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Article

Antibacterial Activity of Green-Synthesized Silver Nanoparticles Using Areca catechu Extract against Antibiotic-Resistant Bacteria

1
School of Health and Environmental Science, College of Health Science, Korea University, Seoul 02841, Korea
2
BK21 FOUR R&E Center for Learning Health Systems, Korea University, Seoul 02841, Korea
*
Author to whom correspondence should be addressed.
These authors contributed equally to this work.
Nanomaterials 2021, 11(1), 205; https://doi.org/10.3390/nano11010205
Received: 8 December 2020 / Revised: 31 December 2020 / Accepted: 12 January 2021 / Published: 14 January 2021
(This article belongs to the Special Issue Antibacterial Activity of Nanoparticles)
In this work, the antibacterial activity of silver nanoparticles (AgNPs) synthesized using Areca catechu extracts against three species of antibiotic-susceptible and three species of resistant bacteria was investigated. The effects of this plant were more promising when compared with other medicinal plants tested. The hydrothermal extract of Areca catechu was mixed with silver nitrate to synthesize AgNPs. The synthesized particle characteristics were analyzed by UV–Vis spectrophotometry, scanning electron microscopy (SEM), dynamic light scattering (DLS), and Fourier-transform infrared spectroscopy (FT-IR). Minimum inhibitory concentration and minimum bactericidal concentration tests were conducted to confirm antibacterial activity and the results showed that AgNPs synthesized using Areca catechu extracts effectively inhibited the growth of bacterial species. Moreover, the SEM images of the bacterial species treated with AgNPs synthesized with Areca catechu extracts showed that clusters of AgNPs were attached to the surface of the bacterial cell wall, which could induce destruction of the cell membranes. The results suggest that AgNPs synthesized with Areca catechu extracts have the potential to treat antibiotic-resistant bacteria known as the major cause of nosocomial infections. View Full-Text
Keywords: green synthesis; silver nanoparticle; Areca catechu; antibiotic-resistant bacteria; antibacterial activity green synthesis; silver nanoparticle; Areca catechu; antibiotic-resistant bacteria; antibacterial activity
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MDPI and ACS Style

Choi, J.S.; Jung, H.C.; Baek, Y.J.; Kim, B.Y.; Lee, M.W.; Kim, H.D.; Kim, S.W. Antibacterial Activity of Green-Synthesized Silver Nanoparticles Using Areca catechu Extract against Antibiotic-Resistant Bacteria. Nanomaterials 2021, 11, 205. https://doi.org/10.3390/nano11010205

AMA Style

Choi JS, Jung HC, Baek YJ, Kim BY, Lee MW, Kim HD, Kim SW. Antibacterial Activity of Green-Synthesized Silver Nanoparticles Using Areca catechu Extract against Antibiotic-Resistant Bacteria. Nanomaterials. 2021; 11(1):205. https://doi.org/10.3390/nano11010205

Chicago/Turabian Style

Choi, Jeong S., Hyon C. Jung, Yeon J. Baek, Bo Y. Kim, Min W. Lee, Hyeong D. Kim, and Suhng W. Kim. 2021. "Antibacterial Activity of Green-Synthesized Silver Nanoparticles Using Areca catechu Extract against Antibiotic-Resistant Bacteria" Nanomaterials 11, no. 1: 205. https://doi.org/10.3390/nano11010205

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