Comparison of Bone Bruise Pattern Epidemiology between Anterior Cruciate Ligament Rupture and Patellar Dislocation Patients—Implications of Injury Mechanism

Different bone bruise patterns observed using magnetic resonance imaging (MRI) after non-contact anterior cruciate ligament (ACL) rupture and lateral patellar dislocation may indicate different knee injury mechanisms. In this study, 77 ACL ruptures and 77 patellar dislocations in knee MR images taken from patients with bone bruises at our institution between August 2020 and March 2022 were selected and analyzed. In order to determine typical bone bruising patterns following by ACL rupture and patellar dislocation, sagittal- and transverse-plane images were used to determine bone bruise locations in the directions of medial-lateral and superior-inferior with MR images. The presence, intensity, and location of the bone bruises in specific areas of the femur and tibial after ACL rupture and patellar dislocation were recorded. Relative bone bruise patterns after ACL rupture and patellar dislocation were classified. The results showed that there were four kinds of bone bruise patterns (1-, 2-, 3-, and 4- bone bruises) after ACL rupture. The most common two patterns after ACL rupture were 3- bone bruises (including the lateral femoral condyle and both the lateral-medial tibial plateau, LF + BT; both the lateral-medial femoral condyle and the lateral tibial plateau, BF + LT; and the medial femoral condyle and both the medial and lateral tibial plateau, MF + BT) followed by 4- bone bruises (both the lateral-medial femoral condyle and the tibial plateau, BF + BT), 2- bone bruises (the lateral femoral condyle and tibial plateau, LF + LT; the medial femoral condyle and the lateral tibial plateau, MF + LT; the lateral femoral condyle and the medial tibial plateau, LF + MT; the medial femoral condyle and the tibial plateau, MF + MT; both the lateral-medial tibial plateau, 0 + BT), and 1- bone bruise (only the lateral tibial plateau, 0 + LT). There was only a 1- bone bruise (the latera femoral condyle and medial patella bone bruise) for patellar dislocation, and the most common pattern of patellar dislocation was in the inferior medial patella and the lateral anterior inferior femur. The results suggested that bone bruise patterns after ACL rupture and patellar dislocation are completely different. There were four kinds of bone bruise patterns after non-contact ACL rupture, while there was only one kind of bone bruise pattern after patellar dislocation in patients, which was in the inferior medial patella and lateral anterior inferior femur.


