Dark Matter Axions, Non-Newtonian Gravity and Constraints on Them from Recent Measurements of the Casimir Force in the Micrometer Separation Range

: We consider axionlike particles as the most probable constituents of dark matter, the Yukawa-type corrections to Newton’s gravitational law and constraints on their parameters following from astrophysics and different laboratory experiments. After a brief discussion of the results by Prof. Yu. N. Gnedin in this ﬁeld, we turn our attention to the recent experiment on measuring the differential Casimir force between Au-coated surfaces of a sphere and the top and bottom of rectangular trenches. In this experiment, the Casimir force was measured over an unusually wide separation region from 0.2 to 8 µ m and compared with the exact theory based on ﬁrst principles of quantum electrodynamics at nonzero temperature. We use the measure of agreement between experiment and theory to obtain the constraints on the coupling constant of axionlike particles to nucleons and on the interaction strength of a Yukawa-type interaction. The constraints obtained on the axion-to-nucleon coupling constant and on the strength of a Yukawa interaction are stronger by factors of 4 and 24, respectively, than those found previously from gravitational experiments and measurements of the Casimir force but weaker than the constraints following from a differential measurement where the Casimir force was nulliﬁed. Some other already performed and planned experiments aimed at searching for axions and non-Newtonian gravity are discussed, and their prospects are evaluated.


Introduction
The problem of dark matter has a long history [1]. As found by J. Oort in 1932 when studying stellar motion in the neighborhood of a galaxy, the galaxy mass must be well over than that of its visible constituents [2]. A year later, F. Zwicky [3] applied the virial theorem to the Coma cluster of galaxies in order to determine its mass. The obtained mass value turned out to be much larger than that found from the number of observed galaxies belonging to the Coma cluster multiplied by their mean mass. An excess mass, which reveals itself only gravitationally, received the name dark matter.
According to current concepts, dark matter contributes to approximately 27% of the energy of the universe although its physical nature remains unknown. There are many approaches to this problem based on the role of some hypothetical particles, such as axions, arions, massive neutrinos, weakly interacting massive particles (WIMP), barionic dark matter, modified gravity, etc. (see [1,[4][5][6][7][8] for a review).
The model of dark matter that finds support from astrophysics and cosmology is referred to as cold dark matter. According to this model, dark matter consists of light hypothetical particles that are produced in the early universe and become nonrelativistic already at the first stages of its evolution. The most popular particle of this kind is an axion, i.e., a pseudoscalar Nambu-Goldstone boson introduced to solve the problem of strong CP violation in Quantum Chromodynamics (QCD) [9][10][11]. It has been known that the gauge invariant QCD vacuum depends on an angle θ, and that this dependence violates the CP invariance of QCD. However, experiments suggest that strong interactions are CP invariant and that the electric dipole moment of a neutron is equal to zero up to a high degree of accuracy. An introduction of the Peccei-Quinn symmetry and axions, which are connected with its violation, helps to solve this problem.
Axions and other axionlike particles that arise in many extensions to the Standard Model can interact both with photons and with fermions (electrons and nucleons). These interactions are used for an axion search and for constraining axion masses and coupling constants from observations of numerous astrophysical and cosmological processes as well as from various laboratory experiments (see reviews [1,[4][5][6][7][8][12][13][14][15][16][17][18][19][20] of already obtained bounds on the axion mass and coupling constants to photons, electrons and nucleons).
Prof. Yuri N. Gnedin obtained many important results investigating the interaction of dark matter axions with photons in astrophysics and cosmology. He proposed [21] to employ the polarimetric methods for a search for axions and arions (i.e., the axions of zero mass [22]) in the emission from pulsars, X-ray binaries with low-mass components, and magnetic white dwarfs. For this purpose, he used the conversion process of photons into axions in the magnetic field of compact stars and in the interstellar and intergalactic space (i.e., the Primakoff effect). Next, Prof. Gnedin demonstrated an appearance of the striking feature in the polarized light of quasistellar objects due to the resonance magnetic conversion of photons into massless axions [23].
