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Diabetology, Volume 6, Issue 7

2025 July - 14 articles

Cover Story: This study evaluates recruitment strategies for a community-based, medically tailored nutrition intervention targeting underserved populations with early diabetes. A participant-focused, relationship-driven approach significantly outperformed registry-based cold-calling by fostering trust and demonstrating cultural and structural competency. However, even with strong community partnerships, social determinants of health and competing life demands, such as caregiving, transportation, and work, remained barriers to engagement. Findings suggest that while community-centric engagement strategies are critical, a multifaceted, adaptable recruitment strategy is essential to effectively reach and retain underrepresented groups in chronic disease prevention efforts. View this paper
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Articles (14)

  • Article
  • Open Access
4 Citations
2,114 Views
14 Pages

Adipose Tissue Dysfunction and Hepatic Steatosis in New-Onset Diabetes

  • Emilia Rusu,
  • Mariana Jinga,
  • Raluca Cursaru,
  • Georgiana Enache,
  • Adrian Costache,
  • Ioana Verde,
  • Andra Nica,
  • Anca Alionescu,
  • Florin Rusu and
  • Gabriela Radulian

Background/Objectives: This study aimed to evaluate adipose tissue dysfunction, assessed through adipocytokines and proinflammatory cytokines, in relation to hepatic steatosis (HS) in patients with newly diagnosed type 2 diabetes (T2D). Methods: An o...

  • Article
  • Open Access
2 Citations
2,605 Views
10 Pages

Time in Tight Range in AHCL Systems: Propensity-Score-Matched Analysis of MiniMed 780G and Control-IQ

  • María Sara Tapia Sanchiz,
  • Victor Navas-Moreno,
  • Fernando Sebastián Valles,
  • Juan José Raposo López,
  • Carolina Sager La Ganga,
  • Elena Carrillo López,
  • Sara González Castañar,
  • Selma Amar,
  • Marcos Lahera Vargas and
  • Mónica Marazuela
  • + 1 author

Background: Advanced hybrid closed-loop (AHCL) systems have improved the glycemic control in type 1 diabetes (T1D). While time in range (TIR) (70–180 mg/dL) is the standard metric, time in tight range (TITR) (70–140 mg/dL) offers a strict...

  • Article
  • Open Access
1,438 Views
10 Pages

Is the Presence of a Depressive Disorder a Risk Factor for Worse Metabolic Outcomes Among Patients with Type 2 Diabetes Treated with GLP-1 Analogs?

  • Joana Nicolau,
  • Pilar Sanchís,
  • María Isabel Tamayo,
  • Guadalupe Pérez-Bec,
  • Guido Sfondrini,
  • Mireia Grimalt and
  • Lluís Masmiquel

Background/Objectives: Type 2 diabetes mellitus (T2DM) is frequently associated with depressive disorder (DD), which negatively impacts glycemic control and overall metabolic outcomes. Recent evidence suggests that glucagon-like peptide-1 receptor ag...

  • Article
  • Open Access
1 Citations
3,780 Views
19 Pages

Compare the Decrease in Visceral Adipose Tissue in People with Obesity and Prediabetes vs. Obesity and Type 2 Diabetes Treated with Liraglutide

  • Rosa Nayely Hernández-Flandes,
  • María de los Ángeles Tapia-González,
  • Liliana Hernández-Lara,
  • Eduardo Osiris Madrigal-Santillán,
  • Ángel Morales-González,
  • Liliana Aguiano-Robledo and
  • José A. Morales-González

Obesity is considered a global pandemic. In Mexico, 7/10 adults, 4/10 adolescents, and 1/3 children are overweight or obese, and it is estimated that 90% of cases of type 2 diabetes (T2D) are attributable to these pathologies. Visceral adipose tissue...

  • Brief Report
  • Open Access
3,793 Views
10 Pages

Background: Type 2 diabetes mellitus (T2DM) is common among patients with chronic obstructive pulmonary disease (COPD). We examined the association between glycemic control and clinical outcomes in patients with COPD exacerbation and T2DM. Methods: A...

  • Article
  • Open Access
2 Citations
2,347 Views
11 Pages

Background/Objectives: Hypoglycemia remains the most frequent acute complication of diabetes, particularly among insulin-treated patients, with significant implications for morbidity, length of hospital stay, and healthcare costs. Nurses play a criti...