Introduction
The acute anterior cruciate ligament (ACL) and medial patellofemoral ligament (MPFL) are two important stable structures of the knee.ACL injury results from the knee suddenly changing landing directions, pivoting, or deceleration, while MPFL injury results from not only kinematic forces but also anatomical abnormalities, such as femur or patella morphological abnormality [1,2].As ACL or MPFL injury will lead to knee pain and functional instability, ACL rupture and patellar dislocation are two of the most considerable knee injury events.So, it is important to explore their injury mechanisms.Previous research has explored the mechanisms of patellar dislocation and ACL rupture, including cadaver studies, numerical simulation studies [3] and video analysis [4,5], which could help to prevent and reduce instances of knee injury, such as ACL rupture and patellar dislocation [6][7][8].Though these methods provide valuable information for an understanding of the motions leading to ACL rupture and patellar dislocation, the knee joint moves in a three-dimensional space of six degrees of freedom; thus, video analysis and simple computer models may not accurately simulate the real motion trajectory of a knee joint injury.Therefore, it is necessary to find a performance that can directly reflect the injury mechanism of ACL rupture and patellar dislocation.
Traumatically related, irregular areas of reduced signal intensity with T1-weighted images and increased intensity on T2-weighted images after a force on the bone or a boneto-bone impact are defined as bone bruises [9].Bone bruises are commonly observed with magnetic resonance imaging (MRI) following ACL rupture or patellar dislocation.As the distribution of the bone bruise is like a footprint left behind by the injury, it can provide an insight into the mechanisms of knee injuries, and the location patterns and severity of bone bruises in patients may indicate the primary mechanisms of non-contact ACL rupture and patellar dislocation [1,10].
In as early as the 1990s, sensitivity intraosseous signal abnormality was found in femoral and tibial bones after ACL rupture by JH Mink, and the medial patellar and lateral femoral after patellar dislocation by E lance [11,12], suggesting that axial MRI can be a valuable adjunct to the evaluation of an acutely injured knee.Previous studies have also shown that observing bone bruises of the knee with MRI could have implications for developing an understanding of the mechanisms of ACL and patellar dislocation injuries [10,11,13].In addition, the femoral and tibial bone bruise patterns after ACL injury differed to the femur and patella bone bruises in patellar dislocation [14,15], Simple ACL rupture bone bruise exists in the femur and (or) tibia, while simple patella dislocation bone bruise exists in the femur and (or) patella because of their different injury mechanisms.Moreover, the distribution of bone bruise caused by ACL rupture is different.Bone bruises occur in both the medial and lateral of the femur and tibia after ACL rupture, suggesting that the knee flexion, and the tibia rotation angle may be different in different people, as the femur bone bruise patterns of patella dislocation patients suggests, and there are actually limited reports that have compared the bone bruise patterns between different knee injuries.
Therefore, the purpose of this retrospective study was to explore the different bone bruise patterns by analyzing the MRI of ACL ruptures and patellar dislocations, which can assist us to better study not only the performance patterns of bone bruises but also the non-contact sports injury mechanisms of ACL ruptures and patellar dislocations.We hypothesized that the bone bruise patterns of ACL rupture and patellar dislocation were completely different, and that there were only lateral femur and medial patellar bone bruises in patellar dislocation while there were both medial and lateral bone bruises of the femur and tibia in ACL rupture.

Selection Criteria and MR Imaging
Institutional ethics committee approval was acceded for the retrospective study (IRB00006761-M2023142).MR images of 77 ACL rupture and 77 patellar dislocation patients were captured at our institution between August 2020 and March 2022, and those that met the inclusion and exclusion criteria were included in the study.The inclusion criteria were (1) ACL rupture or patellar dislocation was confirmed by an experienced radiologist and a sport medicine doctor with the help of MRI; (2) MRI acquired no more than 1 month after ACL rupture and patella dislocation; (3) trauma related to non-contact activity; and (4) patients aged from 18 to 40 years.The 1-month threshold was implemented as far as possible to reduce timing errors, and make sure the signal characteristics of bone marrow edema were consistent [16].Only patients aged from 18 to 40 years were selected because bone mineral density gradually reduces in injuries of patients over 40/50 years old, whose signal characteristics of bone contusion could be affected [17,18].The exclusion criteria were (1) contact injury; (2) other injuries in addition to patella dislocation or ACL rupture; (3) medial or vertical patellar dislocation; and (4) unavailable or unclear MRI.