Using these results, Prof. Yu. N. Gnedin organized the axion search by the 6 m telescope at the Special Astronomical Observatory in Russia. Both the Primakoff effect and the inverse process of an axion decay into two photons were searched for in the integalactic light of clusters of galaxies and in the brightness of night sky due to axions in the halo of our galaxy [24]. Although no evidences of axions were found, it was possible to find the upper limit on the photon-to-axion coupling constant from the polarimetric observations of magnetic chemically peculiar stars of spectral type A possessing strong hydrogen Balmer absorption lines [24]. The above results, as well as the ground-based cavity experiments searching for galactic axions, searches of an axion decay in the galactic and extragalactic light, for the solar and stellar axions, and the limits obtained on the coupling constant of axions to photons, were discussed in a review [25].
In their further research on dark matter axions, Yu. N. Gnedin and his collaborators analyzed [26] the intermediate results of PVLAS experiments interpreted [27] as arising due to a conversion of photons into axions with a coupling constant to photons of the order of 4 × 10 −6 GeV −1 . By considering the astrophysical and cosmological constraints, they have shown [26] that this result is in contradiction with the data on stellar evolution that exclude the standard model of QCD axions.
Using the cosmic orientation of the electric field vectors of polarized radiation from distant quasars, Yu. N. Gnedin and his collaborators placed a rather strong limit on the coupling constant of axions to an electric field [28]. Numerous results related to the processes of axion decay into two photons, the transformation of photons into axions in the magnetic fields of stars and of interstellar or intergalactic media, and the transformation of axions generated in the cores of stars into X-ray photons were discussed in a review [29].
It has been known that the coupling constant of axionlike particles to fermions can be constrained in the laboratory experiments measuring the Casimir force between two closely spaced test bodies. This force is caused by the zero-point and thermal fluctuations of the electromagnetic field. It acts between any material surfaces-metallic, dielectric or semiconductor [30,31]. A constraint on the electron-arion coupling constant from old measurements of the Casimir force [32] was obtained in [33]. The competitive constraints on the coupling constants of axionlike particle to nucleons from different experiments measuring the Casimir interaction were obtained in [34][35][36][37][38][39][40][41]. All experiments used for obtaining these constraints have been performed in the separation range below 1 µm.
Starting from 1982 [42], measurements of the van der Waals and Casimir forces were also used for constraining the Yukawa-type corrections to Newton's law of gravitation. These corrections arise due to an exchange of light scalar particles between atoms of two closely spaced macrobodies [43] and in the extra-dimensional unification schemes with a low-energy compactification scale [44][45][46][47]. A review of the most precise measurements of the Casimir interaction and constraints on non-Newtonian gravity obtained from them can be found in [20,48].
In this paper, we obtain new constraints on the coupling constant of axionlike particles to nucleons and on the Yukawa-type corrections to Newtonian gravity following from recent experiment measuring the differential Casimir force between two Au-coated bodies spaced at separations from 0.2 to 8 µm [49]. This experiment was performed by Prof. R. S. Decca by means of a micromechanical torsional oscillator. The differential Casimir force was measured between an Au-coated sapphire sphere and the top and bottom of Au-coated deep Si trenches. The measurement results were compared with the exact theory using the scattering approach and were found to be in good agreement with it over the entire measurement range with no fitting parameters under the condition that the relaxation properties of conduction electrons are not included in the computations. Another theoretical approach that takes into account the relaxation properties of conduction electrons was excluded by the measurement data over the range of separations from 0.2 to 4.8 µm [49].
We calculate additional forces arising in the experimental configuration due to an exchange of two axionlike particles between nucleons of the test bodies as well as due to the Yukawa-type correction to Newton's gravitational potential. Taking into account that no extra force was observed, the constraints on the masses and coupling constants of axions and on the strength and interaction range of the Yukawa interaction were found from the extent of agreement between the measured and calculated Casimir forces.
According to our results, the obtained constraints on axionlike particles are up to a factor of 4 stronger than those from other measurements of the Casimir force. The new constraints on the Yukawa-type interaction are up to a factor of 24 stronger than those obtained previously when measuring the Casimir force. Stronger constraints on an axion [38] and non-Newtonian gravity [50] were obtained only from the experiment by R. S. Decca [50], where the Casimir force was completely nullified.
