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Journal of Molecular Pathology, Volume 2, Issue 4

December 2021 - 5 articles

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Articles (5)

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Case Report

3,106 Views

6 Pages

Fine-Needle Aspiration Is Suitable for Breast Cancer BRCA Molecular Assessment: A Case Report

Francesco Pepe,
Pasquale Pisapia,
Gianluca Russo,
Mariantonia Nacchio,
Elena Vigliar,
Mario Giuliano,
Umberto Malapelle,
Giancarlo Troncone and
Claudio Bellevicine

J. Mol. Pathol.2021, 2(4), 319-324;https://doi.org/10.3390/jmp2040028

3 December 2021

Breast cancer is the most common cause of cancer-related deaths in the female population worldwide. To the best of our knowledge, breast cancer (BRCA)1/2 gene mutations have not been described yet on breast cancer cytological specimens. Here we descr...

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Opinion

6 Citations

4,809 Views

7 Pages

From Information Overload to Actionable Insights: Digital Solutions for Interpreting Cancer Variants from Genomic Testing

Stephanie J. Yaung and
Adeline Pek

J. Mol. Pathol.2021, 2(4), 312-318;https://doi.org/10.3390/jmp2040027

21 November 2021

Given the increase in genomic testing in routine clinical use, there is a growing need for digital technology solutions to assist pathologists, oncologists, and researchers in translating variant calls into actionable knowledge to personalize patient...

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Case Report

4,326 Views

6 Pages

Progression of Well-Differentiated Papillary Mesothelial Tumour to Mesothelioma in a Patient with Ehlers Danlos Syndrome

Sarita Prabhakaran,
Matthew Hussey,
Kenneth J. O’Byrne and
Sonja Klebe

J. Mol. Pathol.2021, 2(4), 306-311;https://doi.org/10.3390/jmp2040026

29 October 2021

Well-differentiated papillary mesothelioma has been renamed well-differentiated papillary mesothelial tumour (WDPMT) in the current WHO classification because all mesotheliomas are now regarded as malignant. WDPMT is now defined as a non-invasive pap...

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Article

4 Citations

5,287 Views

10 Pages

Conventional Transbronchial Needle Aspiration (cTBNA) and EBUS-Guided Transbronchial Needle Aspiration (EBUS-TBNA): A Retrospective Study on the Comparison of the Two Methods for Diagnostic Adequacy in Molecular Analysis

Francesca Signorini,
Martina Panozzi,
Agnese Proietti,
Greta Alì,
Olivia Fanucchi,
Alessandro Picchi,
Alessandro Ribechini,
Anello M. Poma,
Rossella Bruno and
Antonio Chella
+ 1 author

J. Mol. Pathol.2021, 2(4), 296-305;https://doi.org/10.3390/jmp2040025

9 October 2021

Introduction: In recent years, there has been a growing development of molecularly targeted therapies for various types of solid tumors—in particular, in non-small-cell lung cancer (NSCLC). This has required the need for greater quantities of tissue...

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Review

7 Citations

14,369 Views

15 Pages

Clinical and Molecular Features of Anti-CENP-B Autoantibodies

Rahul M. Prasad,
Alfonso Bellacosa and
Tim J. Yen

J. Mol. Pathol.2021, 2(4), 281-295;https://doi.org/10.3390/jmp2040024

29 September 2021

Centromeric proteins are the foundation for assembling the kinetochore, a macromolecular complex that is essential for accurate chromosome segregation during mitosis. Anti-centromere antibodies (ACAs) are polyclonal autoantibodies targeting centromer...

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