Determination of Bone Bruise Location
Standard scans were acquired using a 1.5-T scanner (SIGNA (Innsbruck, Austria); GE Healthcare (Chicago, IL, USA)) with a 3.5 mm slice space and 512 × 512 matrix in the sagittal and transverse planes of the injured knee of ACL rupture or patellar dislocation patients.Image slices of the sagittal and transverse sections were used to ensure the bone bruise areas in the medial-lateral and superior-inferior directions, respectively.First, we classified the participants according to whether they were with or without bone bruise; then, the hand-feel region of interest drawing function by ImageJ software (National Institutes of Health, Bethesda, MD, USA, 1.52i) was used to trace the bone bruise borders, and the bone bruise gray values were recorded using imaging pixels.The signal intensity could reflect the impact of bone bruise because the gray value of pixels was obtained according to the MRI signal intensity of the voxel represented in MR images.The maximum gray value of the pixels and the boundary area were measured using ImageJ.The gray value was used to determine how serious of a bone bruise was within an imaging slice in this study.The larger the gray value, the greater the intensity of signal, and the more serious the bone bruise, considering maximum gray value as the site of bone impact.When the same maximum gray value showed on different slices, the level of the bone bruise was further determined according to the area.
Sagittal-and transverse-plane imaging slices were used to determine the location of bone bruises in the lateral-medial and superior-inferior directions (Figures 1 and 2).The precise locations in the lateral-medial direction were confirmed using the following formula [19]: M max is defined as the number of slices at the maximum gray value of all the slices in the order of lateral-medial direction in the sagittal plane while M total is the total number of slices in the sagittal plane based on the slice of bone segments.ML is the measurement of the position in the medial-lateral direction which ranges from 0% (closer to the lateral condyle of the femur or patellar) to 100% (closer to the medial condyle of the femur or patellar).The method of determining the bone bruise location in the superior-inferior direction was similar to that used for determining those on lateral-medial sides of the bone, which uses the following formula: N max is defined as the number of slices at the maximum gray value among all the slices on the superior-inferior sides in the transverse plane, whereas N total is the total number of slices in the transverse plane based on the bone segments.SI is used to measure the location in the superior-inferior direction, and it ranges from 0% (closer to the superior side of the femoral trochlea or patellar) to 100% (closer to the inferior side of the femoral trochlea or patellar).Selecting the image of the largest anterior and posterior diameter of the femoral condyle as the reference, a bone bruise in the femur's most superior end was defined as the location where three slices (10.5 mm) are from the horizontal tangent of the femoral posterior condyle cartilage margin, and bone bruise in the femur's most inferior end was defined as where the horizontal tangent is parallel to the bottom of the femoral condyle in the sagittal plane.
the superior-inferior sides in the transverse plane, whereas Ntotal is the total number of slices in the transverse plane based on the bone segments.SI is used to measure the location in the superior-inferior direction, and it ranges from 0% (closer to the superior side of the femoral trochlea or patellar) to 100% (closer to the inferior side of the femoral trochlea or patellar).Selecting the image of the largest anterior and posterior diameter of the femoral condyle as the reference, a bone bruise in the femur's most superior end was defined as the location where three slices (10.5 mm) are from the horizontal tangent of the femoral posterior condyle cartilage margin, and bone bruise in the femur's most inferior end was defined as where the horizontal tangent is parallel to the bottom of the femoral condyle in the sagittal plane.

Statistical Analysis
The Kolmogorov-Smirnov test was used to evaluate whether the data conformed to a normal distribution.Continuous data were described as the mean ± standard deviation (SD), whereas non-normal distribution data were expressed as the mean with interquartile range, M (Q1, Q3).Categorical data were described as a number.Unpaired Student's t tests were used to detect differences between the ACL rupture and dislocation groups in the continuous variables.Mann-Whitney tests were used to detect differences between the non-normal distribution data for the continuous and categorical variables (age, time from injury, sex, and injury causes) of the ACL rupture and dislocation groups.A p-value of <0.05 was considered statistically significant.

Descriptive Statistics
MR images of 77 ACL ruptures (63 men [81.8%], 14 women [18.2%], aged 29.06 ± 6.09 years) and 77 patellar dislocations (32 men [41.6%], 45 women [58.4%], aged 24.83 ± 6.02 years) in patients at our center who met the inclusion criteria were recorded in this study.The causes of ACL rupture were all sports related, while nearly half of the patellar dislocations were caused by daily activities.The epidemiology of the patients, namely an analysis of their age, BMI, sex, and injury-causing events, was significantly different between the ACL rupture and patellar dislocation groups; ACL rupture patients were significantly younger than patellar dislocation patients, (Table 1).Bone bruises caused by ACL rupture were all in the femur and (or) tibia, while those caused by patellar dislocation were all in femur and patella (Tables 1 and 2).77 (100%) a There were 4 kinds (10 categories) of bone bruise patterns for ACL rupture in femur and tibial bones, as follows: LF + BT, the lateral femoral condyle and both the lateral and medial tibial plateau; BF + LT, both the lateral and medial femoral condyle and lateral tibial plateau; MF + BT, the medial femoral condyle and both the lateral and medial tibial plateau; BF + BT, both the lateral and medial femoral condyle and tibial plateau; LF + LT, the lateral femoral condyle and tibial plateau; MF + LT, the medial femoral condyle and the lateral tibial plateau; LF + MT, the lateral femoral condyle and the medial tibial plateau; MF + MT, the medial femoral condyle and tibial plateau; 0 + BT, only both the lateral and medial tibial plateau; and 0 + LT, only the lateral tibial plateau.