  • Article
  • Open Access
1 Citations
5,357 Views
11 Pages

High User Satisfaction Rates with DEXCOM™ Continuous Glucose Monitoring Device in People with Type 1 Diabetes—A Pilot Cross-Sectional Study

  • Benái Paponette,
  • Laura Keaver,
  • Peter Lynch,
  • Elias Eltoum,
  • Liam Clarke,
  • Jordan Carty,
  • Siobhan Bacon and
  • Catherine McHugh

Background/Objectives: DEXCOM™ continuous glucose monitoring devices (DCGMs) have been shown to improve glycaemic control and complication rates in people with Type 1 diabetes (T1DM). However, little qualitative data exists regarding user satis...

  • Article
  • Open Access
1 Citations
1,463 Views
12 Pages

Introduction: Recent technological progress in optical imaging—such as adaptive optics, interferometry and tomography—has greatly improved the resolution of retinal imaging. The ability to capture sequential images over time is particular...

  • Article
  • Open Access
1,803 Views
14 Pages

Oral Administration of 5-Aminolevulinic Acid Does Not Ameliorate Autoimmune Diabetes in NOD Mice

  • Shinpei Nishikido,
  • Satoru Akazawa,
  • Tetsuro Niri,
  • Shin-Ichi Inoue,
  • Katsuya Matsuda,
  • Taiki Aoshi,
  • Masahiro Nakashima,
  • Ai Haraguchi,
  • Ichiro Horie and
  • Norio Abiru
  • + 3 authors

Background/Objectives: 5-Aminolevulinic acid (5-ALA) is a biosynthetic precursor of heme that induces heme oxygenase-1 (HO-1). Therapeutic induction of HO-1 has shown effectiveness in various autoimmune disease models, including type 1 diabetes (T1D)...

  • Article
  • Open Access
3,336 Views
14 Pages

5-Year Follow-Up of Advanced Therapy Use in High-Risk Diabetic Foot Ulcers

  • Margaret Doucette,
  • Stephanie Seabolt,
  • Kattie Payne and
  • Jeremy Boyd

Background/Objectives: Advanced wound healing biologics for diabetic foot ulcer (DFU) are typically withheld from persons who are at high risk for amputation. However, a prospective, single-center cohort study evaluated the use of an advanced biologi...

(This article belongs to the Special Issue Innovations in the Identification, Prevention and Management of Diabetes-Related Foot Complications)
  • Article
  • Open Access
5 Citations
4,871 Views
13 Pages

Body Roundness Index (BRI) Predicts Metabolic Syndrome in Postmenopausal Women with Obesity Better than Insulin Resistance

  • Daniel de Luis,
  • Marife Muñoz,
  • Olatz Izaola,
  • Juan José Lopez Gomez,
  • Daniel Rico and
  • David Primo

Background/Objective: The body roundness index (BRI) has emerged as a novel anthropometric parameter with potential utility in the assessment of obesity and its associated metabolic complications. This study aimed to identify the optimal BRI cut-off...

  • Article
  • Open Access
2,146 Views
16 Pages

Background/Objectives: Recruiting and retaining low-income participants in community-based diabetes interventions remains a persistent challenge, particularly in medically underserved areas. This study describes engagement strategies and lessons lear...

(This article belongs to the Special Issue Lifestyle Behavior Intervention for Diabetes Prevention and Management: 2nd Edition)
  • Review
  • Open Access
2 Citations
4,057 Views
33 Pages

Accelerated Ageing in Type 1 Diabetes: A Focus on Molecular Mechanisms Underlying Telomere Shortening

  • Miruna-Maria Apetroaei,
  • Stella Baliou,
  • Petros Ioannou,
  • Emmanouil Fandridis,
  • Andreea Letitia Arsene and
  • Aristidis Tsatsakis

Type 1 diabetes mellitus (T1D) is increasingly recognised not only as an autoimmune metabolic disorder but also as a condition associated with accelerated biological ageing. Among the hallmarks of ageing, telomere shortening has emerged as a key feat...

  • Editorial
  • Open Access
2 Citations
2,089 Views
3 Pages

Cardiorenometabolic syndrome, a constellation of interrelated risk factors including insulin resistance, central obesity, dyslipidemia, and hypertension, is rapidly becoming one of the defining global health challenges of our time [...]

(This article belongs to the Special Issue Risk of Type 2 Diabetes Mellitus: Cardiorenometabolic Syndrome and Its Components)
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Diabetology - ISSN 2673-4540