Sheet Barrier and Intubating Stylet

Deﬁnition: Coronavirus disease 2019 (COVID-19), a respiratory syndrome caused by SARS-CoV-2, can be transmitted through respiratory droplets and aerosols of droplet nuclei. Aerosol-generating medical procedures (AGMP) are needed to take care of critically ill patients but place health care providers at risk of infection. With limited supplies of personal protective equipment (PPE), barrier systems were developed to help protect health care providers during tracheal intubation. The video intubating stylet shows promise to become the preferred intubation device in conjunction with plastic sheet barriers during the COVID-19 pandemic.


Introduction
Since the first case of viral pneumonia was reported from Wuhan, China in late December of 2019, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative pathogen for the Coronavirus disease 2019 (COVID-19) pandemic, has run rampant across the world [1]. As of 30 September 2021, there have been 232,636,622 confirmed cases and 4,762,089 COVID deaths [2]. As cases grew at an alarmingly exponential rate, it was quickly identified that COVID-19 could be transmitted through respiratory droplets and even through the aerosolization of droplet nuclei [3,4]. Because of the pathology and progression of the disease towards respiratory failure, aerosol-generating medical procedures (AGMP) such as laryngoscopy, endotracheal intubation and extubation, tracheostomy, bronchoscopy and bronchoalveolar lavage, positive pressure ventilation, cardiopulmonary resuscitation with bag-valve-mask, suctioning, and nasopharyngeal aspiration and washing would be necessary to take care of patients with COVID-19 infection [5]. Healthcare providers in the fields of anesthesiology, critical care medicine, emergency medicine, and otolaryngology, because of their roles in performing AGMPs for these patients, found themselves at risk of infection.

The Development of Barrier Systems
Personal protective equipment (PPE) is the primary basis for prevention of infection to healthcare workers while performing their tasks. Necessary PPE during the COVID-19 pandemic includes medical-grade masks, respirators, goggles, eye shields, face shields, gowns, gloves, shoe coverings, and head coverings [6] (Figure 1). Strict donning and doffing procedures are necessary to avoid accidental contamination of other work areas and the transmission to other patients and staff in the hospital [7]. It was quickly realized that there were not sufficient stores of PPE to safely allow healthcare providers to perform daily patient care during the pandemic [8]. Industry had a hard time ramping up production in a timely manner, and global disparities existed and have continued to exist. Without adequate PPE, coupled with other factors such as a lack of available testing, especially during the early stages of the pandemic [9], the growing number of confirmed and suspected Without adequate PPE, health care professionals quickly looked to alternative means of protection against viral transmission. One strategy was the use of a transparent physical barriers. The first reported model was designed by a Taiwanese anesthesiologist who constructed a transparent four-sided box made of plexiglass that was placed between the patient and the airway manager during tracheal intubation [12] (Figure 2A). The plans for this structure were quickly shared on social media [13], and Canneli et al. were the first to report on its use in the scientific literature [14]. Subsequently, after this idea was promoted by news and social media and the device was proliferated and distributed to some users, multiple variations of barrier devices were introduced [15][16][17][18][19][20][21]. These barriers were applied not just for endotracheal intubation and airway management ( Figure 2B,C) but were utilized in various aspects of medical care, as well as applied to facilitate other forms of human interaction during the pandemic (Figure 3). On 1 May 2020, the United States Food and Drug Administration (FDA) issued an emergency use authorization (EUA) for protective barrier enclosures [22]. Over time, three general device types were identified: (1) rigid transparent box, (2) plastic sheet with frame, and (3) plastic sheet without frame ( Figure 2). Without adequate PPE, health care professionals quickly looked to alternative means of protection against viral transmission. One strategy was the use of a transparent physical barriers. The first reported model was designed by a Taiwanese anesthesiologist who constructed a transparent four-sided box made of plexiglass that was placed between the patient and the airway manager during tracheal intubation [12] (Figure 2A). The plans