Bone Bruises Patterns of ACL Rupture and Patellar Dislocation
By calculating the position of bone bruises in the sagittal and coronal planes, we determined there were four kinds of bone bruise (1-, 2-, 3-, 4-bone bruises) patterns among the ACL rupture patients (Table 3).The most common two patterns of ACL rupture were three (40%) bone bruises (the lateral femoral condyle and both the lateral and the medial tibial plateau, LF + BT (23%); both the lateral and medial femoral condyle and the lateral tibial plateau, BF + LT (16%); the medial femoral condyle and both the lateral and medial tibial plateau, MF + BT (1%)), followed by four (29%) (both the lateral and medial femoral condyle and tibial plateau, BF + BT) (Figure 3A-H) and two (30%) bone bruises (the lateral femoral condyle and tibial plateau, LF + LT (19%); the medial femoral condyle and the lateral tibial plateau, MF + LT (5%); the lateral femoral condyle and the medial tibial plateau, LF + MT (4%); the medial femoral condyle and tibial plateau, MF + MT (1%); the lateral and medial tibial plateau, 0 + BT (1%)).Just one bone bruise included the lateral tibial plateau (0 + LT, 1%).b There was only 1 kind (7 categories) of bone bruise pattern for patellar dislocation, which only occurred in the lateral femur and medial patella, as follows: MIP + LAIF, medial inferior side of the patellar and lateral anterior inferior of the femoral condyle; MIP + LPIF, medial inferior side of patellar and lateral posterior inferior of the femoral condyle; MIP + LASF, medial inferior side of the patellar and lateral anterior superior of the femoral condyle; MSP + LAIF, medial superior side of the patellar and lateral anterior inferior of the femoral condyle; MIP + LPSF, medial inferior side of the patellar and lateral posterior superior of the femoral condyle; MSP + LASF, medial superior side of the patellar and lateral anterior superior of the femoral condyle; and MSP + LPIF, medial superior side of the patellar and lateral posterior inferior of the femoral condyle.
By calculating the position of bone bruises in the sagittal and transverse planes, we determined there was only one bone bruise pattern (the lateral femur and medial patella bone bruise) for patellar dislocation (Figure 4).The bone bruise was in the inferior medial patella and lateral anterior inferior femur (Table 3), and seven categories of bone bruise characteristics were obtained as follows: MIP + LAIF (medial inferior side of the patellar and lateral anterior inferior of the femoral condyle, 57%); MIP + LPIF (medial inferior side of the patellar and the lateral posterior inferior of the femoral condyle, 22%); MIP + LASF (medial inferior side of the patellar and lateral anterior superior of the femoral condyle, 10%); MSP + LAIF (medial superior side of the patellar and the lateral anterior inferior of femoral condyle, 6%); MIP + LPSF (medial inferior side of the patellar and lateral posterior superior of the femoral condyle, 1%); MSP + LASF (medial superior side of the patellar and lateral anterior superior of the femoral condyle, 1%); and MSP + LPIF (medial superior side of the patellar and the lateral posterior inferior of femoral condyle, 1%).  of the patellar and the lateral posterior inferior of the femoral condyle, 22%); MIP + LASF (medial inferior side of the patellar and lateral anterior superior of the femoral condyle, 10%); MSP + LAIF (medial superior side of the patellar and the lateral anterior inferior of femoral condyle, 6%); MIP + LPSF (medial inferior side of the patellar and lateral posterior superior of the femoral condyle, 1%); MSP + LASF (medial superior side of the patellar and lateral anterior superior of the femoral condyle , 1%); and MSP + LPIF (medial superior side of the patellar and the lateral posterior inferior of femoral condyle, 1%).

