Correction: Furugaito et al. Antimicrobial Susceptibility to 27 Drugs and the Molecular Mechanisms of Macrolide, Tetracycline, and Quinolone Resistance in Gemella sp. Antibiotics 2023, 12, 1538

The authors wish to make the following corrections to this paper [...].


Mutations in gyrA and gyrB
We analyzed the gyrA and gyrB sequences.The 35 quinolone-susceptible strains possessed gyrA, encoding GyrA with a serine residue at 83 (S83).The serine residue was substituted with leucine (S83L), phenylalanine (S83F), or tyrosine (S83Y) in the 21 quinoloneresistant strains.Specifically, two G. morbillorum strains possessed GyrA/S83L, encoding gyrA.Seven of the GH group, seven G. taiwanensis, and two G. sanguinis strains contained S83F.Two in the GH group and one G. taiwanensis strains contained S84Y.GyrB mutations associated with levofloxacin resistance were not detected (Table 5).
Levofloxacin resistance was associated with a substitution at serine 83 for leucine, phenylalanine, or tyrosine in GyrA.The mechanisms of resistance to erythromycin and clindamycin differed across Gemella species.In addition, the rate of susceptibility to levofloxacin differed across Gemella spp., and the quinolone resistance mechanism was caused by mutations in GyrA alone.

Figure 2 .
Figure 2. Distribution of erythromycin/clindamycin resistance in Gemella strains.Blue, yellow, and red boxes indicate sensitive, intermediate, and resistant, respectively.

Figure 2 .
Figure 2. Distribution of erythromycin/clindamycin resistance in Gemella strains.Blue, yellow, and red boxes indicate sensitive, intermediate, and resistant, respectively.

Table 5 .
Distribution of MIC of tested quinolones and amino acid substitutions in gyrA gene in quinolone-resistant Gemella isolates.

Table 2 .
Susceptibility to antimicrobial agents with breakpoints listed in CLSI M45-third edition.
a Interpretive breakpoints are shown in bold for each antibiotic.b NA, not applicable (breakpoints not established).c Antimicrobial agents with breakpoints listed in CLSI M45-third edition.

Table 3 .
Distribution of macrolides and clindamycin MICs and possession of the mef, erm, and msrA genes in erythromycin-non-susceptible Gemella isolates.

Table 4 .
Distribution of minocycline MIC and ermB in Gemella isolates harboring the tetM gene.

Table 5 .
Distribution of MIC of tested quinolones and amino acid substitutions in gyrA gene in quinolone-resistant Gemella isolates.