We are delighted to share some of the feature papers from the “Metabolomic Profiling Technology” section that were published in Metabolites (ISSN: 2218-1989) in 2024 and 2025. Many of the papers are from our Editorial Board Members and Guest Editors; they are expected to attract readers’ interest and provide valuable opportunities for follow-up research. 

The following is a list of articles that we believe will be of interest to you:

1. “Revolutionizing Blood Collection: Innovations, Applications, and the Potential of Microsampling Technologies for Monitoring Metabolites and Lipids”
by Eleonora Bossi, Elena Limo, Lisa Pagani, Nicole Monza, Simone Serrao, Vanna Denti, Giuseppe Astarita and Giuseppe Paglia
Metabolites 2024, 14(1), 46; https://doi.org/10.3390/metabo14010046
Available online: https://www.mdpi.com/2218-1989/14/1/46

2. “Peripheral Lipid Signatures, Metabolic Dysfunction, and Pathophysiology in Schizophrenia Spectrum Disorders”
by Sally Wu, Kristoffer J. Panganiban, Jiwon Lee, Dan Li, Emily C.C. Smith, Kateryna Maksyutynska, Bailey Humber, Tariq Ahmed, Sri Mahavir Agarwal, Kristen Ward et al.
Metabolites 2024, 14(9), 475; https://doi.org/10.3390/metabo14090475
Available online: https://www.mdpi.com/2218-1989/14/9/475

3. “Clinical Efficacy and Metabolomics Modifications Induced by Polyphenol Compound Supplementation in the Treatment of Residual Dizziness following Semont Maneuver in Benign Paroxysmal Positional Vertigo (BPPV) of the Posterior Semicircular Canal (PSC): Preliminary Results”
by Augusto Pietro Casani, Roberto Albera, Cristina Piras, Andrea Albera, Antonio Noto, Nicola Ducci, Luigi Atzori, Sergio Lucisano, Michele Mussap and Vassilios Fanos
Metabolites 2024, 14(2), 86; https://doi.org/10.3390/metabo14020086
Available online: https://www.mdpi.com/2218-1989/14/2/86

4. “Direct Infusion Mass Spectrometry to Rapidly Map Metabolic Flux of Substrates Labeled with Stable Isotopes”
by Nils W. F. Meijer, Susan Zwakenberg, Johan Gerrits, Denise Westland, Arif I. Ardisasmita, Sabine A. Fuchs, Nanda M. Verhoeven-Duif, Judith J. M. Jans and Fried J. T. Zwartkruis
Metabolites 2024, 14(5), 246; https://doi.org/10.3390/metabo14050246
Available online: https://www.mdpi.com/2218-1989/14/5/246

5. “Blood Metabolic Biomarkers of Diabetes Mellitus Type 2 in Aged Adults Determined by a UPLC-MS Metabolomic Approach”
by Nils W. F. Meijer, Susan Zwakenberg, Johan Gerrits, Denise Westland, Arif I. Ardisasmita, Sabine A. Fuchs, Nanda M. Verhoeven-Duif, Judith J. M. Jans and Fried J. T. Zwartkruis
Metabolites 2025, 15(6), 395; https://doi.org/10.3390/metabo15060395
Available online: https://www.mdpi.com/2218-1989/15/6/395

6. “Chemical Informatics Combined with Kendrick Mass Analysis to Enhance Annotation and Identify Pathways in Soybean Metabolomics”
by Troy D. Wood, Erin R. Tiede, Alexandra M. Izydorczak, Kevin J. Zemaitis, Heng Ye and Henry T. Nguyen
Metabolites 2025, 15(2), 73; https://doi.org/10.3390/metabo15020073
Available online: https://www.mdpi.com/2218-1989/15/2/73

7. “Spatially Resolved Plant Metabolomics”
by Ronald J. Myers, Jr., Zachary M. Tretter, Abigail G. Daffron, Eric X. Fritschi, William Thives Santos, Maiya L. Foster, Matthew Klotz, Kristin M. Stafford, Christina Kasch, Thomas J. Taylor et al.
Metabolites 2025, 15(8), 539; https://doi.org/10.3390/metabo15080539
Available online: https://www.mdpi.com/2218-1989/15/8/539

8. “LC-MS/MS Detection of Tryptophan, Kynurenine, Kynurenic Acid, and Quinolinic Acid in Urine Samples from Drug-Positive and Illicit Drug-Negative Patients with a Known History of Substance Use Disorder”
by Lindsey Contella, Christopher L. Farrell, Luigi Boccuto, Alain H. Litwin, Hunter Flanagan, Stacy E. F. Melanson, Nicole V. Tolan, Marion L. Snyder and Dina N. Greene
Metabolites 2025, 15(11), 749; https://doi.org/10.3390/metabo15110749
Available online: https://www.mdpi.com/2218-1989/15/11/749

If you are an active researcher in the field and are passionate about participating in cutting-edge research publications, please do not hesitate to contact the Metabolites Editorial Office (metabolites@mdpi.com).