Discussion
Our purpose was to summarize, and compare the different bone bruise patterns observed between ACL rupture and patellar dislocation injuries in this study.Previous studies already reported that there were femur and tibial bone bruises for ACL rupture injuries and patellar and femur bone bruises for patellar dislocation injuries [7,9,10,20,21].However, the bone bruise patterns were not systematically counted, and there was no comparison between ACL rupture and patellar dislocation injuries.In total, four types of bone

Discussion
Our purpose was to summarize, and compare the different bone bruise patterns observed between ACL rupture and patellar dislocation injuries in this study.Previous studies already reported that there were femur and tibial bone bruises for ACL rupture injuries and patellar and femur bone bruises for patellar dislocation injuries [7,9,10,20,21].However, the bone bruise patterns were not systematically counted, and there was no comparison between ACL rupture and patellar dislocation injuries.In total, four types of bone bruise patterns after ACL rupture and one type after patellar dislocation were counted and classified in our study, which can help us to understand their different epidemiology characteristics and injury mechanisms (Tables 2 and 3).
Methods were used to explore the mechanisms of knee joint injuries.Relatively consistent bone bruise patterns were revealed with MRI and video analysis in professional football players with acute ACL knee injuries [22].A bone bruise is a phenomenon caused by bone-bone impact or by the bone suffering a heavy on-sided strain, observed in MR images as decreased and increased signal intensities in T1-and T2-weighted scans, respectively [9].Studies have reported femur and patellar bone bruise locations of patellar dislocation patients, as well as femur and tibia bone bruises of ACL injury patients [7,[23][24][25]; however, the location and frequency of those in the coronal section were reported separately and did not combine the sagittal and cross-sectional locations in patients.Furthermore, the femur and patella as well as tibial bones are all three-dimensional structures [3], and the locations of bone bruises in their various sections provide valuable clues as to the associated injuries, which would help in understanding the mechanisms of ACL rupture and patellar dislocation [13,26].Therefore, we hypothesized that the bruise patterns of ACL rupture and patellar dislocation injuries were completely different, and also that there are only lateral femur and medial patella bone bruises in patellar dislocation, while there are both medial and lateral bone bruises of the femoral condyle and tibial plateau in ACL rupture.
To test our hypotheses, we reviewed the MR images of ACL rupture and patellar dislocation patients with bone bruises.Imaging slices of the sagittal and transverse sections were used to quantitatively calculate the relative lateral-medial and superior-inferior direct positions of bone bruises in the distal femur, proximal tibia, and patella.As shown in our study, there were four (1-, 2-, 3-, 4-) kinds of bone bruise patterns for ACL rupture, and the most commonly seen bone bruise patterns were 3-(LF + BT, BF + LT, MF + BT), followed by 4-(BF + BT) and 2-bone bruises (LF + LT, MF + LT, LF + MT, MF + MT, 0 + BT; Table 2) in the femur and tibia, while there was only one bone bruise pattern for patellar dislocation, which was in the lateral femur and medial patella (Figures 1 and 2, Table 3).ACL rupture and patellar dislocation injuries had completely different bone bruise patterns, which may represent the different injury mechanisms of the knee.The ACL rupture patients displayed 3-or 4-bone bruises with either 1 or 2 femoral, bone bruises and 2 tibial bone bruises, suggesting that the knee joint was unstable when the ACL was injured, not only in the anterior, which translated the tibia to the femur, but also through obvious shaking in the medial-lateral direction at the time of the trauma to the knee.Similarly, the differences in the superior-inferior direct positions of femoral and patellar bone bruises in patellar dislocation also indicated that different bone bruise patterns reflect different knee flexion angles at the time of injury (Figure 4).
Despite many studies on the location of bone bruises, they have only pointed out the characteristics of the bone bruises, and there was no description of the specific location, nor has there been a systematic report on the pattern classification of bone bruises after ACL rupture and patellar dislocation [10,23,25].Our study not only recorded the bone bruises but also calculated the specific locations of bone bruises after ACL rupture and patellar dislocation (Figure 5).For non-contact-sport knee injuries, a bone bruise is not only an intensity signal but also a footprint of the damage process, which could provide information about the injury mechanism or its product, because different mechanisms of injury have different bone bruise patterns [14].Numerical optimization was used by Kim Sophia Y et al. to maximize the overlap of the bone bruises on the femur and tibia and to predict the position of injury for the most common 3-and 4-bone bruises for ACL rupture, establishing an infrastructure to create three-dimensional surface models.They found that landing on an extended knee results in a high risk of ACL injury [7,20], while others found that the knee valgus is a critical component of the injury mechanism [5,27,28].However, the initial injury mechanism of 3-and 4-bone bruises after ACL rupture was different.Our study found that the bone bruise patterns of ACL rupture and patellar dislocation injuries were completely different.This is related to their different anatomical structures because ACL rupture is caused by an instantaneous impact of the femur and tibial bones, while patellar dislocation is caused by injury of the medial patellofemoral ligament, partly due to the abnormal anatomy of the patella and femur [29,30].
