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Journal of Functional Biomaterials
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Journal of Functional Biomaterials, Volume 10, Issue 4

December 2019 - 13 articles

Cover Story: Alterations in the implant macrogeometry may improve the osseointegration process. New concepts about bone tissue compression during implant installation are being established, especially in order to generate as little stress as possible during the insertion of implants in this tissue. Thus, the elaboration of the healing chambers in the implant body (macrogeometry) was an excellent alternative for less compression of bone tissue without losing the fundamental characteristics necessary for the primary stability of these implants. View this paper.
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Articles (13)

  • Article
  • Open Access
28 Citations
6,520 Views
15 Pages
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Impact of Bi2O3 and ZrO2 Radiopacifiers on the Early Hydration and C–S–H Gel Structure of White Portland Cement

  • Qiu Li and
  • Nichola J. Coleman
J. Funct. Biomater.2019, 10(4), 46;https://doi.org/10.3390/jfb10040046

18 October 2019

Bismuth oxide (monoclinic α-Bi2O3) and zirconium oxide (monoclinic ZrO2) are the most popular radiopacifiers in commercial Portland cement-based endodontic restoratives, yet their effects on the setting and hydration reactions are not fully und...

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  • Article
  • Open Access
7 Citations
6,317 Views
17 Pages
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Cell-Penetrating Peptides as a Tool for the Cellular Uptake of a Genetically Modified Nitroreductase for use in Directed Enzyme Prodrug Therapy

  • Simon D. Anderson,
  • Robert J. Hobbs,
  • Vanessa V. Gwenin,
  • Patrick Ball,
  • Lindsey A. Bennie,
  • Jonathan A. Coulter and
  • Chris D. Gwenin
J. Funct. Biomater.2019, 10(4), 45;https://doi.org/10.3390/jfb10040045

1 October 2019

Directed enzyme prodrug therapy (DEPT) involves the delivery of a prodrug-activating enzyme to a solid tumour site, followed by the subsequent activation of an administered prodrug. One of the most studied enzyme–prodrug combinations is the nit...

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  • Article
  • Open Access
39 Citations
10,464 Views
35 Pages
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An Insight into Advanced Approaches for Photosensitizer Optimization in Endodontics—A Critical Review

  • Patrícia Diogo,
  • M. Amparo F. Faustino,
  • M. Graça P. M. S. Neves,
  • Paulo J. Palma,
  • Isabel P. Baptista,
  • Teresa Gonçalves and
  • João Miguel Santos
J. Funct. Biomater.2019, 10(4), 44;https://doi.org/10.3390/jfb10040044

30 September 2019

Apical periodontitis is a biofilm-mediated disease; therefore, an antimicrobial approach is essential to cure or prevent its development. In the quest for efficient strategies to achieve this objective, antimicrobial photodynamic therapy (aPDT) has e...

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