for this structure were quickly shared on social media [13], and Canneli et al. were the first to report on its use in the scientific literature [14]. Subsequently, after this idea was promoted by news and social media and the device was proliferated and distributed to some users, multiple variations of barrier devices were introduced [15][16][17][18][19][20][21]. These barriers were applied not just for endotracheal intubation and airway management ( Figure 2B,C) but were utilized in various aspects of medical care, as well as applied to facilitate other forms of human interaction during the pandemic (Figure 3). On 1 May 2020, the United States Food and Drug Administration (FDA) issued an emergency use authorization (EUA) for protective barrier enclosures [22]. Over time, three general device types were identified: (1) rigid transparent box, (2) plastic sheet with frame, and (3) plastic sheet without frame (Figure 2).  Meanwhile, some airway management experts expressed their serious concerns on such a MacGyverism-style improvised medical device (e.g., the "aerosol box") and argued about the untested effectiveness and safety issues of this EUA device [23][24][25][26][27]. The main  Meanwhile, some airway management experts expressed their serious concerns on such a MacGyverism-style improvised medical device (e.g., the "aerosol box") and argued about the untested effectiveness and safety issues of this EUA device [23][24][25][26][27]. The main Meanwhile, some airway management experts expressed their serious concerns on such a MacGyverism-style improvised medical device (e.g., the "aerosol box") and argued about the untested effectiveness and safety issues of this EUA device [23][24][25][26][27]. The main concerns raised against such physical barrier enclosure include the following: (1) restriction of hand movement of the intubator and assistants; (2) heavy and bulky plexiglass is difficult to carry and position or reposition in emergency situations; (3) limited for certain body habitus and positions; (4) confined space for airway maneuvering; (5) ergonomically difficult to manipulate airway equipment; (6) introducing other new risks of cross-contamination during the use, disinfection, and disposal processes; (7) increases the cognitive load of the staff and the risk of subsequent contamination; and (8) breaches in PPE due to a tear cut by the box edge. Some pointed out that such an unvalidated box design does not reduce risks (of being infected) and probably has unintended safety consequences to the airway managers, medical staff, and the patients.

Tracheal Intubation during the COVID-19 Pandemic
Tracheal or endotracheal intubation, the process of placing a breathing tube in the patient's airway in order to maintain patency of the airway and provide oxygenation and ventilation, is often necessary in patients with critical respiratory illness [28]. Traditionally, the intubation process involves manipulating the head and neck to align the oral, laryngeal, and pharyngeal axes, the placement of a laryngoscope into the oropharynx to retract the tongue and soft tissues of the mouth, and the introduction of an endotracheal tube (ETT), loaded onto a stylet, past the glottic opening [29]. This procedure can be performed by a single operator, but an assistant often helps with the optimization of patient positioning such as jaw lift and lip retraction, handing the ETT-mounted stylet to the intubator, removing the stylet after the ETT has passed the vocal cords, and/or inflating the cuff of the endotracheal tube.
The intubation process places the healthcare professional at risk for COVID-19 infection as during traditional direct laryngoscopy, the anesthesia provider may need to be very close to the patient's mouth in order to obtain a view of the glottis to advance the ETT (Figures 2 and 4A). During the COVID-19 pandemic, it was subsequently recommended that videolaryngoscopy be preferentially utilized for tracheal intubation [5,30,31]. The technology behind a videolaryngoscope is that a camera is placed at the tip of the device, which is projected to a monitor, either mounted on the device itself or on an independent stand. The airway manager is able to obtain a view of the patient's airway and guide the ETT through the patient's glottis without placing his or her face in close proximity to the patient's airway ( Figure 4B). A recent Cochrane review had concluded that videolaryngoscopy may improve the success of tracheal intubation in adult patients, especially in difficult airways situations [32]. However, it should be noted that because of the significant increased costs of a videolaryngoscope, this device may not be available in every setting across the world.