The paper is organized as follows. In Section 2, we consider the effective potentials due to an exchange of pseudoscalar and scalar particles. Section 3 is devoted to a brief discussion of recent experiments on measuring the differential Casimir force in the micrometer range. In Section 4, we calculate additional forces due to an exchange of two axionlike particles between nucleons and obtain constraints on the axion mass and coupling constant. The constraints on the Yukawa-type correction to Newtonian gravity are found in Section 5. In Sections 6 and 7, the reader can find a discussion of the results obtained and our conclusions, respectively. We use a system of units withh = c = 1.

Effective Potentials Due to Exchange of Pseudoscalar and Scalar Particles
An interaction of the field of originally introduced QCD axions a(x) [9][10][11], which describes the Nambu-Goldstone bosons, with the fermionic field ψ(x) is given by the pseudovector Lagrangian density [12,15] where m a is the mass of an axion, γ n with n = 0, 1, 2, 3, 4, 5 are the Dirac matrices, and g is the dimensionless coupling constant of the axions to fermionic particles of spin 1/2 (in our case a proton or a neutron).
The axionlike particles introduced in Grand Unified Theories (GUT) interact with fermions by means of the pseudoscalar Lagrangian density [12,15,51] L ps (x) = −igψ(x)γ 5 ψ(x)a(x). (2) On a tree level, the Lagrangian densities (1) and (2) result in the same action and common effective potential due to an exchange of one axion or axionlike particle between two nucleons of mass m spaced at a distance r = | r 1 − r 2 | [52,53] V an (r; σ 1 , wherer = ( r 1 − r 2 )/r is the unit vector directed along the line connecting the two nucleons and σ 1 , σ 2 are their spins. Here, we assume that the coupling constants of an axion to a neutron and a proton are equal and denote m as their mean mass. Taking into account that the effective potential (3) is spin-dependent, the resulting additional force averages to zero when integrated over the volumes of unpolarized test bodies used in experiments on measuring the Casimir force. Therefore, the process of oneaxion exchange cannot be used for the axion search in measurements of the Casimir force performed until now [31,54] (the proposed measurement of the Casimir force between two test bodies possessing the polarization of nuclear spins [55] is, however, quite promising for this purpose).
A process of the two-axion exchange between two nucleons deserves particular attention. If the pseudovector Lagrangian density (1) is used, the respective effective potential is still unknown. This is because the actual interaction constant g/(2m a ) is dimensional, and the resulting quantum field theory is nonrenormalizable (the current status of this problem is reflected in [56]). However, in the case of the pseudoscalar Lagrangian density (2) describing the interaction of axionlike particles with fermions, the effective potential due to a two-axion exchange is spin-independent and takes the following simple form [43,57,58]: where K 1 (z) is the modified Bessel function of the second kind. The effective potential (4) can be summed over all pairs of nucleons belonging to the test bodies V 1 and V 2 , leading to their total interaction energy where n 1 and n 2 are the numbers of nucleons per unit volume of the first and second test bodies, respectively, and z is the closest separation distance between them. Finally, from (5), one arrives at the additional force acting between the test bodies due to the two-axion exchange Equations (5) and (6) can be used to search for axionlike particles in experiments measuring the Casimir force and for constraining their parameters.
A similar situation takes place for the Yukawa-type corrections to Newton's gravitational law, which arise due to an exchange of one scalar particle of mass m s between two pointlike particles (atoms or nucleons) with masses m 1 and m 2 separated by a distance r. It is conventional to notate the coupling constant of the Yukawa interaction as αG, where G is the Newtonian gravitational constant and α is the proper dimensionless Yukawa strength. Then, the Yukawa-type correction to Newtonian gravity takes the form where the interaction range λ = 1/m s represents the Compton wavelength of a scalar particle. As was mentioned in Section 1, the same correction to the Newton's gravitational potential also arises in extra-dimensional physics with a low-energy compactification scale [44][45][46][47].
The Yukawa-type interaction energy between two macrobodies V 1 and V 2 arising due to the potential (7) is given by where ρ 1 and ρ 2 are the mass densities of the first and second test bodies, respectively. In this case, the additional force acting between two test bodies is equal to Both hypothetical forces (6) and (9) act on the background of the Casimir force measured at separations below a few micrometers. Note that the Newtonian gravitational force calculated within the same range of separations is much less than the error in measuring the Casimir force and can be neglected (see below).

