
EDL96676
EDL96677
EDL96678
EDL96679
EDL96680
EDL96681
AF130457
AAD24180
AF157016
AAF80335
DQ120509
AAZ23848
DQ120510
AAZ23849
Q9WUD9
XM_011529014
XP_011527316
NC_018931
AMYH02037046
K03212
K03213
K03214
K03215
K03216
K03217
K03218
M16237
M16243
M16244
M16245
EU831426
ACE87113
EU831519
ACE86438
JF432365
ADZ15582
XM_006499067
XP_006499130
AC_000024
AAHY01012248
AAHY01012249
BC039953
AAH39953
XM_008762389
XP_008760611
AC_000152
ABBA01006617
ABBA01006618
ABBA01006619
XM_006499064
XP_006499127
XM_006235382
XP_006235444
XM_006235386
XP_006235448
XM_006235383
XP_006235445
XM_006235388
XP_006235450
XM_006235387
XP_006235449
XM_006235380
XP_006235442
XM_006235384
XP_006235446
XM_006235381
XP_006235443
XM_006235385
XP_006235447
AABR06027223
AABR06027224
CAC10573
CAC34523
CAM16140
CAM16141
NT_011362
NW_927339
NW_001838665
AC_000063
Q71UK5
Q9H7V3
NT_039207
NW_001030712
Q2M4I4
Q3UKD6
Q80XU2
NW_001084817
NW_047659
Q45QJ2
Q9JJ10
Q76P87
BG868120
CAI22921
NW_000179
123797574
4574719
71089987
71089989
8134704
81868594
8885998
123792899
123794673
125715
201057
25059027
62635494
74222098
81873417
AW259666
10436623
10635153
119596470
119596472
119596473
125711
13374724
15079460
1848077
338460
3406615
55930980
74712826
74749849
74761511
NT_086910
NC_007311
NW_001493161
XM_615852
XP_615852
123912696
49609372
82086043
94574472
AAI16545
AJ620750
BC116544
BX548066
CAF06181
NC_007134
NM_001003837
NP_001003837
NW_001512591
Q1JPZ3
Q6EWH0
119596468
119596469
119596471
123219085
123219086
148674287
149043101
149043102
149043103
149043104
149043105
149043106
149043107
99028937
126007504
34582248
99028938
325084
Dr.2731
ZDB-GENE-030131-3809
dre:325084

Swiss-Prot ID SRC_HUMAN
SRC_MOUSE
SRC_RAT
Q2M4I4_MOUSE
Q9JJ10_RAT
Q80XU2_MOUSE

Cell Localization Cell membrane
Mitochondrion inner membrane
Nucleus
Cytoplasm
Cytoskeleton
Perinuclear region
Cytoplasm, cytoskeleton

Ensembl ID ENSG00000197122
ENSP00000362680.2
ENST00000373578.6
ENSP00000362659.2
ENST00000373558.2
ENSMUSG00000027646
ENSMUSP00000029175.7
ENSMUST00000029175.13
ENSMUSP00000090237.4
ENSMUST00000092576.10
ENSRNOG00000009495
ENSRNOP00000071837.1
ENSRNOT00000080516.1
ENSRNOP00000012739.2
ENSRNOT00000012739.4
ENSP00000362680
ENST00000373578
ENSP00000350941
ENST00000358208
ENSMUSP00000029175
ENSMUST00000029175
ENSMUSP00000090237
ENSMUST00000092576
ENSRNOP00000071837
ENSRNOT00000080516
ENSRNOP00000012739
ENSRNOT00000012739
ENSP00000408503
ENST00000445403

MGI ID MGI:98397
98397
2139334

RGD ID 620795

TCDB ID 8.A.23.1.12

Unigene ID Hs.195659
Mm.22845
Rn.112600
Bt.61976
Dr.2731

Homologene ID 21120

Shape Sickle-vertex

IPI ID IPI00222801
IPI00328867
IPI00641230
IPI00719950
IPI00200886
IPI00620622

Microarray ID 99388_at

Homo sapiens Chromosome position 20q12-q13

Ensembl Transcript ID ENST00000358208
ENST00000373578
ENST00000373567

FunctionalClass kinase
protein C-terminus binding
protein binding
protein kinase
protein serine/threonine kinase
protein-tyrosine kinase
ATP binding
nucleotide binding
transferase
SH2 domain binding
SH3/SH2 adaptor

Bos taurus Chromosome position 13

Mus musculus Chromosome position 2 89.0 cM
2

KEGG pathway Adherens junction
ErbB signaling pathway
Focal adhesion
Gap junction
GnRH signaling pathway
Tight junction
VEGF signaling pathway

Rattus norvegicus Chromosome position 3q42

Ensembl Gene ID ENSG00000197122

LocatorString pmquery:egfr+transactivation