There are many videolaryngoscopes on the market today, with regional preferences in a range of designs and costs. A subset of the videolaryngoscope is the video intubating stylet. This device is a rigid or semi-rigid stylet equipped with a camera at the tip projecting to a separate monitor ( Figures 5 and 6). The ETT is mounted onto the video stylet in a similar fashion to a traditional stylet. The tip of the stylet may be designed to be malleable and anteflex. Because the camera resides within the stylet as opposed to on a separate videoscope, a laryngoscope is not necessary to perform endotracheal intubation (Figures 6 and 7). "To see is to intubate" and "to see is to believe" are the mottos of the design of a video-assisted intubating stylet, a pioneering work that could change the face of airway management [33]. There are many videolaryngoscopes on the market today, with regional preferences in a range of designs and costs. A subset of the videolaryngoscope is the video intubating stylet. This device is a rigid or semi-rigid stylet equipped with a camera at the tip projecting to a separate monitor ( Figures 5 and 6). The ETT is mounted onto the video stylet in a similar fashion to a traditional stylet. The tip of the stylet may be designed to be malleable and anteflex. Because the camera resides within the stylet as opposed to on a separate videoscope, a laryngoscope is not necessary to perform endotracheal intubation ( Figures  6 and 7). "To see is to intubate" and "to see is to believe" are the mottos of the design of a video-assisted intubating stylet, a pioneering work that could change the face of airway management [33].
. Prevalence of using video intubating stylet technique for tracheal intubation in Taiwan. (A) Department of An-  There are many videolaryngoscopes on the market today, with regional preferences in a range of designs and costs. A subset of the videolaryngoscope is the video intubating stylet. This device is a rigid or semi-rigid stylet equipped with a camera at the tip projecting to a separate monitor ( Figures 5 and 6). The ETT is mounted onto the video stylet in a similar fashion to a traditional stylet. The tip of the stylet may be designed to be malleable and anteflex. Because the camera resides within the stylet as opposed to on a separate videoscope, a laryngoscope is not necessary to perform endotracheal intubation ( Figures  6 and 7). "To see is to intubate" and "to see is to believe" are the mottos of the design of a video-assisted intubating stylet, a pioneering work that could change the face of airway management [33].  pital is a tertiary medical center in the east coast of Taiwan. There are 1110 beds, 1788 personnel, 20 operation 3 attending anesthesiologists, and 45 certified registered nurse anesthetists. The COVID-19 outbreak and panarted since December 2020.

Combining Barrier Systems with the Video Intubating Styletd
When incorporating a barrier system with the video stylet, the length of the intubating stylet precludes its use within a rigid barrier box (Figure 8), unless the box is drasti- A potential benefit of the intubating stylet is that it may be a more economical alternative to the videolaryngoscope. In addition, many videolaryngoscopes utilize disposal laryngoscope tips/blades, which can minimize infection but are also recurring costs. Other potential benefits of the intubating stylet include a small profile, which results in less overall patient airway manipulation, such as less opening of the mouth and less lifting of the tongue. Because of its slim profile, the video stylet is more easily sanitized compared to other videolaryngoscopes. Even prior to the COVID-19 pandemic, at many institutions, the video intubating stylet had become the preferred modality for performing tracheal intubation [34][35][36][37]. Table 1 and Figure 5 show examples of high use coverage of videoassisted intubating stylets in the departments of anesthesia in Taiwan. Moreover, among 24 medical centers in Taiwan, the departments of anesthesia in 20 of them are equipped with video-assisted intubating stylets.

(91.4%)
This hospital is a tertiary medical center in the east coast of Taiwan. There are 1110 beds, 1788 personnel, 20 operation rooms, 13 attending anesthesiologists, and 45 certified registered nurse anesthetists. The COVID-19 outbreak and pandemic started since December 2020.