Measurements of the Casimir Force in the Micrometer Separation Range
All experiments measuring the Casimir force between two macrobodies used for obtaining constraints on axionlike particles [35][36][37][38][39][40][41] were performed at separations below a micrometer. A single direct measurement of the Casimir force between two macrobodies at separations up to 8 µm was reported quite recently and compared with theory with no fitting parameters [49]. Below, we briefly elucidate the main features of this experiment needed for obtaining new constraints on the axionlike particles and Yukawa-type corrections to Newtonian gravity.
In the experiment [49], the micromechanical torsional oscillator was used to measure the differential Casimir force between an Au-coated sapphire sphere of R = 149.7 µm radius and the top and bottom of Au-coated rectangular silicon trenches of H = 50 µm depth. Such a large depth of the trenches was chosen in order for the Casimir force between a sphere and a trench bottom (and all the more additional hypothetical forces) to be equal to zero. This means that the actually measured Casimir force F C (z) acts between a sphere and a trench top. In so doing, however, the differential measurement scheme used allowed us to reach a rather low total experimental error equal to ∆F C = 2.2 fN at the separation distance of z = 3 µm. Similar schemes of differential force measurements were previously used in [50,[59][60][61].
The thicknesses of Au coatings on the sphere and the trench surfaces equal to Au = 150 nm, respectively, were thick enough in order for Au-coated test bodies to be considered made from solid Au when calculating the Casimir force. For technological reasons, before depositing Au coatings, the sapphire sphere and silicon trench surfaces were also covered with Cr layers of thickness d Cr = 10 nm. These layers do not influence the Casimir force but should be accounted for in calculations of the additional forces due to two-axion exchange and the Yukawa-type potential in Sections 4 and 5, respectively. The Casimir force between an Au-coated sphere and an Au-coated trench top was measured over the separation region 0.2 µm z 8 µm and compared with an exact theory developed in the sphere-plate geometry using the scattering approach in the plane-wave representation [62][63][64] and the derivation expansion [65][66][67][68]. In doing so, the contribution of patch potentials to the measured signal was characterized by Kelvin probe microscopy. An impact of surface roughness was taken into account perturbatively [31,54,69,70] and was found to be negligible. It was shown [49] that the measurement data are in agreement with theory to within the total experimental error ∆F C over the entire measurement range if the relaxation properties of conduction electrons are not included in computations. An inclusion of the relaxation of conduction electrons (i.e., using the dissipative Drude model at low frequencies) results in a strong contradiction between experiment and theory over the range of separations from 0.2 to 4.8 µm. These results are in line with previous precise experiments on measuring the Casimir interaction at shorter sphere-plate separations [61,[71][72][73][74][75][76][77][78][79][80][81] and discussions of the so-called Casimir puzzle [82][83][84] (see also recent approaches to the resolution of this problem [85][86][87]).
It is necessary to stress that calculation of the Casimir force between the first test body (sphere) and the flat top of rectangular trenches in [49] was based on first principles of quantum electrodynamics at nonzero temperature and did not use any approximate methods, such as the proximity force approximation applied in the most of previously performed experiments [31,54] or fitting parameters. As for the total experimental errors ∆F C , they were found in [49] at the 95% confidence level as a combination of both random and systematic errors.
Notice that, according to [88,89], the same experiment cannot be used to exclude an alternative model and to constrain the fundamental forces. This claim was made in 2011 when some of the background effects in the Casimir force (such as the role of patch potentials) and theoretical uncertainties (such as an error in the proximity force approximation) were not completely settled. As was, however, immediately objected in the literature [90,91], such a difference between the excluded and confirmed models of the Casimir force is of a form quite different from a correction to the fundamental force. This fact allows us to constrain the parameters of the latter. After the seminal experiment by R. S. Decca performed in 2016 [61], where the theoretical predictions of two models for the Casimir force differed by up to a factor of 1000 and one of them was conclusively rejected whereas another one was confirmed, it became amply clear that a comparison with the confirmed model can be reliably used for constraining the fundamental forces in all subsequent experiments.
When discussing the measure of agreement between experiment and theory, it is necessary also to take into account the contribution of differential Newtonian gravitational force between the sphere and the top and bottom of rectangular trenches. In [49] this force was assumed to be negligibly small. Taking into account that in Sections 4 and 5 the measure of agreement between experiment and theory is used for constraining the parameters of axionlike particles and non-Newtonian gravity, below we estimate the role of Newton's gravitational force more precisely.
