Supplementary 2: association of TAARs expression in breast carcinoma with disease outcome
Here, the analysis of survival for patients described in the GSE20685 dataset is summarized. We applied the threshold log2 expression = 5.0 to classify tumor samples as TAAR-positive or TAAR-negative for each TAAR gene expression. Time is represented in years.
Association of TAARs expression and overall survival
##
## Pairwise comparisons using Log-Rank test
##
## data: KM and TAAR1exp + treatment
##
## TAAR1exp=Negative, treatment=Chemo
## TAAR1exp=Negative, treatment=Hormonal 0.31
## TAAR1exp=Positive, treatment=Chemo 0.42
## TAAR1exp=Positive, treatment=Hormonal 0.31
## TAAR1exp=Negative, treatment=Hormonal
## TAAR1exp=Negative, treatment=Hormonal -
## TAAR1exp=Positive, treatment=Chemo 0.27
## TAAR1exp=Positive, treatment=Hormonal 0.77
## TAAR1exp=Positive, treatment=Chemo
## TAAR1exp=Negative, treatment=Hormonal -
## TAAR1exp=Positive, treatment=Chemo -
## TAAR1exp=Positive, treatment=Hormonal 0.27
##
## P value adjustment method: BH
##
## Pairwise comparisons using Log-Rank test
##
## data: KM and TAAR2exp + treatment
##
## TAAR2exp=Negative, treatment=Chemo
## TAAR2exp=Negative, treatment=Hormonal 0.38
## TAAR2exp=Positive, treatment=Chemo 0.50
## TAAR2exp=Positive, treatment=Hormonal 0.38
## TAAR2exp=Negative, treatment=Hormonal
## TAAR2exp=Negative, treatment=Hormonal -
## TAAR2exp=Positive, treatment=Chemo 0.38
## TAAR2exp=Positive, treatment=Hormonal 0.92
## TAAR2exp=Positive, treatment=Chemo
## TAAR2exp=Negative, treatment=Hormonal -
## TAAR2exp=Positive, treatment=Chemo -
## TAAR2exp=Positive, treatment=Hormonal 0.38
##
## P value adjustment method: BH
##
## Pairwise comparisons using Log-Rank test
##
## data: KM and TAAR5exp + treatment
##
## TAAR5exp=Negative, treatment=Chemo
## TAAR5exp=Negative, treatment=Hormonal 0.25
## TAAR5exp=Positive, treatment=Chemo 0.98
## TAAR5exp=Positive, treatment=Hormonal 0.82
## TAAR5exp=Negative, treatment=Hormonal
## TAAR5exp=Negative, treatment=Hormonal -
## TAAR5exp=Positive, treatment=Chemo 0.25
## TAAR5exp=Positive, treatment=Hormonal 0.98
## TAAR5exp=Positive, treatment=Chemo
## TAAR5exp=Negative, treatment=Hormonal -
## TAAR5exp=Positive, treatment=Chemo -
## TAAR5exp=Positive, treatment=Hormonal 0.82
##
## P value adjustment method: BH
##
## Pairwise comparisons using Log-Rank test
##
## data: KM and TAAR8exp + treatment
##
## TAAR8exp=Negative, treatment=Chemo
## TAAR8exp=Negative, treatment=Hormonal 0.26
## TAAR8exp=Positive, treatment=Chemo 0.78
## TAAR8exp=Positive, treatment=Hormonal 0.26
## TAAR8exp=Negative, treatment=Hormonal
## TAAR8exp=Negative, treatment=Hormonal -
## TAAR8exp=Positive, treatment=Chemo 0.26
## TAAR8exp=Positive, treatment=Hormonal 0.59
## TAAR8exp=Positive, treatment=Chemo
## TAAR8exp=Negative, treatment=Hormonal -
## TAAR8exp=Positive, treatment=Chemo -
## TAAR8exp=Positive, treatment=Hormonal 0.26
##
## P value adjustment method: BH
##
## Pairwise comparisons using Log-Rank test
##
## data: KM and TAAR9exp + treatment
##
## TAAR9exp=Negative, treatment=Chemo
## TAAR9exp=Negative, treatment=Hormonal 0.65
## TAAR9exp=Positive, treatment=Chemo 0.82
## TAAR9exp=Positive, treatment=Hormonal 0.42
## TAAR9exp=Negative, treatment=Hormonal
## TAAR9exp=Negative, treatment=Hormonal -
## TAAR9exp=Positive, treatment=Chemo 0.48
## TAAR9exp=Positive, treatment=Hormonal 0.67
