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Polysaccharides, Volume 6, Issue 1

2025 March - 23 articles

Cover Story: Polysaccharide-based hydrogels are of great interest for biomedical applications due to their inherent beneficial features. Through advanced polymer chemistry, it was possible to tailor the molecular structure of cellulose and xylan by introducing (i) reactive allyl groups and (ii) groups that modulate water solubility. Hydrogels were prepared from these derivatives by selective crosslinking via the thiol–ene reaction. This Click Chemistry approach, triggered by UV irradiation, enabled very fast yet selective hydrogel formation. Thus, it was possible to create well-defined hydrogel objects through a facile 3D printing process. View this paper
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Articles (23)

  • Article
  • Open Access
5 Citations
1,652 Views
17 Pages

Composite Based on Biomineralized Oxidized Bacterial Cellulose with Strontium Apatite for Bone Regeneration

  • Ana Lorena de Brito Soares,
  • Erika Patrícia Chagas Gomes Luz,
  • Igor Iuco Castro-Silva,
  • Rodolpho Ramilton de Castro Monteiro,
  • Fábia Karine Andrade and
  • Rodrigo Silveira Vieira

Rejections of commercial bone implants have driven research in the biomaterials field to develop more biocompatible and less cytotoxic alternatives. This study aims to create composites based on oxidized bacterial cellulose (OBC) and strontium apatit...

  • Article
  • Open Access
1,129 Views
20 Pages

This study is a comparative investigation of the activity of unloaded and curcumin-loaded oil-in-water emulsion or chitosan-based capsules on rabbit retinal cells (RRC), coronavirus HCoV-OC43, and virus HSV-1 virus in relation to their potential opht...

  • Article
  • Open Access
1 Citations
2,063 Views
18 Pages

Chondroitin Sulfate/Cyanocobalamin–Chitosan Polyelectrolyte Complexes for Improved Oral Delivery of Colistin

  • Natallia V. Dubashynskaya,
  • Andrey Y. Borovskoy,
  • Anton N. Bokatyi,
  • Tatiana S. Sall,
  • Tatiana S. Egorova,
  • Elena V. Demyanova,
  • Ekaterina A. Murashko and
  • Yury A. Skorik

Introduction. The rise of multidrug resistance in Gram-negative ESKAPE pathogens is a critical challenge for modern healthcare. Colistin (CT), a peptide antibiotic, remains a last-resort treatment for infections caused by these superbugs due to its p...

  • Article
  • Open Access
6 Citations
4,597 Views
11 Pages

Enhancing the Properties of Sodium Alginate with a Glycerol–Silicate Plasticizer

  • Anthony Fasulo,
  • Corradina Towie,
  • Lucie Mouchiroud,
  • Hamza Malik,
  • Daniel Foucher and
  • Guerino Sacripante

The impact of a glycerol–silicate (GS) plasticizer on the mechanical, thermal and hydrophobic properties pertaining to sodium alginate (NaAlg) and calcium alginate (CaAlg) films were investigated. Spectroscopic and physio-chemical analysis were...

  • Article
  • Open Access
5 Citations
3,308 Views
17 Pages

Chitosan is an attractive material for developing inks for extrusion-based bioprinting of 3D structures owing to its excellent properties, including its mechanical properties and antimicrobial activity when used in wound dressings. A key challenge in...

  • Article
  • Open Access
1 Citations
1,421 Views
12 Pages

Characterization of Heterogeneous Polysaccharides from the Aerial Parts of Clinopodium bolivianum (Benth.) with Neutralizing Activity Against HIV-1 Infection

  • Estefanía Hernández,
  • Paulina Bermejo,
  • María José Abad,
  • Manuela Beltrán,
  • José Alcamí,
  • Alicia Prieto,
  • José Antonio Guerra and
  • Luis Miguel Bedoya

Medicinal plants are widely used in Bolivian folk medicine for the treatment of infectious diseases. We have selected one, Clinopodium bolivianum (Benth.) Kuntze, known as “Khoa”, to investigate its potential anti-HIV activity since, trad...

  • Article
  • Open Access
6 Citations
2,284 Views
25 Pages

We developed bio-based chitosan–gelatin films, CHG-LO films, incorporating lavender essential oil (15–26 wt% LO) and oleic acid (33–47 wt% OA) with smooth surfaces and thicknesses of 0.42–0.99 mm. For their manufacture, the na...