The second test body, which is concentrically covered by the rectangular trenches, is a D = 25.4 mm diameter Si disc (schematic of the experimental setup is shown in Figure 1 of [49]). As mentioned above, both of the test bodies are coated by layers of Cr and Au. In our estimation of the upper bound for the Newton's gravitational force in this experiment, we assume that both the sphere and the disc of diameter D and thickness H, where H is the trench depth, are all-gold. By choosing the disc thickness equal to H, we disregard the Si substrate underlying trenches because it does not contribute to the differential gravitational force between the top and bottom of the trenches (unlike the Casimir and additional hypothetical forces, the more long-range gravitational force from the trench bottom cannot be considered equal to zero).
Taking into account that the disc radius D/2 is much larger that the sphere radius R, the gravitational force between them is given by [92] where ρ Au = 19.28 g/cm 3 is the density of gold. Substituting the values of all parameters in (11), one obtains F gr = 0.11 fN. It is seen that the upper bound for the gravitational force is much less than the experimental error in measuring the Casimir force, which is equal to ∆F C = 2.2 fN at z = 3 µm (the variations in gravitational force depending on whether the sphere is above the top or bottom of the trenches are well below 0.11 fN). This confirms that the contribution of Newton's gravitational force in this experiment is very small and can be neglected.

Constraints on Axionlike Particles
The results of the experiment [49] measuring the Casimir force in the micrometer seperation range allow us to obtain new constraints on the mass of axionlike particles and their coupling constants to nucleons. As explained in Section 2, measurements of the Casimir force between unpolarized test bodies can be used for constraining the parameters of axionlike particles in which interaction with fermions is described by the Lagrangian density (2). For this purpose, one should use the process of two-axion exchange between nucleons of the laboratory test bodies, which leads to the effective potential (4) and force (6). Thus, it is necessary to calculate this force in the experimental configuration of [49].
According to Section 3, this configuration reduces to a sapphire (Al 2 O 3 ) sphere of radius R (the sapphire density is ρ Al 2 O 3 = 4.1 g/cm 3  The additional force arising in this configuration due to a two-axion exchange can be calculated by (5) and (6). The results of this calculation for a homogeneous sphere and plate are presented in [41]. The impact of two metallic layers is easily taken into account in perfect analogy to [38,40]. Finally, the additional force due to a two-axion exchange in the configuration of the experiment [49] takes the form where m H is the mass of atomic hydrogen and the following expressions for the functions X t (x) and X s (x) are obtained: where the function Φ is defined as The numerical coefficients C in (13) are specific for any material. They are calculated by the following equation: where Z and N are the number of protons and the mean number of neutrons in an atomic nucleus of a given substance, and µ = M/m H with M being the mean atomic or molecular mass. The values of (15) for Au, Cr, Si and Al 2 O 3 , i.e., C Au , C Cr , C Si and C Al 2 O 3 , are proportional to g 2 with the factors found using the densities of Au, Si and Al 2 O 3 indicated above and ρ Cr = 7.15 g/cm 3 . The values of Z/µ for Au, Cr, Si and Al 2 O 3 are equal to 0.40422, 0.46518, 0.50238 and 0.49422, respectively, and those of N/µ are equal to 0.60378, 0.54379, 0.50628 and 0.51412 for the same respective materials [43].
Taking into consideration that, in the experiment [49], no additional interaction was observed within the total experimental error ∆F C (z), the interaction (12) should satisfy the inequality |F aan (z)| ∆F C (z). (16) Using Equations (12)- (14), one can constrain the possible values of the axionlike particles mass m a and their coupling constant to nucleons g from (16).
