Immuno, Volume 2, Issue 1
2022 March - 16 articles
Cover Story: Chronic inflammatory demyelinating polyneuropathy (CIDP) is an autoimmune-mediated inflammatory disease affecting the peripheral nerves and the nerve roots. This clinically heterogeneous neurological disorder is considered the chronic counterpart of acute Guillain–Barré syndrome. Currently available treatments are mostly empirical; they include corticosteroids, intravenous immunoglobulins, plasma exchange, and chronic immunosuppressive agents, either alone or in combination. Some of them have long-term adverse effects. Greater awareness of CIDP pathophysiological mechanisms has recently led to novel development of safer and more efficient ways of intervention in this context. This review summarizes selected preclinical and clinical findings and proposes the outlines of future directions to ameliorate the conditions of patients with CIDP. View this paper
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Immuno - ISSN 2673-5601