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Article

Increased Risk of Temporomandibular Joint Disorder in Patients with Rheumatoid Arthritis: A Longitudinal Follow-Up Study

by 1,2, 3, 2,3,4,* and 2,5,*
1
Department of Oral & Maxillofacial Surgery, Dentistry, Hallym University College of Medicine, Anyang 14068, Korea
2
Research Center of Clinical Dentistry, Hallym University Clinical Dentistry Graduate School, Chuncheon 24252, Korea
3
Hallym Data Science Laboratory, Hallym University College of Medicine, Anyang 14068, Korea
4
Department of Otorhinolaryngology-Head & Neck Surgery, Hallym University College of Medicine, Anyang 14068, Korea
5
Department of Otorhinolaryngology-Head & Neck Surgery, Hallym University College of Medicine, Dongtan 18450, Korea
*
Authors to whom correspondence should be addressed.
J. Clin. Med. 2020, 9(9), 3005; https://doi.org/10.3390/jcm9093005
Received: 21 August 2020 / Revised: 14 September 2020 / Accepted: 15 September 2020 / Published: 17 September 2020
We evaluated the incidence of temporomandibular disorder (TMD) in patients with rheumatoid arthritis (RA) and examined the association between TMD and RA, through longitudinal follow-up. Population data from the Korean National Health Insurance Service-Health Screening Cohort from 2002 to 2015 was used. From 514,866 subjects, 3122 with RA were matched with 12,488 controls in a 1:4 ratio. The crude and adjusted models (for obesity, smoking, alcohol consumption, blood pressure, blood glucose, total cholesterol, and Charlson Comorbidity Index scores) were calculated. Chi-square tests, Kaplan-Meier (KM) analysis, and two-tailed analyses were used for statistical analysis. Stratified Cox proportional hazard models were used to assess the hazard ratios (HR) and 95% confidence intervals (CI) for TMD in the RA group, compared to those in the control group. The adjusted HR for TMD in RA was 2.52 (95% CI = 1.70–3.74), compared to the control group. The results were consistent with the subgroup analyses, according to age and sex, except in men older than 60 years of age. KM analysis showed similar results. Hence, we found that patients with RA have a higher risk of TMD, and should be observed for symptoms of the initial stage of TMD to prevent the risk of aggravation. View Full-Text
Keywords: temporomandibular joint; TMJ; TMD; disorder; rheumatoid arthritis temporomandibular joint; TMJ; TMD; disorder; rheumatoid arthritis
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MDPI and ACS Style

Byun, S.-H.; Min, C.; Choi, H.-G.; Hong, S.-J. Increased Risk of Temporomandibular Joint Disorder in Patients with Rheumatoid Arthritis: A Longitudinal Follow-Up Study. J. Clin. Med. 2020, 9, 3005. https://doi.org/10.3390/jcm9093005

AMA Style

Byun S-H, Min C, Choi H-G, Hong S-J. Increased Risk of Temporomandibular Joint Disorder in Patients with Rheumatoid Arthritis: A Longitudinal Follow-Up Study. Journal of Clinical Medicine. 2020; 9(9):3005. https://doi.org/10.3390/jcm9093005

Chicago/Turabian Style

Byun, Soo-Hwan, Chanyang Min, Hyo-Geun Choi, and Seok-Jin Hong. 2020. "Increased Risk of Temporomandibular Joint Disorder in Patients with Rheumatoid Arthritis: A Longitudinal Follow-Up Study" Journal of Clinical Medicine 9, no. 9: 3005. https://doi.org/10.3390/jcm9093005

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