The numerical analysis of (16) taking into account (12)- (14) and the values of ∆F C at different z [49] shows that the strongest constraints on m a and g follow at z = 3 µm, where ∆F C = 2.2 fN (see Section 4). These constraints are presented by the line labeled "new" in Figure 1. For comparison purposes, in the same figure, we show the constraints obtained earlier from the Cavendish-type experiment [93] (line "gr 1 " [94]), from measuring the smallest gravitational forces using the torsional oscillator [95][96][97] (line "gr 2 " [56]), from measuring the effective Casimir pressure [73,74] (line 1 [35] ), from the experiment using a beam of molecular hydrogen [98] (line "H 2 " [99]) and from the differential measurement where the Casimir force was completely nullified [59] (the dashed line [38]). Note that the figure field above each line is excluded and that below each line is allowed by the results of respective experiment.  Figure 1. The strongest constraints on the coupling constant of axionlike particles to nucleons obtained from different experiments. Lines labeled "gr 1 " and "gr 2 " are found from the Cavendishtype experiments and from measuring the minimum gravitational forces, respectively. Lines labeled "new" and "H 2 " follow from the recent experiment on measuring the Casimir force in the micrometer separation range and from the experiment using a beam of molecular hydrogen. Line 1 and the dashed line are obtained from measuring the effective Casimir pressure and from the experiment nullifying the Casimir force. The regions above each line are excluded, and those below are allowed.
As is seen in Figure 1, in the region of axion masses from 10 to 74 meV the constraints on g obtained from the experiment [49] (line "new") are stronger than those following from measuring the effective Casimir pressure (line 1) and the smallest gravitational forces (line "gr 2 "). The maximum strengthening up to a factor of 4 is reached for the axion mass m a ≈ 16 meV. Thus, in the region of axion masses indicated above, this experiment leads to stronger constraints than the previous experiments measuring the Casimir force [20,48]. The stronger constraints shown by the dashed line follow only from the experiment [59] where the Casimir force was completely nullified.

Constraints on Non-Newtonian Gravity
As mentioned in Section 1, the results of the experiment [49] measuring the Casimir force in the micrometer separation range can be also used for constraining the parameters of Yukawa-type corrections to Newtonian gravity. For this purpose, one should calculate the Yukawa-type force (8), (9) in the experimental configuration using its geometrical characteristics and densities of all constituting materials presented in Sections 3 and 4.
The calculation results using (8) and (9) for a homogeneous sphere above a homogeneous plate are presented in [41]. Here, we modify them in perfect analogy to [38,40] to take into account the contributions of Cr and Au layers covering both a sphere and a trench in this experiment. The result is where and the function Ψ is defined as By virtue of the fact that the Yukawa-type force (17) was not observed within the limits of the measurement error, it should satisfy the inequality |F Yu (z)| ∆F C (z). (20) Similar to the case of an additional interaction due to a two-axion exchange between nucleons, the strongest constraints on the parameters of the Yukawa-type interaction α and λ follow from (20) The constraints obtained are shown by the line labeled "new" in Figure 2. For comparison purposes, in this figure we also show the constraints following from measuring of the effective Casimir pressure [73,74] (line 1), of the normal Casimir force between sinusoidally corrugated surfaces of a sphere and a plate at different orientation angles of corrugations [100,101] (line 2 [102]) and of the lateral Casimir force force between the sinusoidally corrugated surfaces of a sphere and a plate [103,104] (line 3 [105]). Note that somewhat stronger constraints than those shown by line 3 were obtained [106] from the experiment measuring the Casimir force between crossed cylinders [107] on an undefined confidence level [31,54]. However, the strongest constraints on the parameters of a Yukawatype interaction in the region below λ = 10 −8 m follow from the experiments on neutron scattering. They are shown by the line labeled "n" [108,109]. Similar to Figure 1 In the region of Figure 2 with a larger λ, the constraints shown by line 4 are obtained from measuring the Casimir force by means of the torsion pendulum [110]. The line labeled "gr" indicates the constraints on the Yukawa-type interaction following from the Cavendishtype experiments [93,94,111]. As for the dashed line, which covers the largest interaction range, it is obtained [59] from the differential force measurement where the Casimir force was completely nullified (compare with the dashed line in Figure 1 found from the same experiment).
As seen in Figure 2, the constraints labeled "new" are stronger than the constraints of lines 1 and "gr" following from measurements of the effective Casimir pressure and from the Cavendish-type experiments over the interaction range from 550 nm to 4.4 µm. The maximum strengthening by up to a factor of 24 is reached at λ = 3.1 µm. The constraints obtained are weaker only as compared with those following from the experiment where the Casimir force was nullified [59].

