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Open AccessCase Report

A Case of Bullous Rash Apparently Triggered by Meningococcal and Rotavirus Vaccines in an Infant: Focus on Infantile Bullous Pemphigoid

Dermatology—IRCCS Policlinico di Sant’Orsola—Department of Experimental, Diagnostic and Specialty Medicine (DIMES), Alma Mater Studiorum-University of Bologna, 40138 Bologna, Italy
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Academic Editor: Gürkan Kaya
Dermatopathology 2021, 8(1), 33-36; https://doi.org/10.3390/dermatopathology8010006
Received: 19 January 2021 / Revised: 11 February 2021 / Accepted: 13 February 2021 / Published: 23 February 2021
Bullous pemphigoid (BP) is an autoimmune bullous disease and is a rare condition in childhood. Acquired tense acral bullae and fixed urticarial annular lesions on the trunk are diagnostic clues of infantile BP. Diagnosis is supported by immunosorbent assay (IgG anti-BP180 and BP230) and direct immunofluorescence (linear deposition of IgG at the dermo-epidermal junction). Topical and/or systemic corticosteroids are the first-line treatment. The prognosis is good with a self-limited clinical course. Differential diagnoses include impetigo and other bullous diseases in children, such as dermatitis herpetiformis, linear IgA bullous dermatosis and erythema multiforme. The etiopathogenesis is still unknown, and the role of antigen stimuli such as infections, drugs and vaccination is still debated.
Keywords: autoimmune bullous rash; bullous pemphigoid; infants; vaccine autoimmune bullous rash; bullous pemphigoid; infants; vaccine
MDPI and ACS Style

Neri, I.; Evangelista, V.; Guglielmo, A.; Sechi, A.; Virdi, A. A Case of Bullous Rash Apparently Triggered by Meningococcal and Rotavirus Vaccines in an Infant: Focus on Infantile Bullous Pemphigoid. Dermatopathology 2021, 8, 33-36. https://doi.org/10.3390/dermatopathology8010006

AMA Style

Neri I, Evangelista V, Guglielmo A, Sechi A, Virdi A. A Case of Bullous Rash Apparently Triggered by Meningococcal and Rotavirus Vaccines in an Infant: Focus on Infantile Bullous Pemphigoid. Dermatopathology. 2021; 8(1):33-36. https://doi.org/10.3390/dermatopathology8010006

Chicago/Turabian Style

Neri, Iria; Evangelista, Valeria; Guglielmo, Alba; Sechi, Andrea; Virdi, Annalucia. 2021. "A Case of Bullous Rash Apparently Triggered by Meningococcal and Rotavirus Vaccines in an Infant: Focus on Infantile Bullous Pemphigoid" Dermatopathology 8, no. 1: 33-36. https://doi.org/10.3390/dermatopathology8010006

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