Combining Barrier Systems with the Video Intubating Styletd
When incorporating a barrier system with the video stylet, the length of the intubating stylet precludes its use within a rigid barrier box (Figure 8), unless the box is drastically modified to accommodate the length of the intubating stylet. This may not be practical to manufacture, and the added height might also make the box difficult to handle as well as a safety concern to patients and medical staff. Additionally, the semi-rigid stylet is not long or flexible enough to be handled from outside the barrier box through the hand orifices at the head of the patient. It was quickly realized that the plastic sheet was the only barrier system that could be practically utilized with the video intubating stylet [38][39][40].
There are several ways that the plastic sheet can be utilized to protect the anesthesia provider. In its simplest unmodified form, the plastic sheet could be laid across the patient's head to function as a general barrier. The health care professional subsequently reaches under to the sheet to perform tracheal intubation ( Figure 2C). Because of its malleability and transparency, other maneuvers not involving the airway itself, such as an assistant providing jaw lift, can be performed over the sheet (Figure 9). If the plastic sheet hampers the ability of the anesthesia provider to successfully intubate the patient, the sheet can be easily and rapidly removed, as opposed to the bulkier and heavier plastic box. Table 2 summarized the advantages and disadvantages of plastic sheet barriers design and aerosol box design. Encyclopedia 2021, 1, FOR PEER REVIEW 8      Any respiratory droplets and aerosols that may have been generated during intubation will settle onto the sheet or under the sheet on the patient (Figure 10), as opposed to being dispersed into the air, and there may be less risk of contamination if the sheet is carefully folded or rolled up at the end of the procedure. Additionally, there is an option to leave the sheet over the patient's head until time of extubation, thus protecting airway managers from co-infection at the end of surgery, when the patient may cough or buck at time of emergence from anesthesia. The sheet can be removed concurrently with the endotracheal tube, and so be used to collect the dirty ETT for disposal. In fact, one of the first suggested uses for the plastic sheet was not for tracheal intubation but for minimizing droplet spray during extubation [41].
Encyclopedia 2021, 1, FOR PEER REVIEW 10 to leave the sheet over the patient's head until time of extubation, thus protecting airway managers from co-infection at the end of surgery, when the patient may cough or buck at time of emergence from anesthesia. The sheet can be removed concurrently with the endotracheal tube, and so be used to collect the dirty ETT for disposal. In fact, one of the first suggested uses for the plastic sheet was not for tracheal intubation but for minimizing droplet spray during extubation [41]. A negative aspect of simply reaching under the sheet to perform airway maneuvers is the contamination of the healthcare professional's hands and arms during the procedure. In addition, the visualization of the indirect monitor may be difficult if the screen is mounted on the videoscope itself [42]. Subsequently, plastic sheets were modified by making openings in the plastic sheet, allowing for the airway device and ETT to be passed from above the sheet or for the provider's hands to reach through [17,20] (Figures 9 and  11). Even if the monitor was affixed to the videoscope, the operator would still have an unobstructed view if the screen remained above the barrier. In order to use a videolaryngoscope with this modified plastic sheet method, either a single large opening would be made to accommodate both laryngoscope and endotracheal tube, or two smaller openings could be made in close proximity to one another. However, the larger the opening that was created into the sheet, the larger the risk for environmental contamination, defeating the purpose of using a barrier system. A negative aspect of simply reaching under the sheet to perform airway maneuvers is the contamination of the healthcare professional's hands and arms during the procedure. In addition, the visualization of the indirect monitor may be difficult if the screen is mounted on the videoscope itself [42]. Subsequently, plastic sheets were modified by making openings in the plastic sheet, allowing for the airway device and ETT to be passed from above the sheet or for the provider's hands to reach through [17,20] (Figures 9 and 11). Even if the monitor was affixed to the videoscope, the operator would still have an unobstructed view if the screen remained above the barrier. In order to use a videolaryngoscope with this modified plastic sheet method, either a single large opening would be made to accommodate both laryngoscope and endotracheal tube, or two smaller openings could be made in close proximity to one another. However, the larger the opening that was created into the sheet, the larger the risk for environmental contamination, defeating