## TAAR9exp=Positive, treatment=Chemo
## TAAR9exp=Negative, treatment=Hormonal -
## TAAR9exp=Positive, treatment=Chemo -
## TAAR9exp=Positive, treatment=Hormonal 0.42
##
## P value adjustment method: BHAssociation of TAARs expression and recurrence-free survival
##
## Pairwise comparisons using Log-Rank test
##
## data: KM and TAAR1exp + treatment
##
## TAAR1exp=Negative, treatment=Chemo
## TAAR1exp=Negative, treatment=Hormonal 0.12
## TAAR1exp=Positive, treatment=Chemo 0.93
## TAAR1exp=Positive, treatment=Hormonal 0.76
## TAAR1exp=Negative, treatment=Hormonal
## TAAR1exp=Negative, treatment=Hormonal -
## TAAR1exp=Positive, treatment=Chemo 0.12
## TAAR1exp=Positive, treatment=Hormonal 0.63
## TAAR1exp=Positive, treatment=Chemo
## TAAR1exp=Negative, treatment=Hormonal -
## TAAR1exp=Positive, treatment=Chemo -
## TAAR1exp=Positive, treatment=Hormonal 0.76
##
## P value adjustment method: BH
##
## Pairwise comparisons using Log-Rank test
##
## data: KM and TAAR2exp + treatment
##
## TAAR2exp=Negative, treatment=Chemo
## TAAR2exp=Negative, treatment=Hormonal 0.34
## TAAR2exp=Positive, treatment=Chemo 0.41
## TAAR2exp=Positive, treatment=Hormonal 0.38
## TAAR2exp=Negative, treatment=Hormonal
## TAAR2exp=Negative, treatment=Hormonal -
## TAAR2exp=Positive, treatment=Chemo 0.37
## TAAR2exp=Positive, treatment=Hormonal 0.38
## TAAR2exp=Positive, treatment=Chemo
## TAAR2exp=Negative, treatment=Hormonal -
## TAAR2exp=Positive, treatment=Chemo -
## TAAR2exp=Positive, treatment=Hormonal 0.38
##
## P value adjustment method: BH
## Warning in pchisq(chi, df, lower.tail = FALSE): NaNs produced##
## Pairwise comparisons using Log-Rank test
##
## data: KM and TAAR5exp + treatment
##
## TAAR5exp=Negative, treatment=Chemo
## TAAR5exp=Negative, treatment=Hormonal 0.20
## TAAR5exp=Positive, treatment=Chemo 0.20
## TAAR5exp=Positive, treatment=Hormonal 0.65
## TAAR5exp=Negative, treatment=Hormonal
## TAAR5exp=Negative, treatment=Hormonal -
## TAAR5exp=Positive, treatment=Chemo 0.72
## TAAR5exp=Positive, treatment=Hormonal 1.00
## TAAR5exp=Positive, treatment=Chemo
## TAAR5exp=Negative, treatment=Hormonal -
## TAAR5exp=Positive, treatment=Chemo -
## TAAR5exp=Positive, treatment=Hormonal 1.00
##
## P value adjustment method: BH
##
## Pairwise comparisons using Log-Rank test
##
## data: KM and TAAR8exp + treatment
##
## TAAR8exp=Negative, treatment=Chemo
## TAAR8exp=Negative, treatment=Hormonal 0.41
## TAAR8exp=Positive, treatment=Chemo 0.82
## TAAR8exp=Positive, treatment=Hormonal 0.41
## TAAR8exp=Negative, treatment=Hormonal
## TAAR8exp=Negative, treatment=Hormonal -
## TAAR8exp=Positive, treatment=Chemo 0.41
## TAAR8exp=Positive, treatment=Hormonal 1.00
## TAAR8exp=Positive, treatment=Chemo
## TAAR8exp=Negative, treatment=Hormonal -
## TAAR8exp=Positive, treatment=Chemo -
## TAAR8exp=Positive, treatment=Hormonal 0.41
##
## P value adjustment method: BH
##
## Pairwise comparisons using Log-Rank test
##
## data: KM and TAAR9exp + treatment
##
## TAAR9exp=Negative, treatment=Chemo
## TAAR9exp=Negative, treatment=Hormonal 0.85
## TAAR9exp=Positive, treatment=Chemo 0.85
## TAAR9exp=Positive, treatment=Hormonal 0.21
## TAAR9exp=Negative, treatment=Hormonal
## TAAR9exp=Negative, treatment=Hormonal -
## TAAR9exp=Positive, treatment=Chemo 0.85
## TAAR9exp=Positive, treatment=Hormonal 1.00
## TAAR9exp=Positive, treatment=Chemo
## TAAR9exp=Negative, treatment=Hormonal -
