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Article

High Visceral Fat Area Attenuated the Negative Association between High Body Mass Index and Sarcopenia in Community-Dwelling Older Chinese People

1
National Institute for Nutrition and Health, Chinese Center for Disease Control and Prevention, 27 Nanwei Road, Xicheng District, Beijing 100050, China
2
Wuyuan County Center for Disease Control and Prevention, 105 Shiji Road, Wuyuan, Inner Mongolia 015100, China
3
Yuexiu District Center for Disease Control and Prevention, 23 Jiaochang West Road, Guangzhou 510030, China
4
Taicang City Center for Disease Control and Prevention, 36 Xianfu West Street, Taicang 215400, China
*
Author to whom correspondence should be addressed.
Healthcare 2020, 8(4), 479; https://doi.org/10.3390/healthcare8040479
Received: 16 October 2020 / Revised: 8 November 2020 / Accepted: 10 November 2020 / Published: 12 November 2020
(This article belongs to the Special Issue Nutrition Disorders in Older Adults)
The association between obesity and sarcopenia remains controversial. The present study was conducted to explore the associations among body mass index (BMI), visceral fat area (VFA), and sarcopenia in older people and analyze their potential mechanisms. This cross-sectional study included 861 community-dwelling older Chinese people from three regions of China. BMI, VFA, muscle mass, muscle strength, physical performance, body composition, and metabolic markers were measured. Muscle mass and muscle strength were positively correlated with BMI, but were negatively correlated with VFA. Simple overweight/obesity was negatively associated with sarcopenia (OR = 0.07, 95% CI = 0.03~0.18), and the OR value was lower than combined obesity (OR = 0.16, 95% CI = 0.09~0.28). Fat free mass and total body protein were positively associated with high BMI but negatively associated with high VFA. Furthermore, high VFA was adversely associated with some metabolic risk factors of sarcopenia. Combination of BMI and VFA increased diagnostic efficiency of low muscle mass and sarcopenia. In conclusion, high BMI was negatively associated with sarcopenia, while high VFA attenuated the negative association between high BMI and sarcopenia. The opposite association may partially be attributed to their different associations with body composition and metabolic risk factors of sarcopenia. Therefore, bedsides BMI, VFA and its interaction with BMI should be considered in sarcopenia prevention. View Full-Text
Keywords: sarcopenia; body mass index; visceral fat area; obesity; community-dwelling older people sarcopenia; body mass index; visceral fat area; obesity; community-dwelling older people
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MDPI and ACS Style

Li, C.; Kang, B.; Zhang, T.; Gu, H.; Man, Q.; Song, P.; Liu, Z.; Chen, J.; Wang, X.; Xu, B.; Zhao, W.; Zhang, J. High Visceral Fat Area Attenuated the Negative Association between High Body Mass Index and Sarcopenia in Community-Dwelling Older Chinese People. Healthcare 2020, 8, 479. https://doi.org/10.3390/healthcare8040479

AMA Style

Li C, Kang B, Zhang T, Gu H, Man Q, Song P, Liu Z, Chen J, Wang X, Xu B, Zhao W, Zhang J. High Visceral Fat Area Attenuated the Negative Association between High Body Mass Index and Sarcopenia in Community-Dwelling Older Chinese People. Healthcare. 2020; 8(4):479. https://doi.org/10.3390/healthcare8040479

Chicago/Turabian Style

Li, Cheng, Bingxian Kang, Ting Zhang, Hongru Gu, Qingqing Man, Pengkun Song, Zhen Liu, Jingyi Chen, Xile Wang, Bin Xu, Wenhua Zhao, and Jian Zhang. 2020. "High Visceral Fat Area Attenuated the Negative Association between High Body Mass Index and Sarcopenia in Community-Dwelling Older Chinese People" Healthcare 8, no. 4: 479. https://doi.org/10.3390/healthcare8040479

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