the purpose of using a barrier system. The advantage of using the video intubating stylet with the plastic sheet is that because of its slim profile, only a single small opening would need to be made to allow the intubating stylet and mounted ETT to pass through (Figures 11 and 12). A single institution's protocol has been previously described in the literature, in which two small crosscuts were made into the plastic sheet with a surgical blade [38][39][40], (Figure 11). The purpose of the second incision was to have the ability to quickly perform mask ventilation or oral suctioning if the need arose during the intubation attempt ( Figure 13). Both crosscuts were covered with transparent adhesive film, and a large bore needle was used to pierce a hole in the transparent film, minimizing the size of the defect while still making it easy to introduce the airway apparatus. As the video stylet passed through the hole, the transparent film would enlarge to accept the stylet but would also adhere to the endotracheal tube, minimizing the defect in the plastic sheet and the subsequent risk of environmental contamination. Figure 11. Modification of plastic sheet barrier with (A) small incisions marked by colored tape to (B) allow passage of intubation device from above the sheet.
The advantage of using the video intubating stylet with the plastic sheet is that because of its slim profile, only a single small opening would need to be made to allow the intubating stylet and mounted ETT to pass through (Figures 11 and 12). A single institution's protocol has been previously described in the literature, in which two small crosscuts were made into the plastic sheet with a surgical blade [38][39][40], (Figure 11). The purpose of the second incision was to have the ability to quickly perform mask ventilation or oral suctioning if the need arose during the intubation attempt ( Figure 13). Both crosscuts were covered with transparent adhesive film, and a large bore needle was used to pierce a hole in the transparent film, minimizing the size of the defect while still making it easy to introduce the airway apparatus. As the video stylet passed through the hole, the transparent film would enlarge to accept the stylet but would also adhere to the endotracheal tube, minimizing the defect in the plastic sheet and the subsequent risk of environmental contamination.
Prefabricated plastic sheets have been produced with seam lines to allow easy removal of the plastic sheet after successful tracheal intubation (Figure 14), however, even without prefabricated sheets, a homemade sheet can be precut to facilitate its easy removal. While the plastic sheet is disposable as a medical waste, the intubating stylet is either disposable (costed from USD 50 to 100) or to be disinfected according to infection control policies and standard operating procedures adhered to local health regulations (for more detailed description, please see the reference [40]). As previously described, because the plastic sheet can also serve as protection against contamination during the extubation process, the sheet may be left over the patient's head until surgery has concluded and the ETT has been removed [17,18,41].  Prefabricated plastic sheets have been produced with seam lines to allow easy removal of the plastic sheet after successful tracheal intubation (Figure 14), however, even without prefabricated sheets, a homemade sheet can be precut to facilitate its easy removal. While the plastic sheet is disposable as a medical waste, the intubating stylet is either disposable (costed from USD 50 to 100) or to be disinfected according to infection control policies and standard operating procedures adhered to local health regulations Figure 12. Only a small crosscut in the plastic sheet is needed (marked by X) to allow advancement of the video-assisted intubating stylet.
Encyclopedia 2021, 1, FOR PEER REVIEW 12 Figure 12. Only a small crosscut in the plastic sheet is needed (marked by X) to allow advancement of the video-assisted intubating stylet. Prefabricated plastic sheets have been produced with seam lines to allow easy removal of the plastic sheet after successful tracheal intubation (Figure 14), however, even without prefabricated sheets, a homemade sheet can be precut to facilitate its easy removal. While the plastic sheet is disposable as a medical waste, the intubating stylet is either disposable (costed from USD 50 to 100) or to be disinfected according to infection control policies and standard operating procedures adhered to local health regulations  (for more detailed description, please see the reference [40]). As previously described, because the plastic sheet can also serve as protection against contamination during the extubation process, the sheet may be left over the patient's head until surgery has concluded and the ETT has been removed [17,18,41]. Figure 14. Prefabricated plastic sheet with areas marked by circles to guide creation of incisions for introduction of laryngoscope/suction catheter and video stylet/endotracheal tube, as well as seam lines to allow easy removal of the plastic sheet after intubation.