Although the bone bruise patterns were completely different, they represent their own sports injury mechanisms.It was found that the video analysis was consistent with the pattern of bone bruising, which showed that it was feasible and scientific to analyze the injury mechanism according to the bone bruise, and it was also mentioned that although they constitute the same kind of injury, different bone bruise patterns may represent different sports injury mechanism patterns [22,31,32].A more scientific and targeted model of combined specific bone bruise manifestation needs to be established to explore the mechanisms of non-contact sports injuries [33].
In addition, the characteristics of the patient cohort, including age, sex, and injurycausing events, were significantly different between the ACL rupture and patellar dislocation groups (Table 1).The age of the patellar dislocation patients was significantly younger than that of ACL rupture patients, and there were more men (81.8%) in the ACL rupture group, while there were more women (58.4%) in the patellar dislocation group.Although the rate of ACL rupture was three times higher in men [34], the results of this study take into consideration that this was due to the higher total number of men participating in high-level sports, producing an increased number of people encountering tibial forward movement as well as landing torsion, which are the risk factors for ACL injury [35].In our study, the causes of ACL rupture were all sports (100%), while sporting causes of patellar dislocation only accounted for 54.5%, and the remaining 45.5% resulted from daily activities.As for patellar dislocation patients, almost all of them had anatomical abnormalities [36,37], which is more common among women, especially in children, resulting in the patella slipping to the outside of the knee joint more easily, not only in sports activities, but also during everyday-life knee flexion and torsion motion [38][39][40].
Bioengineering 2023, 10, x FOR PEER REVIEW 10 of 1 injuries were completely different.This is related to their different anatomical structure because ACL rupture is caused by an instantaneous impact of the femur and tibial bone while patellar dislocation is caused by injury of the medial patellofemoral ligament, partl due to the abnormal anatomy of the patella and femur [29,30].Although the bone bruise patterns were completely different, they represent the own sports injury mechanisms.It was found that the video analysis was consistent wit the pattern of bone bruising, which showed that it was feasible and scientific to analyz the injury mechanism according to the bone bruise, and it was also mentioned that al hough they constitute the same kind of injury, different bone bruise patterns may repre sent different sports injury mechanism patterns [22,31,32].A more scientific and targete model of combined specific bone bruise manifestation needs to be established to explor the mechanisms of non-contact sports injuries [33].
In addition, the characteristics of the patient cohort, including age, sex, and injury causing events, were significantly different between the ACL rupture and patellar dislo cation groups (Table 1).The age of the patellar dislocation patients was significantl younger than that of ACL rupture patients, and there were more men (81.8%) in the AC rupture group, while there were more women (58.4%) in the patellar dislocation group Although the rate of ACL rupture was three times higher in men [34], the results of th study take into consideration that this was due to the higher total number of men partic pating in high-level sports, producing an increased number of people encountering tibia forward movement as well as landing torsion, which are the risk factors for ACL injur [35].In our study, the causes of ACL rupture were all sports (100%), while sporting cause of patellar dislocation only accounted for 54.5%, and the remaining 45.5% resulted from daily activities.As for patellar dislocation patients, almost all of them had anatomical ab normalities [36,37], which is more common among women, especially in children, resul ing in the patella slipping to the outside of the knee joint more easily, not only in spor activities, but also during everyday-life knee flexion and torsion motion [38][39][40].
In addition to the above characteristics, we also found an interesting phenomenon In addition to the above characteristics, we also found an interesting phenomenon.In the ACL injury patients, the sagittal MR images accounting for 90% of the images (Figure 6) in our study had an obvious lateral femoral notch (LFN), which didn't exist in patellar dislocation patients.A LFN is a radiological feature observed in the MRI in the sagittal plane of the lateral femoral condyle.The LFN depth may lead to a decrease in the contact area between the distal femur and the proximal tibia, and may result in altered knee kinematics and instability.However, how the LFN affects the knee kinematics actually was still unclear.Ajay et al. indicated that LFN depth was not associated with increased rotatory instability [41], while Gian et al. hold that LFNs are correlated with increased rotatory laxity after ACL injury [42].But they all agreed with the idea that an LFN is a concomitant of posterior root tears of the lateral meniscus [43].The relationship between LFNs and the femur and tibia, especially when valgus stresses are applied, along with external tibial rotation should be further explored in future research.For patellar dislocation patients, the location of bone bruise was on the lateral condyle of the superior or inferior femur, which was also very interesting.Since the accepted risk knee angle of patellar dislocation was flexion of 20-30 degrees, the inferior femur bone bruise suggests that the knee joint experienced an enlarged knee flexion angle when patellar dislocation occurred, which should be also further explored in future research.
with external tibial rotation should be further explored in future research.For pat dislocation patients, the location of bone bruise was on the lateral condyle of the sup or inferior femur, which was also very interesting.Since the accepted risk knee ang patellar dislocation was flexion of 20-30 degrees, the inferior femur bone bruise sug that the knee joint experienced an enlarged knee flexion angle when patellar disloc occurred, which should be also further explored in future research.

