A Hypothesis of Autism Approached with the Nonlinear Model †

This paper combined the current brain science development; put forward a novel hypothesis for the pathogenesis of autism which is called Double-Mirror Reflection Model. The camera-monitor experiment’s results and theoretical deduction show that the hypothesis is consistent with the current brain biology cognition and discovery of autism. This hypothesis will provide a new idea for the prevention and diagnosis of autism by the methods of information ecology.


Introduction
With Autism Spectrum Disorder(ASD) ,also known as autism, the patients will appear the phenomena of language disorder, communicating disorder or social disorder who are mostly two or three-year-old boy [1].The pathogenesis of autism is not yet clear.People began to study the etiology of autism from 1943, and have ruled out education and family factors; the consensus is that the cause of autism is mainly caused by brain biology factors.Therefore, this paper intends to propose a hypothesis of autism from the perspective of a nonlinear system, as well as a model to explain this hypothesis, hoping to unify the current phenomenon and Essence of autism, and finally providing a new thinking for the current autism study.

Hypothesis and Experiments
Brain neurons are also similar to "exhaustion", the evolution of species phenomenon [2,3].It also can be called Neuron Plasticity [4].For causality, one explanation is that because of the abnormal structure of the brain leading to abnormal synapses and the formation of pathological neurological loops, so that patients have obstacles of communication and understanding or repetitive behaviors.
In order to explain this phenomenon, this paper presents a "double-mirror reflection" model, as Figure 1 shows: autism is a kind of erroneous iteration of the brain of autistic patients, a positive feedback process of behavior and structure, the patient is not in chaos (which is controllable), but into the cyclical activities.Assuming that we have an observer placed in the center of the mirror, using the observer to observe the phenomenon in the mirror; multi-layer mapping will be find in the mirrors.
To explain this hypothesis, we designed the screen-camera experiment as a simple closed loop in Figure 2.

Results
As Figures A1 and A2 shows, these mapped images simulate a double-mirror reflection model.It further instructs that if the brain has a similar structure, the singular phenomenon as camera-screen experiment shows will emerged in brain due to the continuous stimulation of neurons.

Discussions
According to the hypothesis, there are such mapping areas we called Brain Mirror Reflection Areas in the brain of the patients.In these areas the neurons would be repeatedly stimulated because of the information gotten by the sensory organs of patients which would lead to overgrowth of brain [5][6][7].
Recent study suggests the gene mutations which causes autism involves in the neuron development process [8].It is also well-recognized that visual inputs or behavior activates specific areas of the patient's brain, and Jie Zhang and other researchers have experimentally found that autistic patients exhibit higher variability in specific brain areas [9].The patients obtain some details of the information through some action, which will activate the brain mirror reflection area, thus the abnormal brain structures would lead abnormal behaviors, Then a positive feedback system is formed.
From the methodology of information ecology, we can use the idea of system to deal with the problem in details [10].If this hypothesis model were proved, we can use the method of information ecology to try a way of treating autism by intervening information sources and information recipients, such as visual-brain intervention.By using the visual intervention we can control the visual, auditory, sensory inputs of autistic patients, and by using the brain intervention we can look for ROI (Region of interest) of patients, which we may call double mirror reflection areas, then the brain control equipment can be used on these areas to meddle their growth because of the neuron plasticity.

Conclusions
In this paper, the "double-mirror" hypothesis is proposed for autism, and it is thought that there are areas which have similar function like double mirror reflection.This is a non-linear iterative process, that is, a positive feedback process, which makes the information inputted into the

Figure 1 .
Figure1.Assuming that we have an observer placed in the center of the mirror, using the observer to observe the phenomenon in the mirror; multi-layer mapping will be find in the mirrors.

Figure 2 .
Figure2.The closed-loop system is composed by camera and screen.In the experiment, the pictures taken by the camera is transmitted back to the camera lens again to create a simplest closed loop system.Therefore, the camera lens and the screen, built out of the Double Mirror Reflection model.