Criticisms of Barrier Methods
A recent review of the literature screened 4509 unique articles describing barrier systems and airway management, but only 123 full-text articles met the inclusion criteria [21]. Of these papers, 42% utilized a box, while 54% used a plastic sheet, further subdivided into sheets with support (32%) and without support (22%). Unfortunately, the majority of papers written on this subject have been short letters or commentaries. To date, there is not strong evidence to support the use of barrier systems, although these systems seem to have logical benefit.
Based on what has been observed and reported in the literature, a large criticism of rigid box systems has been a delay in time to intubation, with potential worsening of airway views especially in difficult intubation situations [43][44][45]. The rigid plastic structure limits the maneuvers an airway manager might perform to optimize the glottic view (Figures 2A and 8), and it might also hinder other staff from providing assistance during the intubation attempts. Other criticisms of the rigid box design have been environmental contamination at the open caudal end, as well as from secondary aerosolization at the time of box removal, difficulty with sanitation, and even harm to medical staff during its use [46]. Some studies concluded that plastic sheet systems do better than rigid box systems in terms of environmental exposure [47], operator ergonomics, and ease of allowing another provider to provide assistance [18]. Subsequently, on 20 August 2020, the FDA revoked the umbrella EUA for barrier devices and now recommends the concurrent use of negative pressure with these systems [48].
The use of the intubating stylet, although theoretically simpler and easier to use, has not been validated in humans. A few mannequin studies concluded that the intubating stylet was easier to use, had quicker intubation times with higher success rates compared Figure 14. Prefabricated plastic sheet with areas marked by circles to guide creation of incisions for introduction of laryngoscope/suction catheter and video stylet/endotracheal tube, as well as seam lines to allow easy removal of the plastic sheet after intubation.

Criticisms of Barrier Methods
A recent review of the literature screened 4509 unique articles describing barrier systems and airway management, but only 123 full-text articles met the inclusion criteria [21]. Of these papers, 42% utilized a box, while 54% used a plastic sheet, further subdivided into sheets with support (32%) and without support (22%). Unfortunately, the majority of papers written on this subject have been short letters or commentaries. To date, there is not strong evidence to support the use of barrier systems, although these systems seem to have logical benefit.
Based on what has been observed and reported in the literature, a large criticism of rigid box systems has been a delay in time to intubation, with potential worsening of airway views especially in difficult intubation situations [43][44][45]. The rigid plastic structure limits the maneuvers an airway manager might perform to optimize the glottic view (Figures 2A and 8), and it might also hinder other staff from providing assistance during the intubation attempts. Other criticisms of the rigid box design have been environmental contamination at the open caudal end, as well as from secondary aerosolization at the time of box removal, difficulty with sanitation, and even harm to medical staff during its use [46]. Some studies concluded that plastic sheet systems do better than rigid box systems in terms of environmental exposure [47], operator ergonomics, and ease of allowing another provider to provide assistance [18]. Subsequently, on 20 August 2020, the FDA revoked the umbrella EUA for barrier devices and now recommends the concurrent use of negative pressure with these systems [48].
The use of the intubating stylet, although theoretically simpler and easier to use, has not been validated in humans. A few mannequin studies concluded that the intubating stylet was easier to use, had quicker intubation times with higher success rates compared to the traditional laryngoscope in simulated difficult airways [49,50], and a small randomized trial of patients being intubated in the lateral decubitus position suggested that the time to intubation using a video stylet was shorter compared to using a fiberoptic bronchoscope, although a greater hemodynamic response and higher incidence of sore throat was observed with the intubating stylet [51]. To date, there are sparse studies comparing the use of a video intubating stylet with a videolaryngoscope, which is currently commonly accepted as the preferred difficult airway device in the majority of the world [32].