Limitation
There are several limitations of our study.First, the sample size was too small t flect the difference between ACL rupture and patellar dislocation with patient inform and bone bruise patterns.Second, we did not compare the anatomical indexes betw the ACL rupture and patellar dislocation patients.

Limitation
There are several limitations of our study.First, the sample size was too small to reflect the difference between ACL rupture and patellar dislocation with patient information and bone bruise patterns.Second, we did not compare the anatomical indexes between the ACL rupture and patellar dislocation patients.

Figure 1 .
Figure 1.Method of calculating the location of a bone bruise to classify the bone bruise pattern of ACL rupture in sagittal plane.*, represents multiplication.

Figure 1 .
Figure 1.Method of calculating the location of a bone bruise to classify the bone bruise pattern of ACL rupture in sagittal plane.*, represents multiplication.

Figure 2 .
Figure 2. Method of calculating bone bruise location to classify the bone bruise pattern of patellar dislocation in sagittal and transverse planes.*, represents multiplication.

Figure 6 .
Figure 6.Lateral femoral notch sign on sagittal T2-weighted magnetic resonance imaging in a anterior cruciate ligament injury.

Figure 6 .
Figure 6.Lateral femoral notch sign on sagittal T2-weighted magnetic resonance imaging in an anterior cruciate ligament injury.
a BMI, Body Mass Index.

Table 2 .
Bone bruise patterns of ACL rupture a .

Table 3 .
Bone bruise patterns of patellar dislocation b .