## TAAR9exp=Positive, treatment=Chemo -
## TAAR9exp=Positive, treatment=Hormonal 0.13
##
## P value adjustment method: BHAssociation of TAARs expression and metastases-free survival
##
## Pairwise comparisons using Log-Rank test
##
## data: KM and TAAR1exp + treatment
##
## TAAR1exp=Negative, treatment=Chemo
## TAAR1exp=Negative, treatment=Hormonal 0.027
## TAAR1exp=Positive, treatment=Chemo 0.827
## TAAR1exp=Positive, treatment=Hormonal 0.102
## TAAR1exp=Negative, treatment=Hormonal
## TAAR1exp=Negative, treatment=Hormonal -
## TAAR1exp=Positive, treatment=Chemo 0.027
## TAAR1exp=Positive, treatment=Hormonal 0.827
## TAAR1exp=Positive, treatment=Chemo
## TAAR1exp=Negative, treatment=Hormonal -
## TAAR1exp=Positive, treatment=Chemo -
## TAAR1exp=Positive, treatment=Hormonal 0.071
##
## P value adjustment method: BH
##
## Pairwise comparisons using Log-Rank test
##
## data: KM and TAAR2exp + treatment
##
## TAAR2exp=Negative, treatment=Chemo
## TAAR2exp=Negative, treatment=Hormonal 0.187
## TAAR2exp=Positive, treatment=Chemo 0.356
## TAAR2exp=Positive, treatment=Hormonal 0.028
## TAAR2exp=Negative, treatment=Hormonal
## TAAR2exp=Negative, treatment=Hormonal -
## TAAR2exp=Positive, treatment=Chemo 0.141
## TAAR2exp=Positive, treatment=Hormonal 0.187
## TAAR2exp=Positive, treatment=Chemo
## TAAR2exp=Negative, treatment=Hormonal -
## TAAR2exp=Positive, treatment=Chemo -
## TAAR2exp=Positive, treatment=Hormonal 0.018
##
## P value adjustment method: BH
##
## Pairwise comparisons using Log-Rank test
##
## data: KM and TAAR5exp + treatment
##
## TAAR5exp=Negative, treatment=Chemo
## TAAR5exp=Negative, treatment=Hormonal 0.0051
## TAAR5exp=Positive, treatment=Chemo 0.5385
## TAAR5exp=Positive, treatment=Hormonal 0.5385
## TAAR5exp=Negative, treatment=Hormonal
## TAAR5exp=Negative, treatment=Hormonal -
## TAAR5exp=Positive, treatment=Chemo 0.0051
## TAAR5exp=Positive, treatment=Hormonal 0.5385
## TAAR5exp=Positive, treatment=Chemo
## TAAR5exp=Negative, treatment=Hormonal -
## TAAR5exp=Positive, treatment=Chemo -
## TAAR5exp=Positive, treatment=Hormonal 0.5385
##
## P value adjustment method: BH
##
## Pairwise comparisons using Log-Rank test
##
## data: KM and TAAR8exp + treatment
##
## TAAR8exp=Negative, treatment=Chemo
## TAAR8exp=Negative, treatment=Hormonal 0.019
## TAAR8exp=Positive, treatment=Chemo 0.917
## TAAR8exp=Positive, treatment=Hormonal 0.236
## TAAR8exp=Negative, treatment=Hormonal
## TAAR8exp=Negative, treatment=Hormonal -
## TAAR8exp=Positive, treatment=Chemo 0.024
## TAAR8exp=Positive, treatment=Hormonal 0.917
## TAAR8exp=Positive, treatment=Chemo
## TAAR8exp=Negative, treatment=Hormonal -
## TAAR8exp=Positive, treatment=Chemo -
## TAAR8exp=Positive, treatment=Hormonal 0.293
##
## P value adjustment method: BH
##
## Pairwise comparisons using Log-Rank test
##
## data: KM and TAAR9exp + treatment
##
## TAAR9exp=Negative, treatment=Chemo
## TAAR9exp=Negative, treatment=Hormonal 0.244
## TAAR9exp=Positive, treatment=Chemo 0.853
## TAAR9exp=Positive, treatment=Hormonal 0.035
## TAAR9exp=Negative, treatment=Hormonal
## TAAR9exp=Negative, treatment=Hormonal -
## TAAR9exp=Positive, treatment=Chemo 0.244
## TAAR9exp=Positive, treatment=Hormonal 0.853
## TAAR9exp=Positive, treatment=Chemo
## TAAR9exp=Negative, treatment=Hormonal -
## TAAR9exp=Positive, treatment=Chemo -
## TAAR9exp=Positive, treatment=Hormonal 0.015
##
## P value adjustment method: BH