Obesity is often associated with increased neck circumference, both of which are risk factors for difficult intubation [52], and obesity has been shown to be associated with a more severe COVID-19 course, including ICU admission and increased mortality [53,54]. COVID-19 patients in critical respiratory illness have poor respiratory reserves, and time to oxygen desaturation is rapid. A concern with using the intubating stylet in the obese patient is that it may be difficult to obtain a view of the glottis if there is significant soft tissue collapse after the induction of anesthesia. In extreme situations, jaw lift may not improve visualization of the airway. A laryngoscope, which has a wide blade to retract collapsed soft tissue structures and can facilitate maneuvering of the ETT towards the glottic opening, is typically used with the intubating stylet technique.

Future Directions and Conclusions
It is worthy to mention that videolaryngoscopy became a new paradigm for tracheal intubation (e.g., unanticipated and expected difficult airway management) since decades ago [32,55]. Such critical roles and increasing prevalence of videolaryngoscopy have been emerged in many clinical environments, such as emergency rooms, operating theaters, intensive care units, and wards [56][57][58]. Among all the intubating tools, it is interesting to note that optical (lighted and video-assisted) stylets are still not prevalent in many countries so far [59]. Such kinds of optical stylets, originally designed by Shikani [33] and later modified by Levitan [60], have been evaluated in several different clinical scenarios [61][62][63][64][65][66]. The advantages of such an airway management modality are as follows: obtaining better patient glottic view with high first-pass success rates, no need to contact any airway soft tissues and therefore causing less stimulation or tissue damages, maintaining a safe distance between the intubator from patient's mouth, high learning curve, etc.
During COVID-19 pandemic, not surprisingly, the beneficial role of videolaryngoscopy has been repeatedly advocated in several guidelines [30,31]. Meanwhile, together with videolaryngoscopy, a gum elastic bougie (GEB, also named an endotracheal tube introducer) is an effective adjunct to difficult airway management [67][68][69][70][71]. Therefore, both essential tools have reasonably been proposed to be included in the COVID-19 emergency tracheal intubation kit dump and tray [30,31]. However, in the real world, videolaryngoscopes and video-assisted intubating stylets might not be available in some countries and regions. In that case, the airway managers should have adequate PPE while using conventional direct laryngoscope for tracheal intubation during COVID-19 pandemic.
Although the use of a video intubating stylet in conjunction with a plastic barrier sheet may be the most efficacious method to prevent environmental contamination from droplet and aerosol exposure during AGMPs, based upon the small size of the incision in the sheet that is necessary to pass the ETT, more research is needed in this area. Plastic sheets need to be shown that they do indeed mitigate the risk of environmental exposure and health care provider co-infection during tracheal intubation and extubation. Consensus on plastic sheet modifications can help reproducibility and improve efficacy across different clinical settings and hospital situations. More randomized trials with adequate patient enrollment is necessary to investigate the following scenarios: (1) the comparison of videolaryngoscopes to video stylets in difficult airway situations, especially in morbidly obese patients; (2) the effectiveness and safety of utilizing plastic sheet barriers during airway manipulation using a variety of intubating devices; and more specifically, (3) the comparison of videolaryngoscope to the video intubating stylet in conjunction with plastic sheet barrier systems.
Nonetheless, the video intubating stylet continues to gain acceptance as an indirect video intubating device in particular regions of the world given its ease of use, short training duration, relative cost, and straightforward re-sanitation process. Plastic barrier devices have shown promise to reduce environmental contamination and hospital personnel coinfection during AGMPs such as tracheal intubation. Because of its slim profile and minimal