  • Article
  • Open Access
1,655 Views
14 Pages

Granulometry and Functional Properties of Yuca Flour (Yucca decipiens Trel.) for Food Purposes

  • Selena R. Martínez-Betancourt,
  • Jorge Cadena-Iñiguez,
  • Gerardo Loera-Alvarado,
  • Víctor M. Ruiz-Vera,
  • Ramón Marcos Soto-Hernández,
  • Concepción López-Padilla and
  • Dalia Abigail García-Flores

Mexican yuca (Yucca decipiens Trel.) is native to the semi-desert region of north-central Mexico. Based on its medicinal uses, the flour produced from its leaves and stems was evaluated to determine new food uses. The flour was characterized based on...

  • Article
  • Open Access
1 Citations
1,645 Views
14 Pages

Owing to its natural degradability and excellent film-forming characteristics, sodium alginate (SA) is gaining growing popularity in the field of food packaging. However, the insufficient antioxidant and antibacterial properties hinder its applicatio...

  • Article
  • Open Access
2 Citations
1,706 Views
24 Pages

Pea Protein—ĸ-Carrageenan Nanoparticles for Edible Pickering Emulsions

  • Galia Hendel,
  • Noy Hen,
  • Shulamit Levenberg and
  • Havazelet Bianco-Peled

Pickering emulsions (PEs) can be utilized as inks for 3D food printing owing to their extensive stability and appropriate viscoelastic properties. This research explores food-grade PEs stabilized with nanoparticles (NPs) based on modified pea protein...

  • Article
  • Open Access
5 Citations
2,461 Views
21 Pages

Allyl-Functionalized Polysaccharides for 3D Printable Hydrogels Through Thiol–Ene Click Chemistry

  • Zakaria Atmani,
  • Tobias Steindorfer,
  • Rupert Kargl,
  • Karin Stana Kleinschek,
  • Thomas Heinze and
  • Martin Gericke

This study presents the synthesis of allyl-functionalized polysaccharide carbamates (AFCs) with tailored water solubility designed for use in responsive hydrogels and 3D printing applications. A modular one-pot approach was employed to produce cellul...

  • Article
  • Open Access
1 Citations
2,047 Views
17 Pages

Potential of Agricultural Waste Fibers for Dialdehyde Carboxymethyl Cellulose Production

  • Suthaphat Kamthai,
  • Chanakan Prom-u-thai,
  • Patompong Khaw-on,
  • Aree Deenu and
  • Kamonwan Tachai

This study investigates the environmental issue of air pollution (PM 2.5) from agricultural waste in Thailand and promotes the utilization of agricultural wastes by using their chemical compositions, especially cellulose content. The fourth readily a...

  • Review
  • Open Access
7 Citations
3,209 Views
20 Pages

Hydrophobic Chitosan Derivatives for Gene and Drug Delivery in Cancer Therapies

  • Daria N. Poshina,
  • Anna D. Rakshina and
  • Yury A. Skorik

Chitosan remains one of the most widely used biopolymers in biomedicine due to its non-toxicity and biodegradability. It is easily chemically modified, allowing its properties to be effectively altered to improve its performance as a gene and drug ca...

  • Article
  • Open Access
7 Citations
2,697 Views
15 Pages

Characterization of Structure and Morphology of Cellulose Lyocell Microfibers Extracted from PAN Matrix

  • Igor Makarov,
  • Ekaterina Palchikova,
  • Markel Vinogradov,
  • Yaroslav Golubev,
  • Sergey Legkov,
  • Petr Gromovykh,
  • Georgy Makarov,
  • Natalia Arkharova,
  • Denis Karimov and
  • Radmir Gainutdinov

Polymer matrices can be reinforced with cellulose fillers in a variety of geometric shapes. Depending on the morphology of the particles, the volume fraction of the composite additive may decrease, while the values of the elastic modulus may increase...

  • Article
  • Open Access
1 Citations
1,981 Views
25 Pages

Evaluation of the Pharmacological Activities of a Xylan from Corn Cobs

  • Rayssa Lourenna Trigueiro Nobrega,
  • Rony Lucas Silva Viana,
  • Marianna Barros Silva,
  • Luciana Duarte Martins Matta,
  • Giulianna Paiva Viana Andrade Souza,
  • Hugo Alexandre Oliveira Rocha and
  • Raniere Fagundes Melo-Silveira

Xylans, polysaccharides abundantly derived from agricultural byproducts, have shown potential pharmacological properties, making them a subject of increasing research interest. This study aimed to expand the understanding of xylans’ pharmacolog...