Discussion
In this article, we considered the problems of dark matter axions, non-Newtonian gravity and the constraints on their parameters. As discussed in Section 1, axions and axionlike particles have gained much recognition as the most probable constituents of dark matter. An active search for axions using their interactions with photons, electrons, and nucleons is under way in many laboratories all over the world. A major contribution to the investigation of interactions between axions and photons in different astrophysical processes has been made by Prof. Yu. N. Gnedin, who suggested several prospective possibilities for the observation of axionlike particles and for constraining their parameters.
Here, we obtain new constraints on the coupling constant of axionlike particles to nucleons, which follow from the recently performed measurement of the differential Casimir force between Au-coated surfaces of the sphere and the top and bottom of rectangular trenches [49]. The differential character of this experiment allowed one to reach a very high precision and to obtain meaningful data up to a very large separation distance of 8 µm. The measure of agreement between the obtained data and the theoretical predictions based on first principles of quantum electrodynamics at nonzero temperature allowed us to find rather strong constraints on the axionlike particles and non-Newtonian gravity of Yukawa type.
The obtained constraints on the coupling constants of axionlike particles to nucleons are stronger by up to a factor of 4 than the previously known ones derived [56] from the gravitational experiments and from measuring the effective Casimir pressure [36,73,74]. This strengthening holds in the range of axion masses m a from 10 to 74 meV. We have also shown that the same experiment on measuring the differential Casimir force in the micrometer separation range [49] results in up to a factor of 24 stronger constraints on the interaction constant of Yukawa-type interactions compared with the ones found previously from measuring the effective Casimir pressure [73,74], an experiment using the torsion pendulum [110] and the Cavendish-type experiments [93,94,111]. In this case, the strengthening holds in the interaction range from λ = 550 nm to λ = 3.1 µm.
Although the constraints obtained are not the strongest ones (the strongest constraints on both the axionlike particles and the Yukawa-type interaction in the interaction ranges indicated above were obtained from the experiment [59] where the Casimir force was nullified), they complement the results found from previous measurements of the Casimir interaction and can be considered as their additional confirmation.
The obtained results fall into intensive studies of axionlike particles, non-Newtonian gravity and constraints on their parameters. In addition to the literature already discussed in Section 1, it is pertinent to mention a haloscope search for dark matter axions that excludes some range of the axion-photon couplings in models of invisible axions [112] and another haloscope experiment for the search of galactic axions using a superconducting resonant cavity [113]. The first results of the promising experiment for searching the dark matter axions with masses below 1 µeV are reported in [114]. Two more haloscope experiments are performed for the search of dark matter axions using their interaction with electronic spins [115] and photons [116].
A few prospective experiments for constraining the parameters of axionlike particles and non-Newtonian gravity are suggested in the literature but have not yet been performed. Here, one should mention an experiment measuring the Casimir pressure between parallel plates at up to 25-30 µm separations (Cannex) [117][118][119][120]. An approach for searching for dark matter axions with m a < 1 µeV using a superconducting radio frequency cavity was proposed in [121]. Several possibilities for probing the non-Newtonian gravity in a submillimeter interaction range by means of temporal lensing [122], molecular spectroscopy [123] and neutron interferometry [123,124] are also discussed. Finally, very recently, the possibility to detect the axion-nucleon interaction in the Casimir-less regime by means of levitated system was proposed [125]. According to the authors, their approach provides a possibility to strengthen the current constraints on g by several orders of magnitude in the wide region of axion masses from 10 −10 eV to 10 eV.

Conclusions
To conclude, the search for dark matter axions, non-Newtonian gravity and constraints on their parameters is a multidisciplinary problem of elementary particle physics, quantum field theory, gravitational theory, astrophysics and cosmology. At the moment, neither axions nor corrections to Newton's gravitational law, other than that predicted by General Relativity theory, are observed, but more and more stringent constraints on them have been obtained. Keeping in mind that there are very serious reasons for creating axions at the very early stages of the evolution of the universe and for existence of deviations from Newton's law of gravitation at very short separations, as predicted by the extended Standard Model, Supersymmetry, Supergravity and String theory, one may hope that these predictions will find experimental confirmation in the not too distant future.
Author Contributions: Investigation, both authors; writing, both authors. All authors have read and agreed to the published version of the manuscript.