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Open AccessArticle

Graphene-Based Biosensors for Detection of Composite Vibrational Fingerprints in the Mid-Infrared Region

Fujian Provincial Key Laboratory of Optoelectronic Technology and Devices, Xiamen University of Technology, Xiamen 361024, China
College of Communication and Information Engineering, Xi’an University of Science and Technology, Xi’an 710054, China
Department of Electronic Science, Xiamen University, Xiamen 361005, China
Author to whom correspondence should be addressed.
Nanomaterials 2019, 9(10), 1496;
Received: 22 August 2019 / Revised: 9 October 2019 / Accepted: 17 October 2019 / Published: 20 October 2019
(This article belongs to the Special Issue Plasmonic Nanostructures and Related Applications)
In this study, a label-free multi-resonant graphene-based biosensor with periodic graphene nanoribbons is proposed for detection of composite vibrational fingerprints in the mid-infrared range. The multiple vibrational signals of biomolecules are simultaneously enhanced and detected by different resonances in the transmission spectrum. Each of the transmission dips can be independently tuned by altering the gating voltage applied on the corresponding graphene nanoribbon. Geometric parameters are investigated and optimized to obtain excellent sensing performance. Limit of detection is also evaluated in an approximation way. Besides, the biosensor can operate in a wide range of incident angles. Electric field intensity distributions are depicted to reveal the physical insight. Moreover, another biosensor based on periodic graphene nanodisks is further proposed, whose performance is insensitive to the polarization of incidence. Our research may have a potential for designing graphene-based biosensor used in many promising bioanalytical and pharmaceutical applications. View Full-Text
Keywords: label-free biosensors; metasurface; graphene; surface plasmons; nanophotonics label-free biosensors; metasurface; graphene; surface plasmons; nanophotonics
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MDPI and ACS Style

Cai, Y.; Hang, Y.; Zhou, Y.; Zhu, J.; Yang, J.; Wang, X. Graphene-Based Biosensors for Detection of Composite Vibrational Fingerprints in the Mid-Infrared Region. Nanomaterials 2019, 9, 1496.

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