  • Article
  • Open Access
2 Citations
2,506 Views
18 Pages

Functionalized Bacterial Cellulose: A Potential Sustainable Adsorbent for Methylene Blue Removal

  • Aldo Amaro-Reyes,
  • Karina Marín-Medina,
  • Monserrat Escamilla-García,
  • Sarai E. Favela-Camacho,
  • Oscar Yael Barrón-García,
  • Juan Campos-Guillén,
  • Miguel Angel Ramos-López,
  • Héctor Pool,
  • Eloy Rodríguez-de León and
  • José Alberto Rodríguez Morales

The printing and dyeing industries generate wastewater containing toxic, hard-to-degrade organic dyes like methylene blue (MB). Recent research focuses on biodegradable, renewable materials such as cellulose-based absorbents to address this issue. Th...

  • Article
  • Open Access
1,854 Views
17 Pages

Tuning the Shape of Spray-Dried Pullulan Particles Through Feed Rheological Behavior

  • Francesca Selmin,
  • Francesco Cilurzo and
  • Francesco Briatico Vangosa

Pullulan is a natural polysaccharide used in many health products, including dry powders for oral and pulmonary administration. In these cases, the control of the shape and dimensions of particles is crucial for obtaining the desired functionality. D...

  • Review
  • Open Access
10 Citations
5,982 Views
40 Pages

Polysaccharides: New Frontiers for Nasal Administration of Medicines

  • Adryana Clementino,
  • Giulia Climani,
  • Annalisa Bianchera,
  • Francesca Buttini and
  • Fabio Sonvico

The nasal cavity has become a focal point for drug delivery research. Beyond its use in treating local diseases, the nasal route is appealing due its ability to deliver systemically potent drugs with low oral bioavailability. Recent interest in nasal...

  • Review
  • Open Access
6 Citations
4,238 Views
46 Pages

Polysaccharides: The Sustainable Foreground in Energy Storage Systems

  • Sharin Maria Thomas,
  • Pedro Gómez-Romero and
  • Rosa M. González-Gil

Polysaccharides offer a perfect option as raw materials for the development of a new generation of sustainable batteries and supercapacitors. This is due to their abundance and inherent structural characteristics. Polysaccharides can be chemically fu...

  • Article
  • Open Access
3 Citations
4,615 Views
17 Pages

Antifungal Activity of Nanochitosan in Colletotrichum musae and Colletotrichum chrysophillum

  • Nixe Adriana Hernández-López,
  • Maribel Plascencia-Jatomea,
  • Carmen Lizette Del-Toro-Sánchez,
  • Carmen María López-Saiz,
  • Simón Morales-Rodríguez,
  • Miguel Ángel Martínez-Téllez and
  • Eber Addí Quintana-Obregón

The search for developing materials of natural origin has become imperative due to the resistance shown by phytopathogenic microorganisms to traditional antimicrobial agents. Natural polymers such as chitosan offer a new alternative to fungal infecti...

  • Article
  • Open Access
2 Citations
2,405 Views
18 Pages

There are limited studies in the literature on the surface characterization of modified graphene and graphene oxide and the impact of these modified adsorbents on adsorption performance. In addition, the amine group essentially has a promising affini...

  • Article
  • Open Access
2 Citations
2,710 Views
19 Pages

Corn Stalks-Derived Hemicellulosic Polysaccharides: Extraction and Purification

  • Adrian Cătălin Puițel,
  • Cătălin Dumitrel Balan and
  • Mircea Teodor Nechita

Nowadays, agricultural biomass is one the most valuable sources of natural polysaccharides. In addition to primary agricultural goods, agricultural waste is abundant, diverse, and renewable and can also be utilized as raw material for the production...

  • Article
  • Open Access
9 Citations
2,793 Views
16 Pages

Methyl Orange Adsorption Using Chitosan-Based Composite Aerogels Produced by Supercritical Gel Drying

  • Alessandra Zanotti,
  • Lucia Baldino,
  • Stefano Cardea and
  • Ernesto Reverchon

Dyes abundance in industrial wastewater exerts adverse effects on the environment and human health; adsorption represents a promising remediation strategy. Chitosan-based composites are interesting materials for dye adsorption. In this work, methyl o...

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Polysaccharides - ISSN 2673-4176