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Bioengineering, Volume 2, Issue 3

2015 September - 3 articles

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Articles (3)

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Communication

3 Citations

5,736 Views

8 Pages

Freeze Drying Improves the Shelf-Life of Conductive Polymer Modified Neural Electrodes

Himadri S. Mandal,
Richard O. Cliff and
Joseph J. Pancrazio

Bioengineering2015, 2(3), 176-183;https://doi.org/10.3390/bioengineering2030176

7 August 2015

Coating microelectrodes with conductive polymer is widely recognized to decrease impedance and improve performance of implantable neural devices during recording and stimulation. A concern for wide-spread use of this approach is shelf-life, i.e., the...

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Article

8 Citations

9,261 Views

16 Pages

In Vivo GFP Knockdown by Cationic Nanogel-siRNA Polyplexes

Arun R. Shrivats,
Yuji Mishina,
Saadyah Averick,
Krzysztof Matyjaszewski and
Jeffrey O. Hollinger

Bioengineering2015, 2(3), 160-175;https://doi.org/10.3390/bioengineering2030160

22 July 2015

RNA interference (RNAi) is a powerful tool to treat diseases and elucidate target gene function. Prior to clinical implementation, however, challenges including the safe, efficient and targeted delivery of siRNA must be addressed. Here, we report cat...

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Article

6 Citations

6,533 Views

21 Pages

Ovarian Cancer Cell Adhesion/Migration Dynamics on Micro-Structured Laminin Gradients Fabricated by Multiphoton Excited Photochemistry

Ruei-Yu He,
Visar Ajeti,
Shean-Jen Chen,
Molly A. Brewer and
Paul J. Campagnola

Bioengineering2015, 2(3), 139-159;https://doi.org/10.3390/bioengineering2030139

16 July 2015

Haptotaxis, i.e., cell migration in response to adhesive gradients, has been previously implicated in cancer metastasis. A better understanding of cell migration dynamics and their regulation could ultimately lead to new drug targets, especially for...

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